1. Feasibility and Clinical Acceptability of Automation-Assisted 3D Conformal Radiotherapy Planning for Patients With Cervical Cancer in a Resource-Constrained Setting.
- Author
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Muya, Sikudhani, Ndumbalo, Jerry, Kutika Nyagabona, Sarah, Yusuf, Shaid, Rhee, Dong, Mushi, Beatrice, Li, Benjamin, Grover, Surbhi, Feng, Mary, Mmbaga, Elia, Van Loon, Katherine, Court, Laurence, Xu, Melody, Hsu, I-Chow, and Zhang, Li
- Subjects
Humans ,Female ,Uterine Cervical Neoplasms ,Feasibility Studies ,Radiotherapy ,Conformal ,Academies and Institutes ,Automation - Abstract
PURPOSE: The Ocean Road Cancer Institute (ORCI) in Tanzania began offering 3D conformal radiation therapy (3DCRT) in 2018. Steep learning curves, high patient volume, and a limited workforce resulted in long radiation therapy (RT) planning workflows. We aimed to establish the feasibility of implementing an automation-assisted cervical cancer 3DCRT planning system. MATERIALS AND METHODS: We performed chart abstractions on 30 patients with cervical cancer treated with 3DCRT at ORCI. The Radiation Planning Assistant (RPA) generated a new automated set of contours and plans on the basis of anonymized computed tomography images. Each were assessed for edit time requirements, dose-volume safety metrics, and clinical acceptability by two ORCI physician investigators. Dice similarity coefficient (DSC) agreement analysis was conducted between original and new contour sets. RESULTS: The average time to manually develop treatment plans was 7 days. Applying RPA, automated same-day contours and plans were developed for 29 of 30 patients (97%). Of the 29 evaluable contours, all were approved with
- Published
- 2023