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2. Particle tracer transport in a sloping soil lysimeter under periodic, steady state conditions

Author

Wang, C, McNew, CP, Lyon, SW, Walter, MT, Volkman, THM, Abramson, N, Sengupta, A, Wang, Y, Meira Neto, AA, Pangle, L, Troch, PA, Kim, M, Harman, C, and Dahlke, HE

Subjects
Colloid, Transport, Vadose zone, Tracer, Transient, Unsaturated, Environmental Engineering
Abstract

Colloid transport through complex and dynamic (i.e. non-steady-state) hydrologic systems is rarely studied, owing to the difficulty of constraining initial and boundary conditions and quantifying colloid-porous media and colloid-colloid interactions in transient flow systems. Here we present a particle tracer experiment conducted on a sloped lysimeter receiving periodic rainfall events for 10 days. Four unique, DNA-labelled particle tracers were injected both in sequence and in parallel, together with a conservative tracer (deuterium), over the course of the first day and allowed to move through the system. Discharge-particle tracer concentration curves and the spatial distribution of particle tracer mass retained in the soil at the end of the experiment were found to be highly dependent on the timing of the tracer injection and the precipitation input and subsequent dynamic response of the water table. Overall, neglecting the total DLT recovery rate, the DLT particle tracer breakthrough trend (DNA-labelled particle tracer 4) was similar to deuterium and decreased over time with the exception of a few peaks later in the experiment. The individual particle tracer breakthrough curves suggest a complex system with different fast transport mechanisms (e.g. capillary barrier and size exclusion effect) and slow retention-release mechanisms (e.g. straining, physical-chemical adsorption), which resulted in particle tracers transferring faster than deuterium in the first 10 h of the experiment but being exceeded by deuterium soon after deuterium started to break through. The experiment not only highlights the interaction of repeated colloidal pollution events in hydrologic systems with different pre-event saturation conditions, but also the benefits of using multiple synchronous or sequential tracer applications to dissect explicit formulations of water flow and colloid transport processes in complex and dynamic hydrological systems. Such explicit process formulations could help improve understanding hydrologically-controlled transport through catchments and the quantitative prediction of these processes with water quality models.

Published
2019

6. Lipid Profiles, Inflammatory Markers, and Insulin Therapy in Youth with Type 2 Diabetes

Author

McKay, S., Haymond, M., Anderson, B., Bush, C., Gunn, S., Holden, H., Jones, S.M., Jeha, G., McGirk, S., Thamotharan, S., Cuttler, L., Abrams, E., Casey, T., Dahms, W., Ievers-Landis, C., Kaminski, B., Koontz, M., MacLeish, S., McGuigan, P., Narasimhan, S., Geffner, M., Barraza, V., Chang, N., Conrad, B., Dreimane, D., Estrada, S., Fisher, L., Fleury-Milfort, E., Hernandez, S., Hollen, B., Kaufman, F., Law, E., Mansilla, V., Miller, D., Muñoz, C., Ortiz, R., Ward, A., Wexler, K., Xu, Y.K., Yasuda, P., Berkowitz, R., Boyd, S., Johnson, B., Kaplan, J., Keating, C., Lassiter, C., Lipman, T., McGinley, G., McKnight, H., Schwartzman, B., Willi, S., Arslanian, S., Foster, S., Galvin, B., Hannon, T., Kriska, A., Marcus, M., Songer, T., Venditti, E., Goland, R., Gallagher, D., Kringas, P., Leibel, N., Ng, D., Ovalles, M., Seidman, D., Laffel, L., Goebel-Fabbri, A., Hall, M., Higgins, L., Keady, J., Malloy, M., Milaszewski, K., Rasbach, L., Nathan, D.M., Angelescu, A., Bissett, L., Ciccarelli, C., Delahanty, L., Goldman, V., Hardy, O., Larkin, M., Levitsky, L., McEachern, R., Norman, D., Nwosu, D., Park-Bennett, S., Richards, D., Sherry, N., Steiner, B., Tollefsen, S., Carnes, S., Dempsher, D., Flomo, D., Whelan, T., Wolff, B., Bowerman, D., Bristol, S., Bulger, J., Hartsig, J., Izquierdo, R., Kearns, J., Saletsky, R., Trief, P., Zeitler, P., Abramson, N., Bradhurst, A., Celona-Jacobs, N., Higgins, J., Kelsey, M., Klingensmith, G., Witten, T., Copeland, K., Boss, E., Brown, R., Chadwick, J., Chalmers, L., Chernausek, S., Hebensperger, A., Macha, C., Newgent, R., Nordyke, A., Olson, D., Poulsen, T., Pratt, L., Preske, J., Schanuel, J., Sternlof, S., Lynch, J., Amodei, N., Barajas, R., Cody, C., Hale, D., Hernandez, J., Ibarra, C., Morales, E., Rivera, S., Rupert, G., Wauters, A., White, N., Arbeláez, A., Jones, J., Jones, T., Sadler, M., Tanner, M., Timpson, A., Welch, R., Caprio, S., Grey, M., Guandalini, C., Lavietes, S., Rose, P., Syme, A., Tamborlane, W., Hirst, K., Edelstein, S., Feit, P., Grover, N., Long, C., Pyle, L., Linder, B., Harting, J., Shepherd, J., Fan, B., Marquez, L., Sherman, M., Wang, J., Nichols, M., Mayer-Davis, E., Liu, Y., Lima, J., Puccella, J., Ricketts, E., Danis, R., Domalpally, A., Goulding, A., Neill, S., Vargo, P., Wilfley, D., Aldrich-Rasche, D., Franklin, K., Massmann, C., O'Brien, D., Patterson, J., Tibbs, T., Van Buren, D., Palmert, M., Ratner, R., Dremaine, D., Silverstein, J., Levitt Katz, Lorraine E., Bacha, Fida, Gidding, Samuel S., Weinstock, Ruth S., El ghormli, Laure, Libman, Ingrid, Nadeau, Kristen J., Porter, Kristin, and Marcovina, Santica

Published
2018
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7. Cardiac Biomarkers in Youth with Type 2 Diabetes Mellitus: Results from the TODAY Study

Author

McKay, S., Haymond, M., Anderson, B., Bush, C., Gunn, S., Holden, H., Jones, S.M., Jeha, G., McGirk, S., Thamotharan, S., Cuttler, L., Abrams, E., Casey, T., Dahms, W., Ievers-Landis, C., Kaminski, B., Koontz, M., MacLeish, S., McGuigan, P., Narasimhan, S., Geffner, M., Barraza, V., Chang, N., Conrad, B., Dreimane, D., Estrada, S., Fisher, L., Fleury-Milfort, E., Hernandez, S., Hollen, B., Kaufman, F., Law, E., Mansilla, V., Miller, D., Muñoz, C., Ortiz, R., Ward, A., Wexler, K., Xu, Y.K., Yasuda, P., Levitt Katz, L., Berkowitz, R., Boyd, S., Johnson, B., Kaplan, J., Keating, C., Lassiter, C., Lipman, T., McGinley, G., McKnight, H., Schwartzman, B., Willi, S., Arslanian, S., Bacha, F., Foster, S., Galvin, B., Hannon, T., Kriska, A., Libman, I., Marcus, M., Porter, K., Songer, T., Venditti, E., Goland, R., Gallagher, D., Kringas, P., Leibel, N., Ng, D., Ovalles, M., Seidman, D., Laffel, L., Goebel-Fabbri, A., Hall, M., Higgins, L., Keady, J., Malloy, M., Milaszewski, K., Rasbach, L., Nathan, D.M., Angelescu, A., Bissett, L., Ciccarelli, C., Delahanty, L., Goldman, V., Hardy, O., Larkin, M., Levitsky, L., McEachern, R., Norman, D., Nwosu, D., Park-Bennett, S., Richards, D., Sherry, N., Steiner, B., Tollefsen, S., Carnes, S., Dempsher, D., Flomo, D., Whelan, T., Wolff, B., Weinstock, R., Bowerman, D., Bristol, S., Bulger, J., Hartsig, J., Izquierdo, R., Kearns, J., Saletsky, R., Trief, P., Zeitler, P., Abramson, N., Bradhurst, A., Celona-Jacobs, N., Higgins, J., Kelsey, M., Klingensmith, G., Nadeau, K., Witten, T., Copeland, K., Boss, E., Brown, R., Chadwick, J., Chalmers, L., Chernausek, S., Hebensperger, A., Macha, C., Newgent, R., Nordyke, A., Olson, D., Poulsen, T., Pratt, L., Preske, J., Schanuel, J., Sternlof, S., Lynch, J., Amodei, N., Barajas, R., Cody, C., Hale, D., Hernandez, J., Ibarra, C., Morales, E., Rivera, S., Rupert, G., Wauters, A., White, N., Arbeláez, A., Jones, J., Jones, T., Sadler, M., Tanner, M., Timpson, A., Welch, R., Caprio, S., Grey, M., Guandalini, C., Lavietes, S., Rose, P., Syme, A., Tamborlane, W., Hirst, K., Edelstein, S., Feit, P., Grover, N., Long, C., Pyle, L., Linder, B., Marcovina, S.M., Harting, J., Shepherd, J., Fan, B., Marquez, L., Sherman, M., Wang, J., Nichols, M., Mayer-Davis, E., Liu, Y., Lima, J., Gidding, S., Puccella, J., Ricketts, E., Danis, R., Domalpally, A., Goulding, A., Neill, S., Vargo, P., Wilfley, D., Aldrich-Rasche, D., Franklin, K., Massmann, C., O'Brien, D., Patterson, J., Tibbs, T., Van Buren, D., Palmert, M., Ratner, R., Dremaine, D., Silverstein, J., Gidding, Samuel S., Bacha, Fida, Bjornstad, Petter, Levitt Katz, Lorraine E., Levitsky, Lynne L., Lynch, Jane, Tryggestad, Jeanie B., Weinstock, Ruth S., El ghormli, Laure, and Lima, Joao A.C.

Published
2018
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16. Cardiac Biomarkers in Youth with Type 2 Diabetes Mellitus: Results from the TODAY Study

Author

Gidding, Samuel S., Bacha, Fida, Bjornstad, Petter, Katz, Lorraine E. Levitt, Levitsky, Lynne L., Lynch, Jane, Tryggestad, Jeanie B., Weinstock, Ruth S., El ghormli, Laure, Lima, Joao A.C., McKay, S., Haymond, M., Anderson, B., Bush, C., Gunn, S., Holden, H., Jones, S. M., Jeha, G., McGirk, S., Thamotharan, S., Cuttler, L., Abrams, E., Casey, T., Dahms, W., Ievers-Landis, C., Kaminski, B., Koontz, M., MacLeish, S., McGuigan, P., Narasimhan, S., Geffner, M., Barraza, V., Chang, N., Conrad, B., Dreimane, D., Estrada, S., Fisher, L., Fleury-Milfort, E., Hernandez, S., Hollen, B., Kaufman, F., Law, E., Mansilla, V., Miller, D., Muñoz, C., Ortiz, R., Ward, A., Wexler, K., Xu, Y. K., Yasuda, P., Katz, Levitt L., Berkowitz, R., Boyd, S., Johnson, B., Kaplan, J., Keating, C., Lassiter, C., Lipman, T., McGinley, G., McKnight, H., Schwartzman, B., Willi, S., Arslanian, S., Bacha, F., Foster, S., Galvin, B., Hannon, T., Kriska, A., Libman, I., Marcus, M., Porter, K., Songer, T., Venditti, E., Goland, R., Gallagher, D., Kringas, P., Leibel, N., Ng, D., Ovalles, M., Seidman, D., Laffel, L., Goebel-Fabbri, A., Hall, M., Higgins, L., Keady, J., Malloy, M., Milaszewski, K., Rasbach, L., Nathan, D. M., Angelescu, A., Bissett, L., Ciccarelli, C., Delahanty, L., Goldman, V., Hardy, O., Larkin, M., Levitsky, L., McEachern, R., Norman, D., Nwosu, D., Park-Bennett, S., Richards, D., Sherry, N., Steiner, B., Tollefsen, S., Carnes, S., Dempsher, D., Flomo, D., Whelan, T., Wolff, B., Weinstock, R., Bowerman, D., Bristol, S., Bulger, J., Hartsig, J., Izquierdo, R., Kearns, J., Saletsky, R., Trief, P., Zeitler, P., Abramson, N., Bradhurst, A., Celona-Jacobs, N., Higgins, J., Kelsey, M., Klingensmith, G., Nadeau, K., Witten, T., Copeland, K., Boss, E., Brown, R., Chadwick, J., Chalmers, L., Chernausek, S., Hebensperger, A., Macha, C., Newgent, R., Nordyke, A., Olson, D., Poulsen, T., Pratt, L., Preske, J., Schanuel, J., Sternlof, S., Lynch, J., Amodei, N., Barajas, R., Cody, C., Hale, D., Hernandez, J., Ibarra, C., Morales, E., Rivera, S., Rupert, G., Wauters, A., White, N., Arbeláez, A., Jones, J., Jones, T., Sadler, M., Tanner, M., Timpson, A., Welch, R., Caprio, S., Grey, M., Guandalini, C., Lavietes, S., Rose, P., Syme, A., Tamborlane, W., Hirst, K., Edelstein, S., Feit, P., Grover, N., Long, C., Pyle, L., Linder, B., Marcovina, S. M., Harting, J., Shepherd, J., Fan, B., Marquez, L., Sherman, M., Wang, J., Nichols, M., Mayer-Davis, E., Liu, Y., Lima, J., Gidding, S., Puccella, J., Ricketts, E., Danis, R., Domalpally, A., Goulding, A., Neill, S., Vargo, P., Wilfley, D., Aldrich-Rasche, D., Franklin, K., Massmann, C., O’Brien, D., Patterson, J., Tibbs, T., Van Buren, D., Palmert, M., Ratner, R., Dremaine, D., and Silverstein, J.

Published
2018
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22. Care for Adolescents with PCOS: development and prescribing patterns of a multidisciplinary clinic

Author

Torres-Zegarra, C., Sundararajan, D., Benson, J., Seagle, H., Witten, M., Walders-Abramson, N., Simon, S.L., Huguelet, P., Nokoff, N.J., and Cree-Green, M.

Subjects
Adult, Hirsutism, Young Adult, Adolescent, Humans, Alopecia, Female, Child, Article, Metformin, Polycystic Ovary Syndrome, Retrospective Studies
Abstract

STUDY OBJECTIVE: Based on updated guidelines and expressed patient needs, we created a multidisciplinary clinic including endocrinology, gynecology/adolescent medicine, dermatology, psychology, and nutrition to provide comprehensive care to adolescent girls with polycystic ovary syndrome (PCOS). We describe the patient population presenting to this clinic and prescribing patterns when a multidisciplinary approach is utilized. DESIGN: Retrospective chart review SETTING: Tertiary care hospital PARTICIPANTS: Female patients, ages 11–24 years, presenting for initial assessment in a multidisciplinary PCOS clinic INTERVENTIONS: None MAIN OUTCOME MEASURES: Medical history, physical exam findings, laboratory measurements and prescribed therapies RESULTS: 92 patients seen from 2014–2018 are described (age 15.9 years, range 11–24, BMI 35.6 kg/m(2), range 19.9–53.5). Metabolic syndrome features were common: 26% had a prediabetes hemoglobin A1c (>5.6%), 83% had a high-density lipoprotein (HDL) 120 mmHg, and 43% had an alanine aminotransferase >30 U/L. Dermatologic findings included: acne 93%, hirsutism 38%, acanthosis nigricans 85%, hidradenitis suppurativa 16%, and androgenic alopecia 2%. 33% had a diagnosis of depression or anxiety, 16% of patients had a diagnosis of obstructive sleep apnea, and an additional 59% had symptoms warranting a sleep study The most commonly prescribed medications were topical acne preparations (62%), followed by estrogen-containing hormonal therapy (56%) and metformin (40%). CONCLUSION: In adolescents with PCOS and obesity, metabolic, dermatologic and psychologic co-morbidities are common. The use of a multidisciplinary clinic model including dermatology in addition to endocrinology, gynecology, psychology, and lifestyle experts provides care for most aspects of PCOS.

Published
2021

32. An improved practical approach for estimating catchment-scale response functions through wavelet analysis

Author

Dwivedi, Ravindra, primary, Eastoe, Chris, additional, Knowles, John, additional, Hamann, Lejon, additional, Meixner, Thomas, additional, Ferré, P. “Ty”, additional, Castro, C., additional, Wright, W., additional, Niu, Guo-Yue, additional, Minor, Rebecca, additional, Barron-Gafford, Greg, additional, Abramson, N., additional, Mitra, B., additional, Papuga, Shirley, additional, Stanley, M., additional, and Chorover, Jon, additional

Published
2020
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35. Posters

Author

Nielsen, J., Hansen, E. G., Antonsen, K., Frederiksen, H. J., Lippert, F. K., Bonde, J., Danschutter D., Goris J., Ramet J., Koutsoukou, A., Papadhimitriou, S. I., Kithreotis, P., Stratouli, S., Vlahogiorgos, G., Veldekis, D., Eliopoulos, E., Dexter, T. J., Challant, G., Waldmann, C. S., Bernau, F., Waldmann, C. S., Meanock, C., Thomas, J., Defouilloy, C., Defouilloy, I., Tinturier, F., Magnier, S., Slama, M., Ossart, M., Hofhuis, J., Rommes, J. H., Bakker, J., Roupie, E., Durand-Zaleski, I., Picard, J. Y., Lemaire, F., Pateman, I., Conyers, A. B., Ramet, J., Van Herreweghe, I., Danschutter, D., Spapen, H., Diltoer, M., Huyghens, L., Bouchet, M. F., Wysocki, M., Dejeux, D., Mirarda, D. Reis, Iapichino, G., Moreao, R., Lamb, F. J., Mitchell, I. A., Grounds, R. M., Bennett, E. D., Bihari, D. J., Jacques, T., Angus, D. C., Clermont, G., Lee, K. H., Craig, M. T., Abramson, N. S., ICU nurses, and Brain Resuscitation Clinical Trial III Study Group

Published
1996
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41. Lipid Profiles, Inflammatory Markers, and Insulin Therapy in Youth with Type 2 Diabetes

Author

Levitt Katz, Lorraine E., primary, Bacha, Fida, additional, Gidding, Samuel S., additional, Weinstock, Ruth S., additional, El ghormli, Laure, additional, Libman, Ingrid, additional, Nadeau, Kristen J., additional, Porter, Kristin, additional, Marcovina, Santica, additional, McKay, S., additional, Haymond, M., additional, Anderson, B., additional, Bush, C., additional, Gunn, S., additional, Holden, H., additional, Jones, S.M., additional, Jeha, G., additional, McGirk, S., additional, Thamotharan, S., additional, Cuttler, L., additional, Abrams, E., additional, Casey, T., additional, Dahms, W., additional, Ievers-Landis, C., additional, Kaminski, B., additional, Koontz, M., additional, MacLeish, S., additional, McGuigan, P., additional, Narasimhan, S., additional, Geffner, M., additional, Barraza, V., additional, Chang, N., additional, Conrad, B., additional, Dreimane, D., additional, Estrada, S., additional, Fisher, L., additional, Fleury-Milfort, E., additional, Hernandez, S., additional, Hollen, B., additional, Kaufman, F., additional, Law, E., additional, Mansilla, V., additional, Miller, D., additional, Muñoz, C., additional, Ortiz, R., additional, Ward, A., additional, Wexler, K., additional, Xu, Y.K., additional, Yasuda, P., additional, Berkowitz, R., additional, Boyd, S., additional, Johnson, B., additional, Kaplan, J., additional, Keating, C., additional, Lassiter, C., additional, Lipman, T., additional, McGinley, G., additional, McKnight, H., additional, Schwartzman, B., additional, Willi, S., additional, Arslanian, S., additional, Foster, S., additional, Galvin, B., additional, Hannon, T., additional, Kriska, A., additional, Marcus, M., additional, Songer, T., additional, Venditti, E., additional, Goland, R., additional, Gallagher, D., additional, Kringas, P., additional, Leibel, N., additional, Ng, D., additional, Ovalles, M., additional, Seidman, D., additional, Laffel, L., additional, Goebel-Fabbri, A., additional, Hall, M., additional, Higgins, L., additional, Keady, J., additional, Malloy, M., additional, Milaszewski, K., additional, Rasbach, L., additional, Nathan, D.M., additional, Angelescu, A., additional, Bissett, L., additional, Ciccarelli, C., additional, Delahanty, L., additional, Goldman, V., additional, Hardy, O., additional, Larkin, M., additional, Levitsky, L., additional, McEachern, R., additional, Norman, D., additional, Nwosu, D., additional, Park-Bennett, S., additional, Richards, D., additional, Sherry, N., additional, Steiner, B., additional, Tollefsen, S., additional, Carnes, S., additional, Dempsher, D., additional, Flomo, D., additional, Whelan, T., additional, Wolff, B., additional, Bowerman, D., additional, Bristol, S., additional, Bulger, J., additional, Hartsig, J., additional, Izquierdo, R., additional, Kearns, J., additional, Saletsky, R., additional, Trief, P., additional, Zeitler, P., additional, Abramson, N., additional, Bradhurst, A., additional, Celona-Jacobs, N., additional, Higgins, J., additional, Kelsey, M., additional, Klingensmith, G., additional, Witten, T., additional, Copeland, K., additional, Boss, E., additional, Brown, R., additional, Chadwick, J., additional, Chalmers, L., additional, Chernausek, S., additional, Hebensperger, A., additional, Macha, C., additional, Newgent, R., additional, Nordyke, A., additional, Olson, D., additional, Poulsen, T., additional, Pratt, L., additional, Preske, J., additional, Schanuel, J., additional, Sternlof, S., additional, Lynch, J., additional, Amodei, N., additional, Barajas, R., additional, Cody, C., additional, Hale, D., additional, Hernandez, J., additional, Ibarra, C., additional, Morales, E., additional, Rivera, S., additional, Rupert, G., additional, Wauters, A., additional, White, N., additional, Arbeláez, A., additional, Jones, J., additional, Jones, T., additional, Sadler, M., additional, Tanner, M., additional, Timpson, A., additional, Welch, R., additional, Caprio, S., additional, Grey, M., additional, Guandalini, C., additional, Lavietes, S., additional, Rose, P., additional, Syme, A., additional, Tamborlane, W., additional, Hirst, K., additional, Edelstein, S., additional, Feit, P., additional, Grover, N., additional, Long, C., additional, Pyle, L., additional, Linder, B., additional, Harting, J., additional, Shepherd, J., additional, Fan, B., additional, Marquez, L., additional, Sherman, M., additional, Wang, J., additional, Nichols, M., additional, Mayer-Davis, E., additional, Liu, Y., additional, Lima, J., additional, Puccella, J., additional, Ricketts, E., additional, Danis, R., additional, Domalpally, A., additional, Goulding, A., additional, Neill, S., additional, Vargo, P., additional, Wilfley, D., additional, Aldrich-Rasche, D., additional, Franklin, K., additional, Massmann, C., additional, O'Brien, D., additional, Patterson, J., additional, Tibbs, T., additional, Van Buren, D., additional, Palmert, M., additional, Ratner, R., additional, Dremaine, D., additional, and Silverstein, J., additional

Published
2018
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42. Insulin Sensitivity and Diabetic Kidney Disease in Children and Adolescents With Type 2 Diabetes: An Observational Analysis of Data From the TODAY Clinical Trial

Author

Bjornstad, Petter, primary, Nehus, Edward, additional, El ghormli, Laure, additional, Bacha, Fida, additional, Libman, Ingrid M., additional, McKay, Siripoom, additional, Willi, Steven M., additional, Laffel, Lori, additional, Arslanian, Silva, additional, Nadeau, Kristen J., additional, McKay, S., additional, Haymond, M., additional, Anderson, B., additional, Bush, C., additional, Gunn, S., additional, Holden, H., additional, Jones, S.M., additional, Jeha, G., additional, McGirk, S., additional, Thamotharan, S., additional, Cuttler, L., additional, Abrams, E., additional, Casey, T., additional, Dahms, W., additional, Ievers-Landis, C., additional, Kaminski, B., additional, Koontz, M., additional, MacLeish, S., additional, McGuigan, P., additional, Narasimhan, S., additional, Geffner, M., additional, Barraza, V., additional, Chang, N., additional, Conrad, B., additional, Dreimane, D., additional, Estrada, S., additional, Fisher, L., additional, Fleury-Milfort, E., additional, Hernandez, S., additional, Hollen, B., additional, Kaufman, F., additional, Law, E., additional, Mansilla, V., additional, Miller, D., additional, Muñoz, C., additional, Ortiz, R., additional, Ward, A., additional, Wexler, K., additional, Xu, Y.K., additional, Yasuda, P., additional, Levitt Katz, L., additional, Berkowitz, R., additional, Boyd, S., additional, Johnson, B., additional, Kaplan, J., additional, Keating, C., additional, Lassiter, C., additional, Lipman, T., additional, McGinley, G., additional, McKnight, H., additional, Schwartzman, B., additional, Willi, S., additional, Arslanian, S., additional, Bacha, F., additional, Foster, S., additional, Galvin, B., additional, Hannon, T., additional, Kriska, A., additional, Libman, I., additional, Marcus, M., additional, Porter, K., additional, Songer, T., additional, Venditti, E., additional, Goland, R., additional, Gallagher, D., additional, Kringas, P., additional, Leibel, N., additional, Ng, D., additional, Ovalles, M., additional, Seidman, D., additional, Laffel, L., additional, Goebel-Fabbri, A., additional, Hall, M., additional, Higgins, L., additional, Keady, J., additional, Malloy, M., additional, Milaszewski, K., additional, Rasbach, L., additional, Nathan, D.M., additional, Angelescu, A., additional, Bissett, L., additional, Ciccarelli, C., additional, Delahanty, L., additional, Goldman, V., additional, Hardy, O., additional, Larkin, M., additional, Levitsky, L., additional, McEachern, R., additional, Norman, D., additional, Nwosu, D., additional, Park-Bennett, S., additional, Richards, D., additional, Sherry, N., additional, Steiner, B., additional, Tollefsen, S., additional, Carnes, S., additional, Dempsher, D., additional, Flomo, D., additional, Whelan, T., additional, Wolff, B., additional, Weinstock, R., additional, Bowerman, D., additional, Bristol, S., additional, Bulger, J., additional, Hartsig, J., additional, Izquierdo, R., additional, Kearns, J., additional, Saletsky, R., additional, Trief, P., additional, Zeitler, P., additional, Abramson, N., additional, Bradhurst, A., additional, Celona-Jacobs, N., additional, Higgins, J., additional, Kelsey, M., additional, Klingensmith, G., additional, Nadeau, K., additional, Witten, T., additional, Copeland, K., additional, Boss, E., additional, Brown, R., additional, Chadwick, J., additional, Chalmers, L., additional, Chernausek, S., additional, Hebensperger, A., additional, Macha, C., additional, Newgent, R., additional, Nordyke, A., additional, Olson, D., additional, Poulsen, T., additional, Pratt, L., additional, Preske, J., additional, Schanuel, J., additional, Sternlof, S., additional, Lynch, J., additional, Amodei, N., additional, Barajas, R., additional, Cody, C., additional, Hale, D., additional, Hernandez, J., additional, Ibarra, C., additional, Morales, E., additional, Rivera, S., additional, Rupert, G., additional, Wauters, A., additional, White, N., additional, Arbeláez, A., additional, Jones, J., additional, Jones, T., additional, Sadler, M., additional, Tanner, M., additional, Timpson, A., additional, Welch, R., additional, Caprio, S., additional, Grey, M., additional, Guandalini, C., additional, Lavietes, S., additional, Rose, P., additional, Syme, A., additional, Tamborlane, W., additional, Hirst, K., additional, Edelstein, S., additional, Feit, P., additional, Grover, N., additional, Long, C., additional, Pyle, L., additional, Linder, B., additional, Marcovina, S.M., additional, Harting, J., additional, Shepherd, J., additional, Fan, B., additional, Marquez, L., additional, Sherman, M., additional, Wang, J., additional, Nichols, M., additional, Mayer-Davis, E., additional, Liu, Y., additional, Lima, J., additional, Gidding, S., additional, Puccella, J., additional, Ricketts, E., additional, Danis, R., additional, Domalpally, A., additional, Goulding, A., additional, Neill, S., additional, Vargo, P., additional, Wilfley, D., additional, Aldrich-Rasche, D., additional, Franklin, K., additional, Massmann, C., additional, O’Brien, D., additional, Patterson, J., additional, Tibbs, T., additional, Van Buren, D., additional, Palmert, M., additional, Ratner, R., additional, Dremaine, D., additional, and Silverstein, J., additional

Published
2018
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43. Nondestructive testing and metrology

Author

Abramson, N., Amelinckx, S., editor, Chebotayev, V. P., editor, Gomer, R., editor, Ibach, H., editor, Letokhov, V. S., editor, Lotsch, Helmut K. V., editor, Queisser, H. J., editor, Schäfer, F. P., editor, Seeger, A., editor, Shimoda, K., editor, Tamir, T., editor, Welford, W. T., editor, Wijn, H. P. J., editor, and Casasent, David, editor

Published
1978
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45. Iodotrimethylsilane-mediated 2-monohalogenation of 4-aza-5a-androstan-3-one steroids

Author

King, Anthony O., Anderson, R. Kevin, Shuman, Richard F., Karady, Sandor, Abramson, N. Lee, and Douglas, Alan W.

Subjects
Fluorination -- Research, Steroids (Drugs) -- Research, Biological sciences, Chemistry
Abstract

A study was made on the selective and high-yielding iodotrimethylsilane(TMSI) mediated 2-monohalogenation of 4-aza-5alpha-androstan-3-one steroids. A mechanism for the reaction was also suggested. The results indicated that a TMSI-mediated halogenation reaction can provide significant yields of different alpha-iodo and alpha-bromo lactams and amides. Other functional groups of choice can also be obtained from the conversion of the products.

Published
1993

46. How good are volunteers at searching for published randomized controlled trials? The OSTR Collaborative Group. Ottawa Stroke Trials Registry

Author

Abramson, N, Adams, H, Algra, A, Asplund, K, Barer, D, Barnett, H, Boissel, J, Britton, M, Brown, M, Buchan, A, Candelise, L, Counsell, C, Cote, R, Castleden, C, Chen, Z, Connolly, S, Czlonkowska, A, Delmaestro, R, Dennis, M, Donnan, G, Downie, M, Duke, R, Ezekowitz, M, Frankel, M, and Fraser, H

Abstract

The Ottawa Stroke Trials Registry (OSTR) collects information on all randomized controlled trials (RCTs), in all languages, in which the primary focus is stroke. Published trials are added to the registry database once they have been identified by volunteers hand searching journals. We undertook this study to assess volunteer sensitivity, specificity, positive and negative predictive values, accuracy and reliability in identifying RCTs. Three volunteers participated in this study. The complete contents of five years of one journal were searched (n = 240) as were ten research reports from five journals. Volunteer sensitivity, specificity, positive and negative predictive values, and accuracy was 89.5%, 100%, 100%, 99.1%, and 99% respectively. Inter volunteer reliability was 0.87. Searching the published literature to identify RCTs is an enormous task. These results indicate that volunteers, with minimal training, can effectively contribute to this endeavour.

Published
2016
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48. Genetic analysis of type material of the Amur lemming resolves nomenclature issues and creates challenges for the taxonomy of true lemmings (Lemmus, Rodentia: Cricetidae) in the eastern Palearctic.

Author

ABRAMSON, N. I. and PETROVA, T. V.

Subjects
*ZOOLOGICAL nomenclature, *TAXONOMY, *PHYLOGENY, *MUSEUMS
Abstract

The proper use of species names depends entirely on verifying whether newly analysed specimens are conspecific with the type material. True lemmings (Lemmus) are the most common rodents of the Arctic tundra in the Old and New World and play an important role in the Arctic ecosystem; however, their taxonomy is far from resolved. The Amur lemming (L. amurensis) is the least studied and most enigmatic species of the genus. Its taxonomic position, distribution and nomenclature are uncertain due to a lack of cytogenetic, molecular phylogenetic and hybridization studies. Assignment of all true lemmings from the vast territory of western Beringia to this species has never properly been confirmed. Moreover, the type locality for this species was flooded by a newly created reservoir in 1974, making additional topotypes unavailable. In this context, genetic analysis of museum specimens, especially type material, has great potential. Here we report partial cytochrome b sequences extracted from all specimens identified as L. amurensis stored in the two largest mammal collections in Russian museums, including the holotype of L. amurensis and the type material of all forms currently considered as synonyms of L. amurensis. Phylogenetic analyses suggest that the range of the Amur lemming is dramatically smaller than previously assumed and is limited to the territories of Transbaikalia, South Yakutia and Amur in the eastern Palaearctic. Lemmus taxa from other territories, including L. amurensis ognevi and L. amurensis flavescens, refer to other lemming species. Our results impinge on nomenclature issues, taxonomy, divergence times and the evolutionary history of lemmings in the eastern part of the Palearctic and on the species concept as applied to the genus Lemmus. [ABSTRACT FROM AUTHOR]

Published
2018
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49. Comparative Assessment of Genetic Structure in Invasive and Autochthonous Populations of Harmonia axyridis(Pallas) (Coleoptera, Coccinellidae)

Author

Bondareva, O. V., Abramson, N. I., Ovchinnikov, A. N., and Belyakova, N. A.

Abstract

The genetic diversity of two native Siberian and two invasive European populations of the Asian ladybird Harmonia axyridiswas studied under laboratory conditions. Analysis of the population genetic structure revealed a high degree of isolation of the monomorphic population from Sochi, monomorphism of the population from Serbia, and high genetic heterogeneity of the populations from Novosibirsk and Altai. The allelic profile data showed that the Novosibirsk population contained the greatest number of alleles. Our preliminary results indicate high genetic homogeneity of the Sochi population, which is consistent with the initial stage of expansion and contradicts the hypothesis of its hybrid origin.

Published
2019
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50. Voluntary Screening Program for Prostate Cancer: Detection Rate and Cost

Author

Abramson N, Baldock J, Cotton S, and Eckels R

Subjects
Male, Oncology, medicine.medical_specialty, Cost estimate, Biopsy, Treatment outcome, Prostate cancer, Internal medicine, medicine, Humans, Mass Screening, Initial therapy, Physical Examination, health care economics and organizations, Aged, medicine.diagnostic_test, business.industry, Carcinoma, Prostatic Neoplasms, Reproducibility of Results, Cancer, Health Care Costs, General Medicine, Rectal examination, Middle Aged, Prostate-Specific Antigen, medicine.disease, Emergency medicine, Costs and Cost Analysis, Florida, Antigen measurement, Detection rate, business
Abstract

In a community-wide screening program conducted in Jacksonville, Florida, 564 participants received free screening for prostate cancer. Frequency of positive results of prostate-specific antigen measurement and digital rectal examination was comparable to that found in similar programs in other communities. The estimated cost for each participant was $231, and the cost to discover each cancer was $7,240. If one also includes initial therapy in cost estimates, then the cost per participant was $520, and the cost to find and treat each patient was $16,300. The value of screening for prostate cancer must be judged by treatment outcome and underlying costs.

Published
1994
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