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Copyright of Journal of Ordnance Equipment Engineering is the property of Chongqing University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Petroleum Refinery Engineering is the property of Petroleum Refinery Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Petroleum Refinery Engineering is the property of Petroleum Refinery Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Petroleum Refinery Engineering is the property of Petroleum Refinery Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的 研究硼替佐米联合环磷酰胺、地塞米松方案 (VCD 方案)对初发多发性骨髓瘤合并肾功 能不全的化疗效果。方法 选取该院2018年1月至2020年10月收治的11例初发多发性骨髓瘤合并肾功能 不全患者作为研究对象, 采用 VCD 方案进行化疗。具体方案为:硼替佐米1.3 mg/m² (第1、4、8、11天),环磷 酰胺 500 mg/m² (第1、8、15、22天),地塞米松 20 mg (第1~2、8~9、15~16、22~23天)。观察化疗后肾功能恢 复情况及基础病疗效、相关不良反应,评估其安全性。结果 11例患者经治疗后多发性骨髓瘤总缓解率为 81.8%。化疗前肾功能指标血肌酐为 (498.55±107.06) μmol/L, 化疗后为 (193.36±51.45) μmol/L,差异有统 计学意义 (P <0.05), 肾功能不全总缓解率为 90.9%。不良反应主要为化疗后骨髓抑制继发白细胞、血小板下 降,主要为3级以下血液学毒性;外周神经损伤以1~2级为主,未影响化疗的执行。结论 VCD 方案对合并肾 功能不全初发多发性骨髓瘤具有良好疗效,可实现肾功能的逆转恢复,不良反应及不良反应相对较轻,可作为 多发性骨髓瘤合并肾功能不全治疗的一线选择。 [ABSTRACT FROM AUTHOR]

Copyright of Journal of Vibration Engineering is the property of Nanjing University of Aeronautics & Astronautics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)