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Influence of two filtering modes were researched with electro-oculographically recorded impulse-like eye movements. Linear finite impulse response (FIR) and non-linear hybrid median filters were explored by considering gain and latency parameters that yield the most important information in the case of these eye movements. It is stated that carefully selected lowpass filtering can securely be run without considerable changes in parameter values in order to discard noise stemming from physiological or other reasons. [ABSTRACT FROM AUTHOR]

Military personnel needs to be resilient to be able to remain effective, motivated, and in good mental and physical health. Military organizations select on resilience to determine whether candidates are psychologically fit for their job. The INSPIRE Resilience Scale (IRS) is such a selection instrument that aims to assess the psychological resilience potential of candidates in high-risk professions. A longitudinal predictive validity study was conducted in five European Defense organizations and in the Dutch National Police. The IRS was submitted in selection (N = 11,404), and criterion data about performance and health were collected in the second half of the first training year (N = 726). The results based on correlational and regression analyses showed that the IRS scores significantly predicted the criterion measures. Emotional stability, part of the IRS, turned out to be the best predictor. Results also showed that candidates who dropped out of training had significantly lower means on the IRS in selection than candidates who were still in training in the second half of the first training year. Overall, the IRS proved to be a valid instrument to assess resilience potential in candidates for high-risk professions. Selecting on resilience may therefore contribute to training success and reduction of health problems.

Molecular imaging is the future of personalized medicine; however, it requires effective contrast agents. Hyperpolarized chemical exchange saturation transfer (HyperCEST) can boost the signal of Hyperpolarized 129 Xe MRI and render it a molecular imaging modality of high efficiency. Cucurbit[6]uril (CB6) has been successfully employed in vivo as a contrast agent for HyperCEST MRI, however its performance in a clinical MRI scanner has yet to be optimized. In this study, MRI pulse sequence parameter optimization was first performed in CB6 solutions in phosphate-buffered saline (PBS), and subsequently in whole sterile citrated bovine blood. The performance of four different depolarization pulse shapes (sinusoidal, 3-lobe sinc (3LS), rectangular (block), and hyperbolic secant (hypsec) was optimized. The detectability limits of CB6 in a clinical 3.0T MRI scanner was assessed using the optimized pulse sequences. The 3LS depolarization pulses performed best, and demonstrated 24 % depletion in a 25 μM solution of CB6 in PBS. It performed similarly in blood. The CB6 detectability limit was found to be 100 μM in citrated bovine blood with a correspondent HyperCEST depletion of 30 % ±9 %. For the first time, the HP 129 Xe HyperCEST effect was observed in red blood cells (RBC) and had a similar strength as HyperCEST in plasma., (© 2023 The Authors. ChemPhysChem published by Wiley-VCH GmbH.)