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1. Single-exposure elemental differentiation and texture-sensitive phase-retrieval imaging with a neutron counting micro-channel plate detector

Author

Arhatari, Benedicta D., Paganin, David M., Kirkwood, Henry, Tremsin, Anton S., Gureyev, Timur E., Korsunsky, Alexander M., Kockelmann, Winfried, Hofmann, Felix, Huwald, Eric, Zhang, Shu-Yan, Kelleher, Joe, and Abbey, Brian

Subjects
Condensed Matter - Materials Science, Electrical Engineering and Systems Science - Image and Video Processing, Physics - Optics
Abstract

Micro-channel plate (MCP) detectors, when used at pulsed-neutron-source instruments, offer the possibility of high spatial resolution and high contrast imaging with pixel-level spectroscopic information. Here we demonstrate the possibility of multimodal analysis including total neutron cross-section spectra measurements, quantitative material differentiation imaging and texture-sensitive in-line phase imaging, from a single exposure using an MCP detector. This multimodal approach operates in full-field imaging mode, with the neutron transmission spectra acquired at each individual detector pixel. Due to the polychromatic nature of the beam and spectroscopic resolving capability of the detector, no energy scanning is required. Good agreement with the library reference data is demonstrated for neutron cross-section spectra measurements. Two different images corresponding to two selected energy bandwidths are used for elemental differentiation imaging. Moreover, the presence of changes in texture, i.e., preferred grain orientation, in the sample is identified from our phase-retrieval imaging results., Comment: Revised manuscript resubmitted to Physical Review A

Published
2023
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3. Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers

Author

Holmes, Susannah, Kirkwood, Henry J, Bean, Richard, Giewekemeyer, Klaus, Martin, Andrew V, Hadian-Jazi, Marjan, Wiedorn, Max O, Oberthür, Dominik, Marman, Hugh, Adriano, Luigi, Al-Qudami, Nasser, Bajt, Saša, Barák, Imrich, Bari, Sadia, Bielecki, Johan, Brockhauser, Sandor, Coleman, Mathew A, Cruz-Mazo, Francisco, Danilevski, Cyril, Dörner, Katerina, Gañán-Calvo, Alfonso M, Graceffa, Rita, Fanghor, Hans, Heymann, Michael, Frank, Matthias, Kaukher, Alexander, Kim, Yoonhee, Kobe, Bostjan, Knoška, Juraj, Laurus, Torsten, Letrun, Romain, Maia, Luis, Messerschmidt, Marc, Metz, Markus, Michelat, Thomas, Mills, Grant, Molodtsov, Serguei, Monteiro, Diana CF, Morgan, Andrew J, Münnich, Astrid, Peña Murillo, Gisel E, Previtali, Gianpietro, Round, Adam, Sato, Tokushi, Schubert, Robin, Schulz, Joachim, Shelby, Megan, Seuring, Carolin, Sellberg, Jonas A, Sikorski, Marcin, Silenzi, Alessandro, Stern, Stephan, Sztuk-Dambietz, Jola, Szuba, Janusz, Trebbin, Martin, Vagovic, Patrick, Ve, Thomas, Weinhausen, Britta, Wrona, Krzysztof, Xavier, Paul Lourdu, Xu, Chen, Yefanov, Oleksandr, Nugent, Keith A, Chapman, Henry N, Mancuso, Adrian P, Barty, Anton, Abbey, Brian, and Darmanin, Connie

Subjects
Inorganic Chemistry, Chemical Sciences, Physical Sciences, Biological Sciences, Crystallography, X-Ray, Electrons, Lasers, Radiography, X-Rays
Abstract

The European X-ray Free Electron Laser (XFEL) and Linac Coherent Light Source (LCLS) II are extremely intense sources of X-rays capable of generating Serial Femtosecond Crystallography (SFX) data at megahertz (MHz) repetition rates. Previous work has shown that it is possible to use consecutive X-ray pulses to collect diffraction patterns from individual crystals. Here, we exploit the MHz pulse structure of the European XFEL to obtain two complete datasets from the same lysozyme crystal, first hit and the second hit, before it exits the beam. The two datasets, separated by

Published
2022

5. Diffraction data from aerosolized Coliphage PR772 virus particles imaged with the Linac Coherent Light Source

Author

Li, Haoyuan, Nazari, Reza, Abbey, Brian, Alvarez, Roberto, Aquila, Andrew, Ayyer, Kartik, Barty, Anton, Berntsen, Peter, Bielecki, Johan, Pietrini, Alberto, Bucher, Maximilian, Carini, Gabriella, Chapman, Henry N, Contreras, Alice, Daurer, Benedikt J, DeMirci, Hasan, Flűckiger, Leonie, Frank, Matthias, Hajdu, Janos, Hantke, Max F, Hogue, Brenda G, Hosseinizadeh, Ahmad, Hunter, Mark S, Jönsson, H Olof, Kirian, Richard A, Kurta, Ruslan P, Loh, Duane, Maia, Filipe RNC, Mancuso, Adrian P, Morgan, Andrew J, McFadden, Matthew, Muehlig, Kerstin, Munke, Anna, Reddy, Hemanth Kumar Narayana, Nettelblad, Carl, Ourmazd, Abbas, Rose, Max, Schwander, Peter, Marvin Seibert, M, Sellberg, Jonas A, Sierra, Raymond G, Sun, Zhibin, Svenda, Martin, Vartanyants, Ivan A, Walter, Peter, Westphal, Daniel, Williams, Garth, Xavier, P Lourdu, Yoon, Chun Hong, and Zaare, Sahba

Subjects
Chemical Sciences, Synchrotrons and Accelerators, Physical Sciences, Coliphages, Lasers, Particle Accelerators, Virion, X-Ray Diffraction
Abstract

Single Particle Imaging (SPI) with intense coherent X-ray pulses from X-ray free-electron lasers (XFELs) has the potential to produce molecular structures without the need for crystallization or freezing. Here we present a dataset of 285,944 diffraction patterns from aerosolized Coliphage PR772 virus particles injected into the femtosecond X-ray pulses of the Linac Coherent Light Source (LCLS). Additional exposures with background information are also deposited. The diffraction data were collected at the Atomic, Molecular and Optical Science Instrument (AMO) of the LCLS in 4 experimental beam times during a period of four years. The photon energy was either 1.2 or 1.7 keV and the pulse energy was between 2 and 4 mJ in a focal spot of about 1.3 μm x 1.7 μm full width at half maximum (FWHM). The X-ray laser pulses captured the particles in random orientations. The data offer insight into aerosolised virus particles in the gas phase, contain information relevant to improving experimental parameters, and provide a basis for developing algorithms for image analysis and reconstruction.

Published
2020

9. Megahertz serial crystallography

Author

Wiedorn, Max O, Oberthür, Dominik, Bean, Richard, Schubert, Robin, Werner, Nadine, Abbey, Brian, Aepfelbacher, Martin, Adriano, Luigi, Allahgholi, Aschkan, Al-Qudami, Nasser, Andreasson, Jakob, Aplin, Steve, Awel, Salah, Ayyer, Kartik, Bajt, Saša, Barák, Imrich, Bari, Sadia, Bielecki, Johan, Botha, Sabine, Boukhelef, Djelloul, Brehm, Wolfgang, Brockhauser, Sandor, Cheviakov, Igor, Coleman, Matthew A, Cruz-Mazo, Francisco, Danilevski, Cyril, Darmanin, Connie, Doak, R Bruce, Domaracky, Martin, Dörner, Katerina, Du, Yang, Fangohr, Hans, Fleckenstein, Holger, Frank, Matthias, Fromme, Petra, Gañán-Calvo, Alfonso M, Gevorkov, Yaroslav, Giewekemeyer, Klaus, Ginn, Helen Mary, Graafsma, Heinz, Graceffa, Rita, Greiffenberg, Dominic, Gumprecht, Lars, Göttlicher, Peter, Hajdu, Janos, Hauf, Steffen, Heymann, Michael, Holmes, Susannah, Horke, Daniel A, Hunter, Mark S, Imlau, Siegfried, Kaukher, Alexander, Kim, Yoonhee, Klyuev, Alexander, Knoška, Juraj, Kobe, Bostjan, Kuhn, Manuela, Kupitz, Christopher, Küpper, Jochen, Lahey-Rudolph, Janine Mia, Laurus, Torsten, Le Cong, Karoline, Letrun, Romain, Xavier, P Lourdu, Maia, Luis, Maia, Filipe RNC, Mariani, Valerio, Messerschmidt, Marc, Metz, Markus, Mezza, Davide, Michelat, Thomas, Mills, Grant, Monteiro, Diana CF, Morgan, Andrew, Mühlig, Kerstin, Munke, Anna, Münnich, Astrid, Nette, Julia, Nugent, Keith A, Nuguid, Theresa, Orville, Allen M, Pandey, Suraj, Pena, Gisel, Villanueva-Perez, Pablo, Poehlsen, Jennifer, Previtali, Gianpietro, Redecke, Lars, Riekehr, Winnie Maria, Rohde, Holger, Round, Adam, Safenreiter, Tatiana, Sarrou, Iosifina, Sato, Tokushi, Schmidt, Marius, Schmitt, Bernd, Schönherr, Robert, Schulz, Joachim, Sellberg, Jonas A, Seibert, M Marvin, and Seuring, Carolin

Subjects
Biochemistry and Cell Biology, Chemical Sciences, Biological Sciences
Abstract

The new European X-ray Free-Electron Laser is the first X-ray free-electron laser capable of delivering X-ray pulses with a megahertz inter-pulse spacing, more than four orders of magnitude higher than previously possible. However, to date, it has been unclear whether it would indeed be possible to measure high-quality diffraction data at megahertz pulse repetition rates. Here, we show that high-quality structures can indeed be obtained using currently available operating conditions at the European XFEL. We present two complete data sets, one from the well-known model system lysozyme and the other from a so far unknown complex of a β-lactamase from K. pneumoniae involved in antibiotic resistance. This result opens up megahertz serial femtosecond crystallography (SFX) as a tool for reliable structure determination, substrate screening and the efficient measurement of the evolution and dynamics of molecular structures using megahertz repetition rate pulses available at this new class of X-ray laser source.

Published
2018

10. Coherent X-ray measurements of ion-implantation-induced lattice strains in nano-crystals

Author

Hofmann, Felix, Tarleton, Edmund, Harder, Ross J., Phillips, Nicholas W., Clark, Jesse N., Robinson, Ian K., Abbey, Brian, Liu, Wenjun, and Beck, Christian E.

Subjects
Condensed Matter - Materials Science
Abstract

Focussed Ion Beam (FIB) milling is a mainstay of nano-scale machining. By manipulating a tightly focussed beam of energetic ions, often gallium (Ga+), FIB can sculpt nanostructures via localised sputtering. This ability to cut solid matter on the nano-scale has revolutionised sample preparation across the life-, earth- and materials sciences. For example FIB is central to microchip prototyping, 3D material analysis, targeted electron microscopy sample extraction and the nanotechnology behind size-dependent material properties. Despite its widespread usage, detailed understanding of the functional consequences of FIB-induced structural damage, intrinsic to the technique, remains elusive. Here, we present nano-scale measurements of three-dimensional, FIB-induced lattice strains, probed using Bragg Coherent X-ray Diffraction Imaging (BCDI). We observe that even low gallium ion doses, typical of FIB imaging, cause substantial lattice distortions. At higher doses, extended self-organised defect structures appear, giving rise to stresses far in excess of the bulk yield limit. Combined with detailed numerical calculations, these observations provide fundamental insight into the nature of the damage created and the structural instabilities that lead to a surprisingly inhomogeneous morphology., Comment: 35 pages total, 12 figures total. Main text 16 pages 3 figures. Supplementary information 19 pages 9 figures

Published
2016

12. Roadmap on Label‐Free Super‐Resolution Imaging (Laser Photonics Rev. 17(12)/2023)

Author

Astratov, Vasily N., primary, Sahel, Yair Ben, additional, Eldar, Yonina C., additional, Huang, Luzhe, additional, Ozcan, Aydogan, additional, Zheludev, Nikolay, additional, Zhao, Junxiang, additional, Burns, Zachary, additional, Liu, Zhaowei, additional, Narimanov, Evgenii, additional, Goswami, Neha, additional, Popescu, Gabriel, additional, Pfitzner, Emanuel, additional, Kukura, Philipp, additional, Hsiao, Yi‐Teng, additional, Hsieh, Chia‐Lung, additional, Abbey, Brian, additional, Diaspro, Alberto, additional, LeGratiet, Aymeric, additional, Bianchini, Paolo, additional, Shaked, Natan T., additional, Simon, Bertrand, additional, Verrier, Nicolas, additional, Debailleul, Matthieu, additional, Haeberlé, Olivier, additional, Wang, Sheng, additional, Liu, Mengkun, additional, Bai, Yeran, additional, Cheng, Ji‐Xin, additional, Kariman, Behjat S., additional, Fujita, Katsumasa, additional, Sinvani, Moshe, additional, Zalevsky, Zeev, additional, Li, Xiangping, additional, Huang, Guan‐Jie, additional, Chu, Shi‐Wei, additional, Tzang, Omer, additional, Hershkovitz, Dror, additional, Cheshnovsky, Ori, additional, Huttunen, Mikko J., additional, Stanciu, Stefan G., additional, Smolyaninova, Vera N., additional, Smolyaninov, Igor I., additional, Leonhardt, Ulf, additional, Sahebdivan, Sahar, additional, Wang, Zengbo, additional, Luk'yanchuk, Boris, additional, Wu, Limin, additional, Maslov, Alexey V., additional, Jin, Boya, additional, Simovski, Constantin R., additional, Perrin, Stephane, additional, Montgomery, Paul, additional, and Lecler, Sylvain, additional

Published
2023
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14. MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography

Author

Clabbers, Max T. B., Holmes, Susannah, Muusse, Timothy W., Vajjhala, Parimala R., Thygesen, Sara J., Malde, Alpeshkumar K., Hunter, Dominic J. B., Croll, Tristan I., Flueckiger, Leonie, Nanson, Jeffrey D., Rahaman, Md. Habibur, Aquila, Andrew, Hunter, Mark S., Liang, Mengning, Yoon, Chun Hong, Zhao, Jingjing, Zatsepin, Nadia A., Abbey, Brian, Sierecki, Emma, Gambin, Yann, Stacey, Katryn J., Darmanin, Connie, Kobe, Bostjan, Xu, Hongyi, and Ve, Thomas

Published
2021
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15. Femtosecond X-ray Laser induced transient electronic phase change observed in fullerene C60

Author

Abbey, Brian, Dilanian, Ruben A., Darmanin, Connie, Ryan, Rebecca A., Putkunz, Corey T., Martin, Andrew V., Streltsov, Victor, Jones, Michael W. M., Gaffney, Naylyn, Hofmann, Felix, Williams, Garth J., Boutet, Sebastian, Messerschmidt, Marc, Siebert, M. Marvin, Williams, Sophie, Curwood, Evan, Balaur, Eugeniu, Peele, Andrew G., Nugent, Keith A., and Quiney, Harry M.

Subjects
Condensed Matter - Materials Science, Physics - Optics
Abstract

X-ray Free-Electron Lasers (XFELs) deliver X-ray pulses with a coherent flux that is approximately eight orders of magnitude greater than that available from a modern third generation synchrotron source. The power density in an XFEL pulse may be so high that it can modify the electronic properties of a sample on a femtosecond timescale. Exploration of the interaction of intense coherent X-ray pulses and matter is of both intrinsic scientific interest, and of critical importance to the interpretation of experiments that probe the structures of materials using high-brightness femtosecond XFEL pulses. In this letter, we report observations of the diffraction of an extremely intense 32 fs nanofocused X-ray pulses by a powder sample of crystalline C60. We find that the diffraction pattern at the highest available incident power exhibits significant structural signatures that are absent in data obtained at both third-generation synchrotron sources or from XFEL sources operating at low output power. These signatures are consistent with a highly ordered structure that does not correspond with any previously known phase of crystalline C60. We argue that these data indicate the formation of a transient phase that is formed by a dynamic electronic distortion induced by inner-shell ionisation of at least one carbon atom in each C60 molecule., Comment: 9 pages, 3 figures

Published
2012

22. Optical chemical barcoding based on polarization controlled plasmonic nanopixels

Author

Langley, Daniel, Balaur, Eugeniu, Hwang, Y, Sadatnajafi, Catherine, and Abbey, Brian

Subjects
Uncategorized
Abstract

Plasmonic devices offer the possibility of passively detecting changes in local chemistry that opens up a wide range of applications from molecular sensing to monitoring water quality. Conventional plasmonics have previously shown great promise as nanoscale chemical sensors through detection of small variations in the local refractive index (RI). The motivation behind using plasmonics for these applications includes the fact that detection is entirely passive and the devices themselves can be readily miniaturized. Previously, a lack of any control over the output of these devices, has fundamentally limited their application to chemicals which produce clearly identifiable resonances within the range of detection. Here it is demonstrated that microfluidic devices, incorporating polarization-controlled plasmonic nanopixels, allow the device response to be tuned to the particular analyte of interest, anywhere within the visible spectrum. This dramatically increases the effective dynamic range and allows local variations in RI to be perceived directly as color changes by the human eye. Active control over the output of the device also enables clear differentiation between a number of different analytes, paving the way for plasmonics to be used for a wide range of real-world chemical sensing applications.

Published
2023
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24. Imaging transient melting of a nanocrystal using an X-ray laser

Author

Clark, Jesse N., Beitra, Loren, Xiong, Gang, Fritz, David M., Lemke, Henrik T., Zhu, Diling, Chollet, Matthieu, Williams, Garth J., Messerschmidt, Marc M., Abbey, Brian, Harder, Ross J., Korsunsky, Alexander M., Wark, Justin S., Reis, David A., and Robinson, Ian K.

Published
2015

25. Towards real-time analysis of liquid jet alignment in serial femtosecond crystallography

Author

Patel, Jaydeep, primary, Round, Adam, additional, Bielecki, Johan, additional, Doerner, Katerina, additional, Kirkwood, Henry, additional, Letrun, Romain, additional, Schulz, Joachim, additional, Sikorski, Marcin, additional, Vakili, Mohammad, additional, de Wijn, Raphael, additional, Peele, Andrew, additional, Mancuso, Adrian P., additional, and Abbey, Brian, additional

Published
2022
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27. Shot-to-shot two-dimensional photon intensity diagnostics within megahertz pulse-trains at the European XFEL

Author

Guest, Trey W., primary, Bean, Richard, additional, Bielecki, Johan, additional, Birnsteinova, Sarlota, additional, Geloni, Gianluca, additional, Guetg, Marc, additional, Kammering, Raimund, additional, Kirkwood, Henry J., additional, Koch, Andreas, additional, Paganin, David M., additional, van Riessen, Grant, additional, Vagovič, Patrik, additional, de Wijn, Raphael, additional, Mancuso, Adrian P., additional, and Abbey, Brian, additional

Published
2022
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28. Colorimetric histology using plasmonically active microscope slides

Author

Balaur, Eugeniu, Toole, Sandra O', Spurling, Alex J, Mann, G Bruce, Yeo, Belinda, Harvey, Kate, Sadatnajafi, Catherine, Hanssen, Eric, Orian, Jacqueline, Nugent, Keith, Parker, Belinda, and Abbey, Brian

Subjects
Uncategorized
Abstract

The human eye can distinguish as many as 10,000 different colours but is far less sensitive to variations in intensity1, meaning that colour is highly desirable when interpreting images. However, most biological samples are essentially transparent, and nearly invisible when viewed using a standard optical microscope2. It is therefore highly desirable to be able to produce coloured images without needing to add any stains or dyes, which can alter the sample properties. Here we demonstrate that colorimetric histology images can be generated using full-sized plasmonically active microscope slides. These slides translate subtle changes in the dielectric constant into striking colour contrast when samples are placed upon them. We demonstrate the biomedical potential of this technique, which we term histoplasmonics, by distinguishing neoplastic cells from normal breast epithelium during the earliest stages of tumorigenesis in the mouse MMTV-PyMT mammary tumour model. We then apply this method to human diagnostic tissue and validate its utility in distinguishing normal epithelium, usual ductal hyperplasia, and early-stage breast cancer (ductal carcinoma in situ). The colorimetric output of the image pixels is compared to conventional histopathology. The results we report here support the hypothesis that histoplasmonics can be used as a novel alternative or adjunct to general staining. The widespread availability of this technique and its incorporation into standard laboratory workflows may prove transformative for applications extending well beyond tissue diagnostics. This work also highlights opportunities for improvements to digital pathology that have yet to be explored.

Published
2022
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29. Observations of phase changes in monoolein during high viscous injection

Author

Wells, Daniel, Berntsen, Peter, Balaur, Eugeniu, Kewish, Cameron, Adams, Patrick, Boutet, Sebastien, Broomhall, Hayden, Caleman, Carl, Christofferson, Andrew, Conn, Charlotte E, Dahlqvist, Caroline, Flueckiger, Leonie, Roque, Francisco Gian, Greaves, Tamar, Hejazian, Majid, Hunter, Mark, Hadian Jazi, Marjan, Jonsson, H Olof, Pathirannahalage, Sachini Kadaoluwa, Kirian, Richard, Kozlov, Alex, Kurta, Ruslan, Marman, Hugh, Mendez, Derek, Morgan, Andrew, Nugent, Keith, Oberthuer, Dominik, Quinney, Harry, Reinhardt, Juliane, Saha, Sumitra, Selberg, Jonas, Sierra, Raymond, Wiedorn, Max, Abbey, Brian, Andrew, Martin, and Darmanin, Connie

Subjects
29999 Physical Sciences not elsewhere classified, FOS: Physical sciences
Abstract

Serial crystallography of membrane proteins often employs high-viscosity injectors (HVIs) to deliver micrometre-sized crystals to the X-ray beam. Typically, the carrier medium is a lipidic cubic phase (LCP) media, which can also be used to nucleate and grow the crystals. However, despite the fact that the LCP is widely used with HVIs, the potential impact of the injection process on the LCP structure has not been reported and hence is not yet well understood. The self-assembled structure of the LCP can be affected by pressure, dehydration and temperature changes, all of which occur during continuous flow injection. These changes to the LCP structure may in turn impact the results of X-ray diffraction measurements from membrane protein crystals. To investigate the influence of HVIs on the structure of the LCP we conducted a study of the phase changes in monoolein/water and monoolein/buffer mixtures during continuous flow injection, at both atmospheric pressure and under vacuum. The reservoir pressure in the HVI was tracked to determine if there is any correlation with the phase behaviour of the LCP. The results indicated that, even though the reservoir pressure underwent (at times) significant variation, this did not appear to correlate with observed phase changes in the sample stream or correspond to shifts in the LCP lattice parameter. During vacuum injection, there was a three-way coexistence of the gyroid cubic phase, diamond cubic phase and lamellar phase. During injection at atmospheric pressure, the coexistence of a cubic phase and lamellar phase in the monoolein/water mixtures was also observed. The degree to which the lamellar phase is formed was found to be strongly dependent on the co-flowing gas conditions used to stabilize the LCP stream. A combination of laboratory-based optical polarization microscopy and simulation studies was used to investigate these observations.

Published
2022
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33. Observations of phase changes in monoolein during high viscous injection

Author

Wells, Daniel J., primary, Berntsen, Peter, additional, Balaur, Eugeniu, additional, Kewish, Cameron M., additional, Adams, Patrick, additional, Aquila, Andrew, additional, Binns, Jack, additional, Boutet, Sébastien, additional, Broomhall, Hayden, additional, Caleman, Carl, additional, Christofferson, Andrew, additional, Conn, Charlotte E., additional, Dahlqvist, Caroline, additional, Flueckiger, Leonie, additional, Gian Roque, Francisco, additional, Greaves, Tamar L., additional, Hejazian, Majid, additional, Hunter, Mark, additional, Hadian Jazi, Marjan, additional, Jönsson, H. Olof, additional, Pathirannahalage, Sachini Kadaoluwa, additional, Kirian, Richard A., additional, Kozlov, Alex, additional, Kurta, Ruslan P., additional, Marman, Hugh, additional, Mendez, Derek, additional, Morgan, Andrew, additional, Nugent, Keith, additional, Oberthuer, Dominik, additional, Quiney, Harry, additional, Reinhardt, Juliane, additional, Saha, Saumitra, additional, Sellberg, Jonas A., additional, Sierra, Raymond, additional, Wiedorn, Max, additional, Abbey, Brian, additional, Martin, Andrew V., additional, and Darmanin, Connie, additional

Published
2022
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35. Preferred orientation and its effects on intensity-correlation measurements

Author

Binns, Jack, primary, Darmanin, Connie, additional, Kewish, Cameron M., additional, Pathirannahalge, Sachini Kadaoluwa, additional, Berntsen, Peter, additional, Adams, Patrick L. R., additional, Paporakis, Stefan, additional, Wells, Daniel, additional, Roque, Francisco Gian, additional, Abbey, Brian, additional, Bryant, Gary, additional, Conn, Charlotte E., additional, Mudie, Stephen T., additional, Hawley, Adrian M., additional, Ryan, Timothy M., additional, Greaves, Tamar L., additional, and Martin, Andrew V., additional

Published
2022
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38. Rachel's Radical Gospel: A Marxist Critique.

Author

Abbey, Brian and Ashenden, Dean

Abstract

This paper presents a Marxist reply to a philosophical discourse on the role of the "progressive" teacher in the education of children. The position under attack is that teachers themselves, no matter how progressive, are a part of the social hierarchy and impose middle class values on children, thus perpetuating the system. They are, in brief, one of the "enemy" to the true radical. The argument is made that it is desirable to join progressive teachers with marxists through active trade unions, using the best potential of all to change the system. An association of the practice-oriented progressive teacher with the theory-oriented socialist will help resolve the gap of understanding between the two and aid in the development of a socialist, revolutionary, educational praxis. (JD)

Published
1977

40. Student Housing: A Retrospect and Some Prospects.

Author

Abbey, Brian

Abstract

A discussion of Australian college housing reviews some major studies, chronicles the development and current provision of college housing, examines some supply and financing issues, and examines the role of government policy. It is concluded that college housing is a significant part of the student's educational experience. (MSE)

Published
1994

41. Data reduction for serial crystallography using a robust peak finder

Author

Hadian-Jazi, Marjan, primary, Sadri, Alireza, additional, Barty, Anton, additional, Yefanov, Oleksandr, additional, Galchenkova, Marina, additional, Oberthuer, Dominik, additional, Komadina, Dana, additional, Brehm, Wolfgang, additional, Kirkwood, Henry, additional, Mills, Grant, additional, de Wijn, Raphael, additional, Letrun, Romain, additional, Kloos, Marco, additional, Vakili, Mohammad, additional, Gelisio, Luca, additional, Darmanin, Connie, additional, Mancuso, Adrian P., additional, Chapman, Henry N., additional, and Abbey, Brian, additional

Published
2021
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42. MyD88 TIR domain higher-order assembly interactions revealed by serial femtosecond crystallography

Author

Holmes, Susannah, primary, Clabbers, Max T. B., additional, Muusse, Timothy W., additional, Vajjhala, Parimala R., additional, Thygesen, Sara J., additional, Malde, Alpeshkumar K., additional, Hunter, Dominic J. B., additional, Croll, Tristan I., additional, Flueckiger, Leonie, additional, Nanson, Jeffrey D., additional, Rahaman, Md. Habibur, additional, Aquila, Andrew, additional, Hunter, Mark S., additional, Liang, Mengning, additional, Yoon, Chun Hong, additional, Zhao, Jingjing, additional, Zatsepin, Nadia A., additional, Abbey, Brian, additional, Sierecki, Emma, additional, Gambin, Yann, additional, Stacey, Katryn J., additional, Darmanin, Connie, additional, Kobe, Bostjan, additional, Xu, Hongyi, additional, and Ve, Thomas, additional

Published
2021
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44. MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography

Author

Clabbers, Max T. B., primary, Holmes, Susannah, additional, Muusse, Timothy W., additional, Vajjhala, Parimala, additional, Thygesen, Sara J., additional, Malde, Alpeshkumar K., additional, Hunter, Dominic J. B., additional, Croll, Tristan I., additional, Flueckiger, Leonie, additional, Nanson, Jeffrey D., additional, Rahaman, M. Habibur, additional, Aquila, Andrew, additional, Hunter, Mark S., additional, Liang, Mengning, additional, Yoon, Chun Hong, additional, Zhao, Jingjing, additional, Zatsepin, Nadia A., additional, Abbey, Brian, additional, Sierecki, Emma, additional, Gambin, Yann, additional, Stacey, Katryn J., additional, Darmanin, Connie, additional, Kobe, Bostjan, additional, Xu, Hongyi, additional, and Ve, Thomas, additional

Published
2021
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