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Background: Seroma is the most common complication occurring after surgery for breast cancer, leading to patient discomfort, recurrent aspirations with the risk of inflammations, long hospital stay, delayed wound healing, skin flap damage, delay in treatment with adjuvant therapies, and high surgical costs. The purpose of our study is short term follow up" within two months after operation" to compare the effectiveness of using Tetracycline and reducing the dead space in reducing seroma after Modified Radical Mastectomy (MRM). Patients and methods: Interventional study was applied on 56 females having breast cancer to evaluate different techniques for reduction of seroma formation after modified radical mastectomy at department of general surgery, Zagazig University Hospitals, during the time from October 2018 to April 2020. Patients were divided into two groups each one enrolls 28 patients Group A: we used tetracycline, suction drain and tight bandage while in Group B: we used mechanical closure of dead space, suction drain and tight bandage. All patients were subjected to history taking, complete clinical examination, Laboratory tests and breast ultrasound. Results: In this study the percentage of seroma occurred in total cases was (26.8%) this is considered good results when compared to worldwide percentage (73%). In group A (Tetracycline) seroma occurred in 32% of 28 cases and 21.4% of 28 cases in group B. Conclusion: There was no significant difference between using Tetracycline and closing the dead space in decreasing seroma formation after MRM. [ABSTRACT FROM AUTHOR]

Background: Lichtenstein repair is the standard surgical method of inguinal hernia. The impact of the mesh repair on the testis and incidence of infertility after the mesh repair is still a subject of discussion. The aim of this study was to evaluate the testicular functions after tension free mesh repair of bilateral inguinal hernia. Subjects and methods: In the period between October 2018 and April 2019 in the General Surgery Department of Zagazig University and Al Ahrar teaching Hospitals, 18 male patients with bilateral inguinal hernia ranging between 20 and 40 years were subjected to Lichtenstein tension free mesh repair. All the patients have been evaluated pre & 6 months postoperatively to assess the testicular functions after the repair. Results: No significant differences have been noted between the pre & postoperative fertility parameters which include the testicular volume and perfusion measured by scrotal Doppler ultrasound, semen quality which determine spermatogenesis and hormonal assessment which evaluate the endocrinological status. Conclusions: Lichtenstein tension free mesh repair is an effective procedure for the repair of bilateral inguinal hernia when an experienced surgeon in laparoscopic repair isn't present. It is a safe method with less complication rates regarding recurrence, pain. Also, it can be used in the young adults using a synthetic mesh without any fear for the future fertility of those patients. [ABSTRACT FROM AUTHOR]

Background: Seroma is the most common problem occurring after breast cancer surgery, causing patient discomfort, repeated seroma aspirations with the risk of infection, prolonged hospital stay, delayed wound healing, skin flap necrosis, delay in receiving adjuvant therapies, and higher surgical expenditures. The purpose of our study is short term follow up" within two months after operation" to evaluate the effectiveness of using Tetracycline and closure of the dead space in reducing seroma after Modified Radical Mastectomy (MRM). Patients and methods: Interventional study was conducted on 56 females with breast cancer to evaluate different techniques for reduction of seroma formation after modified radical mastectomy at general surgery department of Zagazig University Hospitals, during the period from October 2018 to April 2020. Patients were divided into 2 groups each one enrolls 28 patients Group A: we used tetracycline, suction drain and tight bandage while in Group B: we used mechanical closure of dead space, suction drain and tight bandage, "without tetracycline" All patients were subjected to Demographic data taking, complete clinical examination, Laboratory investigations and breast ultrasound. Results: In this study the percentage of seroma occurred in total cases was (26.8%) this is considered good results when compared to worldwide percentage (73%). In group A (Tetracycline) seroma occurred in 32% of 28 cases and 21.4% of 28 cases in group B. Conclusion: There was no significant difference between using Tetracycline and mechanical closure of dead space in reducing seroma after MRM. [ABSTRACT FROM AUTHOR]

The article presents randomized control study on the role of tetracycline in prevention of post modified radical mastectomy seroma. Topics include modified radical mastectomy (MRM) is the principal treatment of breast cancer, provides sufficient tumor clearance, and decrease the local recurrence rate; and topical sclerotherapy with Tetracycline has long been used successfully in the treatment of malignant pleural effusions to cause obliteration of the pleural space.