626 results on '"Acuña-Castroviejo, Darío"'
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2. Targeting NR1D1 in organ injury: challenges and prospects
3. The NLRP3 inflammasome: contributions to inflammation-related diseases
4. Intratumoral injection of melatonin enhances tumor regression in cell line-derived and patient-derived xenografts of head and neck cancer by increasing mitochondrial oxidative stress
5. Patient-derived tumor models in cancer research: Evaluation of the oncostatic effects of melatonin
6. Zebrafish as a Human Muscle Model for Studying Age-Dependent Sarcopenia and Frailty
7. Scientists Against War: A Plea to World Leaders for Better Governance
8. Inflamma-miRs Profile in Myelodysplastic Syndrome Patients.
9. Differences in the Interleukins profile in Inatentive-ADHD prepubertal children are probably related to comorbidities
10. Changes in Cortisol and in Oxidative/Nitrosative Stress Indicators after ADHD Treatment
11. Harbingers of hope: Scientists and the pursuit of world peace
12. Changes in Cortisol and in Oxidative/Nitrosative Stress Indicators after ADHD Treatment
13. From Chronodisruption to Sarcopenia: The Therapeutic Potential of Melatonin
14. Melatonin alleviates sepsis-induced heart injury through activating the Nrf2 pathway and inhibiting the NLRP3 inflammasome
15. The Relationship between Clock Genes, Sirtuin 1, and Mitochondrial Activity in Head and Neck Squamous Cell Cancer: Effects of Melatonin Treatment
16. iMS‐Bmal1−/− mice show evident signs of sarcopenia that are counteracted by exercise and melatonin therapies
17. Retinoid-related orphan nuclear receptor alpha (RORα)-deficient mice display morphological testicular defects
18. iMS‐Bmal1−/− mice show evident signs of sarcopenia that are counteracted by exercise and melatonin therapies.
19. Insights into the Role of Plasmatic and Exosomal microRNAs in Oxidative Stress-Related Metabolic Diseases
20. Chronodisruption and Loss of Melatonin Rhythm, Associated with Alterations in Daily Motor Activity and Mitochondrial Dynamics in Parkinsonian Zebrafish, Are Corrected by Melatonin Treatment
21. Alteration of Biological Rhythms in Diseases of the Central Dopaminergic System: Focus on Parkinson’s Disease
22. A phase II, single-center, double-blind, randomized placebo-controlled trial to explore the efficacy and safety of intravenous melatonin in patients with COVID-19 admitted to the intensive care unit (MelCOVID study): a structured summary of a study protocol for a randomized controlled trial
23. Daily Changes in the Expression of Clock Genes in Sepsis and Their Relation with Sepsis Outcome and Urinary Excretion of 6-Sulfatoximelatonin
24. Article Chronodisruption and Loss of Melatonin Rhythm, Associated with Alterations in Daily Motor Activity and Mitochondrial Dynamics in Parkinsonian Zebrafish, Are Corrected by Melatonin Treatment
25. Role of Melatonin in Cancer: Effect on Clock Genes
26. A phase II, single‐center, double‐blind, randomized placebo‐controlled trial to explore the efficacy and safety of intravenous melatonin in surgical patients with severe sepsis admitted to the intensive care unit
27. Melatonin in Mood Disorders and Agomelatine’s Antidepressant Efficacy
28. Melatonin and Pain: Therapeutic Applications
29. Melatonin in Parkinson’s Disease and Its Therapeutic Potential
30. Synthesis, structure and biological activity of 3(5)-trifluoromethyl-1H-pyrazoles derived from hemicurcuminoids
31. Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation
32. Melatonin enhances neural stem cell differentiation and engraftment by increasing mitochondrial function
33. Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis
34. Targeting NLRP3 (Nucleotide-Binding Domain, Leucine-Rich–Containing Family, Pyrin Domain–Containing-3) Inflammasome in Cardiovascular Disorders
35. Identification of mitochondrial deficits and melatonin targets in liver of septic mice by high-resolution respirometry
36. Deciphering clock genes as emerging targets against aging
37. Melatonin, clock genes and mitochondria in sepsis
38. Contribution of inducible and neuronal nitric oxide synthases to mitochondrial damage and melatonin rescue in LPS-treated mice
39. Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport
40. Role of c-miR-21, c-miR-126, Redox Status, and Inflammatory Conditions as Potential Predictors of Vascular Damage in T2DM Patients
41. Understanding the Mechanism of Action of Melatonin, Which Induces ROS Production in Cancer Cells
42. Identification of PIK3CG as a hub in septic myocardial injury using network pharmacology and weighted gene co‐expression network analysis
43. The Zebrafish, an Outstanding Model for Biomedical Research in the Field of Melatonin and Human Diseases
44. Age and Chronodisruption in Mouse Heart: Effect of the NLRP3 Inflammasome and Melatonin Therapy
45. A phase II, single‐center, double‐blind, randomized placebo‐controlled trial to explore the efficacy and safety of intravenous melatonin in surgical patients with severe sepsis admitted to the intensive care unit.
46. Synthesis of oxadiazoline and quinazolinone derivatives and their biological evaluation as nitric oxide synthase inhibitors
47. Salivary Melatonin Rhythm and Prostate Cancer: CAPLIFE Study
48. Synthesis and biological evaluation of 4,5-dihydro-1H-pyrazole derivatives as potential nNOS/iNOS selective inhibitors. Part 2: Influence of diverse substituents in both the phenyl moiety and the acyl group
49. Mitochondrial regulation by melatonin And its metabolites
50. CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome
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