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1. May we improve risk stratification for thromboembolic events by combining CHADS2 score with atrial fibrillation presence and duration? Proceedings 16th World Congress in Cardiac Electrophysiology and Cardiac Techniques

Author

G.L. Botto, L. Padeletti, M. Santini, A. Capucci, M. Gulizia, F. Zolezzi, S. Favale, G. Molon, R. Ricci, B. Mariconti, M. Vimercati, G. Corbucci, BIFFI, MAURO, BORIANI, GIUSEPPE, GL.Botto, L.Padeletti, M.Santini, A.Capucci, M.Gulizia, F.Zolezzi, S.Favale, G.Molon, R.Ricci, M.Biffi, B.Mariconti, M.Vimercati, G.Corbucci, and G.Boriani.

Published
2008

4. Si puo’ migliorare la stratificazione del rischio tromboembolico combinando il CHADS2 score con presenza e durata della fibrillazione atriale?

Author

Botto, G., Padeletti, L., Santini, M., Capucci, A., Gulizia, M. M., Zolezzi, F., Favale, S., Molon, G., Ricci, R., Biffi, M., Mariconti, B., Vimercati, M., Corbucci, G., Boriani, Giuseppe, G.Botto, L.Padeletti, M.Santini, A.Capucci, MM. Gulizia, F.Zolezzi, S.Favale, G.Molon, R.Ricci, M.Biffi, B.Mariconti, M.Vimercati, G.Corbucci, and G.Boriani

Published
2008

5. May we rely on standard methods fora atrial fibrillation detection?

Author

BORIANI, GIUSEPPE, BIFFI, MAURO, L. Padeletti, M. Santini, A. Capucci, M. Gulizia, F. Zolezzi, S. Favale, G. Molon, R. Ricci, M. Luzi, M. Vimercati, G. Corbucci, G.L. Botto, G.Boriani, L.Padeletti, M.Santini, A.Capucci, M.Gulizia, F.Zolezzi, S.Favale, G.Molon, R.Ricci, M.Biffi, M.Luzi, M.Vimercati, G.Corbucci, and GL.Botto

Subjects
ATRIAL FIBRILLATION
Published
2008

10. Far-field R wave oversensing in dual-chamber pacemakers designed for atrial arrhythmia management: effect of pacing site and lead tip to ring distance

Author

Luigi Padeletti, Giuseppe Inama, Michele Massimo Gulizia, Massimo Santini, Giuseppe Boriani, Andrea Grammatico, Fabio Ferri, Alessandro Capucci, Rossana Raneri, Paolo Rizzon, Renato Pietro Ricci, Francesco Miraglia, Gianluca Botto, G.Inama, M.Santini, L.Padeletti, G.Boriani, G.Botto, A.Capucci, M.Gulizia, R.Riccci, P.Rizzon, F.Ferri, F.Miraglia, R.Raneri, and A.Grammatico

Subjects
Tachycardia, Male, Tachycardia, Ectopic Atrial, medicine.medical_specialty, Pacemaker, Artificial, Lower risk, QRS complex, Electrocardiography, Internal medicine, medicine, Humans, Prospective Studies, Lead (electronics), Prospective cohort study, Aged, Equipment Design, Equipment Failure, Female, medicine.diagnostic_test, business.industry, General Medicine, Surgery, Pacemaker, Ectopic Atrial, medicine.anatomical_structure, Artificial, Cardiology, Right atrium, Implant, medicine.symptom, Cardiology and Cardiovascular Medicine, business
Abstract

INAMA, G., et al.: Far-Field R Wave Oversensing in Dual Chamber Pacemakers Designed for Atrial Arrhythmia Management: Effect of Pacing Site and Lead Tip to Ring Distance. The aim of the study was to determine the incidence and practical implications of far-field R wave oversensing (FFRWO) and its association with pacing site and lead tip to ring spacing (TTRS) in implantable devices designed to diagnose and treat atrial tachyarrhythmias and programmed with a fixed and short postventricular blanking period. The study included 395 patients who were implanted with a DDDRP pacemaker and prospectively followed. At implant and follow-up visits FFRWO was assessed by analyzing lead electrical measures and atrial tachyarrhythmic episodes collected in the device diagnostics. During a median follow-up of 12 months 11 (2.8%) of 395 patients showed a clinically significant FFRWO that induced inappropriate detection or pacemaker malfunctioning. The atrial pacing site of these 11 patients was right atrium appendage (RAA) for 3 patients, representing 1.1% of 254 RAA patients, coronary sinus ostium (CSO) for 7 patients, representing 7.4% of 94 CSO patients (P0.005 vs RAA), and lateral wall (LW) for 1 (2.9%) of 34 LW patients. The minimal value of the FFRWO to P wave ratio, measured at implant, associated with a clinically significant FFRWO was 0.6; therefore, a value of 0.5 was used as a cutoff to identify patients at risk of undesirable device behavior induced by FFRWO: there were 11 (9.6%) of 114 of RAA patients with short (or = 10 mm) TTRS, 22 (18.8%) of 117 of RAA patients with long (or = 17 mm) TTRS (P0.05 vs short TTRS), 21 (30.6%) of 64 of CSO patients short TTRS (P0.001 vs RAA patients with short TTRS) and 3 (30%) of 10 of CSO patients with long TTRS. The analysis showed that, despite the short postventricular blanking time, FFRWO inducing undesired functioning in AT500 pacemakers is infrequent (2.8% of patients). Compared to RAA, the CSO lead position was more frequently associated with FFRWO.TTRS10 mm was associated with lower risk of clinically significant FFRWO in RAA. (PACE 2004; 27:1221-1230).

Published
2004

11. Definizione dei parametri predittivi di efficacia delle terapie di stimolazione antitadicardicaper l’interruzione delle tachiaritmie atriali in pazienti con malattia del nodo del seno impiantati con un pacemaker specifico: analisi uni e multivariata del registro italiano AT 500

Author

A. Spampinato, M. Santini, A. Capucci, G. Molon, M. Silvetti, M. Martelli, T. DeSanto, BORIANI, GIUSEPPE, A.Spampinato, M.Santini, A.Capucci, G.Boriani, G.Molon, M.Silvetti, M.Martelli, and T.DeSanto

Published
2004

13. Atrial tachyarrhythmia recurrence temporal patterns in bradycardia patients implanted with antitachycardia pacemakers

Author

Gianluca Botto, Alessandro Capucci, Massimo Santini, Michele Gulizia, Luigi Padeletti, Andrea Grammatico, Renato Ricci, Giuseppe Inama, Antonio Galati, Massimilano Pepe, Francesco Solimene, Giuseppe Boriani, R.Ricci, M.Santini, L.Padeletti, G.Boriani, A.Capucci, GL.Botto, M.Gulizia, G.Inama, A.Galati, F.Solimene, M.Pepe, and A.Grammatico

Subjects
Bradycardia, Adult, Male, Tachycardia, Ectopic Atrial, medicine.medical_specialty, Pacemaker, Artificial, Sinus bradycardia, Population, Disease-Free Survival, Physiology (medical), Internal medicine, Tachycardia, Atrial Fibrillation, medicine, 80 and over, Secondary Prevention, Humans, New device, education, Aged, Aged, 80 and over, education.field_of_study, Female, Incidence, Middle Aged, United States, Atrial pacing, business.industry, Atrial fibrillation, medicine.disease, Confidence interval, Pacemaker, Ectopic Atrial, Multicenter study, Artificial, Cardiology, medicine.symptom, Cardiology and Cardiovascular Medicine, business
Abstract

New-generation pacemakers allow continuous atrial tachyarrhythmia (AT) monitoring that provides accurate information about AT type, frequency, burden, and temporary evolution.We performed a prospective multicenter study to describe AT temporal patterns in patients with sinus bradycardia and AT. Two hundred forty patients (123 men; age 71 +/- 8 years) were implanted with a DDDRP pacemaker (model AT500, Medtronic Inc.). All patients were followed for 13 months. The first-month stabilization period of all patients was discarded from analysis. Seventy percent of patients had AT recurrences. Mean time to first AT recurrence (48.2 days, 95% confidence interval [CI] 37.0-59.5 days) was significantly longer than the time between first and second AT episode (10.3 days, 95% CI 6.7-13.9 days, P0.01). A minority of patients had a uniform time distribution of AT recurrences:25% of patients had AT episodes in more than 6 of the 12 months considered in the study. The probability density function of consecutive sinus rhythm days between AT episodes was calculated for each of 40 patients who experienced25 AT episodes and fitted by power law and exponential functions. The best fit was obtained by power law function in 60% of patients, by exponential function in 10%, and the two models gave comparable results in 30% of patients.In our population of patients with a history of sinus bradycardia and AT who were implanted with a new device equipped with atrial pacing therapies, 30% did not experience AT recurrences in the 12-month study period. Analysis of interevent time showed that in 60% of patients AT recurrences do not follow a uniform or random distribution. These findings bring into question the use of cross-over design and time to first AT recurrence as a clinical outcome in trials for AT therapy in this patient population.

Published
2004

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