26 results on '"A. N. Kitsiou"'
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2. Late metabolic trapping of
- Author
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Anastasia N, Kitsiou and Vasken, Dilsizian
- Subjects
Nitrogen Radioisotopes ,Ammonia ,Coronary Circulation ,Humans ,Tomography, X-Ray Computed - Published
- 2021
3. Position effect, cryptic complexity, and direct gene disruption as disease mechanisms in de novo apparently balanced translocation cases
- Author
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Aristidou, C. Theodosiou, A. Bak, M. Mehrjouy, M.M. Constantinou, E. Alexandrou, A. Papaevripidou, I. Christophidou-Anastasiadou, V. Skordis, N. Kitsiou-Tzeli, S. Tommerup, N. Sismani, C.
- Abstract
The majority of apparently balanced translocation (ABT) carriers are phenotypically normal. However, several mechanisms were proposed to underlie phenotypes in affected ABT cases. In the current study, whole-genome mate-pair sequencing (WG-MPS) followed by Sanger sequencing was applied to further characterize de novo ABTs in three affected individuals. WG-MPS precisely mapped all ABT breakpoints and revealed three possible underlying molecular mechanisms. Firstly, in a t(X;1) carrier with hearing loss, a highly skewed Xinactivation pattern was observed and the der(X) breakpoint mapped ∼87kb upstream an Xlinked deafness gene namely POU3F4, thus suggesting an underlying long-range position effect mechanism. Secondly, cryptic complexity and a chromothripsis rearrangement was identified in a t(6;7;8;12) carrier with intellectual disability. Two translocations and a heterozygous deletion disrupted SOX5; a dominant nervous system development gene previously reported in similar patients. Finally, a direct gene disruption mechanism was proposed in a t (4;9) carrier with dysmorphic facial features and speech delay. In this case, the der(9) breakpoint directly disrupted NFIB, a gene involved in lung maturation and development of the pons with important functions in main speech processes. To conclude, in contrast to familial ABT cases with identical rearrangements and discordant phenotypes, where translocations are considered coincidental, translocations seem to be associated with phenotype presentation in affected de novo ABT cases. In addition, this study highlights the importance of investigating both coding and non-coding regions to decipher the underlying pathogenic mechanisms in these patients, and supports the potential introduction of low coverage WGMPS in the clinical investigation of de novo ABTs. © 2018 Aristidou et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Published
- 2018
4. Abstracts
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V. Dunet, A. Dabiri, G. Allenbach, A. Goyeneche Achigar, B. Waeber, F. Feihl, R. Heinzer, J. O. Prior, J. E. Van Velzen, J. D. Schuijf, F. R. De Graaf, M. A. De Graaf, M. J. Schalij, L. J. Kroft, A. De Roos, J. W. Jukema, E. E. Van Der Wall, J. J. Bax, E. Lankinen, A. Saraste, T. Noponen, R. Klen, M. Teras, T. Kokki, S. Kajander, M. Pietila, H. Ukkonen, J. Knuuti, A. P. Pazhenkottil, R. N. Nkoulou, J. R. Ghadri, B. A. Herzog, R. R. Buechel, S. M. Kuest, M. Wolfrum, O. Gaemperli, L. Husmann, P. A. Kaufmann, D. Andreini, G. Pontone, S. Mushtaq, L. Antonioli, E. Bertella, A. Formenti, S. Cortinovis, G. Ballerini, C. Fiorentini, M. Pepi, A. S. Koh, J. S. Flores, F. Y. J. Keng, R. S. Tan, T. S. J. Chua, A. D. Annoni, G. Tamborini, M. Fusari, A. L. Bartorelli, S. H. Ewe, A. C. T. Ng, V. Delgado, J. Schuijf, F. Van Der Kley, A. Colli, A. De Weger, N. A. Marsan, K. H. Yiu, A. C. Ng, S. A. J. Timmer, P. Knaapen, T. Germans, P. A. Dijkmans, M. Lubberink, J. M. Ten Berg, F. J. Ten Cate, I. K. Russel, A. A. Lammertsma, A. C. Van Rossum, Y. Y. Wong, G. Ruiter, P. Raijmakers, W. J. Van Der Laarse, N. Westerhof, A. Vonk-Noordegraaf, G. Youssef, E. Leung, G. Wisenberg, C. Marriot, K. Williams, J. Etele, R. A. Dekemp, J. Dasilva, D. Birnie, R. S. B. Beanlands, R. C. Thompson, A. H. Allam, L. S. Wann, A. H. Nureldin, G. Adelmaksoub, I. Badr, M. L. Sutherland, J. D. Sutherland, M. I. Miyamoto, G. S. Thomas, H. J. Harms, S. De Haan, M. C. Huisman, R. C. Schuit, A. D. Windhorst, C. Allaart, A. J. Einstein, T. Khawaja, C. Greer, A. Chokshi, M. Jones, K. Schaefle, K. Bhatia, D. Shimbo, P. C. Schulze, A. Srivastava, R. Chettiar, J. Moody, C. Weyman, D. Natale, W. Bruni, Y. Liu, E. Ficaro, A. J. Sinusas, A. Peix, E. Batista, L. O. Cabrera, K. Padron, L. Rodriguez, B. Sainz, V. Mendoza, R. Carrillo, Y. Fernandez, E. Mena, A. Naum, T. Bach-Gansmo, N. Kleven-Madsen, M. Biermann, B. Johnsen, J. Aase Husby, S. Rotevatn, J. E. Nordrehaug, J. Schaap, R. M. Kauling, M. C. Post, B. J. W. M. Rensing, J. F. Verzijlbergen, J. Sanchez, G. Giamouzis, N. Tziolas, P. Georgoulias, G. Karayannis, A. Chamaidi, N. Zavos, K. Koutrakis, G. Sitafidis, J. Skoularigis, F. Triposkiadis, S. Radovanovic, A. Djokovic, D. V. Simic, M. Krotin, A. Savic-Radojevic, M. Pljesa-Ercegovac, M. Zdravkovic, J. Saponjski, S. Jelic, T. Simic, R. Eckardt, B. J. Kjeldsen, L. I. Andersen, T. Haghfelt, P. Grupe, A. Johansen, B. Hesse, H. Pena, G. Cantinho, M. Wilk, Y. Srour, F. Godinho, N. Zafrir, A. Gutstein, I. Mats, A. Battler, A. Solodky, E. Sari, N. Singh, A. Vara, A. M. Peters, A. De Belder, S. Nair, N. Ryan, R. James, S. Dizdarevic, G. Depuey, M. Friedman, R. Wray, R. Old, H. Babla, B. Chuanyong, J. Maddahi, E. Tragardh Johansson, K. Sjostrand, L. Edenbrandt, S. Aguade-Bruix, G. Cuberas-Borros, M. N. Pizzi, M. Sabate-Fernandez, G. De Leon, D. Garcia-Dorado, J. Castell-Conesa, J. Candell-Riera, D. Casset-Senon, M. Edjlali-Goujon, D. Alison, A. Delhommais, P. Cosnay, C. S. Low, A. Notghi, J. O'brien, A. C. Tweddel, N. Bingham, P. O Neil, M. Harbinson, O. Lindner, W. Burchert, M. Schaefers, C. Marcassa, R. Campini, P. Calza, O. Zoccarato, A. Kisko, J. Kmec, M. Babcak, M. Vereb, M. Vytykacova, J. Cencarik, P. Gazdic, J. Stasko, A. Abreu, E. Pereira, L. Oliveira, P. Colarinha, V. Veloso, I. Enriksson, G. Proenca, P. Delgado, L. Rosario, J. Sequeira, I. Kosa, I. Vassanyi, C. S. Egyed, G. Y. Kozmann, S. Morita, M. Nanasato, I. Nanbu, Y. Yoshida, H. Hirayama, A. Allam, A. Sharef, I. Shawky, M. Farid, M. Mouden, J. P. Ottervanger, J. R. Timmer, M. J. De Boer, S. Reiffers, P. L. Jager, S. Knollema, G. M. Nasr, M. Mohy Eldin, M. Ragheb, I. Casans-Tormo, R. Diaz-Exposito, F. J. Hurtado-Mauricio, R. Ruano, M. Diego, F. Gomez-Caminero, C. Albarran, A. Martin De Arriba, A. Rosero, R. Lopez, C. Martin Luengo, J. R. Garcia-Talavera, I. E. K. Laitinen, M. Rudelius, E. Weidl, G. Henriksen, H. J. Wester, M. Schwaiger, X. B. Pan, T. Schindler, A. Quercioli, H. Zaidi, O. Ratib, J. M. Declerck, E. Alexanderson Rosas, R. Jacome, M. Jimenez-Santos, E. Romero, M. A. Pena-Cabral, A. Meave, J. Gonzalez, F. Rouzet, L. Bachelet, J. M. Alsac, M. Suzuki, L. Louedec, A. Petiet, F. Chaubet, D. Letourneur, J. B. Michel, D. Le Guludec, A. Aktas, A. Cinar, G. Yaman, T. Bahceci, K. Kavak, A. Gencoglu, A. Jimenez-Heffernan, E. Sanchez De Mora, J. Lopez-Martin, R. Lopez-Aguilar, C. Ramos, C. Salgado, A. Ortega, C. Sanchez-Gonzalez, J. Roa, A. Tobaruela, S. V. Nesterov, O. Turta, M. Maki, C. Han, D. Daou, M. Tawileh, S. O. Chamouine, C. Coaguila, E. Mariscal-Labrador, N. Kisiel-Gonzalez, P. De Araujo Goncalves, P. J. Sousa, H. Marques, J. O'neill, J. Pisco, R. Cale, J. Brito, A. Gaspar, F. P. Machado, J. Roquette, M. Martinez, G. Melendez, E. Kimura, J. M. Ochoa, A. M. Alessio, A. Patel, R. Lautamaki, F. M. Bengel, J. B. Bassingthwaighte, J. H. Caldwell, K. Rahbar, H. Seifarth, M. Schafers, L. Stegger, T. Spieker, A. Hoffmeier, D. Maintz, H. Scheld, O. Schober, M. Weckesser, H. Aoki, I. Matsunari, K. Kajinami, M. Martin Fernandez, M. Barreiro Perez, O. V. Fernandez Cimadevilla, D. Leon Duran, E. Velasco Alonso, J. P. Florez Munoz, L. H. Luyando, C. Templin, C. E. Veltman, J. H. C. Reiber, S. Venuraju, A. Yerramasu, S. Atwal, A. Lahiri, T. Kunimasa, M. Shiba, K. Ishii, J. Aikawa, E. S. J. Kroner, K. T. Ho, Q. W. Yong, K. C. Chua, C. Panknin, C. J. Roos, J. M. Van Werkhoven, A. J. Witkowska-Grzeslo, M. J. Boogers, D. V. Anand, D. Dey, D. Berman, F. Mut, R. Giubbini, L. Lusa, T. Massardo, A. Iskandrian, M. Dondi, A. Sato, Y. Kakefuda, E. Ojima, T. Adachi, A. Atsumi, T. Ishizu, Y. Seo, M. Hiroe, K. Aonuma, M. Kruk, R. Pracon, C. Kepka, J. Pregowski, A. Kowalewska, M. Pilka, M. Opolski, I. Michalowska, Z. Dzielinska, M. Demkow, V. Stoll, N. Sabharwal, A. Chakera, O. Ormerod, H. Fernandes, M. Bernardes, E. Martins, P. Oliveira, T. Vieira, G. Terroso, A. Oliveira, T. Faria, F. Ventura, J. Pereira, S. Fukuzawa, M. Inagaki, J. Sugioka, A. Ikeda, S. Okino, J. Maekawa, T. Uchiyama, N. Kamioka, S. Ichikawa, M. Afshar, R. Alvi, N. Aguilar, R. Ippili, H. Shaqra, J. Bella, N. Bhalodkar, A. Dos Santos, M. Daicz, L. O. Cendoya, H. G. Marrero, J. Casuscelli, M. Embon, G. Vera Janavel, E. Duronto, E. P. Gurfinkel, C. M. Cortes, Y. Takeishi, K. Nakajima, Y. Yamasaki, T. Nishimura, K. Hayes Brown, F. Collado, M. Alhaji, J. Green, S. Alexander, R. Vashistha, S. Jain, F. Aldaas, J. Shanes, R. Doukky, K. Ashikaga, Y. J. Akashi, M. Uemarsu, R. Kamijima, K. Yoneyama, K. Omiya, Y. Miyake, Y. Brodov, U. Raval, A. Berezin, V. Seden, E. Koretskaya, T. A. Panasenko, S. Matsuo, S. Kinuya, J. Chen, R. J. Van Bommel, B. Van Der Hiel, P. Dibbets-Schneider, E. V. Garcia, I. Rutten-Vermeltfoort, M. M. J. Gevers, B. Verhoeven, A. B. Dijk Van, E. Raaijmakers, P. G. H. M. Raijmakers, J. E. Engvall, M. Gjerde, J. De Geer, E. Olsson, P. Quick, A. Persson, M. Mazzanti, M. Marini, L. Pimpini, G. P. Perna, C. Marciano, P. Gargiulo, M. Galderisi, C. D'amore, G. Savarese, L. Casaretti, S. Paolillo, A. Cuocolo, P. Perrone Filardi, M. Al-Amoodi, E. C. Thompson, K. Kennedy, K. A. Bybee, A. I. Mcghie, J. H. O'keefe, T. M. Bateman, R. L. F. Van Der Palen, A. M. Mavinkurve-Groothuis, B. Bulten, L. Bellersen, H. W. M. Van Laarhoven, L. Kapusta, L. F. De Geus-Oei, P. P. Pollice, M. B. Bonifazi, F. P. Pollice, I. P. Clements, D. O. Hodge, C. G. Scott, M. De Ville De Goyet, B. Brichard, T. Pirotte, S. Moniotte, R. A. Tio, A. Elvan, R. A. I. O. Dierckx, R. H. J. A. Slart, T. Furuhashi, M. Moroi, H. Hase, N. Joki, H. Masai, R. Nakazato, H. Fukuda, K. Sugi, K. Kryczka, E. Kaczmarska, J. Petryka, L. Mazurkiewicz, W. Ruzyllo, P. Smanio, E. Vieira Segundo, M. Siqueira, J. Kelendjian, J. Ribeiro, J. Alaca, M. Oliveira, F. Alves, I. Peovska, J. Maksimovic, M. Vavlukis, N. Kostova, D. Pop Gorceva, V. Majstorov, M. Zdraveska, S. Hussain, M. Djearaman, E. Hoey, L. Morus, O. Erinfolami, A. Macnamara, M. P. Opolski, A. Witkowski, V. Berti, F. Ricci, R. Gallicchio, W. Acampa, G. Cerisano, C. Vigorito, R. Sciagra', A. Pupi, H. Sliem, F. M. Collado, S. Schmidt, A. Maheshwari, R. Kiriakos, V. Mwansa, S. Ljubojevic, S. Sedej, M. Holzer, G. Marsche, V. Marijanski, J. Kockskaemper, B. Pieske, A. Ricalde, G. Alexanderson, A. Mohani, P. Khanna, A. Sinusas, F. Lee, V. A. Pinas, B. L. F. Van Eck-Smit, H. J. Verberne, C. M. De Bruin, G. Guilhermina, L. Jimenez-Angeles, O. Ruiz De Jesus, O. Yanez-Suarez, E. Vallejo, E. Reyes, M. Chan, M. L. Hossen, S. R. Underwood, A. Karu, S. Bokhari, V. Pineda, L. M. Gracia-Sanchez, A. Garcia-Burillo, K. Zavadovskiy, Y. U. Lishmanov, W. Saushkin, I. Kovalev, A. Chernishov, A. Annoni, M. Tarkia, T. Saanijoki, V. Oikonen, T. Savunen, M. A. Green, M. Strandberg, A. Roivainen, M. C. Gaeta, C. Artigas, J. Deportos, L. Geraldo, A. Flotats, V. La Delfa, I. Carrio, W. J. Laarse, M. M. Izquierdo Gomez, J. Lacalzada Almeida, A. Barragan Acea, A. De La Rosa Hernandez, R. Juarez Prera, G. Blanco Palacios, J. A. Bonilla Arjona, J. J. Jimenez Rivera, J. L. Iribarren Sarrias, I. Laynez Cerdena, A. Dedic, A. Rossi, G. J. R. Ten Kate, A. Dharampal, A. Moelker, T. W. Galema, N. Mollet, P. J. De Feyter, K. Nieman, D. Trabattoni, A. Broersen, M. Frenay, M. M. Boogers, P. H. Kitslaar, J. Dijkstra, D. A. Annoni, M. Muratori, N. Johki, M. Tokue, A. S. Dharampal, A. C. Weustink, L. A. E. Neefjes, S. L. Papadopoulou, C. Chen, N. R. A. Mollet, E. H. Boersma, G. P. Krestin, J. A. Purvis, D. Sharma, S. M. Hughes, D. S. Berman, R. Taillefer, J. Udelson, M. Devine, J. Lazewatsky, G. Bhat, D. Washburn, D. Patel, T. Mazurek, S. Tandon, S. Bansal, S. Inzucchi, L. Staib, J. Davey, D. Chyun, L. Young, F. Wackers, M. T. Harbinson, G. Wells, J. Dougan, S. Borges-Neto, H. Phillips, A. Farzaneh-Far, Z. Starr, L. K. Shaw, M. Fiuzat, C. O'connor, M. Henzlova, W. L. Duvall, A. Levine, U. Baber, L. Croft, S. Sahni, S. Sethi, L. Hermann, A. Nureldin, A. Gomaa, M. A. T. Soliman, H. A. R. Hany, F. De Graaf, A. Pazhenkottil, H. M. J. Siebelink, J. H. Reiber, M. Ayub, T. Naveed, M. Azhar, A. Van Tosh, T. L. Faber, J. R. Votaw, N. Reichek, B. Pulipati, C. Palestro, K. J. Nichols, K. Okuda, Y. Kirihara, T. Ishikawa, J. Taki, M. Yoshita, M. Yamada, A. Salacata, S. Keavey, V. Chavarri, J. Mills, H. Nagaraj, P. Bhambhani, D. E. Kliner, P. Soman, J. Heo, A. E. Iskandrian, M. Jain, B. Lin, A. Walker, C. Nkonde, S. Bond, A. Baskin, J. Declerck, M. E. Soto, G. Mendoza, M. Aguilar, S. P. Williams, G. Colice, J. R. Mcardle, A. Lankford, D. K. Kajdasz, C. R. Reed, L. Angelini, F. Angelozzi, G. Ascoli, A. Jacobson, H. J. Lessig, M. C. Gerson, M. D. Cerqueira, J. Narula, M. Uematsu, K. Kida, K. Suzuki, P. E. Bravo, K. Fukushima, M. Chaudhry, J. Merrill, A. Alonso Tello, J. F. Rodriguez Palomares, G. Marti Aguasca, S. Aguade Bruix, V. Aliaga, P. Mahia, T. Gonzalez-Alujas, J. Candell, A. Evangelista, R. Mlynarski, A. Mlynarska, M. Sosnowski, B. Zerahn, P. Hasbak, C. E. Mortensen, H. F. Mathiesen, M. Andersson, D. Nielsen, L. Ferreira Santos, M. J. Ferreira, D. Ramos, D. Moreira, M. J. Cunha, A. Albuquerque, A. Moreira, J. Oliveira Santos, G. Costa, L. A. Providencia, Y. Arita, S. Kihara, N. Mitsusada, M. Miyawaki, H. Ueda, H. Hiraoka, Y. Matsuzawa, J. Askew, M. O'connor, L. Jordan, R. Ruter, R. Gibbons, T. Miller, L. Emmett, A. Ng, N. Sorensen, R. Mansberg, L. Kritharides, T. Gonzalez, H. Majmundar, N. P. Coats, S. Vernotico, J. H. Doan, T. M. Hernandez, M. Evini, A. D. Hepner, T. K. Ip, W. A. Chalela, A. M. Falcao, L. O. Azouri, J. A. F. Ramires, J. C. Meneghetti, F. Manganelli, M. Spadafora, P. Varrella, G. Peluso, R. Sauro, E. Di Lorenzo, F. Rotondi, S. Daniele, P. Miletto, A. J. M. Rijnders, B. W. Hendrickx, W. Van Der Bruggen, Y. G. C. J. America, P. J. Thorley, F. U. Chowdhury, C. J. Dickinson, S. I. Sazonova, I. Y. U. Proskokova, A. M. Gusakova, S. M. Minin, Y. U. B. Lishmanov, V. V. Saushkin, G. Rodriguez, F. Roffe, H. Ilarraza, D. Bialostozky, A. N. Kitsiou, P. Arsenos, I. Tsiantis, S. Charizopoulos, S. Karas, R. C. Vidal Perez, M. Garrido, V. Pubul, S. Argibay, C. Pena, M. Pombo, A. B. Ciobotaru, A. Sanchez-Salmon, A. Ruibal Morell, J. R. Gonzalez-Juanatey, E. Rodriguez-Gomez, B. Martinez, D. Pontillo, F. Benvissuto, F. Fiore Melacrinis, S. Maccafeo, E. V. Scabbia, R. Schiavo, Y. Golzar, C. Gidea, J. Golzar, D. Pop-Gorceva, M. Zdravkovska, S. Stojanovski, L. J. Georgievska-Ismail, T. Katsikis, A. Theodorakos, A. Kouzoumi, M. Koutelou, Y. Yoshimura, T. Toyama, H. Hoshizaki, S. Ohshima, M. Inoue, T. Suzuki, A. Uitterdijk, M. Dijkshoorn, M. Van Straten, W. J. Van Der Giessen, D. J. Duncker, D. Merkus, G. Platsch, J. Sunderland, C. Tonge, P. Arumugam, T. Dey, H. Wieczorek, R. Bippus, R. L. Romijn, B. E. Backus, T. Aach, M. Lomsky, L. Johansson, J. Marving, S. Svensson, J. L. Pou, F. P. Esteves, P. Raggi, R. Folks, Z. Keidar, J. W. Askew, L. Verdes, L. Campos, V. Gulyaev, A. Pankova, J. Santos, S. Carmona, I. Henriksson, A. Prata, M. Carrageta, A. I. Santos, K. Yoshinaga, M. Naya, C. Katoh, O. Manabe, S. Yamada, H. Iwano, S. Chiba, H. Tsutsui, N. Tamaki, I. Vassiliadis, E. Despotopoulos, O. Kaitozis, E. Hatzistamatiou, R. Thompson, J. Hatch, M. Zink, B. S. Gu, G. D. Bae, C. M. Dae, G. H. Min, E. J. Chun, S. I. Choi, M. Al-Mallah, K. Kassem, O. Khawaja, D. Goodman, D. Lipkin, L. Christiaens, B. Bonnet, J. Mergy, D. Coisne, J. Allal, N. Dias Ferreira, D. Leite, J. Rocha, M. Carvalho, D. Caeiro, N. Bettencourt, P. Braga, V. Gama Ribeiro, U. S. Kristoffersen, A. M. Lebech, H. Gutte, R. S. Ripa, N. Wiinberg, C. L. Petersen, G. Jensen, A. Kjaer, C. Bai, R. Conwell, R. D. Folks, L. Verdes-Moreiras, D. Manatunga, A. F. Jacobson, D. Belzer, Y. Hasid, M. Rehling, R. H. Poulsen, L. Falborg, J. T. Rasmussen, L. N. Waehrens, C. W. Heegaard, J. M. U. Silvola, S. Forsback, J. O. Laine, S. Heinonen, S. Ylaherttuala, A. Broisat, M. Ruiz, N. C. Goodman, J. Dimastromatteo, D. K. Glover, F. Hyafil, F. Blackwell, G. Pavon-Djavid, L. Sarda-Mantel, L. J. Feldman, A. Meddahi-Pelle, V. Tsatkin, Y.- H. Liu, R. De Kemp, P. J. Slomka, R. Klein, G. Germano, R. S. Beanlands, A. Rohani, V. Akbari, J. G. J. Groothuis, M. Fransen, A. M. Beek, S. L. Brinckman, M. R. Meijerink, M. B. M. Hofman, C. Van Kuijk, S. Kogure, E. Yamashita, J. Murakami, R. Kawaguchi, H. Adachi, S. Oshima, S. Minin, S. Popov, Y. U. Saushkina, G. Savenkova, D. Lebedev, E. Alexandridis, D. Rovithis, C. Parisis, I. Sazonova, V. Saushkin, V. Chernov, L. Zaabar, H. Bahri, S. Hadj Ali, A. Sellem, I. Slim, N. El Kadri, H. Slimen, H. Hammami, S. Lucic, A. Peter, S. Tadic, K. Nikoletic, R. Jung, M. Lucic, K. Tagil, D. Jakobsson, S.- E. Svensson, P. Wollmer, L. Leccisotti, L. Indovina, L. Paraggio, M. L. Calcagni, A. Giordano, M. Kapitan, A. Paolino, M. Nunez, J. Sweeny, N. Kulkarni, K. Guma, Y. Akashi, M. Takano, M. Takai, S. Koh, F. Miyake, N. Torun, G. Durmus Altun, A. Altun, E. Kaya, H. Saglam, D. T. Matsuoka, A. Sanchez, C. Bartolozzi, D. Padua, G. Ponta, A. Ponte, A. Carneiro, A. Thom, R. Ashrafi, P. Garg, G. Davis, A. Falcao, M. Costa, F. Bussolini, J. A. C. Meneghetti, M. Tobisaka, E. Correia, J. W. Jansen, P. A. Van Der Vleuten, T. P. Willems, F. Zijlstra, M. Sato, K. Taniguchi, M. Kurabayashi, D. Pop Gjorcheva, M. Zdraveska-Kochovska, K. Moriwaki, A. Kawamura, K. Watanabe, T. Omura, S. Sakabe, T. Seko, A. Kasai, M. Ito, M. Obana, T. Akasaka, C. Hruska, D. Truong, C. Pletta, D. Collins, C. Tortorelli, D. Rhodes, M. El-Prince, A. Martinez-Moeller, M. Marinelli, S. Weismueller, C. Hillerer, B. Jensen, S. G. Nekolla, H. Wakabayashi, K. Tsukamoto, S. M. E. A. Baker, K. M. H. S. Sirajul Haque, A. Siddique, S. Krishna Banarjee, A. Ahsan, F. Rahman, M. Mukhlesur Rahman, T. Parveen, M. Lutfinnessa, F. Nasreen, H. Sano, S. Naito, M. L. De Rimini, G. Borrelli, F. Baldascino, P. Calabro, C. Maiello, A. Russo, C. Amarelli, P. Muto, I. Danad, P. G. Raijmakers, Y. E. Appelman, O. S. Hoekstra, J. T. Marcus, A. Boonstra, D. V. Ryzhkova, T. V. Kuzmina, O. S. Borodina, M. A. Trukshina, I. S. Kostina, H. Hommel, G. Feuchtner, O. Pachinger, G. Friedrich, A. M. Stel, J. W. Deckers, V. Gama, A. Ciarka, L. A. Neefjes, N. R. Mollet, E. J. Sijbrands, J. Wilczek, C. Llibre Pallares, O. Abdul-Jawad Altisent, H. Cuellar Calabria, P. Mahia Casado, M. T. Gonzalez-Alujas, A. Evangelista Masip, D. Garcia-Dorado Garcia, Y. Tekabe, X. Shen, Q. Li, J. Luma, D. Weisenberger, A. M. Schmidt, R. Haubner, L. Johnson, L. Sleiman, S. Thorn, M. Hasu, M. Thabet, J. N. Dasilva, S. C. Whitman, D. Genovesi, A. Giorgetti, A. Gimelli, G. Cannizzaro, F. Bertagna, G. Fagioli, M. Rossi, R. Bonini, P. Marzullo, C. A. Paterson, S. A. Smith, A. D. Small, N. E. R. Goodfield, W. Martin, S. Nekolla, H. Sherif, S. Reder, M. Yu, A. Kusch, D. Li, J. Zou, M. S. Lloyd, K. Cao, D. W. Motherwell, A. Rice, G. M. Mccurrach, S. M. Cobbe, M. C. Petrie, I. Al Younis, E. Van Der Wall, T. Mirza, M. Raza, H. Hashemizadeh, L. Santos, B. A. Krishna, F. Perna, M. Lago, M. Leo, G. Pelargonio, G. Bencardino, M. L. Narducci, M. Casella, F. Bellocci, S. Kirac, O. Yaylali, M. Serteser, T. Yaylali, A. Okizaki, Y. Urano, M. Nakayama, S. Ishitoya, J. Sato, Y. Ishikawa, M. Sakaguchi, N. Nakagami, T. Aburano, S. V. Solav, R. Bhandari, S. Burrell, S. Dorbala, I. Bruno, C. Caldarella, A. Collarino, M. V. Mattoli, A. Stefanelli, A. Cannarile, F. Maggi, V. Soukhov, S. Bondarev, A. Yalfimov, M. Khan, P. P. Priyadharshan, G. Chandok, T. Aziz, M. Avison, R. A. Smith, D. S. Bulugahapitya, T. Vakhtangadze, F. Todua, M. Baramia, G. Antelava, N.- C. Roche, P. Paule, S. Kerebel, J.- M. Gil, L. Fourcade, A. Tzonevska, K. Tzvetkov, M. Atanasova, V. Parvanova, A. Chakarova, E. Piperkova, B. Kocabas, H. Muderrisoglu, C. P. Allaart, E. Entok, S. Simsek, B. Akcay, I. Ak, E. Vardareli, M. Stachura, P. J. Kwasiborski, G. J. Horszczaruk, E. Komar, A. Cwetsch, B. Zraik, R. Morales Demori, A. D. J. Almeida, M. E. Siqueira, E. Vieira, I. Balogh, G. Kerecsen, E. Marosi, Z. S. Szelid, A. Sattar, T. Swadia, J. Chattahi, W. Qureshi, F. Khalid, A. Gonzalez, S. Hechavarria, K. Takamura, S. Fujimoto, R. Nakanishi, S. Yamashina, A. Namiki, J. Yamazaki, K. Koshino, Y. Hashikawa, N. Teramoto, M. Hikake, S. Ishikane, T. Ikeda, H. Iida, Y. Takahashi, N. Oriuchi, H. Higashino, K. Endo, T. Mochizuki, K. Murase, A. Baali, R. Moreno, M. Chau, H. Rousseau, F. Nicoud, P. Dolliner, L. Brammen, G. Steurer, T. Traub-Weidinger, P. Ubl, P. Schaffarich, G. Dobrozemsky, A. Staudenherz, M. Ozgen Kiratli, B. Temelli, N. B. Kanat, T. Aksoy, G. A. Slavich, G. Piccoli, M. Puppato, S. Grillone, D. Gasparini, S. Perruchoud, C. Poitry-Yamate, M. Lepore, R. Gruetter, T. Pedrazzini, D. Anselm, A. Anselm, H. Atkins, J. Renaud, R. Dekemp, I. Burwash, A. Guo, R. Beanlands, C. Glover, I. Vilardi, B. Zangheri, L. Calabrese, P. Romano, A. Bruno, O. C. Fernandez Cimadevilla, V. A. Uusitalo, M. Luotolahti, M. Wendelin-Saarenhovi, J. Sundell, O. Raitakari, S. Huidu, R. Gadiraju, M. Ghesani, Q. Uddin, B. Wosnitzer, N. Takahashi, E. Alhaj, A. Legasto, B. Abiri, K. Elsaban, T. El Khouly, T. El Kammash, A. Al Ghamdi, B. Kyung Deok, K. Bon Seung, Y. Sang Geun, D. Chang Min, and M. Gwan Hong
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O. Barthelemy, J. Silvain, D. Brieger, A. Bellemain-Appaix, G. Cayla, F. Beygui, R. Lancar, J. P. Collet, A. Mercadier, G. Montalescot, K. S. Cha, Y. H. Nam, J. H. Kim, S. Y. Park, T. H. Park, M. H. Kim, Y. D. Kim, H. C. Lee, M. S. Ahn, T. J. Hong, R. Blanco, F. Blanco, J. Szarfer, A. Garcia Escudero, G. Gigena, J. Gagliardi, A. Rodriguez, R. Sarmiento, S. Affatatto, M. Riccitelli, A. Petris, M. D. Datcu, C. Pop, M. Radoi, C. Arsenescu-Georgescu, I. Petrescu, L. Petrescu, L. Serban, E. Nechita, G. Tatu-Chitoiu, M. Dorobantu, I. Benedek, E. Craiu, C. Sinescu, D. D. Ionescu, C. Ginghina, B. Minescu, A. Izzo, P. Mantovani, L. Tomasi, L. Dall'oglio, S. Bonatti, R. Rosiello, M. Romano, F. Agostini, R. Zanini, Z. Y. Zhao, Y. J. Wu, J. J. Li, Y. J. Yany, H. Y. Qian, Y. D. Tang, A. T. Timoteo, A. Toste, A. Lousinha, R. Ramos, J. A. Oliveira, M. L. Ferreira, R. C. Ferreira, C. Cabades, J. L. Diez Gil, P. Aguar, D. Sanmiguel, A. Lopez-March, R. Marmol, L. Guerra, V. Girbes, J. Ferrando, A. Rincon De Arellano, L. Patricio, M. Blondal, T. Ainla, T. Marandi, J. Eha, M. M. Oliveira, M. N. Silva, P. S. Cunha, J. Feliciano, S. Silva, J. Kanovsky, P. Kala, J. Parenica, M. Poloczek, K. Prymusova, L. Kubkova, J. Spinar, D. Olinic, C. Homorodean, M. Ober, M. Olinic, C. Andrioaia, A. Condac, M. Masmoudi, B. Berdaoui, S. Labidi, C. Tapia Ballesteros, C. Hernandez Luis, M. G. Sandin, J. M. Vegas, R. Andion, N. Martinez, I. A. Gonzalez, M. Alvarado, I. J. Amat, J. A. San Roman, M. J. Garcia Gonzalez, E. Arroyo Ucar, C. Hernandez Garcia, M. Dorta Martin, F. Marrero Rodriguez, R. Dragu, M. Kapeliovich, H. Hammerman, D. Silva, N. Cortez-Dias, C. Jorge, J. Silva Marques, P. Carilho Ferreira, S. Robalo Martins, M. Almeida Ribeiro, C. Calisto, M. Fiuza, M. G. Lopes, P. Milicevic, M. Panic, I. Stankovic, D. Milicevic, T. Kalezic, S. Kafedzic, I. Ilic, M. Cerovic, B. Putnikovic, A. Neskovic, D. Rott, D. Leibowitz, Z. Monhart, J. Reissigova, H. Grunfeldova, P. Jansky, B. Valente, I. Villanueva Benito, I. Solla, E. Paredes, O. Diaz Castro, F. Calvo, J. A. Baz, A. Iniguez, A. Aleksova, R. Gerloni, R. Belfiore, C. Carriere, G. Barbati, E. Fabris, F. Possa, D. Nait, M. Milo, G. Sinagra, N. Marques, J. Mimoso, V. Gomes, R. M. Agra Bermejo, E. A. A. Emad Abu Assi, S. R. R. Sergio Raposeiras Roubin, P. C. G. Pilar Cabanas Grandio, C. P. G. Carlos Pena Gil, J. M. G. A. Jose Maria Garcia Acuna, J. R. G. J. Jose Ramon Gonzalez Juanatey, M. J. Daly, P. Scott, C. G. Owens, A. Tomlin, B. Smith, A. A. J. Adgey, L. R. Alvarez-Contreras, U. Juarez, A. Altamirano, A. Arias, A. Alvarez-San Gabriel, H. Gonzalez-Pacheco, C. Martinez-Sanchez, M. Rahnavardi, M. Keshtkar-Jahromi, H. Vakili, S. Gholamin, S. M. Razavi, T. Gilis-Januszewski, K.- P. Mellwig, M. Wiemer, J. Gilis-Januszewski, A. Peterschroeder, J. Koerfer, D. Horstkotte, M. Vrsalovic, B. Getaldic, N. Vrkic, H. Pintaric, S. Khan, B. Wasan, L. Moretti, P. Grossi, S. Silenzi, M. Testa, L. Candelori, L. N. Clementi, M. Forlini, L. Lando, M. L. Pezzuoli, P. Corradetti, G. Leurent, P. Y. Pennec, E. Filippi, B. Moquet, J. P. Hacot, P. Druelles, A. Rialan, G. Rouault, I. Coudert, H. Le Breton, S. Gevaert, F. Tromp, E. Vandecasteele, F. De Somer, Y. Van Belleghem, S. Bouchez, F. Martens, I. Herck, M. De Pauw, O. Ludka, M. Sepsi, R. Miklik, L. Dusek, D. Tomcikova, J. M. Garcia-Acuna, P. Aguiar-Souto, S. Raposeiras Roubin, R. Agra-Bermejo, M. Jacquet, E. Abu-Assi, J. R. Gonzalez-Juanatey, A. Ibatov, R. Labrova, R. Karlik, P. Lokaj, Q. She, S. B. Deng, S. H. Huang, L. J. Gu, J. I. A. N. Rong, Z. K. Wu, Y. Li, J. Zhang, L. Parascan, A. Campanile, L. Spinelli, G. Santulli, M. Ciccarelli, S. De Gennaro, E. Assante Di Panzillo, B. Trimarco, G. Iaccarino, E. Bobescu, G. Datcu, D. Dobreanu, B. Doka, J.- C. Charniot, C. Cosson, J. P. Albertini, R. Bittar, P. Giral, C. Cherfils, E. Guillerm, D. Bonnefont-Rousselot, A. Rusali, L. Cojocaru, I. Parepa, T. Koizumi, S. Iida, J. Sato, T. Kikutani, T. Muramatsu, S. Nishimura, N. Komiyama, W. P. Lee, B. B. Ong, K. Haralambos, D. Townsend, J. A. E. Rees, E. J. Williams, J. P. Halcox, I. Mcdowell, M. Damjanovic, G. Koracevic, D. Djordjevic-Radojkovic, M. Pavlovic, N. Krstic, S. Ciric-Zdravkovic, A. Stojkovic, Z. Perisic, S. Apostolovic, A. Faustino, L. Seca, S. Barra, F. Caetano, R. Providencia, J. Silva, P. Gomes, G. Costa, M. Costa, A. Leitao-Marques, A. L. Volkova, G. P. Arutyunov, N. A. Bylova, I. I. Dayter, Y. T. F. N. Jao, C. C. Fang, Y. Chen, C. L. Yu, S. P. Wang, J. Valencia, P. Perez-Berbel, J. M. Ruiz-Nodar, J. Pineda, P. Bordes, M. Quintanilla, V. Mainar, F. Sogorb, N. Santos, M. Serrao, H. Cafe, B. Silva, R. Oliveira, G. Caires, A. Drumond, J. Araujo, R. A. Providencia, P. L. Gomes, J. R. Pais, P. Mota, A. M. Leitao-Marques, S. Farhan, R. Jarai, I. Tentzeris, B. Vogel, M. K. Freynhofer, J. Wojta, K. Huber, M. Poli, P. Trambaiolo, F. Corsi, M. De Luca, M. Mustilli, V. Lukic, M. Simonetti, G. Ferraiuolo, M. Lettino, G. Casella, M. R. Conte, L. De Luca, G. Geraci, R. Ceravolo, A. Pani, G. Fradella, A. Schratter, H. Thiele, T. Klemm, K. Demmin, D. Lehmann, M. Mende, G. Schuler, U. Pittl, A. Chernova, S. U. Nikulina, T. Naruke, T. Inomata, T. Yanagisawa, E. Maekawa, T. Mizutani, H. Shinagawa, M. Nishii, I. Takeuchi, H. Takehana, T. Izumi, C. Paulo, J. Mascarenhas, M. Patacho, J. Pimenta, P. Bettencourt, S. Nardai, G. Y. Szabo, B. Berta, I. Edes, B. Merkely, J. Delgado Silva, R. Baptista, R. Faria, J. Trigo, P. Gago, G. Gheorghe, I. T. Nanea, A. Cristea, S. Almarichi, H. Martins, F. Saraiva, E. Jorge, P. L. Mendes, P. Monteiro, S. Costa, F. Franco, L. A. Providencia, T. Nanea, G. S. Gheorghe, S. Visan, N. Paun, R. Gaber, R. Delewi, R. Nijveldt, H. A. De Bruin, A. Hirsch, A. Van Der Laan, B. J. Bouma, J. P. G. Tijssen, A. C. Van Rossum, F. Zijlstra, J. J. Piek, H. Rus, M. Donea, C. Ciurea, G. Ifteni, G. Casolo, M. Chioccioli, M. Magnacca, J. Del Meglio, A. Comella, M. Baratto, J. Lera, L. Salvadori, C. Tessa, C. Vignali, Z. Keca, T. Momcilov Popin, G. Panic, R. White, F. Mateen, A. Weaver, Y. Agmon, E. Okisheva, D. Tsaregorodtsev, V. Sulimov, I. J. Amat Santos, C. Hernandez, C. Tapia, A. Campo, D. Fredman, L. Svensson, M. Rosenqvist, S. Tadel-Kocjancic, P. Radsel, R. Knafelj, V. Gorjup, M. Noc, E. Zima, Z. S. Jenei, E. Kovacs, I. Osztheimer, L. Molnar, A. Horvath, D. Becker, L. Geller, R. Maggi, T. Furukawa, V. Viscardi, M. Brignole, S. R. N. Leal, H. Dores, I. Rosario, J. Monge, M. J. Carvalho, I. Arroja, A. Leitao, C. Fonseca, A. Aleixo, A. Silva, S. Keuleers, P. Herijgers, M. C. Herregods, W. Budts, C. Dubois, B. Meuris, P. Verhamme, W. Flameng, F. Van De Werf, T. Adriaenssens, H. Badran, M. Elnoamany, T. Lolah, C. Olariu, C. Macarie, M. A. H. Mollik, A. I. Hassan, T. K. Paul, M. Z. Haque, R. Jahan, M. Rahmatullah, M. A. Khatun, M. T. Rahman, M. H. Chowdhury, J. Bustamante Munguira, E. Tamayo, I. Garcia-Cuenca, E. Bustamante, J. Gualis, M. L. Gomez-Martinez, S. Florez, J. I. Gomez-Herreras, R. Ramirez Rodriguez, A. M. Ramirez Rodriguez, M. A. Garcia-Bello, E. Hernadez Ortega, E. Caballero Dorta, A. Garcia Quintana, V. Piro Mastraccio, A. Medina Fernandez Aceytuno, E. Assanelli, M. De Metrio, M. Rubino, G. Lauri, A. Cabiati, J. Campodonico, M. Grazi, M. Moltrasio, I. Marana, G. Marenzi, M. Lovlien, B. Schei, R. Picon-Heras, C. Acebal, J. C. Garcia Rubira, D. Vivas Balcones, I. Nunez-Gil, B. Ruiz-Mateos, B. Ibanez, A. Fernandez-Ortiz, V. D. Vintila, O. A. Enescu, C. I. Stoicescu, C. Udroiu, M. Cinteza, G. Tatu - Chitoiu, D. Vinereanu, C. Fresco, M. De Biasio, D. Muser, R. Sappa, G. Morocutti, G. Bernardi, A. Proclemer, B. Fontanella, A. Affatato, C. Ciccarese, M. Sacchini, M. Volpini, F. Bianchetti, G. Verzura, L. Dei Cas, R. Pudil, V. Blaha, J. Vojacek, I. Paraskevaidis, I. Ikonomidis, J. Parissis, C. Papadopoulos, V. Stasinos, V. Bistola, M. Anastasiou-Nana, M. Shochat, A. Shotan, M. Kazatsker, V. Gurovich, A. Asif, E. Noiman, Y. Levy, D. Blondhaim, P. Rabinovich, S. Meisel, S. Petrovic, J. Glasnovic, M. Tomasevic, D. Sakac, S. Obradovic, O. Londono Sanchez, S. Pacreu, L. Torres, G. Mihaylov, G. M. Shaban, E. Trendafilova, V. Krasteva, T. S. Mudrov, J. P. Didon, V. Panageas, N. Vlachos, A. Pernat, I. Radan, H. Mozina, P. Pepi, F. Cionini, N. Baccaglioni, A. Viertel, J. Havers, G. Ballard, G. Groenefeld, L. M. Branco, L. Ferreira, A. Fiarresga, L. Lettieri, A. Reggiani, R. Juarez Prera, G. Blanco Palacios, A.- C. Martin, S. Manzo Silberman, A. Chaib, O. Varenne, P. Allouch, E. Salengro, A. Jegou, O. Margot, C. Spaulding, A. Diego, A. De Miguel, C. Cuellas, E. Fraile, J. Martin, B. Vega, R. Bangueses, F. Fernandez-Vazquez, A. Perez De Prado, S. Leal, M. J. Correia, J. C. Monge, J. Abecasis, C. Garcia-Garcia, I. Subirana, J. Sala, J. Bruguera, V. Valle, G. Sanz, M. Fiol, F. Aros, J. Marrugat, R. Elosua, S. N. C. Barra, A. Leitao Marques, Y. J. Yang, B. Xu, G. Y. Song, R. L. G, A. Aleksic, P. Serpytis, K. Rucinskas, A. Kalinauskas, N. Karvelyte, C. I. Santos De Sousa, S. Ferreira, J. Calaca, N. Lousada, R. Palma Reis, D. M. Gualandro, L. F. B. C. Seguro, F. G. M. Braga, O. M. Silvestre, R. L. Lage, J. Fabri, M. T. Oliveira, J. A. Urbano Moral, J. Torres Llergo, R. Solanilla Rodriguez, A. Sanchez Gonzalez, A. Martinez Martinez, C. A. Den Uil, W. K. Lagrand, M. Van Der Ent, L. S. D. Jewbali, J. M. Cheng, P. E. Spronk, M. L. Simoons, C. Mornos, D. Dragulescu, A. Ionac, J. Guardado, O. Azevedo, M. Fernandes, F. Canario-Almeida, V. Sanfins, A. Pereira, J. Almeida, V. U. Kaplunova, Y. N. Belenkov, E. V. Privalova, A. A. Fomin, A. Y. Suvorov, A. Goodkova, M. G. Rubakova, I. A. Kuznetsova, E. N. Semernin, F. Keshavarzi, J. Kojuri, V. M. Mikhailov, I. V. Vezhenkova, A. Y. A. Goodkova, I. Pavlovic, M. Schwarz, G. Jakl, P. Smetana, T. Perkmann, A. Mayr, J. Mair, G. Klug, M. Schocke, T. Trieb, W. Jaschke, O. Pachinger, B. Metzler, L. Bronze Carvalho, J. Azevedo, M. L. Andrade, M. J. Relvas, J. Coucello, G. Morais, M. Seabra, F. Afamefule, M. Luaces Mendez, R. Teijeiro-Mestre, I. J. Nunez-Gil, N. Leco-Gil, E. Madronal-Cerezo, I. Zannin, J. Ruiz, M. A. Orynchak, I. I. Vakalyuk, I. P. Vakalyuk, A. Berezin, T. Panasenko, Y. Cavusoglu, A. Cavusoglu, I. Unluoglu, M. Tek, C. Demirustu, B. Gorenek, M. Unalacak, A. Birdane, F. Yuksel, N. Ata, J. P. J. Halcox, A. Beyaztas, E. Entok, I. Uslu, A. Schaefer, U. Flierl, N. Seydelmann, J. Bauersachs, L. Calmac, S. Marinescu, G. Tatu Chitoiu, A. G. Fruntelata, S. Hamdi, Y. Maazoun, A. Neji, O. Farhat, M. Majdoub, K. Ben Hamda, F. Maatouk, S. M. Balanescu, I. Nedelciuc, D. Deleanu, F. Ortan, S. Mot, P. R. Sinnaeve, S. Moreels, M. Coosemans, T. Vydt, W. Desmet, D. Tobing, R. Rifnaldi, D. Juzar, I. Firdaus, S. Dharma, I. Irmalita, H. Kalim, R. Bejiqi, R. Retkoceri, H. Bejiqi, L. Kryeziu, M. Kelmendi, S. H. Borovci, S. M. Victor, A. Gnanaraj, R. Deshmukh, A. S. Mullasari, M. Yahalom, R. S. Kaiyal, N. Roguin, J. Bornstein, S. Atar, R. Farah, L. F. Seca, A. M. Leitao Marques, R. Margato, P. Sousa, H. Ribeiro, L. Rocha, A. Correia, J. I. Moreira, H. C. Carvalho, M. Afifi, N. Abed, A. Suarez-Barrientos, D. Vivas, F. Castro-Ferreira, E. Franco, J. C. Garcia-Rubira, V. Fuster, C. Macaya, B. Ibanez Cabeza, S. Salinger, D. Milic, T. Stanojlovic, T. Kostic, M. A. Khan, F. Vrapi, K. Naeem, J. Davar, K. Hristova, G. Pencheva, R. Radeva, S. Milanov, A. Fareed, M. Oraby, G. M. Nasr, F. Maklady, P. Dupouy, J. T. Sorensen, C. J. Terkelsen, J. F. Lassen, S. Trautner, E. F. Christensen, T. T. Nielsen, H. E. Botker, H. R. Andersen, K. A. Thygesen, L. Checco, T. Usmiani, P. L. Sbarra, M. Boffini, R. Saviolo, C. Grasso, F. Conrotto, M. Marchetti, M. Rinaldi, S. Marra, F. Moscoso Costa, J. Ferreira, L. Raposo, C. Aguiar, M. Trabulo, J. A. Silva, V. Marques, A. Swiatkowski, J. Kowalczyk, R. Lenarczyk, P. Chodor, G. Honisz, T. Was, M. Swierad, B. Sredniawa, L. Polonski, Z. Kalarus, A. S. Postadzhiyan, H. Velinov, V. Velchev, D. Hazarbasanov, M. Apostolova, B. Finkov, M. Petrovic, A. Jovelic, T. Canji, I. Srdanovic, T. Popov, M. Golubovic, K. Pavlovic, N. Cemerlic-Adjic, J. Bro-Jeppesen, J. Kjaergaard, M. C. Wanscher, S. L. Nielsen, L. S. Rasmussen, C. Hassager, M. Khan, E. Crolla, H. Morley, L. Akeroyd, Y. Beaini, C. Morley, R. H. Bekeredjian, U. Krumsdorf, W. Rottbauer, H. A. Katus, S. Pleger, A. Botelho, N. Quintal, P. Faria, S. Gomes, J. C. Roussel, T. Senage, C. Perigaud, O. Habash, M. Michel, M. Treilhaud, P. Despins, J. N. Trochu, O. Baron, D. Duveau, A. N. Kitsiou, K. Giannakopoulos, G. Papadimitriou, S. Karas, Z. Babic, V. Nikolic Heitzler, D. Milicic, M. Bergovec, M. Raguz, J. Mirat, M. Strozzi, Z. Plazonic, L. Giunio, R. Steiner, M. Freynhofer, I. Brozovic, V. Bruno, L. Leherbauer, M. Djurkovic, M. Willheim, W. Huebl, S. Hahne, I. Kozanli, K. Kalla, A. Geppert, G. Unger, A. F. Simoes Marques Assuncao Caetano, C. Faustino, A. Ariza Sole, J. C. Sanchez Salado, V. Lorente Tordera, V. Martinez Garcia, J. Salazar Mendiguchia Y Garcia, J. A. Gomez Hospital, J. Maristany Daunert, F. J. Berdejo Gago, E. Esplugas Oliveras, A. Brzozowska-Czarnek, A. Urbanik, N. Kakouros, S. Kakouros, J. Lekakis, J. Rizos, D. Kokkinos, J. Venevtseva, A. Melnikov, M. Valiahmetov, T. Gomova, I. Perelomova, J. J. Ferrer Hita, F. Bosa-Ojeda, A. Sanchez-Grande-Flecha, G. Yanes-Bowden, M. J. Vargas-Torres, A. Rodriguez-Gonzalez, C. Rubio-Iglesias-Garcia, A. Dominguez-Rodriguez, C. Enjuanes-Grau, F. Marrero-Rodriguez, A. I. Suceveanu, A. Suceveanu, L. Mazilu, L. Alexandrescu, E. Dumitru, V. Miu, V. Jitari, F. L. Voinea, K. P. Balachandran, R. Schofield, R. Sankaranarayanan, K. Helm, C. Crowe, R. Singh, J. Mcdonald, M. J. Chuen, M. Kobusiak-Prokopowicz, M. Preglowska, A. Mysiak, T. Doi, T. Sakoda, T. Akagami, T. Naka, T. Tsujino, T. Masuyama, M. Ohyanagi, N. Kume, H. Mitsuoka, K. Hayashida, M. Tanaka, L. M. Biasucci, R. Della Bona, G. Biasillo, M. Leo, M. Zaninotto, M. Plebani, F. Crea, R. Dellabona, B. Gok, A. Unalir, B. Timuralp, N. Nikulina, S. S. Yakushin, G. I. Furmenko, S. A. Akinina, R. Ingrid, L. Bronze, S. Djambazov, A. Zhivkov, I. Maznev, M. Ingeliev, R. Slavov, N. Cvetkova, V. Patarinski, L. Groch, J. Horak, N. Dimitrov, H. G. Hayrapetyan, P. Cabanas-Grandio, C. Pena-Gil, N. A. Mc Keag, C. J. Mc Cann, C. Cardwell, I. S. Young, N. Mikhalchikova, N. Burova, M. Zaccaria, P. Palmisano, V. Palumbo, M. M. Ciccone, S. Favale, K. C. Chen, W. H. Yin, J. H. Liu, S. Goncalves, J. F. Santos, P. Amador, L. N. Soares, K. Zahidova, F. Guliyev, N. Zahidov, P. Carrilho-Ferreira, J. S. Marques, J. Carvalho De Sousa, H. Uthoff, C. Thalhammer, M. Potocki, T. Reichlin, M. Noveanu, M. Aschwanden, D. Staub, N. Arenja, T. Socrates, C. Mueller, Y. Zhao, X. Wu, Q. Xue, L. Gao, H. Lin, S. Wang, K. Watanabe, A. Kawamura, T. Seko, A. Omura, S. Sakabe, A. Kasai, A. V. Starodubova, G. Storozhakov, O. Kisliak, F. Hautieva, M. Tursheva, N. Fedotova, R. C. Di Maio, J. Mclaughlin, J. D. Allen, J. M. C. Anderson, H. Khaled Nagi, O. Tayeh, W. Farok, A. Mousa, P. Neuzil, J. Skoda, J. Petru, L. Sediva, S. Kralovec, F. Holy, K. Holdova, P. Jehlicka, P. Plasil, V. Y. Reddy, S. Alabakovska, D. Labudovic, S. Jovanova, K. Tosheska, M. Alabakovski, K. Jeevaratnam, S. P. Tee, Y. Zhang, L. Guzadhur, I. S. Gurung, R. Duehmke, A. A. Grace, M. Lei, C. L. Huang, Y. Ishibashi, M. Yamauchi, Y. Akashi, H. Musha, F. Miyake, T. Hnatek, L. Kamenik, P. Sedlon, J. Luxova, B. Steuerova, J. Skvaril, M. Cernohous, M. Zavoral, N. Ratkovic, N. R. Nemanja Djenic, A. J. Aleksandra Jovelic, S. O. Slobodan Obradovic, B. G. Branko Gligic, E. Kletsiou, M. Giannakopoulou, E. Bozas, E. K. Iliodromitis, E. D. E. Papathanassoglou, M. Anton, G. Anton, M. Muraru, S. Salinger Martinovic, M. Radosavljevic, D. Stanojevic, M. Zivkovic, T. Pessoa, N. Aspromonte, C. Ronco, M. Tubaro, M. Santini, F. Colivicchi, A. Aiello, D. Cruz, A. Anzoletti Boscolo, G. Vianello, R. Valle, A. Parspour, S. Watkins, D. Datta, A. G. Nikishin, M. M. Pirnazarov, T. A. Nurbaev, Z. Motovska, M. Fischerova, P. Osmancik, M. Maly, P. Widimsky, E. Pavli, A. Dibra, J. Mehilli, L. Dibra, A. Schoemig, A. Kastrati, P. Carmo, M. Almeida, R. Teles, P. Goncalves, J. Brito, F. D'ascenzo, A. Gonella, G. Longo, A. Pullara, C. Moretti, F. Sciuto, P. Omede', G. Biondi Zoccai, G. P. Trevi, I. Sheiban, H. M. Cafe, D. Pereira, D. Freitas, D. Ortiz Berbel, J. M. Rabasa Baraibar, A. M. Leone, A. De Caterina, A. Aurelio, A. Sciahbasi, E. Lioy, C. Trani, F. Burzotta, I. Porto, A. G. Rebuzzi, K. Trusinskis, D. Juhnevica, K. Strenge, D. Sondore, I. Kumsars, S. Jegere, I. Narbute, A. Grave, I. Zakke, A. Erglis, C. Ferrari, A. L. Bartorelli, M. Saeed, D. Cozma, S. Pescariu, S. I. Dragulescu, H. S. Kamal, A. Abdelfattah, A. M. Abdelbary, H. Elassar, A. Naggar, M. Khaled, A. M. Fareed, J. M. Pernes, J. C. Gaux, M. W. Prull, B. Sasko, H. Wirdemann, A. Bittlinsky, T. Butz, H. J. Trappe, M. Perazzolo Marra, L. Cacciavillani, A. Marzari, M. De Lazzari, R. Turri, P. China, F. Corbetti, S. Iliceto, L. L. Stazhadze, E. A. Spiridonova, N. A. Bulanova, A. A. Ermolaev, L. Savic, I. Mrdovic, G. Krljanac, J. Perunicic, M. Asanin, R. Lasica, M. Matic, Z. Vasiljevic, M. Ostojic, M. Tichy, C. Andrys, A. Conti, C. Poggioni, G. Viviani, F. Bulletti, V. Boni, M. Luzzi, S. Vicidomini, M. Donati, B. Del Taglia, R. Pini, O. Sousa, R. Fontes-Carvalho, D. Caeiro, N. Dias Ferreira, G. Silva, E. Pereira, J. Ribeiro, A. Albuquerque, V. Gama Ribeiro, M. Murai, Y. Takeda, T. Shinmyo, J. Tanigawa, H. Hazui, T. Nakakohji, Y. Ohishi, M. Hoshiga, T. Ishihara, T. Hanafusa, J. Belohlavek, V. Rohn, J. Kunstyr, M. Lips, M. Semrad, F. Mlejnsky, J. Tosovsky, A. Linhart, J. Lindner, Z. Sablik, A. Samborska-Sablik, J. Drozdz, W. Gaszynski, M. M. Izquierdo-Gomez, R. Juarez-Prera, G. Blanco-Palacios, R. Lakhdar, M. Drissa, B. Jedaida, H. Drissa, F. Sampaio, H.- T. Hsin, J.- H. Huang, K.- M. Chiu, Z.- S. Chen, P.- C. Lin, L.- Y. Chen, S.- H. Chu, I. Efthimiadis, P. Skendros, A. Sarantopoulos, P. Boura, A. M. Van Der Laan, P. A. Van Der Vleuten, M. Klees, J. G. P. Tijssen, B. E. Backus, A. J. Six, J. H. Kelder, A. Mosterd, E. G. Mast, T. P. Mast, R. Braam, R. Tio, R. Veldkamp, P. A. Doevendans, N. Paarup Dridi, L. Holmvang, T. Engstroem, S. Rekik, J. Brunet, F. X. Hager, G. Bayet, L. Meille, J. M. Quatre, J. Sainsous, P.- H. Chu, C.- H. Tang, N. Pogosova, I. E. Koltunov, I. D. Sapunova, V. A. Vigodin, R. Uhliar, A. Schmidt, B. Brockmeyer, A. Suzuki, Y. Eki, H. Higuchi, A. Yukawa, R. Yamauchi, Y. Sato, Y. Endo, J. Salazar Mendigucha Garcia, S. Homs Vila, A. Cequier Fillat, R. Andion Ogando, M. Sandin Fuentes, J. M. Vegas Valle, I. A. Gonzalez Garcia, I. A. Duro Aguado, A. J. Palomino Doza, I. Gomez Salvador, J. A. San Roman Calvar, T. M. Mamarasulov, L. Todorovic, Z. C. H. Cherneva, S. D. Denchev, K. Heltai, A. Boytsov, N. N. Nikulina, D. Zanna, V. Marangelli, C. Caiati, R. Picon Heras, M. J. Loureiro, I. Urazovskaya, D. Vinogradova, E. Vasilieva, A. Shpektor, E. Conti, M. B. Musumeci, F. M. Lauri, E. Dito, M. De Giusti, A. Lallo, D. Fusco, M. Davoli, M. Volpe, C. Autore, H. Gamra, Z. Dridi, M. Hassine, F. Addad, I. Gherissi, A. Reda, M. Mahjoub, S. Bouraoui, M. Abdennadher, F. Betbout, P. M. F. P. Mota, J. D. Silva, R. Jankovic Tomasevic, V. Djordjevic, D. Djordjevic Radojkovic, A. Scafa Udriste, A. Fruntelata, E. Gainoiu, S. Bogdan, D. Zamfir, C. Teodorescu, M. Guran, D. Constantinescu, A. Konopka, M. Banaszewski, I. Wojtkowska, J. Stepinska, J. V. Vidergold, I. V. Osipova, T. V. Tavrovskaya, J. V. Galkina, A. V. Timofeev, R. I. Vorobyov, E. N. Vorobyova, L. Matos, A. C. C. Carvalho, W. Oliveira, F. Cintra, D. Poyares, M. Andersen, R. Martins, S. Tufik, P. Ostadal, J. Brada, S. Horakova, M. Mlcek, V. Hrachovina, O. Kittnar, I. V. Gorudko, I. V. Buko, S. N. Cherenkevich, L. Z. Polonetsky, V. Y. Plotkin, M. A. Timoshina, S. V. Azanchevskaya, N. N. Chromov-Borisov, A. Vorlat, L. Snoep, M. J. Claeys, C. J. Vrints, A. Palazzuoli, M. Caputo, I. Quatrini, A. Calabro, G. Antonelli, M. S. Campagna, B. Franci, R. Nuti, A. Maisel, M. Negrini, T. Minora, P. Marino, R. Seregni, E. Tavlueva, O. Barbarash, L. Barbarash, T. Janota, J. Kudlicka, K. Malik, D. Wichterle, J. Hradec, R. Body, S. D. Carley, G. Mcdowell, M. Nuttall, C. Wibberley, M. France, J. K. Cruickshank, K. Mackway-Jones, M. Leon, C. Cozma, F. Mitu, D. R. Almeida, C. B. Dias, I. Burazor, M. Burazor, M. Krstic, M. Lazovic, M. Vukmanovic, J. Djordjevic, Z. Radovanovic, D. Ilic, P. Bosnjakovic, A. C. Ferreira, P. S. Mateus, P. Fontes, T. Teixeira, G. Conte, A. Menozzi, E. Solinas, M. G. Bolognesi, I. Tadonio, F. Mantovani, A. Cattabiani, L. Vignali, D. Ardissino, O. Tautu, A. Alexandrescu, R. Niculescu, R. Jankovic, N. Bozinovic, C. Santos, F. Costa, G. Cardoso, I. Correia, K. Fountoulaki, S. Kastellanos, E. Voltirakis, A. Kokotos, C. Michalakeas, K. Kontsas, K. Hasioti, E. T. Iliodromitis, M. G. Sandin Fuentes, E. Zatarain Nicolas, N. Martinez Uruena, M. Alvarado Montes De Oca, V. Dytrych, T. Kovarnik, O. Smid, A. Kral, A. G. Aroutunov, S. Intwala, I. Jegere, H. S. H. Shaalan, Z. Pagava, R. Agladze, R. Shakarishvili, N. Sharashidze, L. Gujejiani, G. Saatashvili, T. Z. Katova, V. Kostova, Y. Simova, S. Vukotic, S. Rafajlovski, R. Romanovic, N. Antonijevic, B. Gligic, M. Hutyra, T. Skala, D. Horak, D. Vindis, M. Taborsky, A. Contine, M. Del Pinto, F. Angeli, P. Verdecchia, F. Borgognoni, E. Grikstaite, P. Pantano, G. Ambrosio, C. Cavallini, C. Bonanad, J. Sanchis, V. Bodi, J. Nunez, X. Bosch, M. Heras, M. Pellicer, A. Llacer, L. Adao, M. Oliveira, H. Goncalves, J. Primo, V. Gama, C. Lombardi, M. Metra, S. Bugatti, E. Pasotti, F. Quinzani, M. Adamo, C. Villa, R. Rovetta, A. Manerba, M. Mariani, A. Dushpanova, M. Baroni, E. Cerone, A. Nardelli, J. Gianetti, S. Berti, F. Feliciano, R. Soares, S. Santos, A. Kruger, D. Vondrakova, J. Herget, C. Navarro, N. A. Cromie, J. A. A. Adgey, D. Caeiro Pereira, P. Braga, R. Fontes Carvalho, A. Rodrigues, M. Goncalves, L. Simoes, and K. V. Borisov
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Cardiology and Cardiovascular Medicine - Published
- 2010
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6. Highlights of the 12th International Conference on Nuclear Cardiology and Cardiac CT
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Sharmila Dorbala, Arthur J.H.A. Scholte, and Anastasia N. Kitsiou
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Male ,medicine.medical_specialty ,Internationality ,Cardiac computed tomography ,Cardiology ,Radiation Dosage ,Risk Assessment ,nuclear cardiology ,Myocardial perfusion imaging ,hybrid imaging ,Internal medicine ,Medical imaging ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,cardiac computed tomography ,Societies, Medical ,Multimodal imaging ,advances ,medicine.diagnostic_test ,business.industry ,Left bundle branch block ,Coronary flow reserve ,General Medicine ,Congresses as Topic ,medicine.disease ,Cardiac Imaging Techniques ,Tomography x ray computed ,Spain ,Positron emission tomography ,Positron-Emission Tomography ,Female ,Radiology ,Nuclear Medicine ,Tomography, X-Ray Computed ,Cardiology and Cardiovascular Medicine ,business ,Cardiac magnetic resonance ,Forecasting - Abstract
The 12th International Conference on Nuclear Cardiology and Cardiac CT was held from 3 to 5 May 2015 in Madrid, Spain. In this article, the three Congress Program Committee Chairs summarize selected highlights of the presented abstracts.
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- 2015
7. Serious and potentially life threatening complications of cardiac stress testing: Physiological mechanisms and management strategies
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Anastasia N. Kitsiou, Vasken Dilsizian, Nathan E. Crone, Fadi G. Hage, Henry Gewirtz, Nicholas Paivanas, and Ronald G. Schwartz
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medicine.medical_specialty ,Evidence-Based Medicine ,business.industry ,Vasodilator Agents ,education ,Cardiac stress testing ,Medical school ,Myocardial Ischemia ,Risk Assessment ,humanities ,Family medicine ,Heart Function Tests ,Hypertension ,medicine ,Exercise Test ,Humans ,Radiology, Nuclear Medicine and imaging ,General hospital ,Hypotension ,Cardiology and Cardiovascular Medicine ,Intensive care medicine ,business ,Veterans Affairs - Abstract
a Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD b Department of Medicine (Cardiology Division), Massachusetts General Hospital, Harvard Medical School, Boston, MA c Department of Medicine (Division of Cardiology), University of Rochester Medical Center, Rochester, NY d Department of Cardiology, Sismanoglio Hospital, Athens, Greece e Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham and Birmingham Veterans Affairs Medical Center, Birmingham, AL f Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD g Departments of Medicine (Division of Cardiology) and Imaging Sciences (Nuclear Medicine), University of Rochester Medical Center, Rochester, NY
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- 2015
8. Myocardial blood flow at rest and contractile reserve in patients with chronic coronary artery disease and left ventricular dysfunction
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Anastasia N. Kitsiou, Julio A. Panza, Vasken Dilsizian, Rodolfo V. Curiel, Ellis F. Unger, and Joy M. Laurienzo
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Male ,Inotrope ,medicine.medical_specialty ,Contraction (grammar) ,Rest ,Coronary Disease ,Coronary artery disease ,Ventricular Dysfunction, Left ,Coronary Circulation ,Dobutamine ,Internal medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Myocardial infarction ,Hibernating myocardium ,business.industry ,Blood flow ,Middle Aged ,medicine.disease ,Myocardial Contraction ,Stimulation, Chemical ,medicine.anatomical_structure ,Chronic Disease ,Cardiology ,Female ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Echocardiography, Transesophageal ,Tomography, Emission-Computed ,medicine.drug ,Artery - Abstract
The mechanisms that determine chronic left ventricular dysfunction in coronary artery disease (in particular, critical reductions in coronary artery blood flow leading to hibernating myocardium) may affect the ability of the myocardium to respond to inotropic stimulation with dobutamine. This study was designed to investigate the relationship between resting myocardial blood flow and contractile reserve in patients with coronary artery disease and chronic left ventricular dysfunction.Twenty-three patients (21 men and 2 women; age 61 +/- 9 years) underwent transesophageal echocardiography during infusion of dobutamine (2.5 microg/kg to 40 microg/kg per minute) and positron emission tomography (PET) with 150-water (9 patients) or 13N-ammonia (14 patients). Systolic wall thickening at each dose of dobutamine and resting myocardial blood flow were quantitatively analyzed in 8 anatomically matched regions at mid-ventricular level. Myocardial regions with preserved contraction had higher blood flow compared with regions with basal dyssynergy (0.99 +/- 0.3 vs 0.65 +/- 0.3 mL/min/gm; P.0001). Among myocardial regions with preserved resting contraction, no relation was observed between blood flow and the response to dobutamine (r = 0.06). In contrast, among myocardial regions with diminished resting contraction, a significant correlation was observed between resting blood flow and contractile reserve (r = 0.53; P.0001). The maximum increase in percent systolic wall thickening with dobutamine was 32.8% +/- 14% in regions with normal blood flow, 21.5% +/- 17% in regions with mildly to moderately reduced blood flow, and 10.7% +/- 10% in regions with severely reduced blood flow (P.0001).These findings emphasize the importance of resting myocardial blood flow for the preservation of contractile reserve in patients with coronary artery disease and left ventricular dysfunction. Because a positive inotropic response to dobutamine is more likely to occur in dyssynergic regions with preserved rather than reduced myocardial blood flow, regional perfusion may determine in which circumstances dobutamine echocardiography contributes to the assessment of myocardial viability.
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- 1999
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9. 13N-ammonia myocardial blood flow and uptake
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Arshed A. Quyyumi, Vasken Dilsizian, Anastasia N. Kitsiou, Ronald M. Summers, Stephen L. Bacharach, Marissa L. Bartlett, and G. Srinivasan
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medicine.diagnostic_test ,business.industry ,medicine.medical_treatment ,Blood flow ,medicine.disease ,Revascularization ,Coronary artery disease ,Coronary circulation ,Radionuclide angiography ,medicine.anatomical_structure ,Positron emission tomography ,medicine ,business ,Nuclear medicine ,Cardiology and Cardiovascular Medicine ,Perfusion ,Emission computed tomography - Abstract
OBJECTIVES In this study we determined whether 13N-ammonia uptake measured late after injection provides additional insight into myocardial viability beyond its value as a myocardial blood flow tracer. BACKGROUND Myocardial accumulation of 13N-ammonia is dependent on both regional blood flow and metabolic trapping. METHODS Twenty-six patients with chronic coronary artery disease and left ventricular dysfunction underwent prerevascularization 13N-ammonia and 18F-deoxyglucose (FDG) positron emission tomography, and thallium single-photon emission computed tomography. Pre- and postrevascularization wall-motion abnormalities were assessed using gated cardiac magnetic resonance imaging or gated radionuclide angiography. RESULTS Wall motion improved in 61 of 107 (57%) initially asynergic regions and remained abnormal in 46 after revascularization. Mean absolute myocardial blood flow was significantly higher in regions that improved compared to regions that did not improve after revascularization (0.63 ± 0.27 vs. 0.52 ± 0.25 ml/min/g, p CONCLUSIONS These data suggest that beyond its value as a perfusion tracer, late 13N-ammonia uptake provides useful information regarding functional recovery after revascularization. The parallel relationship among 13N-ammonia, FDG, and thallium uptake supports the concept that uptake of 13N-ammonia as measured from the late images may provide important insight regarding cell membrane integrity and myocardial viability.
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- 1999
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10. [ 18 F]Fluorodeoxyglucose Single Photon Emission Computed Tomography
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Marissa L. Bartlett, Vasken Dilsizian, Claiborne Miller-Davis, G. Srinivasan, Anastasia N. Kitsiou, and Stephen L. Bacharach
- Subjects
Adult ,Male ,medicine.medical_specialty ,Asynergy ,chemistry.chemical_element ,Coronary Disease ,Single-photon emission computed tomography ,Sensitivity and Specificity ,Coronary artery disease ,Ventricular Dysfunction, Left ,Fluorodeoxyglucose F18 ,Physiology (medical) ,medicine ,Humans ,Aged ,Tomography, Emission-Computed, Single-Photon ,Fluorodeoxyglucose ,Ejection fraction ,Receiver operating characteristic ,medicine.diagnostic_test ,business.industry ,Myocardium ,Stroke Volume ,Middle Aged ,medicine.disease ,Thallium Radioisotopes ,ROC Curve ,chemistry ,Thallium ,Female ,Radiology ,Radiopharmaceuticals ,Cardiology and Cardiovascular Medicine ,Nuclear medicine ,business ,Tomography, Emission-Computed ,medicine.drug - Abstract
Background —New high-energy collimators for single photon emission computed tomography (SPECT) cameras have made imaging of positron-emitting tracers, such as [ 18 F]fluorodeoxyglucose ( 18 FDG), possible. We examined differences between SPECT and PET technologies and between 18 FDG and thallium tracers to determine whether 18 FDG SPECT could be adopted for assessment of myocardial viability. Methods and Results —Twenty-eight patients with chronic coronary artery disease (mean left ventricular ejection fraction [LVEF]=33±15% at rest) underwent 18 FDG SPECT, 18 FDG PET, and thallium SPECT studies. Receiver operating characteristic curves showed overall good concordance between SPECT and PET technologies and thallium and 18 FDG tracers for assessing viability regardless of the level of 18 FDG PET cutoff used (40% to 60%). However, in the subgroup of patients with LVEF≤25%, at 60% 18 FDG PET threshold value, thallium tended to underestimate myocardial viability. In a subgroup of regions with severe asynergy, there were considerably more thallium/ 18 FDG discordances in the inferior wall than elsewhere (73% versus 27%, P 18 FDG by SPECT and PET was compared in 137 segments exhibiting severely irreversible thallium defects (scarred by thallium), 59 (43%) were viable by 18 FDG PET, of which 52 (88%) were also viable by 18 FDG SPECT. However, of the 78 segments confirmed to be nonviable by 18 FDG PET, 57 (73%) were nonviable by 18 FDG SPECT ( P Conclusions —Although 18 FDG SPECT significantly increases the sensitivity for detection of viable myocardium in tissue declared nonviable by thallium (to 88% of the sensitivity achievable by PET), it will occasionally (27% of the time) result in falsely identifying as viable tissue that has been identified as nonviable by both PET and thallium.
- Published
- 1998
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11. Comparative Effects of Basic Fibroblast Growth Factor and Vascular Endothelial Growth Factor on Coronary Collateral Development and the Arterial Response to Injury
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Mickey Scheinowitz, Esther Guetta, Everett Hodge, Daisy F. Lazarous, Stephen E. Epstein, Jonathan A. Stiber, Sally Hunsberger, Ellis F. Unger, Matie Shou, Venugopal Thirumurti, Arlene D. Lobo, and Anastasia N. Kitsiou
- Subjects
Male ,Vascular Endothelial Growth Factor A ,medicine.medical_specialty ,Angiogenesis ,Basic fibroblast growth factor ,Collateral Circulation ,Endothelial Growth Factors ,Fibroblast growth factor ,Muscle, Smooth, Vascular ,chemistry.chemical_compound ,Dogs ,Coronary Circulation ,Physiology (medical) ,Internal medicine ,medicine ,Animals ,Lymphokines ,Vascular Endothelial Growth Factors ,business.industry ,Hemodynamics ,Arteries ,Hyperplasia ,Collateral circulation ,medicine.disease ,Surgery ,Vascular endothelial growth factor ,Vascular endothelial growth factor A ,Endocrinology ,chemistry ,Female ,Fibroblast Growth Factor 2 ,Cardiology and Cardiovascular Medicine ,business ,Perfusion - Abstract
Background We have shown that the angiogenic peptides basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF) enhance canine coronary collateral development when administered for ≥4 weeks. bFGF, a pluripotent mitogen of mesodermally derived cells, could theoretically exacerbate neointimal smooth muscle cell hyperplasia, a fundamental component of atherosclerosis. VEGF, an endothelial cell–specific mitogen and vascular permeability factor, could have deleterious effects related to vascular hyperpermeability. The present investigation had two aims: (1) to ascertain whether brief (7-day) systemic arterial treatment with bFGF or VEGF would improve myocardial collateral perfusion and (2) to determine whether these peptides induce neointimal accumulation in vivo. Methods and Results Dogs were subjected to ameroid-induced occlusion of the left circumflex coronary artery and randomized to bFGF 1.74 mg (n=9), VEGF 0.72 mg (n=9), or saline (n=10) as a daily left atrial bolus (days 10 to 16). Additional dogs were randomized to VEGF 0.72 mg (n=6) or saline (n=5); however, treatment was delayed by 1 week. Coincident with the institution of treatment, all dogs underwent balloon denudation injury of the iliofemoral artery. bFGF markedly increased maximal collateral flow but did not exacerbate neointimal accumulation. VEGF had no discernible effect on maximal collateral flow, but it exacerbated neointimal thickening after vascular injury. Conclusions Short-term treatment with bFGF enhanced collateral development without increasing neointimal accumulation at sites of vascular injury. Although VEGF did not increase collateral development as administered in this study, it significantly exacerbated neointimal accumulation. These data provide support for the clinical investigation of bFGF in selected patients with ischemic heart disease.
- Published
- 1996
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12. SPECT gated blood pool imaging-potentials and problems
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Stephen L. Bacharach, Anastasia N. Kitsiou, E. Elliott, P. T. Katsiyiannis, Vasken Dilsizian, C. Barker, E. Unger, M. Pettiford, M.L. Bartlett, J. M. Carson, and W. Smeltzer
- Subjects
Planar Imaging ,Ejection fraction ,medicine.diagnostic_test ,Statistical noise ,business.industry ,Blood flow ,Single-photon emission computed tomography ,medicine.disease ,Imaging phantom ,Gated Blood-Pool Imaging ,Coronary artery disease ,medicine ,Nuclear medicine ,business - Abstract
In recent years, the use of single photon emission computed tomography (SPECT) has been proposed for gated blood pool scans in order to assess left ventricular function. By constructing a beating heart phantom, the authors confined that SPECT may be superior to planar imaging for visual assessment of wall motion defects. Further, in data from five patients with coronary artery disease, a correlation was found between quantitative measures of heart wall defects from SPECT gated blood pool images and the magnitude of PET blood flow defects. Finally, the authors investigated the effects of statistical noise, background and attenuation on ejection fraction and amplitude calculations from SPECT slices. Statistical noise and background were found to produce very small effects while attenuation had a small but measurable effect on the amplitude map and no effect on ejection fraction. >
- Published
- 2002
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13. 13N-ammonia myocardial blood flow and uptake: relation to functional outcome of asynergic regions after revascularization
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A N, Kitsiou, S L, Bacharach, M L, Bartlett, G, Srinivasan, R M, Summers, A A, Quyyumi, and V, Dilsizian
- Subjects
Adult ,Male ,Tomography, Emission-Computed, Single-Photon ,Nitrogen Radioisotopes ,Heart Ventricles ,Coronary Disease ,Gated Blood-Pool Imaging ,Stroke Volume ,Middle Aged ,Magnetic Resonance Imaging ,Thallium Radioisotopes ,Ventricular Dysfunction, Left ,Treatment Outcome ,ROC Curve ,Ammonia ,Fluorodeoxyglucose F18 ,Coronary Circulation ,Myocardial Revascularization ,Humans ,Female ,Blood Flow Velocity ,Aged ,Tomography, Emission-Computed - Abstract
In this study we determined whether 13N-ammonia uptake measured late after injection provides additional insight into myocardial viability beyond its value as a myocardial blood flow tracer.Myocardial accumulation of 13N-ammonia is dependent on both regional blood flow and metabolic trapping.Twenty-six patients with chronic coronary artery disease and left ventricular dysfunction underwent prerevascularization 13N-ammonia and 18F-deoxyglucose (FDG) positron emission tomography, and thallium single-photon emission computed tomography. Pre- and postrevascularization wall-motion abnormalities were assessed using gated cardiac magnetic resonance imaging or gated radionuclide angiography.Wall motion improved in 61 of 107 (57%) initially asynergic regions and remained abnormal in 46 after revascularization. Mean absolute myocardial blood flow was significantly higher in regions that improved compared to regions that did not improve after revascularization (0.63+/-0.27 vs. 0.52+/-0.25 ml/min/g, p0.04). Similarly, the magnitude of late 13N-ammonia uptake and FDG uptake was significantly higher in regions that improved (90+/-20% and 94+/-25%, respectively) compared to regions that did not improve after revascularization (67+/-24% and 71+/-25%, p0.001 for both, respectively). However, late 13N-ammonia uptake was a significantly better predictor of functional improvement after revascularization (area under the receiver operating characteristic [ROC] curve = 0.79) when compared to absolute blood flow (area under the ROC curve = 0.63, p0.05). In addition, there was a linear relationship between late 13N-ammonia uptake and FDG uptake (r = 0.68, p0.001) as well as thallium uptake (r = 0.76, p0.001) in all asynergic regions.These data suggest that beyond its value as a perfusion tracer, late 13N-ammonia uptake provides useful information regarding functional recovery after revascularization. The parallel relationship among 13N-ammonia, FDG, and thallium uptake supports the concept that uptake of 13N-ammonia as measured from the late images may provide important insight regarding cell membrane integrity and myocardial viability.
- Published
- 1999
14. Molecular genetics of Turner syndrome: correlation with clinical phenotype and response to growth hormone therapy
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Tsezou, A Hadjiathanasiou, C Gourgiotis, D Galla, A and Kavazarakis, E Pasparaki, A Kapsetaki, M Sismani, C and Theodoridis, C Patsalis, PC Moschonas, N Kitsiou, S
- Abstract
To correlate the origin of the retained X in Turner syndrome with phenotype, pre-treatment height and response to recombinant human growth hormone (rhGH) therapy, systematic clinical assessment and molecular studies were carried out in 33 Greek children with Turner syndrome and their parents including Is children with 45,X and 15 with X-mosaicism. Microsatellite markers on X chromosomes (DXS101 and DXS337) revealed that the intact X was paternal (Xp) in 15/30 and maternal (Xm) in 15/30 children, while 3/33 families were non-informative. No significant relationship was found between parental origin of the retained X and birth weight/length/gestational age, blepharoptosis, pterygium colli, webbed neck, low hairline, abnormal ears, lymphoedema, short 4th metacarpal, shield chest, widely spaced nipples, cubitus valgus, pigmented naevi, streak gonads, and cardiovascular/renal anomalies. With regard to the children’s pre-treatment height, there was a significant correlation with maternal height and target height in both Xm and Xp groups. No differences were found between Xm and Xp groups and the improvement of growth velocity (GV) during the first and second year of rhGH administration, while for both groups GV significantly improved with rhGH by the end of the first and the second year. To our knowledge. this is the first attempt to correlate the parental origin of Turner syndrome with the response to rhGH therapy.
- Published
- 1999
15. Stress-induced reversible and mild-to-moderate irreversible thallium defects: are they equally accurate for predicting recovery of regional left ventricular function after revascularization?
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Arshed A. Quyyumi, Ronald M. Summers, Anastasia N. Kitsiou, Vasken Dilsizian, G. Srinivasan, and Stephen L. Bacharach
- Subjects
Adult ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Ischemia ,chemistry.chemical_element ,Coronary Disease ,Scintigraphy ,Revascularization ,Ventricular Function, Left ,Coronary artery disease ,Radionuclide angiography ,Physiology (medical) ,Internal medicine ,medicine ,Myocardial Revascularization ,Humans ,cardiovascular diseases ,Postoperative Period ,Thallium ,Radionuclide Imaging ,Aged ,Tomography, Emission-Computed, Single-Photon ,Ejection fraction ,medicine.diagnostic_test ,Vascular disease ,business.industry ,Hemodynamics ,Stroke Volume ,Middle Aged ,medicine.disease ,Prognosis ,Magnetic Resonance Imaging ,chemistry ,Evaluation Studies as Topic ,Chronic Disease ,cardiovascular system ,Cardiology ,Exercise Test ,Female ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background —In patients with coronary artery disease, stress-redistribution-reinjection thallium scintigraphy provides important information regarding myocardial ischemia and viability. Although both reversible and mild-to-moderate irreversible thallium defects retain metabolically active, viable myocardium, we hypothesized that stress-induced reversible thallium defects may better differentiate reversible from irreversible regional left ventricular dysfunction after revascularization. Methods and Results —Twenty-four patients with chronic coronary artery disease underwent prerevascularization and postrevascularization exercise-redistribution-reinjection thallium single photon emission CT, gated MRI, and radionuclide angiography. After revascularization, mean left ventricular ejection fraction increased from 30±9% to 37±13% at rest ( P P P P =NS). Furthermore, when asynergic regions were grouped according to the final thallium content, at 60% threshold value, functional recovery was observed in 83% of regions with reversible defects compared with 33% of regions with mild-to-moderate irreversible defects ( P Conclusions —These findings suggest that although both reversible and mild-to-moderate irreversible thallium defects after stress retain viable myocardium, the identification of reversible thallium defect on stress in an asynergic region more accurately predicts recovery of function after revascularization. Even at a similar mass of viable myocardial tissue (as reflected by the final thallium content), the presence of inducible ischemia is associated with an increased likelihood of functional recovery.
- Published
- 1998
16. Using spatial-temporal images for analysis of gated cardiac tomographic data: The 'M-Mode' revisited
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K. A. Nour, Anastasia N. Kitsiou, J. M. Carson, G. Srinivasan, Vasken Dilsizian, Stephen L. Bacharach, Marissa L. Bartlett, Clara C. Chen, and Irène Buvat
- Subjects
Computer science ,business.industry ,Feature vector ,Representation (systemics) ,Pattern recognition ,Artificial intelligence ,business ,Perfusion - Abstract
Recent advances in SPECT and PET technology permit ECG gating of tomographic cardiac images, allowing simultaneous measurement of 3D cardiac ventricular function with perfusion/metabolism. Extracting indices of regional function from these 4D data sets (3D space + time) remains a challenge. All approaches currently used to quantitate gated tomographic sequences deal separately with the spatial and temporal data. As functional information is based on close coupling between spatial and temporal changes, it could be beneficial to produce an image combining spatial and temporal information. In this paper we describe a method for producing such spatialtemporal images and, using gated FDG PET data, test the ability of these images to improve visual and quantitative assessment of cardiac function. Other potential schemes to make use of the space-time nature of this new representation are also discussed.
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- 1997
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17. Left ventricular ejection fraction: comparison of results from planar and SPECT gated blood-pool studies
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M L, Bartlett, G, Srinivasan, W C, Barker, A N, Kitsiou, V, Dilsizian, and S L, Bacharach
- Subjects
Adult ,Male ,Tomography, Emission-Computed, Single-Photon ,Humans ,Female ,Gated Blood-Pool Imaging ,Heart ,Stroke Volume ,Middle Aged ,Ventricular Function, Left ,Aged - Abstract
Global ejection fraction (EF) from planar gated blood-pool (GBP) imaging is a widely accepted measure of cardiac function. It has been suggested that planar GBP could be replaced by SPECT. In this article, we compare counts-based global EF measured from SPECT and planar images and investigate reasons for discrepancies between the two.Twenty-three subjects were imaged with both planar and SPECT GBP. SPECT short-axis slices were projected to create reprojected images. Reprojected SPECT (rSPECT) images were created in both the true long-axis view and also in a view typical of planar studies (found to be 60 degrees from the true long-axis). Thus, angle of view effects on global EF could be investigated. In addition, we studied the effects of background and attenuation.Long-axis rSPECT EF correlated well with planar EF (r = 0.89) but EF values were significantly higher for rSPECT than for planar (slope = 1.4, intercept = -8 EF units; p0.001). We found that background correction may not be necessary with rSPECT, but neither background nor attenuation explained the observed discrepancy between rSPECT and planar EFs. This discrepancy was found to be caused by atrial overlap in the planar image and disappeared when the SPECT slices were reprojected at the same angle of view as the planar images.Global EF can be easily measured from rSPECT GBP images. Long-axis rSPECT EFs are, however, greater than planar EFs by a factor of 1.4 because atrial overlap causes a significant drop in planar EF in planar images. These results suggest that (long-axis) rSPECT EFs may be more accurate than planar EFs.
- Published
- 1996
18. Putative periodontal pathogens, antibody titres and avidities to them in a longitudinal study of patients with resistant periodontitis
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Denis F. Kinane, T Sigurdsson, J Mooney, WP Holbrook, and N Kitsiou
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Adult ,Male ,medicine.drug_class ,Antibiotics ,Antibody Affinity ,chemical and pharmacologic phenomena ,Antitrichomonal Agents ,Gingival Pocket ,Penicillins ,Aggregatibacter actinomycetemcomitans ,Statistics, Nonparametric ,Immune system ,Metronidazole ,medicine ,Humans ,Avidity ,Longitudinal Studies ,Periodontitis ,General Dentistry ,Porphyromonas gingivalis ,biology ,business.industry ,Amoxicillin ,Middle Aged ,medicine.disease ,biology.organism_classification ,Antibodies, Bacterial ,Otorhinolaryngology ,Immunology ,Chronic Disease ,biology.protein ,Disease Progression ,Female ,Antibody ,business ,medicine.drug - Abstract
OBJECTIVE: To study changes in antibody titres and antibody avidities to putative periodontal pathogens in patients with resistant periodontitis and to compare these findings with the result of culture of these pathogens. SUBJECTS AND METHODS: Patients meeting strict clinical criteria in whom periodontal therapy had failed to prevent disease progression were studied microbiologically and immunologically over a 75-week period. Particular reference was made to the isolation of Actinobocillus actinomycetemcomitons (Aa) and Porphyromonos gingivalis (Pg) together with changes in antibody titres and avidities to these organisms between baseline examination and week 75. RESULTS: Pg was eliminated following antibiotic treatment but metronidazole and amoxycillin therapy failed to remove Aa in all cases. Antibody avidities to these pathogens were higher in patients than in matched controls but no change in avidity was noted during the course of treatment. Most antibody titres were not significantly higher in patients than in controls. CONCLUSIONS: Continued disease progression characterised these patients who, nevertheless, mounted an immune response to the periodontal pathogens but this appeared to be inadequate to stop the disease.
- Published
- 1996
19. Induced electrophysiological isolation of the myocardium prevents ventricular fibrillation
- Author
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S D, Moulopoulos, D A, Sideris, S T, Toumanidis, D P, Karagiannis, E B, Kostis, A B, Kontogiannis, A N, Kitsiou, and H, Deligeorgi-Politi
- Subjects
Electrophysiology ,Electrocardiography ,Dogs ,Evaluation Studies as Topic ,Ventricular Fibrillation ,Cardiac Pacing, Artificial ,Animals ,Laser Therapy - Abstract
to investigate whether an encircling procedure without ventriculotomy, not involving the endocardium, may have a protective effect against ventricular fibrillation (VF), by achieving a physiological rather than anatomic entrenchment.the occurrence of VF was tested by DC application within an area entrenched by a circular "dotted" line formed by LASER (Nd-Yag) point by point applications. The result was compared with that from similar DC applications before the successful LASER entrenchment or beyond the restricted area.16 anaesthetized mongrel dogs, weights 14-20 kg were used.VF occurred 13/118 times by applying DC within the entrenched area and 86/114 times by applying the current outside this area or before the intervention (P less than 0.0005). The pacing threshold was significantly (P less than 0.001) increased within the circumscribed area (4.625 +/- 5.335 vs 0.859 +/- 0.947 mA). The maximal rate at which the ventricles could be driven by pacing at double threshold intensity was not significantly altered by the encircling procedure. Histological examination showed crater-like epicardial destruction with necrosis, loss of myocardial striation, haemorrhage, and polymorphonuclear infiltration, extending about 0.5 cm from the necrotic tissue. The subendocardial area was spared showing only hyperaemia, while the endocardium was intact.Encircling a small area by LASER point by point applications prevents the occurrence of VF when DC is applied within the restricted area, while permitting the conduction of paced beats. The size of the encircled area necessary to this effect is of importance, possibly reflecting the critical mass needed for the occurrence and maintenance of VF.
- Published
- 1991
20. 6.12Pan-Hellenic registry on the strategy used for diagnostic evaluation of patients after an acute ST-elevation myocardial infarction
- Author
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N. Kitsiou and A.N. Anastasia
- Subjects
medicine.medical_specialty ,business.industry ,St elevation myocardial infarction ,Internal medicine ,medicine ,Cardiology ,Radiology, Nuclear Medicine and imaging ,Diagnostic evaluation ,Cardiology and Cardiovascular Medicine ,business - Published
- 2007
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21. Relation between myocardial blood flow and contractile reserve in patients with chronic coronary artery disease and impaired left ventricular systolic function
- Author
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Julio A. Panza, Vasken Dilsizian, Joy M. Laurienzo, Anastasia N. Kitsiou, and Rodolfo V. Curiel
- Subjects
Coronary artery disease ,medicine.medical_specialty ,business.industry ,Internal medicine ,medicine ,Cardiology ,In patient ,Myocardial infarction ,Blood flow ,Systolic function ,Cardiology and Cardiovascular Medicine ,medicine.disease ,business - Published
- 1996
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22. 7.56 Relation between Q-waves and viable myocardium in patients with prior myocardial infarction and left-ventricular dysfunction
- Author
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Christodoulos Stefanadis, Anastasia N. Kitsiou, and Pavlos Toutouzas
- Subjects
medicine.medical_specialty ,business.industry ,Internal medicine ,Cardiology ,Electrocardiography in myocardial infarction ,Medicine ,Radiology, Nuclear Medicine and imaging ,In patient ,Myocardial infarction ,Cardiology and Cardiovascular Medicine ,business ,medicine.disease - Published
- 2001
- Full Text
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23. Can analysis of thallium washout rate from stress to redistribution images obviate the need for reinjection images?
- Author
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Athanasios Theodorakos, Christodoulos Stefanadis, Pavlos Toutouzas, Dimitrios Fasitsas, and Anastasia N. Kitsiou
- Subjects
medicine.medical_specialty ,chemistry ,business.industry ,Internal medicine ,medicine ,Cardiology ,Thallium ,chemistry.chemical_element ,Radiology, Nuclear Medicine and imaging ,Washout rate ,Redistribution (chemistry) ,Cardiology and Cardiovascular Medicine ,business - Published
- 1999
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24. Histomorphologic profile myocardial segments with normal thallium activity in chronic ischemic cardiomyopathy
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Anastasia N. Kitsiou, Jamshid Shirani, G. Srinivasan, Stephen L. Bacharach, L. Ohler, Rebecca Quigg, Vasken Dilsizian, C. Miller-Davis, Ruth Pick, and J. Lee
- Subjects
medicine.medical_specialty ,Ischemic cardiomyopathy ,chemistry ,business.industry ,Internal medicine ,Cardiology ,medicine ,Thallium ,chemistry.chemical_element ,Cardiology and Cardiovascular Medicine ,business - Published
- 1998
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25. RECOVERY OF FUNCTION AFTER REVASCULARIZATION IS DEPENDENT ON PRESERVATION OF MYOCARDIAL BLOOD FLOW
- Author
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Stephen L. Bacharach, Arshed A. Quyyumi, Anastasia N. Kitsiou, Vasken Dilsizian, and Ronald M. Summers
- Subjects
medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Internal medicine ,medicine ,Cardiology ,Radiology, Nuclear Medicine and imaging ,General Medicine ,Function (mathematics) ,Blood flow ,Cardiology and Cardiovascular Medicine ,Revascularization ,business - Published
- 1997
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26. Contribution of coronary vasoconstriction to myocardial blood flow changes induced by physiologic stresses
- Author
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Vasken Dilsizian, Asif Rehman, Arshed A. Quyyumi, Claiborne M. Davis, Anastasia N. Kitsiou, and Stephen L. Bacharach
- Subjects
medicine.medical_specialty ,business.industry ,Internal medicine ,Cardiology ,Medicine ,Coronary vasoconstriction ,Blood flow ,Cardiology and Cardiovascular Medicine ,business - Full Text
- View/download PDF
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