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The interaction of an ultra-intense laser pulse with a near critical density target results in the formation of a plasma channel, a strong azimuthal magnetic field and moving vortices. An application of this is the generation of energetic and collimated ion beams via magnetic vortex acceleration. The optimized regime of magnetic vortex acceleration is becoming experimentally accessible with new high intensity laser beamlines coming online and advances made in near critical density target fabrication. The robustness of the acceleration mechanism with realistic experimental conditions is examined with three-dimensional simulations. Of particular interest is the acceleration performance with different laser temporal contrast conditions, in some cases leading to pre-expanded target profiles prior to the arrival of the main pulse. Preplasma effects on the structure of the accelerating fields are explored, including a detailed analysis of the ion beam properties and the efficiency of the process. Improved scaling laws for the magnetic vortex acceleration mechanism, including the laser focal spot size effects, are presented.

Efficiently shaping femtosecond, transverse Gaussian laser beams to flat-top beams with flat wavefronts is critical for large-scale material processing and manufacturing. Existing beam shaping devices fall short either in final beam homogeneity or efficiency. We present an approach that uses refractive optics to perform the majority of the beam shaping and then uses a fine-tune device (spatial light modulator) to refine the intensity profile. For the beam that we selected, circularly asymmetric with intensity fluctuations, our method achieved a uniformity of 0.055 within 90% of the beam area at 92% efficiency. The optimization involved an iterative beam shaping process that converged to optimum within 10 iterations.

What does feminist theory have to offer sociology? Defining feminist theory as work that problematizes the gender binary and the relations of domination that constitute and emerge from it, we explore four key aspects of feminist scholarship. We begin with work that explores gender as a structuring trope. We then turn to how gender is coconstituted with other structures of power and domination. Next, we survey how feminists have theorized the relationship between nature and the social through the body. Finally, we examine feminist epistemological claims. We conclude by demonstrating the inextricability of feminist conceptual work and feminist politics. As we move across these bodies of work, we show how they are linked with one another and suggest some of the ways in which thinking like a feminist would help sociologists better grasp the dynamics of the social worlds we study.

We show that multi-GeV laser wakefield electron accelerators in meter-scale, low density hydrodynamic plasma waveguides operate in a new nonlinear propagation regime dominated by sustained beating of lowest order modes of the ponderomotively modified channel; this occurs whether or not the injected pulse is linearly matched to the guide. For a continuously doped gas jet, this emergent mode beating effect leads to axially modulated enhancement of ionization injection and a multi-GeV energy spectrum of multiple quasimonoenergetic peaks; the same process in a locally doped jet produces single multi-GeV peaks with

Introduction Despite decades of research, programming and investment into improving sexual and reproductive health and rights outcomes, there has been inadequate attention paid to sexual activity. (1,2) Information, education and [...], Objective To refine a standard questionnaire on sexual practices, experiences and health-related outcomes to improve its cross-cultural applicability and interpretability. We aimed to explore participants' willingness and ability to answer the draft questionnaire items, and determine whether items were interpreted as intended across diverse geographic and cultural environments. Methods We conducted cognitive interviews (n = 645) in three iterative waves of data collection across 19 countries during March 2022-March 2023, with participants of diverse sex, gender, age and geography. Interviewers used a semi-structured field guide to elicit narratives from participants about their questionnaire item interpretation and response processes. Local study teams completed data analysis frameworks, and we conducted joint analysis meetings between data collection waves to identify question failures. Findings Overall, we observed that participants were willing to respond to even the most sensitive questionnaire items on sexual biography and practices. We identified issues with the original questionnaire that (i) affected the willingness (acceptability) and ability (knowledge barriers) of participants to respond fully; and/or (ii) prevented participants from interpreting the questions as intended, including poor wording (source question error), cultural portability and very rarely translation error. Our revisions included adjusting item order and wording, adding preambles and implementation guidance, and removing items with limited cultural portability. Conclusion We have demonstrated that a questionnaire exploring sexual practices, experiences and health-related outcomes can be comprehensible and acceptable by the general population in diverse global contexts, and have highlighted the importance of rigorous processes for the translation and cognitive testing of such a questionnaire. [phrase omitted] [phrase omitted] Objectif Adapter un questionnaire standard sur les pratiques et experiences sexuelles ainsi que les resultats lies a la sante sexuelle, afin d'ameliorer son intelligibilite et son applicabilite transculturelle. Nous souhaitions analyser la volonte des participants et leur capacite a repondre aux differentes thematiques abordees dans le projet de questionnaire, puis determiner si certaines questions avaient ete interpretees comme prevu selon les environnements geographiques et culturels. Methodes Nous avons mene des entretiens cognitifs (n = 645) repartis en trois periodes iteratives de collecte de donnees dans 19 pays entre mars 2022 et mars 2023, avec des participants de sexes, genres, ages et origines differents. Les personnes chargees de l'entretien ont utilise un guide pratique semi-structure pour interroger les participants sur la maniere dont ils ont interprete les questions et entrepris d'y repondre. Des equipes locales impliquees dans cette etude ont rempli des cadres d'analyse de donnees, puis nous avons organise des reunions de reflexion conjointes entre les periodes de collecte de donnees afin de recenser les questions qui se sont soldees par un echec. Resultats De maniere generale, nous avons constate que les participants etaient disposes a repondre au questionnaire, y compris aux thematiques les plus sensibles sur leur historique et leurs pratiques sexuelles. Nous avons identifie, dans le questionnaire initial, des problemes qui (i) ont eu un impact sur la volonte (acceptabilite) et la capacite (connaissances insuffisantes) des participants a y repondre pleinement; et/ou (ii) ont empeche les participants d'interpreter les questions comme prevu, notamment en raison d'une mauvaise formulation (erreur dans la question source), d'une absence de transposition culturelle et, dans de tres rares cas, d'une erreur de traduction. Dans le cadre de nos revisions, nous avons modifie l'ordre et la formulation des questions, ajoute des notes explicatives et un guide de mise en reuvre, mais aussi supprime les questions difficiles a transposer dans d'autres contextes culturels. Conclusion Nous avons montre qu'un questionnaire explorant les pratiques et experiences sexuelles ainsi que les resultats lies a la sante pouvait etre comprehensible et acceptable pour l'ensemble de la population dans divers contextes a travers le monde. Nous avons egalement souligne l'importance d'etablir des processus rigoureux de traduction et devaluation cognitive pour ce type de questionnaire. [phrase omitted] Objetivo Ajustar un cuestionario estandar sobre las practicas, las experiencias y los resultados relacionados con la salud sexual para mejorar su aplicabilidad e interpretabilidad transcultural. El objetivo consistia en explorar la disposicion y la capacidad de los participantes para responder al borrador del cuestionario y determinar si las preguntas se interpretaban segun lo previsto en diferentes entornos geograficos y culturales. Metodos Se realizaron entrevistas cognitivas (n = 645) en tres rondas iterativas de recopilacion de datos en 19 paises durante marzo de 2022 y marzo de 2023, con participantes de diversos sexos, generos, edades y regiones geograficas. Los entrevistadores utilizaron una guia de campo semiestructurada para obtener relatos de los participantes sobre sus procesos de interpretacion y respuesta a las preguntas del cuestionario. Los equipos de estudio locales completaron los marcos de analisis de datos y se celebraron reuniones conjuntas de analisis entre las rondas de recopilacion de datos para identificar fallos en las preguntas. Resultados En general, se observo que los participantes estaban dispuestos a responder incluso a las preguntas mas delicadas del cuestionario sobre biografia y practicas en materia sexual. Se identificaron problemas con el cuestionario original que (i) afectaban a la disposicion (aceptabilidad) y la capacidad (barreras de conocimiento) de los participantes para responder plenamente; o (ii) evitaban que los participantes interpretaran las preguntas segun lo previsto, incluida una redaccion deficiente (error en la pregunta original), portabilidad cultural y, muy raramente, error de traduccion. Las revisiones incluyeron el ajuste del orden y la redaccion de las preguntas, la adicion de preambulos y orientaciones de implementacion, y la eliminacion de preguntas con una portabilidad cultural limitada. Conclusion Se ha demostrado que un cuestionario que explora las practicas, las experiencias y los resultados relacionados con la salud sexual puede ser comprensible y aceptable para la poblacion general en diversos contextos mundiales. Ademas, se ha destacado la importancia de contar con procesos rigurosos para la traduccion y las pruebas cognitivas de un cuestionario de este tipo.

Abstract Risk stratification models based on cytogenetics and disease burden help identify high-risk patients with newly diagnosed multiple myeloma (NDMM). However, some high-risk patients remain undetected. This study evaluated the prognostic utility of the proportion of clonal plasma cells in the S-phase of the cell cycle for NDMM. Patients with active multiple myeloma diagnosed between 01/01/2013 and 01/31/2023 who underwent S-phase assessment were included. The S-phase proportion was calculated by analyzing DNA content between G0/G1 and G2/M peaks. Among 823 patients, 16% (135) had S-phase ≥2% at diagnosis. Patients with S-phase ≥2% exhibited significantly worse median progression-free survival (PFS) of 1.4 years (95% CI: 1.2–1.9) compared to 2.9 years (95% CI: 2.6–3.3) for those with S-phase

Abstract Introduction This study aimed to evaluate the metabolic differences between MM cells derived from patients with elevated serum LDH levels and those without elevated serum LDH levels to identify biological differences that could be exploited for therapeutic purposes. Methods We performed transcriptome assessments of CD138 + MM cells derived from patients with elevated serum LDH levels compared to those without elevated serum LDH levels and validated the findings in a larger public dataset. Functional metabolic assessments of our findings were performed using a combination of stable isotope resolved metabolomics (SIRM), bioenergetic flux measurement assays, and live cell analysis in human myeloma cell lines and primary MM patient cells. Results We identified SLC16A1, responsible for the formation of MCT1, a well-defined bi-directional transporter of lactate in and out of a cell with a predilection to importing extracellular lactate, as differentially expressed between the two groups. This finding was functionally confirmed by higher membranous MCT1 protein expression and SIRM on MM cells derived from patients with elevated serum LDH levels compared to those without elevated serum LDH levels. Finally, disrupting lactate transport in and out of CD138 + MM cells was maximally achievable only with dual inhibition of MCT1 and its partner, MCT4, which was preferentially more cytotoxic in MM cells derived from patients with elevated serum levels of LDH. Conclusion MCT1 mRNA and protein expression distinguish MM cells derived from patients with elevated serum LDH levels from those without elevated serum LDH levels. However, only dual inhibition of MCT1 and MCT4 can disrupt lactate transport in multiple myeloma (MM) cells, with preferential cytotoxicity in MM cells from patients with high serum LDH levels.

Multiple-choice quizzes (MCQs) are a popular form of assessment. A rapid shift to online assessment during the COVID-19 pandemic in 2020, drove the uptake of MCQs, yet limited invigilation and wide access to material on the internet allow students to solve the questions via internet search. ChatGPT, an artificial intelligence (AI) agent trained on a large language model, exacerbates this challenge as it responds to information retrieval questions with speed and a good level of accuracy. In this opinion piece, I contend that while the place of MCQ in summative assessment may be uncertain, current shortcomings of ChatGPT offer opportunities for continued formative use. I outline how ChatGPT's limitations can inform effective question design. I provide tips for effective multiple-choice question design and outline implications for both academics and learning developers. This piece contributes to emerging debate on the impact of artificial intelligence on assessment in higher education. Its purpose is threefold: to (1) enhance academics' understanding of effective MCQ design, (2) promote shared understanding and inform dialogue between academics and learning developers about MCQ assessment, and (3) highlight the potential implications on learning support.

Technological advances in radiation oncology are oriented towards improving treatment precision and tumor control. Among these advances, magnetic-resonance-image-guided radiation therapy (MRgRT) stands out, with technological advances to deliver targeted treatments adapted to a tumors anatomy on the day while minimizing incidental exposure to organs at risk, offering an unprecedented therapeutic advantage compared to X-ray-based IGRT delivery systems. This new technology changes the traditional workflow in radiation oncology and requires an evolution in team coordination to administer more precise treatments. Once implemented, it paves the way for newer indication for radiation therapy to safely deliver higher doses than ever before, with better preservation of healthy tissues to optimize patient outcomes. In this narrative review, we assess the technical aspects of the novel linear accelerators that can deliver MRgRT and summarize the available published experience to date, focusing on oncological results and future challenges.

Here, we demonstrate local writing and erasing of selected light-emitting defects using fs laser pulses in combination with hydrogen-based defect activation and passivation which also lead to rediscovering a potential Spin-photon qubit.

It is widely accepted that the next lepton collider beyond a Higgs factory would require center-of-mass energy of the order of up to 15 TeV. Since, given reasonable space and cost restrictions, conventional accelerator technology reaches its limits near this energy, high-gradient advanced acceleration concepts are attractive. Advanced and novel accelerators (ANAs) are leading candidates due to their ability to produce acceleration gradients on the order of 1-100 GV/m, leading to compact acceleration facilities. However, intermediate energy facilities (IEF) are required to test the critical technology elements on the way towards multi-TeV-class collliders. Here a science case for a 20-100 GeV center-of-mass energy ANA-based lepton collider that can be a candidate for an intermediate energy facility is presented. The IEF can provide numerous opportunities for high energy physics studies including precision Quantum Chromodynamics and Beyond the Standard Model physics measurements, investigation of charged particle interactions with extreme electromagnetic fields, and exploring muon and proton beam acceleration. Possible applications of this collider include the studies of γγ and electron beam-fixed target/beamdump collider designs. Thus, the goal of the proposed IEF is to both carry out particle physics measurements in the 20-100 GeV ranges as well as to serve as an ANA demonstrator facility.

We report a cluster of clade I monkeypox virus infections linked to sexual contact in the Democratic Republic of the Congo. Case investigations resulted in 5 reverse transcription PCR-confirmed infections; genome sequencing suggest they belonged to the same transmission chain. This finding demonstrates that mpox transmission through sexual contact extends beyond clade IIb.

Adrian Alfonso Almodovar Diaz,* Samhar Samer Alouch,* Yogesh Chawla, Wilson I Gonsalves Division of Hematology, Mayo Clinic, Rochester, MN, USA*These authors contributed equally to this workCorrespondence: Wilson I Gonsalves, Division of Hematology, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA, Tel +1 507-284-0969, Fax +1 507-266-4972, Email gonsalves.wilson@mayo.eduAbstract: Despite recent advancements in treatments, including proteasome inhibitors, immunomodulators, and anti-CD38 monoclonal antibodies, multiple myeloma (MM) remains mostly incurable with patients frequently experiencing disease relapses due to therapy resistance. Hence there is an urgent need for innovative treatments for patients with relapsed and/or refractory MM (RRMM). This review examines Belantamab mafodotin, the first antibody-drug conjugate (ADC) targeting B-cell maturation antigen (BCMA), which has shown efficacy in pre-clinical and clinical settings for RRMM. BCMA, a type III transmembrane glycoprotein critical for B cell functions, is predominantly expressed in malignant plasma cells making it a promising therapeutic target. ADCs, comprising a monoclonal antibody, a cytotoxic payload, and a linker, offer a targeted and potent therapeutic approach to cancer treatment. Belantamab mafodotin integrates an afucosylated monoclonal antibody and monomethyl auristatin F (MMAF) as its cytotoxic agent. It induces apoptosis in MM cells by disrupting microtubule formation and interfering with important signaling pathways. The series of DREAMM (Driving Excellence in Approaches to MM) studies have extensively evaluated Belantamab mafodotin in various clinical settings. This review provides a comprehensive overview of pre-clinical and clinical data supporting Belantamab mafodotin as a future therapeutic option for RRMM.Keywords: belantamab mafodotin, multiple myeloma, antibody-drug conjugate

Eucalyptus stands out as one of the most productive tree species for large-scale cultivation. However, like all cultivated crops, it requires specialized management practices, including the control of weeds, pathogens, and pests. Glyphosate is the most widely applied herbicide used in the essential weeding effort, and it ensures the sustainable management of eucalyptus cultivation in Brazil. Given the sensitivity of eucalyptus to glyphosate, existing weed control methods in young eucalyptus farms predominantly rely on protected mechanical or/and knapsack spraying. Both methods contribute to herbicide drift, which compromises tree yield and increases chemical waste due to uneven spraying. This study provides a detailed observation of the physiological parameters and long-term field performance of glyphosate-tolerant (HT), genetically modified (GM) eucalyptus developed by FuturaGene/Suzano S.A. and approved in Brazil for operational deployment. The HT GM eucalyptus events were meticulously evaluated to ensure high levels of glyphosate tolerance. This involved the direct application of herbicide on seedlings in greenhouse studies and on young trees in field conditions. The herbicide-treated GM eucalyptus in all trials demonstrated consistent growth and maintained physiological parameters comparable to their respective non-sprayed wild-type (WT) counterparts. The HT GM eucalyptus represents a significant advancement by enabling the direct application of glyphosate over the top of the trees to control the weeds within the planting row. This innovative approach minimizes the need for frequent mechanical and manual interventions, thereby lowering worker herbicide exposure, reducing the environmental impact of mechanical operations, and enhancing the overall efficiency and sustainability of HT GM eucalyptus stands.

Introducción: La sarcopenia se define como la pérdida de fuerza muscular asociada a disminución de la masa y/o de la funcionalidad muscular que puede provocar en el adulto mayor el síndrome de fragilidad, dependencia y óbito. Objetivo: determinar la frecuencia de la sarcopenia en los adultos mayores de 75 años, de la Unidad de Salud de la Familia del Barrio Santa Ana. Materiales y métodos: Estudio observacional, descriptivo, de corte transversal con muestreo no probabilístico por conveniência. Se incluyeron pacientes de ambos sexos a partir de 75 años de edad en los cuales se aplicó el cuestionario SARC-F y se tomó medidas antropométricas y de la fuerza de prensión manual. Para el análisis estadístico se utilizó el software Epi Info 7.2 6.0. Resultados: participaron 62 adultos, el 64,52% (n=40) fue del sexo femenino. El rango de edad fue de 75 a 92 años. Según el diagnóstico nutricional el 35,48% (n=22) presentó sobrepeso. El 4,84% (n=3) de la población fue diagnosticada con sarcopenia y el 50% (n=31) presentó probable sarcopenia. Conclusión: la frecuencia de sarcopenia encontrada en esta población fue menor que la global, por otro lado, las cifras de probable sarcopenia se asemejan a las encontrados en Latinoamérica.

Abstract Background To assess proportions of metastatic recurrence in women initially diagnosed with non-metastatic breast cancer by stage at diagnosis, breast cancer subtype, calendar period and age. Methods A systematic search of MEDLINE and Web of Science databases (January 2010–12 May 2022) was conducted. Studies reporting the proportion of distant metastatic recurrence in women with non-metastatic breast cancer were identified and outcomes and characteristics were extracted. Risk of bias was assessed independently by two reviewers. Random-effects meta-analyses of proportions were used to calculate pooled estimates and 95% confidence intervals (CIs). Results 193 studies covering over 280,000 patients were included in the main analysis. Pooled proportions of metastatic recurrence increased with longer median follow-up time from 12.2% (95% CI 10.5–14.0%) at 1–4 years post diagnosis, 14.3% (95% CI 12.9–15.7%) at 5–9 years to 23.3% (95% CI 20.1–26.8) at 10 years or more. Regional variation was observed with pooled estimates ranging from 11.0% (95% CI 8.5–13.7%) in Europe to 26.4% (95% CI 16.7–37.4%) in Africa (1–4 years follow-up). Proportions of recurrence were higher in studies with diagnosis before 2000 (22.2%, 95% CI 15.1–30.3) compared to studies with diagnosis from 2000 onwards (12.8%, 95% CI 11.7–14.0). At 1–4 years median follow-up, pooled proportions of metastatic recurrence were higher in women with hormone receptor negative (15.2%, 95% CI 12.0–18.7%) compared with receptor positive disease (9.6%, 95% CI 6.2–13.6%) and in women with locally advanced (33.2%, 95% CI 24.7–42.3%) relative to early disease at initial diagnosis (4.8%, 95% CI 2.5–7.8%). Proportions were higher in those under 50 years compared with 70+ years, 18.6% (95% CI 15.9–21.4%) versus 13.3% (95% CI 9.2, 18.0%), respectively. Heterogeneity was high in all meta-analyses and results should be interpreted with caution. Conclusions Higher proportions of metastatic recurrence in patients initially diagnosed at an advanced stage and in earlier calendar period emphasises the importance of early detection and treatment advancements. As the global number of breast cancer survivors increases, research and health policy efforts should be directed towards timely diagnosis and access to effective treatments and care. Study registration: PROSPERO CRD42022314500.

In 2017, the Department of Biology at Virginia Wesleyan University modified its two-course introductory sequence in response to high DFW rates (>50% scoring a D, F, or withdrawing) in the first semester. The revised curriculum created a new third course and moved content that many students struggled with from the first semester to the third semester (fall of year two). The new curriculum sequenced and scaffolded learning so that students faced more difficult material after a year of adjustment to the expectations of college-level biology courses. DFW rates in the revised first course showed a significant decrease from 51.2% to 30.4% during the four years post-implementation, with similar DFW rates in other courses pre- vs. post-revision. DFW rates in the new third course were still high (41.9%), but students seemed somewhat better prepared for the material in their second year. Pell status and Race/Ethnicity significantly impacted the DFW percentage, but nearly all groups showed a proportional improvement post-change. DFW rates did not vary significantly based on gender assigned at birth or first generation status. Fall to spring retention rates did not differ pre- vs. post-revision, suggesting other factors may be more important. Scores on the Major Field Assessment Test (MFAT) did not differ significantly between students that took the original two-course introductory sequence, the new three-course sequence, and those that transferred in. These results suggest that targeted interventions aimed at bottleneck courses can improve student course success without negatively affecting long-term learning outcomes. Departments should scaffold program content in a logical approach that supports the transition of students from high school to more challenging, college level expectations.

Despite their widespread adoption and recognised benefits, rubrics have been critiqued for their potential misalignment with student needs. The voices of international students, who constitute a substantial portion of the higher education population, remain underrepresented. This study examines the perspectives of international undergraduate students on assessment rubrics in a UK business school. Employing a participatory research approach and focus groups, the findings reveal challenges students face related to rubric design, rubric use during and post-assessment, and prior experience with rubrics. This study concludes that enhancing the accessibility of rubrics for international students--"via" thoughtful design, timely introduction, focused discussions, pertinent activities and seamless integration throughout the assessment cycle--is paramount. The article advocate for more inclusive and effective rubric practices tailored to the diverse needs of the international student body.

Background and Context: Differences in children's and adolescents' initial attitudes about computing and other STEM fields may form during middle school and shape decisions leading to career entry. Early emerging differences in career interest may propagate a lack of diversity in computer science and programming fields. Objective: Though middle school is recognized as a formative period in the development of career interest, there appears to be a gap in research considering growth disparities in students' attitudes towards computer programming. We examine outcomes related to students' use of an e-learning platform designed to promote exposure to computer science content. We consider growth in middle school students' attitudes towards computer programming during an academic year while controlling for variation in key baseline factors. Method: We tracked growth in attitudes towards computer programming among middle school students (N = 610; M[subscript age] = 12.07) in schools serving underrepresented minority (URM) students (74.7% URM) during an academic year in which they used an online platform curating computer programming educational content. Findings: We found baseline differences in students' interest and aspirations toward computer programming on the basis of gender and underrepresented status, after controlling for math attitudes. There was evidence of initial growth in all four domains of computer programming attitudes, irrespective of gender or underrepresented status. Implications: These findings provide a framework for studying changes in students' computer programming attitudes, which may help in addressing workforce participation disparities. Future work is needed to promote early computer programming attitudes among all students. [This article was written with Curated Pathways to Innovation.]

Defect engineering is foundational to classical electronic device development and for emerging quantum devices. Here, we report on defect engineering of silicon with ion pulses from a laser accelerator in the laser intensity range of 1019 W cm−2 and ion flux levels of up to 1022 ions cm−2 s−1, about five orders of magnitude higher than conventional ion implanters. Low energy ions from plasma expansion of the laser-foil target are implanted near the surface and then diffuse into silicon samples locally pre-heated by high energy ions from the same laser-ion pulse. Silicon crystals exfoliate in the areas of highest energy deposition. Color centers, predominantly W and G-centers, form directly in response to ion pulses without a subsequent annealing step. We find that the linewidth of G-centers increases with high ion flux faster than the linewidth of W-centers, consistent with density functional theory calculations of their electronic structure. Intense ion pulses from a laser-accelerator drive materials far from equilibrium and enable direct local defect engineering and high flux doping of semiconductors.

Abstract. Objectives:. This study examined the benefits of a dedicated social worker in the fracture clinic setting as perceived by patients and caregivers. Methods:. This cross-sectional survey engaged patients aged 18 and older presenting to the fracture clinic associated with a level 1 trauma center. Surveys were available in English and Arabic and included 11 questions designed to measure level of agreement with various aspects of social worker presence in the outpatient fracture clinic. Results:. A total of 199 patients and caregivers participated in this study. Most of the participants were female (61.8%) and older than the age of 50 (57.1%). While there was nuance in the circumstances and issues participants felt were appropriate for social worker assistance, most (95.4%) found the general premise of having a dedicated social worker available in the fracture clinic to be acceptable and believed that it would be beneficial to fracture clinic patients. Participants indicated that social workers could support trauma patients with multiple issues (≥60% level of agreement across all items). Conclusions:. Orthopaedic trauma patients and their caregivers overwhelmingly support the addition of a dedicated social worker to the fracture clinic, with a high level of agreement across demographic groups and proposed social worker interventions. The patient and caregiver population finds the fracture clinic to be an appropriate and viable setting for the mitigation of nonphysical impacts of orthopaedic trauma. These findings can inform the development of potential future additions of social services to the fracture clinic. Level of Evidence:. Level IV.