553 results on '"ANALYSE MATHEMATIQUE"'
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2. Equilibrium Configurations of a Symmetric Body Immersed in a Stationary Navier–Stokes Flow in a Planar Channel
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Berchio, Elvise, Bonheure, Denis, Galdi, Giovanni Paolo, Gazzola, Filippo, Perotto, Simona, Berchio, Elvise, Bonheure, Denis, Galdi, Giovanni Paolo, Gazzola, Filippo, and Perotto, Simona
- Abstract
We study the equilibrium configurations for several fluid-structure interaction problems. The fluid is confined in a 2D unbounded channel that contains a body, free to move inside the channel with rigid motions (transversal translations and rotations). The motion of the fluid is generated by a Poiseuille inflow/outflow at infinity and governed by the stationary Navier-Stokes equations. For a model where the fluid is the air and the body represents the cross-section of a suspension bridge, therefore also subject to restoring elastic forces, we prove that for small inflows there exists a unique equilibrium position, while for large inflows we numerically show the appearance of additional equilibria. A similar uniqueness result is also obtained for a discretized 3D bridge, consisting in a finite number of cross-sections interacting with the adjacent ones. The very same model, but without restoring forces, is used to describe the mechanism of the Leonardo da Vinci ferry, which is able to cross a river without engines. We numerically determine the optimal orientation of the ferry that allows it to cross the river in minimal time., SCOPUS: ar.j, info:eu-repo/semantics/published
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- 2024
3. Real analysis
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Towsley, Gary W., author
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Mathematical analysis ,Functional analysis ,Analyse mathématique ,Analyse fonctionnelle - Abstract
This book is derived from lectures the author has given in the Real Analysis course at SUNY Geneseo over the last fourty-four years.
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- 2021
4. The Clausius-Mossotti formula
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Duerinckx, Mitia, Gloria, Antoine, Duerinckx, Mitia, and Gloria, Antoine
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info:eu-repo/semantics/published
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- 2023
5. Continuum percolation in stochastic homogenization and the effective viscosity problem
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Duerinckx, Mitia, Gloria, Antoine, Duerinckx, Mitia, and Gloria, Antoine
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info:eu-repo/semantics/published
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- 2023
6. Non-perturbative approach to the Bourgain-Spencer conjecture in stochastic homogenization
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Duerinckx, Mitia and Duerinckx, Mitia
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info:eu-repo/semantics/published
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- 2023
7. On Einstein's effective viscosity formula
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Duerinckx, Mitia, Gloria, Antoine, Duerinckx, Mitia, and Gloria, Antoine
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info:eu-repo/semantics/published
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- 2023
8. A Sharp Gradient Estimate and $$W^{2,q}$$ Regularity for the Prescribed Mean Curvature Equation in the Lorentz-Minkowski Space
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Bonheure, Denis, Iacopetti, Alessandro, Bonheure, Denis, and Iacopetti, Alessandro
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We consider the prescribed mean curvature equation for entire spacelike hypersurfaces in the Lorentz-Minkowski space, namely -div(∇u1, SCOPUS: ar.j, info:eu-repo/semantics/published
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- 2023
9. Long-time dynamics of a hinged-free plate driven by a nonconservative force
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Bonheure, Denis, Gazzola, Filippo, Lasiecka, Irena, Webster, Justin, Bonheure, Denis, Gazzola, Filippo, Lasiecka, Irena, and Webster, Justin
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info:eu-repo/semantics/inPress
- Published
- 2022
10. Sedimentation of random suspensions and the effect of hyperuniformity
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Duerinckx, Mitia, Gloria, Antoine, Duerinckx, Mitia, and Gloria, Antoine
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This work is concerned with the mathematical analysis of the bulk rheology of random suspensions of rigid particles settling under gravity in viscous fluids. Each particle generates a fluid flow that in turn acts on other particles and hinders their settling. In an equilibrium perspective, for a given ensemble of particle positions, we analyze both the associated mean settling speed and the velocity fluctuations of individual particles. In the 1970s, Batchelor gave a proper definition of the mean settling speed, a 60-year-old open problem in physics, based on the appropriate renormalization of long-range particle contributions. In the 1980s, a celebrated formal calculation by Caflisch and Luke suggested that velocity fluctuations in dimension d= 3 should diverge with the size of the sedimentation tank, contradicting both intuition and experimental observations. The role of long-range self-organization of suspended particles in form of hyperuniformity was later put forward to explain additional screening of this divergence in steady-state observations. In the present contribution, we develop the first rigorous theory that allows to justify all these formal calculations of the physics literature., SCOPUS: ar.j, info:eu-repo/semantics/published
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- 2022
11. Eigenvalue Fluctuations for Random Elliptic Operators in Homogenization Regime
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Duerinckx, Mitia and Duerinckx, Mitia
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This work is devoted to the asymptotic behavior of eigenvalues of an elliptic operator with rapidly oscillating random coefficients on a bounded domain with Dirichlet boundary conditions. A sharp convergence rate is obtained for eigenvalues towards those of the homogenized problem, as well as a quantitative two-scale expansion result for eigenfunctions. Next, a quantitative central limit theorem is established for fluctuations of isolated eigenvalues; more precisely, a pathwise characterization of eigenvalue fluctuations is obtained in terms of the so-called homogenization commutator, in parallel with the recent fluctuation theory for the solution operator., SCOPUS: ar.j, info:eu-repo/semantics/published
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- 2022
12. Ladder Operators and Hidden Algebras for Shape Invariant Nonseparable and Nondiagonalizable Models with Quadratic Complex Interaction. I. Two-Dimensional Model
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Marquette, Ian, Quesne, Christiane, Marquette, Ian, and Quesne, Christiane
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A shape invariant nonseparable and nondiagonalizable two-dimensional model with quadratic complex interaction, first studied by Cannata, Ioffe, and Nishnianidze, is re-examined with the purpose of exhibiting its hidden algebraic structure. The two operators A+ and A−, coming from the shape invariant supersymmetrical approach, where A+ acts as a raising operator while A− annihilates all wavefunctions, are completed by introducing a novel pair of operators B+ and B−, where B− acts as the missing lowering operator. These four operators then serve as building blocks for constructing gl(2) generators, acting within the set of associated functions belonging to the Jordan block corresponding to a given energy eigenvalue. This analysis is extended to the set of Jordan blocks by constructing two pairs of bosonic operators, finally yielding an sp(4) algebra, as well as an osp(1/4) superalgebra. Hence, the hidden algebraic structure of the model is very similar to that known for the two-dimensional real harmonic oscillator., SCOPUS: ar.j, info:eu-repo/semantics/published
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- 2022
13. Quantitative homogenization theory for random suspensions in steady Stokes flow
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Duerinckx, Mitia and Duerinckx, Mitia
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info:eu-repo/semantics/published
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- 2022
14. Effective viscosity of random suspensions without uniform separation
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Duerinckx, Mitia and Duerinckx, Mitia
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info:eu-repo/semantics/published
- Published
- 2022
15. Approximate Normal Forms via Floquet–Bloch Theory: Nehorošev Stability for Linear Waves in Quasiperiodic Media
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Christopher Shirley, Antoine Gloria, Mitia Duerinckx, Laboratoire de Mathématiques d'Orsay (LMO), Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Université libre de Bruxelles (ULB), Laboratoire Jacques-Louis Lions (LJLL (UMR_7598)), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), Département de Mathématique [Bruxelles] (ULB), Faculté des Sciences [Bruxelles] (ULB), and Université libre de Bruxelles (ULB)-Université libre de Bruxelles (ULB)
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Floquet theory ,FOS: Physical sciences ,Lambda ,01 natural sciences ,Stability (probability) ,Mathematics - Spectral Theory ,Mathematics - Analysis of PDEs ,[MATH.MATH-MP]Mathematics [math]/Mathematical Physics [math-ph] ,0103 physical sciences ,FOS: Mathematics ,[MATH.MATH-AP]Mathematics [math]/Analysis of PDEs [math.AP] ,Ergodic theory ,[MATH]Mathematics [math] ,0101 mathematics ,Nonlinear Sciences::Pattern Formation and Solitons ,Spectral Theory (math.SP) ,Mathematical Physics ,Physique théorique et mathématique ,Mathematical physics ,Physics ,Operator (physics) ,010102 general mathematics ,Statistical and Nonlinear Physics ,Mathematical Physics (math-ph) ,16. Peace & justice ,Exponential function ,Mathématiques ,Flow (mathematics) ,Quasiperiodic function ,010307 mathematical physics ,Analyse mathématique ,Analysis of PDEs (math.AP) ,[MATH.MATH-SP]Mathematics [math]/Spectral Theory [math.SP] - Abstract
We study the long-time behavior of the Schrodinger flow in a heterogeneous potential $$\lambda V$$ with small intensity $$00$$ . More precisely, the approximate normal form leads to an accurate long-time description of the Schrodinger flow as an effective unitary correction of the free flow. The approach is robust and generically applies to linear waves. For classical waves, for instance, this allows to extend diffractive geometric optics to quasiperiodically perturbed media.
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- 2021
- Full Text
- View/download PDF
16. Corrector Equations in Fluid Mechanics: Effective Viscosity of Colloidal Suspensions
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Antoine Gloria, Mitia Duerinckx, Département de Mathématique [Bruxelles] (ULB), Faculté des Sciences [Bruxelles] (ULB), Université libre de Bruxelles (ULB)-Université libre de Bruxelles (ULB), AP-HP. Université Paris Saclay, Laboratoire Jacques-Louis Lions (LJLL (UMR_7598)), and Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)
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Mécanique des fluides ,Complex system ,01 natural sciences ,Homogenization (chemistry) ,Point process ,Physics::Fluid Dynamics ,Colloid ,symbols.namesake ,Mathematics - Analysis of PDEs ,Mathematics (miscellaneous) ,[MATH.MATH-MP]Mathematics [math]/Mathematical Physics [math-ph] ,FOS: Mathematics ,[MATH.MATH-AP]Mathematics [math]/Analysis of PDEs [math.AP] ,Ergodic theory ,0101 mathematics ,Einstein ,ComputingMilieux_MISCELLANEOUS ,Physics ,Mechanical Engineering ,Probability (math.PR) ,010102 general mathematics ,Fluid mechanics ,Stokes flow ,[MATH.MATH-PR]Mathematics [math]/Probability [math.PR] ,010101 applied mathematics ,Mathématiques ,Classical mechanics ,symbols ,Analyse mathématique ,Mathematics - Probability ,Analysis ,Analysis of PDEs (math.AP) - Abstract
Consider a colloidal suspension of rigid particles in a steady Stokes flow. In a celebrated work, Einstein argued that in the regime of dilute particles the system behaves at leading order like a Stokes fluid with some explicit effective viscosity. In the present contribution, we rigorously define a notion of effective viscosity, regardless of the dilute regime assumption. More precisely, we establish a homogenization result for when particles are distributed according to a given stationary and ergodic random point process. The main novelty is the introduction and analysis of suitable corrector equations., SCOPUS: ar.j, info:eu-repo/semantics/published
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- 2020
- Full Text
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17. Robustness of the pathwise structure of fluctuations in stochastic homogenization
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Felix Otto, Mitia Duerinckx, Antoine Gloria, Département de Mathématique [Bruxelles] (ULB), Faculté des Sciences [Bruxelles] (ULB), Université libre de Bruxelles (ULB)-Université libre de Bruxelles (ULB), Laboratoire Jacques-Louis Lions (LJLL (UMR_7598)), Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Max Planck Institute for Mathematics in the Sciences (MPI-MiS), Max-Planck-Gesellschaft, Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), and Université Libre de Bruxelles [Bruxelles] (ULB)
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Statistics and Probability ,Covariance function ,01 natural sciences ,Homogenization (chemistry) ,010104 statistics & probability ,Mathematics - Analysis of PDEs ,FOS: Mathematics ,[MATH.MATH-AP]Mathematics [math]/Analysis of PDEs [math.AP] ,Statistical physics ,Statistique mathématique ,0101 mathematics ,Algebraic number ,Scaling ,Mathematics ,Continuum (measurement) ,Mathematical finance ,Probability (math.PR) ,010102 general mathematics ,Conductance ,Méthodes mathématiques et quantitatives ,Probabilités ,[MATH.MATH-PR]Mathematics [math]/Probability [math.PR] ,Statistics, Probability and Uncertainty ,Analyse mathématique ,Mathematics - Probability ,Analysis ,Analysis of PDEs (math.AP) - Abstract
We consider a linear elliptic system in divergence form with random coefficients and study the random fluctuations of large-scale averages of the field and the flux of the solution operator. In the context of the random conductance model, we developed in a previous work a theory of fluctuations based on the notion of homogenization commutator: we proved that the two-scale expansion of this special quantity is accurate at leading order in the fluctuation scaling when averaged on large scales (as opposed to the two-scale expansion of the solution operator taken separately) and that the large-scale fluctuations of the field and the flux of the solution operator can be recovered from those of the commutator. This implies that the large-scale fluctuations of the commutator of the corrector drive all other large-scale fluctuations to leading order, which we refer to as the pathwise structure of fluctuations in stochastic homogenization. In the present contribution we extend this result in two directions: we treat continuum elliptic (possibly non-symmetric) systems and allow for strongly correlated coefficient fields (Gaussian-like with a covariance function that can display an arbitrarily slow algebraic decay at infinity). Our main result shows in this general setting that the two-scale expansion of the homogenization commutator is still accurate to leading order when averaged on large scales, which illustrates the robustness of the pathwise structure of fluctuations., SCOPUS: ar.j, info:eu-repo/semantics/published
- Published
- 2020
- Full Text
- View/download PDF
18. A new spectral analysis of stationary random Schrödinger operators
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Duerinckx, Mitia, Shirley, Christopher, Duerinckx, Mitia, and Shirley, Christopher
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Motivated by the long-time transport properties of quantum waves in weakly disordered media, the present work puts random Schrödinger operators into a new spectral perspective. Based on a stationary random version of a Floquet type fibration, we reduce the description of the quantum dynamics to a fibered family of abstract spectral perturbation problems on the underlying probability space. We state a natural resonance conjecture for these fibered operators: in contrast with periodic and quasiperiodic settings, this would entail that Bloch waves do not exist as extended states but rather as resonant modes, and this would justify the expected exponential decay of time correlations. Although this resonance conjecture remains open, we develop new tools for spectral analysis on the probability space, and in particular, we show how ideas from Malliavin calculus lead to rigorous Mourre type results: we obtain an approximate dynamical resonance result and the first spectral proof of the decay of time correlations on the kinetic timescale. This spectral approach suggests a whole new way of circumventing perturbative expansions and renormalization techniques., SCOPUS: ar.j, info:eu-repo/semantics/published
- Published
- 2021
19. On nonlinear schrödinger equations with random initial data
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Duerinckx, Mitia and Duerinckx, Mitia
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This note is concerned with the global well-posedness of nonlinear Schrödinger equations in the continuum with spatially homogeneous random initial data., SCOPUS: ar.j, info:eu-repo/semantics/published
- Published
- 2021
20. A Paneitz–Branson type equation with Neumann boundary conditions
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Bonheure, Denis, Cheikh-Ali, Hussein, Alves Do Nascimento Filho, Robson, Bonheure, Denis, Cheikh-Ali, Hussein, and Alves Do Nascimento Filho, Robson
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We consider the best constant in a critical Sobolev inequality of second order.We show non-rigidity for the optimizers above a certain threshold, namely, we prove that the best constant is achieved by a nonconstant solution of the associated fourth order elliptic problem under Neumann boundary conditions.Our arguments rely on asymptotic estimates of the Rayleigh quotient.We also show rigidity below another threshold., SCOPUS: ar.j, info:eu-repo/semantics/published
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- 2021
21. Unbounded mass radial solutions for the Keller–Segel equation in the disk
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Bonheure, Denis, Casteras, Jean-Baptiste, Román, Carlos, Bonheure, Denis, Casteras, Jean-Baptiste, and Román, Carlos
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info:eu-repo/semantics/published
- Published
- 2021
22. Bifurcation analysis of the Hardy-Sobolev equation
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Bonheure, Denis, Casteras, Jean-Baptiste, Gladiali, Francesca, Bonheure, Denis, Casteras, Jean-Baptiste, and Gladiali, Francesca
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In this paper, we prove existence of multiple non-radial solutions to the Hardy-Sobolev equation [Formula presented] where N≥3, s∈[0,2), [Formula presented] and [Formula presented]. We extend results of E.N. Dancer, F. Gladiali, M. Grossi (2017) [12] where only the case s=0 is considered. The results specially rely on a careful analysis of the kernel of the linearized operator. Moreover, thanks to monotonicity properties of the solutions, we separate two branches of non-radial solutions., SCOPUS: ar.j, info:eu-repo/semantics/published
- Published
- 2021
23. Lenard-Balescu correction to mean-field theory
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Duerinckx, Mitia, Saint-Raymond, Laure, Duerinckx, Mitia, and Saint-Raymond, Laure
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info:eu-repo/semantics/published
- Published
- 2021
24. On the size of chaos via Glauber calculus in the classical mean-field dynamics
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Duerinckx, Mitia and Duerinckx, Mitia
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info:eu-repo/semantics/inPress
- Published
- 2021
25. Approximate normal forms via Floquet-Bloch theory: Nehorosev stability for linear waves in quasiperiodic media
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Duerinckx, Mitia, Gloria, Antoine, Shirley, Christopher, Duerinckx, Mitia, Gloria, Antoine, and Shirley, Christopher
- Abstract
info:eu-repo/semantics/inPress
- Published
- 2021
26. Hardy-Sobolev inequalities with singularities on non smooth boundary. Part 2: Influence of the global geometry in small dimensions
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Cheikh-Ali, Hussein and Cheikh-Ali, Hussein
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We consider Hardy-Sobolev nonlinear equations on domains with singularities. We introduced this problem in Cheikh-Ali [4]. Under a local geometric hypothesis, namely that the generalized mean curvature is negative (see (7) below), we proved the existence of extremals for the relevant Hardy-Sobolev inequality for large dimensions. In the present paper, we tackle the question of small dimensions that was left open. We introduce a “mass”, that is a global quantity, the positivity of which ensures the existence of extremals in small dimensions. As a byproduct, we prove the existence of solutions to a perturbation of the initial equation via the Mountain-Pass Lemma., SCOPUS: ar.j, info:eu-repo/semantics/inPress
- Published
- 2021
27. De l'influence des conditions aux bords périodiques pour la simulation de quelques quantités d'intérêt pour la chimie séparative
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Guerny, Anne-Françoise de, Laboratoire Jacques-Louis Lions (LJLL (UMR_7598)), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Sorbonne Université, Yvon Maday, and Jean-François Dufrêche
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Equation de Stokes ,Conditions aux bords périodiques ,Molecular dynamics ,[INFO.INFO-NA]Computer Science [cs]/Numerical Analysis [cs.NA] ,Stokes equation ,Mathematical analysis ,Periodic boundariy conditions ,Potentiel de McMillan et Mayer ,Dynamique moléculaire ,[MATH.MATH-AP]Mathematics [math]/Analysis of PDEs [math.AP] ,McMillan and Mayer potential ,Solvation phenomenon ,Analyse mathématique ,Phénomène de solvatation - Abstract
The objective of this thesis is to study the influence of periodic conditions and in particular the corrections to be made, depending on the period considered, in the calculation of certain quantities of interest from molecular dynamics simulations. The latter are particularly useful for the understanding of solvation phenomena of molecules in solution and are naturally useful for the study of radioactive waste management. We are particularly interested in the study of the potential of Mean Force, described in the McMillan and Mayer formalism between two charged solutes in solution. We start by calculating analytically the potential of such a system by considering periodic edge conditions of period L. The calculation is based on the forces acting on one of the particles and on the clever joining of the terms of the obtained sum. We can finally verify that, at large distances, the potential converges to a coulombic potential, and we obtain a corrective term in L-5. From simulations using the Umbrella Sampling method combined with the WHAM method, we correct the McMillan and Mayer potential of sodium chloride, and lanthanides, from the term obtained in order to observe the resulting association constant. Moreover, we study the diffusion coefficient of a particle in a confined medium. Our calculation is based on the passage of the Stokes equation in Fourier, which gives us ODEs with distributions that we solve to obtain the velocity of the particle. Then, limited developments lead to the diffusion coefficient including a corrective term in L-1.; L'objectif de cette thèse est d'étudier l'influence des conditions périodiques et notamment les corrections à apporter, en fonction de la période considérée, dans le calcul de certaines quantités d'intérêt tirées de simulations de dynamique moléculaire. Ces dernières sont particulièrement profitables pour la compréhension des phénomènes de solvatation de molécules en solution et voient naturellement leur utilité pour l'étude de la gestion des déchets radioactifs. Nous nous intéressons notamment à l'étude du potentiel de Force moyenne, décrit dans le formalisme de McMillan et Mayer entre deux solutés chargés en solution. On commence par calculer analytiquement le potentiel d'un tel système en considérant des conditions aux bords périodiques de période L. Le calcul se base sur les forces agissant sur l'une des particules et sur la réunion astucieuse des termes de la somme obtenue. On peut finalement vérifier que, à grande distance, le potentiel converge vers un potentiel coulombien, et on obtient un terme correctif en L-5. A partir de simulations à partir de la méthode du Umbrella Sampling combinée à la méthode WHAM, on corrige le potentiel de McMillan et Mayer de chlorure de sodium, et de lanthanides, à partir du terme obtenu afin d'observer la constante d'association qui en résulte. Par ailleurs, on étudie le coefficient de diffusion d'une particule en milieu confiné. Notre calcul repose sur le passage de l'équation de Stokes en Fourier, ce qui nous donne des EDO avec distributions que l'on résout pour obtenir la vitesse de la particule. Ensuite, des développements limités aboutissent au coefficient de diffusion comprenant un terme correctif en L-1.
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- 2021
28. Hardy-Sobolev inequalities with singularities on non smooth boundary. Part 2: Influence of the global geometry in small dimensions
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Hussein Cheikh Ali, Département de mathématiques Université Libre de Bruxelles, Université libre de Bruxelles (ULB), Institut Élie Cartan de Lorraine (IECL), and Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS)
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Pure mathematics ,Applied Mathematics ,010102 general mathematics ,Perturbation (astronomy) ,Curvature ,Non smooth ,01 natural sciences ,Sobolev inequality ,010101 applied mathematics ,Nonlinear system ,Mathématiques ,[MATH.MATH-AP]Mathematics [math]/Analysis of PDEs [math.AP] ,Gravitational singularity ,Generalized mean ,0101 mathematics ,Analyse mathématique ,Analysis ,Mathematics - Abstract
We consider Hardy-Sobolev nonlinear equations on domains with singularities. We introduced this problem in Cheikh-Ali [4]. Under a local geometric hypothesis, namely that the generalized mean curvature is negative (see (7) below), we proved the existence of extremals for the relevant Hardy-Sobolev inequality for large dimensions. In the present paper, we tackle the question of small dimensions that was left open. We introduce a “mass”, that is a global quantity, the positivity of which ensures the existence of extremals in small dimensions. As a byproduct, we prove the existence of solutions to a perturbation of the initial equation via the Mountain-Pass Lemma., info:eu-repo/semantics/inPress
- Published
- 2021
- Full Text
- View/download PDF
29. Propagation of chaos and corrections to mean-field for interacting particles
- Author
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Duerinckx, Mitia
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Mathématiques ,Equations différentielles et aux dérivées partielles ,Probabilités ,Analyse mathématique ,Physique théorique et mathématique - Abstract
info:eu-repo/semantics/published
- Published
- 2020
30. Stimulation cérébrale multi-sites : modèles dynamiques et applications aux crises d'épilepsie
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Arrais, Marouan, Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Rennes 1, Fabrice Wendling, Julien Modolo, STAR, ABES, Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), and Université de Rennes
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Signal processing ,Epilepsy ,[INFO.INFO-TS] Computer Science [cs]/Signal and Image Processing ,Modeling ,Stimulation cérébrale ,Epilepsie ,Mathematical analysis ,Traitement du signal ,Ingénierie biomédicale ,[INFO.INFO-TS]Computer Science [cs]/Signal and Image Processing ,Brain stimulation ,Modélisation ,Biomedical engineering ,Analyse mathématique - Abstract
More than 17 million epileptic patients worldwide are not effectively relieved by medication. For these patients, electrical stimulation of the brain is a promising technique for stopping recurrent seizures that disrupt their daily lives. However, the effects of electrical stimulation on brain activity are not yet well understood. In addition, the stimulation parameters are often chosen empirically, based on trial-and-error approach, which limits the effectiveness of this therapy. In this thesis, we aim, using bio-inspired computational models and mathematical methods derived from the theory of dynamical systems, to design an optimal stimulation capable of attenuating or even suppressing epileptic brain activity., Près de 17 millions de patients épileptiques dans le monde ne sont pas soulagés efficacement par les médicaments. Pour ces patients, la stimulation électrique du cerveau est une technique pour arrêter les crises récurrentes qui perturbent leur vie quotidienne. Cependant, les effets de la stimulation électrique sur l'activité du cerveau ne sont pas encore bien compris. En outre, les paramètres de stimulation sont souvent choisis de manière empirique, ce qui limite l'efficacité de cette thérapie. Au cours de cette thèse, nous visons, en utilisant des modèles computationnels bio-inspirés et des méthodes mathématiques dérivées de la théorie des systèmes dynamiques, à concevoir des méthodes de stimulation optimales capables d'atténuer voire de supprimer l'activité cérébrale épileptique.
- Published
- 2020
31. Mathematical modelling, analysis and simulations to improve the control of Miridae, a cocoa pest
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Djoukwe Tapi, Myriam, Botanique et Modélisation de l'Architecture des Plantes et des Végétations (UMR AMAP), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université de Douala, Samuel Bowong, Yves Dumont (yves.dumont@cirad.fr), and EPITAG
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Delay differential equations ,Systèmes monotones ,Sahlbergella singularis ,Numerical simulation ,"Systèmes réguliers par morceaux" ,[SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics, Phylogenetics and taxonomy ,Stabilité ,Ravageurs du cacaoyer ,Lutte contre les ravageurs ,Pest control ,[SDV.EE.ECO]Life Sciences [q-bio]/Ecology, environment/Ecosystems ,Equations différentielles à retard ,Confusion sexuelle ,[MATH]Mathematics [math] ,Piecewise smooth system ,Mathematical models ,Stability analysis ,Mating disruption ,[SDV.BV.BOT]Life Sciences [q-bio]/Vegetal Biology/Botanics ,Cooperative system ,Cocoa pest ,Chemical control ,[SDE.BE]Environmental Sciences/Biodiversity and Ecology ,Modèles mathématiques ,Analyse mathématique ,Simulations numériques - Abstract
Cocoa is an important cash crop in Central and West Africa, especially in Cameroon. In this part of the world, cacao production is impacted by several diseases, like the Cocoa Swollen Shoot Virus (CSSV) and the black pod disease, and several pests, like Miridae, Distantiella theobroma and Sahlbergella singularis, causing significant damage to pods and vegetative parts of the cocoa tree, and thus impacting the cocoa production. However, the damage and losses associated with this pest remain difficult to estimate due in particular to the bio/ecology of this species (camouflage, low Statistical models have shown to be ineffective in describing these dynamics. That is why we havedeveloped several Mathematical models to describe the time evolution dynamics of mirids, including the effect of different control methods. After an introductory chapter where we recall the biology and ecology of mirids, we develop, analyze and study a compartmental cooperative periodic and nonperiodic model in chapter 2. Then, considering time developments and sexual maturation duration for females, we develop and study a delayed cooperative model (with and without periodic parameters). In this latter model, we consider different control methods, including chemical control (insecticides) and semi-chemical control (sexual confusion and trapping). Through our numerical simulations, we recover recommendation given by mirid control organizations for the use of insecticides and show that chemical treatment can be replaced efficiently by mating disrupting and trapping. We also derive a global sensitivity analysis highlighting the importance of some key parameters. Then, based on the previous results, we develop, in chapter 3, a more complex delay model, modeling mating disrupting and trapping, using the piecewise-smooth system approach. Our analysis shows the existence of two thresholds based on mirid’s biological parameters: one under which the control has no effect on established populations, and the second above which control on established populations is feasible. We illustrate our results with various numerical simulations and discuss the results. We conclude our thesis with possible extension of our models and also applications in the field.; Le cacao est la principale culture de rente Afrique Centrale Occidentale, en particulier au Cameroun. Dans cette région du monde, la production est affectée par plusieurs maladies parmi lesquelles, le Cacao Swollen Shoot Virus (CSSV) et la pourriture brune du cacaoyer causée par Phytophthora sp.. Elle est aussi affectée par les ravageurs notamment les mirides Distantiella theobroma et Sahlbergella singularis qui causent d’énormes dégâts sur les cabosses et les parties végétatives du cacaoyer. Au Cameroun, S. singularis est décrite comme l’espèce la plus présente dans les cacaoyères et la plus préjudiciable pour la production. Cependant, les dégâts et les pertes associés à ce ravageur restent difficiles à estimer en raison de la bio-écologie de cette espèce (camouflage, faible nombre d’individus) empêchant une bonne estimation in situ de la dynamique des populations. Les modèles statistiques ont jusqu’alors été peu efficaces pour appréhender cette dynamique. Des modèles mathématiques semblent plus adaptées. C’est pourquoi, dans le cadre de nos travaux, nous avons développé plusieurs modèles mathématiques pour décrire la dynamique d’évolution des mirides, mais aussi l’effet des différentes méthodes de contrôle sur les tailles de population de mirides. Après un chapitre introductif où nous rappelons la biologie et l’écologie des mirides, nous développons et analysons un modèle coopératif (en distinguant les cas où les paramètres sont périodiques ou pas) au chapitre 2 et nous obtenons les conditions sur la persistance ou non de la population des mirides. Ensuite, en tenant compte de la durée de développement larvaire et de la période de maturation des femelles, nous développons et étudions un modèle coopératif à retard (avec et sans paramètres périodiques). A ce modèle, nous appliquons les différentes méthodes de lutte: la lutte chimique (insecticides) et la lutte semiochimique (confusions sexuelle et piégeage). A l’aide de nos simulations numériques, nous obtenons des résultats en termes de recommandations pour lutte contre les mirides et montrons que le traitement chimique peut être remplacé efficacement par le traitement semiochimique. Nous faisons une analyse de sensibilité globale du modèle mettant en exergue l’importance de certains paramètres clés. Sur la base des résultats précédents, nous développons au chapitre 3, un modèle à retard plus complexe, modélisant la confusion sexuelle et le piégeage, en utilisant l’approche des systèmes réguliers par morceaux. Notre analyse mathématique montre l’existence de deux seuils basés sur les paramètres biologiques des mirides: un seuil sous lequel le contrôle n’a aucun effet sur les populations établies, et le second seuil qui permet de contrôler les populations établies. Nous illustrons nos résultats par des simulations numériques. Nous concluons notre thèse avec une extension possible de nos modèles, mais également nous proposons des travaux qui peuvent être menés sur le terrain.
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- 2020
32. Higher-order pathwise theory of fluctuations in stochastic homogenization
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Mitia Duerinckx, Felix Otto, Département de Mathématique [Bruxelles] (ULB), Faculté des Sciences [Bruxelles] (ULB), Université libre de Bruxelles (ULB)-Université libre de Bruxelles (ULB), Max Planck Institute for Mathematics in the Sciences (MPI-MiS), Max-Planck-Gesellschaft, and Duerinckx, Mitia
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Statistics and Probability ,[MATH.MATH-PR] Mathematics [math]/Probability [math.PR] ,Higher-order homogenization ,Gaussian ,Malliavin calculus ,01 natural sciences ,Homogenization (chemistry) ,law.invention ,010104 statistics & probability ,symbols.namesake ,Mathematics - Analysis of PDEs ,law ,FOS: Mathematics ,Fluctuations ,[MATH.MATH-AP]Mathematics [math]/Analysis of PDEs [math.AP] ,Statistical physics ,[MATH.MATH-AP] Mathematics [math]/Analysis of PDEs [math.AP] ,0101 mathematics ,ComputingMilieux_MISCELLANEOUS ,Physics ,Partial differential equation ,Homogenization commutator ,Applied Mathematics ,Numerical analysis ,Probability (math.PR) ,010102 general mathematics ,Stochastic homogenization ,Commutator (electric) ,Observable ,Probabilités ,[MATH.MATH-PR]Mathematics [math]/Probability [math.PR] ,Elliptic operator ,Equations différentielles et aux dérivées partielles ,Modeling and Simulation ,symbols ,Analyse mathématique ,Linear elliptic equation ,Mathematics - Probability ,Analysis of PDEs (math.AP) - Abstract
We consider linear elliptic equations in divergence form with stationary random coefficients of integrable correlations. We characterize the fluctuations of a macroscopic observable of a solution to relative order d2, where d is the spatial dimension; the fluctuations turn out to be Gaussian. As for previous work on the leading order, this higher-order characterization relies on a pathwise proximity of the macroscopic fluctuations of a general solution to those of the (higher-order) correctors, via a (higher-order) two-scale expansion injected into the “homogenization commutator”, thus confirming the scope of this notion. This higher-order generalization sheds a clearer light on the algebraic structure of the higher-order versions of correctors, flux correctors, two-scale expansions, and homogenization commutators. It reveals that in the same way as this algebra provides a higher-order theory for microscopic spatial oscillations, it also provides a higher-order theory for macroscopic random fluctuations, although both phenomena are not directly related. We focus on the model framework of an underlying Gaussian ensemble, which allows for an efficient use of (second-order) Malliavin calculus for stochastic estimates. On the technical side, we introduce annealed Calderón–Zygmund estimates for the elliptic operator with random coefficients, which conveniently upgrade the known quenched large-scale estimates., SCOPUS: ar.j, info:eu-repo/semantics/published
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- 2020
33. Periodic Solutions and Torsional Instability in a Nonlinear Nonlocal Plate Equation
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Ederson Moreira dos Santos, Filippo Gazzola, and Denis Bonheure
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nonlinear nonlocal plate equation ,periodic solutions ,Deformation (meteorology) ,01 natural sciences ,Instability ,35G31, 35Q74, 35B35, 35B40, 35B10, 74B20, 37C75 ,Physics::Fluid Dynamics ,Mathematics - Analysis of PDEs ,FOS: Mathematics ,0101 mathematics ,Plate equation ,Mathematics ,Applied Mathematics ,Mathematical analysis ,torsional stability ,010101 applied mathematics ,Mathématiques ,Computational Mathematics ,Nonlinear system ,Equations différentielles et aux dérivées partielles ,Evolution equation ,SISTEMAS DINÂMICOS ,Analyse mathématique ,Analysis ,Analysis of PDEs (math.AP) - Abstract
A thin and narrow rectangular plate having the two short edges hinged and the two long edges free is considered. A nonlinear nonlocal evolution equation describing the deformation of the plate is introduced: well-posedness and existence of periodic solutions are proved. The natural phase space is a particular second order Sobolev space that can be orthogonally split into two subspaces containing, respectively, the longitudinal and the torsional movements of the plate. Sufficient conditions for the stability of periodic solutions and of solutions having only a longitudinal component are given. A stability analysis of the so-called prevailing mode is also performed. Some numerical experiments show that instabilities may occur. This plate can be seen as a simplified and qualitative model for the deck of a suspension bridge, which does not take into account the complex interactions between all the components of a real bridge., 34 pages, 4 figures. The result of Theorem 6 is correct, but the proof was not correct. We slightly changed the proof in this updated version
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- 2019
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34. Defining the molecular and cellular mechanisms underlying wound repair and postnatal growth in the mouse epidermis
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Dekoninck, Sophie, Blanpain, Cédric, Brion, Jean Pierre, Richert, Bertrand, Parmentier, Marc, Franchimont, Denis, Jensen, Kim Bak, and Itzkovitz, Shalev S.I.
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Imbalance ,Postnatal growth ,Stem cell ,Croissance et développement [animal] ,Mathematical Modelling ,Leading edge ,Biologie moléculaire ,Wound healing ,Biologie cellulaire ,Epidermis ,Analyse mathématique ,Sciences biomédicales ,Progenitor - Abstract
The epidermis is the first barrier of protection of living organisms against external attacks. It is constantly renewed throughout life, through a process called "homeostasis", which ensures that every cell lost on its surface is replaced by new ones. Recent studies have shown that this balance is ensured by a hierarchy of stem cells (SC) and progenitors that perform 3 types of cell divisions, each having a fixed probability. Although the epidermis has been extensively studied during homeostasis, little is known about the cellular dynamics taking place when the epidermis must expand its surface. Are these probabilities of division immutable or can they change? In this project, we focused on two conditions of epidermal expansion: postnatal growth and wound healing. Using the mouse tail epidermis as a model, we show that the re-epithelialization after a wound is achieved via the formation of two transient compartments that are spatially and molecularly distinct :a leading edge and a proliferative hub. We show that the leading edge cells have a specific transcriptional signature that is independent of their quiescent state and we propose new markers not previously described. Using the technique of "lineage tracing", coupled with clonal analysis and mathematical modeling, we highlight the proliferation dynamics of SCs and progenitors during healing. We show that different populations of cells residing in different compartments, the hair follicle infundibulum and the interfollicular epidermis, acquire a similar dynamics and re-activate their SC while the progenitors increase their rate of proliferation without changing their division probabilities. This similar proliferation dynamics in two compartments of the epidermis suggests that division probabilities are not dictated by the cell of origin. Interestingly, cell dynamics is different during postnatal growth. Using lineage tracing, clonal analysis and single-cell transcriptional analysis, we demonstrate that the post-natal epidermis is composed of a homogeneous population of equipotent progenitors which ensure a harmonious tissue growth through a constant imbalance towards self-renewing divisions and an ever decreasing proliferation rate. On the other hand, we show that basal cells in the adult epidermis display a greater molecular heterogeneity and that this heterogeneity is acquired progressively at the end of growth. Finally, by coupling in vivo measurements and in vitro micro-patterning experiments, we show that the orientation of cell division of equipotent progenitors is locally influenced by the alignment of the collagen fibers of the underlying dermis. These data suggest that SC specification occurs late in postnatal development and that proliferation dynamics are not immutable and could therefore be influenced by extrinsic factors., L’épiderme est la première barrière de protection des organismes vivants contre des attaques extérieures. Il est constamment renouvelé au cours de la vie, via un processus appelé « homeostasie », qui assure que chaque cellule perdue à sa surface soit remplacée par de nouvelles. Des études récentes ont montré que cet équilibre était assuré par une hiérarchie de cellules souches (CS) et de progéniteurs qui réalisent 3 types de divisions cellulaires, chaque type de division ayant une probabilité fixe. Bien que l’épiderme ait été intensivement étudié durant l’homeostasie, peu de choses sont connues concernant la dynamique cellulaire prenant place lors de phénomènes où l’épiderme doit grandir. Ces probabilités de division sont-elles immuables ou peuvent-elles au contraire changer ?Dans ce projet, nous nous sommes intéressés à deux conditions d’expansion de l’épiderme :la croissance post-natale et la cicatrisation des plaies. En utilisant l’épiderme de la queue de souris comme modèle, nous montrons que la ré-épithélialisation d’une plaie est réalisée via la formation de deux compartiments cellulaires transitoires distincts spatialement et du point de vue moléculaire :un front de migration et un centre prolifératif. Nous montrons que les cellules du front de migration ont une signature transcriptionnelle spécifique qui est indépendante de leur état de quiescence et proposons de nouveaux marqueurs non décrits auparavant. En utilisant la technique du « lineage tracing », couplée à une analyse clonale et à de la modélisation mathématique, nous mettons en évidence la dynamique de prolifération des CS et des progéniteurs lors de la cicatrisation. Nous montrons que différentes populations de cellules résidant dans des compartiments différents, l’infundibulum du follicule pileux et l’épiderme interfolliculaire, acquièrent une dynamique similaire et ré-activent leur CS tandis que les progéniteurs augmentent leur taux de prolifération sans changer leur probabilité de division. Cette dynamique de prolifération similaire dans deux compartiments de l’épiderme suggère que les probabilités de divisions ne sont pas dictées par la cellule d’origine. De façon intéressante, la dynamique cellulaire est par contre différente durant la croissance post-natale. En utilisant le lineage tracing, l’analyse clonale et des analyses transcriptionnelles sur cellule unique, nous démontrons que l’épiderme post-natal est composé d’une population homogène de progéniteurs équipotents qui présentent un constant déséquilibre envers des divisions d’auto-renouvèlement et un taux de prolifération décroissant, assurant une croissance harmonieuse de l’épiderme. En revanche, les cellules basales de l’épiderme adulte montrent une plus grande hétérogénéité moléculaire et cet hétérogénéité est acquise progressivement à la fin de la croissance. Enfin, en couplant des mesures in vivo et des expériences de micro-patterning in vitro, nous montrons que l’orientation de la division cellulaire des progéniteurs équipotents est localement influencée par l’alignement des fibres de collagène du derme sous-jacent. Ces données suggèrent que la spécification des CS survient tardivement au cours du développement post-natal et que la dynamique de prolifération n’est pas immuable et pourraient donc être influencée par des facteurs extrinsèques., Doctorat en Sciences biomédicales et pharmaceutiques (Pharmacie), info:eu-repo/semantics/nonPublished
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- 2020
35. Relations between socio-economic factors and nutritional diet in Vietnam from 2004 to 2014: New insights using compositional data analysis
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Huong Thi Trinh, Joanna Morais, Michel Simioni, Christine Thomas-Agnan, Toulouse School of Economics (TSE), Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-École des hautes études en sciences sociales (EHESS)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Thuongmai University, Partenaires INRAE, Etudes de marché et sondages, Marchés, Organisations, Institutions et Stratégies d'Acteurs (UMR MOISA), Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Centre International de Hautes Etudes Agronomiques Méditerranéennes - Institut Agronomique Méditerranéen de Montpellier (CIHEAM-IAMM), and Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut National de la Recherche Agronomique (INRA)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)
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Data Analysis ,Statistics and Probability ,Epidemiology ,analyse mathématique ,Nutritional Status ,Context (language use) ,Diet Surveys ,modèle de régression ,01 natural sciences ,qualité nutritionnelle ,010104 statistics & probability ,03 medical and health sciences ,0302 clinical medicine ,diet pattern ,Health Information Management ,[MATH.MATH-ST]Mathematics [math]/Statistics [math.ST] ,Urbanization ,méthode statistique ,Economics ,Nutrition transition ,Humans ,compositional regression models ,Statistiques (Mathématiques) ,030212 general & internal medicine ,0101 mathematics ,équilibre alimentaire ,Socioeconomic status ,Probability ,modélisation ,2. Zero hunger ,Consumption (economics) ,Public economics ,Probabilités ,choix alimentaire ,vietnam ,macronutrient shares ,macronutriment ,Calorie intake ,[MATH.MATH-PR]Mathematics [math]/Probability [math.PR] ,régime alimentaire ,Socioeconomic Factors ,expenditure elasticity ,Energy Intake ,Compositional data - Abstract
International audience; This paper contributes to the analysis of the impact of socioeconomic factors, like food expenditure level and urbanization, on diet patterns in Vietnam, from 2004 to 2014. Contrary to the existing literature, we focus on the diet balance in terms of macronutrients consumption (protein, fat and carbohydrate) and we take into account the fact that the volumes of macronutrients are not independent. In other words, we are interested in the shares of each macronutrient in the total calorie intake. We use compositional data analysis (CODA), adapted to deal with the relative information contained in shares, to describe the evolution of diet patterns over time, and to model the impact of household characteristics on the macronutrient shares vector. We compute food expenditure elasticities of macronutrient shares, and we compare them to classical elasticities for macronutrient volumes and total calorie intake. The compositional model highlights the important role of many factors in the determination of diet choices and we will focus mainly on the role of food expenditure. Our results are consistent with the rest of the literature, but they have the advantage to highlight the substitution effects between macronutrients in the context of nutrition transition.
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- 2018
- Full Text
- View/download PDF
36. From Statistical Polymer Physics to Nonlinear Elasticity
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Cicalese, Marco, Gloria, Antoine, Ruf, Matthias, Cicalese, Marco, Gloria, Antoine, and Ruf, Matthias
- Abstract
A polymer-chain network is a collection of interconnected polymer-chains, made themselves of the repetition of a single pattern called a monomer. Our first main result establishes that, for a class of models for polymer-chain networks, the thermodynamic limit in the canonical ensemble yields a hyperelastic model in continuum mechanics. In particular, the discrete Helmholtz free energy of the network converges to the infimum of a continuum integral functional (of an energy density depending only on the local deformation gradient) and the discrete Gibbs measure converges (in the sense of a large deviation principle) to a measure supported on minimizers of the integral functional. Our second main result establishes the small temperature limit of the obtained continuum model (provided the discrete Hamiltonian is itself independent of the temperature), and shows that it coincides with the Γ -limit of the discrete Hamiltonian, thus showing that thermodynamic and small temperature limits commute. We eventually apply these general results to a standard model of polymer physics from which we derive nonlinear elasticity. We moreover show that taking the Γ -limit of the Hamiltonian is a good approximation of the thermodynamic limit at finite temperature in the regime of large number of monomers per polymer-chain (which turns out to play the role of an effective inverse temperature in the analysis)., SCOPUS: ar.j, info:eu-repo/semantics/published
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- 2020
37. R Libraries {dendextend} and {magrittr} and Clustering Package scipy.cluster of Python For Modelling Diagrams of Dendrogram Trees
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Lemenkova, Polina and Lemenkova, Polina
- Abstract
The paper presents a comparison of the two languages Python and R related to the classification tools and demonstrates the differences in their syntax and graphical output. It indicates the functionality of R and Python packages {dendextend} and scipy.cluster as effective tools for the dendrogram modelling by the algorithms of sorting and ranking datasets. R and Python programming languages have been tested on a sample dataset including marine geological measurements. The work aims to detect how bathymetric data change along the 25 bathymetric profiles digitized across the Mariana Trench. The methodology includes performed hierarchical cluster analysis with dendrograms and plotted clustermap with marginal dendrograms. The statistical libraries include Matplotlib, SciPy, NumPy, Pandas by Python and {dendextend}, {pvclust}, {magrittr} by R. The dendrograms were compared by the model-simulated clusters of the bathymetric ranges. The results show three distinct groups of the profiles sorted by the elevation ranges with maximal depths detected in a group of profiles 19-21. The dendrogram visualization in a cluster analysis demonstrates the effective representation of the data sorting, grouping and classifying by the machine learning algorithms. The programming codes presented in this study enable to sort a dataset in a similar research aimed to group data based on the similarity of attributes. Effective visualization by dendrograms is a useful modelling tool for the geospatial management where data ranking is required. Plotting dendrograms by R, comparing to Python, presented functional and sophisticated algorithms, refined design control and fine graphical data output. The interdisciplinary nature of this work consists in application of the coding algorithms for spatial data analysis., info:eu-repo/semantics/published
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- 2020
38. Mathematical modelling, analysis and simulations to improve the control of Miridae, a cocoa pest
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Djoukwe Tapi, Myriam Sonia and Djoukwe Tapi, Myriam Sonia
- Abstract
Cocoa is an important cash crop in Central and West Africa, especially in Cameroon. In this part of the world, cacao production is impacted by several diseases, like the Cocoa Swollen Shoot Virus (CSSV) and the black pod disease, and several pests, like Miridae, Distantiella theobroma and Sahlbergella singularis, causing significant damage to pods and vegetative parts of the cocoa tree, and thus impacting the cocoa production. However, the damage and losses associated with this pest remain difficult to estimate due in particular to the bio/ecology of this species (camouflage, low Statistical models have shown to be ineffective in describing these dynamics. That is why we have developed several Mathematical models to describe the time evolution dynamics of mirids, including the effect of different control methods. After an introductory chapter where we recall the biology and ecology of mirids, we develop, analyze and study a compartmental cooperative periodic and nonperiodic model in chapter 2. Then, considering time developments and sexual maturation duration for females, we develop and study a delayed cooperative model (with and without periodic parameters). In this latter model, we consider different control methods, including chemical control (insecticides) and semi-chemical control (sexual confusion and trapping). Through our numerical simulations, we recover recommendation given by mirid control organizations for the use of insecticides and show that chemical treatment can be replaced efficiently by mating disrupting and trapping. We also derive a global sensitivity analysis highlighting the importance of some key parameters. Then, based on the previous results, we develop, in chapter 3, a more complex delay model, modeling mating disrupting and trapping, using the piecewise-smooth system approach. Our analysis shows the existence of two thresholds based on mirid's biological parameters: one under which the control has no effect on established populations, and
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- 2020
39. Corrections to mean field for classical interacting particles
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Winter School "Turbulence in fluids and PDEs" (January 2020: EPFL, Lausanne), Duerinckx, Mitia, Winter School "Turbulence in fluids and PDEs" (January 2020: EPFL, Lausanne), and Duerinckx, Mitia
- Abstract
info:eu-repo/semantics/nonPublished
- Published
- 2020
40. Corrector Equations in Fluid Mechanics: Effective Viscosity of Colloidal Suspensions
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Duerinckx, Mitia, Gloria, Antoine, Duerinckx, Mitia, and Gloria, Antoine
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Consider a colloidal suspension of rigid particles in a steady Stokes flow. In a celebrated work, Einstein argued that in the regime of dilute particles the system behaves at leading order like a Stokes fluid with some explicit effective viscosity. In the present contribution, we rigorously define a notion of effective viscosity, regardless of the dilute regime assumption. More precisely, we establish a homogenization result for when particles are distributed according to a given stationary and ergodic random point process. The main novelty is the introduction and analysis of suitable corrector equations., SCOPUS: ar.j, info:eu-repo/semantics/published
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- 2020
41. Propagation of chaos and corrections to mean field for classical interacting particles
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Workshop "Classical and Quantum Mechanical Models of Many-Particle Systems" (December 2020: Oberwolfach), Duerinckx, Mitia, Workshop "Classical and Quantum Mechanical Models of Many-Particle Systems" (December 2020: Oberwolfach), and Duerinckx, Mitia
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info:eu-repo/semantics/nonPublished
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- 2020
42. Construction of a solution for the two-component radial Gross-Pitaevskii system with a large coupling parameter
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Casteras, Jean-Baptiste, Sourdis, Christos, Casteras, Jean-Baptiste, and Sourdis, Christos
- Abstract
We consider strongly coupled competitive elliptic systems that arise in the study of two-component Bose-Einstein condensates. As the coupling parameter tends to infinity, solutions that remain uniformly bounded are known to converge to a segregated limiting profile, with the difference of its components satisfying a limit scalar PDE. In the case of radial symmetry, under natural non-degeneracy assumptions on a solution of the limit problem, we establish by a perturbation argument its persistence as a solution to the elliptic system., SCOPUS: ar.j, DecretOANoAutActif, info:eu-repo/semantics/published
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- 2020
43. Obstructions for symplectic lie algebroids
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Klaasse, Ralph and Klaasse, Ralph
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Several types of generically-nondegenerate Poisson structures can be effectively studied as symplectic structures on naturally associated Lie algebroids. Relevant examples of this phenomenon include log-, elliptic, bk-, scattering and elliptic-log Poisson structures. In this paper we discuss topological obstructions to the existence of such Poisson structures, obtained through the characteristic classes of their associated symplectic Lie algebroids. In particular we obtain the full obstructions for surfaces to carry such Poisson structures., SCOPUS: ar.j, DecretOANoAutActif, info:eu-repo/semantics/published
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- 2020
44. On the asymptotic Dirichlet problem for a class of mean curvature type partial differential equations
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Bonorino, Leonardo, Casteras, Jean-Baptiste, Klaser, Patricia, Ripoll, Jaime Bruck, Telichevesky, Miriam, Bonorino, Leonardo, Casteras, Jean-Baptiste, Klaser, Patricia, Ripoll, Jaime Bruck, and Telichevesky, Miriam
- Abstract
We study the Dirichlet problem for the following prescribed mean curvature PDE {-div∇v1+, SCOPUS: ar.j, DecretOANoAutActif, info:eu-repo/semantics/published
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- 2020
45. Robustness of the pathwise structure of fluctuations in stochastic homogenization
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Duerinckx, Mitia, Gloria, Antoine, Otto, Felix, Duerinckx, Mitia, Gloria, Antoine, and Otto, Felix
- Abstract
We consider a linear elliptic system in divergence form with random coefficients and study the random fluctuations of large-scale averages of the field and the flux of the solution operator. In the context of the random conductance model, we developed in a previous work a theory of fluctuations based on the notion of homogenization commutator: we proved that the two-scale expansion of this special quantity is accurate at leading order in the fluctuation scaling when averaged on large scales (as opposed to the two-scale expansion of the solution operator taken separately) and that the large-scale fluctuations of the field and the flux of the solution operator can be recovered from those of the commutator. This implies that the large-scale fluctuations of the commutator of the corrector drive all other large-scale fluctuations to leading order, which we refer to as the pathwise structure of fluctuations in stochastic homogenization. In the present contribution we extend this result in two directions: we treat continuum elliptic (possibly non-symmetric) systems and allow for strongly correlated coefficient fields (Gaussian-like with a covariance function that can display an arbitrarily slow algebraic decay at infinity). Our main result shows in this general setting that the two-scale expansion of the homogenization commutator is still accurate to leading order when averaged on large scales, which illustrates the robustness of the pathwise structure of fluctuations., SCOPUS: ar.j, info:eu-repo/semantics/published
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- 2020
46. Defining the molecular and cellular mechanisms underlying wound repair and postnatal growth in the mouse epidermis
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Blanpain, Cédric, Brion, Jean Pierre, Richert, Bertrand, Parmentier, Marc, Franchimont, Denis, Jensen, Kim Bak, Itzkovitz, Shalev S.I., Dekoninck, Sophie, Blanpain, Cédric, Brion, Jean Pierre, Richert, Bertrand, Parmentier, Marc, Franchimont, Denis, Jensen, Kim Bak, Itzkovitz, Shalev S.I., and Dekoninck, Sophie
- Abstract
The epidermis is the first barrier of protection of living organisms against external attacks. It is constantly renewed throughout life, through a process called "homeostasis", which ensures that every cell lost on its surface is replaced by new ones. Recent studies have shown that this balance is ensured by a hierarchy of stem cells (SC) and progenitors that perform 3 types of cell divisions, each having a fixed probability. Although the epidermis has been extensively studied during homeostasis, little is known about the cellular dynamics taking place when the epidermis must expand its surface. Are these probabilities of division immutable or can they change? In this project, we focused on two conditions of epidermal expansion: postnatal growth and wound healing. Using the mouse tail epidermis as a model, we show that the re-epithelialization after a wound is achieved via the formation of two transient compartments that are spatially and molecularly distinct :a leading edge and a proliferative hub. We show that the leading edge cells have a specific transcriptional signature that is independent of their quiescent state and we propose new markers not previously described. Using the technique of "lineage tracing", coupled with clonal analysis and mathematical modeling, we highlight the proliferation dynamics of SCs and progenitors during healing. We show that different populations of cells residing in different compartments, the hair follicle infundibulum and the interfollicular epidermis, acquire a similar dynamics and re-activate their SC while the progenitors increase their rate of proliferation without changing their division probabilities. This similar proliferation dynamics in two compartments of the epidermis suggests that division probabilities are not dictated by the cell of origin. Interestingly, cell dynamics is different during postnatal growth. Using lineage tracing, clonal analysis and single-cell transcriptional analysis, we demonstrate that the post-n, L’épiderme est la première barrière de protection des organismes vivants contre des attaques extérieures. Il est constamment renouvelé au cours de la vie, via un processus appelé « homeostasie », qui assure que chaque cellule perdue à sa surface soit remplacée par de nouvelles. Des études récentes ont montré que cet équilibre était assuré par une hiérarchie de cellules souches (CS) et de progéniteurs qui réalisent 3 types de divisions cellulaires, chaque type de division ayant une probabilité fixe. Bien que l’épiderme ait été intensivement étudié durant l’homeostasie, peu de choses sont connues concernant la dynamique cellulaire prenant place lors de phénomènes où l’épiderme doit grandir. Ces probabilités de division sont-elles immuables ou peuvent-elles au contraire changer ?Dans ce projet, nous nous sommes intéressés à deux conditions d’expansion de l’épiderme :la croissance post-natale et la cicatrisation des plaies. En utilisant l’épiderme de la queue de souris comme modèle, nous montrons que la ré-épithélialisation d’une plaie est réalisée via la formation de deux compartiments cellulaires transitoires distincts spatialement et du point de vue moléculaire :un front de migration et un centre prolifératif. Nous montrons que les cellules du front de migration ont une signature transcriptionnelle spécifique qui est indépendante de leur état de quiescence et proposons de nouveaux marqueurs non décrits auparavant. En utilisant la technique du « lineage tracing », couplée à une analyse clonale et à de la modélisation mathématique, nous mettons en évidence la dynamique de prolifération des CS et des progéniteurs lors de la cicatrisation. Nous montrons que différentes populations de cellules résidant dans des compartiments différents, l’infundibulum du follicule pileux et l’épiderme interfolliculaire, acquièrent une dynamique similaire et ré-activent leur CS tandis que les progéniteurs augmentent leur taux de prolifération sans changer leur probabilité de division. Cett, Doctorat en Sciences biomédicales et pharmaceutiques (Pharmacie), info:eu-repo/semantics/nonPublished
- Published
- 2020
47. New concentration phenomena for a class of radial fully nonlinear equations
- Author
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Galise, Giulio, Iacopetti, Alessandro, Leoni, Fabiana, Pacella, Filomena, Galise, Giulio, Iacopetti, Alessandro, Leoni, Fabiana, and Pacella, Filomena
- Abstract
We study radial sign-changing solutions of a class of fully nonlinear elliptic Dirichlet problems in a ball, driven by the extremal Pucci's operators and with a power nonlinear term. We first determine a new critical exponent related to the existence or nonexistence of such solutions. Then we analyze the asymptotic behavior of the radial nodal solutions as the exponents approach the critical values, showing that new concentration phenomena occur. Finally we define a suitable weighted energy for these solutions and compute its limit value., SCOPUS: ar.j, info:eu-repo/semantics/published
- Published
- 2020
48. Liouville-type results in exterior domains for radial solutions of fully nonlinear equations
- Author
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Galise, Giulio, Iacopetti, Alessandro, Leoni, Fabiana, Galise, Giulio, Iacopetti, Alessandro, and Leoni, Fabiana
- Abstract
We give necessary and sufficient conditions for the existence of positive radial solutions for a class of fully nonlinear uniformly elliptic equations posed in the complement of a ball in RN, and equipped with homogeneous Dirichlet boundary conditions., SCOPUS: ar.j, info:eu-repo/semantics/published
- Published
- 2020
49. The Structure of Fluctuations in Stochastic Homogenization
- Author
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Duerinckx, Mitia, Gloria, Antoine, Otto, Felix, Duerinckx, Mitia, Gloria, Antoine, and Otto, Felix
- Abstract
Four quantities are fundamental in homogenization of elliptic systems in divergence form and in its applications: the field and the flux of the solution operator (applied to a general deterministic right-hand side), and the field and the flux of the corrector. Homogenization is the study of the large-scale properties of these objects. In case of random coefficients, these quantities fluctuate and their fluctuations are a priori unrelated. Depending on the law of the coefficient field, and in particular on the decay of its correlations on large scales, these fluctuations may display different scalings and different limiting laws (if any). In this contribution, we identify another crucial intrinsic quantity, motivated by H-convergence, which we refer to as the homogenization commutator and is related to variational quantities first considered by Armstrong and Smart. In the simplified setting of the random conductance model, we show what we believe to be a general principle, namely that the homogenization commutator drives at leading order the fluctuations of each of the four other quantities in a strong norm in probability, which is expressed in form of a suitable two-scale expansion and reveals the pathwise structure of fluctuations in stochastic homogenization. In addition, we show that the (rescaled) homogenization commutator converges in law to a Gaussian white noise, and we analyze to which precision the covariance tensor that characterizes the latter can be extracted from the representative volume element method. This collection of results constitutes a new theory of fluctuations in stochastic homogenization that holds in any dimension and yields optimal rates. Extensions to the (non-symmetric) continuum setting are also discussed, the details of which are postponed to forthcoming works., SCOPUS: ar.j, info:eu-repo/semantics/published
- Published
- 2020
50. Higher-order pathwise theory of fluctuations in stochastic homogenization
- Author
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Duerinckx, Mitia, Otto, Felix, Duerinckx, Mitia, and Otto, Felix
- Abstract
We consider linear elliptic equations in divergence form with stationary random coefficients of integrable correlations. We characterize the fluctuations of a macroscopic observable of a solution to relative order d2, where d is the spatial dimension; the fluctuations turn out to be Gaussian. As for previous work on the leading order, this higher-order characterization relies on a pathwise proximity of the macroscopic fluctuations of a general solution to those of the (higher-order) correctors, via a (higher-order) two-scale expansion injected into the “homogenization commutator”, thus confirming the scope of this notion. This higher-order generalization sheds a clearer light on the algebraic structure of the higher-order versions of correctors, flux correctors, two-scale expansions, and homogenization commutators. It reveals that in the same way as this algebra provides a higher-order theory for microscopic spatial oscillations, it also provides a higher-order theory for macroscopic random fluctuations, although both phenomena are not directly related. We focus on the model framework of an underlying Gaussian ensemble, which allows for an efficient use of (second-order) Malliavin calculus for stochastic estimates. On the technical side, we introduce annealed Calderón–Zygmund estimates for the elliptic operator with random coefficients, which conveniently upgrade the known quenched large-scale estimates., SCOPUS: ar.j, info:eu-repo/semantics/published
- Published
- 2020
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