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347 results on '"Abraham, John M."'

6. Induced Pluripotent Stem Cell‐Derived Extracellular Vesicles Promote Wound Repair in a Diabetic Mouse Model via an Anti‐Inflammatory Immunomodulatory Mechanism

Author

Levy, Daniel, primary, Abadchi, Sanaz Nourmohammadi, additional, Shababi, Niloufar, additional, Ravari, Mohsen Rouhani, additional, Pirolli, Nicholas H., additional, Bergeron, Cade, additional, Obiorah, Angel, additional, Mokhtari‐Esbuie, Farzad, additional, Gheshlaghi, Shayan, additional, Abraham, John M., additional, Smith, Ian M., additional, Powsner, Emily H., additional, Solomon, Talia J., additional, Harmon, John W., additional, and Jay, Steven M., additional

Published
2023
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8. Supplementary Table S1 from Hypermethylation of Tachykinin-1 Is a Potential Biomarker in Human Esophageal Cancer

Author

Jin, Zhe, primary, Olaru, Alexandru, primary, Yang, Jian, primary, Sato, Fumiaki, primary, Cheng, Yulan, primary, Kan, Takatsugu, primary, Mori, Yuriko, primary, Mantzur, Carmit, primary, Paun, Bogdan, primary, Hamilton, James P., primary, Ito, Tetsuo, primary, Wang, Suna, primary, David, Stefan, primary, Agarwal, Rachana, primary, Beer, David G., primary, Abraham, John M., primary, and Meltzer, Stephen J., primary

Published
2023
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9. Supplementary Tables S1 & S2 from Reprimo Methylation Is a Potential Biomarker of Barrett's-Associated Esophageal Neoplastic Progression

Author

Hamilton, James P., primary, Sato, Fumiaki, primary, Jin, Zhe, primary, Greenwald, Bruce D., primary, Ito, Tetsuo, primary, Mori, Yuriko, primary, Paun, Bogdan C., primary, Kan, Takatsugu, primary, Cheng, Yulan, primary, Wang, Suna, primary, Yang, Jian, primary, Abraham, John M., primary, and Meltzer, Stephen J., primary

Published
2023
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10. Supplementary Data from Methylation Biomarker Panel Performance in EsophaCap Cytology Samples for Diagnosing Barrett's Esophagus: A Prospective Validation Study

Author

Wang, Zhixiong, primary, Kambhampati, Swetha, primary, Cheng, Yulan, primary, Ma, Ke, primary, Simsek, Cem, primary, Tieu, Alan H., primary, Abraham, John M., primary, Liu, Xi, primary, Prasath, Vishnu, primary, Duncan, Mark, primary, Stark, Alejandro, primary, Trick, Alexander, primary, Tsai, Hua-Ling, primary, Wang, Hao, primary, He, Yulong, primary, Khashab, Mouen A., primary, Ngamruengphong, Saowanee, primary, Shin, Eun J., primary, Wang, Tza-Huei, primary, and Meltzer, Stephen J., primary

Published
2023
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11. Supplementary Figure S1 from Reprimo Methylation Is a Potential Biomarker of Barrett's-Associated Esophageal Neoplastic Progression

Author

Hamilton, James P., primary, Sato, Fumiaki, primary, Jin, Zhe, primary, Greenwald, Bruce D., primary, Ito, Tetsuo, primary, Mori, Yuriko, primary, Paun, Bogdan C., primary, Kan, Takatsugu, primary, Cheng, Yulan, primary, Wang, Suna, primary, Yang, Jian, primary, Abraham, John M., primary, and Meltzer, Stephen J., primary

Published
2023
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12. Supplementary Table 1 from A Multicenter, Double-Blinded Validation Study of Methylation Biomarkers for Progression Prediction in Barrett's Esophagus

Author

Jin, Zhe, primary, Cheng, Yulan, primary, Gu, Wen, primary, Zheng, Yingye, primary, Sato, Fumiaki, primary, Mori, Yuriko, primary, Olaru, Alexandru V., primary, Paun, Bogdan C., primary, Yang, Jian, primary, Kan, Takatsugu, primary, Ito, Tetsuo, primary, Hamilton, James P., primary, Selaru, Florin M., primary, Agarwal, Rachana, primary, David, Stefan, primary, Abraham, John M., primary, Wolfsen, Herbert C., primary, Wallace, Michael B., primary, Shaheen, Nicholas J., primary, Washington, Kay, primary, Wang, Jean, primary, Canto, Marcia Irene, primary, Bhattacharyya, Achyut, primary, Nelson, Mark A., primary, Wagner, Paul D., primary, Romero, Yvonne, primary, Wang, Kenneth K., primary, Feng, Ziding, primary, Sampliner, Richard E., primary, and Meltzer, Stephen J., primary

Published
2023
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13. Supplementary Table 1 from Activin Type II Receptor Restoration in ACVR2-Deficient Colon Cancer Cells Induces Transforming Growth Factor-β Response Pathway Genes

Author

Deacu, Elena, primary, Mori, Yuriko, primary, Sato, Fumiaki, primary, Yin, Jing, primary, Olaru, Andreea, primary, Sterian, Anca, primary, Xu, Yan, primary, Wang, Suna, primary, Schulmann, Karsten, primary, Berki, Agnes, primary, Kan, Takatsugu, primary, Abraham, John M., primary, and Meltzer, Stephen J., primary

Published
2023
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14. Supplementary Figure 1 Legend from Activin Type II Receptor Restoration in ACVR2-Deficient Colon Cancer Cells Induces Transforming Growth Factor-β Response Pathway Genes

Author

Deacu, Elena, primary, Mori, Yuriko, primary, Sato, Fumiaki, primary, Yin, Jing, primary, Olaru, Andreea, primary, Sterian, Anca, primary, Xu, Yan, primary, Wang, Suna, primary, Schulmann, Karsten, primary, Berki, Agnes, primary, Kan, Takatsugu, primary, Abraham, John M., primary, and Meltzer, Stephen J., primary

Published
2023
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15. Supplementary Table 3 from A Multicenter, Double-Blinded Validation Study of Methylation Biomarkers for Progression Prediction in Barrett's Esophagus

Author

Jin, Zhe, primary, Cheng, Yulan, primary, Gu, Wen, primary, Zheng, Yingye, primary, Sato, Fumiaki, primary, Mori, Yuriko, primary, Olaru, Alexandru V., primary, Paun, Bogdan C., primary, Yang, Jian, primary, Kan, Takatsugu, primary, Ito, Tetsuo, primary, Hamilton, James P., primary, Selaru, Florin M., primary, Agarwal, Rachana, primary, David, Stefan, primary, Abraham, John M., primary, Wolfsen, Herbert C., primary, Wallace, Michael B., primary, Shaheen, Nicholas J., primary, Washington, Kay, primary, Wang, Jean, primary, Canto, Marcia Irene, primary, Bhattacharyya, Achyut, primary, Nelson, Mark A., primary, Wagner, Paul D., primary, Romero, Yvonne, primary, Wang, Kenneth K., primary, Feng, Ziding, primary, Sampliner, Richard E., primary, and Meltzer, Stephen J., primary

Published
2023
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16. Data from Activin Type II Receptor Restoration in ACVR2-Deficient Colon Cancer Cells Induces Transforming Growth Factor-β Response Pathway Genes

Author

Deacu, Elena, primary, Mori, Yuriko, primary, Sato, Fumiaki, primary, Yin, Jing, primary, Olaru, Andreea, primary, Sterian, Anca, primary, Xu, Yan, primary, Wang, Suna, primary, Schulmann, Karsten, primary, Berki, Agnes, primary, Kan, Takatsugu, primary, Abraham, John M., primary, and Meltzer, Stephen J., primary

Published
2023
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17. Supplementary Figure 2 from A Multicenter, Double-Blinded Validation Study of Methylation Biomarkers for Progression Prediction in Barrett's Esophagus

Author

Jin, Zhe, primary, Cheng, Yulan, primary, Gu, Wen, primary, Zheng, Yingye, primary, Sato, Fumiaki, primary, Mori, Yuriko, primary, Olaru, Alexandru V., primary, Paun, Bogdan C., primary, Yang, Jian, primary, Kan, Takatsugu, primary, Ito, Tetsuo, primary, Hamilton, James P., primary, Selaru, Florin M., primary, Agarwal, Rachana, primary, David, Stefan, primary, Abraham, John M., primary, Wolfsen, Herbert C., primary, Wallace, Michael B., primary, Shaheen, Nicholas J., primary, Washington, Kay, primary, Wang, Jean, primary, Canto, Marcia Irene, primary, Bhattacharyya, Achyut, primary, Nelson, Mark A., primary, Wagner, Paul D., primary, Romero, Yvonne, primary, Wang, Kenneth K., primary, Feng, Ziding, primary, Sampliner, Richard E., primary, and Meltzer, Stephen J., primary

Published
2023
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18. Supplementary Figure Legends 1-2 from A Multicenter, Double-Blinded Validation Study of Methylation Biomarkers for Progression Prediction in Barrett's Esophagus

Author

Jin, Zhe, primary, Cheng, Yulan, primary, Gu, Wen, primary, Zheng, Yingye, primary, Sato, Fumiaki, primary, Mori, Yuriko, primary, Olaru, Alexandru V., primary, Paun, Bogdan C., primary, Yang, Jian, primary, Kan, Takatsugu, primary, Ito, Tetsuo, primary, Hamilton, James P., primary, Selaru, Florin M., primary, Agarwal, Rachana, primary, David, Stefan, primary, Abraham, John M., primary, Wolfsen, Herbert C., primary, Wallace, Michael B., primary, Shaheen, Nicholas J., primary, Washington, Kay, primary, Wang, Jean, primary, Canto, Marcia Irene, primary, Bhattacharyya, Achyut, primary, Nelson, Mark A., primary, Wagner, Paul D., primary, Romero, Yvonne, primary, Wang, Kenneth K., primary, Feng, Ziding, primary, Sampliner, Richard E., primary, and Meltzer, Stephen J., primary

Published
2023
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19. Supplementary Table 2 from A Multicenter, Double-Blinded Validation Study of Methylation Biomarkers for Progression Prediction in Barrett's Esophagus

Author

Jin, Zhe, primary, Cheng, Yulan, primary, Gu, Wen, primary, Zheng, Yingye, primary, Sato, Fumiaki, primary, Mori, Yuriko, primary, Olaru, Alexandru V., primary, Paun, Bogdan C., primary, Yang, Jian, primary, Kan, Takatsugu, primary, Ito, Tetsuo, primary, Hamilton, James P., primary, Selaru, Florin M., primary, Agarwal, Rachana, primary, David, Stefan, primary, Abraham, John M., primary, Wolfsen, Herbert C., primary, Wallace, Michael B., primary, Shaheen, Nicholas J., primary, Washington, Kay, primary, Wang, Jean, primary, Canto, Marcia Irene, primary, Bhattacharyya, Achyut, primary, Nelson, Mark A., primary, Wagner, Paul D., primary, Romero, Yvonne, primary, Wang, Kenneth K., primary, Feng, Ziding, primary, Sampliner, Richard E., primary, and Meltzer, Stephen J., primary

Published
2023
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20. Supplementary Methods section from Identification of Genes Uniquely Involved in Frequent Microsatellite Instability Colon Carcinogenesis by Expression Profiling Combined with Epigenetic Scanning

Author

Mori, Yuriko, primary, Yin, Jing, primary, Sato, Fumiaki, primary, Sterian, Anca, primary, Simms, Lisa A., primary, Selaru, Florin M., primary, Schulmann, Karsten, primary, Xu, Yan, primary, Olaru, Andreea, primary, Wang, Suna, primary, Deacu, Elena, primary, Abraham, John M., primary, Young, Joanne, primary, Leggett, Barbara A., primary, and Meltzer, Stephen J., primary

Published
2023
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21. Supplementary Methods from Activin Type II Receptor Restoration in ACVR2-Deficient Colon Cancer Cells Induces Transforming Growth Factor-β Response Pathway Genes

Author

Deacu, Elena, primary, Mori, Yuriko, primary, Sato, Fumiaki, primary, Yin, Jing, primary, Olaru, Andreea, primary, Sterian, Anca, primary, Xu, Yan, primary, Wang, Suna, primary, Schulmann, Karsten, primary, Berki, Agnes, primary, Kan, Takatsugu, primary, Abraham, John M., primary, and Meltzer, Stephen J., primary

Published
2023
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22. Data from A Multicenter, Double-Blinded Validation Study of Methylation Biomarkers for Progression Prediction in Barrett's Esophagus

Author

Jin, Zhe, primary, Cheng, Yulan, primary, Gu, Wen, primary, Zheng, Yingye, primary, Sato, Fumiaki, primary, Mori, Yuriko, primary, Olaru, Alexandru V., primary, Paun, Bogdan C., primary, Yang, Jian, primary, Kan, Takatsugu, primary, Ito, Tetsuo, primary, Hamilton, James P., primary, Selaru, Florin M., primary, Agarwal, Rachana, primary, David, Stefan, primary, Abraham, John M., primary, Wolfsen, Herbert C., primary, Wallace, Michael B., primary, Shaheen, Nicholas J., primary, Washington, Kay, primary, Wang, Jean, primary, Canto, Marcia Irene, primary, Bhattacharyya, Achyut, primary, Nelson, Mark A., primary, Wagner, Paul D., primary, Romero, Yvonne, primary, Wang, Kenneth K., primary, Feng, Ziding, primary, Sampliner, Richard E., primary, and Meltzer, Stephen J., primary

Published
2023
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23. Data from Pituitary Tumor-Transforming 1 Increases Cell Motility and Promotes Lymph Node Metastasis in Esophageal Squamous Cell Carcinoma

Author

Ito, Tetsuo, primary, Shimada, Yutaka, primary, Kan, Takatsugu, primary, David, Stefan, primary, Cheng, Yulan, primary, Mori, Yuriko, primary, Agarwal, Rachana, primary, Paun, Bogdan, primary, Jin, Zhe, primary, Olaru, Alexandru, primary, Hamilton, James P., primary, Yang, Jian, primary, Abraham, John M., primary, Meltzer, Stephen J., primary, and Sato, Fumiaki, primary

Published
2023
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24. Supplementary Figure 1 from A Multicenter, Double-Blinded Validation Study of Methylation Biomarkers for Progression Prediction in Barrett's Esophagus

Author

Jin, Zhe, primary, Cheng, Yulan, primary, Gu, Wen, primary, Zheng, Yingye, primary, Sato, Fumiaki, primary, Mori, Yuriko, primary, Olaru, Alexandru V., primary, Paun, Bogdan C., primary, Yang, Jian, primary, Kan, Takatsugu, primary, Ito, Tetsuo, primary, Hamilton, James P., primary, Selaru, Florin M., primary, Agarwal, Rachana, primary, David, Stefan, primary, Abraham, John M., primary, Wolfsen, Herbert C., primary, Wallace, Michael B., primary, Shaheen, Nicholas J., primary, Washington, Kay, primary, Wang, Jean, primary, Canto, Marcia Irene, primary, Bhattacharyya, Achyut, primary, Nelson, Mark A., primary, Wagner, Paul D., primary, Romero, Yvonne, primary, Wang, Kenneth K., primary, Feng, Ziding, primary, Sampliner, Richard E., primary, and Meltzer, Stephen J., primary

Published
2023
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25. Supplementary Table 1 from Identification of Genes Uniquely Involved in Frequent Microsatellite Instability Colon Carcinogenesis by Expression Profiling Combined with Epigenetic Scanning

Author

Mori, Yuriko, primary, Yin, Jing, primary, Sato, Fumiaki, primary, Sterian, Anca, primary, Simms, Lisa A., primary, Selaru, Florin M., primary, Schulmann, Karsten, primary, Xu, Yan, primary, Olaru, Andreea, primary, Wang, Suna, primary, Deacu, Elena, primary, Abraham, John M., primary, Young, Joanne, primary, Leggett, Barbara A., primary, and Meltzer, Stephen J., primary

Published
2023
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26. Supplementary Table 2 from Activin Type II Receptor Restoration in ACVR2-Deficient Colon Cancer Cells Induces Transforming Growth Factor-β Response Pathway Genes

Author

Deacu, Elena, primary, Mori, Yuriko, primary, Sato, Fumiaki, primary, Yin, Jing, primary, Olaru, Andreea, primary, Sterian, Anca, primary, Xu, Yan, primary, Wang, Suna, primary, Schulmann, Karsten, primary, Berki, Agnes, primary, Kan, Takatsugu, primary, Abraham, John M., primary, and Meltzer, Stephen J., primary

Published
2023
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27. Supplementary Table 2 from Identification of Genes Uniquely Involved in Frequent Microsatellite Instability Colon Carcinogenesis by Expression Profiling Combined with Epigenetic Scanning

Author

Mori, Yuriko, primary, Yin, Jing, primary, Sato, Fumiaki, primary, Sterian, Anca, primary, Simms, Lisa A., primary, Selaru, Florin M., primary, Schulmann, Karsten, primary, Xu, Yan, primary, Olaru, Andreea, primary, Wang, Suna, primary, Deacu, Elena, primary, Abraham, John M., primary, Young, Joanne, primary, Leggett, Barbara A., primary, and Meltzer, Stephen J., primary

Published
2023
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28. Data from Identification of Genes Uniquely Involved in Frequent Microsatellite Instability Colon Carcinogenesis by Expression Profiling Combined with Epigenetic Scanning

Author

Mori, Yuriko, primary, Yin, Jing, primary, Sato, Fumiaki, primary, Sterian, Anca, primary, Simms, Lisa A., primary, Selaru, Florin M., primary, Schulmann, Karsten, primary, Xu, Yan, primary, Olaru, Andreea, primary, Wang, Suna, primary, Deacu, Elena, primary, Abraham, John M., primary, Young, Joanne, primary, Leggett, Barbara A., primary, and Meltzer, Stephen J., primary

Published
2023
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29. Supplementary Figure 1 from Activin Type II Receptor Restoration in ACVR2-Deficient Colon Cancer Cells Induces Transforming Growth Factor-β Response Pathway Genes

Author

Deacu, Elena, primary, Mori, Yuriko, primary, Sato, Fumiaki, primary, Yin, Jing, primary, Olaru, Andreea, primary, Sterian, Anca, primary, Xu, Yan, primary, Wang, Suna, primary, Schulmann, Karsten, primary, Berki, Agnes, primary, Kan, Takatsugu, primary, Abraham, John M., primary, and Meltzer, Stephen J., primary

Published
2023
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30. Supplementary Table 4 from A Multicenter, Double-Blinded Validation Study of Methylation Biomarkers for Progression Prediction in Barrett's Esophagus

Author

Jin, Zhe, primary, Cheng, Yulan, primary, Gu, Wen, primary, Zheng, Yingye, primary, Sato, Fumiaki, primary, Mori, Yuriko, primary, Olaru, Alexandru V., primary, Paun, Bogdan C., primary, Yang, Jian, primary, Kan, Takatsugu, primary, Ito, Tetsuo, primary, Hamilton, James P., primary, Selaru, Florin M., primary, Agarwal, Rachana, primary, David, Stefan, primary, Abraham, John M., primary, Wolfsen, Herbert C., primary, Wallace, Michael B., primary, Shaheen, Nicholas J., primary, Washington, Kay, primary, Wang, Jean, primary, Canto, Marcia Irene, primary, Bhattacharyya, Achyut, primary, Nelson, Mark A., primary, Wagner, Paul D., primary, Romero, Yvonne, primary, Wang, Kenneth K., primary, Feng, Ziding, primary, Sampliner, Richard E., primary, and Meltzer, Stephen J., primary

Published
2023
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32. Induced Pluripotent Stem Cell-Derived Extracellular Vesicles Promote Wound Repair in a Diabetic Mouse Model via an Anti-Inflammatory Immunomodulatory Mechanism

Author

Levy, Daniel, Levy, Daniel, Abadchi, Sanaz Nourhammadi, Shababi, Niloufar, Ravari, Mohsen Rouhani, Pirolli, Nicholas H., Bergeron, Cade, Obiorah, Angel, Mokhtari-Esbuie, Farzad, Gheshlaghi, Shayan, Abraham, John M., Smith, Ian M., Powsner, Emily H., Solomon, Talia J., Harmon, John W., Jay, Steven M., Levy, Daniel, Levy, Daniel, Abadchi, Sanaz Nourhammadi, Shababi, Niloufar, Ravari, Mohsen Rouhani, Pirolli, Nicholas H., Bergeron, Cade, Obiorah, Angel, Mokhtari-Esbuie, Farzad, Gheshlaghi, Shayan, Abraham, John M., Smith, Ian M., Powsner, Emily H., Solomon, Talia J., Harmon, John W., and Jay, Steven M.

Abstract

Extracellular vesicles (EVs) derived from mesenchymal stem/stromal cells (MSCs) have recently been explored in clinical trials for treatment of diseases with complex pathophysiologies. However, production of MSC EVs is currently hampered by donor-specific characteristics and limited ex vivo expansion capabilities before decreased potency, thus restricting their potential as a scalable and reproducible therapeutic. Induced pluripotent stem cells (iPSCs) represent a self-renewing source for obtaining differentiated iPSC-derived MSCs (iMSCs), circumventing both scalability and donor variability concerns for therapeutic EV production. Thus, it is initially sought to evaluate the therapeutic potential of iMSC EVs. Interestingly, while utilizing undifferentiated iPSC EVs as a control, it is found that their vascularization bioactivity is similar and their anti-inflammatory bioactivity is superior to donor-matched iMSC EVs in cell-based assays. To supplement this initial in vitro bioactivity screen, a diabetic wound healing mouse model where both the pro-vascularization and anti-inflammatory activity of these EVs would be beneficial is employed. In this in vivo model, iPSC EVs more effectively mediate inflammation resolution within the wound bed. Combined with the lack of additional differentiation steps required for iMSC generation, these results support the use of undifferentiated iPSCs as a source for therapeutic EV production with respect to both scalability and efficacy.

Published
2023

33. Novel Silencing RNA Strategy for Pancreatic Cancer

Author

Pippenger, Emma K, primary, Chang, Kai, additional, Abadchi, Sanaz Nourmohammadi, additional, Leng, Albert, additional, Halami, Bhaskar, additional, Lu, Xiaoyong, additional, Johnson, Christopher R, additional, Abraham, John M, additional, Ha, Jinny, additional, and Harmon, John W, additional

Published
2022
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40. Novel Long Noncoding RNA miR205HG Functions as an Esophageal Tumor-Suppressive Hedgehog Inhibitor

Author

Song, Jee Hoon, primary, Tieu, Alan H., additional, Cheng, Yulan, additional, Ma, Ke, additional, Akshintala, Venkata S., additional, Simsek, Cem, additional, Prasath, Vishnu, additional, Shin, Eun Ji, additional, Ngamruengphong, Saowanee, additional, Khashab, Mouen A., additional, Abraham, John M., additional, and Meltzer, Stephen J., additional

Published
2021
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