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Resume Objectif L'objectif de cette etude est d'evaluer l'activite des antibiotiques vis-a-vis des souches de Streptococcus agalactiae isolees a Monastir (Tunisie). Materiel et methode Ce travail retrospectif a porte sur 300 souches de S. agalactiae isolees de differents produits pathologiques collectes a l'hopital Fattouma-Bourguiba de Monastir. L'identification a ete realisee selon les caracteres bacteriologiques usuels. Le serogroupage a ete realise grâce a des tests d'agglutination. La sensibilite aux antibiotiques a ete determinee par la technique de diffusion sur milieu gelose selon les recommandations du Comite de l'antibiogramme de la Societe francaise de microbiologie. Resultats S. agalactiae a ete isole essentiellement d'infections vaginales dans 31,3 % des cas et d'infections urinaires dans 24,7 % des cas. Toutes les souches ont ete sensibles a la penicilline G. Les resistances les plus elevees ont ete observees pour l'erythromycine (38,5 %) et la lincomycine (36,6 %). La resistance de haut niveau aux aminosides a ete de 6,5 % pour la kanamycine et de 0,6 % pour la gentamicine. Conclusion La penicilline reste l'antibiotique de choix, mais on observe de plus en plus de resistances vis-a-vis des autres antibiotiques justifiant l'etude de la sensibilite aux antibiotiques en routine des souches de S. agalactiae .

The aim of this study was to determine the susceptibility rates and patterns in P. aeruginosa strains isolated from 2002 to 2005 in a teaching Hospital of Tunisia. Susceptibility to antibiotics was assessed according to CA-SFM guidelines. During this period, 1368 strains of P. aeruginosa were identified, they were isolated mainly from pus (52.9%), respiratory samples (19.5 %), urine (10.6%), and blood cultures (5%). The percentages of resistant isolates were as follows: ticarcilline: 26.2%; ceftazidime: 21.8%; imipenem: 19.6%; gentamicin: 39.3%; amikacin: 19.2%, and ciprofloxacin: 21.6%. Nosocomial infections in P. aeruginosa are responsible for important morbidity and mortality rates, the survey of resistance to antibiotics is necessary for an efficient treatment.

The aim of this study was to determine the antimicrobial susceptibility of Streptococcus agalactiae strains in Monastir (Tunisia).This retrospective study included 300 strains of S. agalactiae from several pathological samples collected at the Monastir Fattouma Borguiba Hospital. The identification was based on conventional bacteriological features. Serogrouping was performed using agglutination tests. The susceptibility to antibiotics was studied according to the Antibiogram Committee of the French Society of Microbiology recommendations.S. agalactiae was mainly isolated from patients with vaginal infections (31.3%) and urinary tract infections (24.7%). All strains were susceptible to penicillin G. Resistance was mostly observed to erythromycin (38.5%) and lincomycin (36.6%). 6.5% were highly resistant to kanamycin and 0.6% to gentamicin.Penicillin remains the most effective antibiotic, but resistance to other antibiotics is emerging. This justifies the routine studying of antimicrobial susceptibility in S. agalactiae stains.

The aim of this study was to determine the susceptibility rates and patterns in P. aeruginosa strains isolated from 2002 to 2005 in a teaching Hospital of Tunisia. Susceptibility to antibiotics was assessed according to CA-SFM guidelines. During this period, 1368 strains of P. aeruginosa were identified, they were isolated mainly from pus (52.9%), respiratory samples (19.5 %), urine (10.6%), and blood cultures (5%). The percentages of resistant isolates were as follows: ticarcilline: 26.2%; ceftazidime: 21.8%; imipenem: 19.6%; gentamicin: 39.3%; amikacin: 19.2%, and ciprofloxacin: 21.6%. Nosocomial infections in P. aeruginosa are responsible for important morbidity and mortality rates, the survey of resistance to antibiotics is necessary for an efficient treatment.