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2. Grade V renal trauma management: results from the multi-institutional genito-urinary trauma study.

Author

Hakam, Nizar, Keihani, Sorena, Shaw, Nathan M, Abbasi, Behzad, Jones, Charles P, Rogers, Douglas, Wang, Sherry S, Gross, Joel A, Joyce, Ryan P, Hagedorn, Judith C, Selph, J Patrick, Sensenig, Rachel L, Moses, Rachel A, Dodgion, Christopher M, Gupta, Shubham, Mukherjee, Kaushik, Majercik, Sarah, Smith, Brian P, Broghammer, Joshua A, Schwartz, Ian, Baradaran, Nima, Zakaluzny, Scott A, Erickson, Bradley A, Miller, Brandi D, Askari, Reza, Carrick, Matthew M, Burks, Frank N, Norwood, Scott, Myers, Jeremy B, Breyer, Benjamin N, and Multi-institutional Genito-Urinary Trauma Study Group (MiGUTS)

Subjects
Multi-institutional Genito-Urinary Trauma Study Group, Urogenital System, Kidney, Humans, Multiple Trauma, Nephrectomy, Injury Severity Score, Retrospective Studies, Adult, Middle Aged, Trauma Centers, Kidney trauma, Nonoperative management, Urologic trauma, Kidney Disease, Physical Injury - Accidents and Adverse Effects, Patient Safety, 6.4 Surgery, Evaluation of treatments and therapeutic interventions, Clinical Sciences, Urology & Nephrology
Abstract

PurposeTo investigate management trends for American Association for the Surgery of Trauma (AAST) grade V renal trauma with focus on non-operative management.MethodsWe used prospectively collected data as part of the Multi-institutional Genito-Urinary Trauma Study (MiGUTS). We included patients with grade V renal trauma according to the AAST Injury Scoring Scale 2018 update. All cases submitted by participating centers with radiology images available were independently reviewed to confirm renal trauma grade. Management was classified as expectant, conservative (minimally invasive, endoscopic or percutaneous procedures), or operative (renal-related surgery).ResultsEighty patients were included, 25 of whom had complete imaging and had independent confirmation of AAST grade V renal trauma. Median age was 35 years (Interquartile range (IQR) 25-50) and 23 (92%) had blunt trauma. Ten patients (40%) were managed operatively with nephrectomy. Conservative management was used in nine patients (36%) of which six received angioembolization and three had a stent or drainage tube placed. Expectant management was followed in six (24%) patients. Transfusion requirements were progressively higher with groups requiring more aggressive treatment, and injury characteristics differed significantly across management groups in terms of hematoma size and laceration size. Vascular contrast extravasation was more likely in operatively managed patients though a statistically significant association was not found.ConclusionSuccessful use of nonoperative management for grade V injuries is used for a substantial subset of patients. Lower transfusion requirement and less severe injury radiologic phenotype appear to be important characteristics delineating this group.

Published
2023

3. Radiation-induced Fistulas in Patients With Prior Pelvic Radiotherapy for Prostate Cancer: A Systematic Review and Meta-analysis.

Author

Sadighian, Michael, Hakam, Nizar, Amend, Gregory, Shaw, Nathan M, Tahir, Peggy, Allen, Isabel E, Nabavizadeh, Behnam, Holler, Jordan, Shibley, William, Li, Kevin D, Abbasi, Behzad, Bell, Alexander, Mohamad, Osama, and Breyer, Benjamin N

Subjects
Pelvis, Humans, Prostatic Neoplasms, Cohort Studies, Male, Prevention, Digestive Diseases, Prostate Cancer, Cancer, Urologic Diseases, Clinical Sciences, Urology & Nephrology
Abstract

ObjectiveTo systematically aggregate and summarize existing data on fistula prevalence among patients with a history of pelvic radiotherapy for prostate cancer.Materials and methodsWe queried PubMed, Embase, and Web of Science on October 7, 2020 for peer-reviewed publications pertaining to radiation-induced fistulas in the pelvis. For meta-analysis, we used the random-effects model. We used the I2 statistic to quantify heterogeneity and the Newcastle-Ottawa Scale to assess risk of bias.ResultsOur final meta-analysis included 6 cohort studies with a total of 7665 patients exposed to pelvic radiotherapy between 1967 and 2013. Median follow-up time was 35.5 months (IQR 33.5-57.5). Pooled prevalence of radiation-induced fistula across all 6 cohort studies was 0.2% (95% CI: 0.1-0.4, I2 = 0.000%, P < .608). In subgroup analysis, we did not detect significant heterogeneity in fistula prevalence in patients who were re-irradiated (0.3%, 95% CI: 0.1-0.4; P = .762) or patients on concurrent chemotherapy (0.4%, 95% CI: -0.3 -1.2; P = .664) compared to those receiving their first course of radiotherapy alone. No randomized controlled trials met inclusion criteria due to ambiguous and inconsistent reporting language for fistula occurrence.ConclusionThere is limited published literature reporting fistula as an adverse event of prostate cancer radiotherapy, especially in the medium and long-term period. Patients undergoing pelvic radiotherapy for prostate cancer appear at low short-term risk for developing fistulas. Adverse event reporting in randomized controlled trials merits greater granularity where fistulas should be reported with specificity rather than aggregating into broad categories of genitourinary or gastrointestinal adverse events.

Published
2023

4. The Impact of Patient Travel Distance on Outpatient Visit Satisfaction: Comparison of Telehealth and Traditional In-Person Visits

Author

Shaw, Nathan M, Abbasi, Behzad, Odisho, Anobel Y, Hills, Nancy, Holler, Jordan, Sliwka, Diane, and Breyer, Benjamin N

Subjects
Clinical Research, 7.1 Individual care needs, Management of diseases and conditions, Good Health and Well Being, patient satisfaction, telemedicine, telehealth, Library and Information Studies, Biomedical Engineering, Public Health and Health Services, Medical Informatics
Abstract

Introduction: Patient satisfaction has been shown to changes based on the distance a patient to see their physician. We sought to examine the effects of telehealth on patient satisfaction. Methods: We examined patient satisfaction survey scores from outpatient clinics at University of California, San Francisco. Patient home and clinic addresses were used to calculate distance in kilometers (km). Outcomes were "top scores (9-10)" and "low scores (100 km for in-person visits had more top scores (84%) than those traveled 100 km had the highest odds of top score for telehealth (OR: 1.86). Conclusions: Patients receiving care through telehealth, particularly those far from the outpatient clinic, are more likely to provide high patient satisfaction scores for the visit provider.

Published
2023

5. Adverse reactions of PDE5 inhibitors: An analysis of the World Health Organization pharmacovigilance database.

Author

Lui, Jason L, Shaw, Nathan M, Abbasi, Behzad, Hakam, Nizar, and Breyer, Benjamin N

Subjects
PDE5 inhibitor, erectile dysfunction, malignant melanoma, priapism, sexual dysfunction, sildenafil, Cancer, Clinical Research, Patient Safety, Evaluation of treatments and therapeutic interventions, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, 6.1 Pharmaceuticals, Genetics, Clinical Sciences, Paediatrics and Reproductive Medicine
Abstract

BackgroundDespite their efficacy and general safety, rare but devastating adverse drug reactions have been associated with phosphodiesterase type 5 inhibitors.ObjectivesTo determine the safety profile of oral phosphodiesterase type 5 inhibitors with a particular focus on priapism and malignant melanoma.Materials and methodsIn this case-non-case study, we queried the individual case safety reports for phosphodiesterase type 5 inhibitors within the World Health Organization global database of individual case safety reports (VigiBase) between 1983 and 2021. We included all individual case safety reports for sildenafil, tadalafil, vardenafil, and avanafil in men. For comparison, we also extracted the safety data from the Food and Drug Administration trials for these drugs. We assessed the safety profile of phosphodiesterase type 5 inhibitors by disproportionality analysis by measuring reporting odds ratio for their most commonly reported adverse drug reactions, once for all phosphodiesterase type 5 inhibitor reports and once for reports of oral phosphodiesterase type 5 inhibitor use in adult men (≥18 years old) with sexual dysfunction.ResultsA total of 94,713 individual case safety reports for phosphodiesterase type 5 inhibitors were extracted. A total of 31,827 individual case safety reports were identified relating to adult men taking oral sildenafil, tadalafil, vardenafil, or avanafil for sexual dysfunction. The most common adverse drug reactions included poor drug efficacy (42.5%), headache (10.4% vs. 8.5%-27.6% [Food and Drug Administration]), abnormal vision (8.4% vs. ≤4.6% [Food and Drug Administration]), flushing (5.2% vs. 5.1%-16.5% [Food and Drug Administration]), and dyspepsia (4.2% vs. 3.4%-11.1% [Food and Drug Administration]). Priapism showed significant signals for sildenafil (reporting odds ratio = 13.81, 95% confidence interval: 11.75-16.24), tadalafil (reporting odds ratio = 14.54, 95% confidence interval: 11.56-18.06), and vardenafil (reporting odds ratio = 14.12, 95% confidence interval: 8.36-22.35). Comparing with other medications in VigiBase, sildenafil (reporting odds ratio = 8.73, 95% confidence interval: 7.63-9.99) and tadalafil (reporting odds ratio = 4.25, 95% confidence interval: 3.19-5.55) had significantly higher reporting odds ratios for malignant melanoma.ConclusionPhosphodiesterase type 5 inhibitors show significant signals correlating with priapism among a large international cohort. Further clinical study is needed to elucidate whether this is from proper or inappropriate use or other confounding conditions, as analysis of pharmacovigilance data does not allow for quantifying the clinical risk. Also, there appears to be a relationship between phosphodiesterase type 5 inhibitor use and malignant melanoma, which warrants additional study to better understand causation.

Published
2023

6. Role for Conservative Management in Grade V Renal Trauma

Author

Hakam, Nizar, Shaw, Nathan M, Lui, Jason, Abbasi, Behzad, Myers, Jeremy B, and Breyer, Benjamin N

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Clinical Research, Kidney Disease, Physical Injury - Accidents and Adverse Effects, Good Health and Well Being, Humans, Conservative Treatment, Retrospective Studies, Kidney, Wounds, Penetrating, Trauma Centers, Wounds, Nonpenetrating, acute kidney injury, conservative treatment, nephrectomy, Urology & Nephrology, Clinical sciences
Abstract

PurposeWe assessed the use of conservative management for American Association for the Surgery of Trauma grade V renal trauma in the National Trauma Databank.Materials and methodsWe used data of grade V renal trauma patients in the 2017-2019 National Trauma Databank. Conservative management was defined by the absence of surgical or procedural intervention except for ureteral stent or percutaneous drain placement. We initially analyzed patients who survived to final hospital discharge and reported the percent utilization of conservative management. We then repeated our analysis in the overall grade V population and in all those who did not die in the emergency department.ResultsOf 1,474 who survived to discharge, 557 (37.8%) patients were managed conservatively. In the adjusted analysis, penetrating trauma mechanism (OR 0.13, 95% CI 0.09-0.19, P < .001) and receiving transfusion (OR 0.22, 95% CI 0.17-0.29, P < .001) were associated with decreased odds of receiving conservative management. Overall, there were 1,919 patients with grade V injury, of whom 731 (38.1%) were managed conservatively. Mortality rate was 22.8% in those managed conservatively vs 23.8% in those who had intervention. After excluding 110 patients who died in the emergency department, there were 1,809 patients, of whom 625 (34.6%) were managed conservatively. Mortality rate was 22.6% in the operatively managed group and 10.9% in the conservatively managed group.ConclusionsA substantial portion of grade V renal trauma cases were managed successfully without intervention in the National Trauma Databank. Further research is needed to identify radiological phenotypes suitable for nonoperative management and to overcome possible renal trauma grade misclassification.

Published
2023

7. Online medical crowdfunding in the United States: a cross-sectional analysis of gendered cancer campaign outcomes

Author

Holler, Jordan T, Sadighian, Michael J, Ghaffar, Umar, Abbasi, Behzad, Nabavizadeh, Behnam, Hakam, Nizar, Li, Kevin, Shibley, William, Leapman, Michael S, Amend, Gregory M, Shaw, Nathan M, and Breyer, Benjamin N

Subjects
Ovarian Cancer, Rare Diseases, Urologic Diseases, Aging, Cancer, Cervical Cancer, Prostate Cancer, Breast Cancer, Cancer treatment, Crowdfunding, Gender differences, Breast cancer, Social media, Male cancer, Medical and Health Sciences
Abstract

This cross-sectional analysis examined online US crowdfunding campaigns from 2010–2018. Campaigns including prostate, breast, bladder, kidney, cervical, uterine, ovarian, testicular, oral, and thyroid cancers were included. Multivariable modeling was utilized to examine predictive factors for successful campaigns. A total of 1830 online cancer campaigns were included in the final analysis. Breast cancer was estimated to be the most frequent online campaign type (n = 3682), followed by cervical (n = 492), kidney (n = 475), ovarian (n = 460), and prostate cancers (n = 382). Breast cancer campaigns generated the most total funding ($15.3 million). In adjusted models, breast cancers generated significantly more donations per campaign than any other cancer. There was no difference in the average amount of funds raised per campaign by most cancer types, except for thyroid (19.4% less than breast, p < 0.001). Friend-authored campaigns generated more funding than self- and family-authored. Male cancers are under-represented, and breast cancer campaigns are disproportionately over-represented in online medical crowdfunding and generate more donations than many other cancers. Gendered differences in cancer crowdfunding are likely multifactorial and may be influenced by social networks and public health campaigns.

Published
2023

10. Impact of the COVID-19 pandemic on emergency department visits for genitourinary trauma

Author

Nabavizadeh, Behnam, Hakam, Nizar, Abbasi, Behzad, Shaw, Nathan M, and Breyer, Benjamin N

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Emergency Care, Prevention, Physical Injury - Accidents and Adverse Effects, Infectious Diseases, Injuries and accidents, Good Health and Well Being, Adult, COVID-19, Child, Communicable Disease Control, Emergency Service, Hospital, Female, Humans, Male, Pandemics, Retrospective Studies, United States, Genitourinary, Trauma, Pandemic, Urology & Nephrology, Clinical sciences
Abstract

IntroductionThe mean number of emergency department visits for all-cause traumas has declined significantly during the COVID-19 pandemic. We aim to identify how a global pandemic and social distancing could affect the trends and pattern of genitourinary traumas.MethodsWe queried the National Electronic Injury Surveillance System to obtain consumer product-related genitourinary injuries leading to emergency department visits. Using three key events in 2020, we divided the study period to three intervals: January 20, when the first COVID-19 case was confirmed in the United States; March 13, when a national state of emergency was declared; April 20, when Texas became the first state to start a phased reopening of economy. We compared the injury characteristics in 2020 to their identical intervals in 2019.ResultsDaily emergency department visits dropped significantly during the national lockdown (mean 131.5 vs. 78; Δ-40.7%; p

Published
2022

11. Alcohol Intoxication Is Associated With Bladder Injury and Bladder Surgical Repair in Patients Sustaining Motor Vehicle Collisions

Author

Lui, Jason L, Hakam, Nizar, Shaw, Nathan M, Cuschieri, Joseph, Abbasi, Behzad, and Breyer, Benjamin N

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Alcoholism, Alcohol Use and Health, Urologic Diseases, Clinical Research, Physical Injury - Accidents and Adverse Effects, Substance Misuse, Injuries and accidents, Good Health and Well Being, Abdominal Injuries, Accidents, Traffic, Alcoholic Intoxication, Blood Alcohol Content, Ethanol, Humans, Motor Vehicles, Urinary Bladder, Urinary Bladder Diseases, Wounds and Injuries, alcoholic intoxication, wounds and injuries, Urology & Nephrology, Clinical sciences
Abstract

PurposeAlcohol intoxication is a known risk factor for motor vehicle collisions. We hypothesize ethanol intoxication increases the risk of bladder injury and surgical repair, especially at higher blood alcohol content levels.Materials and methodsWe identified all patients involved in motor vehicle collisions from the National Trauma Data Bank from 2017-2019. Patients were categorized into an intoxication and intoxication negative group. Variables collected included age, sex, blood alcohol content level, driver status, seat belt restraint use, nonalcoholic intoxication, pelvic fracture, and Injury Severity Scale. Primary outcome measures of bladder injury and bladder surgical repair were assessed and interaction with pelvic fracture and restraint use were measured.ResultsWe identified 594,484 patients and 97,831 (16.5%) had a positive alcohol screen. Patients in the intoxication group were more likely to be intoxicated with other substances (32.8% vs 14.6%, P < .001), have a bladder injury (1% vs 0.4%, P < .001) and receive bladder surgical repair (0.7% vs 0.15%, P < .001). Injury Severity Scale and pelvic fracture were statistically significant predictors of bladder injury. In adjusted analysis, higher blood alcohol content was associated with both outcomes. Above the legal limit, alcohol intoxication was more predictive of bladder surgical repair than pelvic fracture. The association of alcohol intoxication with both outcomes did not differ by pelvic fracture, but strengthened with seat belt use at higher intoxication levels.ConclusionsAlcohol intoxication is independently associated with increased risk of bladder injury and subsequent bladder surgical repair following motor vehicle collisions. Trauma providers should have a high index of suspicion for bladder injuries in alcohol intoxicated patients, particularly those using seat belt restraints.

Published
2022

12. Posterior urethral stenosis: a comparative review of the guidelines

Author

Abbasi, Behzad, Shaw, Nathan M, Lui, Jason L, Li, Kevin D, Sudhakar, Architha, Low, Patrick, Hakam, Nizar, Nabavizadeh, Behnam, and Breyer, Benjamin N

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Urologic Diseases, Humans, Male, Urethral Stricture, Urethra, Constriction, Pathologic, Urology, Urologic Surgical Procedures, Male, Urethral stricture, Urethral stenosis, Posterior, Bladder neck contracture, Vesico-urethral anastomotic stenosis, Pelvic fracture urethral injury, Urology & Nephrology, Clinical sciences
Abstract

PurposeWe aimed to provide a thorough comparative review of the available guidelines on the diagnosis, management, and follow-up for patients with posterior urethral stenosis by the American Urologic Association (2016), Société Internationale d'Urologie (2010), and European Urologic Association (2022).MethodsThe AUA, SIU, and EAU guidelines were evaluated for recommendations on the diagnosis, evaluation, and treatment of posterior urethral stenosis. We also included the EAU and AUA urologic trauma guidelines for the trauma-related stenosis. The level or strength of recommendations is included in case of disparity between the guidelines.ResultsThe three guidelines align considerably in recommendations provided for the diagnosis, management, and follow-up of patients with posterior urethral stenosis. SIU and EAU emphasize the role of repeat endoscopic treatment in guidelines compared to AUA.ConclusionThe preferred method to repair bulbo-membranous stricture/stenosis following radiation therapy remains an area of active interest, focusing on continence preservation. Additionally, there may be a role for advanced endoscopic treatments with or without adjunct therapies to manage even obliterated stenoses.

Published
2022

13. The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019

Author

Collaborators, GBD 2019 Cancer Risk Factors, Tran, Khanh Bao, Lang, Justin J, Compton, Kelly, Xu, Rixing, Acheson, Alistair R, Henrikson, Hannah Jacqueline, Kocarnik, Jonathan M, Penberthy, Louise, Aali, Amirali, Abbas, Qamar, Abbasi, Behzad, Abbasi-Kangevari, Mohsen, Abbasi-Kangevari, Zeinab, Abbastabar, Hedayat, Abdelmasseh, Michael, Abd-Elsalam, Sherief, Abdelwahab, Ahmed Abdelwahab, Abdoli, Gholamreza, Abdulkadir, Hanan Abdulkadir, Abedi, Aidin, Abegaz, Kedir Hussein, Abidi, Hassan, Aboagye, Richard Gyan, Abolhassani, Hassan, Absalan, Abdorrahim, Abtew, Yonas Derso, Ali, Hiwa Abubaker, Abu-Gharbieh, Eman, Achappa, Basavaprabhu, Acuna, Juan Manuel, Addison, Daniel, Addo, Isaac Yeboah, Adegboye, Oyelola A, Adesina, Miracle Ayomikun, Adnan, Mohammad, Adnani, Qorinah Estiningtyas Sakilah, Advani, Shailesh M, Afrin, Sumia, Afzal, Muhammad Sohail, Aggarwal, Manik, Ahinkorah, Bright Opoku, Ahmad, Araz Ramazan, Ahmad, Rizwan, Ahmad, Sajjad, Ahmad, Sohail, Ahmadi, Sepideh, Ahmed, Haroon, Ahmed, Luai A, Ahmed, Muktar Beshir, Rashid, Tarik Ahmed, Aiman, Wajeeha, Ajami, Marjan, Akalu, Gizachew Taddesse, Akbarzadeh-Khiavi, Mostafa, Aklilu, Addis, Akonde, Maxwell, Akunna, Chisom Joyqueenet, Hamad, Hanadi Al, Alahdab, Fares, Alanezi, Fahad Mashhour, Alanzi, Turki M, Alessy, Saleh Ali, Algammal, Abdelazeem M, Al-Hanawi, Mohammed Khaled, Alhassan, Robert Kaba, Ali, Beriwan Abdulqadir, Ali, Liaqat, Ali, Syed Shujait, Alimohamadi, Yousef, Alipour, Vahid, Aljunid, Syed Mohamed, Alkhayyat, Motasem, Al-Maweri, Sadeq Ali Ali, Almustanyir, Sami, Alonso, Nivaldo, Alqalyoobi, Shehabaldin, Al-Raddadi, Rajaa M, Al-Rifai, Rami H Hani, Al-Sabah, Salman Khalifah, Al-Tammemi, Ala'a B, Altawalah, Haya, Alvis-Guzman, Nelson, Amare, Firehiwot, Ameyaw, Edward Kwabena, Dehkordi, Javad Javad Aminian, Amirzade-Iranaq, Mohammad Hosein, Amu, Hubert, Amusa, Ganiyu Adeniyi, Ancuceanu, Robert, Anderson, Jason A, Animut, Yaregal Animut, Anoushiravani, Amir, Anoushirvani, Ali Arash, Ansari-Moghaddam, Alireza, Ansha, Mustafa Geleto, Antony, Benny, Antwi, Maxwell Hubert, Anwar, Sumadi Lukman, and Anwer, Razique

Subjects
Prevention, Cancer, Aetiology, 2.2 Factors relating to the physical environment, Good Health and Well Being, Female, Global Burden of Disease, Global Health, Humans, Male, Neoplasms, Quality-Adjusted Life Years, Risk Assessment, Risk Factors, Smoking, GBD 2019 Cancer Risk Factors Collaborators, Medical and Health Sciences, General & Internal Medicine
Abstract

BackgroundUnderstanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally.MethodsThe GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk-outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented.FindingsGlobally, in 2019, the risk factors included in this analysis accounted for 4·45 million (95% uncertainty interval 4·01-4·94) deaths and 105 million (95·0-116) DALYs for both sexes combined, representing 44·4% (41·3-48·4) of all cancer deaths and 42·0% (39·1-45·6) of all DALYs. There were 2·88 million (2·60-3·18) risk-attributable cancer deaths in males (50·6% [47·8-54·1] of all male cancer deaths) and 1·58 million (1·36-1·84) risk-attributable cancer deaths in females (36·3% [32·5-41·3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20·4% (12·6-28·4) and DALYs by 16·8% (8·8-25·0), with the greatest percentage increase in metabolic risks (34·7% [27·9-42·8] and 33·3% [25·8-42·0]).InterpretationThe leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden.FundingBill & Melinda Gates Foundation.

Published
2022

14. Comparative review of the guidelines for anterior urethral stricture

Author

Abbasi, Behzad, Shaw, Nathan M, Lui, Jason L, Li, Kevin D, Low, Patrick, Hakam, Nizar, Nabavizadeh, Behnam, and Breyer, Benjamin N

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Urologic Diseases, Clinical Research, Endoscopy, Female, Humans, Male, Plastic Surgery Procedures, Treatment Outcome, Urethra, Urethral Stricture, Urologic Surgical Procedures, Male, Urology, Guidelines, Urethroplasty, Anterior, Reconstructive Surgery, Urology & Nephrology, Clinical sciences
Abstract

PurposeWe aimed to provide a detailed comparison between the American Urologic Association (AUA), Société Internationale d'Urologie (SIU), and the European Association of Urology (EAU) guidelines on the evaluation, management, and follow-up of the patients with anterior urethral stricture disease (USD).MethodsThe urethral stricture guidelines from SUI, AUA, and EAU were collected and evaluated regarding the recommendations on diagnosis, evaluation, and treatment of anterior USD. The strength of evidence for each statement was included and discussed when guidelines differed.ResultsWhile the guidelines remarkably align in terms of the diagnostic workup and follow-up, there is discordance in the management of anterior urethral strictures, specifically for the use of endoscopic treatment and stenting. Further, the EAU offers more comprehensive recommendations regarding urethroplasty techniques and patient follow-up. The EAU guidelines are the most recent and first to offer guidance for USD in transgender people and women.ConclusionReconstructive urology is a rapidly adapting field, and best practices change accordingly. Guideline statements have become more inclusive and expansive but will require further research to improve the level of evidence and continue to provide patients and providers with the best treatment plans.

Published
2022

15. Incidence of venous thromboembolism in benign urologic reconstructive cases

Author

Shaw, Nathan M, Hakam, Nizar, Lui, Jason L, Nabavizadeh, Behnam, Li, Kevin D, Low, Patrick, Abbasi, Behzad, and Breyer, Benjamin N

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Clinical Research, Hematology, Adolescent, Aged, Female, Humans, Incidence, Male, Operative Time, Postoperative Complications, Plastic Surgery Procedures, Risk Factors, Venous Thromboembolism, Venous thromboembolism, Deep vein thrombosis, Pulmonary embolism, Reconstructive urology, ACS-NSQIP, Urology & Nephrology, Clinical sciences
Abstract

PurposeTo evaluate the rate of perioperative venous thromboembolism (VTE) among patients undergoing common benign urologic reconstructive cases. We hypothesize that this rate will be lower than previously described.MethodsWe utilized the American College of Surgeons National Surgical Quality Improvement Project database from 2015 to 2019 to evaluate 30-day perioperative risk of VTE. Patients ≥ 18 years old undergoing benign urologic reconstructive cases were selected using Current Procedural Terminology (CPT) codes. Demographic, comorbidity, and operative variables were captured. The primary outcome was VTE within the 30-day postoperative period.ResultsWe identified 8467 patients who met inclusion criteria. The majority of patients were male (> 95%) with an average age of 65 and BMI of 29.6. There were 23 VTE events (0.27%) within the 30-day perioperative period. Fourteen (14/59) procedures had a perioperative VTE. Many of the traditional factors for VTE including operative time and obesity significantly increased risk of VTE in univariate analysis. In multivariate analysis, only BMI (OR 1.09; 95% CI 1.01-1.12) and inpatient status (OR 4.42; 95% CI 1.9-10.2) were correlated with increased perioperative VTE.ConclusionThe rate of VTE among patients undergoing benign urologic reconstructive cases is low. Providers should continue to have high index of suspicion particularly for inpatients with high BMI in addition to other known risk factors for VTE.

Published
2022

16. Multidisciplinary management in Fournier's gangrene

Author

Koch, George E., Abbasi, Behzad, Agoubi, Lauren, Breyer, Benjamin N., Clark, Nina, Dick, Brian P., Friedrich, Jeffrey B., Hampson, Lindsay A., Hernandez, Alexandra, Maine, Rebecca, Osterberg, E. Charles, Teal, Lindsey, Woodle, Capt. Tarah, and Hagedorn, Judith C.

Published
2024
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18. The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019

Author

Collaborators, GBD 2019 Adolescent Young Adult Cancer, Alvarez, Elysia M, Force, Lisa M, Xu, Rixing, Compton, Kelly, Lu, Dan, Henrikson, Hannah Jacqueline, Kocarnik, Jonathan M, Harvey, James D, Pennini, Alyssa, Dean, Frances E, Fu, Weijia, Vargas, Martina T, Keegan, Theresa HM, Ariffin, Hany, Barr, Ronald D, Erdomaeva, Yana Arturovna, Gunasekera, D Sanjeeva, John-Akinola, Yetunde O, Ketterl, Tyler G, Kutluk, Tezer, Malogolowkin, Marcio Henrique, Mathur, Prashant, Radhakrishnan, Venkatraman, Ries, Lynn Ann Gloeckler, Rodriguez-Galindo, Carlos, Sagoyan, Garik Barisovich, Sultan, Iyad, Abbasi, Behzad, Abbasi-Kangevari, Mohsen, Abbasi-Kangevari, Zeinab, Abbastabar, Hedayat, Abdelmasseh, Michael, Abd-Elsalam, Sherief, Abdoli, Amir, Abebe, Haimanot, Abedi, Aidin, Abidi, Hassan, Abolhassani, Hassan, Ali, Hiwa Abubaker, Abu-Gharbieh, Eman, Achappa, Basavaprabhu, Acuna, Juan Manuel, Adedeji, Isaac Akinkunmi, Adegboye, Oyelola A, Adnani, Qorinah Estiningtyas Sakilah, Advani, Shailesh M, Afzal, Muhammad Sohail, Meybodi, Mohamad Aghaie, Ahadinezhad, Bahman, Ahinkorah, Bright Opoku, Ahmad, Sajjad, Ahmadi, Sepideh, Ahmed, Muktar Beshir, Rashid, Tarik Ahmed, Salih, Yusra Ahmed, Aiman, Wajeeha, Akalu, Gizachew Taddesse, Al Hamad, Hanadi, Alahdab, Fares, AlAmodi, Abdulhadi A, Alanezi, Fahad Mashhour, Alanzi, Turki M, Alem, Adugnaw Zeleke, Alem, Dejene Tsegaye, Alemayehu, Yosef, Alhalaiqa, Fadwa Naji, Alhassan, Robert Kaba, Ali, Saqib, Alicandro, Gianfranco, Alipour, Vahid, Aljunid, Syed Mohamed, Alkhayyat, Motasem, Alluri, Sunitha, Almasri, Nihad A, Al-Maweri, Sadeq Ali, Almustanyir, Sami, Al-Raddadi, Rajaa M, Alvis-Guzman, Nelson, Ameyaw, Edward Kwabena, Amini, Saeed, Amu, Hubert, Ancuceanu, Robert, Andrei, Catalina Liliana, Andrei, Tudorel, Ansari, Fereshteh, Ansari-Moghaddam, Alireza, Anvari, Davood, Anyasodor, Anayochukwu Edward, Arabloo, Jalal, Arab-Zozani, Morteza, Argaw, Ayele Mamo, Arshad, Muhammad, Arulappan, Judie, Aryannejad, Armin, Asemi, Zatollah, Jafarabadi, Mohammad Asghari, Atashzar, Mohammad Reza, Atorkey, and Atreya, Alok

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Burden of Illness, Prevention, Pediatric, Rare Diseases, Cancer, 2.4 Surveillance and distribution, Good Health and Well Being, Adolescent, Adult, Cause of Death, Disability-Adjusted Life Years, Female, Global Burden of Disease, Global Health, Humans, Incidence, Life Expectancy, Male, Mortality, Neoplasms, Prevalence, Risk Factors, Socioeconomic Factors, Young Adult, GBD 2019 Adolescent Young Adult Cancer Collaborators, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

BackgroundIn estimating the global burden of cancer, adolescents and young adults with cancer are often overlooked, despite being a distinct subgroup with unique epidemiology, clinical care needs, and societal impact. Comprehensive estimates of the global cancer burden in adolescents and young adults (aged 15-39 years) are lacking. To address this gap, we analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, with a focus on the outcome of disability-adjusted life-years (DALYs), to inform global cancer control measures in adolescents and young adults.MethodsUsing the GBD 2019 methodology, international mortality data were collected from vital registration systems, verbal autopsies, and population-based cancer registry inputs modelled with mortality-to-incidence ratios (MIRs). Incidence was computed with mortality estimates and corresponding MIRs. Prevalence estimates were calculated using modelled survival and multiplied by disability weights to obtain years lived with disability (YLDs). Years of life lost (YLLs) were calculated as age-specific cancer deaths multiplied by the standard life expectancy at the age of death. The main outcome was DALYs (the sum of YLLs and YLDs). Estimates were presented globally and by Socio-demographic Index (SDI) quintiles (countries ranked and divided into five equal SDI groups), and all estimates were presented with corresponding 95% uncertainty intervals (UIs). For this analysis, we used the age range of 15-39 years to define adolescents and young adults.FindingsThere were 1·19 million (95% UI 1·11-1·28) incident cancer cases and 396 000 (370 000-425 000) deaths due to cancer among people aged 15-39 years worldwide in 2019. The highest age-standardised incidence rates occurred in high SDI (59·6 [54·5-65·7] per 100 000 person-years) and high-middle SDI countries (53·2 [48·8-57·9] per 100 000 person-years), while the highest age-standardised mortality rates were in low-middle SDI (14·2 [12·9-15·6] per 100 000 person-years) and middle SDI (13·6 [12·6-14·8] per 100 000 person-years) countries. In 2019, adolescent and young adult cancers contributed 23·5 million (21·9-25·2) DALYs to the global burden of disease, of which 2·7% (1·9-3·6) came from YLDs and 97·3% (96·4-98·1) from YLLs. Cancer was the fourth leading cause of death and tenth leading cause of DALYs in adolescents and young adults globally.InterpretationAdolescent and young adult cancers contributed substantially to the overall adolescent and young adult disease burden globally in 2019. These results provide new insights into the distribution and magnitude of the adolescent and young adult cancer burden around the world. With notable differences observed across SDI settings, these estimates can inform global and country-level cancer control efforts.FundingBill & Melinda Gates Foundation, American Lebanese Syrian Associated Charities, St Baldrick's Foundation, and the National Cancer Institute.

Published
2022

21. Multidisciplinary Management in Fournier's Gangrene

Author

Abbasi, Behzad, primary, Agoubi, Lauren, additional, Breyer, Benjamin N., additional, Clark, Nina, additional, Dick, Brian P., additional, Friedrich, Jeffrey B., additional, Hagedorn, Judith C., additional, Hampson, Lindsay A., additional, Hernandez, Alexandra, additional, Koch, George E., additional, Maine, Rebecca, additional, Osterberg, E. Charles, additional, Teal, Lindsey, additional, and Woodle, Capt. Tarah, additional

Published
2024
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24. In Brief

Author

Abbasi, Behzad, primary, Agoubi, Lauren, additional, Breyer, Benjamin N., additional, Clark, Nina, additional, Dick, Brian P., additional, Friedrich, Jeffrey B., additional, Hagedorn, Judith C., additional, Hampson, Lindsay A., additional, Hernandez, Alexandra, additional, Koch, George E., additional, Maine, Rebecca, additional, Osterberg, E. Charles, additional, Teal, Lindsey, additional, and Woodle, Tarah, additional

Published
2024
Full Text
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26. The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019

Author

Tran, Khanh Bao, Lang, Justin J, Compton, Kelly, Xu, Rixing, Acheson, Alistair R, Henrikson, Hannah Jacqueline, Kocarnik, Jonathan M, Penberthy, Louise, Aali, Amirali, Abbas, Qamar, Abbasi, Behzad, Abbasi-Kangevari, Mohsen, Abbasi-Kangevari, Zeinab, Abbastabar, Hedayat, Abdelmasseh, Michael, Abd-Elsalam, Sherief, Abdelwahab, Ahmed Abdelwahab, Abdoli, Gholamreza, Abdulkadir, Hanan Abdulkadir, Abedi, Aidin, Abegaz, Kedir Hussein, Abidi, Hassan, Aboagye, Richard Gyan, Abolhassani, Hassan, Absalan, Abdorrahim, Abtew, Yonas Derso, Abubaker Ali, Hiwa, Abu-Gharbieh, Eman, Achappa, Basavaprabhu, Acuna, Juan Manuel, Addison, Daniel, Addo, Isaac Yeboah, Adegboye, Oyelola A, Adesina, Miracle Ayomikun, Adnan, Mohammad, Adnani, Qorinah Estiningtyas Sakilah, Advani, Shailesh M, Afrin, Sumia, Afzal, Muhammad Sohail, Aggarwal, Manik, Ahinkorah, Bright Opoku, Ahmad, Araz Ramazan, Ahmad, Rizwan, Ahmad, Sajjad, Ahmad, Sohail, Ahmadi, Sepideh, Ahmed, Haroon, Ahmed, Luai A, Ahmed, Muktar Beshir, Ahmed Rashid, Tarik, Aiman, Wajeeha, Ajami, Marjan, Akalu, Gizachew Taddesse, Akbarzadeh-Khiavi, Mostafa, Aklilu, Addis, Akonde, Maxwell, Akunna, Chisom Joyqueenet, Al Hamad, Hanadi, Alahdab, Fares, Alanezi, Fahad Mashhour, Alanzi, Turki M, Alessy, Saleh Ali, Algammal, Abdelazeem M, Al-Hanawi, Mohammed Khaled, Alhassan, Robert Kaba, Ali, Beriwan Abdulqadir, Ali, Liaqat, Ali, Syed Shujait, Alimohamadi, Yousef, Alipour, Vahid, Aljunid, Syed Mohamed, Alkhayyat, Motasem, Al-Maweri, Sadeq Ali Ali, Almustanyir, Sami, Alonso, Nivaldo, Alqalyoobi, Shehabaldin, Al-Raddadi, Rajaa M, Al-Rifai, Rami H Hani, Al-Sabah, Salman Khalifah, Al-Tammemi, Ala'a B, Altawalah, Haya, Alvis-Guzman, Nelson, Amare, Firehiwot, Ameyaw, Edward Kwabena, Aminian Dehkordi, Javad Javad, Amirzade-Iranaq, Mohammad Hosein, Amu, Hubert, Amusa, Ganiyu Adeniyi, Ancuceanu, Robert, Anderson, Jason A, Animut, Yaregal Animut, Anoushiravani, Amir, Anoushirvani, Ali Arash, Ansari-Moghaddam, Alireza, Ansha, Mustafa Geleto, Antony, Benny, Antwi, Maxwell Hubert, Anwar, Sumadi Lukman, Anwer, Razique, Anyasodor, Anayochukwu Edward, Arabloo, Jalal, Arab-Zozani, Morteza, Aremu, Olatunde, Argaw, Ayele Mamo, Ariffin, Hany, Aripov, Timur, Arshad, Muhammad, Artaman, Al, Arulappan, Judie, Aruleba, Raphael Taiwo, Aryannejad, Armin, Asaad, Malke, Asemahagn, Mulusew A, Asemi, Zatollah, Asghari-Jafarabadi, Mohammad, Ashraf, Tahira, Assadi, Reza, Athar, Mohammad, Athari, Seyyed Shamsadin, Atout, Maha Moh'd Wahbi, Attia, Sameh, Aujayeb, Avinash, Ausloos, Marcel, Avila-Burgos, Leticia, Awedew, Atalel Fentahun, Awoke, Mamaru Ayenew, Awoke, Tewachew, Ayala Quintanilla, Beatriz Paulina, Ayana, Tegegn Mulatu, Ayen, Solomon Shitu, Azadi, Davood, Azadnajafabad, Sina, Azami-Aghdash, Saber, Azanaw, Melkalem Mamuye, Azangou-Khyavy, Mohammadreza, Azari Jafari, Amirhossein, Azizi, Hosein, Azzam, Ahmed Y Y, Babajani, Amirhesam, Badar, Muhammad, Badiye, Ashish D, Baghcheghi, Nayereh, Bagheri, Nader, Bagherieh, Sara, Bahadory, Saeed, Baig, Atif Amin, Baker, Jennifer L, Bakhtiari, Ahad, Bakshi, Ravleen Kaur, Banach, Maciej, Banerjee, Indrajit, Bardhan, Mainak, Barone-Adesi, Francesco, Barra, Fabio, Barrow, Amadou, Bashir, Nasir Z, Bashiri, Azadeh, Basu, Saurav, Batiha, Abdul-Monim Mohammad, Begum, Aeysha, Bekele, Alehegn Bekele, Belay, Alemayehu Sayih, Belete, Melaku Ashagrie, Belgaumi, Uzma Iqbal, Bell, Arielle Wilder, Belo, Luis, Benzian, Habib, Berhie, Alemshet Yirga, Bermudez, Amiel Nazer C, Bernabe, Eduardo, Bhagavathula, Akshaya Srikanth, Bhala, Neeraj, Bhandari, Bharti Bhandari, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhattacharyya, Krittika, Bhojaraja, Vijayalakshmi S, Bhuyan, Soumitra S, Bibi, Sadia, Bilchut, Awraris Hailu, Bintoro, Bagas Suryo, Biondi, Antonio, Birega, Mesfin Geremaw Birega, Birhan, Habitu Eshetu, Bjørge, Tone, Blyuss, Oleg, Bodicha, Belay Boda Abule, Bolla, Srinivasa Rao, Boloor, Archith, Bosetti, Cristina, Braithwaite, Dejana, Brauer, Michael, Brenner, Hermann, Briko, Andrey Nikolaevich, Briko, Nikolay Ivanovich, Buchanan, Christina Maree, Bulamu, Norma B, Bustamante-Teixeira, Maria Teresa, Butt, Muhammad Hammad, Butt, Nadeem Shafique, Butt, Zahid A, Caetano dos Santos, Florentino Luciano, Cámera, Luis Alberto, Cao, Chao, Cao, Yin, Carreras, Giulia, Carvalho, Márcia, Cembranel, Francieli, Cerin, Ester, Chakraborty, Promit Ananyo, Charalampous, Periklis, Chattu, Vijay Kumar, Chimed-Ochir, Odgerel, Chirinos-Caceres, Jesus Lorenzo, Cho, Daniel Youngwhan, Cho, William C S, Christopher, Devasahayam J, Chu, Dinh-Toi, Chukwu, Isaac Sunday, Cohen, Aaron J, Conde, Joao, Cortés, Sandra, Costa, Vera Marisa, Cruz-Martins, Natália, Culbreth, Garland T, Dadras, Omid, Dagnaw, Fentaw Teshome, Dahlawi, Saad M A, Dai, Xiaochen, Dandona, Lalit, Dandona, Rakhi, Daneshpajouhnejad, Parnaz, Danielewicz, Anna, Dao, An Thi Minh, Darvishi Cheshmeh Soltani, Reza, Darwesh, Aso Mohammad, Das, Saswati, Davitoiu, Dragos Virgil, Davtalab Esmaeili, Elham, De la Hoz, Fernando Pio, Debela, Sisay Abebe, Dehghan, 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Ghafourifard, Mansour, Ghamari, Seyyed-Hadi, Ghasemi Nour, Mohammad, Ghassemi, Fariba, Ghimire, Ajnish, Ghith, Nermin, Gholamalizadeh, Maryam, Gholizadeh Navashenaq, Jamshid, Ghozy, Sherief, Gilani, Syed Amir, Gill, Paramjit Singh, Ginindza, Themba G, Gizaw, Abraham Tamirat T, Glasbey, James C, Godos, Justyna, Goel, Amit, Golechha, Mahaveer, Goleij, Pouya, Golinelli, Davide, Golitaleb, Mohamad, Gorini, Giuseppe, Goulart, Bárbara Niegia Garcia, Grosso, Giuseppe, Guadie, Habtamu Alganeh, Gubari, Mohammed Ibrahim Mohialdeen, Gudayu, Temesgen Worku, Guerra, Maximiliano Ribeiro, Gunawardane, Damitha Asanga, Gupta, Bhawna, Gupta, Sapna, Gupta, Veer Bala, Gupta, Vivek Kumar, Gurara, Mekdes Kondale, Guta, Alemu, Habibzadeh, Parham, Haddadi Avval, Atlas, Hafezi-Nejad, Nima, Hajj Ali, Adel, Haj-Mirzaian, Arvin, Halboub, Esam S, Halimi, Aram, Halwani, Rabih, Hamadeh, Randah R, Hameed, Sajid, Hamidi, Samer, Hanif, Asif, Hariri, Sanam, Harlianto, Netanja I, Haro, Josep Maria, Hartono, Risky Kusuma, 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Moradi, Abdolvahab, Moradi, Yousef, Moradi Sarabi, Mostafa, Moraga, Paula, Morawska, Lidia, Morrison, Shane Douglas, Morze, Jakub, Mosapour, Abbas, Mostafavi, Ebrahim, Mousavi, Seyyed Meysam, Mousavi Isfahani, Haleh, Mousavi Khaneghah, Amin, Mpundu-Kaambwa, Christine, Mubarik, Sumaira, Mulita, Francesk, Munblit, Daniel, Munro, Sandra B, Murillo-Zamora, Efrén, Musa, Jonah, Nabhan, Ashraf F, Nagarajan, Ahamarshan Jayaraman, Nagaraju, Shankar Prasad, Nagel, Gabriele, Naghipour, Mohammadreza, Naimzada, Mukhammad David, Nair, Tapas Sadasivan, Naqvi, Atta Abbas, Narasimha Swamy, Sreenivas, Narayana, Aparna Ichalangod, Nassereldine, Hasan, Natto, Zuhair S, Nayak, Biswa Prakash, Ndejjo, Rawlance, Nduaguba, Sabina Onyinye, Negash, Wogene Wogene, Nejadghaderi, Seyed Aria, Nejati, Kazem, Neupane Kandel, Sandhya, Nguyen, Huy Van Nguyen, Niazi, Robina Khan, Noor, Nurulamin M, Noori, Maryam, Noroozi, Nafise, Nouraei, Hasti, Nowroozi, Ali, Nuñez-Samudio, Virginia, Nzoputam, Chimezie Igwegbe, Nzoputam, Ogochukwu Janet, Oancea, Bogdan, Odukoya, Oluwakemi Ololade, Oghenetega, Onome Bright, Ogunsakin, Ropo Ebenezer, Oguntade, Ayodipupo Sikiru, Oh, In-Hwan, Okati-Aliabad, Hassan, Okekunle, Akinkunmi Paul, Olagunju, Andrew T, Olagunju, Tinuke O, Olakunde, Babayemi Oluwaseun, Olufadewa, Isaac Iyinoluwa, Omer, Emad, Omonisi, Abidemi E Emmanuel, Ong, Sokking, Onwujekwe, Obinna E, Orru, Hans, Otstavnov, Stanislav S, Oulhaj, Abderrahim, Oumer, Bilcha, Owopetu, Oluwatomi Funbi, Oyinloye, Babatunji Emmanuel, P A, Mahesh, Padron-Monedero, Alicia, Padubidri, Jagadish Rao, Pakbin, Babak, Pakshir, Keyvan, Pakzad, Reza, Palicz, Tamás, Pana, Adrian, Pandey, Anamika, Pandey, Ashok, Pant, Suman, Pardhan, Shahina, Park, Eun-Cheol, Park, Eun-Kee, Park, Seoyeon, Patel, Jay, Pati, Siddhartha, Paudel, Rajan, Paudel, Uttam, Paun, Mihaela, Pazoki Toroudi, Hamidreza, Peng, Minjin, Pereira, Jeevan, Pereira, Renato B, Perna, Simone, Perumalsamy, Navaraj, Pestell, Richard G, Pezzani, Raffaele, Piccinelli, Cristiano, Pillay, Julian David, Piracha, Zahra Zahid, Pischon, Tobias, Postma, Maarten J, Pourabhari Langroudi, Ashkan, Pourshams, Akram, Pourtaheri, Naeimeh, Prashant, Akila, Qadir, Mirza Muhammad Fahd, Quazi Syed, Zahiruddin, Rabiee, Mohammad, Rabiee, Navid, Radfar, Amir, Radhakrishnan, Raghu Anekal, Radhakrishnan, Venkatraman, Raeisi, Mojtaba, Rafiee, Ata, Rafiei, Alireza, Raheem, Nasiru, Rahim, Fakher, Rahman, Md Obaidur, Rahman, Mosiur, Rahman, Muhammad Aziz, Rahmani, Amir Masoud, Rahmani, Shayan, Rahmanian, Vahid, Rajai, Nazanin, Rajesh, Aashish, Ram, Pradhum, Ramezanzadeh, Kiana, Rana, Juwel, Ranabhat, Kamal, Ranasinghe, Priyanga, Rao, Chythra R, Rao, Sowmya J, Rashedi, Sina, Rashidi, Amirfarzan, Rashidi, Mahsa, Rashidi, Mohammad-Mahdi, Ratan, Zubair Ahmed, Rawaf, David Laith, Rawaf, Salman, Rawal, Lal, Rawassizadeh, Reza, Razeghinia, Mohammad Sadegh, Rehman, Ashfaq Ur, Rehman, Inayat ur, Reitsma, Marissa B, Renzaho, Andre M N, Rezaei, Maryam, Rezaei, Nazila, Rezaei, Negar, Rezaei, Nima, Rezaei, Saeid, Rezaeian, Mohsen, Rezapour, Aziz, Riad, Abanoub, Rikhtegar, Reza, Rios-Blancas, Maria, Roberts, Thomas J, Rohloff, Peter, Romero-Rodríguez, Esperanza, Roshandel, Gholamreza, Rwegerera, Godfrey M, S, Manjula, Saber-Ayad, Maha Mohamed, Saberzadeh-Ardestani, Bahar, Sabour, Siamak, Saddik, Basema, Sadeghi, Erfan, Saeb, Mohammad Reza, Saeed, Umar, Safaei, Mohsen, Safary, Azam, Sahebazzamani, Maryam, Sahebkar, Amirhossein, Sahoo, Harihar, Sajid, Mirza Rizwan, Salari, Hedayat, Salehi, Sana, Salem, Marwa Rashad, Salimzadeh, Hamideh, Samodra, Yoseph Leonardo, Samy, Abdallah M, Sanabria, Juan, Sankararaman, Senthilkumar, Sanmarchi, Francesco, Santric-Milicevic, Milena M, Saqib, Muhammad Arif Nadeem, Sarveazad, Arash, Sarvi, Fatemeh, Sathian, Brijesh, Satpathy, Maheswar, Sayegh, Nicolas, Schneider, Ione Jayce Ceola, Schwarzinger, Michaël, Šekerija, Mario, Senthilkumaran, Subramanian, Sepanlou, Sadaf G, Seylani, Allen, Seyoum, Kenbon, Sha, Feng, Shafaat, Omid, Shah, Pritik A, Shahabi, Saeed, Shahid, Izza, Shahrbaf, Mohammad Amin, Shahsavari, Hamid R, Shaikh, Masood Ali, Shaka, Mohammed Feyisso, Shaker, Elaheh, Shannawaz, Mohammed, Sharew, Mequannent Melaku Sharew, Sharifi, Azam, Sharifi-Rad, Javad, Sharma, Purva, Shashamo, Bereket Beyene, Sheikh, Aziz, Sheikh, Mahdi, Sheikhbahaei, Sara, Sheikhi, Rahim Ali, Sheikhy, Ali, Shepherd, Peter Robin, Shetty, Adithi, Shetty, Jeevan K, Shetty, Ranjitha S, Shibuya, Kenji, Shirkoohi, Reza, Shirzad-Aski, Hesamaddin, Shivakumar, K M, Shivalli, Siddharudha, Shivarov, Velizar, Shobeiri, Parnian, Shokri Varniab, Zahra, Shorofi, Seyed Afshin, Shrestha, Sunil, Sibhat, Migbar Mekonnen, Siddappa Malleshappa, Sudeep K, Sidemo, Negussie Boti, Silva, Diego Augusto Santos, Silva, Luís Manuel Lopes Rodrigues, Silva Julian, Guilherme, Silvestris, Nicola, Simegn, Wudneh, Singh, Achintya Dinesh, Singh, Ambrish, Singh, Garima, Singh, Harpreet, Singh, Jasvinder A, Singh, Jitendra Kumar, Singh, Paramdeep, Singh, Surjit, Sinha, Dhirendra Narain, Sinke, Abiy H, Siraj, Md Shahjahan, Sitas, Freddy, Siwal, Samarjeet Singh, Skryabin, Valentin Yurievich, Skryabina, Anna Aleksandrovna, Socea, Bogdan, Soeberg, Matthew J, Sofi-Mahmudi, Ahmad, Solomon, Yonatan, Soltani-Zangbar, Mohammad Sadegh, Song, Suhang, Song, Yimeng, Sorensen, Reed J D, Soshnikov, Sergey, Sotoudeh, Houman, Sowe, Alieu, Sufiyan, Mu'awiyyah Babale, Suk, Ryan, Suleman, Muhammad, Suliankatchi Abdulkader, Rizwan, Sultana, Saima, Sur, Daniel, Szócska, Miklós, Tabaeian, Seidamir Pasha, Tabarés-Seisdedos, Rafael, Tabatabaei, Seyyed Mohammad, Tabuchi, Takahiro, Tadbiri, Hooman, Taheri, Ensiyeh, Taheri, Majid, Taheri Soodejani, Moslem, Takahashi, Ken, Talaat, Iman M, Tampa, Mircea, Tan, Ker-Kan, Tat, Nathan Y, Tat, Vivian Y, Tavakoli, Ahmad, Tavakoli, Arash, Tehrani-Banihashemi, Arash, Tekalegn, Yohannes, Tesfay, Fisaha Haile, Thapar, Rekha, Thavamani, Aravind, Thoguluva Chandrasekar, Viveksandeep, Thomas, Nihal, Thomas, Nikhil Kenny, Ticoalu, Jansje Henny Vera, Tiyuri, Amir, Tollosa, Daniel Nigusse, Topor-Madry, Roman, Touvier, Mathilde, Tovani-Palone, Marcos Roberto, Traini, Eugenio, Tran, Mai Thi Ngoc, Tripathy, Jaya Prasad, Ukke, Gebresilasea Gendisha, Ullah, Irfan, Ullah, Saif, Ullah, Sana, Unnikrishnan, Bhaskaran, Vacante, Marco, Vaezi, Maryam, Valadan Tahbaz, Sahel, Valdez, Pascual R, Vardavas, Constantine, Varthya, Shoban Babu, Vaziri, Siavash, Velazquez, Diana Zuleika, Veroux, Massimiliano, Villeneuve, Paul J, Violante, Francesco S, Vladimirov, Sergey Konstantinovitch, Vlassov, Vasily, Vo, Bay, Vu, Linh Gia, Wadood, Abdul Wadood, Waheed, Yasir, Walde, Mandaras Tariku, Wamai, Richard G, Wang, Cong, Wang, Fang, Wang, Ning, Wang, Yu, Ward, Paul, Waris, Abdul, Westerman, Ronny, Wickramasinghe, Nuwan Darshana, Woldemariam, Melat, Woldu, Berhanu, Xiao, Hong, Xu, Suowen, Xu, Xiaoyue, Yadav, Lalit, Yahyazadeh Jabbari, Seyed Hossein, Yang, Lin, Yazdanpanah, Fereshteh, Yeshaw, Yigizie, Yismaw, Yazachew, Yonemoto, Naohiro, Younis, Mustafa Z, Yousefi, Zabihollah, Yousefian, Fatemeh, Yu, Chuanhua, Yu, Yong, Yunusa, Ismaeel, Zahir, Mazyar, Zaki, Nazar, Zaman, Burhan Abdullah, Zangiabadian, Moein, Zare, Fariba, Zare, Iman, Zareshahrabadi, Zahra, Zarrintan, Armin, Zastrozhin, Mikhail Sergeevich, Zeineddine, Mohammad A, Zhang, Dongyu, Zhang, Jianrong, Zhang, Yunquan, Zhang, Zhi-Jiang, Zhou, Linghui, Zodpey, Sanjay, Zoladl, Mohammad, Vos, Theo, Hay, Simon I, Force, Lisa M, and Murray, Christopher J L

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2022
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27. Health system performance in Iran: a systematic analysis for the Global Burden of Disease Study 2019

Author

Farzadfar, Farshad, Naghavi, Mohsen, Sepanlou, Sadaf G, Saeedi Moghaddam, Sahar, Dangel, William James, Davis Weaver, Nicole, Aminorroaya, Arya, Azadnajafabad, Sina, Koolaji, Sogol, Mohammadi, Esmaeil, Rezaei, Negar, Abbas, Jaffar, Abbasi, Behzad, Abbasifard, Mitra, Abbasi-Kangevari, Mohsen, Abbasi-Kangevari, Zeinab, Abbastabar, Hedayat, Abdoli, Amir, Abdollahi, Mohammad, Abdollahzade, Sina, Abolhassani, Hassan, Abrehdari-Tafreshi, Zahra, Aghababaei, Soodabeh, Ahadinezhad, Bahman, Ahmadi, Ali, Ahmadi, Sepideh, Ahmadieh, Hamid, Akbari, Mohammad Esmaeil, Alimohamadi, Yousef, Alipour, Vahid, Alizade, Hesam, Alvand, Saba, Amini, Saeed, Amiri, Sohrab, Anoushirvani, Ali Arash, Ansari, Fereshteh, Arabloo, Jalal, Arab-Zozani, Morteza, Aryan, Zahra, Aryannejad, Armin, Asadi-Aliabadi, Mehran, Asadi-Pooya, Ali A, Asemi, Zatollah, Asgari, Samaneh, Asgary, Saeed, Asghari, Babak, Asghari Jafarabadi, Mohammad, Ashrafi, Elham, Atafar, Zahra, Athari, Seyyed Shamsadin, Avan, Abolfazl, Azadmehr, Abbas, Azami, Hiva, Azangou-Khyavy, Mohammadreza, Azari, Samad, Azari Jafari, Amirhossein, Azarian, Ghasem, Badirzadeh, Alireza, Bahrami, Elham, Bahrami, Mohammad Amin, Barati, Nastaran, Bayati, Mohsen, Bazmandegan, Gholamreza, Behzadifar, Masoud, Bijani, Ali, Bohlouli, Somayeh, Borzouei, Shiva, Daneshpajouhnejad, Parnaz, Dargahi, Abdollah, Daryani, Ahmad, Davoodi Lahijan, Jalal, Didehdar, Mojtaba, Djalalinia, Shirin, Doaei, Saeid, Dorostkar, Fariba, Doshmangir, Leila, Edraki, Mohammadreza, Emami, Amir, Eshrati, Babak, Eskandarieh, Sharareh, Esmaeilzadeh, Firooz, Faghani, Shahriar, Fakhar, Mahdi, Farpour, Hamid Reza, Farrokhpour, Hossein, Fasihi Harandi, Majid, Fereidouni, Mohammad, Foroutan, Masoud, Ghafourifard, Mansour, Ghamari, Azin, Ghamari, Seyyed-Hadi, Ghashghaee, Ahmad, Ghassemi, Fariba, Gholami, Ali, Gholamian, Asadollah, Gholizadeh, Abdolmajid, Goharinezhad, Salime, Goleij, Pouya, Hadei, Mostafa, Hafezi-Nejad, Nima, Hariri, Sanam, Hasanpoor, Edris, Hassanian-Moghaddam, Hossein, Hassanipour, Soheil, Hassankhani, Hadi, Heidari, Mohammad, Heidari-Soureshjani, Reza, Hoseini, Mohammad, Hosseini, Mohammad-Salar, Hosseini, Mostafa, Hosseini, Seyed Kianoosh, Hosseinzadeh, Ali, Hosseinzadeh, Mehdi, Hoveidamanesh, Soodabeh, Iranpour, Pooya, Irvani, Seyed Sina Naghibi, Jaafari, Jalil, Jabbarinejad, Roxana, Jafarinia, Morteza, Jafari-Vayghan, Hamed, Jahani, Mohammad Ali, Jahanmehr, Nader, Jalili, Mahsa, Janghorban, Roksana, Javanmardi, Fatemeh, Joukar, Farahnaz, Kabir, Ali, Kalankesh, Leila R, Kalhor, Rohollah, Kamiab, Zahra, Kamyari, Naser, Karami Matin, Behzad, Karimi, Amirali, Karimi, Salah Eddin, Kazemi Karyani, Ali, Keikavoosi-Arani, Leila, Keramati, Maryam, Keshavarz, Pedram, Keykhaei, Mohammad, Khaleghi, Ali, Khammarnia, Mohammad, Khanali, Javad, Khayamzadeh, Maryam, Khosravi, Sajad, Khosravifar, Mina, Khosravizadeh, Omid, Kianipour, Neda, Kolahi, Ali-Asghar, Maali, Amirhosein, Mahdavi, Mokhtar Mahdavi, Maleki, Afshin, Malekpour, Mohammad-Reza, Mansori, Kamyar, Mansouri, Borhan, Mansournia, Mohammad Ali, Maracy, Mohammad Reza, Marjani, Abdoljalal, Masoudi, Sahar, Masoumi, Seyedeh Zahra, Masoumi-Asl, Hossein, Mayeli, Mahsa, Mehrabi Nasab, Entezar, Mehri, Fereshteh, Miri, Mohammad, Mirmoeeni, Seyyedmohammadsadeq, Mirzaei, Hamed, Mirzaei, Maryam, Mirzaei, Roya, Mohamadkhani, Ashraf, Mohammadi, Heidar, Mohammadi, Seyyede Momeneh, Mohammadi, Shadieh, Mohammadian-Hafshejani, Abdollah, Mohammadifard, Noushin, Mohammadpourhodki, Reza, Mohseni, Mohammad, Mokari, Amin, Momtazmanesh, Sara, Moradi, Abdolvahab, Moradi, Masoud, Moradi, Yousef, Moradi-Joo, Mohammad, Moradpour, Farhad, Moradzadeh, Maliheh, Moradzadeh, Rahmatollah, Mosapour, Abbas, Moslehi, Shandiz, Mouodi, Simin, Naderi, Mehdi, Naderifar, Homa, Najafpour, Zhila, Nazari, Javad, Nejadghaderi, Seyed Aria, Nemati-Anaraki, Leila, Nikpoor, Amin Reza, Nojomi, Marzieh, Noori, Maryam, Nouraei, Hasti, Nowroozi, Ali, Oladnabi, Morteza, Pashazadeh Kan, Fatemeh, Pirestani, Majid, Pirsaheb, Meghdad, Pourahmadi, Mohammadreza, Pourchamani, Hadis, Pourjafar, Hadi, Pourshams, Akram, Rabiee, Mohammad, Rabiee, Navid, Rafiei, Alireza, Rafiei, Sima, Rahim, Fakher, Rahmani, Amir Masoud, Rashedi, Sina, Rashedi, Vahid, Rashidi, Amirfarzan, Rashidi, Mahsa, Rashidi, Mohammad-Mahdi, Ravangard, Ramin, Rawassizadeh, Reza, Razeghian-Jahromi, Iman, Razeghinia, Mohammad Sadegh, Redford, Sofia B, Rezaei, Maryam, Rezaei, Nazila, Rezaei, Nima, Rezaei, Saeid, Rezaei Aliabadi, Hossein, Rezaeian, Mohsen, Rezai, Mohammad Sadegh, Rezapour, Aziz, Rezazadeh, Hossein, Rezazadeh-Khadem, Sahba, Rostamian, Morteza, Sadeghi, Ehsan, Sadeghi, Erfan, Sadeghi, Masoumeh, Sadeghian, Reihaneh, Sadeghian, Saeid, Safarpour, Hamid, Safdarian, Mahdi, Safi, Sare, Sahebazzamani, Maryam, Sahebkar, Amirhossein, Sahraian, Mohammad Ali, Salahi, Sarvenaz, Salamati, Payman, Samadi Kafil, Hossein, Sarikhani, Yaser, Sarkhosh, Maryam, Sarveazad, Arash, Seyed-Nezhad, Maryam, Shafaat, Omid, Shaghaghi, Zahra, Shahabi, Saeed, Shahin, Sarvenaz, Shaker, Elaheh, Shakiba, Saeed, Shamsi, MohammadBagher, Shamsoddin, Erfan, Sharafi, Kiomars, Sharifian, Sakineh, Shaygan, Maryam, Sheikhtaheri, Abbas, Shiani, Amir, Shirbandi, Kiarash, Shirkoohi, Reza, Shobeiri, Parnian, Shokri, Azad, Siabani, Soraya, Sima, Ali Reza, Sofi-Mahmudi, Ahmad, Soheili, Amin, Soltani, Shahin, Soltani-Zangbar, Mohammad Sadegh, Soofi, Moslem, Tabaeian, Seidamir Pasha, Tabary, Mohammadreza, Tahamtan, Alireza, Taheri, Majid, Taherkhani, Amir, Tajdini, Masih, Tavolinejad, Hamed, Tehrani-Banihashemi, Arash, Tiyuri, Amir, Tohidast, Seyed Abolfazl, Vakilian, Alireza, Valadan Tahbaz, Sahel, Vo, Bay, Yahyazadeh Jabbari, Seyed Hossein, Yazdi-Feyzabadi, Vahid, Yousefi, Zabihollah, Yousefinezhadi, Taraneh, Zahir, Mazyar, Zahirian Moghadam, Telma, Zamanian, Maryam, Zandian, Hamed, Zangeneh, Alireza, Zarafshan, Hadi, Zare, Fariba, Zare Dehnavi, Ali, Zarea, Kourosh, Zarei, Ahmad, Zareshahrabadi, Zahra, Ziapour, Arash, Zoghi, Sina, Sarrafzadegan, Nizal, Rahimi-Movaghar, Vafa, Jamshidi, Hamid Reza, Mokdad, Ali H, Hay, Simon I, Murray, Christopher J L, Khosravi, Ardeshir, Moradi-Lakeh, Maziar, Asadi-Lari, Mohsen, Malekzadeh, Reza, and Larijani, Bagher

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2022
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28. The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019

Author

Alvarez, Elysia M, Force, Lisa M, Xu, Rixing, Compton, Kelly, Lu, Dan, Henrikson, Hannah Jacqueline, Kocarnik, Jonathan M, Harvey, James D, Pennini, Alyssa, Dean, Frances E, Fu, Weijia, Vargas, Martina T, Keegan, Theresa H M, Ariffin, Hany, Barr, Ronald D, Erdomaeva, Yana Arturovna, Gunasekera, D Sanjeeva, John-Akinola, Yetunde O, Ketterl, Tyler G, Kutluk, Tezer, Malogolowkin, Marcio Henrique, Mathur, Prashant, Radhakrishnan, Venkatraman, Ries, Lynn Ann Gloeckler, Rodriguez-Galindo, Carlos, Sagoyan, Garik Barisovich, Sultan, Iyad, Abbasi, Behzad, Abbasi-Kangevari, Mohsen, Abbasi-Kangevari, Zeinab, Abbastabar, Hedayat, Abdelmasseh, Michael, Abd-Elsalam, Sherief, Abdoli, Amir, Abebe, Haimanot, Abedi, Aidin, Abidi, Hassan, Abolhassani, Hassan, Abubaker Ali, Hiwa, Abu-Gharbieh, Eman, Achappa, Basavaprabhu, Acuna, Juan Manuel, Adedeji, Isaac Akinkunmi, Adegboye, Oyelola A, Adnani, Qorinah Estiningtyas Sakilah, Advani, Shailesh M, Afzal, Muhammad Sohail, Aghaie Meybodi, Mohamad, Ahadinezhad, Bahman, Ahinkorah, Bright Opoku, Ahmad, Sajjad, Ahmadi, Sepideh, Ahmed, Muktar Beshir, Ahmed Rashid, Tarik, Ahmed Salih, Yusra, Aiman, Wajeeha, Akalu, Gizachew Taddesse, Al Hamad, Hanadi, Alahdab, Fares, AlAmodi, Abdulhadi A, Alanezi, Fahad Mashhour, Alanzi, Turki M, Alem, Adugnaw Zeleke, Alem, Dejene Tsegaye, Alemayehu, Yosef, Alhalaiqa, Fadwa Naji, Alhassan, Robert Kaba, Ali, Saqib, Alicandro, Gianfranco, Alipour, Vahid, Aljunid, Syed Mohamed, Alkhayyat, Motasem, Alluri, Sunitha, Almasri, Nihad A, Al-Maweri, Sadeq Ali, Almustanyir, Sami, Al-Raddadi, Rajaa M, Alvis-Guzman, Nelson, Ameyaw, Edward Kwabena, Amini, Saeed, Amu, Hubert, Ancuceanu, Robert, Andrei, Catalina Liliana, Andrei, Tudorel, Ansari, Fereshteh, Ansari-Moghaddam, Alireza, Anvari, Davood, Anyasodor, Anayochukwu Edward, Arabloo, Jalal, Arab-Zozani, Morteza, Argaw, Ayele Mamo, Arshad, Muhammad, Arulappan, Judie, Aryannejad, Armin, Asemi, Zatollah, Asghari Jafarabadi, Mohammad, Atashzar, Mohammad Reza, Atorkey, Prince, Atreya, Alok, Attia, Sameh, Aujayeb, Avinash, Ausloos, Marcel, Avila-Burgos, Leticia, Awedew, Atalel Fentahun, Ayala Quintanilla, Beatriz Paulina, Ayele, Alemu Degu, Ayen, Solomon Shitu, Azab, Mohammed A, Azadnajafabad, Sina, Azami, Hiva, Azangou-Khyavy, Mohammadreza, Azari Jafari, Amirhossein, Azarian, Ghasem, Azzam, Ahmed Y, Bahadory, Saeed, Bai, Jianjun, Baig, Atif Amin, Baker, Jennifer L, Banach, Maciej, Bärnighausen, Till Winfried, Barone-Adesi, Francesco, Barra, Fabio, Barrow, Amadou, Basaleem, Huda, Batiha, Abdul-Monim Mohammad, Behzadifar, Masoud, Bekele, Niguss Cherie, Belete, Rebuma, Belgaumi, Uzma Iqbal, Bell, Arielle Wilder, Berhie, Alemshet Yirga, Bhagat, Devidas S, Bhagavathula, Akshaya Srikanth, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhaskar, Sonu, Bhattacharyya, Krittika, Bhojaraja, Vijayalakshmi S, Bibi, Sadia, Bijani, Ali, Biondi, Antonio, Birara, Setognal, Bjørge, Tone, Bolarinwa, Obasanjo Afolabi, Bolla, Srinivasa Rao, Boloor, Archith, Braithwaite, Dejana, Brenner, Hermann, Bulamu, Norma B, Burkart, Katrin, Bustamante-Teixeira, Maria Teresa, Butt, Nadeem Shafique, Butt, Zahid A, Caetano dos Santos, Florentino Luciano, Cao, Chao, Cao, Yin, Carreras, Giulia, Catalá-López, Ferrán, Cembranel, Francieli, Cerin, Ester, Chakinala, Raja Chandra, Chakraborty, Promit Ananyo, Chattu, Vijay Kumar, Chaturvedi, Pankaj, Chaurasia, Akhilanand, Chavan, Prachi P, Chimed-Ochir, Odgerel, Choi, Jee-Young Jasmine, Christopher, Devasahayam J, Chu, Dinh-Toi, Chung, Michael T, Conde, Joao, Costa, Vera Marisa, Da'ar, Omar B, Dadras, Omid, Dahlawi, Saad M A, Dai, Xiaochen, Damiani, Giovanni, D'Amico, Emanuele, Dandona, Lalit, Dandona, Rakhi, Daneshpajouhnejad, Parnaz, Darwish, Amira Hamed, Daryani, Ahmad, De la Hoz, Fernando Pio, Debela, Sisay Abebe, Demie, Takele Gezahegn G, Demissie, Getu Debalkie, Demissie, Zeleke Geto, Denova-Gutiérrez, Edgar, Derbew Molla, Meseret, Desai, Rupak, Desta, Abebaw Alemayehu, Dhamnetiya, Deepak, Dharmaratne, Samath Dhamminda, Dhimal, Mandira Lamichhane, Dhimal, Meghnath, Dianatinasab, Mostafa, Didehdar, Mojtaba, Diress, Mengistie, Djalalinia, Shirin, Do, Huyen Phuc, Doaei, Saeid, Dorostkar, Fariba, dos Santos, Wendel Mombaque, Drake, Thomas M, Ekholuenetale, Michael, El Sayed, Iman, El Sayed Zaki, Maysaa, El Tantawi, Maha, El-Abid, Hassan, Elbahnasawy, Mostafa Ahmed, Elbarazi, Iffat, Elhabashy, Hala Rashad, Elhadi, Muhammed, El-Jaafary, Shaimaa I, Enyew, Daniel Berhanie, Erkhembayar, Ryenchindorj, Eshrati, Babak, Eskandarieh, Sharareh, Faisaluddin, Mohammed, Fares, Jawad, Farooque, Umar, Fasanmi, Abidemi Omolara, Fatima, Wafa, Ferreira de Oliveira, José Miguel P, Ferrero, Simone, Ferro Desideri, Lorenzo, Fetensa, Getahun, Filip, Irina, Fischer, Florian, Fisher, James L, Foroutan, Masoud, Fukumoto, Takeshi, Gaal, Peter Andras, Gad, Mohamed M, Gaewkhiew, Piyada, Gallus, Silvano, Garg, Tushar, Gebremeskel, Teferi Gebru, Gemeda, Belete Negese Belete, Getachew, Tamiru, Ghafourifard, Mansour, Ghamari, Seyyed-Hadi, Ghashghaee, Ahmad, Ghassemi, Fariba, Ghith, Nermin, Gholami, Ali, Gholizadeh Navashenaq, Jamshid, Gilani, Syed Amir, Ginindza, Themba G, Gizaw, Abraham Tamirat, Glasbey, James C, Goel, Amit, Golechha, Mahaveer, Goleij, Pouya, Golinelli, Davide, Gopalani, Sameer Vali, Gorini, Giuseppe, Goudarzi, Houman, Goulart, Bárbara Niegia Garcia, Grada, Ayman, Gubari, Mohammed Ibrahim Mohialdeen, Guerra, Maximiliano Ribeiro, Guha, Avirup, Gupta, Bhawna, Gupta, Sapna, Gupta, Veer Bala, Gupta, Vivek Kumar, Haddadi, Rasool, Hafezi-Nejad, Nima, Hailu, Alemayehu, Haj-Mirzaian, Arvin, Halwani, Rabih, Hamadeh, Randah R, Hambisa, Mitiku Teshome, Hameed, Sajid, Hamidi, Samer, Haque, Shafiul, Hariri, Sanam, Haro, Josep Maria, Hasaballah, Ahmed I, Hasan, S M Mahmudul, Hashemi, Seyedeh Melika, Hassan, Treska S, Hassanipour, Soheil, Hay, Simon I, Hayat, Khezar, Hebo, Sultan H, Heidari, Golnaz, Heidari, Mohammad, Herrera-Serna, Brenda Yuliana, Herteliu, Claudiu, Heyi, Demisu Zenbaba, Hezam, Kamal, Hole, Michael K, Holla, Ramesh, Horita, Nobuyuki, Hossain, Md Mahbub, Hossain, Mohammad Bellal, Hosseini, Mohammad-Salar, Hosseini, Mostafa, Hosseinzadeh, Ali, Hosseinzadeh, Mehdi, Hostiuc, Mihaela, Hostiuc, Sorin, Househ, Mowafa, Hsairi, Mohamed, Huang, Junjie, Hussein, Nawfal R, Hwang, Bing-Fang, Ibitoye, Segun Emmanuel, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Innos, Kaire, Irham, Lalu Muhammad, Islam, Rakibul M, Islam, Sheikh Mohammed Shariful, Ismail, Nahlah Elkudssiah, Isola, Gaetano, Iwagami, Masao, Jacob, Louis, Jadidi-Niaragh, Farhad, Jain, Vardhmaan, Jakovljevic, Mihajlo, Janghorban, Roksana, Javadi Mamaghani, Amirreza, Jayaram, Shubha, Jayawardena, Ranil, Jazayeri, Seyed Behzad, Jebai, Rime, Jha, Ravi Prakash, Joo, Tamas, Joseph, Nitin, Joukar, Farahnaz, Jürisson, Mikk, Kaambwa, Billingsley, Kabir, Ali, Kalankesh, Leila R, Kaliyadan, Feroze, Kamal, Zul, Kamath, Ashwin, Kandel, Himal, Kar, Sitanshu Sekhar, Karaye, Ibraheem M, Karimi, Amirali, Kassa, Bekalu Getnet, Kauppila, Joonas H, Kemp Bohan, Phillip M, Kengne, Andre Pascal, Kerbo, Amene Abebe, Keykhaei, Mohammad, Khader, Yousef Saleh, Khajuria, Himanshu, Khalili, Nastaran, Khalili, Neda, Khan, Ejaz Ahmad, Khan, Gulfaraz, Khan, Maseer, Khan, Md Nuruzzaman, Khan, Moien AB, Khanali, Javad, Khayamzadeh, Maryam, Khosravizadeh, Omid, Khubchandani, Jagdish, Khundkar, Roba, Kim, Min Seo, Kim, Yun Jin, Kisa, Adnan, Kisa, Sezer, Kissimova-Skarbek, Katarzyna, Kolahi, Ali-Asghar, Kopec, Jacek A, Koteeswaran, Rajasekaran, Koulmane Laxminarayana, Sindhura Lakshmi, Koyanagi, Ai, Kugbey, Nuworza, Kumar, G Anil, Kumar, Nithin, Kwarteng, Alexander, La Vecchia, Carlo, Lan, Qing, Landires, Iván, Lasrado, Savita, Lauriola, Paolo, Ledda, Caterina, Lee, Sang-woong, Lee, Wei-Chen, Lee, Yeong Yeh, Lee, Yo Han, Leigh, James, Leong, Elvynna, Li, Bingyu, Li, Jiarui, Li, Ming-Chieh, Lim, Stephen S, Liu, Xuefeng, Lobo, Stany W, Loureiro, Joana A, Lugo, Alessandra, Lunevicius, Raimundas, Magdy Abd El Razek, Hassan, Magdy Abd El Razek, Muhammed, Mahmoudi, Morteza, Majeed, Azeem, Makki, Alaa, Male, Shilpa, Malekpour, Mohammad-Reza, Malekzadeh, Reza, Malik, Ahmad Azam, Mamun, Mohammed A, Manafi, Navid, Mansour-Ghanaei, Fariborz, Mansouri, Borhan, Mansournia, Mohammad Ali, Martini, Santi, Masoumi, Seyedeh Zahra, Matei, Clara N, Mathur, Manu Raj, McAlinden, Colm, Mehrotra, Ravi, Mendoza, Walter, Menezes, Ritesh G, Mentis, Alexios-Fotios A, Meretoja, Tuomo J, Mersha, Amanual Getnet, Mesregah, Mohamed Kamal, Mestrovic, Tomislav, Miao Jonasson, Junmei, Miazgowski, Bartosz, Michalek, Irmina Maria, Miller, Ted R, Mingude, Alemu Basazin, Mirmoeeni, Seyyedmohammadsadeq, Mirzaei, Hamed, Misra, Sanjeev, Mithra, Prasanna, Mohammad, Karzan Abdulmuhsin, Mohammadi, Mokhtar, Mohammadi, Seyyede Momeneh, Mohammadian-Hafshejani, Abdollah, Mohammadpourhodki, Reza, Mohammed, Arif, Mohammed, Shafiu, Mohammed, Teroj Abdulrahman, Moka, Nagabhishek, Mokdad, Ali H, Molokhia, Mariam, Momtazmanesh, Sara, Monasta, Lorenzo, Moni, Mohammad Ali, Moradi, Ghobad, Moradi, Yousef, Moradzadeh, Maliheh, Moradzadeh, Rahmatollah, Moraga, Paula, Morrison, Shane Douglas, Mostafavi, Ebrahim, Mousavi Khaneghah, Amin, Mpundu-Kaambwa, Christine, Mubarik, Sumaira, Mwanri, Lillian, Nabhan, Ashraf F, Nagaraju, Shankar Prasad, Nagata, Chie, Naghavi, Mohsen, Naimzada, Mukhammad David, Naldi, Luigi, Nangia, Vinay, Naqvi, Atta Abbas, Narasimha Swamy, Sreenivas, Narayana, Aparna Ichalangod, Nayak, Biswa Prakash, Nayak, Vinod C, Nazari, Javad, Nduaguba, Sabina Onyinye, Negoi, Ionut, Negru, Serban Mircea, Nejadghaderi, Seyed Aria, Nepal, Samata, Neupane Kandel, Sandhya, Nggada, Haruna Asura, Nguyen, Cuong Tat, Nnaji, Chukwudi A, Nosrati, Hamed, Nouraei, Hasti, Nowroozi, Ali, Nuñez-Samudio, Virginia, Nwatah, Vincent Ebuka, Nzoputam, Chimezie Igwegbe, Oancea, Bogdan, Odukoya, Oluwakemi Ololade, Oguntade, Ayodipupo Sikiru, Oh, In-Hwan, Olagunju, Andrew T, Olagunju, Tinuke O, Olakunde, Babayemi Oluwaseun, Oluwasanu, Mojisola Morenike, Omar, Emad, Omar Bali, Ahmed, Ong, Sokking, Onwujekwe, Obinna E, Ortega-Altamirano, Doris V, Otstavnov, Nikita, Otstavnov, Stanislav S, Oumer, Bilcha, Owolabi, Mayowa O, P A, Mahesh, Padron-Monedero, Alicia, Padubidri, Jagadish Rao, Pakshir, Keyvan, Pana, Adrian, Pandey, Anamika, Pardhan, Shahina, Pashazadeh Kan, Fatemeh, Pasovic, Maja, Patel, Jenil R, Pati, Siddhartha, Pattanshetty, Sanjay M, Paudel, Uttam, Pereira, Renato B, Peres, Mario F P, Perianayagam, Arokiasamy, Postma, Maarten J, Pourjafar, Hadi, Pourshams, Akram, Prashant, Akila, Pulakunta, Thejodhar, Qadir, Mirza Muhammad Fahd Fahd, Rabiee, Mohammad, Rabiee, Navid, Radfar, Amir, Radhakrishnan, Raghu Anekal, Rafiee, Ata, Rafiei, Alireza, Rafiei, Sima, Rahim, Fakher, Rahimzadeh, Shadi, Rahman, Mosiur, Rahman, Muhammad Aziz, Rahmani, Amir Masoud, Rajesh, Aashish, Ramezani-Doroh, Vajiheh, Ranabhat, Kamal, Ranasinghe, Priyanga, Rao, Chythra R, Rao, Sowmya J, Rashedi, Sina, Rashidi, Mahsa, Rashidi, Mohammad-Mahdi, Rath, Goura Kishor, Rawaf, David Laith, Rawaf, Salman, Rawal, Lal, Rawassizadeh, Reza, Razeghinia, Mohammad Sadegh, Regasa, Misganu Teshoma, Renzaho, Andre M N, Rezaei, Maryam, Rezaei, Negar, Rezaei, Nima, Rezaeian, Mohsen, Rezapour, Aziz, Rezazadeh-Khadem, Sahba, Riad, Abanoub, Rios Lopez, Ligia Estefania, Rodriguez, Jefferson Antonio Buendia, Ronfani, Luca, Roshandel, Gholamreza, Rwegerera, Godfrey M, Saber-Ayad, Maha Mohamed, Sabour, Siamak, Saddik, Basema, Sadeghi, Erfan, Sadeghian, Saeid, Saeed, Umar, Sahebkar, Amirhossein, Saif-Ur-Rahman, KM, Sajadi, S Mohammad, Salahi, Sarvenaz, Salehi, Sana, Salem, Marwa Rashad, Salimzadeh, Hamideh, Samy, Abdallah M, Sanabria, Juan, Sanmarchi, Francesco, Sarveazad, Arash, Sathian, Brijesh, Sawhney, Monika, Sawyer, Susan M, Saylan, Mete, Schneider, Ione Jayce Ceola, Seidu, Abdul-Aziz, Šekerija, Mario, Sendo, Endalew Gemechu, Sepanlou, Sadaf G, Seylani, Allen, Seyoum, Kenbon, Sha, Feng, Shafaat, Omid, Shaikh, Masood Ali, Shamsoddin, Erfan, Shannawaz, Mohammed, Sharma, Rajesh, Sheikhbahaei, Sara, Shetty, Adithi, Shetty, B Suresh Kumar, Shetty, Pavanchand H, Shin, Jae Il, Shirkoohi, Reza, Shivakumar, K M, Shobeiri, Parnian, Siabani, Soraya, Sibhat, Migbar Mekonnen, Siddappa Malleshappa, Sudeep K, Sidemo, Negussie Boti, Silva, Diego Augusto Santos, Silva Julian, Guilherme, Singh, Achintya Dinesh, Singh, Jasvinder A, Singh, Jitendra Kumar, Singh, Surjit, Sinke, Abiy H, Sintayehu, Yitagesu, Skryabin, Valentin Yurievich, Skryabina, Anna Aleksandrovna, Smith, Lee, Sofi-Mahmudi, Ahmad, Soltani-Zangbar, Mohammad Sadegh, Song, Suhang, Spurlock, Emma Elizabeth, Steiropoulos, Paschalis, Straif, Kurt, Subedi, Ranjeeta, Sufiyan, Mu'awiyyah Babale, Suliankatchi Abdulkader, Rizwan, Sultana, Saima, Szerencsés, Viktória, Szócska, Miklós, Tabaeian, Seidamir Pasha, Tabarés-Seisdedos, Rafael, Tabary, Mohammadreza, Tabuchi, Takahiro, Tadbiri, Hooman, Taheri, Majid, Taherkhani, Amir, Takahashi, Ken, Tampa, Mircea, Tan, Ker-Kan, Tat, Vivian Y, Tavakoli, Ahmad, Tbakhi, Abdelghani, Tehrani-Banihashemi, Arash, Temsah, Mohamad-Hani, Tesfay, Fisaha Haile, Tesfaye, Bekele, Thakur, Jarnail Singh, Thapar, Rekha, Thavamani, Aravind, Thiyagarajan, Arulmani, Thomas, Nihal, Tobe-Gai, Ruoyan, Togtmol, Munkhsaikhan, Tohidast, Seyed Abolfazl, Tohidinik, Hamid Reza, Tolani, Musliu Adetola, Tollosa, Daniel Nigusse, Touvier, Mathilde, Tovani-Palone, Marcos Roberto, Traini, Eugenio, Tran, Bach Xuan, Tran, Mai Thi Ngoc, Tripathy, Jaya Prasad, Tusa, Biruk Shalmeno, Ukke, Gebresilasea Gendisha, Ullah, Irfan, Ullah, Saif, Umapathi, Krishna Kishore, Unnikrishnan, Bhaskaran, Upadhyay, Era, Ushula, Tolassa Wakayo, Vacante, Marco, Valadan Tahbaz, Sahel, Varthya, Shoban Babu, Veroux, Massimiliano, Villeneuve, Paul J, Violante, Francesco S, Vlassov, Vasily, Vu, Giang Thu, Waheed, Yasir, Wang, Ning, Ward, Paul, Weldesenbet, Adisu Birhanu, Wen, Yi Feng, Westerman, Ronny, Winkler, Andrea Sylvia, Wubishet, Befikadu Legesse, Xu, Suowen, Yahyazadeh Jabbari, Seyed Hossein, Yang, Lin, Yaya, Sanni, Yazdi-Feyzabadi, Vahid, Yazie, Taklo Simeneh, Yehualashet, Sisay Shewasinad, Yeshaneh, Alex, Yeshaw, Yigizie, Yirdaw, Birhanu Wubale, Yonemoto, Naohiro, Younis, Mustafa Z, Yousefi, Zabihollah, Yu, Chuanhua, Yunusa, Ismaeel, Zadnik, Vesna, Zahir, Mazyar, Zahirian Moghadam, Telma, Zamani, Mohammad, Zamanian, Maryam, Zandian, Hamed, Zare, Fariba, Zastrozhin, Mikhail Sergeevich, Zastrozhina, Anasthasia, Zhang, Jianrong, Zhang, Zhi-Jiang, Ziapour, Arash, Zoladl, Mohammad, Murray, Christopher J L, Fitzmaurice, Christina, Bleyer, Archie, and Bhakta, Nickhill

Published
2022
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32. Conservative Management of Penile and Urethral Lichen Sclerosus: A Systematic Review.

Author

Shieh, Christine, Hakam, Nizar, Pearce, Robert J., Nagpal, Meera, Ghaffar, Umar, Guzman, Jose L., Abbasi, Behzad, Shaw, Nathan M., Jones, Charles P., Breyer, Benjamin N., and Johnsen, Niels V.

Abstract

Purpose: We evaluate the efficacy and safety profiles of currently available conservative management options for penile and urethral lichen sclerosus. Materials and Methods: A systematic review of existing literature on lichen sclerosus was conducted utilizing the PubMed, Embase, and Web of Science databases. References were assessed for relevance to nonsurgical management of male genital lichen sclerosus by title and abstract by 3 independent reviewers, then reviewed in full and in duplicate by 5 independent reviewers. Results: Seventeen studies describing conservative management of histologically confirmed penile and urethral lichen sclerosus in male patients were included in the final review. We present available evidence supporting the use of 4 major treatment modalities represented in the existing literature: topical corticosteroids, tacrolimus, platelet-rich plasma, and CO2 laser. We also briefly discuss the limited studies on the use of oral acitretin and polydeoxyribonucleotide injections. Outcomes assessed include symptoms, clinical appearance, quality of life, sexual satisfaction, adverse effects, and long-term efficacy of treatment. Conclusions: Topical corticosteroids remain the mainstay of conservative management of penile and urethral lichen sclerosus, with current literature supporting the use of other therapies such as tacrolimus and platelet-rich plasma as alternatives or adjuvant treatments when escalation of treatment is necessary. Future research should further explore the efficacy and safety of newer therapies through additional controlled clinical trials in the targeted population. [ABSTRACT FROM AUTHOR]

Published
2024
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33. Oral phosphodiesterase type 5 inhibitors and priapism: A VigiBase analysis.

Author

Abbasi, Behzad, Shaw, Nathan M., Lui, Jason L., Hakam, Nizar, Nabavizadeh, Behnam, and Breyer, Benjamin N.

Abstract

Purpose: To explore the differences of priapism events among a diverse cohort taking erectogenic medicines (i.e., phosphodiesterase type 5 inhibitors [PDE5i] and intracavernousal drugs). Method s : We queried the World Health Organization global database of individual case safety reports (VigiBase) for records of the adverse drug reactions (ADR) with sildenafil, tadalafil, avanafil, vardenafil, papaverine, and alprostadil. Disproportionality analyses (case/non‐case approach) were performed to assess the reporting odds ratio (ROR) of priapism reporting in PDE5i consumers compared to intracavernousal drug recipients. Results: From a total of 133 819 ADR events for erectogenic medications, 632 were priapism (PDE5is: n = 550, 0.41%; intracavernousal drugs: n = 82, 9.92%). Priapism disproportionality signals from intracavernousal drugs were 25 times stronger than PDE5is (ROR = 34.7; confidence interval [CI] 95%: 27.12–43.94 vs. ROR = 1.38; 95% CI: 1.24–1.54). For all PDE5i agents, the 12–17 years age group had the highest ROR (9.49, 95% CI: 3.76–19.93) followed by 2–11 years (4.31, 95% CI: 1.57–9.4). Disproportionality signals for consumers under 18 for both all PDE5is as a whole (ROR = 4.57, 95% CI: 2.48–7.73) and sildenafil (ROR = 4.89, 95% CI: 2.51–8.62) were stronger than individuals 18 or older (ROR = 1.06, 95% CI: 0.93–1.21 and ROR = 1.08, 95% CI: 0.91–1.26, respectively). Conclusions: PDE5i use shows disproportionate priapism signals which are higher in young patients. [ABSTRACT FROM AUTHOR]

Published
2024
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40. Adverse reactions of PDE5 inhibitors: An analysis of the World Health Organization pharmacovigilance database.

Author

Lui, Jason L., Shaw, Nathan M., Abbasi, Behzad, Hakam, Nizar, and Breyer, Benjamin N.

Subjects
PHOSPHODIESTERASE inhibitors, PHOSPHODIESTERASE-5 inhibitors, DRUG side effects, DATABASES, PRIAPISM, IMPOTENCE, WORLD health
Abstract

Background: Despite their efficacy and general safety, rare but devastating adverse drug reactions have been associated with phosphodiesterase type 5 inhibitors. Objectives: To determine the safety profile of oral phosphodiesterase type 5 inhibitors with a particular focus on priapism and malignant melanoma. Materials and methods: In this case–non‐case study, we queried the individual case safety reports for phosphodiesterase type 5 inhibitors within the World Health Organization global database of individual case safety reports (VigiBase) between 1983 and 2021. We included all individual case safety reports for sildenafil, tadalafil, vardenafil, and avanafil in men. For comparison, we also extracted the safety data from the Food and Drug Administration trials for these drugs. We assessed the safety profile of phosphodiesterase type 5 inhibitors by disproportionality analysis by measuring reporting odds ratio for their most commonly reported adverse drug reactions, once for all phosphodiesterase type 5 inhibitor reports and once for reports of oral phosphodiesterase type 5 inhibitor use in adult men (≥18 years old) with sexual dysfunction. Results: A total of 94,713 individual case safety reports for phosphodiesterase type 5 inhibitors were extracted. A total of 31,827 individual case safety reports were identified relating to adult men taking oral sildenafil, tadalafil, vardenafil, or avanafil for sexual dysfunction. The most common adverse drug reactions included poor drug efficacy (42.5%), headache (10.4% vs. 8.5%–27.6% [Food and Drug Administration]), abnormal vision (8.4% vs. ≤4.6% [Food and Drug Administration]), flushing (5.2% vs. 5.1%–16.5% [Food and Drug Administration]), and dyspepsia (4.2% vs. 3.4%–11.1% [Food and Drug Administration]). Priapism showed significant signals for sildenafil (reporting odds ratio = 13.81, 95% confidence interval: 11.75–16.24), tadalafil (reporting odds ratio = 14.54, 95% confidence interval: 11.56–18.06), and vardenafil (reporting odds ratio = 14.12, 95% confidence interval: 8.36–22.35). Comparing with other medications in VigiBase, sildenafil (reporting odds ratio = 8.73, 95% confidence interval: 7.63–9.99) and tadalafil (reporting odds ratio = 4.25, 95% confidence interval: 3.19–5.55) had significantly higher reporting odds ratios for malignant melanoma. Conclusion: Phosphodiesterase type 5 inhibitors show significant signals correlating with priapism among a large international cohort. Further clinical study is needed to elucidate whether this is from proper or inappropriate use or other confounding conditions, as analysis of pharmacovigilance data does not allow for quantifying the clinical risk. Also, there appears to be a relationship between phosphodiesterase type 5 inhibitor use and malignant melanoma, which warrants additional study to better understand causation. [ABSTRACT FROM AUTHOR]

Published
2023
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43. Radiation-induced fistulas in patients with prior pelvic radiotherapy for prostate cancer: a systematic review and meta-analysis

Author

Sadighian, Michael, primary, Hakam, Nizar, additional, Amend, Gregory, additional, Shaw, Nathan M., additional, Tahir, Peggy, additional, Allen, I. Elaine, additional, Nabavizadeh, Behnam, additional, Holler, Jordan, additional, Shibley, William, additional, Li, Kevin D., additional, Abbasi, Behzad, additional, Bell, Alexander, additional, Mohamad, Osama, additional, and Breyer, Benjamin N., additional

Published
2023
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45. The global, regional, and national burden of benign prostatic hyperplasia in 204 countries and territories from 2000 to 2019: a systematic analysis for the Global Burden of Disease Study 2019

Author

Awedew, Atalel Fentahun, primary, Han, Hannah, additional, Abbasi, Behzad, additional, Abbasi-Kangevari, Mohsen, additional, Ahmed, Muktar Beshir, additional, Almidani, Omar, additional, Amini, Erfan, additional, Arabloo, Jalal, additional, Argaw, Ayele Mamo, additional, Athari, Seyyed Shamsadin, additional, Atlaw, Daniel, additional, Banach, Maciej, additional, Barrow, Amadou, additional, Bhagavathula, Akshaya Srikanth, additional, Bhojaraja, Vijayalakshmi S, additional, Bikbov, Boris, additional, Bodicha, Belay Boda Abule, additional, Butt, Nadeem Shafique, additional, Caetano dos Santos, Florentino Luciano, additional, Dadras, Omid, additional, Dai, Xiaochen, additional, Doan, Linh Phuong, additional, Eftekharzadeh, Sahar, additional, Fatehizadeh, Ali, additional, Garg, Tushar, additional, Gebremeskel, Teferi Gebru, additional, Getachew, Motuma Erena, additional, Ghamari, Seyyed-Hadi, additional, Gilani, Syed Amir, additional, Golechha, Mahaveer, additional, Gupta, Veer Bala, additional, Gupta, Vivek Kumar, additional, Hay, Simon I, additional, Hosseini, Mohammad-Salar, additional, Hosseinzadeh, Mehdi, additional, Humayun, Ayesha, additional, Ilic, Irena M, additional, Ilic, Milena D, additional, Ismail, Nahlah Elkudssiah, additional, Jakovljevic, Mihajlo, additional, Jayaram, Shubha, additional, Jazayeri, Seyed Behzad, additional, Jema, Alelign Tasew, additional, Kabir, Ali, additional, Karaye, Ibraheem M, additional, Khader, Yousef Saleh, additional, Khan, Ejaz Ahmad, additional, Landires, Iván, additional, Lee, Sang-woong, additional, Lee, Shaun Wen Huey, additional, Lim, Stephen S, additional, Lobo, Stany W, additional, Majeed, Azeem, additional, Malekpour, Mohammad-Reza, additional, Malih, Narges, additional, Malik, Ahmad Azam, additional, Mehrabi Nasab, Entezar, additional, Mestrovic, Tomislav, additional, Michalek, Irmina Maria, additional, Mihrtie, Gedefaye Nibret, additional, Mirza-Aghazadeh-Attari, Mohammad, additional, Misganaw, Awoke Temesgen, additional, Mokdad, Ali H, additional, Molokhia, Mariam, additional, Murray, Christopher J L, additional, Narasimha Swamy, Sreenivas, additional, Nguyen, Son Hoang, additional, Nowroozi, Ali, additional, Nuñez-Samudio, Virginia, additional, Owolabi, Mayowa O, additional, Pawar, Shrikant, additional, Perico, Norberto, additional, Rawaf, David Laith, additional, Rawaf, Salman, additional, Rawassizadeh, Reza, additional, Remuzzi, Giuseppe, additional, Sahebkar, Amirhossein, additional, Sampath, Chethan, additional, Shetty, Jeevan K, additional, Sibhat, Migbar Mekonnen, additional, Singh, Jasvinder A, additional, Tan, Ker-Kan, additional, Temesgen, Gebremaryam, additional, Tolani, Musliu Adetola, additional, Tovani-Palone, Marcos Roberto, additional, Valadan Tahbaz, Sahel, additional, Valizadeh, Rohollah, additional, Vo, Bay, additional, Vu, Linh Gia, additional, Yang, Lin, additional, Yazdanpanah, Fereshteh, additional, Yigit, Arzu, additional, Yiğit, Vahit, additional, Yunusa, Ismaeel, additional, Zahir, Mazyar, additional, Vos, Theo, additional, and Dirac, M Ashworth, additional

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2022
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47. a systematic analysis for the Global Burden of Disease Study 2019

Author

Tran, Khanh Bao, Lang, Justin J, Compton, Kelly, Xu, Rixing, Acheson, Alistair R, Henrikson, Hannah Jacqueline, Kocarnik, Jonathan M, Penberthy, Louise, Aali, Amirali, Abbas, Qamar, Abbasi, Behzad, Abbasi-kangevari, Mohsen, Abbasi-kangevari, Zeinab, Abbastabar, Hedayat, Abdelmasseh, Michael, Abd-elsalam, Sherief, Abdelwahab, Ahmed Abdelwahab, Abdoli, Gholamreza, Abdulkadir, Hanan Abdulkadir, Abedi, Aidin, Abegaz, Kedir Hussein, Abidi, Hassan, Aboagye, Richard Gyan, Abolhassani, Hassan, Absalan, Abdorrahim, Abtew, Yonas Derso, Abubaker Ali, Hiwa, Abu-gharbieh, Eman, Achappa, Basavaprabhu, Acuna, Juan Manuel, Addison, Daniel, Addo, Isaac Yeboah, Adegboye, Oyelola A, Adesina, Miracle Ayomikun, Adnan, Mohammad, Adnani, Qorinah Estiningtyas Sakilah, Advani, Shailesh M, Afrin, Sumia, Afzal, Muhammad Sohail, Aggarwal, Manik, Ahinkorah, Bright Opoku, Ahmad, Araz Ramazan, Ahmad, Rizwan, Ahmad, Sajjad, Ahmad, Sohail, Ahmadi, Sepideh, Ahmed, Haroon, Ahmed, Luai A, Ahmed, Muktar Beshir, Ahmed Rashid, Tarik, Aiman, Wajeeha, Ajami, Marjan, Akalu, Gizachew Taddesse, Akbarzadeh-khiavi, Mostafa, Aklilu, Addis, Akonde, Maxwell, Akunna, Chisom Joyqueenet, Al Hamad, Hanadi, Alahdab, Fares, Alanezi, Fahad Mashhour, Alanzi, Turki M, Alessy, Saleh Ali, Algammal, Abdelazeem M, Al-hanawi, Mohammed Khaled, Alhassan, Robert Kaba, Ali, Beriwan Abdulqadir, Ali, Liaqat, Ali, Syed Shujait, Alimohamadi, Yousef, Alipour, Vahid, Aljunid, Syed Mohamed, Alkhayyat, Motasem, Al-maweri, Sadeq Ali Ali, Almustanyir, Sami, Alonso, Nivaldo, Alqalyoobi, Shehabaldin, Al-raddadi, Rajaa M, Al-rifai, Rami H Hani, Al-sabah, Salman Khalifah, Al-tammemi, Ala'a B, Altawalah, Haya, Alvis-guzman, Nelson, Amare, Firehiwot, Ameyaw, Edward Kwabena, Aminian Dehkordi, Javad Javad, Amirzade-iranaq, Mohammad Hosein, Amu, Hubert, Amusa, Ganiyu Adeniyi, Ancuceanu, Robert, Anderson, Jason A, Animut, Yaregal Animut, Anoushiravani, Amir, Anoushirvani, Ali Arash, Ansari-moghaddam, Alireza, Ansha, Mustafa Geleto, Antony, Benny, Antwi, Maxwell Hubert, Anwar, Sumadi Lukman, Anwer, Razique, Anyasodor, Anayochukwu Edward, Arabloo, Jalal, Arab-zozani, Morteza, Aremu, Olatunde, Argaw, Ayele Mamo, Ariffin, Hany, Aripov, Timur, Arshad, Muhammad, Artaman, Al, Arulappan, Judie, Aruleba, Raphael Taiwo, Aryannejad, Armin, Asaad, Malke, Asemahagn, Mulusew A, Asemi, Zatollah, Asghari-jafarabadi, Mohammad, Ashraf, Tahira, Assadi, Reza, Athar, Mohammad, Athari, Seyyed Shamsadin, Atout, Maha Moh'd Wahbi, Attia, Sameh, Aujayeb, Avinash, Ausloos, Marcel, Avila-burgos, Leticia, Awedew, Atalel Fentahun, Awoke, Mamaru Ayenew, Awoke, Tewachew, Ayala Quintanilla, Beatriz Paulina, Ayana, Tegegn Mulatu, Ayen, Solomon Shitu, Azadi, Davood, Azadnajafabad, Sina, Azami-aghdash, Saber, Azanaw, Melkalem Mamuye, Azangou-khyavy, Mohammadreza, Azari Jafari, Amirhossein, Azizi, Hosein, Azzam, Ahmed Y Y, Babajani, Amirhesam, Badar, Muhammad, Badiye, Ashish D, Baghcheghi, Nayereh, Bagheri, Nader, Bagherieh, Sara, Bahadory, Saeed, Baig, Atif Amin, Baker, Jennifer L, Bakhtiari, Ahad, Bakshi, Ravleen Kaur, Banach, Maciej, Banerjee, Indrajit, Bardhan, Mainak, Barone-adesi, Francesco, Barra, Fabio, Barrow, Amadou, Bashir, Nasir Z, Bashiri, Azadeh, Basu, Saurav, Batiha, Abdul-monim Mohammad, Begum, Aeysha, Bekele, Alehegn Bekele, Belay, Alemayehu Sayih, Belete, Melaku Ashagrie, Belgaumi, Uzma Iqbal, Bell, Arielle Wilder, Belo, Luis, Benzian, Habib, Berhie, Alemshet Yirga, Bermudez, Amiel Nazer C, Bernabe, Eduardo, Bhagavathula, Akshaya Srikanth, Bhala, Neeraj, Bhandari, Bharti Bhandari, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhattacharyya, Krittika, Bhojaraja, Vijayalakshmi S, Bhuyan, Soumitra S, Bibi, Sadia, Bilchut, Awraris Hailu, Bintoro, Bagas Suryo, Biondi, Antonio, Birega, Mesfin Geremaw Birega, Birhan, Habitu Eshetu, Bjørge, Tone, Blyuss, Oleg, Bodicha, Belay Boda Abule, Bolla, Srinivasa Rao, Boloor, Archith, Bosetti, Cristina, Braithwaite, Dejana, Brauer, Michael, Brenner, Hermann, Briko, Andrey Nikolaevich, Briko, Nikolay Ivanovich, Buchanan, Christina Maree, Bulamu, Norma B, Bustamante-teixeira, Maria Teresa, Butt, Muhammad Hammad, Butt, Nadeem Shafique, Butt, Zahid A, Caetano Dos Santos, Florentino Luciano, Cámera, Luis Alberto, Cao, Chao, Cao, Yin, Carreras, Giulia, Carvalho, Márcia, Cembranel, Francieli, Cerin, Ester, Chakraborty, Promit Ananyo, Charalampous, Periklis, Chattu, Vijay Kumar, Chimed-ochir, Odgerel, Chirinos-caceres, Jesus Lorenzo, Cho, Daniel Youngwhan, Cho, William C S, Christopher, Devasahayam J, Chu, Dinh-toi, Chukwu, Isaac Sunday, Cohen, Aaron J, Conde, Joao, Cortés, Sandra, Costa, Vera Marisa, Cruz-martins, Natália, Culbreth, Garland T, Dadras, Omid, Dagnaw, Fentaw Teshome, Dahlawi, Saad M A, Dai, Xiaochen, Dandona, Lalit, Dandona, Rakhi, Daneshpajouhnejad, Parnaz, Danielewicz, Anna, Dao, An Thi Minh, Darvishi Cheshmeh Soltani, Reza, Darwesh, Aso Mohammad, Das, Saswati, Davitoiu, Dragos Virgil, Davtalab Esmaeili, Elham, De La Hoz, Fernando Pio, Debela, Sisay Abebe, Dehghan, Azizallah, Demisse, Biniyam, Demisse, Fitsum Wolde, Denova-gutiérrez, Edgar, Derakhshani, Afshin, Derbew Molla, Meseret, Dereje, Diriba, Deribe, Kalkidan Solomon, Desai, Rupak, Desalegn, Markos Desalegn, Dessalegn, Fikadu Nugusu, Dessalegni, Samuel Abebe A, Dessie, Gashaw, Desta, Abebaw Alemayehu, Dewan, Syed Masudur Rahman, Dharmaratne, Samath Dhamminda, Dhimal, Meghnath, Dianatinasab, Mostafa, Diao, Nancy, Diaz, Daniel, Digesa, Lankamo Ena, Dixit, Shilpi Gupta, Doaei, Saeid, Doan, Linh Phuong, Doku, Paul Narh, Dongarwar, Deepa, Dos Santos, Wendel Mombaque, Driscoll, Tim Robert, Dsouza, Haneil Larson, Durojaiye, Oyewole Christopher, Edalati, Sareh, Eghbalian, Fatemeh, Ehsani-chimeh, Elham, Eini, Ebrahim, Ekholuenetale, Michael, Ekundayo, Temitope Cyrus, Ekwueme, Donatus U, El Tantawi, Maha, Elbahnasawy, Mostafa Ahmed, Elbarazi, Iffat, Elghazaly, Hesham, Elhadi, Muhammed, El-huneidi, Waseem, Emamian, Mohammad Hassan, Engelbert Bain, Luchuo, Enyew, Daniel Berhanie, Erkhembayar, Ryenchindorj, Eshetu, Tegegne, Eshrati, Babak, Eskandarieh, Sharareh, Espinosa-montero, Juan, Etaee, Farshid, Etemadimanesh, Azin, Eyayu, Tahir, Ezeonwumelu, Ifeanyi Jude, Ezzikouri, Sayeh, Fagbamigbe, Adeniyi Francis, Fahimi, Saman, Fakhradiyev, Ildar Ravisovich, Faraon, Emerito Jose A, Fares, Jawad, Farmany, Abbas, Farooque, Umar, Farrokhpour, Hossein, Fasanmi, Abidemi Omolara, Fatehizadeh, Ali, Fatima, Wafa, Fattahi, Hamed, Fekadu, Ginenus, Feleke, Berhanu Elfu, Ferrari, Allegra Allegra, Ferrero, Simone, Ferro Desideri, Lorenzo, Filip, Irina, Fischer, Florian, Foroumadi, Roham, Foroutan, Masoud, Fukumoto, Takeshi, Gaal, Peter Andras, Gad, Mohamed M, Gadanya, Muktar A, Gaipov, Abduzhappar, Galehdar, Nasrin, Gallus, Silvano, Garg, Tushar, Gaspar Fonseca, Mariana, Gebremariam, Yosef Haile, Gebremeskel, Teferi Gebru, Gebremichael, Mathewos Alemu, Geda, Yohannes Fikadu, Gela, Yibeltal Yismaw, Gemeda, Belete Negese Belete, Getachew, Melaku, Getachew, Motuma Erena, Ghaffari, Kazem, Ghafourifard, Mansour, Ghamari, Seyyed-hadi, Ghasemi Nour, Mohammad, Ghassemi, Fariba, Ghimire, Ajnish, Ghith, Nermin, Gholamalizadeh, Maryam, Gholizadeh Navashenaq, Jamshid, Ghozy, Sherief, Gilani, Syed Amir, Gill, Paramjit Singh, Ginindza, Themba G, Gizaw, Abraham Tamirat T, Glasbey, James C, Godos, Justyna, Goel, Amit, Golechha, Mahaveer, Goleij, Pouya, Golinelli, Davide, Golitaleb, Mohamad, Gorini, Giuseppe, Goulart, Bárbara Niegia Garcia, Grosso, Giuseppe, Guadie, Habtamu Alganeh, Gubari, Mohammed Ibrahim Mohialdeen, Gudayu, Temesgen Worku, Guerra, Maximiliano Ribeiro, Gunawardane, Damitha Asanga, Gupta, Bhawna, Gupta, Sapna, Gupta, Veer Bala, Gupta, Vivek Kumar, Gurara, Mekdes Kondale, Guta, Alemu, Habibzadeh, Parham, Haddadi Avval, Atlas, Hafezi-nejad, Nima, Hajj Ali, Adel, Haj-mirzaian, Arvin, Halboub, Esam S, Halimi, Aram, Halwani, Rabih, Hamadeh, Randah R, Hameed, Sajid, Hamidi, Samer, Hanif, Asif, Hariri, Sanam, Harlianto, Netanja I, Haro, Josep Maria, Hartono, Risky Kusuma, Hasaballah, Ahmed I, Hasan, S M Mahmudul, Hasani, Hamidreza, Hashemi, Seyedeh Melika, Hassan, Abbas M, Hassanipour, Soheil, Hayat, Khezar, Heidari, Golnaz, Heidari, Mohammad, Heidarymeybodi, Zahra, Herrera-serna, Brenda Yuliana, Herteliu, Claudiu, Hezam, Kamal, Hiraike, Yuta, Hlongwa, Mbuzeleni Mbuzeleni, Holla, Ramesh, Holm, Marianne, Horita, Nobuyuki, Hoseini, Mohammad, Hossain, Md Mahbub, Hossain, Mohammad Bellal Hossain, Hosseini, Mohammad-salar, Hosseinzadeh, Ali, Hosseinzadeh, Mehdi, Hostiuc, Mihaela, Hostiuc, Sorin, Househ, Mowafa, Huang, Junjie, Hugo, Fernando N, Humayun, Ayesha, Hussain, Salman, Hussein, Nawfal R, Hwang, Bing-fang, Ibitoye, Segun Emmanuel, Iftikhar, Pulwasha Maria, Ikuta, Kevin S, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Immurana, Mustapha, Innos, Kaire, Iranpour, Pooya, Irham, Lalu Muhammad, Islam, Md Shariful, Islam, Rakibul M, Islami, Farhad, Ismail, Nahlah Elkudssiah, Isola, Gaetano, Iwagami, Masao, J, Linda Merin, Jaiswal, Abhishek, Jakovljevic, Mihajlo, Jalili, Mahsa, Jalilian, Shahram, Jamshidi, Elham, Jang, Sung-in, Jani, Chinmay T, Javaheri, Tahereh, Jayarajah, Umesh Umesh, Jayaram, Shubha, Jazayeri, Seyed Behzad, Jebai, Rime, Jemal, Bedru, Jeong, Wonjeong, Jha, Ravi Prakash, Jindal, Har Ashish, John-akinola, Yetunde O, Jonas, Jost B, Joo, Tamas, Joseph, Nitin, Joukar, Farahnaz, Jozwiak, Jacek Jerzy, Jürisson, Mikk, Kabir, Ali, Kacimi, Salah Eddine Oussama, Kadashetti, Vidya, Kahe, Farima, Kakodkar, Pradnya Vishal, Kalankesh, Laleh R, Kalankesh, Leila R, Kalhor, Rohollah, Kamal, Vineet Kumar, Kamangar, Farin, Kamath, Ashwin, Kanchan, Tanuj, Kandaswamy, Eswar, Kandel, Himal, Kang, Hyejung, Kanno, Girum Gebremeskel, Kapoor, Neeti, Kar, Sitanshu Sekhar, Karanth, Shama D, Karaye, Ibraheem M, Karch, André, Karimi, Amirali, Kassa, Bekalu Getnet, Katoto, Patrick Dmc, Kauppila, Joonas H, Kaur, Harkiran, Kebede, Abinet Gebremickael, Keikavoosi-arani, Leila, Kejela, Gemechu Gemechu, Kemp Bohan, Phillip M, Keramati, Maryam, Keykhaei, Mohammad, Khajuria, Himanshu, Khan, Abbas, Khan, Abdul Aziz Khan, Khan, Ejaz Ahmad, Khan, Gulfaraz, Khan, Md Nuruzzaman, Khan, Moien Ab, Khanali, Javad, Khatab, Khaled, Khatatbeh, Moawiah Mohammad, Khatib, Mahalaqua Nazli, Khayamzadeh, Maryam, Khayat Kashani, Hamid Reza, Khazeei Tabari, Mohammad Amin, Khezeli, Mehdi, Khodadost, Mahmoud, Kim, Min Seo, Kim, Yun Jin, Kisa, Adnan, Kisa, Sezer, Klugar, Miloslav, Klugarová, Jitka, Kolahi, Ali-asghar, Kolkhir, Pavel, Kompani, Farzad, Koul, Parvaiz A, Koulmane Laxminarayana, Sindhura Lakshmi, Koyanagi, Ai, Krishan, Kewal, Krishnamoorthy, Yuvaraj, Kucuk Bicer, Burcu, Kugbey, Nuworza, Kulimbet, Mukhtar, Kumar, Akshay, Kumar, G Anil, Kumar, Narinder, Kurmi, Om P, Kuttikkattu, Ambily, La Vecchia, Carlo, Lahiri, Arista, Lal, Dharmesh Kumar, Lám, Judit, Lan, Qing, Landires, Iván, Larijani, Bagher, Lasrado, Savita, Lau, Jerrald, Lauriola, Paolo, Ledda, Caterina, Lee, Sang-woong, Lee, Shaun Wen Huey, Lee, Wei-chen, Lee, Yeong Yeh, Lee, Yo Han, Legesse, Samson Mideksa, Leigh, James, Leong, Elvynna, Li, Ming-chieh, Lim, Stephen S, Liu, Gang, Liu, Jue, Lo, Chun-han, Lohiya, Ayush, Lopukhov, Platon D, Lorenzovici, László, Lotfi, Mojgan, Loureiro, Joana A, Lunevicius, Raimundas, Madadizadeh, Farzan, Mafi, Ahmad R, Magdeldin, Sameh, Mahjoub, Soleiman, Mahmoodpoor, Ata, Mahmoudi, Morteza, Mahmoudimanesh, Marzieh, Mahumud, Rashidul Alam, Majeed, Azeem, Majidpoor, Jamal, Makki, Alaa, Makris, Konstantinos Christos, Malakan Rad, Elaheh, Malekpour, Mohammad-reza, Malekzadeh, Reza, Malik, Ahmad Azam, Mallhi, Tauqeer Hussain, Mallya, Sneha Deepak, Mamun, Mohammed A, Manda, Ana Laura, Mansour-ghanaei, Fariborz, Mansouri, Borhan, Mansournia, Mohammad Ali, Mantovani, Lorenzo Giovanni, Martini, Santi, Martorell, Miquel, Masoudi, Sahar, Masoumi, Seyedeh Zahra, Matei, Clara N, Mathews, Elezebeth, Mathur, Manu Raj, Mathur, Vasundhara, Mckee, Martin, Meena, Jitendra Kumar, Mehmood, Khalid, Mehrabi Nasab, Entezar, Mehrotra, Ravi, Melese, Addisu, Mendoza, Walter, Menezes, Ritesh G, Mengesha, Sisay Derso, Mensah, Laverne G, Mentis, Alexios-fotios A, Mera-mamián, Andry Yasmid Mera, Meretoja, Tuomo J, Merid, Mehari Woldemariam, Mersha, Amanual Getnet, Meselu, Belsity Temesgen, Meshkat, Mahboobeh, Mestrovic, Tomislav, Miao Jonasson, Junmei, Miazgowski, Tomasz, Michalek, Irmina Maria, Mijena, Gelana Fekadu Worku, Miller, Ted R, Mir, Shabir Ahmad, Mirinezhad, Seyed Kazem, Mirmoeeni, Seyyedmohammadsadeq, Mirza-aghazadeh-attari, Mohammad, Mirzaei, Hamed, Mirzaei, Hamid Reza, Misganaw, Abay Sisay, Misra, Sanjeev, Mohammad, Karzan Abdulmuhsin, Mohammadi, Esmaeil, Mohammadi, Mokhtar, Mohammadian-hafshejani, Abdollah, Mohammadpourhodki, Reza, Mohammed, Arif, Mohammed, Shafiu, Mohan, Syam, Mohseni, Mohammad, Moka, Nagabhishek, Mokdad, Ali H, Molassiotis, Alex, Molokhia, Mariam, Momenzadeh, Kaveh, Momtazmanesh, Sara, Monasta, Lorenzo, Mons, Ute, Montasir, Ahmed Al, Montazeri, Fateme, Montero, Arnulfo, Moosavi, Mohammad Amin, Moradi, Abdolvahab, Moradi, Yousef, Moradi Sarabi, Mostafa, Moraga, Paula, Morawska, Lidia, Morrison, Shane Douglas, Morze, Jakub, Mosapour, Abbas, Mostafavi, Ebrahim, Mousavi, Seyyed Meysam, Mousavi Isfahani, Haleh, Mousavi Khaneghah, Amin, Mpundu-kaambwa, Christine, Mubarik, Sumaira, Mulita, Francesk, Munblit, Daniel, Munro, Sandra B, Murillo-zamora, Efrén, Musa, Jonah, Nabhan, Ashraf F, Nagarajan, Ahamarshan Jayaraman, Nagaraju, Shankar Prasad, Nagel, Gabriele, Naghipour, Mohammadreza, Naimzada, Mukhammad David, Nair, Tapas Sadasivan, Naqvi, Atta Abbas, Narasimha Swamy, Sreenivas, Narayana, Aparna Ichalangod, Nassereldine, Hasan, Natto, Zuhair S, Nayak, Biswa Prakash, Ndejjo, Rawlance, Nduaguba, Sabina Onyinye, Negash, Wogene Wogene, Nejadghaderi, Seyed Aria, Nejati, Kazem, Neupane Kandel, Sandhya, Nguyen, Huy Van Nguyen, Niazi, Robina Khan, Noor, Nurulamin M, Noori, Maryam, Noroozi, Nafise, Nouraei, Hasti, Nowroozi, Ali, Nuñez-samudio, Virginia, Nzoputam, Chimezie Igwegbe, Nzoputam, Ogochukwu Janet, Oancea, Bogdan, Odukoya, Oluwakemi Ololade, Oghenetega, Onome Bright, Ogunsakin, Ropo Ebenezer, Oguntade, Ayodipupo Sikiru, Oh, In-hwan, Okati-aliabad, Hassan, Okekunle, Akinkunmi Paul, Olagunju, Andrew T, Olagunju, Tinuke O, Olakunde, Babayemi Oluwaseun, Olufadewa, Isaac Iyinoluwa, Omer, Emad, Omonisi, Abidemi E Emmanuel, Ong, Sokking, Onwujekwe, Obinna E, Orru, Hans, Otstavnov, Stanislav S, Oulhaj, Abderrahim, Oumer, Bilcha, Owopetu, Oluwatomi Funbi, Oyinloye, Babatunji Emmanuel, P A, Mahesh, Padron-monedero, Alicia, Padubidri, Jagadish Rao, Pakbin, Babak, Pakshir, Keyvan, Pakzad, Reza, Palicz, Tamás, Pana, Adrian, Pandey, Anamika, Pandey, Ashok, Pant, Suman, Pardhan, Shahina, Park, Eun-cheol, Park, Eun-kee, Park, Seoyeon, Patel, Jay, Pati, Siddhartha, Paudel, Rajan, Paudel, Uttam, Paun, Mihaela, Pazoki Toroudi, Hamidreza, Peng, Minjin, Pereira, Jeevan, Pereira, Renato B, Perna, Simone, Perumalsamy, Navaraj, Pestell, Richard G, Pezzani, Raffaele, Piccinelli, Cristiano, Pillay, Julian David, Piracha, Zahra Zahid, Pischon, Tobias, Postma, Maarten J, Pourabhari Langroudi, Ashkan, Pourshams, Akram, Pourtaheri, Naeimeh, Prashant, Akila, Qadir, Mirza Muhammad Fahd, Quazi Syed, Zahiruddin, Rabiee, Mohammad, Rabiee, Navid, Radfar, Amir, Radhakrishnan, Raghu Anekal, Radhakrishnan, Venkatraman, Raeisi, Mojtaba, Rafiee, Ata, Rafiei, Alireza, Raheem, Nasiru, Rahim, Fakher, Rahman, Md Obaidur, Rahman, Mosiur, Rahman, Muhammad Aziz, Rahmani, Amir Masoud, Rahmani, Shayan, Rahmanian, Vahid, Rajai, Nazanin, Rajesh, Aashish, Ram, Pradhum, Ramezanzadeh, Kiana, Rana, Juwel, Ranabhat, Kamal, Ranasinghe, Priyanga, Rao, Chythra R, Rao, Sowmya J, Rashedi, Sina, Rashidi, Amirfarzan, Rashidi, Mahsa, Rashidi, Mohammad-mahdi, Ratan, Zubair Ahmed, Rawaf, David Laith, Rawaf, Salman, Rawal, Lal, Rawassizadeh, Reza, Razeghinia, Mohammad Sadegh, Rehman, Ashfaq Ur, Rehman, Inayat Ur, Reitsma, Marissa B, Renzaho, Andre M N, Rezaei, Maryam, Rezaei, Nazila, Rezaei, Negar, Rezaei, Nima, Rezaei, Saeid, Rezaeian, Mohsen, Rezapour, Aziz, Riad, Abanoub, Rikhtegar, Reza, Rios-blancas, Maria, Roberts, Thomas J, Rohloff, Peter, Romero-rodríguez, Esperanza, Roshandel, Gholamreza, Rwegerera, Godfrey M, S, Manjula, Saber-ayad, Maha Mohamed, Saberzadeh-ardestani, Bahar, Sabour, Siamak, Saddik, Basema, Sadeghi, Erfan, Saeb, Mohammad Reza, Saeed, Umar, Safaei, Mohsen, Safary, Azam, Sahebazzamani, Maryam, Sahebkar, Amirhossein, Sahoo, Harihar, Sajid, Mirza Rizwan, Salari, Hedayat, Salehi, Sana, Salem, Marwa Rashad, Salimzadeh, Hamideh, Samodra, Yoseph Leonardo, Samy, Abdallah M, Sanabria, Juan, Sankararaman, Senthilkumar, Sanmarchi, Francesco, Santric-milicevic, Milena M, Saqib, Muhammad Arif Nadeem, Sarveazad, Arash, Sarvi, Fatemeh, Sathian, Brijesh, Satpathy, Maheswar, Sayegh, Nicolas, Schneider, Ione Jayce Ceola, Schwarzinger, Michaël, Šekerija, Mario, Senthilkumaran, Subramanian, Sepanlou, Sadaf G, Seylani, Allen, Seyoum, Kenbon, Sha, Feng, Shafaat, 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Naohiro, Younis, Mustafa Z, Yousefi, Zabihollah, Yousefian, Fatemeh, Yu, Chuanhua, Yu, Yong, Yunusa, Ismaeel, Zahir, Mazyar, Zaki, Nazar, Zaman, Burhan Abdullah, Zangiabadian, Moein, Zare, Fariba, Zare, Iman, Zareshahrabadi, Zahra, Zarrintan, Armin, Zastrozhin, Mikhail Sergeevich, Zeineddine, Mohammad A, Zhang, Dongyu, Zhang, Jianrong, Zhang, Yunquan, Zhang, Zhi-jiang, Zhou, Linghui, Zodpey, Sanjay, Zoladl, Mohammad, Vos, Theo, Hay, Simon I, Force, Lisa M, Murray, Christopher J L, NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), and DCM - Departamento de Ciência dos Materiais

Subjects
SDG 3 - Good Health and Well-being
Abstract

Funding: J A Loureiro reports support for the present manuscript from Scientific Employment Stimulus (FCT; CEECINST/00049/2018) as support to their salary and from UIDB/00511/2020 of the LEPABE, funded by national funds through the FCT/MCTES (PIDDAC) as research support. BACKGROUND: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. METHODS: The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk-outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. FINDINGS: Globally, in 2019, the risk factors included in this analysis accounted for 4·45 million (95% uncertainty interval 4·01-4·94) deaths and 105 million (95·0-116) DALYs for both sexes combined, representing 44·4% (41·3-48·4) of all cancer deaths and 42·0% (39·1-45·6) of all DALYs. There were 2·88 million (2·60-3·18) risk-attributable cancer deaths in males (50·6% [47·8-54·1] of all male cancer deaths) and 1·58 million (1·36-1·84) risk-attributable cancer deaths in females (36·3% [32·5-41·3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20·4% (12·6-28·4) and DALYs by 16·8% (8·8-25·0), with the greatest percentage increase in metabolic risks (34·7% [27·9-42·8] and 33·3% [25·8-42·0]). INTERPRETATION: The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden. FUNDING: Bill & Melinda Gates Foundation. publishersversion published

Published
2022

50. PD22-08 RISK OF RADIATION-INDUCED FISTULA IS LOW AND MAY BE INCREASED IN PATIENTS WITH PRIOR PELVIC RADIATION OR CONCURRENT CHEMOTHERAPY: A SYSTEMATIC REVIEW AND META-ANALYSIS

Author

Sadighian, Michael, primary, Hakam, Nizar, additional, Amend, Gregory, additional, Shaw, Nathan, additional, Tahir, Peggy, additional, Allen, Isabel Elaine, additional, Nabavizadeh, Behnam, additional, Holler, Jordan, additional, Shibley, William, additional, Li, Kevin, additional, Abbasi, Behzad, additional, Bell, Alexander, additional, Mohamad, Osama, additional, and Breyer, Benjamin, additional

Published
2022
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