1. Serum levels of tetracycline after different administration forms
- Author
-
A.E. Altmann, A.H.J. Gijzen, H. J. Buytendijk, Beeuwkes H, Maesen F, and Brombacher Pj
- Subjects
Chromatography ,Time Factors ,Chemistry ,Tetracycline ,Biochemistry (medical) ,Clinical Biochemistry ,Capsules ,General Medicine ,Coated tablets ,Biochemistry ,Resorption ,Dilution ,Agar plate ,Oral administration ,Spectrophotometry ,Delayed-Action Preparations ,medicine ,Humans ,Chelation ,Biological Assay ,Fluorometry ,medicine.drug ,Chelating Agents ,Tablets - Abstract
Serum levels of tetracycline after oral administration were studied by different methods. A generally used microbiological dilution method is of no value; there is agreement between an agar plate diffusion technique and a fluorimetric procedure. It seems that addition of chelating compounds has a good effect on intestinal resorption while the use of coated tablets gives less favourable results.
- Published
- 1968