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157 results on '"Abdellaoui, Mohamed"'

1. Bowel obstruction complicating an encapsulating peritoneal sclerosis: A case report

Author

Messaoud Ola, MD, El Mansoury Fatima Zahra, MD, Cherraqi Amine, MD, Abdellaoui Mohamed, MD, PhD, Fenni Jamal, MD, PhD, and Saouab Rachida, MD, PhD

Subjects
Bowel obstruction, Cocoon abdomen, Encapsulating peritoneal sclerosis, Medical physics. Medical radiology. Nuclear medicine, R895-920
Abstract

Encapsulating peritoneal sclerosis (EPS) is a rare pathological entity that can be classified into an idiopathic or secondary affection. Bowel obstruction is a frequent complication that has a characteristic radiological finding, with a cocoon appearance. We present the case of a 40-year-old man who suffered an absolute constipation. He underwent a CT scan that was suggestive of encapsulating peritoneal sclerosis or abdominal cocoon responsible for small bowel obstruction.

Published
2024
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3. Application of the Water Quality Index to Assess Groundwater Quality in the Bou Dhar Mining District in Beni Tajjit (High Atlas, Morocco)

Author

Abdellaoui Mohamed, Abdellaoui Omar, Abdaoui Abdellali, and Ait Ali Boughrous

Subjects
tme, morocco, wqi, groundwater quality, bou dhar mine, high oriental atlas, mining discharges, Ecology, QH540-549.5
Abstract

Water scarcity remains the main problem in Morocco, making water resource conservation paramount. The objective of this study is to shed light on how mining impacts the region of Beni Tajjit's groundwater resources, which are used for irrigation and watering, which includes the Bou Dhar mining district, known for its vast lead and zinc sulfide deposits. The oxidation of sulfide-rich mine tailings generates acid water loaded with sulfates, creating acid mine drainage (AMD), which hurts aquatic ecosystems and the environment through trace metals elements (TME). Hence the need to assess the possible contamination of aquifers by metallic pollutants. This work can help water managers make appropriate decisions for controlling the quality of the groundwater in the Beni Tajjit area. During this study, we adopted a method: the Water Quality Index (WQI), designed to indicate the overall level of water quality by aggregating various weighted measurements. Five samples representing water sources around the mine tailings were taken and analyzed. Their values of dissolved oxygen, electrical conductivity, and pH were measured on-site. The results allow us to classify the water into good and bad categories. They showed that the TME values were practically lower than the maximum permitted level according to WHO norms and Moroccan irrigation standards. The main reason for this may be due to the carbonate geological context of the site, which buffers acidity and thus forms a chemical barrier against the transfer of TME to the aquifer. The high chlorine levels appear due to geochemical background or anthropogenies contaminations. The sulfate values recorded are related to the leaching of sulfide minerals from mine tailings.

Published
2023
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10. Direct wire pacing for transcatheter mitral valve replacement

Author

Servoz, Clément, primary, Wintzer-Wehekind, Jérôme, additional, Paradis, Jean-Michel, additional, Champagnac, Didier, additional, Charbonnier, Gaetan, additional, Farjat-Pasos, Julio, additional, Abdellaoui, Mohamed, additional, Dumonteil, Nicolas, additional, and Faurie, Benjamin, additional

Published
2023
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12. TCT-185 Safety and Performance Registry for an All-Comers Subject Population With the Limus-Eluting Orsiro Mission Stent System Within Daily Clinical Practice: 12-Month Results of the BIOFLOW-VIII Registry

Author

Barragan, Paul, primary, Maillard, Luc, additional, Morel, Olivier, additional, Delarche, Nicolas, additional, de Poli, Fabien, additional, Morelle, Jean-François, additional, Lesault, Pierre-François, additional, Tirouvanziam, Ashok, additional, Biron, Yves, additional, St Etienne, Christophe, additional, Range, Gregoire, additional, Lhoest, Nicolas, additional, Jeanneteau, Julien, additional, Quaino, Gonzalo, additional, Bellemain, Anne, additional, Digne, Franck, additional, Chapon, Philippe, additional, Fradi, Sahbi, additional, Boueri, Ziad, additional, Rosencher, Julien, additional, Labeque, Jean-Noel, additional, Abdellaoui, Mohamed, additional, Piot, Christophe, additional, Filippi, Emmanuelle, additional, Petroni, Thibaut, additional, Shayne, John, additional, Austruy, Julien, additional, Robin, Christophe, additional, Brimont, Olivier, additional, Boukantar, Madjid, additional, Lafont, Alexandre, additional, Bourkaib, Ryad, additional, Decoulx, Eric, additional, Valy, Yann, additional, Motreff, Pascal, additional, Staat, Patrick, additional, Valla, Matthieu, additional, Durand, Philippe, additional, Colin, Patrice, additional, Pouillot, Christophe, additional, Goube, Pascal, additional, Vrolix, Mathias, additional, and Lattuca, Benoit, additional

Published
2023
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15. Plasma amyloid levels within the Alzheimer's process and correlations with central biomarkers

Author

Hanon, Olivier, Blanc, Frédéric, Boudali, Yasmina, Gabelle, Audrey, Seux, Marie–Laure, Lenoir, Hermine, Bayle, Catherine, Bombois, Stéphanie, Delbeuck, Xavier, Moulin, Florence, Duron, Emmanuelle, Latour, Florence, Plichart, Matthieu, Pichierri, Sophie, Orvoën, Galdric, Galbrun, Evelyne, Castelnovo, Giovanni, Volpe–Gillot, Lisette, Labourée, Florien, Cassagnaud, Pascaline, Paquet, Claire, Lala, Françoise, Dumurgier, Julien, Rigaud, Anne–Sophie, Perret–Guillaume, Christine, Alonso, Eliana, du Boisgueheneuc, Foucaud, Hugonot–Diener, Laurence, Rollin–Sillaire, Adeline, Martinaud, Olivier, Boully, Clémence, Spivac, Yann, Devendeville, Agnès, Belmin, Joël, Robert, Philippe–Henri, Dantoine, Thierry, Caillard, Laure, Wallon, David, Hannequin, Didier, Sastre, Nathalie, Haffen, Sophie, Kearney–Schwartz, Anna, Novella, Jean–Luc, Deramecourt, Vincent, Chauvire, Valérie, Abitbol, Gabiel, Schwald, Nathalie, Hommet, Caroline, Sellal, François, Cariot, Marie–Ange, Abdellaoui, Mohamed, Benisty, Sarah, Gherabli, Salim, Anthony, Pierre, Bloch, Frédéric, Charasz, Nathalie, Chauvelier, Sophie, Gaubert, Jean–Yves, Sacco, Guillaume, Guerin, Olivier, Boddaert, Jacques, Paccalin, Marc, Mackowiak, Marie–Anne, Rabus, Marie–Thérèse, Gissot, Valérie, Benetos, Athanase, Picard, Candice, Guillemaud, Céline, Gervais, Claire, Hugon, Jaques, Michel, Jean–Marc, David, Jean–Philippe, Paulin, Marion, Ousset, Pierre–Jean, Vandel, Pierre, Pariel, Sylvie, Camus, Vincent, Chawakilian, Anne, Joffredo, Léna, Troussiere, Anne–Cécile, Adam, Cécile, Dupuy, Diane, Paillaud, Elèna, Briault, Hélène, Saulnier, Isabelle, Mondon, Karl, Picat, Marie–Agnès, Laurent, Marie, Godefroy, Olivier, Daheb, Rezki, Libercier, Stéphanie, Krabchi, Djamila, Chupin, Marie, Vidal, Jean–Sébastien, Chaussade, Edouard, Lehmann, Sylvain, Schraen-Maschke, Suzanna, Vidal, Jean-Sébastien, Allinquant, Bernadette, Tréluyer, Jean-Marc, Gelé, Patrick, Delmaire, Christine, Blanc, Fredéric, Mangin, Jean-François, Buée, Luc, Touchon, Jacques, Hugon, Jacques, Vellas, Bruno, Berrut, Gilles, Volpe-Gillot, Lisette, Robert, Philippe-Henri, Novella, Jean-Luc, and Rigaud, Anne-Sophie

Published
2018
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17. Groundwater Quality in the Vicinity of an Abandoned Mining Site -- The M'fis Mine, Southeast of Morocco.

Author

Abdellaoui, Mohamed, Abdaoui, Abdellali, Boukhoubza, Fadila, and Boughrous, Ali Ait

Subjects
GROUNDWATER quality, ABANDONED mined lands reclamation, CHEMICAL elements, POLLUTANTS
Abstract

The diagnosis of the current state of the environment (groundwater quality and tailings composition) was carried out in the vicinity of the M'fis mine (Southeast of Morocco) in order to evaluate the impact of mine tailings on groundwater. Water samples from the well in the center of the mine site and from other nearby wells were collected and analyzed. In addition, the characterization of the tailings shows the presence of sulfides and other chemical elements, constituting the main source of pollution. In turn, the results of geochemical analyses show that groundwater is characterized by low levels of metals, despite the presence of these pollutants in the tailings and in the waste rock piles. The concentrations of metallic trace elements in well groundwater, slightly exceeding the standards of potability (the WHO standard), remain acceptable for irrigation and for livestock. These results can be explained by the carbonate geological formation, constituting the transfer medium of the pollutants towards the aquifer and also by the weak circulation of the metal ions under the desert climate which prevent dissolution and infiltration. [ABSTRACT FROM AUTHOR]

Published
2023
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19. DELVING INTO THE NEXUS OF COLLABORATION AND SUPPLY CHAIN PERFORMANCE. EMPIRICAL EVIDENCE FROM AUTOMOTIVE INDUSTRY.

Author

Boubker, Omar, Naoui, Khaled, El Abdellaoui, Mohamed, and Lafdili, Ahmed

Subjects
SUPPLY chains, SUPPLY chain management, BUSINESS success, AUTOMOBILE industry, CONVENIENCE sampling (Statistics)
Abstract

Background: Supply chain management (SCM) practices play a significant role in modern business success through coordinating the continuous flow of goods, services and information within complex networks. At this level, the collaboration between supply chain (SC) members constitutes an important determinant of supply chain performance. Therefore, this study aims to explore the effect of supply chain collaboration dimensions, i.e., such as decision synchronization, collaborative communication, incentive alignment, goal congruence, information sharing joint knowledge creation, and resource sharing, on the level of supply chain performance. Methods: The dataset was gathered using a convenience sampling procedure from middle and senior automotive SC executives. Partial least squares structural equation modeling (PLS-SEM) using SmartPLS software was carried out in order to analyze the data. Results: The results show that collaborative communication, information sharing, incentive alignment, joint knowledge creation, and goal congruence contribute considerably to enhancing the automotive SC performance. Conclusions: These findings have valuable implications for practitioners in order to adopt the appropriate practices to improve automotive SC performance. These insights can help to guide practitioners in implementing the appropriate collaborative practices to meet the specific challenges of the automotive supply chain. By considering these guidelines, practitioners will be able to streamline processes, optimize resource allocation and ultimately deliver more efficient outcomes, leading to improved overall automotive supply chain performance. [ABSTRACT FROM AUTHOR]

Published
2023
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21. Ticagrelor Monotherapy or Dual Antiplatelet Therapy After Drug‐Eluting Stent Implantation: Per‐Protocol Analysis of the GLOBAL LEADERS Trial

Author

Gragnano, Felice, primary, Zwahlen, Marcel, additional, Vranckx, Pascal, additional, Heg, Dik, additional, Schmidlin, Kurt, additional, Hamm, Christian, additional, Steg, Philippe Gabriel, additional, Gargiulo, Giuseppe, additional, McFadden, Eugene P., additional, Onuma, Yoshinobu, additional, Chichareon, Ply, additional, Benit, Edouard, additional, Möllmann, Helge, additional, Janssens, Luc, additional, Leonardi, Sergio, additional, Zurakowski, Aleksander, additional, Arrivi, Alessio, additional, Van Geuns, Robert Jan, additional, Huber, Kurt, additional, Slagboom, Ton, additional, Calabrò, Paolo, additional, Serruys, Patrick W., additional, Jüni, Peter, additional, Valgimigli, Marco, additional, Windecker, Stephan, additional, Abdellaoui, Mohamed, additional, Adlam, David, additional, Akin, Ibrahim, additional, Gonzalez‐Trevilla, Agustin Albarran, additional, Almeida, Manuel, additional, Neto, Pedro Alves Lemos, additional, Aminian, Adel, additional, Anderson, Richard, additional, Andreae, Rick, additional, Angioi, Michael, additional, Asano, Taku, additional, Barbato, Emanuele, additional, Barlis, Peter, additional, Barraud, Pascal, additional, Bertrand, Olivier, additional, Beygui, Farzin, additional, Bolognese, Leonardo, additional, Botelho, Roberto, additional, Bouwman, Coby, additional, Bressers, Marco, additional, Brunel, Philippe, additional, Buszman, Pawel, additional, Buysschaert, Ian, additional, da Silva, Pedro Canas, additional, Carrie, Didier, additional, Cequier, Angel, additional, Chang, Chun Chin, additional, Chowdhary, Saqib, additional, Collet, Carlos, additional, Colombo, Antonio, additional, Cotton, James, additional, Ferreira, Rui Cruz, additional, Curello, Salvatore, additional, Curzen, Nick, additional, de Bot, Judith, additional, de Vreede, Tone, additional, Karth, Georg Delle, additional, Dijksma, Lynn, additional, Dominici, Marcello, additional, Édes, István, additional, Eeckhout, Eric, additional, Eitel, Ingo, additional, Faluközy, József, additional, Fath‐Ordoubadi, Farzin, additional, Ferrario, Maurizio, additional, Fontos, Geza, additional, Diaz, Jose Francisco, additional, Quintella, Edgard Freitas, additional, Frey, Bernhard, additional, Friedrich, Guy, additional, Galasko, Gavin, additional, Galuszka, Grzegorz, additional, Ribeiro, Vasco Gama, additional, Garg, Scot, additional, Geisler, Tobias, additional, Gelev, Valeri, additional, Ghandilyan, Art, additional, Goicolea, Javier, additional, Gori, Tommaso, additional, Gragnano, Felice, additional, Guimarães, Ana, additional, Haude, Michael, additional, Heijke, Pieter, additional, Antolin, Rosa Ana Hernández, additional, Hildick‐Smith, David, additional, Hillen, Dorien, additional, Hoekman, Ina, additional, Hofma, Sjoerd, additional, Holmvang, Lene, additional, Hoole, Stephen, additional, Horváth, Iván, additional, Hugense, Annemarie, additional, Ibrahim, Karim, additional, Iñiguez, Andres, additional, Isaaz, Karl, additional, Jambrik, Zoltán, additional, Jasionowicz, Pawel, additional, Jonk, Judith, additional, Jung, Werner, additional, Katagiri, Yuki, additional, Kogame, Norihiro, additional, Koh, Tian Hai, additional, Koning, René, additional, Konteva, Mariana, additional, Kőszegi, Zsolt, additional, Krackhardt, Florian, additional, Kreuger, Yvonne, additional, Kukreja, Neville, additional, Ladan, Boudijn, additional, Lantelme, Pierre, additional, Leandro, Sergio, additional, Leibundgut, Gregor, additional, Liebetrau, Christoph, additional, Lindeboom, Wietze, additional, Miguel, Carlos Macaya, additional, Mach, François, additional, Magro, Michael, additional, Maillard, Luc, additional, Manavifar, Negar, additional, Mauri, Laura, additional, McFadden, Eugene, additional, Merkely, Bela, additional, Miyazaki, Yosuke, additional, Młodziankowski, Adam, additional, Moccetti, Tiziano, additional, Modolo, Rodrigo, additional, Möllman, Helge, additional, Morelle, Jean‐François, additional, Moschovitis, Aris, additional, Ottesen, Michael Munndt, additional, Muurling, Martin, additional, Naber, Christoph Kurt, additional, Neumann, Franz‐Josef, additional, Oldroyd, Keith, additional, Ong, Paul, additional, Palsrok, Sanne, additional, Petrov, Ivo, additional, Plante, Sylvain, additional, Prokopczuk, Janusz, additional, Rademaker‐Havinga, Tessa, additional, Raffel, Christopher, additional, Rensing, Benno, additional, Roffi, Marco, additional, Royaards, Kees‐Jan, additional, Sabate, Manel, additional, Schächinger, Volker, additional, Seidler, Tim, additional, Peñaranda, Antonio Serra, additional, Serruys, Patrick, additional, Sikarulidze, Lali, additional, Soliman, Osama I, additional, Sousa, Amanda, additional, Spitzer, Ernest, additional, Stables, Rod, additional, Steg, Gabriel, additional, Steinwender, Clemens, additional, Subkovas, Eduardas, additional, Suryapranata, Harry, additional, Takahashi, Kuniaki, additional, Talwar, Suneel, additional, Teiger, Emmanuel, additional, Weele, Addy Ter, additional, Teurlings, Eva, additional, Thury, Attila, additional, Tijssen, Jan, additional, Tonev, Gincho, additional, Trendafilova‐Lazarova, Diana, additional, Tumscitz, Carlo, additional, Umans, Victor, additional, Ungi, Imre, additional, Valkov, Veselin, additional, van der Harst, Pim, additional, van Geuns, Robert Jan, additional, van Meijeren, Cokky, additional, Vassilev, Dobrin, additional, Velchev, Vasil, additional, Velthuizen, Esther, additional, Verheugt, Freek, additional, Vlcek, Natalia, additional, Dahl, Jürgen Vom, additional, Vrolix, Mathias, additional, Walsh, Simon, additional, Werner, Nikos, additional, Witsenburg, Maarten, additional, Zaman, Azfar, additional, Żmudka, Krzysztof, additional, Zrenner, Bernhard, additional, and Zweiker, Robert, additional

Published
2022
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22. Safety of conservative management for non-stenotic culprit lesions in STEMI patients treated with a two-step reperfusion strategy: a SUPER-MIMI sub-study

Author

Bonnet, Marc, primary, Marliere, Stephanie, additional, Mathieu, Victor, additional, Tronchi, Allan, additional, Delarche, Nicolas, additional, Abdellaoui, Mohamed, additional, Dubreuil, Olivier, additional, Boueri, Ziad, additional, Chettibi, Mohamed, additional, Souteyrand, Geraud, additional, Durier, Chloé, additional, Bouisset, Frederic, additional, and Belle, Loic, additional

Published
2022
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24. EXPLORING THE INFLUENCE OF IS ON COLLABORATION, AGILITY, AND PERFORMANCE. THE CASE OF THE AUTOMOTIVE SUPPLY CHAIN.

Author

Naoui, Khaled, Boubker, Omar, and El Abdellaoui, Mohamed

Subjects
MANAGEMENT information systems, INFORMATION resources management, SUPPLY chains, INFORMATION sharing, SUPPLY chain management
Abstract

Background: Supply chain information systems (SCIS) have turned into a key success factor for the proper management of the automotive supply chain. Therefore, the scope of this paper is to explore the impact of SC information system infrastructure (SCISI) and SC information sharing (ISSC) on interorganizational trust (IOT), SC collaboration (SCC), SC agility (SCA), and SC performance (SCP) in the Moroccan automotive industry context. Methods: The dataset was drawn from a selected sample of Moroccan automotive industry firms through an online survey. Furthermore, the partial least squares (PLS-SEM) procedure was applied to test the conceptual model. Results: The findings support the positive influence of SCIS infrastructure on IOT and SC agility. Similarly, information sharing in SC positively affects the collaboration between IOT and automotive SC. The results also provide evidence that IOT plays a significant role in improving SC agility. Lastly, agility and SC collaboration were identified as key drivers of SC of performance. Conclusions: The findings extend the existing literature on SC management and management information systems by providing empirical verification of how information sharing and IS infrastructure can influence collaboration, agility, and SC performance. These findings are useful in guiding SC managers through the process of improving SC performance. [ABSTRACT FROM AUTHOR]

Published
2023
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26. Polymer-free Drug-Coated Coronary Stents in Patients at High Bleeding Risk

Author

Urban, Philip, Meredith, Ian T., Abizaid, Alexandre, Pocock, Stuart J., Carrié, Didier, Naber, Christoph, Lipiecki, Janusz, Richardt, Gert, Iñiguez, Andres, Brunel, Philippe, Valdes-Chavarri, Mariano, Garot, Philippe, Talwar, Suneel, Berland, Jacques, Abdellaoui, Mohamed, Eberli, Franz, Oldroyd, Keith, Zambahari, Robaayah, Gregson, John, Greene, Samantha, Stoll, Hans-Peter, and Morice, Marie-Claude

Published
2015
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28. Benefit and Risks of Aspirin in Addition to Ticagrelor in Acute Coronary Syndromes: A Post Hoc Analysis of the Randomized GLOBAL LEADERS Trial

Author

Tomaniak, Mariusz, Chichareon, Ply, Onuma, Yoshinobu, Deliargyris, Efthymios N., Takahashi, Kuniaki, Kogame, Norihiro, Modolo, Rodrigo, Chang, Chun Ching, Rademaker-Havinga, Tessa, Storey, Robert F., Dangas, George D., Bhatt, Deepak L., Angiolillo, Dominick J., Hamm, Christian, Valgimigli, Marco, Windecker, Stephan, Steg, Philippe Gabriel, Vranckx, Pascal, Serruys, Patrick W., Bertrand, Olivier F., Plante, Sylvain, Van Geuns, Robert-Jan, Hofma, Sjoerd H., Royaards, Kees-Jan, Slagboom, Ton, Suryapranata, Harry, Umans, Victor A. W. M., Rensing, Benno, van der Harst, Pim, Magro, Michael, Barbato, Emanuel, Aminian, Adel, Benit, Edouard, Janssens, Luc, Vrolix, Mathias, Buysschaert, Ian, Carrie, Didier, Barraud, Pascal, Teiger, Emmanuel, Koning, Ren, Farzin, Beygui, Morelle, Jean-francois, Isaaz, Karl, Maillard, Luc, Abdellaoui, Mohamed, Brunel, Philippe, Angioi, Michael, Lantelme, Pierre, Sabate, Manel, Albarran Gonzalez-Trevilla, Agustin, Cardiology, Graduate School, ACS - Atherosclerosis & ischemic syndromes, ACS - Microcirculation, ACS - Heart failure & arrhythmias, and Cardiovascular Centre (CVC)

Subjects
Male, Ticagrelor, Internationality, Time Factors, medicine.medical_treatment, 030204 cardiovascular system & hematology, Severity of Illness Index, Tertiary Care Centers, Coronary artery disease, 0302 clinical medicine, Cause of Death, 030212 general & internal medicine, 610 Medicine & health, Original Investigation, Aspirin, DUAL ANTIPLATELET THERAPY, Continuity of Patient Care, Clopidogrel, Treatment Outcome, CLOPIDOGREL, Platelet aggregation inhibitor, Drug Therapy, Combination, Female, Cardiology and Cardiovascular Medicine, INTERVENTION, medicine.drug, Acute coronary syndrome, medicine.medical_specialty, Hemorrhage, Risk Assessment, Drug Administration Schedule, 03 medical and health sciences, Percutaneous Coronary Intervention, Internal medicine, medicine, Humans, Acute Coronary Syndrome, Dose-Response Relationship, Drug, RECEPTOR, business.industry, Percutaneous coronary intervention, IN-VITRO, medicine.disease, Survival Analysis, PLATO, Conventional PCI, business, Platelet Aggregation Inhibitors, Follow-Up Studies
Abstract

Key PointsQuestionWhat are the benefits and risks of continuing aspirin in addition to P2Y12 receptor inhibition with ticagrelor among patients with acute coronary syndrome between 1 month and 12 months after percutaneous coronary intervention? FindingsIn this nonprespecified, post hoc analysis of the GLOBAL LEADERS randomized clinical trial, beyond 1 month after percutaneous coronary intervention in acute coronary syndrome, aspirin was associated with increased bleeding risk and appeared not to add to the benefit of ticagrelor on ischemic events. MeaningThe findings of this hypothesis-generating analysis pave the way for further trials evaluating aspirin-free antiplatelet strategies after percutaneous coronary intervention.ImportanceThe role of aspirin as part of antiplatelet regimens in acute coronary syndromes (ACS) needs to be clarified in the context of newer potent P2Y12 antagonists. ObjectiveTo evaluate the benefit and risks of aspirin in addition to ticagrelor among patients with ACS beyond 1 month after percutaneous coronary intervention (PCI). Design, Setting, and ParticipantsThis is a nonprespecified, post hoc analysis of GLOBAL LEADERS, a randomized, open-label superiority trial comparing 2 antiplatelet treatment strategies after PCI. The trial included 130 secondary/tertiary care hospitals in different countries, with 15991 unselected patients with stable coronary artery disease or ACS undergoing PCI. Patients had outpatient visits at 1, 3, 6, 12, 18, and 24 months after index procedure. InterventionsThe experimental group received aspirin plus ticagrelor for 1 month followed by 23-month ticagrelor monotherapy; the reference group received aspirin plus either clopidogrel (stable coronary artery disease) or ticagrelor (ACS) for 12 months, followed by 12-month aspirin monotherapy. In this analysis, we examined the clinical outcomes occurring between 31 days and 365 days after randomization, specifically in patients with ACS who, within this time frame, were assigned to receive either ticagrelor alone or ticagrelor and aspirin. Main Outcomes and MeasuresThe primary outcome was the composite of all-cause death or new Q-wave myocardial infarction. ResultsOf 15968 participants, there were 7487 patients with ACS enrolled; 3750 patients were assigned to the experimental group and 3737 patients to the reference group. Between 31 and 365 days after randomization, the primary outcome occurred in 55 patients (1.5%) in the experimental group and in 75 patients (2.0%) in the reference group (hazard ratio [HR], 0.73; 95% CI, 0.51-1.03; P=.07); investigator-reported Bleeding Academic Research Consortium-defined bleeding type 3 or 5 occurred in 28 patients (0.8%) in the experimental group and in 54 patients (1.5%) in the reference arm (HR, 0.52; 95% CI, 0.33-0.81; P=.004). Conclusions and RelevanceBetween 1 month and 12 months after PCI in ACS, aspirin was associated with increased bleeding risk and appeared not to add to the benefit of ticagrelor on ischemic events. These findings should be interpreted as exploratory and hypothesis generating; however, they pave the way for further trials evaluating aspirin-free antiplatelet strategies after PCI. Trial RegistrationClinicalTrials.gov identifier: NCT01813435.This secondary analysis of the GLOBAL LEADERS randomized clinical trial evaluates the benefit and risks of aspirin in addition to ticagrelor among patients with acute coronary syndrome beyond 1 month after percutaneous coronary intervention.

Published
2019

39. Use and outcomes of the PK Papyrus covered stent in France: SOS PK Papyrus Registry

Author

Hernández‐Enríquez, Marco, primary, Belle, Loic, additional, Madiot, Hende, additional, Pansieri, Michel, additional, Souteyrand, Geraud, additional, de Poli, Fabiel, additional, Piot, Christophe, additional, Boueri, Ziad, additional, Gerbaud, Edouard, additional, Boiffard, Emmanuel, additional, Benamer, Hakim, additional, Lattuca, Benoit, additional, Commeau, Philippe, additional, Gervasoni, Richard, additional, Rangé, Gregoire, additional, Lhoest, Nicolas, additional, Marliere, Stéphanie, additional, Abdellaoui, Mohamed, additional, Delarche, Nicolas, additional, Zemour, Gilles, additional, Armengaud, Jean, additional, Carre, Max, additional, Levesque, Sebastien, additional, and Boudou, Nicolas, additional

Published
2020
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41. Polymer-free drug-coated vs. bare-metal coronary stents in patients undergoing non-cardiac surgery: a subgroup analysis of the LEADERS FREE trial

Author

Richardt, Gert, primary, Abdelghani, Mohammad, additional, Allali, Abdelhakim, additional, Toelg, Ralph, additional, Abdellaoui, Mohamed, additional, Krackhardt, Florian, additional, Wiseth, Rune, additional, Morice, Marie-Claude, additional, Copt, Samuel, additional, Stoll, Hans-Peter, additional, and Urban, Philip, additional

Published
2020
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47. At least seven days delayed stenting using minimalist immediate mechanical intervention (MIMI) in ST-segment elevation myocardial infarction: the SUPER-MIMI study

Author

Derimay, François, Souteyrand, Geraud, Motreff, Pascal, Rioufol, Gilles, Finet, Gérard, Mester, Petru, Bouvaist, Hélène, Delarche, Nicolas, Bouisset, Frédéric, Abdellaoui, Mohamed, Petiteau, Pierre-Yves, Dubreuil, Olivier, Boueri, Ziad, Chettibi, Mohamed, Madiot, Hend, Belle, Loic, CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand, Institut Pascal (IP), SIGMA Clermont (SIGMA Clermont)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Hôpital Cardiovasculaire Louis Pradel, Hospices Civils de Lyon (HCL), Department of Hemodynamics and Interventional Cardiology, Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Cardiologie, CHU Grenoble, Centre hospitalier de Pau, Service de cardiologie [Toulouse], Hôpital de Rangueil, CHU Toulouse [Toulouse]-CHU Toulouse [Toulouse], Cardioprotection, Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalo-Universitaire de Blida (CHU Blida), Centre hospitalier de la région d'Annecy, SIGMA Clermont (SIGMA Clermont)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), Service Cardiologie [CHU Toulouse], Pôle Cardiovasculaire et Métabolique [CHU Toulouse], and Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)

Subjects
Adult, Male, medicine.medical_specialty, Time Factors, medicine.medical_treatment, Myocardial Infarction, Platelet Glycoprotein GPIIb-IIIa Complex, 030204 cardiovascular system & hematology, Coronary Angiography, Ventricular Function, Left, 03 medical and health sciences, Percutaneous Coronary Intervention, 0302 clinical medicine, Fibrinolytic Agents, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Interquartile range, Coronary Circulation, Internal medicine, medicine, Clinical endpoint, Humans, ST segment, Prospective Studies, cardiovascular diseases, 030212 general & internal medicine, Myocardial infarction, ComputingMilieux_MISCELLANEOUS, Aged, business.industry, Percutaneous coronary intervention, Thrombolysis, Middle Aged, medicine.disease, 3. Good health, Stenosis, Cardiology, ST Elevation Myocardial Infarction, Female, Cardiology and Cardiovascular Medicine, business, TIMI
Abstract

Aims The aim of this study was to ascertain whether a minimalist immediate mechanical intervention (MIMI) aiming to restore an optimal Thrombolysis In Myocardial Infarction (TIMI) flow in the culprit artery, followed ≥7 days later by a second percutaneous coronary intervention with intentional stenting, is safe in patients with ST-segment elevation myocardial infarction and large thrombotic burden. Methods and results SUPER-MIMI was a prospective, observational trial conducted between January 2014 and April 2015 in 14 French centres. A total of 155 patients were enrolled. The pharmacological therapy was left to the operator's discretion. Eighty-one patients (52.3%) had glycoprotein IIb/IIIa inhibitors (GPI) initiated before the end of the first procedure. The median (interquartile range [IQR]) delay between the two procedures was eight (seven to 12) days. Infarct-related artery reocclusion between the two procedures (primary endpoint) occurred in two patients (1.3%), neither of whom received GPI treatment. TIMI flow was maintained or improved between the end of the first procedure and the beginning of the second procedure in all patients. Thrombotic burden and stenosis severity diminished significantly between the two procedures. Stents were ultimately implanted in 97 patients (62.6%). Conclusions Deferred stenting (≥7 days) in patients with a high thrombus burden was safe on a background of GPI therapy.

Published
2017

48. Use and outcomes of the PK Papyrus covered stent in France: SOS PK Papyrus Registry.

Author

Hernández‐Enríquez, Marco, Belle, Loic, Madiot, Hende, Pansieri, Michel, Souteyrand, Geraud, de Poli, Fabiel, Piot, Christophe, Boueri, Ziad, Gerbaud, Edouard, Boiffard, Emmanuel, Benamer, Hakim, Lattuca, Benoit, Commeau, Philippe, Gervasoni, Richard, Rangé, Gregoire, Lhoest, Nicolas, Marliere, Stéphanie, Abdellaoui, Mohamed, Delarche, Nicolas, and Zemour, Gilles

Published
2021
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