1. Myxoinflammatory Fibroblastic Sarcoma
- Author
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Afranio dos Reis Teixeira Neto, Rajendra Kumar, and Robert A. Lefkowitz
- Subjects
Adult ,Male ,medicine.medical_specialty ,Soft Tissue Neoplasm ,Fibrosarcoma ,Soft Tissue Neoplasms ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Aged ,Retrospective Studies ,medicine.diagnostic_test ,business.industry ,Soft tissue sarcoma ,Soft tissue ,Myxoma ,Magnetic resonance imaging ,Middle Aged ,medicine.disease ,Magnetic Resonance Imaging ,United States ,Treatment Outcome ,Pigmented villonodular synovitis ,030220 oncology & carcinogenesis ,Female ,Histopathology ,Radiology ,business - Abstract
Objective This retrospective study was undertaken to highlight clinical and magnetic resonance imaging features of myxoinflammatory fibroblastic sarcoma. Methods The clinical records of 29 patients (14 men and 15 women) were analyzed. Results The soft tissue tumors involved hand, wrist, foot and ankle in 21 patients, more proximal extremities in 7 patients, and neck in 1 patient. The tumors were subcutaneous in 11 patients, and intramuscular in 15 patients. On magnetic resonance imaging, these tumors had nonspecific features suggestive of benign and malignant lesions. An unusual tumor in hand indicated infection, whereas an intraarticular knee tumor mimicked pigmented villonodular synovitis. All tumors were surgically resected. Conclusions Myxoinflammatory fibroblastic sarcoma, a rare low-grade subcutaneous soft tissue tumor of distal extremities with high local recurrence after resection can mimic several benign and malignant lesions on histopathology and imaging. Rarely, it can arise in muscles and tendons, occur in nonacral sites, be aggressive, and even metastasize. In most cases, surgical resection with wide margins can be curative with low local recurrence.
- Published
- 2017
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