There are many Cassia species which are used in preparing diverse range of herbal products. As per the necessity the present review study reports that Cassia fistula used as medicinal plant for curig various critical diseases. Cassia fistula belong Caesalpinaceae family, commonly known Bandarlati or Sondal. The plant generally grows in India, Bangladesh, Sri Lanka, China, Nepal, Malaysia, Afghanistan, Indonesia, Bhutan and Thailand. From ancient time it is used in various traditional medicinal systems. It is used as anti-cancer, anti-pyretic, ant-diabetic, and analgesic agent. The plant parts are the vital source of plant secondary metabolites such as polyphenols, flavonoids, terpenoids, saponins, anthraquinones, tannin, alkaloid and steroids. The fruits, flower, seed, stem, and leaves of the plant carry these bioactive compounds. These phytochemiclas are effective for the medicinal properties of the plant. The entire plant or its important parts are used for treating the multiple diseases like COVID-19, oxidative stresses, cancer, tumour, microbial infections, swellings, and HIV. The focus of this review article is to highlight the several important botanical, phytochemical and medicinal aspects of Cassia fistula to the entire research communities