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Aim. A comparative analysis of mertoplasty results for treatment of uterine scar leak by different approaches.Materials and methods. A retrospective analysis of hospital records of 51 patients was made, which were divided into three groups depending on the surgical approach used: group 1 – laparotomy access, group 2 – laparoscopic access, group 3 – transvaginal access. All patients had hysteroscopic and ultrasound signs of uterine scar leak after cesarean section (thickness of the myometrium in the scar area less than 4 mm, discontinuity of the scar). One month after the surgery, all the patients were examined by an obstetrician-gynecologist, all had a control ultrasound to assess the condition of the uterine scar. To assess the reliability of differences between groups, differences were considered significant at p

Aim. To reduce incidence of mesh-related complications by comparative analysis of the results of vaginal extraperitoneal mesh-vaginopexy with use of trocar and anchoring systems.Materials and methods. A retrospective analysis of outpatient and hospital charts of 160 patients was performed, who underwent operative treatment of genital prolapse by vaginal extraperitoneal vaginopexy with Prolift, Johnson & Johnson, USA, Pelvix (Lintex, RF), Elevate (AMS, USA) and the Calistar system (Promedon, Argentina). The duration of postoperative follow-up was 3 years. In the 1st group, the patients were operated on using trocar techniques (Prolift, Pelvix). The second group consisted of patients operated on with the use of anchor technologies using the Elevate and Calistar methods. The degree of prolapse of the genitals was determined by the POP-Q system. The index of the influence of genital prolapse on the quality of life (IVQV) was assessed using a validated PD-QL questionnaire. To verify the accuracy of the hypothesis, Chi-square was used. Differences were considered valid for p

The aim of research was to analyze the histologic and histochemical condition of vaginal fascia, to compare it to biochemical markers of collagen disintegration and clinical signs of undifferentiated connective tissue dysplasia in patients with recurrent genital prolapse.The research included 107 patients with recurrent genital prolapse using clinical, phenotypical, laboratory and immunohistochemical assessment. Mean age was 52 ± 3.6 years. Clinically light form of UCTD was found in 14.9 % of patients (1a subgroup), moderate form - in 73.8 % (1b subgroup), severe form - in 11.2 % (1c subgroup).In samples of control group no signs of protein dystrophy were found, muscular fibers were structured. In samples of 1a subgroup some focal homogenized bundles of collagen fibers were found. Immunohistochemistry showed prevalence of type I collagen with focal incorporations of types III and IV.Samples of 1b subgroup showed moderate muscular proliferation. In immunohistochemistry considerable proliferation of type III and IV collagen were revealed, including vascular walls.In subgroup 1c samples showed disorderly located and irregularly stained coarse-fibered collagen. Immunohistochemistry showed type IV collagen all over the surface of samples. Increased level of hydroxyproline in serum were highly relevant to results of immunohistochemical analysis and clinical signs of genital prolapse. Complex assessment of laboratory markers, clinical signs and results of immunohistochemistry helps to verify diagnosis of UCTD.

Uterine disorders can considerably contribute to infertility. In order to overcome many different causes of female infertility a complex of diagnostic and therapeutic procedures was established. More than 100 bioactive substances influence the process of nidation. Uteroplacental relations are key factor of onset and normal course of pregnancy. The aim of current research is to evaluate prognostic value of expression of steroid hormone receptors and Ki-67 protein in pregravid endometrium of patients with positive results of in-vitro fertilization program. Research included 167 patients who underwent IVF and embryo transfer program in Base Clinic of Obstetrics and Gynecology, Krasnodar, in 2016-2017 years. Two groups were formed as follows: the 1st group was made of 72 patients who had pregnancy after IVF program and had full term delivery; the 2nd group was composed of 95 women with the negative result after IVF program. All patients had been examined according to the Ministry of Healthcare Order№ 107n “On applying assisted reproductive technologies, contraindications and limitations of their use” and had their first IVF program. The endometrial biopsy was performed on day 8-11 of menstrual period in order to conduct histological and immunohistochimical analyses. IHC showed irregular expression of steroid hormone receptors in endometrial glands and stroma and altered proliferative activity of those structures in women with unsuccessful IVF. Assessment of steroid hormone receptors expression and protein Ki-67 expression may be considered as additional prognostic criteria of success in IVF. Immunohistochemical analysis of pregravid endometrium can improve diagnosis of uterine causes of infertility.

During present research, 216 patients with external genital endometriosis were examined. Examined women had been suffering from complaints (pelvic pain, dyspareunia, psycho-emotional disorders) from 1.5 to 19 years. The influence of these methods of rehabilitation was monitored on parameters of life quality and intensity of pain before and after treatment. Therapy included use of dienogest 2 mg or ethynilestradiol 30 mсg/dienogest 2 mg with or without radonotherapy. Positive effects of all three methods were revealed. After treatment amount of women, still complaining of pelvic pain reduced to 12.0-30.6%. In comparison application of dienogest 2 mg and radon appears to be more effective.

The formulation of the topic and the related issues are determined by the main requirements concerning one of the language functions, particularly the communicative one which plays a leading role in human communication. The theory of the socio-cultural approach is based on understanding the social nature of language. The communication process involves the use of the social context forming a broad socio-cultural context of the interaction of subjects in communication, along with the cultural one. The sociolinguistic component, the embodiment of the ethnosocial linguistic culture, acts as an external and internal condition for speech activity. The article discusses the main approaches to the research of the social role of language in communication, presented by the works of famous scientists. Language as one of the main tools of human communication is inherently a social phenomenon. Its functioning is determined by such social factors as cultural norms, traditions, values of different societies. Additionally, the society itself contains differences between native speakers: their age, gender differences, social status, level of culture and education, region of residence, as well as differences in speech behavior depending on the situation and participants in communication. The sociality of the language determines the linguistic changes assimilated by society and manifested in speech. [ABSTRACT FROM AUTHOR]