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30 results on '"Abdelrahman, Amany"'

4. The association between ADAMTS14/rs4747096 gene polymorphism and some risk factors and knee osteoarthritis

Author

Elshaarawy, Ghada A., primary, Salama, Iman I, additional, Salama, Somaia I, additional, Abdelrahman, Amany H, additional, Hassan, Mirhane, additional, Eissa, Eman, additional, Ismail, Sherif, additional, Eldeeb, Sherif E., additional, Ahmed, Doaa E., additional, Elhariri, Hazem, additional, Elgohary, Rasmia, additional, Abdelmohsen, Aida M, additional, Fouad, Walaa A, additional, and Raslan, Hala M, additional

Published
2024
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6. Impact of erythropoietin and myoinositol versus metformin on insulin resistance in a rat model of polycystic ovary syndrome.

Author

Abdelrahman, Amany, Mahmoud, Aida Abdeen, Lamie Fanous, Youstina, Abd Elhaliem, Nesreen Gamal, and Elalaf, Hassan

Subjects
*METFORMIN, *POLYCYSTIC ovary syndrome, *INOSITOL, *INSULIN resistance, *INDUCED ovulation, *ERYTHROPOIETIN, *ANIMAL disease models
Abstract

This study aimed to evaluate the therapeutic role of erythropoietin (EPO) or myoinositol versus metformin (MET) in improving the reproductive functions and glucose tolerance in a rat model of polycystic ovary (PCOS). Oral letrozole (LTZ) was used for induction of PCOS in wester rats for 21 days, after that, MET, EPO and myoinositol were administered for the following 21 days. The LTZ-induced PCOS rats have lost their oestrous cyclicity and become fixed at the diestrus phase, developed insulin resistance, abnormal sex and gonadotrophin hormone serum levels, increased cystic follicles, decreased number of the growing follicles and very little or no corpora lutea on microscopic examination, which were reversed by the three drugs, MET, EPO and myoinositol. MET and myoinositol were mostly equally effective in improving the reproductive manifestations of the disease. However, EPO was most effective in decreasing the insulin level observed in this LTZ-induced model of PCOS. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Evaluation of prognostic variables in chronic lymphocytic leukemia and association with disease stage

Author

Attia, Hanaa, primary, Ibrahim, Mona, additional, Abd El‑Aziz, Shereen, additional, Abdelrahman, Amany, additional, Sobeih, Mohamed, additional, Hagag, Heba, additional, Yassa, Marianne, additional, Osman, Randa, additional, Rawi, Rasha, additional, Abd El‑Dayem, Omnia, additional, Elsharkawi, Nahla, additional, Abdelfattah, Raafat, additional, and Hassan, Naglaa, additional

Published
2021
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22. Additional file 1 of Forced exercise activates the NrF2 pathway in the striatum and ameliorates motor and behavioral manifestations of Parkinson's disease in rotenone-treated rats

Author

Monir, Dina M., Motamed E. Mahmoud, Omyma G. Ahmed, Rehan, Ibrahim F., and Abdelrahman, Amany

Subjects
fungi
Abstract

Additional file1: Figure S1. The effects of exercise on serum levels of CPK and LDH in control groups, * if the differences were significantly different from the control group.

Published
2020
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23. ITGA4 gene methylation status in chronic lymphocytic leukemia

Author

Attia, Hanaa RM, primary, Ibrahim, Mona Hamed, additional, El-Aziz, Shereen H Abd, additional, Hassan, Naglaa M, additional, Osman, Randa A, additional, Hagag, Heba A, additional, Yassa, Marianne E, additional, Abdelrahman, Amany H, additional, Salama, Iman I, additional, and Sobeih, Mohamed Emam, additional

Published
2020
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30. Evaluation of BRCA1 Large Genomic Rearrangements in Group of Egyptian Female Breast Cancer Patients Using MLPA.

Author

Eid OM, El Ghoroury EA, Eid MM, Mahrous RM, Abdelhamid MI, Aboafya ZI, Abdel Ghaffar EA, and Abdelrahman AH

Subjects
Breast Neoplasms pathology, Egypt, Female, Humans, BRCA1 Protein genetics, Breast Neoplasms genetics, Gene Rearrangement genetics, Multiplex Polymerase Chain Reaction methods
Abstract

Introduction: Breast cancer is one of the most widespread cancers affecting women all over the world. In Egypt, it is considered to be the first cause of malignancies among female. BRCA1 Large Genomic Rearrangements (LGRs) have been reported in hereditary breast families and occurs in considerable proportion of cases in various populations., Objective and Methods: We investigated the incidence of BRCA1 LGRs in group of Egyptian females with breast cancer using Multiplex Ligation-dependent Probe Amplification (MLPA) assay., Results: Thirty six female breast cancer patients were included in this study. There were no BRCA1 LGRs detected in the studied group of patients which does not coincide with other study that were done on a group of Egyptian female patients., Discussion and Conclusion: This variance may be due to the small number of the investigated patients in both studies, which is considered as a limitation. So, screening for LGRs of BRCA1 gene as well as other genes that may be involved in breast cancer such as BRCA2 and CHEK2 genes of a larger number of patients is recommended to get the actual prevalence of these gene in the Egyptian population to deliver a cost-effective primary approach for these patients.

Published
2017

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