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Neonatal seizures are a significant contributor to neonatal morbidity and mortality in Nigeria and the magnitude of the burden is unknown. A comprehensive systematic review is needed to determine the pooled magnitude and causes of neonatal seizures in Nigeria since the true estimate is yet to be determined. Therefore, this study aims to develop a protocol to assess the burden and causes of neonatal seizures in Nigeria. A search strategy is developed using MeSH terms, text words, and entry terms. Nine databases will be searched including Pub- Med, African journals online, Google Scholar, Cumulative Index to Nursing and Allied Health Literature, EMBASE, Psych Info, Web of Science, Scopus, and Research Gate. Only observational studies, retrievable in the English language and conducted in Nigerian neonates will be included. The primary outcome of this study is the pooled prevalence of neonatal seizures in Nigeria. The secondary outcomes include the seizure types, causes, method of detection, and outcome in the neonates. Screening of identified studies will be done in End Note version 20 and duplicates removed, before exporting to Microsoft 365 excel sheet for data extraction by independent reviewers. Studies will be assessed for methodological, clinical, and statistical heterogeneity and if required, a meta-analysis will be done. Stata 16 IC will be used for data analysis. Various subgroup analyses will also be done. A funnel plot will be used for the assessment of publication bias. Results will be presented in tabular formats, narrative synthesis, and regression plots. The data from this review will reveal the pooled prevalence of neonatal seizures in Nigeria. It will create an avenue for discussion on the types, causes, and outcome of neonatal seizures. The findings will also enable discussions on how to address the causes of neonatal seizures in Nigeria and provide evidence for policy recommendations to reduce morbidity and mortality resulting from neonatal seizures in Nigeria. Trial registration number: This protocol is registered in PROSPERO with registration number CRD42020220097.

Background: Information on the effects of the coronavirus pandemic on adolescents and young people, who are in a critical phase of transition to adulthood is sparse. We evaluated the effects of coronavirus disease (COVID-19) among adolescents and young people living in Southeast Nigeria.Objective: To evaluate the effects of the coronavirus pandemic on young people in NigeriaMethods: A cross-sectional (online and onsite) study of 328 Nigerian youths was conducted, and data on sociodemographic profile and effects of the pandemic collected through pre-tested self-administered questionnaires, were analysed using STATA 16.0, with the significance level for tests of association set at p

Background: Helicobacter pylori is a common cause of infection among humans. The organism is usually acquired in childhood but may persist into adulthood resulting in chronic gastritis, peptic ulcer disease and adenocarcinoma. Aim: To determine the seroprevalence and risk factors of H. pylori infection among children seen at the Paediatric Out-Patient Clinic of a tertiary teaching hospital in South- East, Nigeria. Methods: It was a cross-sectional study carried out among 248 children aged between 1 and 18 years seen at the Paediatric Outpatient Clinic at the tertiary hospital from August 2017 to October 2017. Information on socio-demographics, feeding practices, daycare attendance and vaccination were obtained and entered into a proforma. The serum obtained from the patient was tested for H. pylori antibodies. Results: The seroprevalence of H. pylori infection among the subjects was 36.3%. Statistically significant association was found between age of the subjects, parental education, social class, ingestion of uncooked/ raw food materials and H. pylori infection (p < 0.05). On logistic regression analysis, predictors of H. pylori infection were age 6-12 years (AOR = 2.42, 95% CI = 1.31-4.47, p = 0.005) and ingestion of uncooked/raw food materials (AOR= 2.38, 95% CI 1.14-8.33, p = 0.022). Conclusion: Risk factors associated with H. pylori infection include age, parental education, social class and ingestion of uncooked or raw food materials.