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2. Quality indicators for colonoscopy

Author

Rex, Douglas K., Anderson, Joseph C., Butterly, Lynn F., Day, Lukejohn W., Dominitz, Jason A., Kaltenbach, Tonya, Ladabaum, Uri, Levin, Theodore R., Shaukat, Aasma, Achkar, Jean-Paul, Farraye, Francis A., Kane, Sunanda V., and Shaheen, Nicholas J.

Published
2024
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5. HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44+ Natural Killer Cells in Ulcerative Colitis

Author

Akar, Alaa, Flemming, Cornelius, Felix, Flomm, Flosbach, Markus, Jäger, Julia, Jeromin, Niklas, Jung, Johannes, Ohms, Mareike, Reinshagen, Konrad, Rische, Johann, Sagebiel, Adrian, Sandfort, Deborah, Steinert, Fenja, Tomuschat, Christian, Wesche, Jasmin, Shifteh Abedian, Abraham, Clara, Achkar, Jean-Paul, Ahmad, Tariq, Alberts, Rudi, Alizadeh, Behrooz, Amininejad, Leila, Ananthakrishnan, Ashwin N., Andersen, Vibeke, Anderson, Carl A., Andrews, Jane M., Annese, Vito, Aumais, Guy, Baidoo, Leonard, Baldassano, Robert N., Bampton, Peter A., Barclay, Murray, Barrett, Jeffrey C., Bethge, Johannes, Bewshea, Claire, Bis, Joshua C., Bitton, Alain, BK, Thelma, Boucher, Gabrielle, Brain, Oliver, Brand, Stephan, Brant, Steven R., Cheon, Jae Hee, Chew, Angela, Cho, Judy H., Cleynen, Isabelle, Cohain, Ariella, Cooney, Rachel, Croft, Anthony, Daly, Mark J., D'Amato, Mauro, Danese, Silvio, Daryani, Naser Ebrahim, Datta, Lisa Wu, Degenhardt, Frauke, Denapiene, Goda, Denson, Lee A., Devaney, Kathy L., Dewit, Olivier, D'Inca, Renata, Drummond, Hazel E., Dubinsky, Marla, Duerr, Richard H., Edwards, Cathryn, Ellinghaus, David, Ellul, Pierre, Esaki, Motohiro, Essers, Jonah, Ferguson, Lynnette R., Festen, Eleonora A., Fleshner, Philip, Florin, Tim, Franchimont, Denis, Franke, Andre, Fuyuno, Yuta, Gearry, Richard, Georges, Michel, Gieger, Christian, Glas, Jürgen, Goyette, Philippe, Green, Todd, Griffiths, Anne M., Guthery, Stephen L., Hakonarson, Hakon, Halfvarson, Jonas, Hanigan, Katherine, Haritunians, Talin, Hart, Ailsa, Hawkey, Chris, Hayward, Nicholas K., Hedl, Matija, Henderson, Paul, Hold, Georgina L., Hong, Myhunghee, Hu, Xinli, Huang, Hailiang, Hugot, Jean-Pierre, Hui, Ken Y., Imielinski, Marcin, Jazayeri, Omid, Jonaitis, Laimas, Jostins, Luke, Juyal, Garima, Chandra Juyal, Ramesh, Kalla, Rahul, Karlsen, Tom H., Kennedy, Nicholas A., Khan, Mohammed Azam, Kim, Won Ho, Kitazono, Takanari, Kiudelis, Gediminas, Kubo, Michiaki, Kugathasan, Subra, Kupcinskas, Limas, Lamb, Christopher A., de Lange, Katrina M., Latiano, Anna, Laukens, Debby, Lawrance, Ian C., Lee, James C., Lees, Charlie W., Leja, Marcis, Lewis, Nina, Van Limbergen, Johan, Lionetti, Paolo, Liu, Jimmy Z., Louis, Edouard, Luo, Yang, Mahy, Gillian, Malekzadeh, Masoud Mohammad, Malekzadeh, Reza, Mansfield, John, Marriott, Suzie, Massey, Dunecan, Mathew, Christopher G., Matsui, Toshiyuki, McGovern, Dermot P.B., van der Meulen, Andrea, Midha, Vandana, Milgrom, Raquel, Mirzaei, Samaneh, Mitrovic, Mitja, Montgomery, Grant W., Mowat, Craig, Müller, Christoph, Newman, William G., Ng, Aylwin, Ng, Siew C., Evelyn Ng, Sok Meng, Nikolaus, Susanna, Ning, Kaida, Nöthen, Markus, Oikonomou, Ioannis, Okou, David, Orchard, Timothy R., Palmieri, Orazio, Parkes, Miles, Phillips, Anne, Ponsioen, Cyriel Y., Potocnik, Urõs, Poustchi, Hossein, Prescott, Natalie J., Proctor, Deborah D., Radford-Smith, Graham, Rahier, Jean- Francois, Regueiro, Miguel, Reinisch, Walter, Rieder, Florian, Rioux, John D., Roberts, Rebecca, Rogler, Gerhard, Russell, Richard K., Sanderson, Jeremy D., Sans, Miquel, Satsangi, Jack, Schadt, Eric E., Scharl, Michael, Schembri, John, Schreiber, Stefan, Schumm, L. Philip, Scott, Regan, Seielstad, Mark, Shah, Tejas, Sharma, Yashoda, Silverberg, Mark S., Simmons, Alison, Simms, Lisa A., Singh, Abhey, Skieceviciene, Jurgita, van Sommeren, Suzanne, Song, Kyuyoung, Sood, Ajit, Spain, Sarah L., Steinhart, A. Hillary, Stempak, Joanne M., Stronati, Laura, Sung, Joseph J.Y., Targan, Stephan R., Taylor, Kirstin M., Theatre, Emilie, Torkvist, Leif, Torres, Esther A., Tremelling, Mark, Uhlig, Holm H., Umeno, Junji, Vahedi, Homayon, Vasiliauskas, Eric, Velde, Anje ter, Ventham, Nicholas T., Vermeire, Severine, Verspaget, Hein W., De Vos, Martine, Walters, Thomas, Wang, Kai, Wang, Ming-Hsi, Weersma, Rinse K., Wei, Zhi, Whiteman, David, Wijmenga, Cisca, Wilson, David C., Winkelmann, Juliane, Wong, Sunny H., Xavier, Ramnik J., Yamazaki, Keiko, Yang, Suk-Kyun, Ye, Byong Duk, Zeissig, Sebastian, Zhang, Bin, Zhang, Clarence K., Zhang, Hu, Zhang, Wei, Zhao, Hongyu, Zhao, Zhen Z., Baumdick, Martin E., Niehrs, Annika, Schwerk, Maria, Hinrichs, Ole, Jordan-Paiz, Ana, Padoan, Benedetta, Wegner, Lucy H.M., Schloer, Sebastian, Zecher, Britta F., Malsy, Jakob, Joshi, Vinita R., Illig, Christin, Schröder-Schwarz, Jennifer, Möller, Kimberly J., Martin, Maureen P., Yuki, Yuko, Ozawa, Mikki, Sauter, Jürgen, Schmidt, Alexander H., Perez, Daniel, Giannou, Anastasios D., Carrington, Mary, Davis, Randall S., Schumacher, Udo, Sauter, Guido, Huber, Samuel, Puelles, Victor G., Melling, Nathaniel, Altfeld, Marcus, and Bunders, Madeleine J.

Published
2023
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7. Test Characteristics of Cross-sectional Imaging and Concordance With Endoscopy in Postoperative Crohn’s Disease

Author

Bachour, Salam P., Shah, Ravi S., Lyu, Ruishen, Nakamura, Takahiro, Shen, Michael, Li, Terry, Dane, Bari, Barnes, Edward L., Rieder, Florian, Cohen, Benjamin, Qazi, Taha, Lashner, Bret, Achkar, Jean Paul, Philpott, Jessica, Holubar, Stefan D., Lightner, Amy L., Regueiro, Miguel, Axelrad, Jordan, Baker, Mark E., and Click, Benjamin

Published
2022
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11. Postoperative Crohn’s Disease Recurrence Risk and Optimal Biologic Timing After Temporary Diversion Following Ileocolic Resection

Author

Joseph, Abel, primary, Bachour, Salam P, additional, Shah, Ravi, additional, El Halabi, Jessica, additional, Syed, Hareem, additional, Lyu, Ruishen, additional, Cohen, Benjamin, additional, Rieder, Florian, additional, Achkar, Jean-Paul, additional, Philpott, Jessica, additional, Qazi, Taha, additional, Hull, Tracy, additional, Lipman, Jeremy, additional, Wexner, Steven, additional, Holubar, Stefan D, additional, Regueiro, Miguel, additional, and Click, Benjamin, additional

Published
2024
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12. A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn’s Disease and Human Gut Microbiome Composition

Author

Li, Dalin, Achkar, Jean-Paul, Haritunians, Talin, Jacobs, Jonathan P, Hui, Ken Y, D'Amato, Mauro, Brand, Stephan, Radford-Smith, Graham, Halfvarson, Jonas, Niess, Jan-Hendrik, Kugathasan, Subra, Büning, Carsten, Schumm, L Philip, Klei, Lambertus, Ananthakrishnan, Ashwin, Aumais, Guy, Baidoo, Leonard, Dubinsky, Marla, Fiocchi, Claudio, Glas, Jürgen, Milgrom, Raquel, Proctor, Deborah D, Regueiro, Miguel, Simms, Lisa A, Stempak, Joanne M, Targan, Stephan R, Törkvist, Leif, Sharma, Yashoda, Devlin, Bernie, Borneman, James, Hakonarson, Hakon, Xavier, Ramnik J, Daly, Mark, Brant, Steven R, Rioux, John D, Silverberg, Mark S, Cho, Judy H, Braun, Jonathan, McGovern, Dermot PB, and Duerr, Richard H

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Nutrition and Dietetics, Microbiome, Crohn's Disease, Women's Health, Clinical Research, Human Genome, Autoimmune Disease, Inflammatory Bowel Disease, Digestive Diseases, Nutrition, Genetics, 2.1 Biological and endogenous factors, Oral and gastrointestinal, Alleles, Case-Control Studies, Cation Transport Proteins, Colitis, Ulcerative, Crohn Disease, Female, Gastrointestinal Microbiome, Genetic Pleiotropy, Genotype, Humans, Male, Mutation, Missense, Risk Factors, Inflammatory Bowel Diseases, Microbiota, Neurosciences, Paediatrics and Reproductive Medicine, Gastroenterology & Hepatology, Clinical sciences, Nutrition and dietetics
Abstract

Background & aimsGenome-wide association studies have identified 200 inflammatory bowel disease (IBD) loci, but the genetic architecture of Crohn's disease (CD) and ulcerative colitis remain incompletely defined. Here, we aimed to identify novel associations between IBD and functional genetic variants using the Illumina ExomeChip (San Diego, CA).MethodsGenotyping was performed in 10,523 IBD cases and 5726 non-IBD controls. There were 91,713 functional single-nucleotide polymorphism loci in coding regions analyzed. A novel identified association was replicated further in 2 independent cohorts. We further examined the association of the identified single-nucleotide polymorphism with microbiota from 338 mucosal lavage samples in the Mucosal Luminal Interface cohort measured using 16S sequencing.ResultsWe identified an association between CD and a missense variant encoding alanine or threonine at position 391 in the zinc transporter solute carrier family 39, member 8 protein (SLC39A8 alanine 391 threonine, rs13107325) and replicated the association with CD in 2 replication cohorts (combined meta-analysis P = 5.55 × 10(-13)). This variant has been associated previously with distinct phenotypes including obesity, lipid levels, blood pressure, and schizophrenia. We subsequently determined that the CD risk allele was associated with altered colonic mucosal microbiome composition in both healthy controls (P = .009) and CD cases (P = .0009). Moreover, microbes depleted in healthy carriers strongly overlap with those reduced in CD patients (P = 9.24 × 10(-16)) and overweight individuals (P = 6.73 × 10(-16)).ConclusionsOur results suggest that an SLC39A8-dependent shift in the gut microbiome could explain its pleiotropic effects on multiple complex diseases including CD.

Published
2016

17. Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

Author

Liu, Jimmy Z, Hov, Johannes Roksund, Folseraas, Trine, Ellinghaus, Eva, Rushbrook, Simon M, Doncheva, Nadezhda T, Andreassen, Ole A, Weersma, Rinse K, Weismüller, Tobias J, Eksteen, Bertus, Invernizzi, Pietro, Hirschfield, Gideon M, Gotthardt, Daniel Nils, Pares, Albert, Ellinghaus, David, Shah, Tejas, Juran, Brian D, Milkiewicz, Piotr, Rust, Christian, Schramm, Christoph, Müller, Tobias, Srivastava, Brijesh, Dalekos, Georgios, Nöthen, Markus M, Herms, Stefan, Winkelmann, Juliane, Mitrovic, Mitja, Braun, Felix, Ponsioen, Cyriel Y, Croucher, Peter JP, Sterneck, Martina, Teufel, Andreas, Mason, Andrew L, Saarela, Janna, Leppa, Virpi, Dorfman, Ruslan, Alvaro, Domenico, Floreani, Annarosa, Onengut-Gumuscu, Suna, Rich, Stephen S, Thompson, Wesley K, Schork, Andrew J, Næss, Sigrid, Thomsen, Ingo, Mayr, Gabriele, König, Inke R, Hveem, Kristian, Cleynen, Isabelle, Gutierrez-Achury, Javier, Ricaño-Ponce, Isis, van Heel, David, Björnsson, Einar, Sandford, Richard N, Durie, Peter R, Melum, Espen, Vatn, Morten H, Silverberg, Mark S, Duerr, Richard H, Padyukov, Leonid, Brand, Stephan, Sans, Miquel, Annese, Vito, Achkar, Jean-Paul, Boberg, Kirsten Muri, Marschall, Hanns-Ulrich, Chazouillères, Olivier, Bowlus, Christopher L, Wijmenga, Cisca, Schrumpf, Erik, Vermeire, Severine, Albrecht, Mario, UK-PSCSC Consortium, Rioux, John D, Alexander, Graeme, Bergquist, Annika, Cho, Judy, Schreiber, Stefan, Manns, Michael P, Färkkilä, Martti, Dale, Anders M, Chapman, Roger W, Lazaridis, Konstantinos N, International PSC Study Group, Franke, Andre, Anderson, Carl A, Karlsen, Tom H, and International IBD Genetics Consortium

Subjects
UK-PSCSC Consortium, International PSC Study Group, International IBD Genetics Consortium, Humans, Cholangitis, Sclerosing, Oligonucleotide Array Sequence Analysis, Risk Factors, Case-Control Studies, Gene Frequency, Linkage Disequilibrium, Polymorphism, Single Nucleotide, Genome-Wide Association Study, Genetic Loci, Genetic Pleiotropy, Genotyping Techniques, Developmental Biology, Biological Sciences, Medical and Health Sciences
Abstract

Primary sclerosing cholangitis (PSC) is a severe liver disease of unknown etiology leading to fibrotic destruction of the bile ducts and ultimately to the need for liver transplantation. We compared 3,789 PSC cases of European ancestry to 25,079 population controls across 130,422 SNPs genotyped using the Immunochip. We identified 12 genome-wide significant associations outside the human leukocyte antigen (HLA) complex, 9 of which were new, increasing the number of known PSC risk loci to 16. Despite comorbidity with inflammatory bowel disease (IBD) in 72% of the cases, 6 of the 12 loci showed significantly stronger association with PSC than with IBD, suggesting overlapping yet distinct genetic architectures for these two diseases. We incorporated association statistics from 7 diseases clinically occurring with PSC in the analysis and found suggestive evidence for 33 additional pleiotropic PSC risk loci. Together with network analyses, these findings add to the genetic risk map of PSC and expand on the relationship between PSC and other immune-mediated diseases.

Published
2013

18. Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Author

Jostins, Luke, Ripke, Stephan, Weersma, Rinse K, Duerr, Richard H, McGovern, Dermot P, Hui, Ken Y, Lee, James C, Philip Schumm, L, Sharma, Yashoda, Anderson, Carl A, Essers, Jonah, Mitrovic, Mitja, Ning, Kaida, Cleynen, Isabelle, Theatre, Emilie, Spain, Sarah L, Raychaudhuri, Soumya, Goyette, Philippe, Wei, Zhi, Abraham, Clara, Achkar, Jean-Paul, Ahmad, Tariq, Amininejad, Leila, Ananthakrishnan, Ashwin N, Andersen, Vibeke, Andrews, Jane M, Baidoo, Leonard, Balschun, Tobias, Bampton, Peter A, Bitton, Alain, Boucher, Gabrielle, Brand, Stephan, Büning, Carsten, Cohain, Ariella, Cichon, Sven, D’Amato, Mauro, De Jong, Dirk, Devaney, Kathy L, Dubinsky, Marla, Edwards, Cathryn, Ellinghaus, David, Ferguson, Lynnette R, Franchimont, Denis, Fransen, Karin, Gearry, Richard, Georges, Michel, Gieger, Christian, Glas, Jürgen, Haritunians, Talin, Hart, Ailsa, Hawkey, Chris, Hedl, Matija, Hu, Xinli, Karlsen, Tom H, Kupcinskas, Limas, Kugathasan, Subra, Latiano, Anna, Laukens, Debby, Lawrance, Ian C, Lees, Charlie W, Louis, Edouard, Mahy, Gillian, Mansfield, John, Morgan, Angharad R, Mowat, Craig, Newman, William, Palmieri, Orazio, Ponsioen, Cyriel Y, Potocnik, Uros, Prescott, Natalie J, Regueiro, Miguel, Rotter, Jerome I, Russell, Richard K, Sanderson, Jeremy D, Sans, Miquel, Satsangi, Jack, Schreiber, Stefan, Simms, Lisa A, Sventoraityte, Jurgita, Targan, Stephan R, Taylor, Kent D, Tremelling, Mark, Verspaget, Hein W, De Vos, Martine, Wijmenga, Cisca, Wilson, David C, Winkelmann, Juliane, Xavier, Ramnik J, Zeissig, Sebastian, Zhang, Bin, Zhang, Clarence K, Zhao, Hongyu, Silverberg, Mark S, Annese, Vito, Hakonarson, Hakon, Brant, Steven R, Radford-Smith, Graham, Mathew, Christopher G, Rioux, John D, and Schadt, Eric E

Subjects
Epidemiology, Biological Sciences, Health Sciences, Genetics, Crohn's Disease, Human Genome, Autoimmune Disease, Inflammatory Bowel Disease, Digestive Diseases, 2.1 Biological and endogenous factors, Oral and gastrointestinal, Colitis, Ulcerative, Crohn Disease, Genetic Predisposition to Disease, Genome, Human, Genome-Wide Association Study, Haplotypes, Host-Pathogen Interactions, Humans, Inflammatory Bowel Diseases, Mycobacterium, Mycobacterium Infections, Mycobacterium tuberculosis, Phenotype, Polymorphism, Single Nucleotide, Reproducibility of Results, International IBD Genetics Consortium, General Science & Technology
Abstract

Crohn's disease and ulcerative colitis, the two common forms of inflammatory bowel disease (IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other populations. Genome-wide association studies and subsequent meta-analyses of these two diseases as separate phenotypes have implicated previously unsuspected mechanisms, such as autophagy, in their pathogenesis and showed that some IBD loci are shared with other inflammatory diseases. Here we expand on the knowledge of relevant pathways by undertaking a meta-analysis of Crohn's disease and ulcerative colitis genome-wide association scans, followed by extensive validation of significant findings, with a combined total of more than 75,000 cases and controls. We identify 71 new associations, for a total of 163 IBD loci, that meet genome-wide significance thresholds. Most loci contribute to both phenotypes, and both directional (consistently favouring one allele over the course of human history) and balancing (favouring the retention of both alleles within populations) selection effects are evident. Many IBD loci are also implicated in other immune-mediated disorders, most notably with ankylosing spondylitis and psoriasis. We also observe considerable overlap between susceptibility loci for IBD and mycobacterial infection. Gene co-expression network analysis emphasizes this relationship, with pathways shared between host responses to mycobacteria and those predisposing to IBD.

Published
2012

21. Ulcerative colitis–risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

Author

Silverberg, Mark S, Cho, Judy H, Rioux, John D, McGovern, Dermot PB, Wu, Jing, Annese, Vito, Achkar, Jean-Paul, Goyette, Philippe, Scott, Regan, Xu, Wei, Barmada, M Michael, Klei, Lambertus, Daly, Mark J, Abraham, Clara, Bayless, Theodore M, Bossa, Fabrizio, Griffiths, Anne M, Ippoliti, Andrew F, Lahaie, Raymond G, Latiano, Anna, Paré, Pierre, Proctor, Deborah D, Regueiro, Miguel D, Steinhart, A Hillary, Targan, Stephan R, Schumm, L Philip, Kistner, Emily O, Lee, Annette T, Gregersen, Peter K, Rotter, Jerome I, Brant, Steven R, Taylor, Kent D, Roeder, Kathryn, and Duerr, Richard H

Subjects
Biological Sciences, Genetics, Digestive Diseases, Prevention, Human Genome, Inflammatory Bowel Disease, Nutrition, Autoimmune Disease, 2.1 Biological and endogenous factors, Butyrophilins, Case-Control Studies, Chromosomes, Human, Pair 1, Chromosomes, Human, Pair 12, Chromosomes, Human, Pair 6, Colitis, Ulcerative, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Genotype, HLA-DQ Antigens, HLA-DQ beta-Chains, Humans, Male, Membrane Glycoproteins, Polymorphism, Single Nucleotide, Receptors, Interleukin, Recombination, Genetic, Risk Factors, Medical and Health Sciences, Developmental Biology, Agricultural biotechnology, Bioinformatics and computational biology
Abstract

Ulcerative colitis is a chronic inflammatory disease of the colon that presents as diarrhea and gastrointestinal bleeding. We performed a genome-wide association study using DNA samples from 1,052 individuals with ulcerative colitis and preexisting data from 2,571 controls, all of European ancestry. In an analysis that controlled for gender and population structure, ulcerative colitis loci attaining genome-wide significance and subsequent replication in two independent populations were identified on chromosomes 1p36 (rs6426833, combined P = 5.1 x 10(-13), combined odds ratio OR = 0.73) and 12q15 (rs1558744, combined P = 2.5 x 10(-12), combined OR = 1.35). In addition, combined genome-wide significant evidence for association was found in a region spanning BTNL2 to HLA-DQB1 on chromosome 6p21 (rs2395185, combined P = 1.0 x 10(-16), combined OR = 0.66) and at the IL23R locus on chromosome 1p31 (rs11209026, combined P = 1.3 x 10(-8), combined OR = 0.56; rs10889677, combined P = 1.3 x 10(-8), combined OR = 1.29).

Published
2009

24. Gastrointestinal Amyloid Screening Study (GASS): is screening for amyloid in the gastrointestinal tract useful?

Author

Khedraki, Rola, El-Roumi, Joseph, Allende, Daniela, Ives, Lauren, Garber, Ari, RubioTapia, Alberto, Achkar, Jean Paul, Cline, Michael, Baggott, Brian, Cohen, Benjamin, Rieder, Florian, and Hanna, Mazen

Subjects
BARRETT'S esophagus, CARPAL tunnel syndrome, SHORT bowel syndrome, IRRITABLE colon, CONGO red (Staining dye), GASTROPARESIS, CARDIAC amyloidosis
Abstract

The article discusses the Gastrointestinal Amyloid Screening Study (GASS), which aimed to determine the usefulness of screening for amyloid in the gastrointestinal (GI) tract. Amyloidosis is a condition characterized by the accumulation of insoluble amyloid fibrils in various organs. The study enrolled patients over the age of 35 who were undergoing endoscopy for GI symptoms associated with amyloidosis. However, after staining biopsy samples with Congo red, no amyloid deposits were found in the GI samples. The study suggests that routine testing for GI amyloid deposition in patients with characteristic GI symptoms may not be useful. [Extracted from the article]

Published
2024
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30. List of Contributors

Author

Abraham, Jay P., primary, Achkar, Jean-Paul, additional, Ali, Saeed, additional, Ashburn, Jean H., additional, Bruining, David H., additional, Chang, Michael D., additional, Chang, Shannon, additional, Chen, Min, additional, Deepak, Parakkal, additional, Honor, Ann, additional, Kaltenbach, Tonya, additional, Kheir, Ammar O., additional, Ko, Jeffrey Z., additional, Kronberg, Udo, additional, Li, Yi, additional, Lightner, Amy L., additional, Liu, Xiuli, additional, Maric, Leyla, additional, Navaneethan, Udayakumar, additional, Oberc, Abigail, additional, Parikh, Malav P., additional, Sanaka, Madhusudhan R., additional, Schneider, Alison, additional, Schwartz, David A., additional, Sheedy, Shannon P., additional, Shen, Bo, additional, Shih, David Q., additional, Soetikno, Roy, additional, Wainstein, Claudio, additional, Wu, Xian-rui, additional, and Zhu, Weiming, additional

Published
2018
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32. Inhibition of pyrimidine synthesis in murine skin wounds induces a pyoderma gangrenosum-like neutrophilic dermatosis accompanied by spontaneous gut inflammation

Author

Jatana, Samreen, primary, Ponti, András K., additional, Johnson, Erin E., additional, Rebert, Nancy A., additional, Smith, Jordyn L., additional, Fulmer, Clifton G., additional, Maytin, Edward V., additional, Achkar, Jean-Paul, additional, Fernandez, Anthony P., additional, and McDonald, Christine, additional

Published
2022
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33. S122 Three-Dimensional Morphologic Analysis of Severe, Occult Ileoanal Pouch Pathology Using Manual Staple-Line Segmentation: A Proof-of-Concept Study

Author

Nachand, Doug, primary, Prien, Christopher, additional, Lincango, Eddy, additional, Achkar, Jean Paul, additional, Baker, Mark, additional, Carnell, Casey, additional, Cohen, Benjamin, additional, Philpott, Jessica, additional, Lipman, Jeremy, additional, Hull, Tracy, additional, Ream, Justin, additional, McHugh, Jacqueline, additional, Lashner, Bret, additional, Falloon, Katherine, additional, Qazi, Taha, additional, Gorgun, Emre, additional, Rieder, Florian, additional, Regueiro, Miguel, additional, Steele, Scott, additional, and Holubar, Stefan, additional

Published
2022
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37. Reply

Author

Kerbage, Anthony, Achkar, Jean-Paul, and Rouphael, Carol

Published
2024
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38. Intra-abdominal septic complications after ileocolic resection increases risk for endoscopic and surgical postoperative Crohn’s disease recurrence

Author

Bachour, Salam P, primary, Shah, Ravi S, additional, Rieder, Florian, additional, Qazi, Taha, additional, Achkar, Jean Paul, additional, Philpott, Jessica, additional, Lashner, Bret, additional, Holubar, Stefan D, additional, Lightner, Amy L, additional, Barnes, Edward L, additional, Axelrad, Jordan, additional, Regueiro, Miguel, additional, Click, Benjamin, additional, and Cohen, Benjamin L, additional

Published
2022
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40. 719: POSTOPERATIVE CROHN'S DISEASE RECURRENCE RISK AND OPTIMAL BIOLOGIC TIMING AFTER TEMPORARY DIVERSION FOLLOWING ILEOCECAL RESECTION

Author

Joseph, Abel, primary, Bachour, Salam P., additional, Shah, Ravi S., additional, Halabi, Jessica El, additional, Cohen, Benjamin L., additional, Rieder, Florian, additional, Achkar, Jean-Paul, additional, Philpott, Jessica, additional, Qazi, Taha, additional, Lightner, Amy L., additional, Hull, Tracy L., additional, Lipman, Jeremy M., additional, Holubar, Stefan D., additional, Regueiro, Miguel D., additional, and Click, Benjamin, additional

Published
2022
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41. Sa1591: INTRAABDOMINAL SEPTIC COMPLICATIONS AFTER ILEOCOLIC RESECTION INCREASES ENDOSCOPIC POSTOPERATIVE CROHN'S DISEASE RECURRENCE

Author

Bachour, Salam P., primary, Shah, Ravi S., additional, Rieder, Florian, additional, Qazi, Taha, additional, Achkar, Jean-Paul, additional, Philpott, Jessica, additional, Holubar, Stefan D., additional, Lightner, Amy L., additional, Barnes, Edward L., additional, Axelrad, Jordan E., additional, Regueiro, Miguel D., additional, Click, Benjamin, additional, and Cohen, Benjamin L., additional

Published
2022
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42. Mo1555: PRE-OPERATIVE USE OF MULTIPLE BIOLOGIC AND SMALL MOLECULE DRUGS IS NOT ASSOCIATED WITH SUBSEQUENT ENDOSCOPIC INFLAMMATORY POUCH DISEASES

Author

Powers, Joseph C., primary, Cohen, Benjamin L., additional, Rieder, Florian, additional, Lyu, Ruishen, additional, Lashner, Bret, additional, Click, Benjamin, additional, Achkar, Jean-Paul, additional, Philpott, Jessica, additional, Holubar, Stefan D., additional, Agarwal, Mitali, additional, Regueiro, Miguel D., additional, and Qazi, Taha, additional

Published
2022
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43. 456: CHRONOLOGIC AGE IS NOT ASSOCIATED WITH RISK OF POSTOPERATIVE RECURRENCE IN CROHN'S DISEASE

Author

Halabi, Jessica El, primary, Bachour, Salam P., additional, Shah, Ravi S., additional, Joseph, Abel, additional, Cohen, Benjamin L., additional, Rieder, Florian, additional, Achkar, Jean-Paul, additional, Philpott, Jessica, additional, Qazi, Taha, additional, Lightner, Amy L., additional, Hull, Tracy L., additional, Lipman, Jeremy M., additional, Holubar, Stefan D., additional, Regueiro, Miguel D., additional, and Click, Benjamin, additional

Published
2022
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44. 401: ANASTOMOTIC CONFIGURATION AND DIVERTING OSTOMY DOES NOT INCREASE THE RISK OF POSTOPERATIVE ANASTOMOTIC STRICTURES IN CROHN'S DISEASE

Author

Khan, Muhammad Zarrar, primary, Bachour, Salam P., additional, Shah, Ravi S., additional, Cohen, Benjamin L., additional, Rieder, Florian, additional, Achkar, Jean-Paul, additional, Philpott, Jessica, additional, Qazi, Taha, additional, Lightner, Amy L., additional, Hull, Tracy L., additional, Lipman, Jeremy M., additional, Holubar, Stefan D., additional, Barnes, Edward L., additional, Axelrad, Jordan E., additional, Regueiro, Miguel D., additional, and Click, Benjamin, additional

Published
2022
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45. sj-docx-1-mdm-10.1177_0272989X221103508 – Supplemental material for Computable Phenotype of a Crohn’s Disease Natural History Model

Author

Kurowski, Jacob A., Achkar, Jean-Paul, Sugano, David, Milinovich, Alex, Ji, Xinge, Bauman, Janine, Griffin, Keyonna R., and Kattan, Michael W.

Subjects
111708 Health and Community Services, 111799 Public Health and Health Services not elsewhere classified, 160807 Sociological Methodology and Research Methods, FOS: Health sciences, FOS: Sociology
Abstract

Supplemental material, sj-docx-1-mdm-10.1177_0272989X221103508 for Computable Phenotype of a Crohn’s Disease Natural History Model by Jacob A. Kurowski, Jean-Paul Achkar, David Sugano, Alex Milinovich, Xinge Ji, Janine Bauman, Keyonna R. Griffin and Michael W. Kattan in Medical Decision Making

Published
2022
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46. List of Contributors

Author

Achkar, Jean-Paul, primary, Amaral, Flavio A., additional, Arnò, Caterina, additional, Boraschi, Diana, additional, Calderaro, Debora C., additional, Comi, Giancarlo, additional, Crombet, Tania, additional, Duschl, Albert, additional, Elinav, Eran, additional, Ferreira, Gilda A., additional, Fiocchi, Claudio, additional, Massó, Julio Raúl Fernández, additional, Furlan, Roberto, additional, Gironi, Maira, additional, Gresnigt, Mark S., additional, Haines, David D., additional, Italiani, Paola, additional, Lage, Agustin, additional, Levi-Schaffer, Francesca, additional, Migliorini, Paola, additional, Oliveira, Thiago H.C., additional, Penton-Arias, Eduardo, additional, Penton-Rol, Giselle, additional, Pevsner-Fischer, Meirav, additional, Puxeddu, Ilaria, additional, Rot, Chagai, additional, Sinh, Preetika, additional, Teixeira, Mauro M., additional, Töpfer, Elfi, additional, Tuganbaev, Timur, additional, and van de Veerdonk, Frank L., additional

Published
2016
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50. Mild neoterminal ileal post‐operative recurrence of Crohn’s disease conveys higher risk for severe endoscopic disease progression than isolated anastomotic lesions

Author

Bachour, Salam P., primary, Shah, Ravi S., additional, Lyu, Ruishen, additional, Rieder, Florian, additional, Qazi, Taha, additional, Lashner, Bret, additional, Achkar, Jean Paul, additional, Philpott, Jessica, additional, Barnes, Edward L., additional, Axelrad, Jordan, additional, Holubar, Stefan D., additional, Lightner, Amy L., additional, Regueiro, Miguel, additional, Cohen, Benjamin L., additional, and Click, Benjamin H., additional

Published
2022
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