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Paleoxyela nearctica gen. et sp. nov., is described from the upper Eocene of Florissant Formation in Colorado. We placed Paleoxyela gen. nov. in the subfamily Macroxyelinae and the tribe Macroxyelini based on the numerous wing venation characters visible on the specimen. Proxyelia pankowskii gen. et sp. nov. is described from the lower Eocene Fossil Lake deposits of the Green River Formation in Wyoming. We placed Proxyelia gen. nov. in the subfamily Macroxyelinae and the tribe Xyeleciini based on the numerous wing venation characters visible on the specimen. These new records of the family Xyelidae are of particular importance to better understand the past diversity of the clade and propose hypotheses about their diversification. Extant Xyelidae inhabit temperate Northern Hemisphere forests, and most of their larvae feed on conifers, which may explain why they are relatively poorly diversified compared to the other symphytan families. We suggest that the global decline in conifers and the reduced diversity of extant host trees partly explain the diversity of extant Xyelidae. We correlate the biome repartition during the Eocene to that of the extant xyelid.

Because of the scattered pieces of documents both in Khmer and English about the education systems in Cambodia from the prehistoric period to the present, we have tried to collect all the related documents to review and then combined them into one piece. The combined piece from this review makes it a lot easier for all the researchers and readers who want to know about the education system in Cambodia from the past to the present since the piece has highlighted all the stages of the education process in Cambodia along with the review from the look into the history of Cambodia. This article also looks into the future of the education strategic plan (ESP) in Cambodia based on the policy of the Royal Government of the Kingdom of Cambodia and ESP put forth by the Ministry of Education, Youth and Sport (MoEYS).

Background: Concerns have been raised about the inconsistency and quality of pre-service teacher preparation, especially in reading literacy. Mixed-reality simulations can potentially revolutionise initial teacher education by offering realistic, risk-free practice opportunities to master reading practices. Objectives: This study explores pre-service teachers' perceptions of: (1) interacting with avatars; (2) teaching core reading skills, particularly eliciting background information on informational text; and (3) using an action review cycle within a mixed-reality simulation environment. Method: A qualitative exploratory case study design was used in this study in order to document pre-service teachers' perceptions of engaging within a mixed-reality simulation environment. A purposive sampling strategy was used to select participants for this study. Data were analysed using thematic analysis. Results: Findings reveal that pre-service teachers valued interacting with the avatars and appreciated the unique focus on eliciting learners' background knowledge, a core reading practice. They typically teach full lessons with limited genuine engagement during microteaching opportunities, making this an interesting experience. They highlighted the mixed-reality simulation's features, such as pausing, redoing, and receiving immediate feedback. The simulator allowed them to concentrate on skill mastery rather than staging lessons for grades. Conclusion: This study concludes that pre-service teachers' skill development benefits from deliberate practice opportunities designed to enhance complex skills. Mixed-reality simulations could reshape how student teachers are prepared for reading instruction. Contributions: This research contributes to the understanding of pre-service teachers' perspectives on teaching core reading practices in a mixed-reality simulation environment.

Joint reflection amongst teachers is a valuable way to learn from colleagues. The study explored the joint reflection by a primary school mathematics subject team where video-stimulated recall was used as a reflective tool. The research question that guided the study was: what is the influence of joint reflection on the professional development of a mathematics subject team, using video-stimulated recall as a reflective tool? The study leaned on teacher collaboration as a learning context for teachers and used the community of practice as a theoretical framework. The qualitative study used joint video-reflective sessions as data collection instruments where a mathematics subject team of six primary school teachers participated. Lessons of two teachers were video-recorded and played to the subject team and they then jointly reflected on the lessons. The themes that emerged from the data included initial discomfort to share their views about another colleagues' lesson; learner involvement in lessons; strengthening mathematics concepts; and learning from each other. The study found that colleagues learned from each other, that better ways of doing were suggested and that the analysis of the video was like a two-edged sword where those who presented the lesson learned as well as those who watched the lessons.

We investigated the mediating effect of vocational identity in the relationship between mindfulness and career adaptability among graduates in the early career stage. A quantitative survey research design was used to obtain data from 200 participants who were graduates from a higher education institution in South Africa. Variance-based structural equation modelling (SEM) was employed to investigate the conceptual model. Vocational identity acted as a mediator in the relationship between mindfulness and career adaptability. More specifically, a full mediation model was supported. We found that mindfulness does not have a direct relationship with career adaptability. However, being mindful predicts vocational identity, which in turn predicts career adaptability.

The acquisition of passives is well-studied in many languages, with evidence of crosslinguistic differences in the age at which passives are acquired. The aim of this study is to add to the existing knowledge of child acquisition of passives by providing data from Afrikaans and isiXhosa, two under-researched and typologically different languages spoken in South Africa. Comprehension and production data were collected from first language speakers (27 Afrikaans; 29 isiXhosa) from low socioeconomic backgrounds at the beginning and end of their Grade 1 year (aged 6;0 to 7;6). Picture selection and sentence completion tasks of the Receptive and Expressive Activities for Language Therapy were used to collect comprehension and production data, respectively, on short/full passives with actional verbs, reversible passives, and passives containing perceptual and psychological verbs. Comprehension of short passives with actional verbs were fully acquired by the isiXhosa L1 groups and reversible passives were approaching mastery by the beginning of Grade 1, but not the comprehension or production of any other types of passives constructions, by neither the isiXhosa nor the Afrikaans L1 group. By the end of the Grade 1 year, the isiXhosa group had acquired full comprehension and production of all passive types, whereas the Afrikaans group had fully acquired comprehension of both short and full passives with actional verbs but not yet passive production. Language group differences are thought to be related, in part, to differences in passive morphosyntax.

The Konservat-Lagerstätte Menat (Puy-de-Dôme, France) is an outstanding archive of a Paleocene ecosystem, which was deposited in a former maar lake. Excavations during the last century have yielded an extensive flora and fauna record, therefore an overview of the current state of paleontological investigations is given in this paper. Additionally, new results based on excavations from the years 2012 to 2014 are presented. The preservation of organic matter differed strongly between excavation sites, probably influenced by weathering processes. The stratigraphic succession consists mostly of organic-rich clays, intercalated with hard, silicified claystones. In 2013 and 2014 both impression and compression fossils were collected from different outcrops. Compression fossils from organic-rich clays were exceptionally well-preserved and included three-dimensional plant remains. A new database on insect paleobiodiversity was compiled. The occurrence of charcoal in almost all horizons investigated suggests that paleowildfires were frequent during the Paleocene in the vicinity of the paleolake. The results confirm the high potential of the Konservat-Lagerstätte Menat for future paleontological research.

Despite the formidable treatment challenges of pancreatic ductal adenocarcinoma (PDAC), considerable progress has been made in improving drug delivery via pioneering nanocarriers. These innovations are geared towards overcoming the obstacles presented by dysplastic stroma and fostering anti-PDAC immune reactions. We are currently conducting research aimed at enhancing chemotherapy to stimulate anti-tumor immunity by inducing immunogenic cell death (ICD). This is accomplished using lipid bilayer-coated nanocarriers, which enable the attainment of synergistic results. Noteworthy examples include liposomes and lipid-coated mesoporous silica nanoparticles known as silicasomes. These nanocarriers facilitate remote chemotherapy loading, as well as the seamless integration of immunomodulators into the lipid bilayer. In this communication, we elucidate innovative ways for further improving chemo-immunotherapy. The first is the development of a liposome platform engineered by the remote loading of irinotecan while incorporating a pro-resolving lipoxin in the lipid bilayer. This carrier interfered in stromal collagen deposition, as well as boosting the irinotecan-induced ICD response. The second approach was to synthesize polymer nanoparticles for the delivery of mutated KRAS peptides in conjunction with a TLR7/8 agonist. The dual delivery vaccine particle boosted the generation of antigen-specific cytotoxic T-cells that are recruited to lymphoid structures at the cancer site, with a view to strengthening the endogenous vaccination response achieved by chemo-immunotherapy.