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Intravesical ectopic pregnancy is a very rare condition. Unlike traditional ectopic pregnancies, patients generally present with hematuria. Our case presented with abdominal pain and urinary bleeding. Abdominal tenderness was observed on physical examination. The ß-HCG was measured as 10033 IU / ml. In ultrasonography, an appearance compatible with a vesicouterine fistula tract and an ectopic gestational sac in the bladder were observed. In cystoscopy, a mass compatible with a fistula tract ostium and ectopic gestational sac was observed at the junction of the right side of the bladder and the posterior wall. The observed structure was resected and cauterized to achieve hemostasis. No complications were observed during the follow-up, and the patient was discharged. Ectopic pregnancy should be one of the differential diagnoses of patients with a history of pelvic surgery who present with complaints of menstrual delay and hematuria. Keywords: vesical pregnancy, vesicouterine fistula, hematuria

Objective: The purpose of this study is to evaluate the clinical findings, tumor markers, surgical treatment ap­proaches and final pathological results of the dermoid cyst subjects treated at our hospital. Methods: The study was planned retrospectively. 114 subjects with dermoid cyst were included from our hos­pitals electronic log system. Along with the demographic data’s, pre-operative clinical findings, tumor sizes, ul­trasonographic characteristics, tumor marker results, surgical treatment method (laparotomy-laparoscopy), administered surgical treatment procedure (cystectomy, oopherectomy, salpingo-oopherectomy, total abdominal hysterectomy-salpingo-oopherectomy) and pathology re­sults were recorded from the patient files. Results: Mean age of the patients was 33.59±12.79 years (11-70). Abdominal pain was observed in 32 patients (%28.07) as the most common complaint during hospi­tal admission. 70 patients (%38.59) were determined in­cidentally. Average cyst size was 47.70±48.49 cm2 dur­ing the ultrasonographic examination. Ca 125 level was higher than normal limits in only 12 (%10.52) patients and Ca 19-9 level was higher in only 29 (%25.43) of patients. The most common final histopathological diagnosis was dermoid cyst in 103 (%90.40) patients. Other histopatho­logical diagnoses were immature teratoma, squamous cell carcinoma and serous carcinoma. Conclusion: Ovarian dermoid cysts are usually benign neoplasms and rarely show malign transformations. Tu­mor markers are not fairly enough to make discrimina­tions. However especially in older patients treatment should be done cautiously due to the raised risk of ma­lignity.

Objective: The aim of this study is evaluating the protective activity of N-acetyl cysteine and resveratrol treatment against ischemia - reperfusion damage created experimentally in rat ovaries. Methods: 42 female Wistar rats were used in our study. Rats were separated randomly into six groups consisting of seven rats as sham, torsion, torsion- detorsion, torsion-detorsion+saline, torsion-detorsion+resveretrol (20 mg/kg) and torsion- detorsion+N-acetyl cysteine (150 mg/kg). Except Sham, ovarian torsion procedure was implemented to all other groups for 2 hours. Detorsion procedure was implemented to other groups for 2 hours, except the torsion group. Medications were given through intraperitoneal way half an hour before the detorsion procedure in saline (two milliliter), resveratrol (20 mg/kg) and N-acetyl cysteine (150 mg/kg) groups. Then, 2 ml of blood samples were drawn for markers of oxidative stress and tumour necrosis factor-alpha (TNF-α) work and the ovaries, which were torsioned for the histologic examination, were ex­tracted from all rats. Edema, congestion, hemorrhage, leuko­cyte infiltration and degeneration of follicles were evaluated by histopathological examination. Results: According to histopathologic damage scores, the least damage was seen in sham group and the most damage was seen T-DT group (1.00±0.81 vs. 11.00±1.15, respectively; p

Amaç: Gestasyonel diyabet taramasında kullanılan 50 g glukoz yükleme testinin gerekli olup olmadığını araştırmak. Gereç ve Yöntemler: Bu retrospektif çalışmada Özel OSM Hastanesi Kadın Hastalıkları ve Doğum polikliniğine antenatal takip için başvurmuş olan 143 gebe kadına dair kayıtlar incelendi.Gestasyonel diyabet taraması uygulanan tüm gebeler 24–28. gestasyonel haftalar arasında idi. Hastalar iki gruba ayrıldı. Birinci gruba (n=76) 50 g glukoz, ikinci gruba (n=67) 75 g glukozyükleme testi yapılmıştı. Birinci grupta test sonucu pozitif olan gebelere 100 g oral glukoz yükleme testi yapılmıştı. Her iki yükleme testi ve 100 g oral glukoz yükleme testi, Amerikan Diyabet Birliği’nin önerdiği şekilde uygulanmıştı. Bulgular: 50 g glukoz yükleme testi yapılan birinci gruptaki hastaların yaş ortalaması 27,4 ± 5,5 (dağılım 18-42) olup 23’ünde test pozitif sonuçlanmıştı. Bu hastaların da 13’ünde (%17) 100 g oral glukoz yükleme testi pozitif sonuçlanmıştı. 75 g glukoz yükleme testi yapılan yapılan ikinci gruptaki hastaların yaş ortalaması 26,9 ± 5,9 (dağılım 17- 43) olup 14’ünde (%21) test pozitifsonuçlanmıştı. İkinci grupta daha sık test pozitifliği saptanmasına rağmen, iki grup arasında istatistiksel fark bulunmadı (p>0,05).Tartışma ve Sonuç: Her iki test ile benzer sıklıkta gestasyonel diyabet tanısı alan hasta saptanmıştır. Bu nedenle iki aşamalı olan ve buna bağlı olarak daha fazla glukoz alınmasına neden olan 50 g glukoz yükleme testinin gerekli olmayabileceği sonucuna varılabilir.

Objective: The aim of this study was to investigate therole of pelvic magnetic resonance imaging (MRI) in makingthe correct diagnosis of massive ovarian edema(MOE) and ovarian torsion (OT).Methods: Contrast-enhanced (CE) pelvic MRI and diffusion-weighted imaging (DWI) was performed in 4 patientsadmitted to hospital with lower abdominal pain and hadpre-diagnosis of OT and MOE with B-mode ultrasoundand Doppler ultrasoundResults: Doppler ultrasound examination of ovaries inthree patients with OT did not reveal arterial or venousflow. In the patients with MOE, monophasic arterial flowwith prolonged acceleration was detected. Venous flowwas not detected. Left ovary size of the patient with MOEincreased. Heterogeneous low-intensity on T1W imagesand heterogeneous high intensity on T2A-weighted imageswere observed. CE fat-saturated T1WI revealed partialparenchymal enhancement. Size of the ovaries increasedin two patients with OT. Homogeneous low and high intensitywere observed respectively on T1WI and T2WI.There was no parenchymal enhancement on CE fat-saturatedT1WI. Size of the ovaries increased in other patientwith OT. Reduction and increment of intensity reflectingthe hemorrhagic infarction were observed respectively onT2WI and T1WI, which became evident to the periphery.DWI of ovarian tissue in patients with ovarian torsion revealeddiffusion limitations reflecting the infarction.Conclusions: OT can be differentiated correctly fromMOE with the CE pelvic MRI findings of patients. Pre-operativelyinformation determined from DWI can help guideclinicians to decide for correct type of surgery. J Clin ExpInvest 2013; 4 (1): 95-100Key words: Massive ovarian edema, ovarian torsion,magnetic resonance imaging

This study compared the placental expression of the matrix metalloproteinase-2 (MMP-2) enzyme, which is thought to play a key role in the penetration of trophoblastic cells, in third-trimester placenta percreta (PP) patients with that of women with normal pregnancies.Twenty-five pregnant subjects who underwent cesarean section due to PP and 25 term pregnant subjects who underwent cesarean section for obstetric reasons were included in the study. Demographic data, pathology reports, and histopathological samples were examined. Blocks containing samples of placenta underwent immunohistochemical analysis using the MMP-2 antibody. Immunohistochemical expression of placental samples obtained from both groups was examined and compared.There were no statistically significant differences in the demographic data (P 0.05). With regard to immunohistochemistry, cytoplasmic staining of trophoblastic cells was considered immunohistochemically positive. In the PP tissue samples, positive MMP-2 staining was detected as follows: 0 immunoreactivity, one patient (4%); 1(+), six patients (24%); 2(+), seven patients (28%); and 3(+), 11 patients (44%). In the term pregnant placental tissue samples, positive MMP-2 staining was detected in five patients (20%) at 0 immunoreactivity, 12 (48%) at 1(+) immunoreactivity, five (20%) at 2(+) immunoreactivity, and three patients (12%) at 3(+) immunoreactivity. Immunohistochemical expression was significantly different between the PP and normal term pregnancy placental tissues (P = 0.02).The stronger expression of the MMP-2 enzyme in the PP as compared to the normal placental tissue suggests that this enzyme may be an effective mediator in the pathogenesis of PP.