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Background: There is a limited number of studies assessing the alterations in nerve function impairment (NFI) in leprosy over an extended period of time. To the best of our knowledge, no published study has evaluated neurological state longitudinally during treatment utilizing a combination of clinical, functional (activity limitation), electrophysiological, and patient‐reported quality of life (QOL) outcomes. Methods: This prospective, observational study included leprosy patients of all spectra. Over 1 year of treatment, cutaneous and neurological examinations were done in addition to a nerve conduction study (NCS) and sympathetic skin response (SSR) assessment. QOL and activity limitation assessments using the World Health Organization Quality of Life brief version (WHOQOL–BREF) and Screening of Activity Limitation and Safety Awareness scale (SALSA), respectively, were also performed. Results: Out of 63 leprosy patients, loss of sensation was noted in 43 (68.2%) at baseline. At the completion of treatment, proportionate change revealed no change in 18 (28.5%), restored function in 9 (14.2%), improved status in 34 (53.9%), and deteriorated NFI in only 2 (3.1%) cases. The association between NCS‐SSR abnormalities was significant for a longer duration of disease at presentation (P = 0.04), in multibacillary cases [OR 9.12 (95% CI, 1.22–67.93)], in those in reaction [OR 3.56 (95% CI, 0.62–20.36)] and in those aged over 40 [OR 1.93 (95% CI, 0.28–13.41)]. There was an improvement in WHOQOL‐BREF and SALSA scores at release from treatment (P = 0.005 and P = 0.01, respectively). Conclusion: The majority of leprosy patients on treatment show improvement in NFI at the completion of therapy. However, change is influenced by critical factors such as bacillary load, disease duration, age, and the presence of reaction(s). [ABSTRACT FROM AUTHOR]

The aim of this study was to compare the sexual function of women with and without pregnancy-related PGP, and to investigate its relationship with physical activity (PA), kinesiophobia, and body image (BI). Demographic characteristics, sexual function (Pregnancy Sexual Response Inventory), PA (Pregnancy Physical Activity Questionnaire), kinesiophobia (Tampa Kinesiophobia Scale), and BI (Body Image in Pregnancy Scale) of 125 pregnant women were recorded. In the PGP group (n = 46), visual analogue scales were used to assess the pain intensity during resting and sexual activity, and Pelvic Girdle Questionnaire was used to evaluate the activity limitation. Although total sexual function and BI scores of the groups were similar (p > 0.05), dyspareunia during pregnancy and level of kinesiophobia were higher, and energy expenditure during moderate-intensity PA was lower in pregnant women with PGP (p < 0.05). The PGP group had moderate activity limitation and reported increased PGP intensity during sexual activities (p < 0.001). PA level was significantly correlated with sexual desire (r = 0.180), and overall sexual function was correlated with kinesiophobia (r = -0.344) and BI (r = -0.199) during pregnancy (p < 0.05). These findings suggest that pregnant women with PGP are more vulnerable to sexual dysfunctions, and there is a need to develop biopsychosocial framework-oriented management strategies which aim to improve PA level and to eliminate psychological factors such as kinesiophobia and negative BI. Clinical Trial Registration: NCT05990361 [ABSTRACT FROM AUTHOR]

Knowledge of specific activity limitations due to cold hypersensitivity is sparse. To explore activity limitations caused by cold hypersensitivity and the associated environmental factors in patients with hand injuries. Descriptive study. Seventy-seven patients with multiple tissue hand injuries described activity limitations related to cold hypersensitivity in questionnaires six and/or 12 months after surgery. To characterize the activity limitations, we performed a quantitative content analysis applying the International classification of functioning and health (ICF). The respondents described on average 3.6 cold related activity limitations in leisure and/or work. The activities were most frequently (n) assigned to the ICF domains d920 Recreation and leisure (95), d440 Fine hand use (77), and d850 Remunerative employment (39). The most common related environmental factors were Products and technology for e140 Culture, recreation and sport (79) and for e135 Employment (71), respectively, and e225 Climate (71). Gloves were both a facilitator and a barrier for activity performance. The impact of cold hypersensitivity on activity was related to both the activity and the environment. The results call for clinical interventions and product development, for example of gloves, to help patients solve their cold related activity limitations. • Several activity limitations due to cold hypersensitivity were reported. • Cold hypersensitivity affected both fine and gross motor activities. • The ICF-domains Fine hand use and Recreation and leisure were typically affected. • Climate was the environmental factor most commonly related to activity limitations. • Gloves or mittens could both facilitate and hinder activity performance. [ABSTRACT FROM AUTHOR]

AbstractPurposeMaterial and methodsResultsConclusion\nIMPLICATIONS FOR REHABILITATIONTo translate and cross-culturally adapt The Brachial Assessment Tool (BrAT) into Danish and assess its content validity and reproducibility in adults with traumatic brachial plexus injury (BPI).Translation followed international guidelines. BrAT(DK) were cognitive tested with 19 adults with traumatic BPI to evaluate cross-cultural understanding, relevance, comprehensiveness and comprehensibility. Content validity and reproducibility were evaluated following the COnsensus-based Standards for the selection of health Measurement INstruments guideline. Participants were recruited from an outpatient hand clinic. Test-retest reliability was assessed using intra-class-correlation coefficient (ICC) and the smallest detectable change (SDC). Internal consistency was evaluated using Cronbach’s alpha.Minor cultural differences were observed in the content validity analysis of BrAT(DK). Cognitive testing revealing no significant issues. All participants found the items relevant and important. 63 participants with traumatic BPI were recruited; 49 completed the retest. ICC values for the sub-scales and the total score ranged from 0.91 to 0.95 (95% CI 0.85 to 0.97). Internal consistency ranged from 0.87 to 0.98. SDC ranged from 4.16 to 9.63 for subscales and 16.01 for the total score.BrAT(DK) appeared to be content valid and reliabel as a measure of activity limitation in adults with traumatic BPI.The Brachial Assessment Tool (BrAT) has been cross-cultural translated into DanishBrAT(DK) shows adequate content validity for activity limitation in adults with traumatic brachial plexus injuryBrAT(DK) is a reliable measure, with a smallest detectable change of 16.01 points for the total scaleWe recommend the use of BrAT(DK) in clinical practice to inform goal setting and future interventions and treatment evaluationsThe Brachial Assessment Tool (BrAT) has been cross-cultural translated into DanishBrAT(DK) shows adequate content validity for activity limitation in adults with traumatic brachial plexus injuryBrAT(DK) is a reliable measure, with a smallest detectable change of 16.01 points for the total scaleWe recommend the use of BrAT(DK) in clinical practice to inform goal setting and future interventions and treatment evaluations [ABSTRACT FROM AUTHOR]

Perioperative counseling regarding activity limitations is critical for patients undergoing dermatologic surgery. Current postoperative instructions regarding activity limitations may be inadequate, but this cannot be determined without knowing patient expectations. The study objective was to elucidate patient expectations for counseling on postoperative activity limitations and to determine if increased counseling would impact patient planning pre or postoperatively. Patients who had excisions on the neck, torso, or extremities at one institution in one calendar year by the same surgeon participated in a phone survey. Questions addressed preexisting activity level, activity changes after surgery, amount of counseling received, and perioperative counseling expectations. Multivariable logistic regression was used to determine factors associated with patient perceptions about counseling, activity limitations, and surgical outcomes. Patients counseled on postoperative activity limitations reported they were unlikely to have made further arrangements to their surgical/personavl schedule had they been given additional counseling. The inverse was also true. When patients received the amount of counseling they expected, they were less likely to want to reschedule surgery or adjust personal plans. Younger patients and those with surgery on the lower extremities were more likely to limit their activity for longer periods of time. As instructions on activity limitations become more transparent, patients can make informed decisions regarding their surgical and personal schedules. This study can guide dermatologic surgeons in adjusting postoperative instructions to improve patient understanding of activity limitations, compliance, and the overall quality of their surgical experience. [ABSTRACT FROM AUTHOR]

The aim of this study was to examine the responsiveness of the Arabic Disabilities of the Arm, Shoulder and Hand (DASH) and to quantify its minimal important change (MIC) for improvement. People with upper extremity musculoskeletal problems who were receiving physical therapy were evaluated at baseline and again during a follow-up appointment, with a median time frame of 7 days between the two testing sessions (range of 6 to 72 days). The participants completed the Arabic DASH, Global Assessment of Function (GAF), Numeric Pain Rating Scale (NPRS) and Global Rating of Change Scale (GRC). The responsiveness of the Arabic DASH was assessed by examining the pre-specified hypotheses. The MIC for improvement was determined using the receiver operating characteristic method (MICROC) and the predictive modeling method (MICpred). As hypothesized, a change in the Arabic DASH demonstrated a significant positive correlation with changes in the GAF (r = 0.69), NPRS (r = 0.68) and GRC (r = 0.73). Consistent with our hypotheses, the DASH change scores could be used to differentiate between participants who improved and those who did not improve (area under the receiver operating characteristic curve = 0.87), and they showed a large magnitude of change (effect size = 1.53, standardized response mean = 1.42) in patients who improved. All the hypotheses specified a priori were supported by the results. The Arabic DASH MICROC and MICpred were estimated to be 14.22 and 14.85. The interaction between the DASH change and baseline score was not a significant predictor of status (improved vs. not improved) (p = 0.75), indicating that the DASH MIC was not baseline-dependent. The Arabic DASH demonstrated sufficient responsiveness, supporting the idea that the Arabic DASH is capable of detecting changes in upper extremity function over time. The value of the Arabic DASH MIC was similar when estimated using the predictive modeling and ROC methods, and the MIC was not dependent on baseline status. [ABSTRACT FROM AUTHOR]

in the performance of Activities of Daily Living (ADLs) and Instrumental Activities of Daily Living (IADLs), and the impact on their life satisfaction. Method: A quantitative cross-sectional study was conducted among 200 amputees at the Nsawam Orthopaedic Training Centre (OTC) in Ghana. The Groningen Activity Restriction Scale (GARS) and the Life Satisfaction Questionnaire-11 (LISAT-11) were used to collect data from the respondents. All statistical analyses were made using IBM Statistical Package for the Social Sciences (SPSS) software 23.0 and summarised in Tables. A multivariate analysis was used to establish the relationship between activity limitation and life satisfaction. Results: The respondents experienced some limitations in carrying out Activities of Daily Living and Instrumental Activities of Daily Living, with an overall mean activity limitation score of (36.57±10.93). They had moderate life satisfaction with a mean score of (3.86±1.15). A multivariate analysis revealed that there was a strong negative statistically significant relationship between activity limitations and life satisfaction (β =-0.13, p=0.000). Conclusion: The government of Ghana must explore these limitations through the Ministry of Health and its agencies who are involved in the management and rehabilitation of amputees. This would help inform decision-making in the planning and preparation of rehabilitation programmes, resource allocation, and policy formulation for amputees, in order to improve their overall satisfaction and well-being. [ABSTRACT FROM AUTHOR]

We examined self-reported reasons for activity limitations among Korean community-dwelling stroke survivors, focusing on age and sex differences. Data from 1547 stroke survivors who participated in the Korean National Health and Nutrition Examination Survey were analysed. The study outcomes were the self-reported reasons for activity limitations, encompassing general medical factors and stroke-related problems. These reasons were compared by age (<65 vs. ≥65 years) and sex using a complex-sample chi-square test. Stroke survivors reported different musculoskeletal, medical, and neurological problems as reasons for activity limitations, which differed by age and sex. Older stroke survivors reported more problems related to dementia, memory loss, auditory problems, back or neck problems, arthritis, or leg pain than younger survivors. Women reported more psychiatric problems, headaches or dizziness, back or neck problems, arthritis, gastrointestinal problems, and dental or oral problems than men. Older and female stroke survivors reported a higher mean number of reasons for activity limitations compared to younger and male survivors. Thus, a tailored approach considering age and sex is necessary to help stroke survivors with activity limitations in the Korean community. This study highlights the importance of considering demographic factors when designing interventions to improve their quality of life. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Physical Medicine & Rehabilitation Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Purpose: To determine the effect of trunk and arm impairments on physical and technical performance during wheelchair rugby (WR) competition. Methods: Thirty-one highly trained WR players grouped according to their trunk (no trunk [NT]; some trunk [T] function) and arm impairments (poor, moderate, and good arm function) participated in 5 WR matches. Players' physical (wheelchair mobility) and technical (ball handling) activities were analyzed using an indoor tracking system and video analysis, respectively. Results: Trunk impairment explained some of the variance in physical (10.6–23.5%) and technical (16.2–33.0%) performance. T covered more distance, had more possession, scored more goals, and received and made more passes yet spent less time at low speeds and performed fewer inbounds than NT (≤.05). Arm impairment explained some of the variance in all physical (16.7–47.0%) and the majority of technical (13.1–53.3%) performance measures. Moderate and good arm function covered more distance, reached higher peak speeds, spent more time in higher speed zones, scored more goals, had more possession, and received and made more passes, with a higher percentage of 1-handed and long passes, than poor arm function. Good arm function also received more passes and made a higher percentage of 1-handed passes and defensive blocks than moderate arm function (P ≤.05). Conclusions: Arm impairment affects a greater number of physical and technical measures of performance specific to WR than trunk impairment during competition. Having active finger function (good arm function) yielded no further improvements in physical performance but positively influenced a small number of technical skills. [ABSTRACT FROM AUTHOR]

Abstract Background A fifth of adults in low- and middle-income countries (LMICs) have multimorbid conditions, which are linked to socio-economic deprivation and aging. Multimorbidity is associated with high rates of functional problems and disability, increased healthcare utilization, and lower quality of life. Literature on multimorbidity and associations with function is mostly from high-income countries (HICs) and focused among older adults. Moreover, data regarding disease patterns and their impact on person-centered outcomes are limited. There is a need for research into understanding common patterns of multimorbidity, and their association with functional impairments, particularly in LMICs. Such information may contribute towards evidence-based and context-relevant strategic policy, planning, and delivery models for health and rehabilitation services, which is imperative in attaining Universal Health Coverage (UHC). The planned scoping review aims to provide an overview of the scope and nature of existing literature on multimorbidity patterns and function among adults in LMICs. Methods A scoping review will be conducted using a five-step framework and reported according to the PRISMA-ScR guidelines. A comprehensive electronic search of PubMed/MEDLINE, Scopus, EBSCOhost, Scielo, Cochrane and Google Scholar will be conducted and updated from the last pilot search ran in September 2020. Studies of any design will be included if they are reported in English, published (between January 1976 and the last search date) in a peer-reviewed journal, and describe multimorbidity patterns and associations with physical functional impairments, activity limitations or participation restrictions among adults in LMICs. Search results will be independently screened by two reviewers and data extraction will cover study characteristics, participants’ characteristics, multimorbidity measures, patterns analysis, and functional measures. Descriptive statistics and narrative synthesis will be used to synthesize and summarize findings. Discussion Patients with multimorbidity have unique and cross-cutting needs, hence the need for integrated and person-centered approaches to policy, planning, and delivery of medical and rehabilitation services. Considering the shift towards UHC and primary healthcare-led management of chronic diseases, the proposed scoping review is timely. Findings will provide insights into the current extent and scope of multimorbidity research, and guide future inquiry in the field. Trial registration Open Science Framework (OSF), https://osf.io/gcy7z/

Abstract Background Osteoarthritis (OA) and Rheumatoid arthritis (RA) are the most common joint diseases leading to chronic pain and disability. Given the chronicity and disabling nature of OA and RA, they are likely to influence full participation of individuals in the society. An activity limitation occurs when a person has difficulty executing an activity; a participation restriction is experienced when a person has difficulty participating in a real-life situation. The aim of this study was to examine the associations between OA and RA and the domains of activity limitation and participation restriction. Methods A cross-sectional study design comprised 3604 adults from the 2009 to 2018 National Health and Nutrition Examination Survey (NHANES). All participants aged ≥ 20 years with complete data were included. Activity limitation and participation restriction were assessed by reported difficulty in performing 14 tasks selected from Physical Functioning Questionnaire. Data on OA and RA were obtained from Medical Conditions Questionnaire. Weighted logistic regression model was used to examine the associations between OA and RA and the selected tasks. Results Over 36% of participants had limitations. Both OA (OR = 2.11) and RA (OR = 2.36) were positively associated with activity limitation and participation restriction (p

To translate and cross-culturally adapt the original Duke Activity Status Index (DASI) into the Arabic language and examine its psychometric properties in Arabic speaking patients with Chronic Obstructive Pulmonary Disease (COPD). The DASI was translated into the Arabic language and tested on 70 Arabic patients with COPD. Patients with COPD completed also the Six-Minute Walk Test (6MWT) and Saint George Respiratory Questionnaire (SGRQ) on the first visit. On the second visit, the patients with COPD completed the Arabic version of DASI along with the global rating of change scale (GRC). The internal consistency, test-retest reliability and construct validity were examined. Seventy Arabic speaking patients with COPD (56 males), mean (SD) age was 63.2 (11.1) year, completed the study. The patients reported no difficulty in understanding and completing the scale. Three items were modified and adapted to the Arabic culture. The Cronbach's alpha was 0.87, and the ICC2,1 was 0.95. The Arabic version of DASI correlated with the 6MWT (r = 0.55), the total score of SGRQ (r = −0.64) and its activity domain (r = −0.67), all p < 0.001. The Arabic version of DASI is a simple, quick, reliable, and valid measure of functional capacity in Arabic speaking patients with COPD. The Arabic DASI can be used in all Arabic-speaking countries given that the scale was adapted to standard Arabic language. The Arabic DASI would yield similar scores with administrations over time in patients with unchanged condition and stable COPD. This questionnaire could be used for screening of functional capacity in COPD in primary care settings. [ABSTRACT FROM AUTHOR]

Although systematic reviews have already been conducted on violence and disability, the evidence is not conclusive in Intimate Partner Violence (IPV). This study examined the prevalence of IPV in women with disabilities, taking account of the different types of violence and disability. We performed a search in five databases. We included observational studies that analysed the frequency of IPV in women with disabilities compared to women without. Two independent reviewers selected and assessed studies. We made a qualitative synthesis according to the type of IPV analysed in relation to disability. We identified 26 articles. The frequency and risk of IPV were greater in women with disabilities than in those without. All of the articles that studied financial violence, 81.3% of those that studied physical violence, 78.5% of those that studied psychological violence, 75% of those that studied physical/sexual violence, 73.3% of those that studied sexual violence and 50% of those that studied any type of violence found a significant association whit disability. Women with disabilities are at higher risk of IPV. Rehabilitation centers and its professionals must have a leading role in the identification of these situations and this should be considered in IPV prevention plans. People with disabilities are at higher risk of multiple types of violence. Violence against women with disabilities therefore involves two public health issues interacting simultaneously. Rehabilitation centers and its professionals should have a leading role in the identification of IPV in women with disabilities. IPV prevention plans should consider rehabilitation centers and its professionals as a main component of interventions in women with disabilities. [ABSTRACT FROM AUTHOR]

Mulualem Endeshaw Zeleke, Wubie Birlie Chekol, Habtamu Getinet Kassahun, Zemenay Ayinie Mekonnen Department of Anesthesia, University of Gondar, Gondar, Northwest, EthiopiaCorrespondence: Wubie Birlie Chekol, Email birliewubie@gmail.comBackground: Assessment of preoperative functional disability is vital for health status information. It is associated with an increase in perioperative risk of morbidity and mortality. Preoperative period is a critical time to enhance patient’s functional recovery. So, this study aimed to assess the prevalence and associated factors of preoperative functional disability among patients scheduled for elective surgery.Methods: Institution-based, multi-center, cross-sectional study was conducted in three Northwest Ethiopia referral hospitals from April 2021 to June 2021. Patients who scheduled for elective surgery in surgical, orthopedic, gynecology and ophthalmology wards were interviewed with semi-structured questionnaires. Functional disability was assessed by using a 12-item World Health Organization Disability Assessment schedule. Data were analyzed by SPSS version26.0. Binary logistic regression analysis was used to determine the associated variables.Results: A total of 403 patients who scheduled for elective surgery with mean age of (43.21 ± 16.18) years were included. The prevalence of preoperative functional disability was 34.5% (95% CI: 29.8, 39). Alcohol consumption (AOR: 2.05, 95% CI; 1.11, 3.77), malnutrition (AOR: 6.85, 95% CI; 3.06, 15.33), pain (AOR: 2.26, 95% CI; 1.28, 3.99) and depression (AOR: 7.90, 95% CI; 4.16, 15.01) were significantly associated with functional disability.Conclusion: The prevalence of preoperative functional disability was high. Alcohol consumption, nutritional deficiency, pain and depression were among the modifiable risk factors. So, added vigilance is needed in patients with these modifiable risk factors before surgery.Keywords: preoperative assessment, activity limitation, patient health questionnaire

Introduction: Dyspnea or shortness of breath is one of the cardinal features of chronic respiratory diseases (CRDs). It is a subjective symptom, frequently influenced by the state of mind of the patient. Kinesiophobia, excessive, irrational fear of physical movement due to dyspnea, often prevents patients from performing activities of daily living leading to physical deconditioning. The identification of relationship of dyspnea-related kinesiophobia and activity limitation can help guide patient management to improve quality of life, physical independence, and prevent physical deconditioning. Patients and Methods: The study was conducted using convenience sampling at a tertiary care hospital on 18–60-year-old patients with CRDs with dyspnea. Breathlessness Belief Questionnaire (BBQ) was used to evaluate dyspnea-related kinesiophobia. Activity limitation was assessed using Dyspnea Barthel Index (DBI). The scores of both scales were calculated, and the correlation between dyspnea related kinesiophobia and activity limitations was obtained using the Spearman's correlation. Results: Sixty subjects, 23 females and 37 males, were recruited. The mean (± standard deviation [SD]) age of the patients was 48.9 ± 12.5 years. Mean ± SD scores of BBQ were 58.4 ± 4.5. The mean score for DBI was 21.5 ± 2.12, and the average duration of the disease was 2 ± 0.707 years. Spearman's rank correlation coefficient between BBQ and DBI obtained was ρ = 0.712 with a P < 0.001. Conclusion: There is a strong correlation between dyspnea-related kinesiophobia and activity limitation in patients with CRDs.

To examine the psychometric properties of the Arabic version of the Lower Extremity Functional Scale (LEFS-Ar) in people with chronic obstructive pulmonary disease (COPD). Stable individuals with COPD (N = 70) confirmed by spirometry were asked to complete the LEFS-Ar, St George's Respiratory Questionnaire (SGRQ) and performed the Six-Minute Walk Test (6MWT). Participants were also asked to complete LEFS-Ar for the second time within 10 days. The LEFS-Ar floor and ceiling effects, internal consistency, test–retest reliability, measurement error, and construct validity were examined. The LEFS-Ar had excellent internal consistency with Cronbach's alpha of 0.95 and excellent test–retest reliability (ICCagreement=0.91) with no floor and ceiling issues. Standard error of measurement was 4.78 points while the minimal detectable change at 90% confidence was 11.15 points. Consistent with our hypotheses, the LEFS-Ar scores correlated significantly with 6MWT (r= −0.66, p < 0.001), activity domain of the SGRQ (r = 0.55, p < 0.001), and were significantly different according to COPD disease severity (p= 0.02). In people with COPD, the LEFS-Ar has excellent reliability with no floor or ceiling effects. The LEFS-Ar demonstrated evidence supporting its validity as a measure of activity limitation that can be used in clinical practice and in research studies. The Arabic version of the Lower Extremity Functional Scale (LEFS-Ar) is a reliable measure in people with chronic obstructive pulmonary disease (COPD). Rehabilitation specialists can use the LEFS-Ar to validly measure activity limitation in people with COPD. [ABSTRACT FROM AUTHOR]

Background. Diseases of the circulatory system continue to hold a leading position as a cause of morbidity in the population. Emerging сomplications of diseases of the circulatory system are associated with persistent impairment of health and of Work capacity which is the basis for determining disability. Purpose. An in-depth analysis of primary disability indicators in the adult population of Moscow due to diseases of the circulatory system. Materials and methods. The object of the study was “Information on the medical and social examination of persons aged 18 and over” (form 7-social security 2013-2019). Research methods: documentary, copy of the data, statistical and graphic. Statistical data processing was performed using the Statistica 10 and SAS JMP 11 software package. Results. In the nosological structure of primary disability of the adult population of Moscow due to diseases of the CVD, the first ranking place was taken by peaple who were newly recognized as disabled (PNRD) due to cerebrovascular diseases (CVD), the second – PNRD due to coronary heart disease, the third – PNRD due to “Other diseases of the circulatory system“. Men PNRD and elderly PNRD prevailed in the age-sex structure of primary disability. The greatest differences between nosological contingents were revealed in terms of the proportion of various types of activity limitations of the third degree, which predominantly took place among PNRD due to CVD. The prevailing group of disability was III group. Conclusion. The revealed features of the dynamics and structure of disability due to diseases of the circulatory system are advisable to use when planning measures to improve the effectiveness of medical and social rehabilitation of disabled people due to this socially significant pathology.

Objective: This study aims to identify associations between nocturnal asthma awakenings and functional health outcomes in a cohort of teenagers with asthma. Methods: We analyzed baseline data from teenagers enrolled in SB-ACT, an NIH-funded RCT. During an at-home baseline survey, teenagers with asthma answered questions about demographics, recent asthma symptoms, and functional health outcomes. We conducted regression analyses to explore the relationship between persistent nocturnal asthma symptoms (≥2 nights of nocturnal asthma awakenings in the past 14 days) and functional health measures. Results: Of the 430 teens enrolled (Participation rate = 79%, Mean Age = 13.4), 30% reported persistent nocturnal asthma symptoms. Compared to teens with intermittent nocturnal asthma symptoms, teens with persistent nocturnal asthma symptoms were more likely to report physical limitation during strenuous activities (OR = 1.9, 1.3–3.0), moderate activities (OR = 1.9, 1.2–3.1), and school gym (OR = 2.4, 1.5–3.8). They were also more likely to report depressive symptoms (OR = 2.3, 1.5–3.6), more asthma-related school absenteeism in the past 14 days (0.81 vs 0.12, p < 0.01) and poorer quality of life (4.6 vs 5.9, p < 0.01). These findings remained significant when controlling for daytime asthma symptoms, weight status, race, ethnicity, gender, age, and smoke exposure. Conclusions: In this cross-sectional study, persistent nighttime asthma symptoms were associated with poor functional health outcomes among teens, independent of day-time symptoms. Identifying nighttime symptoms and improving asthma control at night may positively impact daily functioning for these teens. [ABSTRACT FROM AUTHOR]

Assistive technologies (AT) can compensate for activity limitations and loss of physical functioning. Little is known regarding how minority older adults differ in AT use as they age. This study examined race and ethnic differences in AT use among a nationally representative sample of older adults in the United States. Weighted logistic regression analyses were conducted using the 2012 Behavioural Risk Factor Surveillance System (BRFSS), collected annually by the Centres for Disease Control and Prevention (CDC). The study sample included 282,825 non-Hispanic White, African American, Asian and non-White Hispanic older adults. Activity limitation, health care access, overall health status and sociodemographic characteristics were included as variables in the analysis. Interaction analyses were conducted to examine the moderating effect of race/ethnicity on social determinants with AT use. Results indicated that 13.5% of older adults reported the use of an AT. African American older adults had the highest percentage of AT use (21.0%), and Asian older adults had the lowest (5.1%). Those who were 85 years and older, reported an activity limitation, were unmarried and in poor health were most likely to use an AT. Having health insurance was significantly associated with higher AT use for non-Hispanic Whites (OR = 1.66, p < 0.001) and non-White Hispanics (OR = 1.98, p < 0.01), but not African Americans and Asians. Health professionals can promote access and address barriers in AT use, particularly in regard to accessibility and acceptability among minority older adults. African-Americans older adults were most likely to use ATs, and Asian older adults the least Older adults who were 85 years and older, reported an activity limitation, were unmarried and in poor health were most likely to use an AT Different social determinants to AT use were found among race/ethnic groups, highlighting the need to promote access and address barriers to health care utilization [ABSTRACT FROM AUTHOR]

Background: Osteoarthritis (OA) and Rheumatoid arthritis (RA) are the most common joint diseases leading to chronic pain and disability. Given the chronicity and disabling nature of OA and RA, they are likely to influence full participation of individuals in the society. An activity limitation occurs when a person has difficulty executing an activity; a participation restriction is experienced when a person has difficulty participating in a real-life situation. The aim of this study was to examine the associations between OA and RA and the domains of activity limitation and participation restriction.Methods: A cross-sectional study design comprised 3604 adults from the 2009 to 2018 National Health and Nutrition Examination Survey (NHANES). All participants aged ≥ 20 years with complete data were included. Activity limitation and participation restriction were assessed by reported difficulty in performing 14 tasks selected from Physical Functioning Questionnaire. Data on OA and RA were obtained from Medical Conditions Questionnaire. Weighted logistic regression model was used to examine the associations between OA and RA and the selected tasks.Results: Over 36% of participants had limitations. Both OA (OR = 2.11) and RA (OR = 2.36) were positively associated with activity limitation and participation restriction (p < 0.001). Poor or fair health was associated with difficulty in physical functioning, with highest odds observed in leisure activities (OR = 2.05), followed by difficulty in attending social events (OR = 1.99), walking for a quarter mile (OR = 1.97), preparing meals (OR = 1.93) and walking up ten steps (OR = 1.92).Conclusion: Adults with OA and RA had nearly similar odds of having activity limitations and participation restrictions. Difficulty in executing most activities of daily living (ADLs) has significant association with poor or fair health. Holistic interdisciplinary care to individuals with OA or RA focusing on ADLs and environmental factors may improve health status. [ABSTRACT FROM AUTHOR]

Background: A fifth of adults in low- and middle-income countries (LMICs) have multimorbid conditions, which are linked to socio-economic deprivation and aging. Multimorbidity is associated with high rates of functional problems and disability, increased healthcare utilization, and lower quality of life. Literature on multimorbidity and associations with function is mostly from high-income countries (HICs) and focused among older adults. Moreover, data regarding disease patterns and their impact on person-centered outcomes are limited. There is a need for research into understanding common patterns of multimorbidity, and their association with functional impairments, particularly in LMICs. Such information may contribute towards evidence-based and context-relevant strategic policy, planning, and delivery models for health and rehabilitation services, which is imperative in attaining Universal Health Coverage (UHC). The planned scoping review aims to provide an overview of the scope and nature of existing literature on multimorbidity patterns and function among adults in LMICs. Methods: A scoping review will be conducted using a five-step framework and reported according to the PRISMA-ScR guidelines. A comprehensive electronic search of PubMed/MEDLINE, Scopus, EBSCOhost, Scielo, Cochrane and Google Scholar will be conducted and updated from the last pilot search ran in September 2020. Studies of any design will be included if they are reported in English, published (between January 1976 and the last search date) in a peer-reviewed journal, and describe multimorbidity patterns and associations with physical functional impairments, activity limitations or participation restrictions among adults in LMICs. Search results will be independently screened by two reviewers and data extraction will cover study characteristics, participants' characteristics, multimorbidity measures, patterns analysis, and functional measures. Descriptive statistics and narrative synthesis will be used to synthesize and summarize findings. Discussion: Patients with multimorbidity have unique and cross-cutting needs, hence the need for integrated and person-centered approaches to policy, planning, and delivery of medical and rehabilitation services. Considering the shift towards UHC and primary healthcare-led management of chronic diseases, the proposed scoping review is timely. Findings will provide insights into the current extent and scope of multimorbidity research, and guide future inquiry in the field. Trial registration: Open Science Framework (OSF), https://osf.io/gcy7z/ [ABSTRACT FROM AUTHOR]

Introduction: Irritable bowel syndrome is the most common, costly, and disabling dysfunction of the gastrointestinal tract. Mental disorders can be one of the main factors in the onset, continuation, or exacerbation of gastrointestinal signs and symptoms in people with this syndrome. Commitment and acceptance therapy is a mixture of four approaches of awareness, acceptance, commitment, and behavior change, and its overall goal is to achieve psychological flexibility to move towards thought-based behavior. This treatment focuses less on reducing symptoms and more on improving the quality of life. Objective: This study aimed to determine the effectiveness of acceptance and commitment-based therapy on the immune function and activity limitations in patients with irritable bowel syndrome. Materials and Methods: This study was a quasi-experimental research with a pre-test, post-test design and a control group. Thirty patients with irritable bowel syndrome were randomly selected from those referred to a hospital clinic in Tabriz City, Iran. They were randomly divided into the intervention and control groups (15 in each group). The intervention group received acceptance and commitment group therapy for 8 sessions, while the control group did not receive any intervention. Both groups were assessed before and after the intervention, and in the follow-up phase using the activity limitations subscale of quality of life questionnaires (to measure activity limitations) and stool calprotectin test to assess safety performance. Data analysis was performed using descriptive statistics indices (mean and standard deviation) and analysis of variance with repeated measures, Bonferroni test, and analysis of covariance to test the study hypotheses. Results: The Mean±SD age of the intervention group was 34.53±18.38 years, and the Mean±SD age of the control group was 42.80±17.97 years. The significance levels of Levene’s and the Shapiro-Wilk test for all variables were greater than 0.05. Based on the results, the Mean±SD score of the activity limitations variable in the intervention group was 7.53±4.24 in the pre-test, 17.66±3.41 in the post test, and 17.26±3.65 in the follow-up. According to the results, activity limitations (P=0.027) and safety performance (P=0.034) were significantly different before and after the intervention. Conclusion: The present study’s findings show that acceptance and commitment-based therapy can play an influential role in improving patients’ immune function and promoting their activity limitations. Therefore, this treatment is recommended as a complementary therapy in patients with irritable bowel syndrome.

Objective: To investigate the effect of virtual reality on arm motor impairment, activity limitation, participation restriction, and quality of life in patients with stroke. To determine potential moderators that affect the efficacy of virtual reality. Data sources: CINAHL, Medline, PubMed, EMBASE, Cochrane Library, Chinese National Knowledge Infrastructure, and Wanfang Data from inception to October 23, 2021. Review methods: Randomized controlled trials that investigated the effect of virtual reality on arm recovery in adult patients with stroke compared to conventional therapy or sham control were included. Physiotherapy Evidence Database Scale was used to assess the methodological quality of each study. Results: Forty studies with 2018 participants were identified. Quality of included studies was fair to high. Virtual reality exhibited better effects on overall arm function (g = 0.28, p < 0.001), motor impairment (g = 0.36, p < 0.001) and activity limitation (daily living) (g = 0.24, p < 0.001) compared with the control group. No significant improvement was observed in participation restriction and activity limitation (specific task). The result for quality of life was described qualitatively. Subgroup analyses demonstrated that immersive virtual reality produced a greater beneficial effect (g = 0.60, p < 0.001). Patients with moderate to severe arm paresis could make more progress after training (g = 0.71, p < 0.001). Conclusion: Virtual reality is recommended for improving motor impairment and activities of daily living after stroke and is favorable to patients with moderate to severe paresis. An immersive design could produce greater improvement. [ABSTRACT FROM AUTHOR]

Activity limitations can diminish life satisfaction. This study explored the role of optimism on the relationship between changes in activities of daily living and instrumental activities of daily living (ADL/IADL) limitations and life satisfaction over time among middle-aged and older adults. Growth curve modeling accounting for intra- and inter-individual changes in life satisfaction was applied to the 2008–2018 waves of the Health and Retirement Study Leave Behind Survey subsample (n = 39,122 person-years). After controlling for sociodemographic factors, physical functioning decline adversely affected life satisfaction (β ADL = −0.12, β IADL = −0.13, p < 0.001), but the negative consequences reduced slightly through optimism (β ADL = −0.11, β IADL = −0.12, β optimism = 0.47, p < 0.001). Increasing optimism could reduce the negative consequences of ADL/IADL limitations on life satisfaction among middle-aged to older adults. [ABSTRACT FROM AUTHOR]

Background: In this article, self-perceived health in 11 European Union countries and Turkey was studied and the effects of socio-economic factors on self-rated health in Turkey were analysed. Methods: The percentage distributions of self-perceived health, chronic morbidity and activity limits in the health module of the Income and Living Condition Surveys conducted between 2008 and 2016 in the EU-28 and Turkey were analysed. The effects of income, education, work status, gender, marital status and age on self-perceived health, chronic morbidity and activity limitations were tested with stepwise binary logistic regression. Results: In the EU-28 and Turkey, 70%–75% of the population aged ≥ 16 years reported very good or good health, while the rate of chronic illness averaged around 30–35%. Socio-economic conditions in the EU-28 and Turkey affected self-perceived health and illness. It was found that income, education level, gender, employment status, marital status and age groups had significant effects on having a poor health status. Conclusion: The prevalence of chronic illness in more densely populated EU countries was above the EU-28 average. One in three people in the EU-28 and Turkey had at least one or more chronic conditions. The people in the bottom income quintile usually had the lowest education level in Turkey. These two significant factors coincided with negative health status, chronic conditions and daily activity limitations since health issues are more commonly observed in people with lower socio-economic status. Age was the most important determinant of chronic conditions in Turkey. For every 10 years of age, the risk of poor health and chronic illness increased exponentially. [ABSTRACT FROM AUTHOR]

Purpose: To study the impact of moderate and severe primary open-angle glaucoma (POAG) on the quality of life (QoL) due to activity limitation using glaucoma-specific questionnaires.Methods: This cross-sectional study enrolled 122 participants, 50% (n = 61) being controls and 50% were diagnosed cases of moderate/severe POAG. Three orally administered glaucoma-specific QoL instruments were used: Glaucoma Activity Limitation (GAL-9), Glaucoma Quality of Life (GQL-15), and Viswanathan questionnaires. The questions related to activity limitation were identified and analyzed for each questionnaire separately.Results: The mean age of the participants was 61.04 ± 9.88 years and a majority were males (64.8%, n = 79). The mean scores in controls, moderate glaucoma, and severe POAG patients for GAL-9 questionnaire were 9.77 ± 1.36 (P = 0.44), 13.75 ± 4.76 (P < 0.001), and 23.45 ± 5.62 (P < 0.001), for GQL-15, these were 16.39 ± 2.18 (P = 0.5), 22.75 ± 7.89 (P < 0.001), and 39.34 ± 9.42 (P < 0.001), respectively, while for the Viswanathan questionnaire, they were 9.49 ± 0.94 (P = 0.38), 7.91 ± 1.59 (P < 0.001), and 4.41 ± 2.20 (P < 0.001), respectively. The GQL-15 and GAL-9 questionnaires concluded that activity limitation pertaining to dark adaptation-related tasks affected the QoL the most in moderate as well as severe POAG (P < 0.001). Using the Viswanathan questionnaire, it was observed that the peripheral vision-related activity limitation was most significant for the decrease in QoL in moderate POAG while near vision-related activity limitation affected the QoL the most in severe POAG (P < 0.001).Conclusion: All three questionnaires concluded that the activity limitation due to moderate and severe glaucoma has a negative impact on the QoL. The limitation of the tasks involving dark adaptation/glare and peripheral vision has the most significant impact on the QoL in moderate glaucoma. As the disease progresses to a severe category, the limitation of activities requiring central and near vision causes the most significant worsening in QoL. [ABSTRACT FROM AUTHOR]

Purpose: Utilising Rasch analysis on the Keratoconus Outcome Research Questionnaire (KORQ) data, we explored the hypothesis that the KORQ with discrete verbal rating scale (VRS) would demonstrate better psychometric properties and provide less noise in measurement than with a visual analogue scale (VAS). Methods: The KORQ is a keratoconus‐specific patient‐reported outcome measure; it has activity limitation and symptoms scales. The KORQ scales with two different rating scales (VAS and a discrete 4‐response VRS) were completed by self‐administration by people with keratoconus. For each KORQ scale, Rasch analysis‐based psychometric properties were compared between the two versions. Rasch analysis was also used to optimise rating scale functioning when disordered thresholds were observed. Results: 118 (mean age ± SD, 46.4 ± 0.4 years) and 169 (45.4 ± 14.7 years) people completed the KORQ with VAS and VRS, respectively. Both scales demonstrated high measurement precision. However, the VAS rating scale was disordered (6 out of 11 categories dysfunctional) and had two misfitting items. Conversely, the VRS had ordered categories and no misfitting items. For the disordered VAS, ordering was achieved only after collapsing 11 categories into four categories. In comparison to the KORQ with VRS, the repaired VAS had lower measurement precision, test information, variance explained by the measure, poor targeting, and reduced measurement range. Conclusions: The KORQ demonstrated superior psychometric properties when measured using a VRS than with a VAS. This illustrates the advantages of verbal rating scales for a patient‐reported outcome measurement over a visual analogue scale. [ABSTRACT FROM AUTHOR]

Background: Since the introduction of antiretroviral therapy (ART), the incidence of HIV-associated dementia has drastically fallen. Despite using ART, people living with HIV continue to experience less severe but limiting forms of HIV-associated neurocognitive disorder (HAND). People living with HIV who are on ART and experiencing symptoms of HAND may benefit from aerobic exercise. Objective: This protocol describes a randomized controlled trial designed to determine the effects of a 12-week aerobic exercise program on HAND in Southeastern Nigeria. Methods: At least 68 patients diagnosed with HAND will be randomly placed into either an aerobic exercise group or control group. Patients in the aerobic exercise group will perform a moderate intensity workout on a stationary bicycle ergometer, 3 times a week for 12 weeks. We will measure the primary outcomes including neurocognitive performance, prevalence of HAND, viral load, and CD4 count. We will evaluate postexercise neurocognitive performance using reliable neuropsychological tests relevant to people living with HIV, in line with the Frascati criteria. We will assess secondary outcomes such as quality of life, activity limitation, and social participation using the World Health Organization Quality of Life (WHOQOL)-Brief, and the Oxford Participation and Activities questionnaire. We will use exploratory statistics to test the data for normality and homogeneity. We will analyze the effect of the exercise program on HAND using relative risk (RR) and absolute risk reduction (number needed to treat). Analysis of covariance will be run to estimate the effect of exercise on quality of life and activity and participation level. Results: This funded trial was approved by the Institutional Review Board in May 2020. The protocol was approved on June 15, 2020. Enrollment commenced in January 2021 and was completed in May 2021. Over 60% of the participants were recruited at the time of first submission to JMIR Mental Health. Data curation is still ongoing; hence, data analysis is yet to be executed. Study outcomes are expected to be published in March 2022. Conclusions: This is a protocol for a randomized controlled trial that aims to evaluate the effect of a 12-week aerobic exercise program on HAND in Southeastern Nigeria. [ABSTRACT FROM AUTHOR]

BACKGROUND: Functional disability develops in a dynamic and progressive manner. As people age, their health problems worsen and they lose the ability to perform activities of daily living (ADLs) such as dressing, using the toilet, bathing, and eating. With a better understanding of the underlying risk factors and the related mechanisms of the disablement process, it is possible to make more effective and more efficient programs to prevent or delay the onset of disability in older people. MATERIALS AND METHODS: A community-based, descriptive, cross-sectional study was carried out among 453 elderly from Tamil Nadu, India. A door-to-door interview was used to administer the Katz Index of Independence on ADL. Simple random selection was employed to select the study individuals. To determine the association for particular risk factors, Chi-squared test and binary logistic regression were used. RESULTS: First, our study findings show the prevalence of activity limitation among the elderly using the The Katz Index of Independence. This study shows that the prevalence of activity limitation was 23% among the elderly. Seventy-seven percent had no significant limitations: they are independent. There is a statistically significant association between activity limitation as opposed to gender, visual impairment, depression, urinary incontinence, unintentional injury in the past year, and alcohol consumption. CONCLUSION: The study found that the self-reported prevalence of activity limitation was 23% among the elderly and 77% had no significant limitations. The Katz Index of Independence in activities of daily living may be used as a handy tool to identify the activity limitation in community-based checkups.

Purpose: This study aimed to translate and adapt the Fear of Falling Avoidance Behavior Questionnaire (FFABQ) for Turkish culture and to evaluate the psychometric properties of FFABQ-Turkish in communitydwelling older adults. Methods: Eighty community-dwelling older adults (41 females) were assessed using the FFABQ-Turkish, Activities-specific Balance Confidence Scale (ABC). Fall history and severity of fear of falling (FoF) were recorded. Forty-two participants were reassessed one week apart for test-retest reliability. Internal consistency, test-retest reliability, sensitivity to change, convergent validity, construct validity, floor and ceiling effect, and scale discrimination of FFABQ-Turkish were investigated. Results: FFABQ-Turkish has high internal consistency and good test-retest reliability. Overall scores for FFABQ-Turkish were high in females, older individuals ≥ 75 years, and fallers. Minimal detectable change with 95% confidence was 4.51 points. There were strong and moderate correlations between FFABQTurkish and ABC, FoF, and the number of falls. Factor analysis demonstrated a two-factor structure. No floor and ceiling effect was found. FFABQ-Turkish could discriminate individuals without avoidance behavior from those with severe avoidance behavior. Conclusions: FFABQ-Turkish is a valid and reliable measure to assess the activity and participation restriction due to FoF, and could be used to quantify avoidance behavior in Turkish community-dwelling older adults. [ABSTRACT FROM AUTHOR]

Abstract Background Although identifying vulnerable groups is an important step in shaping appropriate and efficient policies for targeting populations of disabled people, it remains a challenge. This study aims to evaluate for the first time the comparability of the different disability measurements used in Cameroon. This is done by comparing them with the international standards proposed by the Washington Group (WG). It also evaluates the consistency of the association between the disability as measured by these surveys and the sociodemographic characteristics. Method We used data from the third Cameroonian Population and Housing Census (3RGPH) of 2005, the third Cameroonian Household survey (ECAM3) of 2007, the Demographic Health and Multiple Indicator Cluster Survey (DHS-MICS) of 2011 and a survey conducted on adults in Yaoundé (HandiVIH) in 2015 with the WG tool. The proportion and their confidence intervals, chi-square tests and multivariate logistic regressions are used for analyses. Results In the city of Yaoundé and for the 15–49 age group, disability prevalence was estimated at 3.6% (CI = [2.5, 5.1]), 2.7% CI = [2.1, 3.5]), 2.6% (CI = [2.4, 2.7]) and 1.0% (CI = [1.0, 1.10]), according to DHS-MICS, ECAM3, HandiVIH and 3RGPH, respectively. The prevalence of severe motor and mental disabilities in DHS-MICS (0.4% CI = [0.2, 0.8], 1.1% CI = [0.7, 1.8] and 0.5% CI = [0.2, 1.1], respectively) are not significantly different from the findings of HandiVIH (0.3% CI = [0.2, 0.3], 0.8% CI = [0.7, 0.9] and 0.5% CI = [0.5, 0.6], respectively). Only motor disability prevalence in ECAM3 (0.8%, CI = [0.5, 1.2]) is not different from that of HandiVIH. When the WG screening tool is used in HandiVIH, disability is positively associated with age, negatively associated with educational level, being in a union and socioeconomic status (SES) and it is not associated with sex. Severe disability, for its part, is not associated with SES and is positively associated with being a male. A different association trend is observed with 3RGPH, ECAM3 and DHS-MICS. Conclusion None of the instruments used in the nationally representative Cameroonian surveys produced both disability prevalence and association trends that are exactly similar to those obtained when using the WG disability screening tool, thus highlighting the necessity to include the WG questions in nationally representative surveys.

Introduction: The armed forces provide lifelong medical benefits to all their veterans. As most of them are older, their health needs are quite different from those of serving personnel. Having led a relatively active and disciplined life in the services, their general health might also be better than that of their civilian counterparts. Unfortunately, there are no data available on the health of Indian military veterans. This study was planned to ascertain the level of activity limitation (AL) and participation restriction (PR) and determine factors affecting AL and PR. Material and Methods: This community-based, cross-sectional study was conducted among 406 veterans and their spouses aged 60 years and above residing in an urban housing society. House-to-house surveys were conducted. The study was done over 6 months (July–December 2016). Ethical clearance and informed consent were taken. The questionnaire used in the study was designed by incorporating elements from the International Classification of Functioning, Disability, and Health questionnaire and the WHO Disability Assessment Schedule. Results: Of the 406 veterans and their spouses surveyed, 188 (46.3%) were male and 218 (53.7%) were female. The majority of them were in the age groups of 61–70 years (175, 43.1%) and 71–80 years (173, 42.6%). Most of them were living with other family members with only 59 (14.5%) living alone. AL score was good or average in most of them (263 and 124, respectively), and it was bad or very bad in only a small number (11 and 8, respectively) Similarly, the PR score was good or average in 316 and 78 participants, respectively. Only 12 (2.8%) had a bad PR score. PR score increased significantly beyond the age of 80 years (P = 0.00). AL was more in males as compared to females. PR was more in those who were not married/divorced/single (P < 0.05). AL and PR were independent of the type of caregivers (P > 0.05). The most common ailments reported by males were body aches and pains, hearing defects, and problems related to micturition. Complaints of feeling low or depressed were significantly higher in females (P < 0.05). The top five causes of morbidity in the study population were hypertension (209, 51.5%), diabetes (125, 30.8%), defective vision (116, 28.6%), cataract (105, 25.9%), and dental problems (102, 25.1%). Conclusion: This study provides an insight into the magnitude of disease, impairment, and disability among veterans. Hypertension was the most common morbidity. Assessment of the AL and PR is useful planning geriatric care and educating caregivers and families to improve the quality of life of the elders.

The impact of stroke on motor functioning is analyzed at different levels. 'Impairment' denotes the loss of basic characteristics of voluntary movement. 'Activity limitation' denotes the loss of normal capacity for independent execution of daily activities. Recovery from impairment is accomplished by 'restitution' and recovery from activity limitation is accomplished by the combined effect of 'restitution' and 'compensation.' We aimed to unravel the long-term effects of variation in lesion topography on motor impairment of the hemiparetic lower limb (HLL), and gait capacity as a measure of related activity limitation. Gait was assessed by the 3 m walk test (3MWT) in 67 first-event chronic stroke patients, at their homes. Enduring impairment of the HLL was assessed by the Fugl–Meyer Lower Extremity (FMA-LE) test. The impact of variation in lesion topography on HLL impairment and on walking was analyzed separately for left and right hemispheric damage (LHD, RHD) by voxel-based lesion-symptom mapping (VLSM). In the LHD group, HLL impairment tended to be affected by damage to the posterior limb of the internal capsule (PLIC). Walking capacity tended to be affected by a larger array of structures: PLIC and corona radiata, external capsule and caudate nucleus. In the RHD group, both HLL impairment and walking capacity were sensitive to damage in a much larger number of brain voxels. HLL impairment was affected by damage to the corona radiata, superior longitudinal fasciculus and insula. Walking was affected by damage to the same areas, plus the internal and external capsules, putamen, thalamus and parts of the perisylvian cortex. In both groups, voxel clusters have been found where damage affected FMA-LE and also 3MWT, along with voxels where damage affected only one of the measures (mainly 3MWT). In stroke, enduring 'activity limitation' is affected by damage to a much larger array of brain structures and voxels within specific structures, compared to enduring 'impairment.' Differences between the effects of left and right hemisphere damage are likely to reflect variation in motor-network organization and post-stroke re-organization related to hemispheric dominance. Further studies with larger sample size are required for the validation of these results. [ABSTRACT FROM AUTHOR]

Background Leprosy disease in the community is usually mistaken as a cursed disease. Leprosy disease is a chronic granulomatous infection caused by Mycobacterium leprae. Quality of life in leprosy patients with neuropathic pain in every region is varied. Objective To determine the quality of life in leprosy patients with neuropathic pain by using the SALSA Scale and VAS. Methods The research used analytic observational, a cross-sectional design and an interview technic. 37 subjects of 19 to 59 years age had leprosy with neuropathic pain at Donorojo Hospital. Results SALSA score explains that 62.2% of the research subject has limitation of activity and has a correlation with leprosy disease with p 0.012. There is no correlation between VAS score and leprosy disease with p 0.034. SALSA score and VAS score in this research explain there is no correlation with p 0.458. The number of other medical conditions with limitation activity has a correlation score of 0.870 which has a very good correlation power. The number of used tools with limitation activity has a correlation score of 0.716 which has a good correlation power. Conclusion There is activity limitation in leprosy patients with neuropathic pain at Donorojo Hospital Jepara District. The other aspect that affect activity limitation is the number of other medical conditions. Multibacillary type has more limitation than a Paucibacillary type. [ABSTRACT FROM AUTHOR]

Activity limitation is one of the most common causes of disability in people with knee and hip osteoarthritis (OA). The present study aimed to determine the reliability and validity of the Turkish adaptation of Animated Activity Questionnaire (AAQ) in patients with hip and knee OA. Two hundred knee and hip OA patients aged 18–80 were assessed using the AAQ. Internal consistency and test–retest measurements were performed to determine reliability. A subgroup of 40 patients completed the AAQ again after seven days to determine test–retest reliability. In order to validate Turkish version of the AAQ, all patients completed the AAQ, the Western Ontario and McMaster Universities Arthritis Index (WOMAC), Knee Injury and Osteoarthritis Outcome Score-Physical Function Shortform (KOOS-PS) and Hip Disability and Osteoarthritis Outcome Score-Physical Function Short form (HOOS-PS). Another subgroup of 136 patients performed the timed up and go (TUG) test, the 30-second chair stand test (CST), and the stair climbing test (SCT). The Cronbach alpha value of the AAQ was 0.94, demonstrating high internal consistency. The test–retest score of the AAQ was 0.97, which was also high. The AAQ exhibited negative and moderate correlation with the WOMAC, KOOS-PS and HOOS-PS (0.59, −0.60, and −0.49, respectively). Stronger and high correlations were determined between the AAQ and TUG, CST, SCT tests (-0.74, 0.62, and −0.58, respectively). The study findings suggest that the AAQ is a reliable and valid tool for evaluating activity limitations in Turkish knee and hip OA patients. [ABSTRACT FROM AUTHOR]

Background and Objective Activity is part of people’s daily lives, and activity limitation (AL) causes could be physical and mental problems. This study analyzes the causes of AL by sex and age group in adults. Material and Methods This study analyzed records surveyed using the Korea National Health and Nutrition Survey Questionnaire during 2013–2017. The subjects were 1597 men and 2249 women aged 30–79 years. The questionnaire assessed AL causes, and a chi-squared test analyzed age- and sex-based differences. Results Among the subjects, 45.8% men and 51.2% women reported AL occurrence. AL was prevalent among 18.5% men and 20.5% women in their 30s, and these numbers were correspondingly 60.9 and 60.6% for participants in their 70s. None reported one reported among men participants in their 30s. However, 3.2 and 3.9% of women in their 70s reported ≥3 AL causes. The most cause of AL for all ages is musculoskeletal problems. The main AL cause among people in their 30s was musculoskeletal and mental problems, whereas those in their 70s reported multiple causes, such as vision, hearing, respiratory, and musculoskeletal problems. Stroke, cancer, and hearing problem occurrences were significantly different between men and women, and women reported higher AL rate than men (p

Introduction: The primary purpose of this study was to examine the feasibility and informativeness of the Patient-Specific Functional Scale (PSFS) for identifying activities that persons with Parkinson disease (PD) self-identified as difficult.Method: Informativeness was investigated by cross-referencing the identified activities with the International Classification of Functioning, Disability, and Health (ICF), the Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS), and Parkinson's Disease Questionnaire (PDQ-39). Twenty-eight individuals with PD (Hoehn & Yahr stage 1–4) completed the PSFS. Activities identified by the participants were classified according to the ICF and then cross-referenced across the MDS-UPDRS and PDQ-39.Results: Participants identified 98 specific (60 different) activities that they were unable to do or were having difficulty with as a result of PD. Activities most frequently listed as difficult included some aspect of fine hand use, dressing, eating, or changing position (e.g. transferring). All activities could be classified using the ICF, but many were not addressed specifically by the MDS-UPDRS or PDQ-39.Conclusion: We conclude that the PSFS can be used for identifying activities that persons with PD personally find difficult and may be useful as a compliment to the MDS-UPDRS and PDQ-39. [ABSTRACT FROM AUTHOR]

Objective: Evaluate whether questionnaires identified all the self-reported patient outcomes raised in focus groups. Design: Mixed methods research combined with qualitative analysis of focus groups. Settings: Physical therapy clinic in a teaching hospital in Brazil. Subjects: A total of 27 patients (aged >18 years, mean age 55.2 years) with chronic non-specific low back pain. Interventions: Three focus groups were conducted by the same investigator and analyzed by meaning unit condensation. The results obtained from the focus groups were codified according to the International Classification of Functioning. A similar process was adopted to codify the Roland-Morris Disability Questionnaire, the Quebec Back Pain Disability Scale and the Oswestry Disability Index according to the International Classification of Functioning. The results of both coding processes were compared. Results: In the analysis, seven main concepts were identified, comprising 77 meaning units. Only three meaning units were not linked to the International Classification of Functioning. Most of the codes present in the questionnaires and focus groups represent limitations to activities. Some codes were identified in the questionnaires that were not mentioned by the focus group participants. No questionnaire assessed environmental factors or problems related to specific parts of the body, and very few assessed body function, all of which were issues raised in the focus groups. Conclusion: This study shows that not all fields considered important by patients to their function are being evaluated, and emotional and contextual factors should be included in clinical assessments in order to fully understand patient need. [ABSTRACT FROM AUTHOR]

Purpose: This study aimed to assess the level of activity limitation, and the factors associated with it, among people affected by leprosy who were reporting at a leprosy referral centre of Purulia, in West Bengal state, India. Method: A cross-sectional study was conducted among 358 individuals affected by leprosy. Persons recruited for this study were above 18 years of age, married, and had been diagnosed with leprosy for at least 1 year at the time of the interview. A semi-structured questionnaire was used to gather information about the respondents' socio-economic and disease status. The Screening of Activity Limitation and Safety Awareness (SALSA) Scale was used to measure activity limitation. Results: Of the 358 respondents, 59% were male, 60% were between 18 and 45 years of age, and 42% were illiterate. About 144 or 40% of the respondents had Grade 2 disability and 60% had disease duration of more than 3 years. There were 229 individuals (64%) who had no limitation in activities, 103 (29%) had mild limitation and 26 (7%) had moderate to severe limitation in activities. There is a significant association between gender, age, occupation, physical disability and disease duration with activity limitation. Conclusion: It appears that limitations in activities among persons affected by leprosy are associated with being a woman, a housewife, an aged person, and with longer disease duration. The physical disability was intrinsically associated with limitation in activities. [ABSTRACT FROM AUTHOR]

Background: Both pain interference and depressive symptoms have certain effects on dementia, and these are reciprocally related. However, comorbid effects of pain interference and depressive symptoms on dementia have not been examined in detail.Objective: This longitudinal study aimed to examine the combined effects of pain interference and depressive symptoms on the incidence of dementia in community-dwelling elderly individuals.Methods: This prospective cohort study with a 36-month follow-up period included 4,326 community-dwelling elderly individuals without dementia at baseline. Pain interference and depressive symptoms were assessed for every participant at baseline. We collected medical records in the Japanese public health insurance system to identify the incidence of dementia for 36 months.Results: The incidence rates of dementia during the follow-up period in the control, pain-interference, depressive-symptoms, and comorbid group were 3.2%, 6.2%, 7.9%, and 11.3%, respectively. A Cox regression analysis showed that the hazard ratios for the incidence of dementia were 1.85 (95% CI: 1.13-3.03) in the pain interference group, 1.87 (95% CI: 1.27-2.76) in the depressive symptoms group, and 2.20 (95% CI: 1.26-3.84) in the comorbid group, after adjusting for covariates.Conclusion: The coexistence of pain interference and depressive symptoms had a greater effect on the incidence of dementia than either condition alone in community-dwelling elderly individuals. Pain interference and depressive symptoms are known as common comorbid conditions and often form a negative cycle that accelerates the worsening of the individual symptoms of both. Thus, the comorbidity of these conditions may require monitoring for the prevention of dementia. [ABSTRACT FROM AUTHOR]

Objectives: Late-life depression, falls, and fall worry are public health problems. While previous research confirms the cross-sectional relationship between depression and fall worry, few longitudinal studies have examined whether changes in fall worry are associated with changes in depressive illness and vice versa. This study examined longitudinal relationships between probable major depression (PMD) and activity-limiting fall worry (ALW).Design, Setting, Participants, Measurements: This longitudinal panel observational study used data from the National Health and Aging Trends Study (NHATS) waves 5 (referred to as T1 in this study) and 6 (T2), conducted in 2015 and 2016, respectively (N = 6,299, aged 65 and older). We examined associations of new and continued ALW between T1 and T2 with T2 PMD, controlling for T1 PMD; and associations of new and continued PMD between T1 and T2 with T2 ALW, controlling for T1 ALW. We used χ2 and t tests for descriptive statistics and logistic regression for multivariable analysis.Results: Those with new ALW at T2 had significantly greater odds of T2 PMD compared to those without ALW at both time points (AOR = 2.64, 95% CI = 1.98-3.51), and those with new PMD at T2 had significantly greater odds of T2 ALW (AOR = 2.42, 95% CI = 1.66-3.52). Those with continued PMD also had greater odds of T2 ALW compared to those without PMD at either time point (AOR = 2.31, 95% CI = 1.62-3.29).Conclusions: The findings add to knowledge about bidirectional (mutually reinforcing) relationships between depression and activity-limiting fall worry. Innovative interventions are needed to reduce both late-life depression and activity-limiting fall worry. [ABSTRACT FROM AUTHOR]

Background: Vision impairment (VI) in older adults is associated with declines in well-being. However, the pathways through which poor vision leads to declines in well-being have not been well-described. The purpose of this study was to determine whether activity limitations and social participation restrictions mediate the impact of self-reported VI on subjective well-being.Methods: The National Health and Aging Trends Study (NHATS) is a nationally representative longitudinal study of Medicare beneficiaries 65 and older that includes detailed measures of the disablement process. A longitudinal mediation model was conceptualized linking self-reported VI and subjective well-being. Structural equation modeling was used to test the mediating effects of activity limitations and social participation restrictions while adjusting for relevant covariates.Results: The final sample included 5,431 respondents. At baseline, 8.0% of Medicare beneficiaries had self-reported VI. Subjective well-being scores were significantly lower among respondents with self-reported VI (15.7; 95% confidence interval [CI]: 15.2, 16.2) compared with those without VI (17.6; 95% CI: 17.5, 17.7). Self-reported VI had a significant indirect effect on subjective well-being through limiting mobility (β = -0.04; 95% CI: -0.07, -0.03) and household activities (β = -0.05; 95% CI: -0.08, -0.03), but not self-care limitations (β = 0.0; 95% CI = 0.0, 0.0) or participation restrictions (β = 0.0; 95% CI = -0.01, 0.00). Total indirect effects from all mediation paths accounted for 42% of the effect of VI on well-being.Conclusions: Mobility and household activity limitations are significant mediators that explain a considerable portion of the impact of poor vision on well-being. Interventions to promote successful accommodation may result in greater overall well-being for older adults with poor vision. [ABSTRACT FROM AUTHOR]

Abstract Background Studies have indicated that people with disabilities die earlier and may experience a poorer health than the general population. This study investigated 31 factors related to health and well-being, health behaviour and social relations among Danish adults with activity limitation (AL). Methods This study was based on data from the Danish Health and Morbidity Survey (DHMS) 2013 where 25,000 men and women aged 16 years or older were selected randomly from the adult Danish population. A total of 14,265 individuals answered the self-administered questionnaire including 100 questions on health-related quality of life, health behaviour, morbidity, consequences of illness and social relations. Based on an international standard question on AL, 888 individuals (6%) were defined as having profound AL and 4180 (29%) as having some AL. Multiple logistic regression analyses were used to analyse the associations between activity limitation and 31 indicators of health. The results were presented as relative risks 95% confidence intervals. Results Twenty-eight of 31 indicators showed consistently poorer health and well-being, health behaviour and social relations among individuals with AL as compared to individuals without AL. The increased relative risks were in a range of 7-661% the risk among individuals without AL. An example is obesity where RR (95% CI) was 2.07 (1.82–2.37). Only contact with internet friends was significantly higher among individuals with AL as compared to individuals with no AL. There was no association between alcohol and AL and no association between fast food and some AL. Conclusion Danish adults with AL experience a poorer health and well-being, and have an unhealthier lifestyle and poorer social relations than adults without AL. People with activity limitation should be prioritized in public health and efforts done to secure availability and flexibility of health care services and primary prevention programs. Policies should address accessibility, availability and affordability of health care and health behaviour among people with activity limitation.

Abstract Background Ageing is associated with a decline of motor function and ability to perform daily activities. Locomotive disorders are one of the major disorders resulting in adverse health condition in elderly people. Concept of Locomotive syndrome (LoS) was proposed to tackle the problems and prolong healthy life expectancy of people with locomotive disorders. To develop intervention strategy for LoS it is mandatory to investigate impairments, functional disabilities which people with locomotive disorder experience and to examine relationships among these parameters. For this purpose we have developed Geriatric Locomotive Function Scale-25 (GLFS-25). Though several physical performance tests were reported for identification or monitoring the severity of LoS, there are few studies reported on characteristics of disability which people with locomotive disorders experience. The aim of this study was to report the characteristics of ADL disabilities in elderly people with locomotive disorders in terms of numbers and degree of activity limitations. Methods We organized a cohort study and recruited 314 participants aged 65 years and over from five orthopedic clinics or nursing care facilities. This was a cross-sectional study to use the baseline data of such cohort. ADL disabilities were assessed using GLFS-25 scale arranging the GLFS-25 scores in ordinal levels using “R language” program. Numbers and degrees of activity limitations were determined and compared among the levels. Frequency of limitation in activities regarding social activity, housework, locomotion, mobility and self-care was compared among across the disability level. Results The GLFS-25 score was mathematically categorized into 7 levels. The number of activity limitations and the degrees of each activity limitation were significantly greater in high GLFS-25 levels than in low levels. Difficulties in mobility appeared in less severe level, difficulties in domestic and social life appeared in moderately severe level, and difficulties in self-care appeared in advanced level. Conclusions High GLFS-25 score represented high degree of disability on ADLs. Concordant increase of numbers of activity limitation and severity progression in activity limitation may contribute to progression of disability. Activity limitation may occur in the following order: sports activity, walking, transferring, and self-care.

Background: Healthy life expectancy (HLE) is used as one of the primary objectives of fundamental health promotion plans and social development plans. Activity limitation is used to calculate HLE, but little study has been done to identify determinants of activity limitation in order to extend HLE. The purpose of this study is to identify diseases and injuries that commonly lead to activity limitation to prioritize countermeasures against activity limitation. Methods: We used anonymous data from the 2007 “Comprehensive Survey of Living Conditions,” collected by the Ministry of Health, Labour and Welfare of Japan according to the Statistics Act, Article 36. We used logistic regression analyses and calculated odds ratios (ORs) after adjusting for age and sex. Limitation in daily activities was applied as the dependent variable, and each disease/injury was applied as an independent variable in this analysis. Furthermore, population attributable fractions (PAFs) were calculated. Results: The provided data included 98,789 subjects. We used data for 75,986 valid subjects aged 12 years or older. The following diseases showed high PAF: backache (PAF 13.27%, OR 3.88), arthropathia (PAF 7.61%, OR 4.82), eye and optical diseases (PAF 6.39%, OR 2.01), and depression and other mental diseases (PAF 5.70%, OR 11.55). PAFs of cerebrovascular diseases, hypertension, and diabetes were higher for males than for females; on the other hand, PAFs of orthopedic diseases were higher among females. Conclusions: Our results indicate that orthopedic diseases, ophthalmic diseases, and psychiatric diseases particularly affect activity limitation.