1. Active phlorotannins from seven brown seaweeds commercially harvested in Brittany (France) detected by(1)H NMR and in vitro assays: temporal variation and potential valorization in cosmetic applications
- Author
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Stéphane Cérantola, Leslie Gager, Jean-François Arbona, Solène Connan, Magali Molla, Céline Couteau, Laurence Coiffard, Valérie Stiger-Pouvreau, Laboratoire des Sciences de l'Environnement Marin (LEMAR) (LEMAR), Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Brest (UBO)-Institut Universitaire Européen de la Mer (IUEM), Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Mer, molécules et santé EA 2160 (MMS), Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques, Université de Nantes (UN)-Université de Nantes (UN)-Le Mans Université (UM)-Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN), plateforme technologique RMN-RPE-SM, and Université de Brest (UBO)
- Subjects
0106 biological sciences ,antioxidant ,Monitoring ,Fucus serratus ,Alaria esculenta ,Brown algae ,antioxidant activity ,panorama ,Plant Science ,Aquatic Science ,Epigallocatechin gallate ,01 natural sciences ,Phlorotannin ,20% Panorama HCERES 2020 ,ACTI ,chemistry.chemical_compound ,biological-activities ,Himanthalia elongata ,Maceration (wine) ,sargassaceae ,14. Life underwater ,Food science ,fucus-vesiculosus ,UBO ,chemistry.chemical_classification ,algae ,biology ,010604 marine biology & hydrobiology ,ACL ,Polyphenols ,Cosmeceutical ,Seasonality ,biology.organism_classification ,NMR analysis ,chemistry ,ascophyllum-nodosum ,DISCOVERY ,total phenolic content ,nutrient availability ,seasonal-variation ,[SDE.BE]Environmental Sciences/Biodiversity and Ecology ,Fucales ,Ascophyllum ,Proceedings Paper ,010606 plant biology & botany ,b radiation - Abstract
WOS:000569919500022; This study was focused on the phenolic content and associated cosmetic activities of seven brown marine macroalgae:Alaria esculenta,Ascophyllum nodosum,Bifurcaria bifurcata,Fucus serratus,Halidrys siliquosa,Himanthalia elongata, andLaminaria ochroleuca, selected for their abundance in Brittany and their phlorotannin production. Phlorotannins were extracted by maceration followed by a liquid/liquid purification to obtain fractions enriched in phlorotannins. Seasonal and yearly variations in phenolic contents were investigated thanks to the Folin-Ciocalteu assay to find the best harvesting season for each species.H-1 nuclear magnetic resonance (NMR) was used to validate the presence of phenolic compounds and to compare the species in terms of phenolic signals, as they produce different phlorotannin molecules. Activities required for cosmetic applications (i.e., radical scavenging, antioxidant, photoprotective, and anti-aging activities) were assessed by in vitro tests. Fucales, especiallyA. nodosum,F. serratus,H. elongata, andH. siliquosa, showed higher phenolic contents than Laminariales.Temporal variations were apparent for five seaweeds with the highest phenolic content, notably in autumn. The phenolic content was high regardless of the season and antioxidant and photoprotective activities were similar to those of commercial molecules, allowing year-round algal harvesting. The anti-aging activity ofA. nodosumandF. serratusfractions was higher than the active tea flavonol, epigallocatechin gallate. These results are promising for the use of abundant marine macroalgae as a source of natural active ingredients for cosmetic applications.
- Published
- 2020
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