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1. The 2024 international survey of platelet products and practice

Author

Tani, Yoshihiko, Kwon, So-Yong, Chiueh, Tzong-Shi, Sarantuya, Badmaarag Ruby, Kam, Wooi Seong, Ang, Ai Leen, Bin Kambali, Mohd Muhaimin, Nguyen, Quang The, Aditya, Robby Nur, Kupatawintu, Pawinee, Roy, Asitava Deb, Desai, Priti, Shivaram, Chandrashekar, Saeed, Fauzia, Kabir, S.M. Humauyn, Daly, James, Charlewood, Richard, Auvinen, Marja-Kaisa, Nordström, Magnus, Bengtsson, Jesper, Akkök, Cigdem Akalin, Danilova, Elena, Ernstsen, Siw Leiknes, Köylijärvi, Marjut, Soerensen, Betina, Hansen, Morten Bagge, Bruun, Mie Topholm, Wagner, Thomas, El Dusouqui, Soraya Amar, Estcourt, Lise, Doyle, Barry, Deneys, Véronique, Antoniewicz-Papis, Jolanta, Lachert, Elżbieta, Revelli, Nicoletta, Coluccio, Elena Beatrice, Teofili, Luciana, Matteocci, Antonella, Pierelli, Luca, Pirenne, France, Nogués, Eva Alonso, Koutsogianni, Panagiota, Zervou, Eleftheria, Stanić, Hana Safić, Đozo, Aida, Gökçebay, Dilek Gürlek, Townsend, Mary, Blumberg, Neil, Zeller, Michelle, Langhi, Dante, Gonzalez, Carlos Alberto, Kabambi, Kasandji Freddy, Boateng, Lilian Antwi, Gorgy, George S, Ohto, Hitoshi, Flegel, Willy A., van der Meer, Pieter F., Ngoma, Alain M., Nollet, Kenneth E., Choudhury, Nabajyoti, and Legler, Tobias J.

Published
2025
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2. Histodynamics of Natural Killer Cells from a Healthy Donor Exposed to Exosomes from the Blood of Hepatocellular Carcinoma Patients.

Author

Asrinda, Indria, Antarianto, Radiana Dhewayani, Jusuf, Ahmad Aulia, Ahani, Ardhi Rahman, Jasirwan, Chyntia Olivia Maurine, Ritchie, Ni Ken, Aditya, Robby Nur, and Irawan, Cosphiadi

Subjects
ENDOCYTOSIS, FLOW cytometry, KILLER cells, RESEARCH funding, CELL physiology, FLUORESCENT antibody technique, CELL culture, GENE expression, STAINS & staining (Microscopy), DATA analysis software, HEPATOCELLULAR carcinoma, EXOSOMES, PHENOTYPES, CELL receptors
Abstract

Background: Hepatocellular carcinoma (HCC) is the leading form of liver cancer and the second leading cause of cancer-related deaths globally. Exosomes in the HCC microenvironment can induce significant changes in natural killer (NK) cells during endocytosis. The present study aimed to distinguish exosomes in the blood of HCC patients, analyze changes in NK cell phenotype, and evaluate peroxidase and toluidine blue staining as alternative methods for observing the changes. Methods: NK cells were collected from healthy donors, and exosomes were extracted from the blood of HCC patients. The exosomes were characterized in accordance with MISEV 2018 guidelines, and NK cells were incubated with HCC-derived exosomes. NK cell phenotype changes were assessed using immunofluorescence, toluidine blue staining, and peroxidase staining. Results: The identified exosomes measured 34.7 nm, had a charge of -4.33 mV, and were positive for CD81+. Changes in NK cell receptor expression following exposure to HCC exosomes were not significant (p > 0.05). Immunofluorescence confirmed exosome endocytosis by NK cells, toluidine blue staining revealed negative metachromasia and peroxidase staining indicated morphological NK cell changes. Conclusions: This study demonstrates that peroxidase and toluidine blue staining are effective for observing exosome endocytosis in NK cells, enhancing our understanding of HCC exosome-NK cell interactions and beneficial in developing future therapeutic strategies targeting the HCC microenvironment. [ABSTRACT FROM AUTHOR]

Published
2024
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4. International Forum on Blood Donation in Individuals with Current, Past or Germline Predisposition to Malignancy: Summary

Author

Baggio, Diva, primary, Fox, Lucy C., additional, Wood, Erica M., additional, Aditya, Robby Nur, additional, Goldman, Mindy, additional, van den Berg, Karin, additional, Kayser, Sabine, additional, Wuchter, Patrick, additional, Namba, Noriko, additional, Tsuno, Nelson H., additional, Makino, Shigeyoshi, additional, Lee, Cheuk Kwong, additional, Akhtar, Naim, additional, Shah, Farrukh, additional, Miflin, Gail, additional, Prati, Daniele, additional, La Raja, Massimo, additional, La Rocca, Ursula, additional, Richard, Pascale, additional, Tiberghien, Pierre, additional, Harley, Robert J., additional, Raouf, May Y., additional, Sharma, Ranjita, additional, Kaur, Suminder, additional, Bruijns, Sanne, additional, Prakke‐Weekamp, Henriette, additional, and Dunbar, Nancy, additional

Published
2023
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5. International Forum on Blood Donation in Individuals with Current, Past or Germline Predisposition to Malignancy: Responses

Author

Baggio, Diva, primary, Fox, Lucy C., additional, Wood, Erica M., additional, Aditya, Robby Nur, additional, Goldman, Mindy, additional, van den Berg, Karin, additional, Kayser, Sabine, additional, Wuchter, Patrick, additional, Namba, Noriko, additional, Tsuno, Nelson H., additional, Makino, Shigeyoshi, additional, Lee, Cheuk Kwong, additional, Akhtar, Naim, additional, Shah, Farrukh, additional, Miflin, Gail, additional, Prati, Daniele, additional, La Raja, Massimo, additional, Rocca, Ursula La, additional, Richard, Pascale, additional, Tiberghien, Pierre, additional, Harley, Robert J., additional, Raouf, May Y., additional, Sharma, Ranjita, additional, Kaur, Suminder, additional, Bruijns, Sanne, additional, Prakke‐Weekamp, Henriette, additional, and Dunbar, Nancy, additional

Published
2023
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6. Bioreactors for Hematopoietic Stem Cell and Progenitor Expansion.

Author

Aditya, Robby Nur and Pawitan, Jeanne Adiwinata

Abstract

Objective: To describe the use of bioreactors for hematopoeitic stem cell and progenitor cell culture and comparing the various bioreactors to know which one is the best. Materials and Method: We conducted a data search on PubMed in December 18, 2021 and January 18, 2022. We used "Bioreactor" AND "Hematopoietic stem cell" OR "progenitor" as keywords. Data collection procedure: search results were filtered and selected so that only articles, which contained data about the type of bioreactor, mechanism of bioreactor, and cell source of HSC and progenitors, were used. Result and Discussion: The search yielded nine articles that were used to compose this narrative review. There are two main bioreactor classification, perfusion and stirred tank bioreactor. There are various models, which can be adapted easily according to research needs, such as microfluidic, hollow fibre, continuous perfusion and micro-cavity array bioreactors. Conclusion: Comparison between those bioreactors showed that perfusion bioreactor is more advantageous and widely used for research purposes that are related to HSCs and progenitors. This fact is due to the possibility of a simpler type and more benefits than stirred types. [ABSTRACT FROM AUTHOR]

Published
2023

8. International Forum on the Collection and Use of COVID‐19 Convalescent Plasma: Protocols, Challenges and Lessons Learned: Summary

Author

Al-Riyami, Arwa, Burnouf, Thierry, Yazer, Mark, Triulzi, Darrell, Kumaş, Levent Tufan, Sağdur, Levent, Pelit, Nil Banu, Bazin, Renée, Hindawi, Salwa, Badawi, Maha, Patidar, Gopal, Pandey, Hem Chandra, Chaurasia, Rahul, Fachini, Roberta Maria, Scuracchio, Patrícia, Wendel, Silvano, Ang, Ai Leen, Ong, Kiat Hoe, Young, Pampee, Ihalainen, Jarkko, Vierikko, Antti, Qiu, Yan, Yang, Ru, Xu, Hua, Rahimi-Levene, Naomi, Shinar, Eilat, Izak, Marina, Gonzalez, Carlos Alberto, Ferrari, David Martin, Cini, Paula Verónica, Aditya, Robby Nur, Sharma, Ratti Ram, Sachdev, Suchet, Hans, Rekha, Lamba, Divjot Singh, Nissen-Meyer, Lise Sofie H, Devine, Dana, Lee, Cheuk Kwong, Leung, Jennifer Nga-Sze, Hung, Ivan Fan Ngai, Tiberghien, Pierre, Gallian, Pierre, Morel, Pascal, Al Maamari, Khuloud, Al-Hinai, Zaid, Vrielink, Hans, So-Osman, Cynthia, De Angelis, Vincenzo, Berti, Pierluigi, Ostuni, Angelo, Marano, Giuseppe, Nevessignsky, Michel Toungouz, El Ekiaby, Magdy, Daly, James, Hoad, Veronica, Kim, Sinyoung, van den Berg, Karin, Vermeulen, Marion, Glatt, Tanya Nadia, Schäfer, Richard, Reik, Rita, Gammon, Richard, Lopez, Melissa, Estcourt, Lise, MacLennan, Sheila, Roberts, David, Louw, Vernon, Dunbar, Nancy, Al‐Riyami, Arwa, Rahimi‐Levene, Naomi, Nissen‐Meyer, Lise Sofie H., Leung, Jennifer Nga‐Sze, Al‐Hinai, Zaid, So‐Osman, Cynthia, Berg, Karin, and Institut Hospitalier Universitaire Méditerranée Infection (IHU Marseille)

Subjects
0303 health sciences, 2019-20 coronavirus outbreak, Convalescent plasma, Coronavirus disease 2019 (COVID-19), business.industry, SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), [SDV]Life Sciences [q-bio], Immunization, Passive, COVID-19, Hematology, General Medicine, 030204 cardiovascular system & hematology, Virology, 03 medical and health sciences, 0302 clinical medicine, Medicine, Humans, business, Coronavirus Infections, International Forum, COVID-19 Serotherapy, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology
Abstract

International audience

Published
2021
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9. International Forum on the Collection and Use of COVID‐19 Convalescent Plasma: Responses

Author

Al‐Riyami, Arwa Z., primary, Burnouf, Thierry, additional, Yazer, Mark, additional, Triulzi, Darrell, additional, Kumaş, Levent Tufan, additional, Sağdur, Levent, additional, Pelit, Nil Banu, additional, Bazin, Renée, additional, Hindawi, Salwa I., additional, Badawi, Maha A., additional, Patidar, Gopal K., additional, Pandey, Hem Chandra, additional, Chaurasia, Rahul, additional, Fachini, Roberta Maria, additional, Scuracchio, Patrícia, additional, Wendel, Silvano, additional, Ang, Ai Leen, additional, Ong, Kiat Hoe, additional, Young, Pampee, additional, Ihalainen, Jarkko, additional, Vierikko, Antti, additional, Qiu, Yan, additional, Yang, Ru, additional, Xu, Hua, additional, Rahimi‐Levene, Naomi, additional, Shinar, Eilat, additional, Izak, Marina, additional, Gonzalez, Carlos Alberto, additional, Ferrari, David Martin, additional, Cini, Paula Verónica, additional, Aditya, Robby Nur, additional, Sharma, Ratti Ram, additional, Sachdev, Suchet, additional, Hans, Rekha, additional, Lamba, Divjot Singh, additional, Nissen‐Meyer, Lise Sofie H., additional, Devine, Dana V., additional, Lee, Cheuk Kwong, additional, Leung, Jennifer Nga‐Sze, additional, Hung, Ivan Fan Ngai, additional, Tiberghien, Pierre, additional, Gallian, Pierre, additional, Morel, Pascal, additional, Al Maamari, Khuloud, additional, Al‐Hinai, Zaid, additional, Vrielink, Hans, additional, So‐Osman, Cynthia, additional, De Angelis, Vincenzo, additional, Berti, Pierluigi, additional, Ostuni, Angelo, additional, Marano, Giuseppe, additional, Nevessignsky, Michel Toungouz, additional, El Ekiaby, Magdy, additional, Daly, James, additional, Hoad, Veronica, additional, Kim, Sinyoung, additional, Berg, Karin, additional, Vermeulen, Marion, additional, Glatt, Tanya Nadia, additional, Schäfer, Richard, additional, Reik, Rita, additional, Gammon, Richard, additional, Lopez, Melissa, additional, Estcourt, Lise, additional, MacLennan, Sheila, additional, Roberts, David, additional, Louw, Vernon, additional, and Dunbar, Nancy, additional

Published
2021
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10. International Forum on the Collection and Use of COVID-19 Convalescent Plasma: Protocols, Challenges and Lessons Learned: Summary.

Author

Al-Riyami AZ, Burnouf T, Yazer M, Triulzi D, Kumaş LT, Sağdur L, Pelit NB, Bazin R, Hindawi SI, Badawi MA, Patidar GK, Pandey HC, Chaurasia R, Fachini RM, Scuracchio P, Wendel S, Ang AL, Ong KH, Young P, Ihalainen J, Vierikko A, Qiu Y, Yang R, Xu H, Rahimi-Levene N, Shinar E, Izak M, Gonzalez CA, Ferrari DM, Cini PV, Aditya RN, Sharma RR, Sachdev S, Hans R, Lamba DS, Nissen-Meyer LSH, Devine DV, Lee CK, Leung JN, Hung IFN, Tiberghien P, Gallian P, Morel P, Al Maamari K, Al-Hinai Z, Vrielink H, So-Osman C, De Angelis V, Berti P, Ostuni A, Marano G, Nevessignsky MT, El Ekiaby M, Daly J, Hoad V, Kim S, van den Berg K, Vermeulen M, Glatt TN, Schäfer R, Reik R, Gammon R, Lopez M, Estcourt L, MacLennan S, Roberts D, Louw V, and Dunbar N

Subjects
Humans, Immunization, Passive, SARS-CoV-2, COVID-19 Serotherapy, COVID-19 therapy, Coronavirus Infections
Published
2021
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