Search

Purpose: To describe clinical manifestations, diagnostic approaches, therapy, and outcomes of biopsy-proven intraocular lymphoma.Methods: Review of tertiary referral center records between 2005 and 2015.Results: A total of 51 eyes of 26 patients were included; mean age of onset was 60.42 years. Common ocular complaints included floaters (42%) and blurred vision (35%); 62% of patients had ocular and central nervous system involvement; 11% had systemic lymphoma; and 27% had only ocular involvement. Vitreous analysis was positive for malignant cells in 77% of patients on initial biopsy, and in 100% of patients on repeat biopsy. In total, 20/26 patients received systemic and topical treatment before IOL diagnosis was made; 25 patients received intravitreal methotrexate and/or rituximab; one patient received intracameral rituximab. All patients achieved remission by their final visit.Conclusions: Intraocular lymphoma often masquerades as intraocular inflammation, resulting in delayed or misdiagnosis with subsequent inappropriate management. Optimal therapy is a challenge for oncologists and ophthalmologists. [ABSTRACT FROM AUTHOR]

Purpose: To identify the risk factors associated with diabetic retinopathy among diabetic patients at Jordan University Hospital., Methods: A total of 986 patients with diabetes mellitus were assessed at Jordan University Hospital. The assessment included detailed relevant history, complete medical and ophthalmic evaluation., Results: Out of the 1961 eye examined, 64.1 percent had one form of diabetic retinopathy; 54.8 percent had nonproliferative diabetic retinopathy (NPDR), 9.3 percent had proliferative diabetic retinopathy (PDR) and 30.8 percent had maculopathy. Of all participants, 23.5 percent had combined NPDR and maculopathy while 7.6 percent had PDR and maculopathy. Using logistic regression analysis it was shown that old age group, long duration of diabetes, poor glycemic control, uncontrolled blood pressure and the presence of nephropathy were significantly associated with diabetic retinopathy. The incidence of maculopathy was significantly associated with the presence of hypertension, protienuria and high cholesterol level., Conclusion: The challenge for the primary care physician and diabetologist is to attain excellent glycemic control, aggressive control of blood pressure and normalization of blood lipid in order to reduce the risk of blindness and lessen the burden from diabetic retinopathy.