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Capsule warning syndrome (CWS) is a group of rare clinical symptoms with frequent episodes of stereotyped neurological deficits, and easy progression to complete stroke. This study reported a case of CWS with paroxysmal speech inarticulateness and left limb weakness. Within 24 hours after intravenous thrombolysis with alteplase, the patient still had repeated episodes of stereotypical speech inarticulateness and left limb weakness. After assessing the risk, tirofiban was given within 24 hours after intravenous thrombolysis, and dual antiplatelet therapy was bridged 3 days later. The patient had no recurrence of neurological deficits. However, the timing of initiation of dual antiplatelet therapy after intravenous thrombolysis and the dual antiplatelet therapy program still need large-scale data to further explore. [ABSTRACT FROM AUTHOR]

Objective: To establish a Kunming mouse model of encephalomyocarditis virus （EMCV） infection. Methods: Kunming mouse aged 6~8 weeks, half male and female, were divided into control group and EMCV high （100 TCID50/20 g）, medium（10 TCID50/20 g） and low（1 TCID50/20 g） doses groups. The mice were weighed on 5 d, 7 d, 9 d, 11 d, 13 d and 15 d of EMCV infection. After blood was collected from the orbit, the rats were sacrificed by severed neck. The organ indexes of the heart, brain, liver and spleen were calculated; qRT-PCR was used to detect the viral loads in the heart, brain, spleen, liver and peripheral blood; qRT-PCR was used to detect the expressions of IL-1β, IL-6 and TNF-α mRNA in the heart and brain; HE staining was used to observe the pathological damage of heart and brain tissues. Results: Compared with the control group, high dose of EMCV could significantly increase the heart index（P<0.05） and extremely significantly increase spleen index（P<0.01） when mice were infected with EMCV for 5 d; results of qRT-PCR showed that the viral loads in the heart, brain, liver, spleen and peripheral blood of mice were the highest at 9 d after high-dose EMCV infection, and the viral loads in various organs of mice infected with medium and low doses of EMCV were very low; when high-dose EMCV infected mice for 9 d, the levels of IL-1β（P<0.01）, IL-6（P<0.001） and TNF-α （P<0.01） in heart and brain were significantly increased; high-dose EMCV infection for 9 d caused infiltration of inflammatory cells and vacuolated lesions in cardiac tissues. High-dose EMCV infection for 5~9 d caused thickening of the meninges in the brain tissues, dilation and hemorrhage of submeningeal blood vessels, dilation of white matter blood vessels and the formation of vascular sleeves. Conclusion: When the EMCV infection dose is 0.2 ml 100 TCID50/20 g, the Kunming mouse model of EMCV infection is successfully established. [ABSTRACT FROM AUTHOR]

Local feature information plays an important role in image segmentation, however, the referring image segmentation task is dependent on the text expression, so it is impossible to extract local feature information directly from the original reference image. In order to solve this problem, this paper proposes a specific noun-guided local feature extraction deep neural network model（NgLFNet). The NgLFNet model can automatically mine the local feature information of the object to be segmented according to the key nouns in the input text expression. Specifically, the model first obtains key nouns in text through sentence analysis; secondly, extracting corresponding features through text and image encoders, and using the key nouns to obtain local features of high-interest regions through the multihead attention mechanism; then the multi-modal features are gradually fused to learn; Finally, the decoding and correction module uses the obtained local features to perform more detailed corrections on the prediction mask to obtain the final result. The method in this paper is compared with a variety of mainstream referring segmentation methods and the experimental results show that the proposed method improves the accuracy of text-based instance segmentation task. [ABSTRACT FROM AUTHOR]

Objective To investigate the short-term poor prognosis and its influencing factors of patients with acute ischemic stroke, in order to provide reference for the formulation of measures to improve the prognosis. Methods The patients with acute ischemic stroke who were hospitalized in the hospital from December 2020 to March 2022 were selected, and they were divided into the good prognosis (≤2 points) group and the poor prognosis (≥3 points) group according to the prognosis situation (Modified Rankin Scale score on the 21st day of onset) . Then the clinical data of the two groups were compared, and the influencing factors of short-term prognosis of patients were analyzed by multivariate logistic regression analysis. Results A total of 61 patients were finally included, including 35 in the good prognosis group and 26 in the poor prognosis group. The univariate analysis showed that complications (P=0.029), high National Institutes of Health Stroke Scale (NIHSS) score at admission (P<0.001), high urea nitrogen (P=0.015), and high absolute value of neutrophil/lymphocyte (P=0.022) were the influencing factors for the short-term poor prognosis in patients with acute ischemic stroke. Multivariate logistic regression analysis showed that high NIHSS score at admission was an independent risk factor for short-term prognosis in patients with acute ischemic stroke (P=0.003). Conclusion A high NIHSS score at admission is a prognostic factor for short-term poor prognosis in patients with acute ischemic stroke, which should be paid more attention to. [ABSTRACT FROM AUTHOR]

Aiming at the inherent buffeting problem in the observer, hyperbolic tangent function with variable slope is selected as the switching function to weaken the chattering of the switching surface, and a fuzzy controller is designed to dynamically adjust the slopes of the switching function according to size of system buffeting for changing the thickness of the boundary layer, which well balances the contradiction between the buffeting and the steady- st ate error. Furthermore, a fixed sliding mode gain is easy to cause large buffeting at low speed and inaccurate estimation of position and speed at high speed. Under the condition that the observer satisfies Lyapunov stability, the sliding mode gain based on the adaptive adjustment of rotor angular speed is designed, using PLL technology to extract the rotor position and speed information improves the estimation accuracy and weakens the computational noise. The simulation and experimental results show that the improved sliding mode observer has high estimation accuracy and small buffeting, and the observation effect is still good in the wide speed range of the PMSM control system. [ABSTRACT FROM AUTHOR]

Aiming at the acid hazard of the potential acidic sulphate soil during the dredging and reclaiming process, within the harbor basin of the Timba Bay project in East Timor, the spatial distribution of the acidic soil was clarified through geological survey, investigation, and experimental analysis of acid soil in the construction area. Based on the proportion of acidbase materials in the soil, the mixing characteristics of the coral sand and potential acid soil were analyzed. It is verified that the dredging material in the coral reef area after the cutter suction process has sufficient self -neutralization ability, which effectively solves the potential acid soil disposal of the project. [ABSTRACT FROM AUTHOR]

This paper proposed an electronic voting scheme based on one-time ring signature and blockchain to solve the problems of the current e-voting system in terms of anonymity, transparency and open vote-counting. This paper introduced one-time ring signature, blockchain and stealth address technology. The one-time ring signature technology solved the problem of voter anonymity, repeated voting and public verification. The blockchain technology could ensure the openness and transparency of the e-voting system. The one-time ring signature technology could ensure no one or institution could obtain the voting intermediate result before the voting ends. In order to improve the efficiency of vote-counting,it used the method of key sharing to improve the vote-counting algorithm. Through security and performance analysis, the scheme conforms to the basic security standards of an electronic voting system. [ABSTRACT FROM AUTHOR]

The recommendation system needs to utilize a large amount of user data, which may expose the user 's preferences and pose a huge challenge to the privacy concerns. To ensure the accuracy of recommendation and user privacy, this paper proposed a matrix factorization recommendation model combining differential privacy and tag information. Firstly, the model added the tag information to the process of calculating item similarity, then integrated it into the recommendation model to improve the recommendation accuracy . Finally, this paper solved the model optimal value by the stochastic gradient descent method. For protecting use rs from privacy threats, the proposed approach divided Laplace noise into two parts, which were added to the process of item similarity and gradient solution respectively, so that the whole recommendation process satisfied the differential privacy. It verified the validity of the algorithm on a real data set. Experimental results show that the proposed method has high recommendation accuracy while protecting users' privacy. [ABSTRACT FROM AUTHOR]

Aiming at the data release and weight sequence attacks of weighted social networks, this paper proposed a weighting anonymous method based on node segmentation to realize the privacy protection of network structure, side weight and weight sequence. Based on the concept of edge space of the graph, this paper constructed the vector set model of the weighted social network by using the idea of node clustering segmentation, reallocated the weight by using the center of the interval, adjusted the weight by the distance between the group diameter and the relative distance of the node sequence, used the weighted Euclidean distance to construct the candidate vector set, and selected the vector from the candidate vector set to realize the social network.This method guaranteed the structural characteristics needed by the social network analysis, the validity of the published data and the effective protection of the weight sequence attacks under the premise of ensuring the privacy and security. [ABSTRACT FROM AUTHOR]

In traditional trajectory similarity calculation based on the Euclidean distance metric function, position of each point in the trajectory are required to have a corresponding point. The existence of noises could lead to track a larger distance deviation, reduce the trajectory similarity, increase trajectory information loss. In order to solve this problem, this paper designed LCSS-TA( longest common subsequences trajectory anonymity) algorithm combining with LCSS( longest common subsequences ) distance function and (k，δ) -anonymity model. The algorithm could decrease the greater distance of the noises might to lead by mapping the distance between trajectory locations points to 0 or 1. In synthetic data set and data set with noise, the experiment results show that the algorithm can reduce noises interference and decrease the trajectory information loss on the basis of meeting with A-anonymity privacy protection. [ABSTRACT FROM AUTHOR]

Objective To investigate the incidence of preterm delivery, low birth weight low birth weight (LBW), and small for gestational age (SGA) in pregnant women with hepatitis B virus (HBV) infection in Hunan Province and to explore the related factors. Methods The pregnant women with HBV infection who delivered from January to December, 2021 in various midwifery institutions in Hunan Province and reported to the communication system of mother-to-child transmission of hepatitis B were investigated. Their demographic characteristics, pregnancy, hepatitis B virus-related detection, and treatment were analyzed. The incidences of preterm delivery, LBW, and SGA were calculated respectively. Multivariate logistic regression was used to analyze the influencing factors. Results A total of 28 100 pregnant women with HBV infection were included, with a premature delivery rate of 6.8% (1 899/28 100), LBW rate of 4.4% (1 224/28 100), and SGA rate of 6.9% (1 931/28 100). Risk factors for preterm delivery in pregnant women with HBV infection included maternal age of 30 to 34 years and 3 35 years (compared with 25 to 29 years old), gestational age of the first antenatal examination 3 28 weeks (compared with 1 to 12 weeks), and antiviral therapy during pregnancy. The adjusted odds ratios (aOR) were 1.40 (95%CI: 1.23-1.60》 1.97 (95%CI: 1.70-2.28), 1.15 (95%CI: 1.03-1.28), and 1.36 (95%CI: 1.16-1.59), respectively. Maternal age < 20 years old, 30 to 34 years old, and 3 35 years old, and antiviral therapy during pregnancy were risk factors for LBW, and their aOR values were 1.75 (95%CI: 1.08-3.16), 132 (95%CI: 1,13-1.54) and 1.88 (95%CI: 1.57-2.25): 135 (95%CI: 1.12-1.63), respectively. Maternal age < 20 years old, 20 to 24 years old, and antiviral therapy during pregnancy were risk factors for SGA, and their aOR values were 1.92 (95%CZ: 1.24-2.97) and 134 (95%CI: 1.14-1.56), and 1.26 (95%CI: 1.07-1.48), respectively. Birth experience was a common protective factor for preterm delivery, LBW, and SGA, and their aOR values were 0.75 (95%CI: 0.67-0.85), 0.68 (95%CI: 0.59-0.78), and 0.82 (95%CI: 0.73-0,92), respectively. Conclusion The incidence of preterm delivery, LBW\and SGA in pregnant women with HBV infection in Hunan Province is not high, and it is affected by maternal age, parity, the time of the first antenatal examination, and antiviral therapy during pregnancy. [ABSTRACT FROM AUTHOR]

Users followee recommendation plays an important role in information sharing over microblogging platforms. The majority existing followee recommendation schemes adopt either content or background information relevance to measure the user distance, and most use a single factor for followee ranking, there is no classification for user groups, suffering poor performance. Thus this paper proposed a novel followee recommendation algorithm RTLR for non-celebrity that took into user the information sources of both followee relationship and interaction behavior, and established logistic regression model combined with multi-factors. It conducted experiments on real-world datasets collected from Sina Weibo, the largest microblogging system in China. The results demonstrate that the novel scheme effectively improves the accuracy of followee recommendation. [ABSTRACT FROM AUTHOR]

The outlet flow fields of the double-stage swirler with different Venturi length are measured with particle image velocimetry (PIV) and the effect of Venturi length on outlet flow fields is investigated and discussed. The downstream flow field characteristics of swirler are displayed, and the distributions of axial velocity and radial velocity are gained. The results indicated that the radial movement of Vortex core away from center line results in the increase of radial distance from 22.2 mm, to 29.2 mm, and the area of central circulation zone becomes larger with the increase of Venturi length. The characteristics of axial velocity and radial velocity are in favour of combustion organization. [ABSTRACT FROM AUTHOR]

Objective To explore the prevalence of osteoporosis and related factors after treatment of breast cancer. Methods Clinical data of 147 patients with breast cancer after treatment and menopause were collected and analyzed. Bone mineral density(BMD) of the lumbar spine, the left femoral neck, and total hip was detected using dual-energy X-ray absorptiometry. Breast cancer receptors(ER, PR,HER-2), age, BMI,menopause time, postoperative time,and treatment method were analyzed.Results The prevalence of osteoporosis after treatment in 147 patients with breast cancer was 40. 8%. Univariate analysis showed that age, BMI, menopause time, treatment(endocrine therapy + chemotherapy),postoperative time were significantly correlated with the decrease of BMD(P<0.05). Multivariate logistic regression analysis showed that age, BMI and postoperative time were the main influencing factors of BMD reduction(P<0. 05). Conclusion The prevalence of osteoporosis is high in breast cancer patients. Many factors in breast cancer treatment can reduce BMD. [ABSTRACT FROM AUTHOR]

Objective: To investigate related risk factors of allergic purpura complicated with alimentary tract hemorrhage in children. Methods: The clinical data of 80 cases of allergic purpura in newly diagnosed children from September 2013 to June 2016 who hospitalized in the pediatrician of Wuhan Union Hospital were retrospectively analyzed. According to complication with alimentary tract hemorrhage, these cases were divided into two groups: 11 cases of alimentary tract hemorrhage group and 69 cases of non-alimentary tract hemorrhage group. The age, region, sex, onset season, the distribution of purpura, the combination of purpura nephritis, C-reactive protein, erythrocyte sedimentation rate, blood routine, biochemistry of were compared between two groups. Results: Compared with non-alimentary tract hemorrhage group, the levels of serum high-sensitivity C-reactive protein (hsCRP) and serum calcium (Ca) were significantly different in alimentary tract hemorrhage group (P <0.05). There was no significant difference in the incidence of purpura nephritis between these two groups. The proportion of purpura nephritis in alimentary tract hemorrhage group was 45.5% which was obviously higher than 21.7 % in non-alimentary tract hemorrhage group. Conclusions: Summer and winter season, high levels of serum CRP, and low serum Ca2+ are risk factors of allergic purpura complicated with alimentary tract hemorrhage in children. [ABSTRACT FROM AUTHOR]

Objective: To explore the effect and mechanism of AMPK on apoptosis of alveolar epithelial cells induced by endoplasmic reticulum stress in COPD rats. Methods: the rats were divided into three groups: control group, model group, AICAR intervention group, establishment of rat model of chronic obstructive pulmonary disease by smoking smoke inhalation and intratracheal instillation of lipopolysaccharide. The HE staining of rat lung tissue pathological observation, immunohistochemical detection of p-AMPK /AMPK, western blot the expression of Caspase-3, ORP 150,and CHOP. Apoptosis were detected by TUNEL method. Results: the HE staining showed that the model group of pulmonary bullae formation, inflammatory cell infiltration, inflammatory ceils in AICAR group was lower than that of model group. Compared with the normal control group, immunohistochemistry and Western blot showed that p-AMPK/AMPK and ORP150 protein expression decreased in the model group,the difference was statistically significant (P＜0.05), and AICAR in the intervention group p-AMPK/AMPK and ORP150 protein expression were significantly increased compared with the model group,the difference was statistically significant (P＜0.05). Endoplasmic reticulum stress related apoptosis The expression of CHOP and caspase-3 apoptosis index increased significantly in the model group, there was significant difference compared with normal group (P＜0.05), while in group AICAR, apoptosis index down significantly compared with the model group. Conclusion: AMPK can protect alveolar epithelial cells from cigarette smoke induced endoplasmic reticulum stress and apoptosis, it was possible to achieve its protective effect the increase of ORP150. [ABSTRACT FROM AUTHOR]