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1,178 results on '"Abete, Pasquale"'

6. Clinical Magnet Application to Temporarily Inhibit Subcutaneous Implantable Cardioverter Defibrillators Therapy in Emergency Situations: One size fits all.

Author

Santomauro, Maurizio, primary, Petretta, Mario, additional, cacciatore, francesco, additional, riganti, carla, additional, santomauro, andrea, additional, Castellano, Gaetano, additional, Viggiano, Aniello, additional, iovino, gianluigi, additional, Rapacciuolo, Antonio, additional, Mafettone, Francesco, additional, and Abete, Pasquale, additional

Published
2024
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8. Common variants at 21q22.3 locus influence MX1 and TMPRSS2 gene expression and susceptibility to severe COVID-19

Author

Andolfo, Immacolata, Russo, Roberta, Lasorsa, Vito Alessandro, Cantalupo, Sueva, Rosato, Barbara Eleni, Bonfiglio, Ferdinando, Frisso, Giulia, Abete, Pasquale, Cassese, Gian Marco, Servillo, Giuseppe, Esposito, Gabriella, Gentile, Ivan, Piscopo, Carmelo, Villani, Romolo, Fiorentino, Giuseppe, Cerino, Pellegrino, Buonerba, Carlo, Pierri, Biancamaria, Zollo, Massimo, Iolascon, Achille, and Capasso, Mario

Published
2021
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9. RAAS inhibitors are not associated with mortality in COVID-19 patients: Findings from an observational multicenter study in Italy and a meta-analysis of 19 studies

Author

Di Castelnuovo, Augusto, Costanzo, Simona, Antinori, Andrea, Berselli, Nausicaa, Blandi, Lorenzo, Bonaccio, Marialaura, Cauda, Roberto, Gialluisi, Alessandro, Guaraldi, Giovanni, Menicanti, Lorenzo, Mennuni, Marco, Mussinelli, Roberta, My, Ilaria, Parruti, Giustino, Patti, Giuseppe, Perlini, Stefano, Santilli, Francesca, Signorelli, Carlo, Stefanini, Giulio G., Vergori, Alessandra, Abete, Pasquale, Ageno, Walter, Agostoni, Piergiuseppe, Aiello, Luca, Al Moghazi, Samir, Arboretti, Rosa, Aucella, Filippo, Barbieri, Greta, Barchitta, Martina, Bartoloni, Alessandro, Bonfanti, Paolo, Cacciatore, Francesco, Caiano, Lucia, Carrozzi, Laura, Cascio, Antonio, Castiglione, Giacomo, Cianfrone, Stefania, Ciccullo, Arturo, Cingolani, Antonella, Cipollone, Francesco, Colomba, Claudia, Colombo, Crizia, Cozzi, Ottavia, Crisetti, Annalisa, Crosta, Francesca, Danzi, Gian Battista, D'Ardes, Damiano, de Gaetano Donati, Katleen, Di Gennaro, Francesco, Di Tano, Giuseppe, D'Offizi, Gianpiero, Fusco, Francesco Maria, Gentile, Ivan, Graziani, Emauele, Guarnieri, Gabriella, Larizza, Giovanni, Leone, Armando, Lio, Veronica, Lucia, Mothanje Barbara, Maccagni, Gloria, Madaro, Ferruccio, Maitan, Stefano, Mancarella, Sandro, Manuele, Rosa, Mapelli, Massimo, Maragna, Riccardo, Marcucci, Rossella, Maresca, Giulio, Marongiu, Silvia, Marotta, Claudia, Marra, Lorenzo, Mastroianni, Franco, Mazzitelli, Maria, Mengozzi, Alessandro, Menichetti, Francesco, Meschiari, Marianna, Milic, Jovana, Minutolo, Filippo, Molena, Beatrice, Mussini, Cristina, Musso, Maria, Odone, Anna, Olivieri, Marco, Palimodde, Antonella, Pasi, Emanuela, Pesavento, Raffaele, Petri, Francesco, Pinchera, Biagio, Pivato, Carlo A., Poletti, Venerino, Ravaglia, Claudia, Rossato, Marco, Rossi, Marianna, Sabena, Anna, Salinaro, Francesco, Sangiovanni, Vincenzo, Sanrocco, Carlo, Scoppettuolo, Giancarlo, Scorzolini, Laura, Sgariglia, Raffaella, Simeone, Paola Giustina, Trecarichi, Enrico Maria, Vettor, Roberto, Vianello, Andrea, Vinceti, Marco, Virano, Alexandra, Vocciante, Laura, De Caterina, Raffaele, and Iacoviello, Licia

Published
2020
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13. ICT-Supported Interventions Targeting Pre-frailty: Healthcare Recommendations from the Personalised ICT Supported Service for Independent Living and Active Ageing (PERSSILAA) Study

Author

O’Caoimh, Rónán, Molloy, D. William, Fitzgerald, Carol, Van Velsen, Lex, Cabrita, Miriam, Nassabi, Mohammad Hossein, de Vette, Frederiek, van Weering, Marit Dekker, Jansen-Kosterink, Stephanie, Kenter, Wander, Frazer, Sanne, Rauter, Amélia P., Turkman, Antónia, Antunes, Marília, Turkman, Feridun, Silva, Marta S., Martins, Alice, Costa, Helena S., Albuquerque, Tânia Gonçalves, Ferreira, António, Scherillo, Mario, De Luca, Vincenzo, Abete, Pasquale, Colao, Annamaria, García-Rudolph, Alejandro, Sanchez-Carrion, Rocío, Sánchez, Javier Solana, Gomez Aguilera, Enrique J., Illario, Maddalena, Hermens, Hermie, Vollenbroek-Hutten, Miriam, Barbosa, Simone Diniz Junqueira, Series Editor, Filipe, Joaquim, Series Editor, Kotenko, Igor, Series Editor, Sivalingam, Krishna M., Series Editor, Washio, Takashi, Series Editor, Yuan, Junsong, Series Editor, Zhou, Lizhu, Series Editor, Ghosh, Ashish, Series Editor, Röcker, Carsten, editor, O’Donoghue, John, editor, Ziefle, Martina, editor, Maciaszek, Leszek, editor, and Molloy, William, editor

Published
2018
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17. Prevention of cardiovascular complications in elderly cancer patients

Author

Topa, Ester, Rizza, Marika, Iengo, Martina, Cuomo, Alessandra, Cicia, Lidia, Di Sarro, Elena, Miccio, Mattia, Ciaccio, Giuseppe, Luise, Maria Cristina, Formisano, Luigi, Bianco, Roberto, Carlomagno, Chiara, Picardi, Marco, Martinelli, Erika, Napolitano, Stefania, Troiani, Teresa, Ferrara, Nicola, Abete, Pasquale, Tocchetti, Carlo Gabriele, and Mercurio, Valentina

Published
2024
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23. The Italian version of the quick mild cognitive impairment (Qmci-I) screen: normative study on 307 healthy subjects

Author

Iavarone, Alessandro, Carpinelli Mazzi, Michele, Russo, Gennaro, D’Anna, Francesco, Peluso, Silvio, Mazzeo, Pietro, De Luca, Vincenzo, De Michele, Giuseppe, Iaccarino, Guido, Abete, Pasquale, Milan, Graziella, Garofalo, Elisabetta, Musella, Caterina, O’Caoimh, Rónán, Molloy, William, De Joanna, Gabriella, Manzo, Valentino, Ambra, Ferdinando Ivano, Postiglione, Alfredo, Illario, Maddalena, and the Working Group

Published
2019
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33. Mildly oxidized low density lipoprotein activates multiple apoptotic signaling pathways in human coronary cells

Author

Napoli, Claudio, Quehenberger, Oswald, De Nigris, Filomena, Abete, Pasquale, Glass, Christopher K, and Palinski, Wulf

Subjects
Atherosclerosis, Cardiovascular, 2.1 Biological and endogenous factors, Aetiology, Apoptosis, Arteriosclerosis, Caspases, Coronary Vessels, Endothelium, Vascular, Enzyme Activation, Genes, bcl-2, Humans, JNK Mitogen-Activated Protein Kinases, Lipoproteins, LDL, Mitogen-Activated Protein Kinases, Muscle, Smooth, Vascular, NF-kappa B, Oxidation-Reduction, Receptors, Tumor Necrosis Factor, Signal Transduction, Transcription Factor AP-1, fas Receptor, oxidized LDL, atherosclerosis, FasL, TNF receptors, caspases, MAPK, JunK, Biochemistry and Cell Biology, Physiology, Medical Physiology, Biochemistry & Molecular Biology
Abstract

Apoptosis of arterial cells induced by oxidized low density lipoproteins (OxLDL) is thought to contribute to the progression of atherosclerosis. However, most data on apoptotic effects and mechanisms of OxLDL were obtained with extensively oxidized LDL unlikely to occur in early stages of atherosclerotic lesions. We now demonstrate that mildly oxidized LDL generated by incubation with oxygen radical-producing xanthine/xanthine oxidase (X/XO) induces apoptosis in primary cultures of human coronary endothelial and SMC, as determined by TUNEL technique, DNA laddering, and FACS analysis. Apoptosis was markedly reduced when X/XO-LDL was generated in the presence of different oxygen radical scavengers. Apoptotic signals were mediated by intramembrane domains of both Fas and tumor necrosis factor (TNF) receptors I and II. Blocking of Fas ligand (FasL) reduced apoptosis by 50% and simultaneous blocking of FasL and TNF receptors by 70%. Activation of apoptotic receptors was accompanied by an increase of proapoptotic and a decrease in antiapoptotic proteins of the Bcl-2 family and resulted in marked activation of class I and II caspases. Mildly oxidized LDL also activated MAP and Jun kinases and increased p53 and other transcription factors (ATF-2, ELK-1, CREB, AP-1). Inhibitors of Map and Jun kinase significantly reduced apoptosis. Our results provide the first evidence that OxLDL-induced apoptosis involves TNF receptors and Jun activation. More important, they demonstrate that even mildly oxidized LDL formed in atherosclerotic lesions may activate a broad cascade of oxygen radical-sensitive signaling pathways affecting apoptosis and other processes influencing the evolution of plaques. Thus, we suggest that extensive oxidative modifications of LDL are not necessary to influence signal transduction and transcription in vivo.

Published
2000

39. Germline rare variants of lectin pathway genes predispose to asymptomatic SARS-CoV-2 infection in elderly individuals

Author

D’Alterio, Giuseppe, primary, Lasorsa, Vito Alessandro, additional, Bonfiglio, Ferdinando, additional, Cantalupo, Sueva, additional, Rosato, Barbara Eleni, additional, Andolfo, Immacolata, additional, Russo, Roberta, additional, Esposito, Umberto, additional, Frisso, Giulia, additional, Abete, Pasquale, additional, Cassese, Gian Marco, additional, Servillo, Giuseppe, additional, Gentile, Ivan, additional, Piscopo, Carmelo, additional, Della Monica, Matteo, additional, Fiorentino, Giuseppe, additional, Boccia, Angelo, additional, Paolella, Giovanni, additional, Ferrucci, Veronica, additional, de Antonellis, Pasqualino, additional, Siciliano, Roberto, additional, Asadzadeh, Fathem, additional, Cerino, Pellegrino, additional, Buonerba, Carlo, additional, Pierri, Biancamaria, additional, Zollo, Massimo, additional, Iolascon, Achille, additional, and Capasso, Mario, additional

Published
2022
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41. Mild Stress and Healthy Aging: Perspectives for Human Beings

Author

Abete, Pasquale, Calabrese, Edward J., Ji, Li Li, Kristensen, Torsten N., Le Bourg, Eric, Loeschcke, Volker, Morris, Brian J., Rengo, Franco, Rattan, Suresh I. S., Safwat, Akmal, Sørensen, Jesper G., Sarup, Pernille, Vaiserman, Alexander M., Le Bourg, Eric, editor, and Rattan, Suresh I. S., editor

Published
2008
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47. Syncope in the elderly: An update

Author

Pirozzi, Gilda, Ferro, Gaetana, Langellotto, Assunta, Della-Morte, David, Galizia, Gianlugi, Gargiulo, Gaetano, Cacciatore, Francesco, Ungar, Andrea, and Abete, Pasquale

Published
2013
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48. Association between hospitalization-related outcomes, dynapenia and body mass index: The Glisten Study

Author

Rossi, Andrea P, Fantin, Francesco, Abete, Pasquale, Bellelli, Giuseppe, Bo, Mario, Cherubini, Antonio, and Corica, Francesco

Subjects
Obesity -- Risk factors, Hospitalization -- Health aspects, Body mass index -- Analysis -- Health aspects, Activities of daily living, Hospital admission and discharge, Hospital patients, Exercise, Physical fitness, Gerontology, Comorbidity, Food/cooking/nutrition, Health
Abstract

Objective To compare the prognostic value of dynapenia, as evaluated by handgrip, and body mass index (BMI) on length of stay (LOS), days of bed rest, and other hospitalization-related outcomes in a population of older adults admitted to 12 italian acute care divisions. Methods Data on age, weight, BMI, comorbidities, ADL, physical activity level, muscle strength, were recorded at hospital admission. LOS, days of bed rest, intrahospital falls, and discharge destination were also recorded during the hospitalization. Subjects with BMI Results A total of 634 patients, mean age 80.8 [plus or minus] 6.7 years and 49.4% women, were included in the analysis. Overall dynapenic subjects (D) showed a longer period of LOS and bed rest compared with non-dynapenic (ND). When the study population was divided according to BMI categories, underweight (UW), normal weight (NW), and overweight-obese (OW-OB), no significant differences were observed in hospital LOS and days of bed rest. When analysis of covariance was used to determine the difference of LOS across handgrip/BMI groups, D/OW-OB and D/UW subjects showed significantly longer LOS (11.32 and 10.96 days, both p 0.05) compared to ND/NW subjects (7.69 days), even when controlling for age, gender, baseline ADL, cause of hospitalization and comorbidity. After controlling for the same confounding factors, D/OW-OB, D/NW and D/UW subjects showed significantly longer bed rest (4.7, 4.56, and 4.05 days, respectively, all p 0.05, but D/OW-OB p 0.01) compared to ND/NW subjects (1.59 days). Conclusion In our study population, LOS is longer in D/UW and D/OW-OB compared to ND/NW subjects and days of bed rest are mainly influenced by dynapenia, and not by BMI class., Author(s): Andrea P Rossi [sup.1] , Francesco Fantin [sup.1] , Pasquale Abete [sup.2] , Giuseppe Bellelli [sup.3] , Mario Bo [sup.4] , Antonio Cherubini [sup.5] , Francesco Corica [sup.6] , [...]

Published
2019
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50. Personal protective equipment in Covid-19: Evidence-based quality and analysis of YouTube videos after one year of pandemic

Author

Gerundo, Gerardo, primary, Collà Ruvolo, Claudia, additional, Puzone, Brunella, additional, Califano, Gianluigi, additional, La Rocca, Roberto, additional, Parisi, Valentina, additional, Capece, Marco, additional, Celentano, Giuseppe, additional, Creta, Massimiliano, additional, Rengo, Giuseppe, additional, Leosco, Dario, additional, Abete, Pasquale, additional, Longo, Nicola, additional, Mirone, Vincenzo, additional, and Ferrara, Nicola, additional

Published
2022
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