Search

Objective To analyze the effect of fisetin against venous thrombosis in rats. Methods Seventy SD rats were randomly divided into the following groups: sham-operation group, model group, fisetin 45 mg/kg, 15 mg/kg, 5 mg/kg groups, and aspirin group (47 mg/kg). The corresponding medication was administered by gavage once a day consecutively (the sham-operation group and the model group were given 0.5% carboxymethyl cellulose sodium solution with 10 mL/kg, respectively) for 7 consecutive days. One hour after the last administration, the rats were anesthetized, the lower part of the intersection of inferior vena cava and left renal vein was ligated with silk thread (no ligation in the sham-operation group), and the abdominal wall was sutured. Two hours later, the abdominal cavity was reopened, the other venous branches 1.5 cm away from the ligation site were closed with the artery clamp, and blood was collected from the abdominal aorta. The anticoagulant ratio of 3.8% sodium citrate whole blood was 19. The venous thrombus 1 cm down from the ligation point of the intersection of inferior vena cava and left renal vein was cut and the thrombus was separated. The residual blood was dried with filter paper, weighed and recorded. Plasma was taken after anticoagulant blood centrifugation. The levels of plasma antithrombin-III (AT-III), protease C (PC), plasminogen (PLG), and plasminogen activator inhibitor (PAI-1) were detected by ELISA kits. Results Compared with the model group, the weight of thrombus in fisetin 45 mg/kg group and aspirin 47 mg/kg group decreased (P<0.01). The content of AT-III in three fisetin groups increased (all P<0.05). The content of PC in fisetin 45 mg/kg increased (P<0.05). The content of PLG and PAI-1 in fisetin 45 mg/kg group decreased (both P<0.05). Conclusion Fisetin has the effect against venous thrombosis in vivo, and the effect is related to the upregulation of AT-III and PC and the downregulation of PLG and PAI-1. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Chongqing University of Technology (Natural Science) is the property of Chongqing University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To study the effects of body surface temperature sensory block level on the maternal body temperature, labor analgesia effect, labor progress and instrument assisted delivery during epidural labor analgesia. Methods One hundred parturients with epidural labor analgesia in this hospital from May 2021 to April 2022 were randomly divided into the high level group (T6 group) and low level group (T8 group), 50 cases in each group, and 0. 075% ropivacaine + 0. 5%μg/mL sufentanil mixture liquid was used for epidural analgesia. The T6 group: the temperature level of epidural block was controlled at T6;the T8 group: the temperature level of epidural block was controlled at T8. The effect of temperature sensory block level on maternal body temperature, as well as the influences of analgesic effect, intrapartum fever, labor process time, time from rupture of membrane to delivery, oxytocin use rate and instrument midwifery rate were observed. Results The analgesic effect in the T6 group was better than that in the T8 group, but the rate of intrapartum fever and use rate of oxytocin in the T6 group were higher than those in the T8 group, and the time of labor, time from rupture of membrane to delivery in the T6 group were longer than those in the T8 group, the differences were statistically significant (P＜0. 05). There was no statistically significant difference of the instrumental midwifery rate between the two groups (P＞0. 05). Conclusion During epidural labor analgesia, the control of temperature block level at T6 is better than at T8, but which will increase the rate of intrapartum fever, prolong the duration of labor and increase the use rate of oxytocin. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Chongqing University of Technology (Natural Science) is the property of Chongqing University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Science Technology & Engineering is the property of Chinese Society of Technology Economics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Rock & Mineral Analysis is the property of Editorial Board of Rock & Mineral Analysis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Brewing is the property of China Brewing Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Rock & Mineral Analysis is the property of Editorial Board of Rock & Mineral Analysis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Oil Drilling & Production Technology / Shiyou Zuancai Gongyi is the property of Shiyou Zuancai Gongyi Bianjibu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Sepiolite is a very important non-metallic mineral, which is widely used in aviation, animal husbandry, the chemical industry, environmental protection and other fields. Sepiolite is in great demand and needs a lot of analysis and testing. However, the existing sepiolite reference materials are inadequate and do not satisfy the needs of sepiolite composition analysis. Furthermore, there are no sepiolite reference materials in China, making it necessary to develop one. OBJECTIVES: To prepare a reference material for composition analysis of sepiolite whose certified value components cover as many elements as possible. METHODS: Sepiolite samples were collected from Xiangtan, Hunan Province. The samples were subjected to primary crushing, coarse-grain sieving, inactivation, fine grinding and fine grain sieving. After passing the initial inspection, samples were bottled and numbered. Random samples were taken for homogeneity test, stability test. 24 components were selected for homogeneity and stability test. RESULTS: The results showed that the RSD of 20 components were less than 3%, and the F value of the variance test was less than the critical value of the list [F0.05（29,60）=1.65], indicating that the homogeneity of the reference material was good. During the investigation period, the contents of 24 components had no significant change, indicating that the standard material was stable. Nine laboratories cooperated with traditional chemical analysis methods and modern instrumental analysis methods to determine the value. The final values were 63 components, covering major, trace and all rare earth elements. The contents of characteristic components MgO and LOI were 18% and 8.55%, respectively. These two components form a certain ladder with the existing reference materials, which can better satisfy the requirements of sepiolite composition analysis. CONCLUSIONS: The developed sepiolite reference material can be used as the quality control standards for geological prospecting, geochemical investigation and testing of geological and mineral products, as well as for other industries to analyze similar materials. Moreover, in the process of developing the reference material, improvements and developments to the new methods will provide technical support for the subsequent development of the sepiolite reference material. [ABSTRACT FROM AUTHOR]

Copyright of Rock & Mineral Analysis is the property of Editorial Board of Rock & Mineral Analysis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Heilongjiang University of Science & Technology is the property of Journal of Heilongjiang University of Science & Technology Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Heilongjiang University of Science & Technology is the property of Journal of Heilongjiang University of Science & Technology Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Medical Equipment Journal is the property of Chinese Medical Equipment Journal Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Rock & Mineral Analysis is the property of Editorial Board of Rock & Mineral Analysis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Rock & Mineral Analysis is the property of Editorial Board of Rock & Mineral Analysis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Petroleum Machinery is the property of China Petroleum Machinery Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Rock & Mineral Analysis is the property of Editorial Board of Rock & Mineral Analysis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Rock & Mineral Analysis is the property of Editorial Board of Rock & Mineral Analysis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Petroleum Machinery is the property of China Petroleum Machinery Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Rock & Mineral Analysis is the property of Editorial Board of Rock & Mineral Analysis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Rock & Mineral Analysis is the property of Editorial Board of Rock & Mineral Analysis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Rock & Mineral Analysis is the property of Editorial Board of Rock & Mineral Analysis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To investigate the protective effects of exogenous estrogen on bone tissue in a postmenopausal osteoporosis (PMO) rat mode, as well as the effect on the expression of NFATc1. Methods：The 12 weeks Wistar rats were randomly divided into sham operation group, OVX group, and OVX+E2 group and 10 rats in each group. In the OVX+E2 group, 17β-E2 was injected subcutaneously and the other two groups were given the same volume of normal saline. After 16 weeks, the serum E2 level was determined by ELISA, the expression of NFATc1 in bone tissue were measured by RT-PCR, the bone mineral density （ＢＭＤ）, the fraction of bone tissues （ＢＶ/ＴＶ）, the thickness of the trabecular bone （Tb.Th） and number of trabecular bone （Tb.N） were measured using Micro-CT analysis. Results：The OVX+E2 group and sham operation group compared with the OVX group, the levels of BMD, BV/TV, Tb.Th, Tb.N and serum E2 were significantly increased, the level of NFATc1 were significantly decreased (P＜0.05). Conclusions：Estrogen may prevent bone loss by decreasing NFATc1 expression in OVX rats. [ABSTRACT FROM AUTHOR]

Objective: To investigate the effects of oestradiol on the Wnt signaling pathway in the middle cerebral artery occlusion (MCAO) model of ovariectomized female Wistar rats, so as to explore the protective effect of estrogen on the central nervous system. Methods：Sixty female Wistar rats aged three months were randomly and equally divided as follows: sham operation group (ｗｉｔｈｏｕｔ ｏｖａｒｉｅｃｔｏｍｙ), model group (ovariectomy), estrogentreated group [ovariectomy and estrogen replacement, 17β-estrogen, s.c. 300 μg/(ｋｇ·ｄ)]. All rats were developed the model of MCAO with the previous protocol. The brain infarction area was measured with the TTC staining. The expressions of APC and β -catenin were evaluated by immunohistochemistry and western blot. Results：The estrogen-treated group had significantly less infarct volume than the model group [(255.43±51.43) mm3 versus (490.75±93.38) mm3 , t=5.565, P=0.001]. Immunohistochemical analysis showed that model group had an increased expression of APC compared with sham operation group and estrogen -treated group (Ｐ <０.０５). The protein expression of β -catenin 24 h after MCAO in the cerebral cortex of estrogen -treated group was significantly increased compared with model group (Ｐ<０.０５), and there was no significant difference compared with sham operation group(Ｐ>０.０５). Western blotting analysis showed that the expression of APC was decreased in cortex of the estrogen-treated group, and that the expression of β-catenin was increased, when compared with the model group (Ｐ<０.０５). Conclusions：Exogenous oestradiol decreased the APC level, and activate the Wnt/β-catenin signaling pathway, in the cortex of MCAO brain damage in those ovariectomized female rats, suggesting that the hormone replacement therapy plays a protective effect in the central nervous system of brain blood supply insufficiency [ABSTRACT FROM AUTHOR]

Copyright of Journal of International Obstetrics & Gynecology is the property of TianJin Medical Information Center and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Obstetrics & Gynecology is the property of TianJin Medical Information Center and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)