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目的探讨在术前任务态功能磁共振（T-fMRI）中，胶质瘤侵犯中央前回对双侧大脑半球激活斑的影响。方法将56例接受了术前任务态磁共振扫描的胶质瘤患者分为中央前回侵犯组（PGI， n=21）和中央前回无侵犯组（PGNI， n=35）。我们设定了三个不同的体素水平上的统计阈值（P值：P1，10-4；P2，10-6；P3，10-8），并获得相应统计水平的大脑激活图（V1， V2和V3）。分别计算双侧大脑半球间（瘤侧/对侧：IAVR）和双侧中央前回间的激活斑体积比值（瘤侧/对侧：PAVR）。计算位于不同统计阈值区间的激活斑体积（△V1=V1-V2；△V2 = V2-V3），并进一步比较它们在双侧大脑半球间的比值［△Vn（瘤侧）/△Vn′（对侧），n= 1，2］。此外，我们还分析了肿瘤特征与IAVR和PAVR间的关系。结果在相对较低的统计阈值水平中（P1 和 P2），相较于PGNI组，PGI组的IAVR和PAVR明显减低（P＜0.05），但在较严格的统计阈值中（P3），这两组间则无明显差异。相比PGNI组，PGI组的△V1/△V1’明显减低（P=0.02），但△V2/△V2’在两组间没有差异。此外，在PGI组，PAVR与肿瘤大小呈负相关（P=0.043），并且肿瘤距手节区的距离与IAVR和PAVR呈正相关（P＜0.05）。结论相比胶质瘤未侵犯功能区，在T-fMRI中，侵犯功能区会更容易影响肿瘤同侧脑半球中较低统计阈值的激活斑，造成双侧大脑半球间激活斑不对称性，但这种影响在更严格的统计阈值中没有出现。选取多个统计阈值来分析胶质瘤术前T-fMRI的激活斑结果是十分必要的。

目的本研究拟探讨结构性MRI测量对脊髓小脑共济失调3型（SCA3）的诊断价值，并进一步评估其与疾病的严重程度及病程的相关性。方法前瞻性收集2018 年5月至2021年11月于中山大学附属第一医院经基因诊断确诊的SCA3患者81例（症状组（sym-SCA3）：59，症状前组（pre-SCA3）：22，同时收集年龄、性别匹配的正常对照（HCs）35例。受试者均采集MRI结构像（3D T1WI MPRAGE）并收集其相应的临床资料。三位具不同临床经验的观察者分别通过第三方软件测量双侧小脑上、中、下脚宽度、脑桥及不同平面脊髓前后径（平枕骨大孔、颈3-5椎体上缘），其中一位观察者2个月后对上述指标进行重复测量。分别计算观察者内及观察者间可重复性，采用单因素方差分析、秩和检验、ROC曲线及随机森林方法评估上述指标对SCA3的诊断价值，并与临床资料进行相关性分析。结果基于形态学MRI脑结构测量指标，无论是观察者内或观察者间，均具有较高的可重复性且不依赖于观察者的临床经验，其中双侧小脑上、中脚具有最高的一致性。HCs、pre-SCA3和sym-SCA3三组的双侧小脑上、中、下脚、脑桥及脊髓前后径（除颈5椎体上缘水平）分别依次减小并具有统计学差异（PP

目的分析急性脑梗死患者治疗前一站式CT灌注成像（CTP）及治疗前后临床影像资料，明确与预后相关的临床及影像特征。方法纳入CT/MRI 随访证实的39例急性脑梗死患者（男：女= 21：18，平均年龄65岁，平均起病时间8.4 h），所有患者均随访90天获取其mRS评分（平均2.8分）。对上述患者行320排螺旋CT一站式CTP［非增强CT（NCCT）-CT血管成像（CTA）-CTP］扫描，对NCCT图像行ASPECTS（alberta stroke program early ct score）评分，经后处理获得脑血管图，脑梗死核心区、缺血半暗带体积以及其相应比值，并获得CTP各灌注参数图［CBF，CBV，MTT，TTP，延迟达峰时间（Delay-TTP）］。将大小一致的感兴趣区分别放置在脑梗死核心区、缺血半暗带及其相应对侧脑实质，分别测量3次，取平均值。结果39例患者中，20例预后良好 （mRS ≤2）。相关分析发现，治疗前后NIHSS评分、梗死核心体积、缺血半暗带MTT及相应区域Delay-TTP 与随访90天mRS评分成明显正相关（P≤0.04）；而治疗后ASPECTS评分及梗死核心区CBF值与90 d mRS评分成明显负相关（P< 0.05）。进一步两组对比分析发现，治疗前后NIHSS、治疗后ASPECTS、CTP示梗死核心区体积及梗死核心CBF值与患者预后明显相关并具有统计学差异（P≤0.03）。ROC分析显示治疗后NIHSS评分对于预测急性脑梗死患者预后有着最高的诊断效能（AUC为0.90），其中敏感度、特异度及拐点值分别为79%，85%和4.5；而梗死核心区CBF具有最佳的特异度（89%），治疗后ASPECTS评分在预测预后方面具有最高的敏感度（94%）。结论急性脑梗死患者梗死核心区体积、CBF、治疗前后NIHSS及治疗后ASPECTS评分与患者的预后密切相关。相比较NIHSS评分，梗死核心区CBF对于预测急性脑梗死预后有着更高的特异度。

目的对比分析基于不同扩散模型的扩散加权成像（扩散张量成像：DTI，扩散峰度成像：DKI，和神经突起方向离散度与密度成像：NODDI）在脑胶质瘤术前预测脑胶质瘤级别和异柠檬酸脱氢酶-1（IDH-1）突变的诊断效能。方法回顾性分析中山大学附属第一医院2014年5月至2019年12月经手术病理证实的胶质瘤患者66例（WHO Ⅱ级28例，Ⅲ级10例，Ⅳ级28例），其中IDH-1基因表型明确的患者64例（IDH-1突变型34例，野生型30例）。采用德国西门子Magnetom Verio 3.0T MRI机器进行数据采集，扫描序列包括常规MRI平扫，增强和扩散加权成像。后处理获取DTI（平均扩散系数：MD，部分各向异性分数：FA），DKI（平均峰度：MK，轴向峰度： Ka，径向峰度：Kr）和NODDI（神经突内体积分数：icvf，神经突方向离散度：odi）的各参数图。用Image J勾画肿瘤实质相邻最大的三个层面作为ROI，取得各个参数的均值。采用独立样本t检验或Mann-Whitney秩和检验分别比较高、低级别组和不同IDH-1状态各扩散参数值的差异。进一步，对有统计学意义差异的参数进行Logistic回归分析，评价其鉴别脑胶质瘤高低级别和IDH-1基因突变状态的诊断效能，并获得受试者工作特征（ROC）曲线。结果基于不同的扩散加权模型，其扩散参数均可以用于区分脑胶质瘤级别（PAUC=0.88，AUC 95%CI（0.79，0.96）］优于单一的MK参数。对IDH-1基因突变状态预测，NODDI两个参数均无鉴别意义，DKI和DTI的各参数可有效鉴别（PIDH-1突变，回归模型ROC曲线下面积［AUC=0.72，AUC 95%CI（0.59， 0.85）］。结论基于不同扩散模型的扩散加权成像均可以用于预测脑胶质瘤级别，DKI诊断价值最优；对于IDH-1突变状态的预测，DKI优于DTI，而NODDI价值有限。推荐DKI用于临床脑胶质瘤术前评估。

This paper summarized the practice of appropriate technology and nursing of Traditional Chinese Medicine in a patient with diabetic peripheral neuropathy combined with lower limb pain. Based on the nursing risk assessment and syndrome differentiation, scraping therapy, Bian-stone hot ironing-massage and Chinese herbal medicine penetration, Chinese medicine foot bath were carried out to relieve the lower limb pain and anxiety of the patient. (本文总结1例中医护理适宜技术治疗糖尿病周围神经病变合并下肢疼痛的护理经验。基于护理评估结果以及辨证分型, 采取刮痧、砭石熨摩中药透入法以及中药足浴护理干预, 明显减轻患者下肢疼痛的症状, 缓解了焦虑情绪。)

This article summarized the nursing care of a patient with head and neck squamous cell carcinoma (HNSCC) complicated with immune-related myositis. Nursing points included: nursing care on bilateral ptosis and dysphagia, the patient’s safety management and psychological nursing, health education on corticosteroids therapy, etc. Trough symptomatic treatment with integrated traditional Chinese and western medicine and individual nursing care, the patient’s condition was relieved, and the patient was discharged smoothly. (本总结1例头颈部鳞癌患者并发免疫相关性肌炎的护理经验。护理要点包括: 双眼睑下垂和吞咽困难的护理、安全管理和心理护理、眼周穴位按摩联合皮内针疗法、健康宣教等。通过中西医结合对症治疗以及个性化护理, 患者病情缓解并顺利出院。)

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Traditional Chinese Drug Research & Clinical Pharmacology is the property of Traditional Chinese Drug Research & Clinical Pharmacology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In this study, the compound 1-(4-(tert-butyl) phenyl)-3-hydroxy-2-methylpyridine-4 (1H) - one (hereinafter referred to as HAINU-19) was used as the active ingredient to prepare the microemulsion and determine its antifungal activity. First, through the screening solvents, co-solvents, and transparent, the formulation of 2.5% HAINU-19 microemulsion (mass fraction) was determined as follows: 2.5% HAINU-19, 15% ethanol, 10% cyclohexanone, 20% transparent (1601# : 500# : AC1810 = 3 : 3 : 1), with distilled water making up to 100%. All indicators meet national standards. The bioassay result of pot experiments showed that the protective and curative effects of 2.5% HAINU-19 microemulsion on wheat stripe rust were 100% at 1000, 500, and 250-fold dilutions, and curative effects were 76.67%, 81.00%, and 82.33%, respectively. The field trial results showed that the 2.5% HAINU19 microemulsion had a control efficacy of 86.13% on rice sheath blight at a 100-fold dilution and 71.24% at a 200-fold dilution. This study can provide an experimental basis and technical support for the development and application of the antifungal compound HAINU-19. [ABSTRACT FROM AUTHOR]

利用电感耦合等离子体质谱（ICP-MS）仪对回收油脂与食用植物油中27种元素含量进行分析检测，了解回收油脂与食用植物油中27种元素含量的差异，以此鉴别回收油脂与食用植物油。采集合格食用植物油样品22份，回收油脂样品120份，经微波消解后，进入ICP-MS仪检测27种元素含量，结合偏最小二乘法判别分析进行元素差异分析，找出不同类型回收油脂与食用植物油的特殊差异元素。结果表明：Co、Cu、Fe、Na、Mn在未精炼回收油脂和食用植物油中的含量差异较大，可以作为鉴别未精炼回收油脂和食用植物油的指标元素；Fe、Cd两种元素在精炼回收油脂和食用植物油中的含量差异较大，可用于精炼回收油脂的鉴别；Cr、Cd、Ag、Ca、Pb、Hg、Al含量在不同颜色精炼回收油脂中有明显差异，可以此来指导回收油脂的进一步提炼，并根据其元素含量的高低用于生物原油等再利用。研究结果可为回收油脂与食用植物油的鉴别提供参考。 The 27 elements in recycled oils and edible vegetable oils were analyzed by inductively coupled plasma mass spectrometry (ICP-MS) to determine the differences in the 27 elements contents in recycled oils and edible vegetable oils, and identify recycled oils from normal edible vegetable oils. The samples of 22 qualified edible vegetable oils and 120 recycled oils were collected,and the contents of 27 elements were analyzed by ICP-MS after microwave digestion. The element content difference analysis was carried out using partial least squares discriminant analysis to identify specific elements between different types of recycled oils and edible vegetable oils.The results showed that Co，Cu，Fe，Na and Mn were very different between crude recycled oils and edible vegetable oils，which could be used to identify crude recycled oils. The contents of Fe and Cd were very different in refined recycled oils and edible vegetable oils, which could be used to identify refined recycled oils. The contents of Cr, Cd, Ag, Ca, Pb, Hg and Al were significantly different in refined recycled oils with different color，which could guide the further extraction and refining, and the reuse of crude bio-oil according to the level of its element content.The results could provide a reference for the identification of recycled oils from edible vegetable oils.

This article explores the construction plan and innovative operation mode of Peripherally Inserted Central Catheter (PICC) nursing clinics in a certain Traditional Chinese Medicine(TCM) hospital, and to evaluate its practical effects. The PICC nursing clinic had a reasonable layout, and the work was carried out through the formation of intravenous treatment teams, establishment of rules and regulations, nursing expert preparation system, multi-disciplinary team cooperation system, special quality control of outpatient clinics, application of characteristic Chinese Medicine technology, and networked nursing guidance, etc. (本文探讨了中医医院PICC护理门诊的建设方案和创新运行模式, 并评价其实践效果。PICC护理门诊设置布局合理, 通过组建静脉治疗团队, 通过建章立制、护理专家备班制、多学科团队合作制、门诊专项质量控制、应用中医特色技术及网络化护理指导等形式开展工作。)

Objective To investigate the association of sleep disorders with the development and progression of nonalcoholic fatty liver disease (NAFLD). Methods A total of 1 868 participants from the health examination cohort and fatty liver cohort of Beijing Friendship Hospital from June 2022 to June 2023 were enrolled as subjects. Related data were collected from all subjects. including age, sex, education level, chronic medical history, and biochemical parameters, and all subjects completed Pittsburgh Sleep Quality Index (PSQI) scale independently. According to the diagnostic criteria, the subjects were divided into non-NAFLD group with 1 122 subjects and NAFLD group with 746 subjects, and according to the stage of progression, the patients in the NAFLD group were further divided into simple fatty liver group (SFL group with 624 subjects) and nonalcoholic steatohepatitis (NASH) group with 122 subjects. A one-way analysis of variance or the Kruskal-Wallis H test was used for comparison of continuous data between three groups. The chi-square test was used for comparison of categorical data between the three groups. The binary Logistic regression analysis was used to investigate the association between sleep factors and NAFLD, and the multinomial Logistic regression analysis was used to investigate the association between sleep factors and the different stages of NAFLD; two multivariate models were constructed for adjustment of potential confounding factors, i, e., an age-sex adjustment model and a multivariate adjustment model, and the multivariate adjustment model adjusted the factors of age, sex, education level, smoking, diabetes, hypertension, body mass index (BMI), triglyceride (TG), and high-density lipoprotein cholesterol (HDL-C). Results There were significant differences in age, sex, BMI, education level, smoking, diabetes, hypertension, alanine aminotransferase, TG. and HDL-C between the non-NAFLD, SFL, and NASH groups (all P<0.05). There were also significant differences between the three groups in the total score of PSQI scale and the proportion of subjects with a score of 0-3 points for the 7 sleep components (all P< 0.05). The multivariate adjustment model showed no significant association between sleep disorders and SFL, while long sleep latency (odds ratio [OR] =4.04. 95% confidence interval [Cl]: 2.33-7.03, P<0.001), short sleep duration (OR=3.53, 95%CI: 1.83-6.82. P<0.001), and severe sleep disorders (OR=2.96, 95%CI: 1.48-5.93, P=0.002) were closely associated with the risk of NASH. Conclusion Overall sleep condition and its components of sleep disorders are not significantly associated with the simple fatty liver; however, long sleep latency, short sleep duration, and severe sleep disorders can increase the risk of NASH, which should be taken seriously in clinical practice. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Ordnance Equipment Engineering is the property of Chongqing University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Lung nodules occupy fewer pixels in CT (Computed Tomography), which brings great difficulty to detection. In view of small target detection of lung nodule, this study proposes YOLOV3 (You Only Look Once version 3) lung nodule detection algorithm based on coordinate attention. The backbone network adopts the improved YOLOv3, reduces the number of residual blocks and introduces the dilated convolution module to sense context information around the target. In the feature utilization, coordinate attention is introduced to capture the position, direction and cross channel information, so as to locate lung nodules accurately. The loss function of YOLOv3 is improved, the boundary box is modeled as Gaussian distribution. Wasserstein distance is used to calculate the similarity between the two distributions instead of IoU (Intersection over Union), so as to improve the sensitivity of the target scale. The results on LUNA16 show that the average precision is 89.96% and the sensitivity is 95.37%. Compared with mainstream target detection algorithms, the precision and sensitivity of the proposed method are improved by 11.33% and 9.03%, respectively. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Computer-Aided Design & Computer Graphics / Jisuanji Fuzhu Sheji Yu Tuxingxue Xuebao is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Science Technology & Engineering is the property of Chinese Society of Technology Economics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Science Technology & Engineering is the property of Chinese Society of Technology Economics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To analyze the clinical and genetic characteristics of three children with congenital heart defects, dysmorphic facial features and intellectual developmental disorders(CHDFIDD).Methods Three children presenting with CHDFIDD were enrolled. Genomic DNA was extracted from peripheral venous blood of the children and their parents. Whole-exome sequencing (WES)was performed using chip-capture high-throughput sequencing technology. Suspected causative mutations were verified by Sanger sequencing and bioinformatic analysis.Using"CDK13 gene"and"CDK13-related diseases" as search terms, literatures of CNKI and Wanfang database were retrieved until February 2024.Using"CDK13","CDK13-related disorder" and "CHDFIDD" a s search terms, literatures from the establishment of PubMed database untio February 2024 was retrieved, and the relevant literature was reviewed. Results WES revealed heterozygous variants of the CDK13 gene in three children, including c.2572 C>T(p.Leu858Phe), c.2579 G>A(p.Arg860Gln), and c.2602C>T(p.Arg868Trp), which were verified as de novo variants by Sanger sequencing. Combined with the clinical phenotype, all 3 children were diagnosed with CHDFIDD. However, the possibility that one of the affected children's parents was a germline chimera for the mutation could not be excluded. According to the ACMG guidelines, all three mutation sites were classified as likely pathogenic. A total of 14 studies consisting of 108 cases were retrieved. Among them, c.2572C>T has not been reported. Conclusions The de novo variants of the CDK13 gene may be the genetic cause of developmental delay/intellectual disability in these three children. The findings in the present study expand the spectrum of CDK13 gene mutations, providing reference for the diagnosis of CHDFIDD. [ABSTRACT FROM AUTHOR]

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Copyright of Journal of South China Normal University (Natural Science Edition) / Huanan Shifan Daxue Xuebao (Ziran Kexue Ban) is the property of Journal of South China Normal University (Natural Science Edition) Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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[Objective] In order to explore the impact of tree canopy density on the growth of Chimonobambusa quadrangularis, expand the space for artificial planting of Chimonobambusa quadrangularis, and improve forest productivity. [Method] An experiment was conducted at the Shuifu Tongluoba Bamboo Industry Professional Cooperative to plant Chimonobambusa utilis Rongmao Fangzhu under the forest. Five small areas with different canopy densities were designed for the upper layer of trees, and two treatments were used; non covered plastic film and covered plastic film. After planting for one year, a random sampling method was used to select 10 clusters of bamboo, and their bamboo ground diameter, height, number of bamboo shoots, number of shooting shoots and diameter of bamboo shoots were investigated. [Result] The results showed that without covering plastic film, the average ground diameter of bamboo was 2.27 mm/clump, the average height of bamboo was 0.28 m/clump, the average number of bamboo shoots was 5.14, the average number of shooting shoots was 3.52, and the average ground diameter of bamboo shoots was 3.92 mm/clump; When covered with plastic film, the average ground diameter of bamboo is 2.77 mm/clump, the average height of bamboo is 0.33 m/clump, the average number of bamboo plants is 3.98, the average number of bamboo shoots is 2.88, and the average ground diameter of bamboo shoots is 4.52 mm/clump. [Conclusion] Through F-test and other analysis, the following conclusions are drawn the canopy density of the upper layer arbor forest has a significant impact on the diameter growth, height growth, number of mature bamboo trees, number of shoots, and ground diameter of bamboo shoots within one year of planting. However, by covering with plastic film, the impact of the canopy density of the upper layer arbor on the growth of Chimonobambusa utilis Rongmao Fangzhu can be reduced, especially the impact of the high canopy density of the upper layer arbor on the growth of Chimonobambusa utilis Rongmao Fangzhu. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Energy Chemical Industry is the property of Energy Chemical Industry Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Shaanxi University of Science & Technology is the property of Journal of Shaanxi University of Science & Technology Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Computer-Aided Design & Computer Graphics / Jisuanji Fuzhu Sheji Yu Tuxingxue Xuebao is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Dalian Ocean University is the property of Journal of Dalian Ocean University Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Sedimentologica Sinica is the property of Acta Sedimentologica Sinica Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的　探讨重组人干扰素 α2b (rhIFNα2b) 喷雾剂联合炎琥宁注射液对小儿病毒性肺炎的治疗效果及患 儿免疫功能变化. 方法　选取病毒性肺炎住院患儿250例，依据治疗方法不同分为观察组和对照组各125例，两组 性别, 年龄构成以及治疗前血液免疫细胞, 血清免疫球蛋白及炎症因子水平比较差异无统计学意义. 观察组予 rhIFNα2b喷雾剂联合炎琥宁注射液治疗，对照组单独给予炎琥宁注射液治疗，两组疗程均为7 d. 治疗过程中记录 患儿完全退热时间，记录咳嗽, 喘息, 湿啰音等症状持续时间以及不良反应发生情况. 疗程结束后评价临床疗效， 观察治疗前后两组血液免疫细胞, 血清免疫球蛋白及炎症因子水平变化. 结果 250 例患儿剔除不配合治疗及 外院治疗者，最终入组有效病例 244 例，其中观察组 124 例，对照组 120 例. 观察组治疗总有效率 (90. 32%) 高于 对照组 (76. 67%) ，观察组完全退热时间以及喘憋, 咳嗽, 肺部啰音等症状持续时间较对照组缩短，差异均有统计 学意义 (P均<0. 05) . 与对照组比较，治疗后观察组血液CD3+, CD8+ 细胞比例及血清免疫球蛋白 IgM, IgG, IgA 水平 升高，CD4+ 细胞比例, CD4+ /CD8+ 及血清炎症因子 TNF-α, IL-6, IL-8 水平降低，差异均有统计学意义 (P 均<0. 05) . 结论 rhIFNα2b 喷雾剂联合炎琥宁注射液治疗小儿病毒性肺炎临床疗效及安全性良好，其机制与改善患儿机体 免疫功能及减轻炎症反应程度有关. [ABSTRACT FROM AUTHOR]

Copyright of Diagnostic Imaging & Interventional Radiology is the property of Editorial Office of Diagnostic Imaging & Interventional Radiology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In view of the problem that natural sand is increasingly exhausted, Yellow River sand and desert sand were used to replace natural sand to prepare mortar respectively. The strength development mechanism of the two kinds of mortar was revealed from the macro and micro perspectives by means of scanning electron microscope ( SEM), energy dispersive spectrometer ( EDS) and back scatter electrons ( BSE) and elemental scanning microscopic characterization and mechanical strength test. The results show that the ettringite ( AFt) and calcium silicate hydrate ( C-S-H) at the interface of cement sand in the desert sand system are well developed, and a large number of layered Ca(OH)2 are closely accumulated in the early stage of curing, strengthening the interface structure of cement sand. The Ca / Si ratio of desert sand mortar increased by 1. 64 with age, and the Ca / Si ratio of Yellow River sand mortar increased by 0. 52, effectively ensuring its strength stability; Desert sand particles have strong cohesiveness, fully fill the pores of mortar interface, optimize the compactness of mortar structure, and thus improve its mechanical strength. [ABSTRACT FROM AUTHOR]

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Copyright of Journal of Computer Engineering & Applications is the property of Beijing Journal of Computer Engineering & Applications Journal Co Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)