462 results on '"Adelman, Karen"'
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2. RNA polymerase II pausing is essential during spermatogenesis for appropriate gene expression and completion of meiosis
3. The splicing factor CCAR1 regulates the Fanconi anemia/BRCA pathway
4. Global identification of SWI/SNF targets reveals compensation by EP400
5. U1 snRNP increases RNA Pol II elongation rate to enable synthesis of long genes
6. Integrator is a global promoter-proximal termination complex
7. PGC-1α senses the CBC of pre-mRNA to dictate the fate of promoter-proximally paused RNAPII
8. The Histone Deacetylase SIRT6 Restrains Transcription Elongation via Promoter-Proximal Pausing.
9. Integrator endonuclease drives promoter-proximal termination at all RNA polymerase II-transcribed loci
10. Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells
11. Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq
12. Screening thousands of transcribed coding and non-coding regions reveals sequence determinants of RNA polymerase II elongation potential
13. Rixosomal RNA degradation contributes to silencing of Polycomb target genes
14. Overcoming IMiD resistance in T-cell lymphomas through potent degradation of ZFP91 and IKZF1
15. Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis
16. Negative elongation factor regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation
17. Co-transcriptional splicing regulates 3′ end cleavage during mammalian erythropoiesis
18. Integrator Recruits Protein Phosphatase 2A to Prevent Pause Release and Facilitate Transcription Termination
19. RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells
20. The Integrator Complex Attenuates Promoter-Proximal Transcription at Protein-Coding Genes
21. PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression
22. Decoding the Epigenetics and Chromatin Loop Dynamics of Androgen Receptor-Mediated Transcription
23. Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML
24. Nascent transcription as a predictor and driver of histone modifications
25. Emerging Roles of Non-Coding RNA Transcription
26. Acetylation of RNA Polymerase II Regulates Growth-Factor-Induced Gene Transcription in Mammalian Cells
27. Probing TBP Interactions in Transcription Initiation and Reinitiation with RNA Aptamers That Act in Distinct Modes
28. Decoding the Epigenetics and Chromatin Loop Dynamics of Androgen Receptor-Mediated Transcription
29. Intragenic Enhancers Attenuate Host Gene Expression
30. Single Molecule Analysis of RNA Polymerase Elongation Reveals Uniform Kinetic Behavior
31. Solution Structure and Stability of the Anti-Sigma Factor AsiA: Implications for Novel Functions
32. Herpes Simplex Virus DNA Packaging Sequences Adopt Novel Structures That are Specifically Recognized by a Component of the Cleavage and Packaging Machinery
33. Stimulation of Bacteriophage T4 Middle Transcription by the T4 Proteins MotA and AsiA occurs at two Distinct Steps in the Transcription Cycle
34. TP63 fusions drive multicomplex enhancer rewiring, lymphomagenesis, and EZH2 dependence
35. NF-Y controls fidelity of transcription initiation at gene promoters through maintenance of the nucleosome-depleted region
36. RNA polymerase II pausing is essential during spermatogenesis for appropriate gene expression and completion of meiosis
37. Oncogenic CDK13 mutations impede nuclear RNA surveillance
38. Abstract 5755: TP63 fusions drive enhancer rewiring, lymphomagenesis, and dependence on EZH2
39. Bidirectional Transcription Arises from Two Distinct Hubs of Transcription Factor Binding and Active Chromatin
40. Pausing of RNA Polymerase II Regulates Mammalian Developmental Potential through Control of Signaling Networks
41. Global identification of direct SWI/SNF targets reveals compensation by EP400
42. Global Identification of Direct SWI/SNF Targets Reveals Compensation by EP400
43. Preparing the First Responders: Building the Inflammatory Transcriptome from the Ground Up
44. Abstract A020: Histone modification by Kmt2c and Kmt2d regulate metastasis in triple-negative breast cancer in vivo
45. Co-depletion of NIPBL and WAPL balance cohesin activity to correct gene misexpression
46. Splicing Modulators Impair DNA Damage Response and Induce Killing of Cohesin-Mutant MDS/AML
47. TP63 Fusions Drive Enhancer Rewiring, Lymphomagenesis, and Dependence on EZH2
48. Stable Pausing by RNA Polymerase II Provides an Opportunity to Target and Integrate Regulatory Signals
49. Glucocorticoid receptor represses proinflammatory genes at distinct steps of the transcription cycle
50. Defining the Status of RNA Polymerase at Promoters
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