157 results on '"Abd-Elrahman, Khaled S."'
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2. Targeting mGluR group III for the treatment of neurodegenerative diseases
3. Editorial: Emerging insights in glutamate receptor signaling in psychiatric, neurodevelopmental, and neurodegenerative diseases
4. Sexual dimorphism of G protein-coupled receptor signaling in the brain
5. Amelioration of perivascular adipose inflammation reverses vascular dysfunction in a model of nonobese prediabetic metabolic challenge: potential role of antidiabetic drugs
6. mGluR5 Allosteric Modulation Promotes Neurorecovery in a 6-OHDA-Toxicant Model of Parkinson’s Disease
7. A M1 muscarinic acetylcholine receptor-specific positive allosteric modulator VU0486846 reduces neurogliosis in female Alzheimer’s mice
8. VGLUT3 Deletion Rescues Motor Deficits and Neuronal Loss in the zQ175 Mouse Model of Huntington's Disease
9. mGluR5 regulates REST/NRSF signaling through N-cadherin/β-catenin complex in Huntington’s disease
10. The Role of Neuroglial Metabotropic Glutamate Receptors in Alzheimer’s Disease
11. Adipose tissue mitochondrial dysfunction and cardiometabolic diseases: On the search for novel molecular targets
12. Adipose tissue mitochondrial dysfunction and cardiometabolic diseases:On the search for novel molecular targets
13. Modulation of mTOR and CREB pathways following mGluR5 blockade contribute to improved Huntington’s pathology in zQ175 mice
14. Targeting mGluR2/3 for treatment of neurodegenerative and neuropsychiatric diseases
15. Editorial: Methods and application in cardiovascular and smooth muscle pharmacology: 2021
16. Sexual dimorphism of G prote-incoupled receptor signaling in the brain.
17. GRK2 knockdown in mice exacerbates kidney injury and alters renal mechanisms of blood pressure regulation
18. Autophagy is increased following either pharmacological or genetic silencing of mGluR5 signaling in Alzheimer’s disease mouse models
19. Early metabolic impairment as a contributor to neurodegenerative disease: Mechanisms and potential pharmacological intervention
20. VGLUT3 Ablation Differentially Modulates Glutamate Receptor Densities in Mouse Brain
21. Abnormal myosin phosphatase targeting subunit 1 phosphorylation and actin polymerization contribute to impaired myogenic regulation of cerebral arterial diameter in the type 2 diabetic Goto-Kakizaki rat
22. Abnormal Rho-associated kinase activity contributes to the dysfunctional myogenic response of cerebral arteries in type 2 diabetes
23. A positive allosteric modulator for the muscarinic receptor (M1 mAChR) improves pathology and cognitive deficits in female APPswe/PSEN1ΔE9 mice
24. Metabotropic Glutamate Receptor 5 Antagonism Reduces Pathology and Differentially Improves Symptoms in Male and Female Heterozygous zQ175 Huntington’s Mice
25. Noncanonical Metabotropic Glutamate Receptor 5 Signaling in Alzheimer's Disease
26. Metabotropic Glutamate Receptor 2/3 Activation Improves Motor Performance and Reduces Pathology in Heterozygous zQ175 Huntington Disease Mice
27. PKC-mediated cerebral vasoconstriction: Role of myosin light chain phosphorylation versus actin cytoskeleton reorganization
28. The pleiotropic effects of antithrombotic drugs in the metabolic–cardiovascular–neurodegenerative disease continuum: impact beyond reduced clotting
29. Optineurin deletion disrupts metabotropic glutamate receptor 5-mediated regulation of ERK1/2, GSK3β/ZBTB16, mTOR/ULK1 signaling in autophagy
30. Aβ oligomers induce pathophysiological mGluR5 signaling in Alzheimer’s disease model mice in a sex-selective manner
31. Sex-specific pathophysiological mGluR5-dependent Aβ oligomer signaling in Alzheimer mice
32. Targeting Vesicular Glutamate Transporter Machinery: Implications on Metabotropic Glutamate Receptor 5 Signaling and Behavior
33. Pioglitazone abrogates cyclosporine-evoked hypertension via rectifying abnormalities in vascular endothelial function
34. Targeting VGLUT Machinery: Implications on mGluR5 Signaling and Behavior
35. mGluR5 Contribution to Neuropathology in Alzheimer Mice Is Disease Stage-Dependent
36. Stromatoxin-sensitive, heteromultimeric Kv2.1/Kv9.3 channels contribute to myogenic control of cerebral arterial diameter
37. mGluR5 Allosteric Modulation Promotes Neurorecovery in a 6-OHDA-Toxicant Model of Parkinson’s Disease
38. Structural determinants governing β-arrestin2 interaction with PDZ proteins and recruitment to CRFR1
39. Aβ oligomers induce sex-selective differences in mGluR5 pharmacology and pathophysiological signaling in Alzheimer mice
40. Podocyte NADPH Oxidase 5 Promotes Renal Inflammation Regulated by the Toll-Like Receptor Pathway
41. mGluR5 regulates ZBTB16 pathway of autophagy in Alzheimer's disease in a sex‐specific manner
42. Amyloid Β Oligomers Induce Sex-Specific Pathophysiological mGluR5 Signaling in Alzheimer Mice
43. Metabotropic glutamate receptor 5 (mGluR5) blockade ameliorates Huntington's disease pathology via activating convergent mechanisms of autophagy
44. mGluR5 antagonism increases autophagy and prevents disease progression in the zQ175 mouse model of Huntington’s disease
45. ROK and Arteriolar Myogenic Tone Generation: Molecular Evidence in Health and Disease
46. Vascular Smooth Muscle-Specific EP4 Receptor Deletion in Mice Exacerbates Angiotensin II-Induced Renal Injury
47. Abnormal myosin phosphatase targeting subunit 1 phosphorylation and actin polymerization contribute to impaired myogenic regulation of cerebral arterial diameter in the type 2 diabetic Goto-Kakizaki rat
48. PPARγ Dependence of Cyclosporine–Isoprenaline Renovascular Interaction: Roles of Nitric Oxide Synthase and Heme Oxygenase
49. Role of PPARγ/Nitric Oxide Synthase Signaling in the Cyclosporine-induced Attenuation of Endothelium-dependent Renovascular Vasodilation
50. Pioglitazone Ameliorates Cyclosporine‐Induced Attenuation Of Carbachol Renovascular Vasodilations: Role Of PPARγ/Nitric Oxide Synthase Signaling
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