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Objective To investigate the demands of clinical teaching and perception of the theoretical knowledge and clinical practice among nursing undergraduates at school, and provide reference for establishment of a systematic teaching management system and improve the quality of clinical teaching. Methods Totally 161nursing undergraduates at school were recruited by a convenience sampling method, and an open-ended questionnaire survey was conducted to investigate the nursing undergraduates’ demands of clinical teaching. Results The top-ranked demand for clinical teaching was the combination of theoretic knowledge and clinical practice (91. 93%), followed by the diversified teaching methods including video-assisted and real case teaching (85. 71%) and developing students' interest in clinical work(81. 99%). Most of students were satisfied with clinical teaching. Conclusion Clinical teachers should help students build clinical thinking ability by adopting the teaching method combining theory with practice. Clinical teachers should help students build conference and establish identity and self-worth in clinical practice. (目的 调查在校本科护理学生对临床带教老师的需求, 通过了解学生的理论知识与临床实践认知, 为建立系统、完善的教学管理体系, 不断探索完善临床护理实践与理论知识的紧密结合, 从而为提高临床护理教学质量提供参考。方法 采用便利抽样法对某高校161例在校本科护理学生进行临床教学需求问卷调查。结果 在校生护生对“应将书本理论与临床实操练习相结合”的需求最高(91. 93%), 其次为“教学多样化, 如视频、真实案例等教学”(85. 71%)和“教学过程中应培养学生对临床工作的兴趣”(81. 99%)。满意度调查显示, 156(96. 89%)例在校护生对教学满意。结论 在进行临床教学时, 教师可以通过现场理论与实操教学相结合的方式, 让学生建立自己的临床思维, 老师多分享临床经验, 多鼓励学生, 在潜移默化中帮助学生建立自信心, 帮助护理实习生在临床工作中找到自我价值, 从而提高护理教学质量。)

Objective To understand the current situation of research level and development ability of ICU specialist nurses in Guangxi, China, and to provide a reference basis for further improving the use and training of ICU specialist nurses. Methods A cross-sectional survey was conducted using a self-made structured questionnaire on the specialist nurses who obtained the ICU specialist nurse certification in Guangxi from 2010 to 2022. Results A total of 192 ICU specialist nurses were surveyed, 122 (63. 54%) had published papers, 45 (23. 44%) were the leading researcher of the project, 77 (40. 10%) had obtained patents; 51 (26. 56%) had participated in consultations, and 133 (69. 27%) had obtained specialist nurse certificates and then attended continuing education training. There were statistical differences in scientific achievements, participation in consultation and continuing education among specialist nurses with different titles, positions and working ages (P

Objective To investigate the effect and safety of Chinese herbal medicine Shuanghuangdan dressing combined with silver ion dressing change in improving the healing of diabetic foot wounds. Methods Totally 45 patients with diabetic foot wounds were randomly divided into three groups: Shuanghuangdan group (n=15), silver ion group(n=15) and combined treatment group (n=15). Based on the symptomatic treatment, dressing change with different dressing materials was performed. The Traditional Chinese Medicine (TCM) syndrome integral and wound healing condition were evaluated and compared between three groups. Results The combined treatment group demonstrated the smallest wound remaining after a four-week intervention, and there was a significant different between combined treatment group and Shuanghuangdan group in wound remaining(P＜0. 05). The VEGF level in the combined treatment group was higher than that in the Shuanghuangdan group and silver ion group, respectively (P＜0. 05). The TCM syndrome integral in the combined treatment group was lower than that in the Shuanghuangdan group and silver ion group, respectively (P＜0. 05). Conclusion By promoting growth of granulation tissue and blood capillary, Chinese herbal medicine dressing combined with silver ion dressing change shows a positive effect in relief of inflammation and healing of diabetic foot wounds. It is a safe and effective treatment for patients with diabetic foot wounds (目的 观察中药制剂双黄丹敷料、银离子敷料联合换药促进糖尿病足创面愈合的临床疗效, 评价其有效性和安全性。方法 选择2021年3月—9月在贵州中医药大学第一附属医院就诊的糖尿病足患者45例, 按随机数字表法分组分为双黄丹组、银离子组和双黄丹联合银离子组(联合组), 各15例。在常规对症治疗的基础上, 三组分别给予自制中药双黄丹敷料换药、银离子敷料换药和中药双黄丹联合银离子敷料换药。比较三组中医证候积分, 评估创面愈合情况。结果 治疗后, 联合治疗组创面面积最低, 与双黄丹组比较, 差异有统计学意义(P＜0. 05)。VEGF水平联合治疗组高于双黄丹组和银离子组, 中医证候积分联合治疗组低于双黄丹组和银离子组, 差异有统计学意义(P＜0. 05)。结论 中药制剂双黄丹敷料联合银离子敷料换药能明显减轻患者的炎症反应, 促进肉芽组织和新生毛细血管生长, 促进伤口创面愈合, 且创面愈合效果明显优于单纯双黄丹敷料或银离子敷料换药。)

Copyright of Journal of Aesthetic Education / Meiyu Xuekan is the property of Hangzhou Normal University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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林蛙属（Rana）物种是一类具有鼓膜和背侧褶皱，脚趾有蹼，颞面黑色，非繁殖期在山林生活的棕色蛙类。生活在北方（高纬度或高海拔）的林蛙具有耐冻性，能够忍受结冰环境而不死亡。研究表明：林蛙在低温胁迫下的存活得益于其冷冻保护系统，葡萄糖和尿素是2种主要的冷冻保护剂。进入秋季，林蛙通过蛋白质分解和脂质代谢增加体内糖原储备，遭遇低温后通过调节糖酵解和糖异生反应满足其生存的需要，尿素循环和转运相关蛋白也受到生化调节。

Copyright of Acta Sedimentologica Sinica is the property of Acta Sedimentologica Sinica Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Diagnosis & Therapy on Dermato-venereology is the property of Dermatology Hospital of Southern Medical University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Functional Polymers is the property of Journal of Functional Polymers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Surfactant Detergent & Cosmetics (2097-2806) is the property of China Surfactant Detergent & Cosmetics Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Plastics Science & Technology / Suliao Ke-Ji is the property of Plastics Science & Technology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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目的 观察益生菌联合抗氧化剂左卡尼汀口服治疗肥胖男性精子DNA碎片化率（DFI）异常的临床效果， 并探讨其可能的机制。方法 选取精子DFI异常的肥胖男性179例，按照随机数字表法分为对照组90例、观察组89 例。对照组仅口服左卡尼汀，观察组口服左卡尼汀联合益生菌地衣芽孢杆菌活菌胶囊，治疗3个月。记录两组治疗 后的临床疗效，比较其治疗前后精子密度、正常形态率、DFI以及血清人连蛋白（Zonulin）、脂多糖结合蛋白（LBP）、精 液 8-羟基脱氧鸟苷（8OHdG）水平。结果 观察组治疗后显效 31 例、有效 35 例、无效 23 例，总有效率 74. 16%（66/ 89），对照组分别为 15、28、47 例及 47. 78%（43/90）；观察组总有效率高于对照组（P<0. 05）。治疗前后两组精子密 度、正常形态率比较差异均无统计学意义（P均>0. 05）；与治疗前比较，治疗后两组 DFI均降低，且观察组降低更明 显（P 均<0. 05）。治疗后观察组血清 Zonulin、LBP 及精液 8OHdG 水平均低于同组治疗前及对照组治疗后（P 均<0. 05），治疗前后对照组上述指标无明显变化（P均>0. 05）。结论 口服益生菌联合左卡尼汀可有效降低肥胖男 性的精子DNA碎片化率，其机制可能与减轻肥胖诱发肠道细菌易位而引起的氧化应激、炎症反应有关。 [ABSTRACT FROM AUTHOR]

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Applied Ecology / Yingyong Shengtai Xuebao is the property of Chinese Journal of Applied Ecology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Engineering Science Research & Application is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Modern Food Science & Technology is the property of Editorial Office of Modern Food Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Chinese Institute of Food Science & Technology / Zhongguo Shipin Xuebao is the property of Journal of Chinese Institute of Food Science & Technology Periodical Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Capital Normal University (Natural Science Edition) is the property of Journal of Capital Normal University (Natural Science Edition) Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In recent years, polyethylene terephthalate (PET) based Ligament Advanced Reinforcement System(LARS) artificial ligaments have become popular in anterior cruciate ligament (ACL) reconstruction. However, due to its poor biological activity and high hydrophobicity, its application is limited to clinical uses. In order to improve the biological activity of materials and enhance the tendon-bone healing effect, oxygen plasma was used to introduce hydroxyl groups on the surface of PET. It has been found that the surface physiochemical treatment and immobilization of bioactive molecules have great effects on the bioactivity improvement of the inert surfaces. Therefore, bone morphogenetic proteins (rhBMP-2) with typical indicator and fibronectin (Fn) for enhancing the binding capacity of rhBMP-2 molecules were chosen as modifying molecules. The functional molecules such as epigallocatechin-3-gallate (EGCG) were coated on the PET surface first. There are six ortho phenolic hydroxyl groups in the molecular structure of EGCG. Fn molecules were then easily immobilized on the EGCG-PET surfaces. Since each subunit of Fn had a high-affinity binding site for rhBMP-2, rhBMP-2 molecules are biological anchored on the surface through long-chained Fn, which simulates the biomimetic design in the extracellular matrix. Thus, such molecules EGCG, Fn, and rhBMP-2 are sequentially immobilized on the PET surfaces. The nanocoating of rhBMP-2/EGCG/Fn is assembled to further enhance the loading efficiency of rhBMP-2 and control the release of rhBMP-2. Therefore, the surface-modified B/E-Fn-PET exhibits excellent cell compatibility. Moreover, effective loading, activity maintaining, and controlled release of rhBMP-2 give the implant surface high osteoinduction and better osteogenesis. Predictably, the integrated influences of these factors will provide technical support for designing the insert implantable surface with high bioactivities. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Growth hormone has been proven to promote the proliferation and bone differentiation of non-dental mesenchymal stem cells, but the biological effect on human periodontal ligament stem cells is still unclear. OBJECTIVE: To explore the effect of human growth hormone on the proliferation and osteogenic differentiation of human periodontal ligament stem cells. METHODS: The α-MEM complete medium containing 0 (control group), 10, 100, 200 μg/L human growth hormone was added to the third generation of human periodontal ligament stem cells. CCK-8 assay was used to detect cell proliferation at 1, 3, 5, and 7 days. The osteoinductive fluids containing 0 (control group), 10, 100, 200 μg/L human growth hormone was added to the third generation of human periodontal ligament stem cells. At 7 days, real-time PCR and western blot assay were used to detect the gene and protein expression of the bone differentiation-related factors opn and runx2. At 14 days, Alizarin Red staining and Alizarin Red semi-quantitative detection were used to analyze the mineralization of human periodontal ligament stem cells in the late stage of osteogenic formation. RESULTS AND CONCLUSION: The cell proliferation of 100 and 200 μg/L groups was significantly better than that of the control group (P < 0.05). The gene and protein expression of opn and runx2 was higher in the 100 and 200 μg/L groups than that in the control group (P < 0.05). The mineralization of human periodontal ligament stem cells in the 100 and 200 μg/L groups was better than that of the control group (P < 0.05). Results confirm that in vitro experiments, human growth hormone at concentrations of 100 and 200 μg/L can promote the proliferation and osteogenic differentiation of human periodontal ligament stem cells. [ABSTRACT FROM AUTHOR]

糖尿病足病情发展迅速,且致残、致死率高，其治疗需要及时地多学科综合治疗和转诊。 目前我国就诊转诊流程繁琐，医疗资源配置不均衡且均在线下开展，同时宙于大多数足溃疡患者都伴 有行动不便，这些原因导致糖尿病足患者不能及时得到规范化诊疗,甚至因为延误诊疗造成严重后 果。医联体的出现与发展为患者的就诊转诊提供了绿色通道，人工智能及智慧医疗的发展也进一步 促进了医学的发展。在社会、临床需求及政策驱动下，我们基于人工智能技术,构建了集糖尿病足分 级评估、综合会诊、规范化治疗为一体的"掌上益足"智能诊疗平台,并实现在医联体内的推广和应用。 现对智能平台进行介绍，以期为智慧化医疗建设提供一定的理论支撑和经验借鉴. [ABSTRACT FROM AUTHOR]

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Copyright of Journal of Modern Laboratory Medicine is the property of Journal of Modern Laboratory Medicine Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Agriculturae Zhejiangensis is the property of Acta Agriculturae Zhejiangensis Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Shenyang Agricultural University is the property of Journal of Shenyang Agricultural University Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Diabetes Mellitus is the property of Chinese Journal of Diabetes Mellitus and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Diabetes Mellitus is the property of Chinese Journal of Diabetes Mellitus and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Agriculturae Zhejiangensis is the property of Acta Agriculturae Zhejiangensis Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)