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BACKGROUND: The structure of nanofibers prepared by electrospinning technology is similar to that of natural tendon tissue and extracellular matrix, and has the inherent characteristics of nanofibers. OBJECTIVE: To review the structure of various electrospinning scaffolds and their application in tendon and rotator cuff tissue engineering systematically. METHODS: PubMed, CNKI, Wanfang, and Web of Science databases were searched for relevant articles published from 2000 to 2020 with the search terms of “electrospun, tendon, rotator cuff, tissue engineering” in both English and Chinese. Totally 69 articles were finally included for analysis. RESULTS AND CONCLUSION: There are various strategies in manufacturing electrospun scaffolds. Scaffolds differ from material selection, fiber composition, modification and drug loading and many other aspects. Natural and synthetic materials both have their own advantages. Hybrid electrospinning of more than two kinds of materials can produce unique properties. Although non-aligned fibers have better tensile length, aligned fibers have advantages in elastic modulus, fracture strength and biocompatibility. Nanofibrous scaffolds can also be used in drug release, and it may have a modified characteristic and improve rotator cuff and tendon healing. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)