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血管性认知障碍患者往往伴有睡眠障碍，睡眠的紊乱进一步降低了患者的生活质量，增加了其脑血管事件的风险，也加重了照料者的负担。有效治疗患者的睡眠障碍不仅可以改善其生活质量，对患者的认知及功能康复也有积极影响。本文对血管性认知障碍患者常见的睡眠紊乱进行综述，着重阐述了睡眠障碍非药物治疗方面的研究成果，并对这些治疗方法未来的研究方向以及在血管性认知障碍患者中的应用前景进行了探讨。 Abstract: Patients of vascular cognitive impairment often suffered from all kinds of sleep problems, which further reduced their quality of life, improved risk of cerebrovascular events and increased their caregiver’s burden. Effective treatment of sleep disorders can not only improve the quality of life of patients, but also have positive effects on the cognitive and functional rehabilitation of patients. In this article, we reviewed the common sleep problems in patients of vascular cognitive impairment, elaborated on the present research results of non-pharmacological treatments to these problems, and discussed the future research fields and application prospects of non-pharmacological therapy for sleep disturbance of vascular cognitive impairment patients.

褪黑素具有显著抗衰老作用,其主要机制包括自由基清除和线粒体保护，褪黑素水平的下降可能是人体衰老的表现。此外，研究证实褪黑素具有降脂、降压和减重作用，可预防和延缓动脉粥样硬化进展，改善脑缺血再灌注损伤，在缺血性卒中领域具有良好的应用前景。本文对褪黑素抗衰老、预防卒中相关危险因素和改善卒中预后等方面的作用机制和应用前景进行总结。 Abstract: Melatonin has significant anti-aging effect, and the main action mechanisms includes free radical scavenging and mitochondrial protection. The decline of melatonin level may be the manifestation of human aging. In addition, it has been confirmed that melatonin has the effect of lipid-lowering, antihypertension and weight-loss, which can prevent and delay the progression of atherosclerosis, and reduce ischemia-reperfusion injury, so melatonin has a good application prospect in the field of ischemic stroke. This article summarized the mechanism and application prospect of melatonin in anti-aging, preventing stroke related risk factors and improving stroke prognosis.

Copyright of Chinese Mental Health Journal / Zhongguo Xinli Weisheng Zazhi is the property of Chinese Mental Health Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

为了对紫苏籽压榨制油前热处理方式的选取提供参考数据，对紫苏籽进行不同程度的红外或微波热处理，根据热处理后紫苏籽的水分含量分为低、中、高3组，随后进行压榨制油，测定了经不同热处理得到的紫苏籽油的相关理化指标、脂肪酸组成、微量活性成分含量，评估了不同紫苏籽油的DPPH自由基清除率和氧化稳定性。结果表明：两种热处理方式对紫苏籽油脂肪酸组成及含量无显著影响（p＞005）；与未经处理的紫苏籽油相比，经微波热处理的紫苏籽油酸值降低，红外热处理的紫苏籽油过氧化值降低，经过微波和红外热处理的紫苏籽的出油率，油脂的黄酮含量、DPPH自由基清除率和氧化稳定性显著增加（p＜0.05）；随着红外和微波热处理程度的加深，紫苏籽油中生育酚含量逐渐降低，多酚含量先降低后升高（红外热处理）和先升高后降低（微波热处理）。综上，选取合适的热处理方式及条件可以获得较高品质的紫苏籽油。 In order to provide reference data on the selection of heat-treatment ways for perilla seed prior to pressing for oil, perilla seed were subjected to different degrees of infrared or microwave heat-treatment, and were classified into three groups (low, medium and high)according to the moisture content of perilla seed after heat-treatment. The oil was pressed, and the related physicochemical indexes, fatty acid composition, trace active components, DPPH· scavenging rate and oxidation stability of perilla seed oil obtained by different heat-treatment were evaluated. The results showed that the two heat treatments had no significant effect on the fatty acid composition and content of perilla seed oil (p＞0.05). Compared with untreated perilla seed oil, the yield, flavonoid content, DPPH·scavenging rate and oxidation stability of perilla seed oil after microwave and infrared heat-treatment significantly increased (p＜0.05), the acid value of perilla seed oil obtained by microwave treatment and peroxide value of the oil obtained by infrared treatment decreased. The tocopherol content of perilla seed oil gradually decreased with the deepening of infrared and microwave heat-treatment, and the polyphenols content first decreased and then increased of infrared treatment while it was opposite of microwave treatment. By selecting the appropriate heat treatment method and conditions, the perilla seed with higher quality can be obtained.

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Landscape Architecture (1673-1530) is the property of Beijing Landscape Architecture Journal Periodical Office Co., Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agro-Environment Science is the property of Journal of Agro-Environment Science Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Writing / Xiezuo is the property of Writing Magazine Agency, Wuhan University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Taiwan Journal of Publich Health / Taiwan Gong Gong Wei Sheng Za Zhi is the property of Taiwan Public Health Association and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To assess the value of intracranial time-of-flight magnetic resonance angiography (MRA) based on spiral imaging technology (MRAspiral) compared to compressed sensing (CS) reconstruction (MRACS). Methods From 29 May 2021 to 11 June 2022, brain MRA of 49 patients with suspected cerebrovascular disease was prospectively analyzed. MRA sequences with CS factor of 4 (MRACS4) and MRAspiral (the acquisition window τ is 4, 6, 8, 12) were acquired. The regions of interest were placed in the proximal and distal segments of the anterior cerebral artery, middle cerebral artery, and posterior cerebral artery (PCA) to calculate the contrast ratio (CR) with the corpus callosum as the background on both sequences. Qualitative analysis of image quality and diagnostic feasibility were performed independently by two experienced radiologists. One-way repeated measures ANOVA analysis was used to compare the differences in CR values and Friedman test was used to evaluate the differences in qualitative analysis. Results The CR value in the distal PCA (2.61±1.09) of MRAτ6 was significantly lower (P=0.014) than that of MRACS4 (3.16±1.62). The CR values of the other MRAspiral images (MRτ4: 2.73 ±1.45, MRAτ8: 2.78±1.28, MRAτ12: 2.64 ±1.43) were not significantly different from those of MRACS4 (P>0.05). The CR values in the MRAτ4 (4.78±0.41), MRAτ6 (4.77±0.42) and MRAτ8 (4.55±0.52) were significantly better than MRACS4 in distal vascular visualization (P<0.005). MRACS4 showed better performance than MRAspiral in proximal vessels (P>0.005). Conclusion MRAspiral is superior to MRACS in displaying distal intracranial vessels, allowing for a better assessment of the degree of intracranial vascular stenosis. MRAτ8 can reduce acquisition time while ensuring image quality. [ABSTRACT FROM AUTHOR]

Copyright of Traditional Chinese Drug Research & Clinical Pharmacology is the property of Traditional Chinese Drug Research & Clinical Pharmacology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Electronic Communication & Computer Science is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Innate and adaptive immune responses initiated by infection depend on recognition and control of pathogens by macrophages, dendritic cells, T cells and so on. Notch signaling pathway is a highly conserved pathway, which is activated by interaction of receptors and ligands, thus coordinating important life processes of cells. At present, it has been confirmed that Notch signaling pathway is involved in development, differentiation, maturation and activation of many kinds of immune cells, and plays an important role in infectious diseases. In this review, we mainly focus on the role of Notch signaling pathway in immune regulation during different pathogens infection and its interaction with other signaling pathways. Additionally, therapeutic methods and challenges of developing Notch signaling as a target in infectious diseases are also discussed. [ABSTRACT FROM AUTHOR]

Frequency Diverse Array (FDA) is a brand-new electronically scanned radar system. The time-range-angle three- dimensional correlation characteristics of its beampattern have broad application prospects in the fields of electronic counter- measures and security communications. One-dimensional uniform linear FDA array (ULFDA) has the problem of angle-range coupling in the transmit beampattern. To solve this problem, this paper adopts sine based on the symmetrical subarray density taper array structure. The frequency offset obtains the dot-shaped beampattern pointing control method at the target point posi- tion. In addition, we analyze the time-varying problem of the FDA pattern, and get the conclusion that the mainlobe of the density tapered array sin-FDA based on the subarray structure has a fixed direction in the angle dimension and changes in the range dimension. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Materials Engineering / Cailiao Gongcheng is the property of Journal of Materials Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

【目的】探讨前列腺体积对保留神经腹腔镜下根治性前列腺切除术（nsLRP）结果的影响，并分析其对术后控尿恢复的预测价值。【方法】回顾性分析 2004 年 1 月至 2018 年 6 月 178 例行nsLRP 术低危前列腺癌（PCa）患者的临床资料。所有患者术前控尿功能正常，年龄46~88 岁，平均66 岁；PSA 0.6~10.0 μg/L，中位值6.9 μg/L； 平均体质量指数（24±5）kg/m2。采用Spearman 相关系数分析前列腺体积与围术期资料关系，单因素与多因素Cox回归分析鉴定术后控尿功能恢复的预测因子。【结果】列腺体积增大与高龄（rs=0.370，P

Copyright of Water Conservancy & Electric Power Technology & Application is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To review the role of Piezo1 protein in macrophages in the regulation of homeostasis of iron metabolism, to summarize the latest advances in age-related bone loss (ARBL) and macrophage Piezo1, and to provide new ideas for the treatment of age-related bone loss. Methods The literature related to macrophage Piezo1 in age-related bone loss was screened in CNKI, PubMed, and other databases from the establishment to January 2023. The Chinese keywords included macrophages, mechanosensitive ion channel protein, age-related bone loss, and osteoporosis. The English keywords included macrophages, Piezo1, age-related bone loss, ARBL, and osteoporosis. Forty-two articles were finally included for the further review. Results Macrophages were involved in the regulation of iron metabolism homeostasis. High expression of Piezo1 in bone marrow macrophages led to iron overload in the body, which played an important role in the development of ARBL. Conclusion Piezo1 provides new ideas and perspectives at the molecular level for the treatment of age-related bone loss. [ABSTRACT FROM AUTHOR]

Recently, the incidence of ureteral calculi has been increased, and the treatment methods have been constantly updated. Nowadays, minimally invasive treatment has become a trend, mainly including extracorporeal shockwave lithotripsy （ESWL）, ureteroscopic lithotripsy (URL), percutaneous nephrolithotripsis (PCNL) and laparoscopic lithotripsis. Noncontrast computed tomography （NCCT）, as a common noninvasive diagnostic technique for clinical surgical diseases, has high specificity and sensitivity for the identification of ureteral calculi. In addition to definite diagnosis, the use of ureteral wall thickness （UWT） measurement to predict the matching degree of ureteral calculi treatment and prognosis has received widespread attention. Existing literature has suggested that UWT can predict the efficacy of ureteral stone incarceration and treatment plan. However, most studies are limited to the prediction of single treatment mode by UWT. In this article, literature review related to UWT was performed, aiming to provide reference for the prediction of ureteral stone incarceration and the selection of clinical treatment regimen. [ABSTRACT FROM AUTHOR]

Copyright of Telecommunications Science is the property of Beijing Xintong Media Co., Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Polymer Materials Science & Engineering is the property of Sichuan University, Polymer Research Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Inorganic Analytical Chemistry / Zhongguo Wuji Fenxi Huaxue is the property of Beijing Research Institute of Mining & Metallurgy Technology Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Heat-sensitive moxibustion is widely used in clinical treatment and basic research, but the biological characteristics of its sensitized acupoints are not completely clear. OBJECTIVE: To explore the effects of heat-sensitive moxibustion on connective tissue, calcium and terahertz wave in psoriatic rats and the relationship between them. METHODS: Animal models of psoriasis were induced by 5% imiquimod cream in Sprague-Dawley rats, and the experimental rats were randomly divided into blank group, model group and treatment groups. Except the blank group, the rats in the other groups were modeled with psoriatic lesions on the back and along the Sanjiao meridian of hand-Shaoyang. After successful modeling, the treatment group was treated with moxibustion at Waiguan acupoint at the same time every day, 40 minutes once for 7 days in total. During the treatment period, the tail temperature changed > 1 oC was considered to be the heat-sensitive moxibustion group, and the tail temperature changed ≤ 1 oC was considered to be the moxibustion group. Hematoxylin-eosin staining was used to observe the pathological changes of subcutaneous connective tissue, colorimetric method was used to detect the changes of calcium ions in subcutaneous fascia, and terahertz wave detector was used to detect the changes of mean terahertz wave voltage at Waiguan point. RESULTS AND CONCLUSION: Compared with the blank group, the pathological changes of connective tissue were obvious in the model group. Compared with the blank group and model group, the calcium ion concentration in subcutaneous fascia was significantly higher in the moxibustion group and heat-sensitive moxibustion group (P < 0.01). The calcium ion concentration in the subcutaneous fascia was significantly higher in the heat-sensitive moxibustion group than the moxibustion group (P < 0.01). On the 3rd day of treatment, the mean terahertz wave voltage values in the treatment groups were higher than those in the model group and the blank group (P < 0.01). On the 7th day, the mean terahertz wave voltage in the moxibustion group was still higher than that in the model group and the blank group (P < 0.01), while the mean terahertz wave voltage in the heat-sensitive moxibustion group was close to that in the blank group. Compared with the moxibustion group, the mean terahertz wave voltage of the heat-sensitive moxibustion group was increased significantly on the 3rd day (P < 0.01) and decreased significantly on the 7th day (P < 0.01). To conclude, during the treatment with heat-sensitive moxibustion, local calcium ions are enriched in the acupoint of psoriatic rats, and terahertz waves are also changed. There may be a close link between heat-sensitive moxibustion, calcium ions and terahertz waves to treat or improve the symptoms of psoriasis. [ABSTRACT FROM AUTHOR]

Drought is an important abiotic factor affecting the growth and yield of chrysanthemum, while ZF-HD transcription factor family plays an important role in coping with drought stress. Chrysanthemum nankingense is a model plant for studying genetic and breeding mechanism of chrysanthemum, screening its drought resistance related genes may lay a foundation for the relevant research in chrysanthemum. In this study, we established a local database and achieving local BLAST based on the C. nankingense genome, and used the Pfam database, HMMER, DNAMAN, MEGA, Tbtools, ExPASy, WoLF PSORT online sites and real-time fluorescence quantification for screening as well as bioinformatics and expression analysis of ZF-HD family genes. The results showed that a total of 19 ZF-HD gene family members were identified in the C. nankingense, divided into two subfamilies, ZHD and MIF, with the ZHD subfamily including subgroup I-VI. The tissue specific expressions of family members were temporally and spatially variable, their promoter regions were enriched with growth and development, stress and hormone-related response elements. The results of RT-qPCR showed that 19 CnZF-HD genes all responded to the drought stress and ABA treatment, and expression was induced under drought conditions. The genes CnZF-HD4, CnZF-HD9, CnZF-HD10, CnZF-HD14, CnZF-HD15 and CnZF-HD19 were also induced to be expressed in ABA treatment. Subgroup VI played an important role in regulating the drought resistance of C. nankingense. In addition, the expression of CnZF-HD1 gene was continuously up-regulated under drought conditions, thus it could be a candidate gene for drought resistance, but its sensitivity to ABA needs further study. [ABSTRACT FROM AUTHOR]

Copyright of Laser Technology is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Technology Economics is the property of Chinese Society of Technology Economics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Modern Food Science & Technology is the property of Editorial Office of Modern Food Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Stroke is the property of Chinese Journal of Stroke Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Electric Machines & Control / Dianji Yu Kongzhi Xuebao is the property of Electric Machines & Control and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Inorganic Analytical Chemistry / Zhongguo Wuji Fenxi Huaxue is the property of Beijing Research Institute of Mining & Metallurgy Technology Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Polymer Materials Science & Engineering is the property of Sichuan University, Polymer Research Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The aim is to clone and have bioinformatics analysis of GPX3 gene in Tibetan chickens, to detect its expressions in different tissues, and to identify the mRNA expressions of GPX3 interacting proteins and analyse their correlations for laying the foundation for further exploring the effect of GPX3 gene on immune function in Tibetan chickens. In this experiment, having 70-day-old healthy Tibetan chickens as study material, RT-PCR was applied to clone the CDS sequence of GPX3 gene and to perform the biological analysis. Real-time fluorescent quantitative PCR (qPCR) was used to detect the expression differences of GPX3 gene in the hearts, livers, spleens, lungs and kidneys of Tibetan chickens, and to analyze the mRNA expressions of 10 related proteins that may interact with GPX3 protein in spleen. A full length of 799 bp GPX3 gene sequence was cloned successfully, including 78 bp of 5' UTR, 660 bp of CDS, and 61 bp of 3' UTR, encoding 219 amino acids. GPX3 mRNA was expressed in 5 tissues of Tibetan chickens, and the highest in the spleen, predicting that the result of the highest expression of GPX3 in the spleen might be related to this protein immune function. GPX3 protein showed a highly and significantly positive correlation with the predicted reciprocal protein SOD2, suggesting that GPX3 might play an important role in drug resistance and reproductive regulation. A 660 bp CDS of GPX3 gene was cloned successfully in this study, predicting that it might be highly significantly and positively correlated with SOD2. This study may provide a theoretical basis for further understanding the role of the antioxidant function of GPX3 gene in the immune mechanism of Tibetan chickens. [ABSTRACT FROM AUTHOR]

Copyright of China Forestry Economy is the property of China Forestry Economy Magazine Agency and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Inorganic Chemicals Industry is the property of Editorial Office of Inorganic Chemicals Industry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Poststreptococcal reactive arthritis (PSRA) refers to reactive arthritis after Group A streptococcal (GAS) infection that does not meet the diagnostic criteria for acute rheumatic fever (ARF). It is rare in clinical practice and prone to misdiagnosis due to the lack of characteristic symptoms and signs in the early stage of PSRA. In this article， an adult male patient with PSRA was reported， showing recurrent swelling and pain on the back of the right foot and the medial malleolus. The onset process of the patient was suspected of gout. He received the treatment of reducing uric acid and relieving pain in a local hospital， which was ineffective. The patient was finally diagnosed with PSRA because of the history of pharyngitis and elevated levels of C-reactive protein and antistreptolysin O (ASO) through detection. He received long-term use of benzathine benzylpenicillin combined with anti-inflammatory and analgesic therapy. Subsequently， the condition was improved and no recurrence occurred during follow-up. The diagnosis and treatment of this case prompt that for patients with recurrent arthritis， the possibility of PSRA should be considered. Extensive attention should be paid to differential diagnosis and treatment between gout and reactive arthritis. [ABSTRACT FROM AUTHOR]

Biogenic amines are small molecular basic nitrogenous compounds w让h biological activity・ In the process of natural food fermentation and food processing, due to the influence of microbial and physical factors, it is difficult to inhibitor eliminate the formation o£ biogenic amines・ Therefore, it is of great significance to establish accurate and sensitive detection of biogenic amines in food for human health and risk avoidance・ Based on this, the types of in food were introduced, the biogenic amine detection pretreatment method mainly adopts liquid-liquid extraction, solid phase extraction method, the advantages and disadvantages of pretreatment methods and the latest progress are reviewed in detail, in order to provide a theoretical basis for the efficient analysis of biogenic amines in food. [ABSTRACT FROM AUTHOR]

Penicillium italicum is the causal agent of citrus blue mold, which is a major threat to the global citrus fruit industry. Antofine, a natural phenanthroindolizidine alkaloid, is water-soluble and exhibits a broad range of biological activities. However, whether it can inhibit P. italicum growth and the potential inhibitory mechanism remains to be elucidated. This study aimed to investigate the antifungal mechanism of antofine against P. italicum using scanning electron microscopy, transmission electron microscopy (TEM), propidium iodide staining, and tandem mass tag-labeled quantitative proteomic analysis. Antofine was found to exhibit its preeminent antifungal activity against P. italicum with a minimum inhibitory concentration of 1.56 mg/L and a minimum fungicidal concentration of 6.25 mg/L. The challenge test revealed that antofine inhibited the development of citrus blue mold during a 6-d P. italicum -infected period. Antofine acted on its potential multitargets to inhibit P. italicum growth by synergistically activating oxidative stress through accumulating excess reactive oxygen species, impairing membrane integrity, inducing membrane lipid peroxidation, and disrupting mitochondrial function, thereby disrupting the membrane system and reducing cell viability. Moreover, antofine treatment downregulated most differentially expressed proteins involved in carbon metabolism, pyruvate metabolism, and the tricarboxylic acid cycle (TCA) in P. italicum mycelia, which may explain the mitochondrial decomposition observed by TEM and the declines in ATP levels as well as the activities of TCA-related enzymes. These results indicate that antofine treatment inhibited P. italicum growth by targeting the cell membrane and mitochondria. [ABSTRACT FROM AUTHOR]

BACKGROUND: Heat-sensitive moxibustion is confirmed to be effective in the treatment of psoriasis, but the specific mechanism is still unclear. OBJECTIVE: To explore the effect of heat-sensitive moxibustion on psoriasis rats and its mechanism. METHODS: Sixty healthy Sprague-Dawley rats aged 8-10 weeks were randomly divided into blank control group (n=15), model group (n=15), and treatment group (n=30). Except for the blank group, animal models of psoriatic lesions were made on the back and the skin along the Sanjiao meridian of hand-Shaoyang. After successful modeling, the treatment group was treated with heat-sensitive moxibustion at Waiguan point of the Sanjiao meridian of hand-Shaoyang at the same time every day, 40 minutes once, for 7 continuous days. The treatment group was subdivided into heat-sensitive moxibustion group (n=15) and moxibustion group (n=15) according to the changes of tail temperature in the daily moxibustion process. After treatment, the rats in each group were scored by the psoriasis area and severity index (PASI), and after treatment, the protein expressions of JAK3, STAT3, p-JAK3, and p-STAT3 in the skin and fascia of Waiguan point were detected by western blot assay. RESULTS AND CONCLUSION: The PASI scores in the moxibustion group and heat-sensitive moxibustion group were lower than that in the model group, while the PASI score in the heat-sensitive moxibustion group was lower than that in the moxibustion group and there was no significant difference between groups. Compared with the model group, the protein expressions of p-JAK3 and p-STAT3 in the fascia of Waiguan point were significantly decreased (P < 0.05), and the protein expression of p-JAK3 in the skin of Waiguan point was also significantly reduced in the moxibustion group (P < 0.05). Compared with the model group, the protein expressions of JAK3, STAT3, p-JAK3, and p-STAT in the fascia and skin of Waiguan point were significantly decreased in the heat-sensitive moxibustion group (P < 0.05). Compared with the moxibustion group, the protein expression of STAT3 in the fascia of Waiguan point was significantly reduced in the heat-sensitive moxibustion group (P < 0.05). To conclude, both moxibustion and heat-sensitive moxibustion can improve the skin lesions of psoriatic rats and inhibit the inflammation of psoriasis. Furthermore, heat-sensitive moxibustion has a better efficacy than moxibustion, and its mechanism may be related to the inhibition of STAT3 signal pathway. [ABSTRACT FROM AUTHOR]