1. Septic shock due to NSTI caused by Actinomyces Turicensis: the role of clinical pharmacology. Case report and review of the literature
- Author
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Laura Elisa Gasparini, Daniela Abbati, Milo Gatti, Francesco Scaglione, Roberto Fumagalli, Paolo Brioschi, Stefano Clemente, Chiara Grimaldi, Gatti, M, Gasparini, L, Grimaldi, C, Abbati, D, Clemente, S, Brioschi, P, Fumagalli, R, Scaglione, F, Gatti M., Gasparini L.E., Grimaldi C.M., Abbati D., Clemente S., Brioschi P.R., Fumagalli R., and Scaglione F.
- Subjects
0301 basic medicine ,medicine.medical_specialty ,Necrotizing soft tissue infection ,030106 microbiology ,Therapeutic drug monitoring ,Actinomycosi ,Actinomycosis ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,law ,Septic shock ,Antibiotic therapy ,Anti-Bacterial Agent ,Actinomyces Turicensi ,medicine ,Actinomyces ,Humans ,Pharmacology (medical) ,030212 general & internal medicine ,Actinomyce ,Intensive care medicine ,Pharmacology ,Clinical pharmacology ,medicine.diagnostic_test ,business.industry ,Soft Tissue Infections ,Clinical Pharmacology ,Middle Aged ,medicine.disease ,Shock, Septic ,Anti-Bacterial Agents ,Infectious Diseases ,Debridement ,Oncology ,NSTI ,Pharmacology, Clinical ,Ampicillin ,Female ,Actinomyces turicensis ,business ,Human - Abstract
Critical septic patients affected by necrotizing soft tissue infections (NSTI) require an early, aggressive and multidisciplinary treatment. Pharmacokinetic alterations in antibiotic therapy are peculiar in these infections. Clinical pharmacology represents a first step in this setting. We report a case of septic shock due to NSTI in which clinical pharmacology is taken into account.
- Published
- 2017