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3. Changes in Dietary Behaviours During the COVID-19 Outbreak Confinement in the Adult Population (COVIDiet_Int) (COVIDiet_Int)

Author

Agricultural University of Athens, University of Zagreb, University of Belgrade, Institute of Technology, Sligo, University of Sarajevo, Lithuanian University of Health Sciences, Jozef Stefan Institute, University of Southern Denmark, Institut Za Javno Zdeavlje, University of Skopje, Poznan University of Life Sciences, Bezmialem Vakif University, Centro Hospitalar e Universitário de Coimbra, E.P.E., Kuwait University, Universidad Nacional de Colombia, Manay Rachna International institute of Research and Studies, and Celia Rodríguez Pérez, Associate Professor in Nutrition and Food Science

Published
2022

8. SWINOSTICS – Swine diseases field diagnostics toolbox. General presentation at X International Symposium of Mediterranean Pig (X-PIGMED-2019)

Author

Cy.R.I.C Cyprus Research And Innovation Center Ltd, Agricultural University Of Athens, Kontor 46 Di Bonasso Matteo Sas, Ricerche, Consiglio Nazionale Delle, Iss Biosense Srl, Lumensia Sensors Sl, Universitat Politecnica De Valencia, National Veterinary Research Institute, University Of Veterinary Medicine, and University of Florence, Department Of Agrifood Production And Environmental Sciences (DAGRI)

Abstract

UNIFIorganizedthe X International Symposium of Mediterranean Pig (X-PIGMED-2019) that was held in Florence, at Camera di Commercio building, fromOctober 16th-19th, 2019. The aim of the event was to promote valuable scientific contents and knowledge exchange, combining the latest developments with the traditional aspects of pig production. At the symposium were present stakeholders, Universities and Scientific Institutions working on pig production science at european and international level. The Event consisted of Scientific Sessions, including Main Lectures, Oral and Poster Sessions. Within Poster Session UNIFI presented a poster "Swine disease diagnostic toolbox", in order to make a general presentation of SWINOSTICS project and objectives. &nbsp

Published
2019
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9. SWINOSTICS poster

Author

Cy.R.I.C Cyprus Research and Innovation Center Ltd, Cyprus, Agricultural University Of Athens , Greece, Kontor 46 Di Bonasso Matteo Sas, Italy, Consiglio Nazionale Delle Ricerche, Italy, Iss Biosense Srl, Italy, Lumensia Sensors Sl, Spain, Universitat Politecnica De Valencia, Spain, National Veterinary Research Institute, Poland, University Of Veterinary Medicine, Hungary, and University of Florence, Department Of Agrifood Production And Environmental Sciences (DAGRI), Italy

Subjects
ComputingMilieux_THECOMPUTINGPROFESSION, ComputerApplications_GENERAL, TheoryofComputation_GENERAL, GeneralLiterature_MISCELLANEOUS
Abstract

SWINOSTICS was presented in the International Symposium of the Mediterranean Pig in Florence, Italy. This poster was used at the Symposium&nbsp

Published
2019
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10. Cross-European initial survey on the use of mathematical models in food industry

Author

Photis Papademas, Kamal Kansou, Alberto Tonda, Aleksandra Nikolić, Nickolas G. Kavallieratos, Ilija Djekic, Rallou Thomopoulos, Igor Tomasevic, Alen Mujčinović, Alexandrina Sirbu, Aberham Hailu Feyissa, Heiko Briesen, Alexandru Mihnea Moisescu, Anet Režek Jambrak, Urška Vrabič Brodnjak, Cristina L. M. Silva, Christos G. Athanassiou, Maria N. Charalambides, Department of Food Safety and Quality Management [Belgrade], Faculty of Agriculture [Belgrade], University of Belgrade [Belgrade]-University of Belgrade [Belgrade], Faculty of Agriculture and Food Sciences [Sarajevo], UNIVERZITET U SARAJEVU, Faculty of Food Technology & Biotechnology [Zagreb], University of Zagreb, Department of Agricultural Sciences, Biotechnology and Food Science [Limassol], Cyprus University of Technology, National Food Institute [Lyngby] (Forside), Unité de recherche sur les Biopolymères, Interactions Assemblages (BIA), Institut National de la Recherche Agronomique (INRA), Ingénierie des Agro-polymères et Technologies Émergentes (UMR IATE), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-Université Montpellier 2 - Sciences et Techniques (UM2)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Université de Montpellier (UM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Graphs for Inferences on Knowledge (GRAPHIK), Laboratoire d'Informatique de Robotique et de Microélectronique de Montpellier (LIRMM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Inria Sophia Antipolis - Méditerranée (CRISAM), Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria), Chair Process Systems Engineering [Freising], Technische Universität München [München] (TUM), Faculty of Crop Science [Athens], Agricultural University of Athens, Department of Agriculture Crop Production and Rural Environment [Volos], University of Thessaly [Volos] (UTH), Escola Superior de Biotecnologia [Porto], Universidade Católica Portuguesa [Porto], Constantin Brancoveanu University [Râmnicu Vâlcea], University Politehnica of Bucharest [Romania] (UPB), Department of Animal Origin Products Technology [Belgrade], Faculty of Natural Sciences and Engineering [Ljubljana], University of Ljubljana, Department of Chemical Engineering [London], Imperial College London, Génie et Microbiologie des Procédés Alimentaires (GMPA), Institut National de la Recherche Agronomique (INRA)-AgroParisTech, The authors would like to acknowledge the networking support by COST Action CA15118 (Mathematical and Computer Science Methods for Food Science and Industry - FoodMC) as well the help in conducting the survey provided by Prof. Dr Serafim Bakalis (Nottingham University), Dr. Efstathios Kaliviotis (Cyprus University of Technology), Mirza Uzunović (University of Sarajevo) and Erifili P. Nika (Agricultural University of Athens)., UNIVERSITY OF SARAJEVO - UNIVERZITET U SARAJEVU, Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM), European Project: 605414,EC:FP7:TPT,FP7-AAT-2013-RTD-1,CAPPADOCIA(2013), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Inria Sophia Antipolis - Méditerranée (CRISAM), Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Université Montpellier 2 - Sciences et Techniques (UM2)-Université de Montpellier (UM)-Institut National de la Recherche Agronomique (INRA), and Veritati - Repositório Institucional da Universidade Católica Portuguesa

Subjects
Micro level, Relation (database), Food industry, Knowledge in modellling, Context (language use), 03 medical and health sciences, 0404 agricultural biotechnology, 0302 clinical medicine, [SDV.IDA]Life Sciences [q-bio]/Food engineering, Lack of knowledge, Industrial organization, 2. Zero hunger, Mathematical models, Usage of models, Mathematical model, business.industry, 04 agricultural and veterinary sciences, Limiting, 040401 food science, ddc, [STAT]Statistics [stat], Food sector, 030221 ophthalmology & optometry, Business, Knowledge in modelling, 0908 Food Sciences, Food Science
Abstract

International audience; Mathematical modelling plays an important role in food engineering having various mathematical models tailored for different food topics. However, mathematical models are followed by limited information on their application in food companies. This paper aims to discuss the extent and the conditions surrounding the usage of mathematical models in the context of European food and drinks industry. It investigates the knowledge, nature and current use of modelling approaches in relation to the industry main characteristics. A total of 203 food companies from 12 European countries were included in this research.Results reveal that the country where the company operates, and size of the company, are more important predictors on the usage of mathematical models followed by the type of food sector. The more developed countries are positioned at the higher level of knowledge and use of available models. Similar pattern was observed at the micro level showing that small or medium sized companies exhibit lack of knowledge, resources and limiting usage of models.

Published
2019
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11. Physiological significance of pedospheric nitric oxide for root growth, development and organismic interactions

Author

Robert Hänsch, Bin Hu, Laurent Philippot, Ming Ma, David Wendehenne, Emmanouil Flemetakis, Heinz Rennenberg, Center of Molecular Ecophysiology ((CMEP)), College of Resources and Environment, Southwest University [Chongqing]-Southwest University [Chongqing], Agroécologie [Dijon], Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institute for Plant Biology, Technische Universität Braunschweig = Technical University of Braunschweig [Braunschweig], Laboratory of Molecular Biology, Department of Biotechnology, Agricultural University of Athens-Agricultural University of Athens, and Southwest University - China

Subjects
0106 biological sciences, 0301 basic medicine, Root growth, soil NO production and consumption, Physiological significance, Physiology, Plant Development, Plant Science, Biology, Plant Roots, 01 natural sciences, Nitric oxide, 03 medical and health sciences, chemistry.chemical_compound, Nutrient, environmental stress signalling, nitric oxide, Botany, [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, Lateral root formation, Plant Physiological Phenomena, Abiotic component, Rhizosphere, Atmosphere, Plants, 15. Life on land, rhizospheric NO homeostasis, root growth and development, 030104 developmental biology, chemistry, organismic interactions, Nitrogen fixation, 010606 plant biology & botany
Abstract

International audience; Nitric oxide (NO) is essential for plant growth and development, as well as interactions with abiotic and biotic environments. Its importance for multiple functions in plants means that tight regulation of NO concentrations is required. This is of particular significance in roots, where NO signalling is involved in processes, such as root growth, lateral root formation, nutrient acquisition, heavy metal homeostasis, symbiotic nitrogen fixation and root-mycorrhizal fungi interactions. The NO signal can also be produced in high levels by microbial processes in the rhizosphere, further impacting root processes. To explore these interesting interactions, in the present review, we firstly summarize current knowledge of physiological processes of NO production and consumption in roots and, thereafter, of processes involved in NO homeostasis in root cells with particular emphasis on root growth, development, nutrient acquisition, environmental stresses and organismic interactions.

Published
2020
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12. Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation

Author

Barbara Nawrot, Renata Kaczmarek, Andrew S. Marriott, Armel Houel, Sophia Kossida, A. L. Valadao, Nadine Laguette, K. Polak, Christelle Langevin, Dimitrios Vlachakis, Nigel J. Jones, Baptiste Auzemery, Isabelle K. Vila, Pierre Boudinot, Clara Taffoni, Thaneas Prabakaran, Stéphanie Déjardin, Jessica Guerra, Søren R. Paludan, Institut de génétique humaine (IGH), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Laboratory of Genetics, Agricultural University of Athens, Laboratory of Genetics, Department of Biomedicine, Aarhus University [Aarhus], Edge Hill University, Department of Bioorganic Chemistry Centre of Molecular and Macromolecular Studies Polish Academy of Sciences, Polish Academy of Sciences (PAN), Virologie et Immunologie Moléculaires (VIM (UR 0892)), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Department of Biochemistry, University of Liverpool, ANRS French National Research Agency (ANR) 109560, Fondation ARC pour la Recherche sur le Cancer PJA20141201605, Merck Sharp and Dohme Avenir (M.S.D.-GnoSTic), M.S.D., Prix Roger PROPICE pour la recherche sur le cancer du pancreas of the Fondation pour la Recherche Medicale (FRM), SIRIC Montpellier Cancer Grant INCa_Inserm_DGOS_12553, Research Development Fund grant from North West Cancer Research (UK), Novo Nordisk Foundation NNF18OC0030274, Lundbeckfonden R198-2015-171 R268-2016-3927, Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, CR863 CR968, European Project: 637763,H2020,ERC-2014-STG,CrIC(2015), European Project: 786602,ENVISION, Genetics Laboratory [Agricultural University of Athens], and Agricultural University of Athens

Subjects
[SDV]Life Sciences [q-bio], Inflammation, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, In vivo, medicine, Health and Medicine, Research Articles, Cancer, 030304 developmental biology, 0303 health sciences, Multidisciplinary, SciAdv r-articles, RNA, biochemical phenomena, metabolism, and nutrition, In vitro, eye diseases, 3. Good health, Cell biology, Sting, chemistry, 030220 oncology & carcinogenesis, Stimulator of interferon genes, bacteria, medicine.symptom, Ap4A, DNA, Research Article
Abstract

The LysRS-Ap4A axis impairs cGAS-STING pathway activation, delaying nucleic acid-driven innate immune responses., Inflammation is an essential part of immunity against pathogens and tumors but can promote disease if not tightly regulated. Self and non-self-nucleic acids can trigger inflammation, through recognition by the cyclic GMP-AMP (cGAMP) synthetase (cGAS) and subsequent activation of the stimulator of interferon genes (STING) protein. Here, we show that RNA:DNA hybrids can be detected by cGAS and that the Lysyl-tRNA synthetase (LysRS) inhibits STING activation through two complementary mechanisms. First, LysRS interacts with RNA:DNA hybrids, delaying recognition by cGAS and impeding cGAMP production. Second, RNA:DNA hybrids stimulate LysRS-dependent production of diadenosine tetraphosphate (Ap4A) that in turn attenuates STING-dependent signaling. We propose a model whereby these mechanisms cooperate to buffer STING activation. Consequently, modulation of the LysRS-Ap4A axis in vitro or in vivo interferes with inflammatory responses. Thus, altogether, we establish LysRS and Ap4A as pharmacological targets to control STING signaling and treat inflammatory diseases.

Published
2020
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14. Cloning and functional characterization ofLjPLT4, a plasma membrane xylitol H+- symporter fromLotus japonicus

Author

Ourania I. Pavli, Katerina I. Kalliampakou, Haralabia Boleti, Michael K. Udvardi, Panagiotis Katinakis, Rémi Lemoine, Laurence Maurousset, Emmanouil Flemetakis, Evangelia D. Kouri, Agricultural University of Athens, Laboratoire de parasitologie moléculaire = Molecular Parasitology Laboratory [Athènes], Institut Pasteur Hellénique, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Equipe Physiologie Moléculaire du Transport de Sucres (PhyMoTS), Laboratoire de catalyse en chimie organique (LACCO), Université de Poitiers-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Poitiers-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), The Samuel Roberts Noble Foundation, and This work was co-funded by the European Social fund and Greek national resources – project PYTHAGORAS II (funding of research groups in Agricultural University of Athens) (EF), and by the bi-lateral French-Greek program, Platon (Molecular and biochemical characterization of monosaccharide transporters in root nodules) (RL and EF). The work was also supported, in part, by the Max Planck Society (MKU).

Subjects
MESH: Symporters, 0106 biological sciences, DNA, Complementary, MESH: Lotus, legumes, Lotus japonicus, Arabidopsis, Saccharomyces cerevisiae, Xylose, Xylitol, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Monosaccharide transport, monosaccharide transport, [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, MESH: Arabidopsis, MESH: Cloning, Molecular, Cloning, Molecular, Molecular Biology, 030304 developmental biology, polyols, 0303 health sciences, Symporters, biology, Cell Membrane, MESH: Xylitol, food and beverages, Fructose, MESH: DNA, Complementary, Cell Biology, biology.organism_classification, MESH: Saccharomyces cerevisiae, Yeast, Plant Leaves, MESH: Plant Leaves, carbohydrates (lipids), xylitol, chemistry, Biochemistry, Symporter, Lotus, Sorbitol, MESH: Cell Membrane, 010606 plant biology & botany
Abstract

International audience; Polyols are compounds that play various physiological roles in plants. Here we present the identification of four cDNA clones of the model legume Lotus japonicus, encoding proteins of the monosaccharide transporter-like (MST) superfamily that share significant homology with previously characterized polyol transporters (PLTs). One of the transporters, named LjPLT4, was characterized functionally after expression in yeast. Transport assays revealed that LjPLT4 is a xylitol-specific H(+)-symporter (K (m), 0.34 mM). In contrast to the previously characterized homologues, LjPLT4 was unable to transport other polyols, including mannitol, sorbitol, myo-inositol and galactitol, or any of the monosaccharides tested. Interestingly, some monosaccharides, including fructose and xylose, inhibited xylitol uptake, although no significant uptake of these compounds was detected in the LjPLT4 transformed yeast cells, suggesting interactions with the xylitol binding site. Subcellular localization of LjPLT4-eYFP fusions expressed in Arabidopsis leaf epidermal cells indicated that LjPLT4 is localized in the plasma membrane. Real-time RT-PCR revealed that LjPLT4 is expressed in all major plant organs, with maximum transcript accumulation in leaves correlating with maximum xylitol levels there, as determined by GC-MS. Thus, LjPLT4 is the first plasma membrane xylitol-specific H(+)-symporter to be characterized in plants.

Published
2011
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15. Sequence analyses reveal that a TPR–DP module, surrounded by recombinable flanking introns, could be at the origin of eukaryotic Hop and Hip TPR–DP domains and prokaryotic GerD proteins

Author

Jacques Chomilier, Jorge Hernández Torres, Nikolaos Papandreou, Laboratorio de Biología Molecular, Escuela de Biología, Universidad Industrial de Santander, Universidad Industrial de Santander [Bucaramanga] (UIS), Genetics Laboratory [Agricultural University of Athens], Agricultural University of Athens, Institut de minéralogie et de physique des milieux condensés (IMPMC), Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Institut de Physique du Globe de Paris (IPG Paris)-Centre National de la Recherche Scientifique (CNRS), Laboratory of Genetics, Agricultural University of Athens, Laboratory of Genetics, and Université Pierre et Marie Curie - Paris 6 (UPMC)-IPG PARIS-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Hsp70 interacting protein, Molecular Sequence Data, Hydrophobic cluster analysis, repeat, TPR protein, Biology, Biochemistry, Protein Structure, Secondary, Hop (networking), Evolution, Molecular, 03 medical and health sciences, HSP organizing protein, Sequence Analysis, Protein, Animals, Humans, Gene family, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, HSP70 Heat-Shock Proteins, Amino Acid Sequence, HSP90 Heat-Shock Proteins, Peptide sequence, Gene, 030304 developmental biology, Genetics, Original Paper, 0303 health sciences, Hop, 030302 biochemistry & molecular biology, Intron, Cell Biology, Introns, Protein Structure, Tertiary, Hsp70, Tetratricopeptide, Open reading frame, Eukaryotic Cells, Prokaryotic Cells, Molecular Chaperones
Abstract

International audience; The co-chaperone Hop [heat shock protein (HSP) organising protein] is known to bind both Hsp70 and Hsp90. Hop comprises three repeats of a tetratricopeptide repeat (TPR) domain, each consisting of three TPR motifs. The first and last TPR domains are followed by a domain containing several dipeptide (DP) repeats called the DP domain. These analyses suggest that the hop genes result from successive recombination events of an ancestral TPR– DP module. From a hydrophobic cluster analysis of homologous Hop protein sequences derived from gene families, we can postulate that shifts in the open reading frames are at the origin of the present sequences. Moreover, these shifts can be related to the presence or absence of biological function. We propose to extend the family of Hop co-chaperons into the kingdom of bacteria, as several structurally related genes have been identified by hydrophobic cluster analysis. We also provide evidence of common structural characteristics between hop and hip genes, suggesting a shared precursor of ancestral TPR–DP domains.

Published
2008
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16. Contribution to the Prediction of the Fold Code: Application to Immunoglobulin and Flavodoxin Cases

Author

Jacques Chomilier, Mateusz Banach, Barbara Kalinowska, Nikolaos Papandreou, Elodie Duprat, Irena Roterman, Mathilde Carpentier, Nicolas Prudhomme, Department of Bioinformatics and Telemedicine, Jagiellonian University - Medical College, Uniwersytet Jagielloński w Krakowie = Jagiellonian University (UJ)-Uniwersytet Jagielloński w Krakowie = Jagiellonian University (UJ), Institut de minéralogie, de physique des matériaux et de cosmochimie (IMPMC), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de recherche pour le développement [IRD] : UR206-Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS), RPBS, Genetics Department, Genetics Department Agricultural University of Athens, Muséum national d'Histoire naturelle (MNHN)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de recherche pour le développement [IRD] : UR206-Centre National de la Recherche Scientifique (CNRS), Genetics Laboratory [Agricultural University of Athens], Agricultural University of Athens-Agricultural University of Athens, Department of Bioinformatics, Telemedicine Jagiellonian University - Collegium Medicum, Muséum national d'Histoire naturelle (MNHN)-Institut de recherche pour le développement [IRD] : UR206-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), and Biophysics and Bioinformatics Laboratory

Subjects
Models, Molecular, Protein Folding, Globular protein, Science, [SDV]Life Sciences [q-bio], Protein domain, Flavodoxin, Immunoglobulins, Sequence alignment, Protein Structure, Secondary, Protein structure, Protein sequencing, Animals, Humans, Amino Acid Sequence, Peptide sequence, ComputingMilieux_MISCELLANEOUS, Physics, chemistry.chemical_classification, [SDV.GEN]Life Sciences [q-bio]/Genetics, Multidisciplinary, Binding Sites, Bacteria, Protein structure prediction, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], chemistry, Biochemistry, Medicine, Protein folding, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], Biological system, Hydrophobic and Hydrophilic Interactions, Monte Carlo Method, Algorithms, Research Article
Abstract

International audience; BackgroundFolding nucleus of globular proteins formation starts by the mutual interaction of a group of hydrophobic amino acids whose close contacts allow subsequent formation and stability of the 3D structure. These early steps can be predicted by simulation of the folding process through a Monte Carlo (MC) coarse grain model in a discrete space. We previously defined MIRs (Most Interacting Residues), as the set of residues presenting a large number of non-covalent neighbour interactions during such simulation. MIRs are good candidates to define the minimal number of residues giving rise to a given fold instead of another one, although their proportion is rather high, typically [15-20]% of the sequences. Having in mind experiments with two sequences of very high levels of sequence identity (up to 90%) but different folds, we combined the MIR method, which takes sequence as single input, with the “fuzzy oil drop” (FOD) model that requires a 3D structure, in order to estimate the residues coding for the fold. FOD assumes that a globular protein follows an idealised 3D Gaussian distribution of hydrophobicity density, with the maximum in the centre and minima at the surface of the “drop”. If the actual local density of hydrophobicity around a given amino acid is as high as the ideal one, then this amino acid is assigned to the core of the globular protein, and it is assumed to follow the FOD model. Therefore one obtains a distribution of the amino acids of a protein according to their agreement or rejection with the FOD model.ResultsWe compared and combined MIR and FOD methods to define the minimal nucleus, or keystone, of two populated folds: immunoglobulin-like (Ig) and flavodoxins (Flav). The combination of these two approaches defines some positions both predicted as a MIR and assigned as accordant with the FOD model. It is shown here that for these two folds, the intersection of the predicted sets of residues significantly differs from random selection. It reduces the number of selected residues by each individual method and allows a reasonable agreement with experimentally determined key residues coding for the particular fold. In addition, the intersection of the two methods significantly increases the specificity of the prediction, providing a robust set of residues that constitute the folding nucleus.

Published
2015
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17. Investigation of the similarities between NDVI maps from different proximal and remote sensing platforms in explaining vineyard variability

Author

A. Kasimati, V. Psiroukis, N. Darra, A. Kalogrias, D. Kalivas, J. A. Taylor, S. Fountas, Agricultural University of Athens, Technologies et Méthodes pour les Agricultures de demain (UMR ITAP), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Montpellier, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), and European Project: 780751,BigDatagrapes

Subjects
Yield, Total soluble solids, Fuzzy clustering, Satellite, UAV, [SDV.SA.STA]Life Sciences [q-bio]/Agricultural sciences/Sciences and technics of agriculture, General Agricultural and Biological Sciences, Management units, Precision viticulture
Abstract

Vegetation indices (VI), especially the normalised difference vegetation index (NDVI), are used to determine management units (MU) and to explain quantity and quality of vineyard production. How do NDVI maps from different sensing technologies differ in a production context? What part of the variability of yield and quality can they explain? This study compares high-resolution multispectral, multi-temporal data from CropCircle, SpectroSense + GPS, Parrot Sequoia + multispectral camera equipped UAV, and Sentinel-2 imagery over two seasons (2019 and 2020). The objective was to assess whether the date of data collection (phenological growth stage) influences the correlations between NDVI and crop production. The comparison of vineyard NDVI data from proximal and remote sensing in both a statistical and a productive context showed strong similarities between NDVI values from similar sensors (0.69

Published
2022
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18. PREDICTION OF CHIMERIC PROTEIN FOLD

Author

Ruben Acuna, Zoé Lacroix, Nikolaos Papandreou, Fayez Hadji, Jacques Chomilier, Scientific Data Management Laboratory, Arizona State University, Arizona State University [Tempe] (ASU), Institut de minéralogie et de physique des milieux condensés (IMPMC), Université Pierre et Marie Curie - Paris 6 (UPMC)-IPG PARIS-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Ressource Parisienne en Bioinformatique Structurale, Genetics Department, Agricultural University of Athens, Genetics Department, Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Institut de Physique du Globe de Paris (IPG Paris)-Centre National de la Recherche Scientifique (CNRS), Genetics Laboratory [Agricultural University of Athens], and Agricultural University of Athens

Subjects
060201 languages & linguistics, 030504 nursing, Fold (higher-order function), Chemistry, Ab initio, Fusion Proteins, Folding, MIR, Sequence (biology), 06 humanities and the arts, Computational biology, Folding (DSP implementation), Fusion protein, 03 medical and health sciences, Chimeric Proteins, 0602 languages and literature, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Protein folding, Prediction, 0305 other medical science, Peptide sequence, Gene, Simulation
Abstract

International audience; We propose two computational methods for predicting if a protein produced by fusion of genes will conserve the structures of the fused proteins. We use two complementary paths for prediction. The former is a simulation from the sequence while the latter exploits its expected structure. Early stages of protein folding are simulated from their amino acid sequence by capturing the most interacting residues (MIR). Individual domain structures (or models) are superposed onto the predicted complex structure (or model). When no structure exists, a model is calculated using a set of ab initio and fold recognition tools. These results are used to predict the validity of the chimeric protein. We test the two methods against a dataset of 10 proteins.

Published
2012
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19. The future of small farms and small food businesses as actors in regional food security: a participatory scenario analysis from Europe and Africa

Author

Dionisio Ortiz-Miranda, Olga Moreno-Pérez, Laura Arnalte-Mur, Pedro Cerrada-Serra, Victor Martinez-Gomez, Barbara Adolph, Joanes Atela, Sylvester Ayambila, Isaurinda Baptista, Raluca Barbu, Hilde Bjørkhaug, Marta Czekaj, Dominic Duckett, Arlindo Fortes, Francesca Galli, Giannis Goussios, Paola Andrea Hernández, Pavlos Karanikolas, Kennedy Machila, Elpiniki Oikonomopoulou, Paolo Prosperi, María Rivera, Łukasz Satoła, Monika Szafrańska, Talis Tisenkopfs, Charles Tonui, Richard Yeboah, Universitat Politècnica de València (UPV), International Institute for Environment and Development (IIED), African Centre for Technology Studies, Partenaires INRAE, Department of Biotechnology, Faculty of Agriculture, University for Development Studies, Tamale, Ghana, Universidade de Cabo Verde (UNICV), Highclere Consulting, Institute for Rural and Regional Research, University of Agriculture in Krakow, Glasgow Caledonian University (GCU), Department of Agricultural, Food and Environmental Science, University of Pisa, Pisa, Agricultural University of Athens, Lilongwe University of Agriculture and Natural Resources, P.O Box 219, Lilongwe, Malawi, Montpellier Interdisciplinary center on Sustainable Agri-food systems (Social and nutritional sciences) (UMR MoISA), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Centre International de Hautes Etudes Agronomiques Méditerranéennes - Institut Agronomique Méditerranéen de Montpellier (CIHEAM-IAMM), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Montpellier, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Centre International de Hautes Etudes Agronomiques Méditerranéennes - Institut Agronomique Méditerranéen de Montpellier (CIHEAM-IAMM), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM), Universidade de Évora, baltic studies centre, and European Project: 677363,H2020,H2020-SFS-2015-2,SALSA(2016)

Subjects
AFRICA, EUROPE, Sociology and Political Science, SCENARIO, Geography, Planning and Development, PARTICIPATION, [SDV.SA.AGRO]Life Sciences [q-bio]/Agricultural sciences/Agronomy, Development, ACTOR, COMPARATIVE ANALYSIS, AGROFOOD SYSTEM, HUMAN NUTRITION, FORECASTING, PETITE EXPLOITATION AGRICOLE, PME, PROSPECTIVE, ACTEUR, SMALL FARMS, SECURITE ALIMENTAIRE, SYSTEME AGROALIMENTAIRE, FOOD SECURITY, SME, [SHS.ECO]Humanities and Social Sciences/Economics and Finance, NUTRITION HUMAINE, AFRIQUE, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, ANALYSE COMPARATIVE
Abstract

International audience; This paper presents the cross-regional comparative analysis of a participatory scenario planning exercise conducted in 13 regions of 13 countries in both Europe and Africa as part of the H2020 research project SALSA “Small farms, small food business and sustainable food security”. The objective of the analysis is threefold: (i) to better understand how small farms and small food businesses would perform, in terms of their contribution to regional food and nutrition security, in a set of common scenarios for the year 2050; (ii) to assess how the evolution of certain drivers of change could impact on their future situation, and (iii) to derive some policy implications aimed to preserve and strengthen their capacity to contribute to food and nutrition security.

Published
2022
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20. Innovative education for sustainable development in peripheral rural areas

Author

Gaki, D., Felekis, S., Vlahos, G., Herzon, I., Morales Fusté, M. P., Tristan Berchoux, Bennettcoady, R., Jitea, I. M., Kazakova, Y., Kessari, M., Klepac, O., Mihai, V., Moran, J., Tolic, S., Roglic, M., University of Thessaly [Volos] (UTH), Agricultural University of Athens, TKK Helsinki University of Technology (TKK), Centre International de Hautes Etudes Agronomiques Méditerranéennes - Institut Agronomique Méditerranéen de Montpellier (CIHEAM-IAMM), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM), Territoires, Environnement, Télédétection et Information Spatiale (UMR TETIS), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-AgroParisTech-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Galway-Mayo Institute of Technology, University of Agricultural Sciences and Veterinary Medicine Cluj Napoca = Universitatea de Științe Agricole și Medicină Veterinară Cluj-Napoca, University of National and World Economy [Sofia] (UNWE), Montpellier Interdisciplinary center on Sustainable Agri-food systems (Social and nutritional sciences) (UMR MoISA), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Centre International de Hautes Etudes Agronomiques Méditerranéennes - Institut Agronomique Méditerranéen de Montpellier (CIHEAM-IAMM), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Montpellier, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), University of Osijek, and Theodoridis A. (ed.), Koutsou S. (ed.)

Subjects
[SHS.EDU]Humanities and Social Sciences/Education, BULGARIA, FRANCE, ENSEIGNEMENT A DISTANCE, DISTANCE STUDY, DATABASES, BULGARIE, ACTOR, BANQUE DE DONNEES, GRECE, GREECE, RURAL AREAS, INNOVATION PEDAGOGIQUE, CROATIA, CROATIE, ACTEUR, ROUMANIE, ROUMANIA, PROGRAMME ERASMUS, FORMATION AGRICOLE, CONSEILLER AGRICOLE, FINLANDE, ADVISORY OFFICERS, FINLAND, ZONE RURALE, AGRICULTURAL TRAINING, CASE STUDIES, ETUDE DE CAS, IRELANDE, DEVELOPPEMENT DURABLE, SUSTAINABLE DEVELOPMENT, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, HIGH NATURE VALUE, IRLANDE, EDUCATIONAL INNOVATION, ERASMUS PROGRAMME, HAUTE VALEUR NATURELLE
Abstract

International audience; This paper aims to present the results of the Erasmus + RUR'UP project that developed educational tools for scientists, public managers, practitioners, and agricultural advisors living and working in peripheral rural areas. Based on the assessment of the educational needs and gaps for the sustainable development of the EU peripheral rural areas of Greece.

Published
2022

21. MilKey project: 'Decision support system for sustainable and GHG optimised milk production in key European areas' Sustainability assessment of dairy production systems Guide for the collection of farm environmental and economic data

Author

Baillet, Vincent, Balaine, Lorraine, Krol, Dominika, Amon, Barbara, Wilfart, Aurélie, Alem, Habtamu, Anestis, Vasileios, Bartzanas, Thomas, Breen, James, Buckley, Cathal, Castellan, Elisabeth, Dach, Jacek, Dragoni, Federico, Johansen, Astrid, Jørgensen, Grete, Lien, Gudbrand, Rychla, Anna, Wawrzyniak, Agnieszka, Winiwarter, Wilfried, Sol Agro et hydrosystème Spatialisation (SAS), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Rennes Angers, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Teagasc - The Agriculture and Food Development Authority (Teagasc), Leibniz-Institut für Agrartechnik und Bioökonomie (ATB), Norsk institutt for bioøkonomi=Norwegian Institute of Bioeconomy Research (NIBIO), Agricultural University of Athens, University College Dublin [Dublin] (UCD), Institut de l'élevage, Institut de l'élevage (IDELE), Poznan University of Life Sciences (Uniwersytet Przyrodniczy w Poznaniu) (PULS), Norsk Landbruksrådgiving (NLR), Norway, University of Zielona Góra, International Institute for Applied Systems Analysis (IIASA), Ecosystems Services and Management, Schlossplatz 1, A-2361 Laxenburg, Austria, INRAE, and European Project

Subjects
Sustainability assessment, [SDV.SA.SPA]Life Sciences [q-bio]/Agricultural sciences/Animal production studies, Data collection, Economic sustainability, Environmental sustainability, Guide
Abstract

The MilKey project aims at assessing the environmental, economic, and social sustainability of European dairy production systems, and at identifying ‘win-win’ farmingpractices for sustainable and greenhouse gas (GHG) optimised milk production.This data collection guide was prepared to guide stakeholders wishing to conduct a sustainability assessment of dairy production systems. Specifically, the document can beused to facilitate the process of collecting and reporting the farm environmental and economic information necessary to conduct a sustainability assessment based on the MilKeydata template. The guide gathers and defines all variables included in the first four parts of the MilKey data template (i.e., Part I: General farm information and crop production,Part II: Dairy enterprise, Part III: Beef enterprise, and Part IV: Economic data).

Published
2022

22. Quantitative Prediction of Critical Amino Acid Positions for Protein Folding

Author

Jacques Chomilier, Trias Thireou, Vassilios Atlamazoglou, Elias Eliopoulos, Mathieu Lonquety, Nikolaos Papandreou, Genetics Laboratory [Agricultural University of Athens], Agricultural University of Athens, Institut de minéralogie et de physique des milieux condensés (IMPMC), Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Institut de Physique du Globe de Paris (IPG Paris)-Centre National de la Recherche Scientifique (CNRS), Laboratory of Genetics, Agricultural University of Athens, Laboratory of Genetics, and Université Pierre et Marie Curie - Paris 6 (UPMC)-IPG PARIS-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)

Subjects
monte carlo method, Saccharomyces cerevisiae Proteins, lattice simulation, Protein Conformation, information science, Protein Data Bank (RCSB PDB), Ab initio prediction, Biochemistry, 03 medical and health sciences, Protein structure, Structural Biology, natural sciences, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Amino Acid Sequence, Protein folding, Databases, Protein, Peptide sequence, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Chemistry, 030302 biochemistry & molecular biology, Microfilament Proteins, Proteins, Reproducibility of Results, General Medicine, Protein structure prediction, Amino acid, hydrophobic core, Crystallography, health occupations, Closed loop, folding nucleus, Algorithms
Abstract

International audience; The prediction of structural elements from the sequence is not only useful in determining the fold and function of proteins with unknown structure, but is also valuable in the design of protein engineering experiments, by locating critical regions of the polypeptide chain, with respect to folding and stability. Both thermodynamic and topological criteria have been used to define such amino acid sequence regions. The notion of folding nucleus comes from a thermodynamic view of folding, as the minimum set of amino acid residues necessary for the formation of a stable protein core [1]. The amino acids of the folding nucleus can be found experimentally by means of protein engineering studies [2]. However, it is difficult to perform this kind of experiments on a large scale. Therefore very limited data are actually available [3, 4, 5, 6]. An original topological analysis of available protein structures taken from the PDB [7], revealed a new property, common to almost all globular proteins: Closed Loops [8] or equivalently, TEFs (for Tightened-Ended-Fragments) [9, 10], are fragments with two basic properties: a) Their ends are located in the protein core and b) Their ends are close to each other in 3D space (C

Published
2009

23. SPROUTS: a database for the evaluation of protein stability upon point mutation

Author

Zoé Lacroix, Mathieu Lonquety, Jacques Chomilier, Nikolaos Papandreou, Institut de minéralogie et de physique des milieux condensés (IMPMC), Université Pierre et Marie Curie - Paris 6 (UPMC)-IPG PARIS-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), University of Arizona, Laboratory of Genetics, Agricultural University of Athens, Laboratory of Genetics, Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Institut de Physique du Globe de Paris (IPG Paris)-Centre National de la Recherche Scientifique (CNRS), Genetics Laboratory [Agricultural University of Athens], and Agricultural University of Athens

Subjects
Protein Folding, Protein Conformation, [SDV]Life Sciences [q-bio], Biology, computer.software_genre, 03 medical and health sciences, Protein stability, Protein structure, Computer Graphics, Genetics, Point Mutation, Databases, Protein, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, 0303 health sciences, Database, Protein Stability, Point mutation, 030302 biochemistry & molecular biology, Proteins, Articles, Folding (DSP implementation), Mutation (genetic algorithm), Protein folding, Utility system, computer
Abstract

SPROUTS (Structural Prediction for pRotein fOlding UTility System) is a new database that provides access to various structural data sets and integrated functionalities not yet available to the community. The originality of the SPROUTS database is the ability to gain access to a variety of structural analyses at one place and with a strong interaction between them. SPROUTS currently combines data pertaining to 429 structures that capture representative folds and results related to the prediction of critical residues expected to belong to the folding nucleus: the MIR (Most Interacting Residues), the description of the structures in terms of modular fragments: the TEF (Tightened End Fragments), and the calculation at each position of the free energy change gradient upon mutation by one of the 19 amino acids. All database results can be displayed and downloaded in textual files and Excel spreadsheets and visualized on the protein structure. SPROUTS is a unique resource to access as well as visualize state-of-the-art characteristics of protein folding and analyse the effect of point mutations on protein structure. It is available at http://bioinformatics.eas.asu.edu/sprouts.html.

Published
2009
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24. a database for the evaluation of protein stability upon point mutation

Author

Lonquety, Mathieu, Lacroix, Zoe', Papandreou, Nikolaos, Chomilier, Jacques, Scientific Data Management Laboratory, Arizona State University, Arizona State University [Tempe] (ASU), Institut de minéralogie et de physique des milieux condensés (IMPMC), Université Pierre et Marie Curie - Paris 6 (UPMC)-IPG PARIS-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), The Translational Genomics Research Institute (TGen), Laboratory of Genetics, Agricultural University of Athens, Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Institut de Physique du Globe de Paris (IPG Paris)-Centre National de la Recherche Scientifique (CNRS), Genetics Laboratory [Agricultural University of Athens], and Agricultural University of Athens

Subjects
[SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Abstract

International audience; (Structural Prediction for pRotein fOlding UTility System) is a new database that provides access to various structural data sets and integrated functionalities not yet available to the community. The originality of the SPROUTS database is the ability to gain access to a variety of structural analyses at one place and with a strong interaction between them. SPROUTS currently combines data pertaining to 429 structures that capture representative folds and results related to the prediction of critical residues expected to belong to the folding nucleus: the MIR (Most Interacting Residues), the description of the structures in terms of modular fragments: the TEF (Tightened End Fragments), and the calculation at each position of the free energy change gradient upon mutation by one of the 19 amino acids. All database results can be displayed and downloaded in textual files and Excel spreadsheets and visualized on the protein structure. SPROUTS is a unique resource to access as well as visualize state-of-the-art characteristics of protein folding and analyse the effect of point mutations on protein structure.

Published
2009

25. Universal positions in globular proteins From observation to simulation

Author

Nikolaos Papandreou, Jacques Chomilier, Anne Lopes, Igor N. Berezovsky, Elias Eliopoulos, Laboratory of Genetics, Agricultural University of Athens, Department of Structural Biology, Weizmann Institute of Science [Rehovot, Israël], Department of Chemistry and Chemical Biology, Harvard University [Cambridge], Institut de minéralogie et de physique des milieux condensés (IMPMC), Université Pierre et Marie Curie - Paris 6 (UPMC)-IPG PARIS-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Harvard University, Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Institut de Physique du Globe de Paris (IPG Paris)-Centre National de la Recherche Scientifique (CNRS), Genetics Laboratory [Agricultural University of Athens], Laboratoire de Biochimie de l'Ecole polytechnique (BIOC), École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Genetics Laboratory, Department of Agricultural Biotechnology, and Laboratory of Genetics, Agricultural University of Athens

Subjects
chemistry.chemical_classification, 0303 health sciences, lattice simulation, Chemistry, Globular protein, [SDV]Life Sciences [q-bio], 030303 biophysics, Structural alignment, Phi value analysis, Fold (geology), Contact order, Biochemistry, hydrophobic core, 03 medical and health sciences, Crystallography, protein folding, Lattice protein, Protein folding, Folding funnel, folding nucleus, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology
Abstract

The description of globular protein structures as an ensemble of contiguous 'closed loops' or 'tightened end fragments' reveals fold elements crucial for the formation of stable structures and for navigating the very process of protein folding. These are the ends of the loops, which are spatially close to each other but are situated apart in the polypeptide chain by 25-30 residues. They also correlate with the locations of highly conserved hydrophobic residues (referred to as topohydrophobic), in a structural alignment of the members of a protein family. This study analysed these positions in 111 representatives of different protein folds, and then carried out dynamic Monte Carlo simulations of the first steps of the folding process, aimed at predicting the origins of the assembling folds. The simulations demonstrated that there is an obvious trend for certain sets of residues, named 'mostly interacting residues', to be buried at the early stages of the folding process. Location of these residues at the loop ends and correlation with topohydrophobic positions are demonstrated, thereby giving a route to simulations of the protein folding process.

Published
2004
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26. Genomic diversity and population structure of the indigenous Greek and Cypriot cattle populations

Author

Dimitris, Papachristou, Panagiota, Koutsouli, George P, Laliotis, Elisabeth, Kunz, Maulik, Upadhyay, Doris, Seichter, Ingolf, Russ, Bunevski, Gjoko, Nikolaos, Kostaras, Iosif, Bizelis, Ivica, Medugorac, Agricultural University of Athens, Ludwig-Maximilians-Universität München (LMU), and Ss. Cyril and Methodius University in Skopje

Subjects
Reproductive Isolation, [SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE], Greece, lcsh:QH426-470, Genetic Introgression, Polymorphism, Single Nucleotide, humanities, [SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics, lcsh:Genetics, Gene Frequency, Cyprus, Animals, Cattle, lcsh:Animal culture, geographic locations, Research Article, lcsh:SF1-1100
Abstract

International audience; Background: The indigenous cattle populations from Greece and Cyprus have decreased to small numbers and are currently at risk of extinction due to socio-economic reasons, geographic isolation and crossbreeding with commercial breeds. This study represents the first comprehensive genome-wide analysis of 10 indigenous cattle populations from continental Greece and the Greek islands, and one from Cyprus, and compares them with 104 international breeds using more than 46,000 single nucleotide polymorphisms (SNPs).Results: We estimated several parameters of genetic diversity (e.g. heterozygosity and allelic diversity) that indicated a severe loss of genetic diversity for the island populations compared to the mainland populations, which is mainly due to the declining size of their population in recent years and subsequent inbreeding. This high inbreeding status also resulted in higher genetic differentiation within the Greek and Cyprus cattle group compared to the remaining geographical breed groups. Supervised and unsupervised cluster analyses revealed that the phylogenetic patterns in the indigenous Greek breeds were consistent with their geographical origin and historical information regarding crosses with breeds of Anatolian or Balkan origin. Cyprus cattle showed a relatively high indicine ancestry. Greek island populations are placed close to the root of the tree as defined by Gir and the outgroup Yak, whereas the mainland breeds share a common historical origin with Buša. Unsupervised clustering and D-statistics analyses provided strong support for Bos indicus introgression in almost all the investigated local cattle breeds along the route from Anatolia up to the southern foothills of the Alps, as well as in most cattle breeds along the Apennine peninsula to the southern foothills of the Alps.Conclusions: All investigated Cyprus and Greek breeds present complex mosaic genomes as a result of historical and recent admixture events between neighbor and well-separated breeds. While the contribution of some mainland breeds to the genetic diversity pool seems important, some island and fragmented mainland breeds suffer from a severe decline of population size and loss of alleles due to genetic drift. Conservation programs that are a compromise between what is feasible and what is desirable should focus not only on the still highly diverse mainland breeds but also promote and explore the conservation possibilities for island breeds.

Published
2020
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27. Performance of a Prototype Boom Sprayer for Bed-Grown Carrots Based on Canopy Deposition Optimization, Ground Losses and Spray Drift Potential Mitigation in Semi-Field Conditions

Author

Aude Lamare, Ingrid Zwertvaegher, David Nuyttens, Paolo Balsari, Paolo Marucco, Marco Grella, Amedeo Caffini, Nikos Mylonas, Spyros Fountas, Jean-Paul Douzals, Technologies et Méthodes pour les Agricultures de demain (UMR ITAP), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Montpellier, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Research Institute for Agricultural, Fisheries and Food (ILVO), Università degli studi di Torino = University of Turin (UNITO), Auteur indépendant, Agricultural University of Athens, This research was funded by European Union's Horizon 2020 research and innovation program under grant agreement number 773718 (OPTIMA-project)., and European Project: 773718

Subjects
Fluid Flow and Transfer Processes, nozzle type, Process Chemistry and Technology, [SDV]Life Sciences [q-bio], General Engineering, spray drift potential, bed-grown crop, air support, spray deposition, spray drift potential, smart sprayer, nozzle type, Computer Science Applications, spray deposition, General Materials Science, smart sprayer, Instrumentation, bed-grown crop, air support
Abstract

International audience; The H2020-project OPTIMA concept of smart sprayer relies on several functionalities, including variable nozzle spacing for bed-grown carrots, based on an air-assisted boom sprayer. A prototype boom was designed and evaluated though canopy deposition, ground losses, and spray drift potential. Four bed spray configurations, including various nozzle types, angles, and sizes (XR8004, combination of AIUB8504/AI11004, AI8004, and XR8002) at the most appropriate nozzle spacing and height, were tested and compared to a broadcast application (XR11004). Deposition measurements were performed on carrots in bins at early and full-grown stages with respective target zone width of 1.4 m and 2.2 m. Spray drift potential measurements were performed following ISO 22401, 2015. The spray boom was equipped with an air sleeve providing different air speeds (0, 4, 8 m s−1). The relative depositions at both growth stages showed a significant effect of spray configuration and lowest values were found for the broadcast application. The configurations consisting of air inclusion nozzles generated the lowest drift potential compared to the broadcast application, although not significantly different. Bed spray configurations can thus improve canopy depositions and spray drift potential compared to a conventional broadcast application when the boom height and the nozzle spacing are adjusted to the growth stage.

Published
2022
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28. Influence of temperature on regulation of key virulence and stress response genes in Listeria monocytogenes biofilms

Author

Sofia V. Poimenidou, Nelly Caccia, Spiros Paramithiotis, Michel Hébraud, George-John Nychas, Panagiotis N. Skandamis, Agricultural University of Athens, Microbiologie Environnement Digestif Santé (MEDIS), and Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Clermont Auvergne (UCA)

Subjects
Virulence, Collagen binding proteins, Stress response, [SDV]Life Sciences [q-bio], Putative binding proteins, Microbiology, Fibronectin binding proteins, Food Science
Abstract

International audience; Temperature is a major determinant of Listeria (L.) monocytogenes adherence and biofilm formation on abiotic surfaces. However, its role on gene regulation of L. monocytogenes mature biofilms has not been investigated. In the present study, we aimed to evaluate the impact of temperature up-and down-shift on L. monocytogenes biofilms gene transcription. L. monocytogenes strain EGD-e biofilms were first developed on stainless steel surfaces in Brain Heart Infusion broth at 20 • C for 48 h. Then, nutrient broth was renewed, and mature biofilms were exposed to 10 • C, 20 • C or 37 • C for 24 h. Biofilm cells were harvested and RNA levels of plcA, prfA, hly, mpl, plcB, sigB, bapL, fbpA, fbpB, lmo2178, lmo0880, lmo0160, lmo1115, lmo 2089, lmo2576, lmo0159 and lmo0627 were evaluated by quantitative RT-PCR. The results revealed an over-expression of all genes tested in biofilm cells compared to planktonic cells. When biofilms were further allowed to proliferate at 20 • C for 24 h, the transcription levels of key virulence, stress response and putative binding proteins genes plcA, sigB, fbpA, fbpB, lmo1115, lmo0880 and lmo2089 decreased. A temperature-dependent transcription for sigB, plcA, hly, and lmo2089 genes was observed after biofilm proliferation at 10 • C or 37 • C. Our findings suggest that temperature differentially affects gene regulation of L. monocytogenes mature biofilms, thus modulating attributes such as virulence, stress response and pathogenesis.

Published
2023
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29. Farmers' networks and the quest for reliable advice: innovating in Greece

Author

Koutsouris, Alex, Zarokosta, Eleni, Agricultural University of Athens, H2020 : 727577, and European Project: 727577,H2020-RUR-2016-2,AgriLink(2017)

Subjects
2. Zero hunger, Geography, Planning and Development, 0211 other engineering and technologies, 021107 urban & regional planning, 04 agricultural and veterinary sciences, 02 engineering and technology, Education, [SHS]Humanities and Social Sciences, microAKIS, 'Triggering Change Model', knowledge transfer/exchange, 040103 agronomy & agriculture, 0401 agriculture, forestry, and fisheries, social capital, General Agricultural and Biological Sciences, extension/ advisory services, innovation adoption/ diffusion
Abstract

Purpose The paper aims at better understanding the micro-foundations of current institutional changes in agricultural knowledge and innovation systems (AKIS). Design A survey of 98 farmers and interviews with 37 advice providers in south-western France were conducted to analyse the ways in which farmers combine different sources of advice (microAKIS). The farmers’ practices were observed for general farm management and for 3 types of innovation (new crop diversification, digital decision support tools, and labour outsourcing). Findings The results highlight poorly-known characteristics of microAKIS regarding the variety of sources of advice used by farmers, and the limited number of reliable resources on which farmers can draw at key stages of the innovation process. They provide evidence of bottom-up mechanisms of institutional changes such as the routinization of the use of certain service providers that are often overlooked in AKIS analyses (e.g. upstream industries). Practical implications These results can contribute to reducing the misalignments of stakeholders’ representations of AKIS and microAKIS, and therefore facilitate public debates and improve the efficiency of interventions in this area. Theoretical implications Studies of institutional changes resulting from the evolution of microAKIS are expected to complement analyses of increased pluralism of advice providers. Originality Linking the observation of microAKIS and the analysis of incremental institutional changes in AKIS allows the identification of transformations of the AKIS rationale that would otherwise remain partially invisible.

Published
2022
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30. Global patterns in genomic diversity underpinning the evolution of insecticide resistance in the aphid crop pest Myzus persicae

Author

Jean-Christophe Simon, Adam Pym, Joanna Mackisack, Alexander Hayward, Pablo Bielza, Kamel Charaabi, John Vontas, Hannah J. Burrack, Chris Bass, Ralf Nauen, Young-Nam Youn, Ilona Stepanyan, Ana Duarte, Fabrice Legeai, Gao Xiwu, Richard H. ffrench-Constant, Christoph T. Zimmer, Kumar Saurabh Singh, Bartlomiej J. Troczka, Guangwei Ren, Alex C.C. Wilson, Stéphanie Robin, Thomas C. Mathers, Christian C. Figueroa, Claudio C. Ramírez, Erick M. G. Cordeiro, Georg Jander, Martin S. Williamson, Ian Denholm, Emanuele Mazzoni, John T. Margaritopoulos, Paul A Umina, Nina V. Voronova, University of Exeter, Escola Superior de Agricultura 'Luiz de Queiroz' (ESALQ), Universidade de São Paulo (USP), John Innes Centre [Norwich], Institut de Génétique, Environnement et Protection des Plantes (IGEPP), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Scalable, Optimized and Parallel Algorithms for Genomics (GenScale), Inria Rennes – Bretagne Atlantique, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-GESTION DES DONNÉES ET DE LA CONNAISSANCE (IRISA-D7), Institut de Recherche en Informatique et Systèmes Aléatoires (IRISA), Université de Bretagne Sud (UBS)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National de Recherche en Informatique et en Automatique (Inria)-École normale supérieure - Rennes (ENS Rennes)-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-CentraleSupélec-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université de Bretagne Sud (UBS)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Institut de Recherche en Informatique et Systèmes Aléatoires (IRISA), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-École normale supérieure - Rennes (ENS Rennes)-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Technical University of Cartagena (UPTC), North Carolina State University [Raleigh] (NC State), University of North Carolina System (UNC), Institut Supérieur de Biotechnologie de Sidi Thabet (ISBST), Université de la Manouba [Tunisie] (UMA), University of Hertfordshire [Hatfield] (UH), Universidad de Talca, Boyce Thompson Institute [Ithaca], Hellenic Agricultural Organization Demeter (HAO Demeter), Università cattolica del Sacro Cuore [Milano] (Unicatt), Bayer Pharma AG [Berlin], Chinese Academy of Agricultural Sciences (CAAS), National Academy of Sciences of the Republic of Armenia [Yerevan] (NAS RA), School of BioSciences [Melbourne], Faculty of Science [Melbourne], University of Melbourne-University of Melbourne, Belarusian State University, Foundation for Research and Technology - Hellas (FORTH), Agricultural University of Athens, Rothamsted Research, University of Miami [Coral Gables], China Agricultural University (CAU), Chungnam National University (CNU), This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement no. 646625), and the Biotechnology and Biological Sciences Research Council (BBSRC) (grant number: BB/S006060/1). Illumina sequencing of clone 126 was funded by Defense Advanced Research Projects Agency (DARPA) agreement HR0011-17-2-0053 to G.J. A.C.C.W. was supported by National Science Foundation Award IOS-1354154. A.H. is supported by a BBSRC David Phillips Fellowship (BB/N020146/1), and T.C.M. by a BBSRC Future Leaders Fellowship (BB/R01227X/1)., European Project: 646625,H2020,ERC-2014-CoG,P450RESIST(2016), Universidade de São Paulo = University of São Paulo (USP), Biotechnology and Biological Sciences Research Council (BBSRC), Université de Rennes (UR)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-INSTITUT AGRO Agrocampus Ouest, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-Institut National de Recherche en Informatique et en Automatique (Inria)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Universidad Politécnica de Cartagena / Technical University of Cartagena (UPCT), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-Institut National de Recherche en Informatique et en Automatique (Inria)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université de Rennes 1 (UR1), and Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique)

Subjects
Insecticides, [SDV]Life Sciences [q-bio], Genome, Insect, Myzus persicae, Medicine (miscellaneous), Sequence assembly, Insect, Insecticide Resistance, RESISTÊNCIA GENÉTICA ANIMAL, 0302 clinical medicine, Host races association, Biology (General), Pyrethroid insecticides, Phylogeny, media_common, 0303 health sciences, Aphid, biology, Geography, Sodium channel, food and beverages, Genomics, Plants, Peach-potato aphid, Settore AGR/11 - ENTOMOLOGIA GENERALE E APPLICATA, General Agricultural and Biological Sciences, Agricultural genetics, QH301-705.5, media_common.quotation_subject, Locus (genetics), Polymorphism, Single Nucleotide, General Biochemistry, Genetics and Molecular Biology, Article, Evolutionary genetics, Host-Parasite Interactions, Evolution, Molecular, Hemiptera, 03 medical and health sciences, Sequence Homology, Nucleic Acid, Animals, Genetic variation, genome, 030304 developmental biology, Resistance (ecology), Base Sequence, Genetic Variation, 15. Life on land, biology.organism_classification, Evolutionary biology, Aphids, Mutation, Adaptation, 030217 neurology & neurosurgery, Diversity (politics)
Abstract

The aphid Myzus persicae is a destructive agricultural pest that displays an exceptional ability to develop resistance to both natural and synthetic insecticides. To investigate the evolution of resistance in this species we generated a chromosome-scale genome assembly and living panel of >110 fully sequenced globally sampled clonal lines. Our analyses reveal a remarkable diversity of resistance mutations segregating in global populations of M. persicae. We show that the emergence and spread of these mechanisms is influenced by host–plant associations, uncovering the widespread co‐option of a host-plant adaptation that also offers resistance against synthetic insecticides. We identify both the repeated evolution of independent resistance mutations at the same locus, and multiple instances of the evolution of novel resistance mechanisms against key insecticides. Our findings provide fundamental insights into the genomic responses of global insect populations to strong selective forces, and hold practical relevance for the control of pests and parasites., Singh, Bass and colleagues generate new genomic resources for the aphid crop pest, Myzus persicae, comprising a chromosome-scale genome assembly and resequenced genomes of >100 globally sampled clonal lines. Using this dataset, they uncover both mechanisms underpinning the evolution of insecticide resistance and ecological factors that influence its emergence and spread.

Published
2021
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32. A critical analysis of the potential for EU Common Agricultural Policy measures to support wild pollinators on farmland

Author

Jeroen Scheper, Anikó Kovács-Hostyánszki, Jacobus C. Biesmeijer, Maj Rundlöf, Robert Chlebo, Mario V. Balzan, Nieke Knoben, Lynn V. Dicks, Jane C. Stout, Menelaos C. Stavrinides, Simon G. Potts, John M. Holland, Bernard E. Vaissière, Androulla Varnava, Penelope J. Bebeli, M. J. Suso, H. N. Panou, Danilo Bevk, Chris Hartfield, Ignasi Bartomeus, Matthias Albrecht, Lorna J. Cole, Theodora Petanidou, Romualdas Zemeckis, David Kleijn, Miguel A. A. Pinheiro de Carvalho, Jean-Pierre Sarthou, Anželika Dautartė, Yael Mandelik, Montserrat Vilà, Robert J. Paxton, Hajnalka Szentgyörgyi, Nikolaos Emmanouil, Andrea Holzschuh, European Commission, Scotland's Rural College (SRUC), Wageningen University, University of East Anglia, Department of Zoology, University of Cambridge [UK] (CAM), Trinity College Dublin, University of Reading (UOR), Agroecology and Environment, Agroscope, Malta College of Arts, Science and Technology, Partenaires INRAE, Estación Biológica de Doñana (EBD), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Agricultural University of Athens, National Institute of Biology [Ljubljana] (NIB), Universiteit Leiden, Leiden University Center for Linguistics, Universiteit Leiden [Leiden]-Universiteit Leiden [Leiden], Slovak University of Agriculture, Vytautas Magnus University - Vytauto Didziojo Universitetas (VDU), Zambia National Farmers Union (ZNFU), The Game and Wildlife Conservation Trust, University of Würzburg, Naturalis Biodiversity Center [Leiden], MTA Centre for Ecological Research, The Hebreu University of Jerusalem, Martin-Luther-University Halle-Wittenberg, German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig, University of the Aegean, Universidade da Madeira (UMA), Department of Biology, Northern Arizona University [Flagstaff], AGroécologie, Innovations, teRritoires (AGIR), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Cyprus University of Technology, Instituto de Agricultura Sostenible - Institute for Sustainable Agriculture (IAS CSIC), Jagiellonian University, Abeilles et Environnement (AE), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Cole, Lorna J [0000-0002-3929-0530], Kleijn, David [0000-0003-2500-7164], Albrecht, Matthias [0000-0001-5518-3455], Bartomeus, Ignasi [0000-0001-7893-4389], Kovács-Hostyánszki, Anikó [0000-0001-5906-4816], Rundlöf, Maj [0000-0003-3014-1544], Szentgyörgyi, Hajnalka [0000-0002-5753-800X], Scheper, Jeroen [0000-0002-4314-996X], Apollo - University of Cambridge Repository, and Naturalis Biodiversity Center

Subjects
0106 biological sciences, Forage (honey bee), Resource (biology), Pollination, [SDE.MCG]Environmental Sciences/Global Changes, media_common.quotation_subject, pollinator conservation, Plant Ecology and Nature Conservation, 010603 evolutionary biology, 01 natural sciences, pollination services, CAP Green Architecture, Faculdade de Ciências da Vida, Scarcity, Pollinator, Pollination services, Pollinator conservation, Environmental planning, Research Articles, media_common, 2. Zero hunger, agri-environment schemes, habitat complementarity, Ecology, 010604 marine biology & hydrobiology, agri‐environment schemes, Environmental impact of agriculture, Expert elicitation, Biological Sciences, 15. Life on land, Bees, PE&RC, Ecological Focus Areas, Geography, Agri-environment schemes, 13. Climate action, Habitat complementarity, Plantenecologie en Natuurbeheer, bees, Natural Sciences, Common Agricultural Policy, Research Article
Abstract

Agricultural intensification and associated loss of high‐quality habitats are key drivers of insect pollinator declines. With the aim of decreasing the environmental impact of agriculture, the 2014 EU Common Agricultural Policy (CAP) defined a set of habitat and landscape features (Ecological Focus Areas: EFAs) farmers could select from as a requirement to receive basic farm payments. To inform the post‐2020 CAP, we performed a European‐scale evaluation to determine how different EFA options vary in their potential to support insect pollinators under standard and pollinator‐friendly management, as well as the extent of farmer uptake.A structured Delphi elicitation process engaged 22 experts from 18 European countries to evaluate EFAs options. By considering life cycle requirements of key pollinating taxa (i.e. bumble bees, solitary bees and hoverflies), each option was evaluated for its potential to provide forage, bee nesting sites and hoverfly larval resources.EFA options varied substantially in the resources they were perceived to provide and their effectiveness varied geographically and temporally. For example, field margins provide relatively good forage throughout the season in Southern and Eastern Europe but lacked early‐season forage in Northern and Western Europe. Under standard management, no single EFA option achieved high scores across resource categories and a scarcity of late season forage was perceived.Experts identified substantial opportunities to improve habitat quality by adopting pollinator‐friendly management. Improving management alone was, however, unlikely to ensure that all pollinator resource requirements were met. Our analyses suggest that a combination of poor management, differences in the inherent pollinator habitat quality and uptake bias towards catch crops and nitrogen‐fixing crops severely limit the potential of EFAs to support pollinators in European agricultural landscapes. Policy Implications. To conserve pollinators and help protect pollination services, our expert elicitation highlights the need to create a variety of interconnected, well‐managed habitats that complement each other in the resources they offer. To achieve this the Common Agricultural Policy post‐2020 should take a holistic view to implementation that integrates the different delivery vehicles aimed at protecting biodiversity (e.g. enhanced conditionality, eco‐schemes and agri‐environment and climate measures). To improve habitat quality we recommend an effective monitoring framework with target‐orientated indicators and to facilitate the spatial targeting of options collaboration between land managers should be incentivised., To conserve pollinators and help protect pollination services, our expert elicitation highlights the need to create a variety of interconnected, well‐managed habitats that complement each other in the resources they offer. To achieve this the Common Agricultural Policy post‐2020 should take a holistic view to implementation that integrates the different delivery vehicles aimed at protecting biodiversity (e.g. enhanced conditionality, eco‐schemes and agri‐environment and climate measures). To improve habitat quality we recommend an effective monitoring framework with target‐orientated indicators and to facilitate the spatial targeting of options collaboration between land managers should be incentivised.

Published
2020
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33. Food system integration of olive-oil producing small farms in Southern Europe

Author

Ana C. Fonseca, Francesca Galli, Laura Fastelli, Paolo Prosperi, Victor Martinez-Gomez, Elpiniki Oikonomopoulou, Giannis Goussios, Pavlos Karanikolas, Laura Arnalte-Mur, Maria Rivera, Paola A. Hernández, Agricultural University of Athens, Universitat Politècnica de València (UPV), Department of Agriculture - Food and Environment, University of Pisa, Montpellier Interdisciplinary center on Sustainable Agri-food systems (Social and nutritional sciences) (UMR MoISA), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Centre International de Hautes Etudes Agronomiques Méditerranéennes - Institut Agronomique Méditerranéen de Montpellier (CIHEAM-IAMM), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM), Instituto de Ciências Agrárias e Ambientais Mediterrânicas (ICAAM), University of Evora, University of Pisa - Università di Pisa, Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Centre International de Hautes Etudes Agronomiques Méditerranéennes - Institut Agronomique Méditerranéen de Montpellier (CIHEAM-IAMM), European Project: 677363,H2020,H2020-SFS-2015-2,SALSA(2016), and Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)

Subjects
Market integration, 10.- Reducir las desigualdades entre países y dentro de ellos, Southern Europe, 030309 nutrition & dietetics, 15.- Proteger, restaurar y promover la utilización sostenible de los ecosistemas terrestres, gestionar de manera sostenible los bosques, combatir la desertificación y detener y revertir la degradación de la tierra, y frenar la pérdida de diversidad biológica, Small farms, 03 medical and health sciences, 0502 economics and business, Localized food systems, Olive oil, Strategies, Safety, Risk, Reliability and Quality, Industrial organization, 2. Zero hunger, 0303 health sciences, Ecology, 05 social sciences, [SHS.ECO]Humanities and Social Sciences/Economics and Finance, Reciprocity (evolution), ECONOMIA, SOCIOLOGIA Y POLITICA AGRARIA, 02.- Poner fin al hambre, conseguir la seguridad alimentaria y una mejor nutrición, y promover la agricultura sostenible, 08.- Fomentar el crecimiento económico sostenido, inclusivo y sostenible, el empleo pleno y productivo, y el trabajo decente para todos, 12.- Garantizar las pautas de consumo y de producción sostenibles, 16.- Promover sociedades pacíficas e inclusivas para el desarrollo sostenible, facilitar acceso a la justicia para todos y crear instituciones eficaces, responsables e inclusivas a todos los niveles, small farm, strategies, Food systems, 050202 agricultural economics & policy, Business, Safety Research, Externality, Food Science
Abstract

[EN] This study aims to identify the various forms of integration of olive-oil-producing small farms (OSFs) into food systems in four Southern European regions, as well as to identify the most beneficial strategies of integration. Drawing on data from the SALSA Project, the study has found that besides self-provision, OSFs are engaged in multiple types of integration, including reciprocity relations as well as relations with informal and formal markets. Multiple strategies with synergistic effects co-exist at the farm/farm household level. However, specific territorial resources are partially mobilized by actors? strategies; consequently, olive oil identities are valorized on the market to some extent, but less so through positive externalities. Therefore, the unrealized potential of localization of food systems in which OSFs operate is identified., This study draws on material from the Project "SALSA" ("Small farms, small food businesses and sustainable food security"). This project has received funding from the European Union's Horizon 2020 research and innovation programme, under grant agreement No 677363

Published
2021
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35. AROMATIC PLANTS AS FEED FOR GOATS IN AURÈS MOUNTAINS OF ALGERIA: CHARACTERIZATION OF VOLATILE AND PHENOLIC COMPOUNDS

Author

Bouguerra, Ali, Cornu, Agnes, Zouaoui, Nassim, Djebili, Samah, El Hadef El Okki, Mohamed, Martin, Bruno, Massouras, Theophilos, Barkat, Malika, INATAA, Bioqual Laboratory, Université Mentouri Constantine [Algérie] (UMC), Unité Mixte de Recherche sur les Herbivores - UMR 1213 (UMRH), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), University of Tebessa, Department of Applied Biology, University of Mentouri Brothers, Agricultural University of Athens, Laboratory of Dairy Science and Technology, Department of Food Science and Technology, and Cornu, Agnès

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], feed, aromatic plants, Goat, phenolic compounds, volatile compounds
Abstract

International audience; The aim of this work was to make an inventory of the aromatic plants pastured by goats in theAurès Mountains of Algeria and to characterize their volatile and phenolic compounds. In this context, asurvey was conducted among goat farmers in this region (department of Batna). Plant volatile compoundswere analyzed using HS-SPME/GC-MS and phenolic compounds using HPLC-DAD. According to theresults of the survey, twenty-nine (29) aromatic plants were identified as goats’ feed. The most cited oneswere Thymus algeriensis (96 %), Artemisia herba alba Asso (91 %), Rosmarinus officinalis L. (83 %),Juniperus phoenica L. (80 %), Artemisia campestris L. (80 %), and Marrubium vulgare L. (70 %). Themajor volatile compounds were -pinene (40 %), -thujone (38 %), trans-caryophyllene (31 %), -myrcene(29 %), camphor (27 %), and -thujone (18 %). The most abundant phenolic compounds were flavonoids(rutin, kaempferol-3-O-rutinoside, apigenin, hesperidin, isoquercitrin, and quercitrin), cinnamic acidderivatives (chlorogenic acid, rosmarinic acid, caffeic acid, and ferulic acid), coumarines, and benzoic acidderivatives. The present results indicate that aromatic plants from Aurès mountains of Algeria are rich inphenolic compounds and could be offered as feed for goats.

Published
2021

36. Topical Application of Double-Stranded RNA Targeting 2b and CP Genes of Cucumber mosaic virus Protects Plants against Local and Systemic Viral Infection

Author

Mikhail Pooggin, Athanasios Sklavounos, Maria C. Holeva, Rajendran Rajeswaran, Andreas E. Voloudakis, Benaki Phytopathological Institute (BPI), Agricultural University of Athens, Hellenic Ministry of Rural Development and Food, Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich), Plant Health Institute of Montpellier (UMR PHIM), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Université de Montpellier (UM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), project PYTHAGORAS II (MIS 99832) funded by the General Secretariat of Research and Technology (GSRT) of Greece, and COST Action FA0806 'Plant virus control employing RNA-based vaccines: A novel non-transgenic strategy' funded by EU.

Subjects
0106 biological sciences, 0301 basic medicine, Small interfering RNA, [SDV]Life Sciences [q-bio], viruses, Plant Science, 01 natural sciences, dsRNA vaccination, Article, Cucumber mosaic virus, 03 medical and health sciences, RNA interference, Plant virus, Small interfering RNAs, Double-stranded RNA, Gene, Ecology, Evolution, Behavior and Systematics, Ecology, biology, fungi, Botany, RNA, food and beverages, Virology, RNAi, RNA silencing, 030104 developmental biology, QK1-989, biology.protein, 010606 plant biology & botany, Dicer
Abstract

Cucumber mosaic virus (CMV) is a destructive plant virus with worldwide distribution and the broadest host range of any known plant virus, as well as a model plant virus for understanding plant–virus interactions. Since the discovery of RNA interference (RNAi) as a major antiviral defense, RNAi-based technologies have been developed for plant protection against viral diseases. In plants and animals, a key trigger of RNAi is double-stranded RNA (dsRNA) processed by Dicer and Dicer-like (DCL) family proteins in small interfering RNAs (siRNAs). In the present study, dsRNAs for coat protein (CP) and 2b genes of CMV were produced in vitro and in vivo and applied onto tobacco plants representing a systemic solanaceous host as well as on a local host plant Chenopodium quinoa. Both dsRNA treatments protected plants from local and systemic infection with CMV, but not against infection with unrelated viruses, confirming sequence specificity of antiviral RNAi. Antiviral RNAi was effective when dsRNAs were applied simultaneously with or four days prior to CMV inoculation, but not four days post inoculation. In vivo-produced dsRNAs were more effective than the in vitro-produced; in treatments with in vivo dsRNAs, dsRNA-CP was more effective than dsRNA-2b, while the effects were opposite with in vitro dsRNAs. Illumina sequencing of small RNAs from in vivo dsRNA-CP treated and non-treated tobacco plants revealed that interference with CMV infection in systemic leaves coincides with strongly reduced accumulation of virus-derived 21- and 22-nucleotide (nt) siRNAs, likely generated by tobacco DCL4 and DCL2, respectively. While the 21-nt class of viral siRNAs was predominant in non-treated plants, 21-nt and 22-nt classes accumulated at almost equal (but low) levels in dsRNA treated plants, suggesting that dsRNA treatment may boost DCL2 activity. Taken together, our findings confirm the efficacy of topical application of dsRNA for plant protection against viruses and shed more light on the mechanism of antiviral RNAi., Plants, 10 (5), ISSN:2223-7747

Published
2021
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37. Adaptive business arrangements and the creation of social capital: Towards small‐scale fisheries resilience in different European geographical areas

Author

James Kirwan, Gianluca Brunori, Daniele Vergamini, Fabio Bartolini, Paolo Prosperi, Damian Maye, George Vlahos, Emi Tsakalou, Montpellier Interdisciplinary center on Sustainable Agri-food systems (Social and nutritional sciences) (UMR MoISA), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Centre International de Hautes Etudes Agronomiques Méditerranéennes - Institut Agronomique Méditerranéen de Montpellier (CIHEAM-IAMM), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), University of Pisa - Università di Pisa, Centre International de Hautes Etudes Agronomiques Méditerranéennes - Institut Agronomique Méditerranéen de Montpellier (CIHEAM-IAMM), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM), Countryside and Community Research Institute, University of Gloucestershire, Francis Close Hall Campus, Swindon Road, Cheltenham GL50 4AZ, UK, Agricultural University of Athens, Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara (DOCPAS), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Montpellier, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Università degli Studi di Ferrara = University of Ferrara (UniFE), European Project: 635577,H2020,H2020-SFS-2014-2,SUFISA(2015), and Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)

Subjects
0106 biological sciences, new business models, Sociology and Political Science, 010501 environmental sciences, 01 natural sciences, GRECE, Economica, UNITED KINGDOM, Social capital, Order (exchange), PECHE ARTISANALE, ITALIE, Primary producer, GB, primary producers, GE, DURABILITE, [SHS.ECO]Humanities and Social Sciences/Economics and Finance, GF, ARTISANAL FISHERIES, TRADE AGREEMENTS, Scale (social sciences), Sustainable management, ITALY, Small-scale fisheries resilience, EUROPE, ROYAUME UNI, Fishing, Socio-culturale, ACCORD COMMERCIAL, Competition (economics), SUSTAINABILITY, institutional arrangements, GREECE, G1, 14. Life underwater, SH, INSTITUTION, CAPITAL SOCIAL, Resilience (network), 0105 earth and related environmental sciences, 010604 marine biology & hydrobiology, Non- productivism, Ambientale, RESILIENCE, Fishery, New business model, non-productivism, Economic sustainability, Institutional arrangement, [SHS.ENVIR]Humanities and Social Sciences/Environmental studies, Business
Abstract

International audience; European small-scale fisheries are confronted with several challenges, notably a decrease in the number of people engaged in capture fishing, growing competition from less expensive extra-EU markets, rising operational costs, strict regulations and the depletion of fishing stocks. Many small-scale fishers must adapt to change to maintain or increase their income using different business strategies. In this respect, we argue that new and diversified institutional arrangements combined with building social capital can help reach long-term economic sustainability for small-scale fisheries businesses, as well as the social-ecological resilience of coastal areas. In order to understand and analyse the multiplicity of strategies applied by small-scale fishers – including expansion towards non–productivist activities – this paper examines the role of new institutional arrangements based on small-scale, traditional, quality-orientated, multifunctional business strategies, as well as non-fishing activities. Using a case study approach, we analyse – in three different European fishery contexts (Greece, Italy, and the UK respectively) – how the interplay between building adaptive arrangements and the creation of social capital in selected small-scale fisheries provides relevant prerequisites for resilience.

Published
2021
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38. Defining the Rhizobium leguminosarum Species Complex

Author

En Tao Wang, Aregu Amsalu Aserse, Raúl Rivas González, José David Flores Félix, Anastasia P. Tampakaki, Marta Maluk, Encarna Velázquez, Arvind Gulati, Stéphane Boivin, M. Harun-or Rashid, Marc Lepetit, Euan K. James, Chang Fu Tian, Sara Moeskjær, Beatriz Jorrin, Sameh H. Youseif, Alexey M. Afonin, Michael F. Hynes, Evgeny E. Andronov, Martha-Helena Ramírez-Bahena, Gregory Kenicer, Alvaro Peix, J. Peter W. Young, Praveen Rahi, Benjamin J. Perry, Maria Izabel A. Cavassim, Ecosystems and Environment Research Programme, European Commission, Velázquez, Encarna, Rivas, Raúl, Peix, Álvaro, Ramírez Bahena, M. Helena, University of York [York, UK], Aarhus University [Aarhus], All-Russia Research Institute for Agricultural Microbiology [Saint-Pétersbourg, Russie] (ARRIAM), Ctr Natl Rech Sci, Inst Biochim & Biophys Mol & Cellulaire, Unite Mixte Rech 8619, Université Paris-Sud - Paris 11 (UP11), The James Hutton Institute, University of California [Los Angeles] (UCLA), University of California (UC), Bangladesh Institute of Nuclear Agriculture, Helsingin yliopisto = Helsingfors universitet = University of Helsinki, University of Otago [Dunedin, Nouvelle-Zélande], Inst Politecn Nacl, CICATA, Queretaro 76090, Mexico, Instituto Politecnico Nacional [Mexico] (IPN), Universidad de Salamanca, Agricultural University of Athens, University of Beira Interior [Portugal] (UBI), International Center for Agricultural Research in the Dry Areas [Egypte] (ICARDA), International Center for Agricultural Research in the Dry Areas (ICARDA), Consultative Group on International Agricultural Research [CGIAR] (CGIAR)-Consultative Group on International Agricultural Research [CGIAR] (CGIAR), Institut Sophia Agrobiotech (ISA), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Côte d'Azur (UCA), Laboratoire des symbioses tropicales et méditerranéennes (UMR LSTM), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Université de Montpellier (UM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), University of Oxford, Royal Botanic Garden [Edinburgh], University of Calgary, Institute of Himalayan Bioresource Technology, China Agricultural University (CAU), ANR-16-CE20-0021,GRaSP,Caractérisation du déterminisme génétique du choix du partenaire symbiotique pour une amélioration de la symbiose fixatrice d'azote chez le pois(2016), European Project: 613551,EC:FP7:KBBE,FP7-KBBE-2013-7-single-stage,LEGATO(2014), Velázquez, Encarna [0000-0002-5946-7241], Rivas, Raúl [0000-0003-2202-1470], Peix, Álvaro [0000-0001-5084-1586], and Ramírez Bahena, M. Helena [0000-0002-0744-8313]

Subjects
0301 basic medicine, 0106 biological sciences, Species complex, housekeeping, lcsh:QH426-470, Genospecies, bacterial taxonomy, [SDV]Life Sciences [q-bio], Speciation, 030106 microbiology, housekeeping genes, macromolecular substances, Biology, medicine.disease_cause, 01 natural sciences, Genome, Rhizobium leguminosarum, 03 medical and health sciences, genospecies, Phylogenetics, Genetics, Core genes, medicine, biochemistry, core genes, genes, Clade, species complex, Gene, Genetics (clinical), 030304 developmental biology, 0303 health sciences, Housekeeping genes, 1184 Genetics, developmental biology, physiology, average nucleotide identity, Bacterial taxonomy, Average nucleotide identity, musculoskeletal system, Housekeeping gene, body regions, lcsh:Genetics, 030104 developmental biology, Sister group, speciation, Evolutionary biology, Rhizobium, 010606 plant biology & botany
Abstract

Bacteria currently included in Rhizobium leguminosarum are too diverse to be considered a single species, so we can refer to this as a species complex (the Rlc). We have found 429 publicly available genome sequences that fall within the Rlc and these show that the Rlc is a distinct entity, well separated from other species in the genus. Its sister taxon is R. anhuiense. We constructed a phylogeny based on concatenated sequences of 120 universal (core) genes, and calculated pairwise average nucleotide identity (ANI) between all genomes. From these analyses, we concluded that the Rlc includes 18 distinct genospecies, plus 7 unique strains that are not placed in these genospecies. Each genospecies is separated by a distinct gap in ANI values, usually at approximately 96% ANI, implying that it is a &lsquo, natural&rsquo, unit. Five of the genospecies include the type strains of named species: R. laguerreae, R. sophorae, R. ruizarguesonis, &ldquo, R. indicum&rdquo, and R. leguminosarum itself. The 16S ribosomal RNA sequence is remarkably diverse within the Rlc, but does not distinguish the genospecies. Partial sequences of housekeeping genes, which have frequently been used to characterize isolate collections, can mostly be assigned unambiguously to a genospecies, but alleles within a genospecies do not always form a clade, so single genes are not a reliable guide to the true phylogeny of the strains. We conclude that access to a large number of genome sequences is a powerful tool for characterizing the diversity of bacteria, and that taxonomic conclusions should be based on all available genome sequences, not just those of type strains.

Published
2021
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39. Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight

Author

Maryam Sharafkhah, Emanuel Zitt, Majid Ezzati, Luxia Zhang, Young-Ho Khang, Ellina Rakhimova, Kairit Mikkel, Tiina Vlasoff, Eruke E. Egbagbe, Sidsel Graff-Iversen, Ilona Nenko, Magdalena Klimek, Mathilde Savy, Sanjib Kumar Sharma, Alfonso Siani, Luís Lopes, Vanina Bongard, Gregor Jurak, Jacqueline F. Price, Christina-Paulina Lambrinou, Maria Lc Iurilli, Rainford J. Wilks, Bontha V. Babu, Fereidoun Azizi, Harunobu Nakamura, Marialaura Bonaccio, Angela Döring, Zhenyu Zhang, Naser Ahmadi, Jolanta Słowikowska-Hilczer, Ana Paula Carlos Cândido, Clive Osmond, Thirunavukkarasu Sathish, Robert J. Adams, Themistoklis Tzotzas, Reina Engle-Stone, Atul Trivedi, Shoichiro Tsugane, Niels Møller, Jorge Bezerra, Dénes Molnár, Muhammad Fadhli Mohd Yusoff, Badreya Al-Lahou, J. Jaime Miranda, Bahram Mohajer, Sigmund A. Anderssen, Lital Keinan Boker, Eero Kajantie, Martin Gulliford, Maties Torrent, Sumit Bharadwaj, Toshiharu Ninomiya, Zbigniew Gaciong, Nayu Ikeda, Li Juan Wu, Adrian Richter, Licia Iacoviello, Marc J. Gunter, Wenbin Wei, Norsyamlina Che Abdul Rahim, Eman Aly, Ambady Ramachandran, Nils Lehmann, Soile E. Puhakka, Giovanni Veronesi, Hongsheng Bi, Eiji Oda, Jia Li Duan, Per Tynelius, José María Huerta, Janne Schurmann Tolstrup, Rodrigo M. Carrillo-Larco, Rosangela Fernandes Lucena Batista, Victoria E Soto-Rojas, Hanno Ulmer, Shukri F. Mohamed, Anthony Kafatos, Suyeon Park, Mohsen Ibrahim, Hamed Pouraram, Bin Zhou, May Soe Aung, Lars Bo Andersen, Erfan Ghasemi, René Charles Sylva, Himanshu K. Chaturvedi, Luc Dauchet, Ahmad Ali Zainuddin, Angela Chetrit, Dan Zhu, Valérie Deschamps, Ko Ko Zaw, Peter Vollenweider, Tomas Vega, Yves Martin-Prével, Mahfuzar Rahman, Dorja Vočanec, Roman Topor-Madry, Vinay Nangia, Herculina S. Kruger, Asher Fawwad, Emily Sonestedt, Elena Pahomova, Aleksander Giwercman, Elżbieta Dziankowska-Zaborszczyk, Cecilia Björkelund, Tatjana Hejgaard, Maria Puiu, Maria Benedetta Donati, Andrew Wong, Carlos P. Boissonnet, Santosh K. Bhargava, Patrick Kolsteren, Dermot O'Reilly, Bahareh Kheiri, Wolfgang Kratzer, Susanne R. de Rooij, H. Bas Bueno-de-Mesquita, Günther Fink, José R. Banegas, Michele Monroy-Valle, Drude Molbo, Mahmudur Rahman, Hynek Pikhart, Rafael N. Pichardo, Massimo Salvetti, Hui Cai, Sarah Filippi, Georg Posch, Hung-Kwan So, Yonghua Hu, Katsuyasu Kouda, Joana Carvalho, Gailute Bernotiene, Hannu Uusitalo, Thein Thein Htay, Felix Kaducu, Maigeng Zhou, Lars Ängquist, Thi Tuyet-Hanh Tran, Charles Lunogelo, Michel Joffres, Sabina Zambon, Ronald D. Gregor, Vayia Rarra, Seyed Mohammad Hashemi-Shahri, Loreto Santa Marina, Galina Obreja, Rudolf Kaaks, Aya Mostafa, Maria do Carmo Franco, Beata Gurzkowska, Chien-Jen Chen, Marie Moitry, Nizal Sarrafzadegan, Xiangjun Wang, Diego Giulliano Destro Christofaro, Imperia Brajkovich, Fangfang Chen, Francesco Panza, Ling Yang, Holly E. Syddall, Cecily Kelleher, Michael Tornaritis, Ningli Wang, Lutgarde Thijs, Marjolein Visser, Angelika Schaffrath Rosario, María José Tormo, Jostein Steene-Johannessen, Norbert Amougou, Emmanuella Magriplis, Mar Alvarez-Pedrerol, Jingli Gao, Stig E. Bojesen, Giuseppe Grosso, Seongjun Ha, Lauren Lissner, Mikhail Benet, Anastasia Markaki, Sanjay Rampal, Antônio Augusto Moura da Silva, Maria Lorenza Muiesan, Angelique Chan, Yvonne T. van der Schouw, Annamari Lundqvist, Philippe Amouyel, Kristyna Zejglicova, Charalambos Hadjigeorgiou, João Breda, Jørgen Meisfjord, Fatima Zahra Laamiri, Carl Lachat, Kai-Uwe Saum, Vilma Irazola, Leng Huat Foo, Óscar Lopes, Dickman Gareta, Flavio Nervi, Imre Janszky, Ruzena Kubinova, Terho Lehtimäki, Mario V. Capanzana, Moyses Szklo, Ramfis Nieto-Martínez, Viswanathan Mohan, Shuohua Chen, Arvind Pandey, Luigi Palmieri, Roya Kelishadi, Srinivasan Kannan, Jie Mi, Robert Beaglehole, Liliana Dacica, Jyrki K. Virtanen, Mohan Deepa, Peter Ueda, Isti Ilmiati Fujiati, Hermann Pohlabeln, Morten Sodemann, Jytte Halkjær, Zbigniew Kułaga, Sophie Visvikis-Siest, Farshad Farzadfar, Mohsen Azimi-Nezhad, Henry Völzke, Karolina Milkowska, Zahra Mohammadi, Belgin Ünal, Magda Gasull, George S. Stergiou, Marshall K. Tulloch-Reid, Seppo Koskinen, James E. Bennett, Marcela González-Gross, Virginija Dulskiene, Idris Guessous, Assembekov Batyrbek, Kamarul Imran Musa, Jeannette Lee, Josep Redon, Bihungum Bista, Luisa M Macieira, Johan Sundström, Andres Metspalu, Lariane M Ono, Flora A. Ukoli, Salar Rahimikazerooni, Andrea Gualtieri, Trevor S. Ferguson, Félicité Tchibindat, Eliza Cinteza, Ha Tp Do, Tajana Zeljkovic Vrkic, Tuyen D Le, Alison J. Hayes, Abdul Basit, Chandini Nekkantti, Teresa Norat, Eunice Ugel, Gulmira Aitmurzaeva, Mariachiara Di Cesare, Abdul Hamid Zargar, Vincenzo Solfrizzi, Garry L. Jennings, Aline Meirhaeghe, Kaare Christensen, Päivi Mäki, Xu Lin, Ali Esmaeili, Joanna Baran, Aneta Grajda, Renata Cifkova, Alexandre C. Pereira, Martin Bobak, Iuliia A Rusakova, Keiu Nelis, Damian K Francis, Guansheng Ma, Axel C. Carlsson, Alejandro Diaz, Alireza Ansari-Moghaddam, N Capkova, Zumin Shi, Maria Turley, Imelda A. Agdeppa, Helena I. S. Nogueira, Marcia Scazufca, Katharina Maruszczak, Natascia Rinaldo, Paulo A. Lotufo, Nuno Lunet, Thor Aspelund, Caroline H.D. Fall, Antonio Cabrera de León, Ahmad Faudzi Yusoff, Holger Theobald, Beatriz D'Agord Schaan, Pedro Marques-Vidal, William A. Neal, Mihai Gafencu, Tandi E. Matsha, Ana B. Crujeiras, Ahmad Reza Dorosty, Alain Morejon, Weili Yan, Dominique Hange, Bekbolat Zholdin, Frédéric Gottrand, Jorge Mota, Jana Námešná, Stevo Popovic, Louise Eriksen, Line Lund Kårhus, Cihangir Erem, Juergen Breckenkamp, Mathilde Kersting, Yi Song, Martin McKee, Aleksandra Gomula, Rafaela Rosário, Enzo Manzato, S. Goya Wannamethee, Sounnia Mediene Benchekor, Azim Nejatizadeh, Krishna Kumar Aryal, Juan P. González-Rivas, Vedrana Sember, Stephen T. McGarvey, Jukka T. Salonen, Patrick Pasquet, Patricia Varona-Pérez, Amelia C. Crampin, Ramin Heshmat, Violeta Iotova, Juvenal Soares Dias-da-Costa, Oye Gureje, Aletta E. Schutte, João Luiz Bastos, Anelise Reis Gaya, Konrad Jamrozik, Dalia Luksiene, Amina Barkat, Maria Paula Santos, José Camolas, Azli Baharudin, Diego Vanuzzo, Doris Stöckl, Rosalynn Siantar, Jouko Saramies, Albertino Damasceno, Davood Khalili, Simona Bo, Martina Müller-Nurasyid, Dominique Cottel, Markku Peltonen, Fikru Tullu, Ana Isabel Rito, Angélica Ochoa-Avilés, Annette J. Dobson, Christopher T. Cowell, Charumathi Sabanayagam, Rildo de Souza Wanderley Júnior, Oanh T. H. Trinh, Farahnaz Joukar, Mostafa K. Mohamed, Mostafa Qorbani, Jeongseon Kim, Helmut Schröder, Machi Suka, Natasja M. van Schoor, Jussi Kauhanen, Teresa Haugsgjerd, Goodarz Danaei, M. Fernanda Lima-Costa, Yong Tao, Elisabetta L. Romeo, Grazyna Jasienska, Victor Guillermo Sequera, Kazem Mohammad, Yanina Zócalo, Fernanda Cunha Soares, Jianfeng Wu, Mohammad Esmaeel Motlagh, María Elena Díaz-Sánchez, Monika Zuziak, Eldridge Ferrer, Anette Varbo, Leila Beltrami Moreira, Jeremy M. Jacobs, Kenneth James, Elena Sacchini, Pascal Bovet, Mahboubeh Parsaeian, Tania Lopez, Ya Xing Wang, Wojciech Drygas, Jody C Miller, Svetlana A. Shalnova, Maria Elisa Zapata, Chung T Nguyen, Nimmathota Arlappa, Edwige Landais, Thorkild I. A. Sørensen, Jeannette Klimont, Amirabbas Momenan, Erik J. Timmermans, Mari-Liis Tammesoo, Jost B. Jonas, Stefania Toselli, Maria Teresa Anselmo Olinto, Bahman Cheraghian, Kouamelan Doua, Esteban Carmuega, Marjeta Mišigoj-Duraković, Bo Werner, M. Arfan Ikram, Breige A. McNulty, Christa Meisinger, Clara Homs, Namuna Shrestha, Alina Kerimkulova, Youcef Laid, Claes Ohlsson, Alicia Matijasevich, Alison J Price, Ala'a Alkerwi, Kristine H. Allin, Lorenza Pilotto, Mohannad Al Nsour, Ingunn Holden Bergh, Marianna Noale, Heba Fouad, Vilnis Dzerve, Novie O. Younger-Coleman, Peter Willeit, Andrea R. V. R. Horimoto, Freda Pitakaka, Habiba Ben Romdhane, Savvas C. Savva, Rajeev Gupta, Jennifer Servais, Cristina Padez, Sarah P. Garnett, Maria del Cristo Rodriguez-Perez, Michala Lustigová, Tien Yin Wong, Rosa Haghshenas, Jonathan Giovannelli, Christina Howitt, Marleen E. Hendriks, Fadia AlBuhairan, Huashuai Chen, Gretchen A Stevens, Luís B. Sardinha, David Goltzman, Jenny M. Kindblom, Karina Mary de Paiva, Yousef Khader, Eric Monterrubio-Flores, Rajendra Pradeepa, Yi-Ting Lin, Martin Neovius, Juan Francisco Miquel, Ellis Owusu-Dabo, Anil Poudyal, Marzieh Katibeh, Tanja Stocks, Veronica Mocanu, Ulla Roggenbuck, Robespierre Ribeiro, Gabriele Eiben, Mary Simon, Christine Cameron, Hamid Hakimi, Kamel Ajlouni, Jakub Stokwiszewski, Iulia Jurca Simina, Pietro Amedeo Modesti, Frederick C. W. Wu, Peter Kristensen, Charles Mondo, Felix Gutzwiller, Mariana Sbaraini, Martijn Huisman, Betina H. Thuesen, Queenie Chan, Antonisamy Belavendra, Artur Mazur, Ulf Ekelund, Laura A. Rodríguez-Villamizar, Marcos André Moura-dos-Santos, Jean Ferrières, Farhad Zamani, Shina Avi, Yves Kameli, Luis Paulo Gomes Mascarenhas, Aluísio J D Barros, Thomas Meinertz Dantoft, Hossein Poustchi, Farid Najafi, Giovanni de Gaetano, Azaliia M Tuliakova, Vera Lanska, Tint Swe Latt, Matthias Bopp, Abbas Rezaianzadeh, Rod Jackson, Johan Van der Heyden, Reecha Sofat, Koen Van Herck, Allan G. Hill, Con Burns, Emanuela Pettenuzzo, Ming-Dong Wang, Stela McLachlan, Ulrike Gehring, Ranko Stevanovic, Nagalla Balakrishna, Lekhraj Rampal, Marjolijn C. E. Bragt, Saeid Eslami, Napoleón Pérez-Farinós, G. K. Mini, Viktoria Anna Kovacs, Rosemarie Martin, Nahla Hwalla, Wei Zheng, Hoang Van Minh, Edward D Janus, Laetitia Huiart, Farhad Pourfarzi, Sudha Ramachandra Rao, Fred Paccaud, Marcia Makdisse, Aye Aye Sein, Enrique Gutiérrez-González, Yang Yang, Anneke Blokstra, Henrike Galenkamp, Jaume Marrugat, Nazan Yardim, Wan Nazaimoon Wan Mohamud, Jesús Ibarluzea, Julio Zuñiga Cisneros, Laura Lauria, Argyro Karakosta, Dragana P Jovic, Jun Hata, Elio Riboli, Piotr Bandosz, Xun Tang, Parvina Mukhtorova, Jean Dallongeville, Jean-Bernard Ruidavets, Anne Tjønneland, Guillermo Frontera, Rahul Malhotra, Thomas Ferrao, Aleksandra Piwońska, Dusan Grafnetter, Mette Rasmussen, Daniel Weghuber, Sherali Rakhmatulloev, Martine Vrijheid, Johann Willeit, Motahareh Kheradmand, Małgorzata Mossakowska, Lechaba Tshepo, Dongfeng Gu, Hyeon Chang Kim, Vilmundur Gudnason, Maria Forsner, Peter Bjerregaard, Leon A. Simons, Rachael McLean, Japhet Killewo, Ramón Suárez-Medina, Y Nikitin, Eng Joo Tan, Jean Claude Mbanya, Aroor Bhagyalaxmi, Renata Kuciene, Kairat Davletov, Jose Eugenio Lozano, Afshin Ostovar, Niloofar Peykari, Guy De Backer, Soheir H Ahmed, Nicholas J. Wareham, Sai Yin Ho, Constanta Huidumac Petrescu, Maria Hassapidou, Iris Pigeot, Myriam Galfo, Susana Cararo Confortin, Blanca Sandra Ruiz-Betancourt, W. M. Monique Verschuren, Catterina Ferreccio, Fabio Galvano, Leila Houti, Daniel Bia, Annika Rosengren, Marcin Rutkowski, Biruta Velika, Joana Araújo, Fernando Rigo, Angela Spinelli, Scott B. McLean, Shirin Djalalinia, Marie Kunešová, Boban Mugoša, Sania Nishtar, Mangesh S. Pednekar, Shahla AlDhukair, Helle-Mai Loit, Antonis Zampelas, Altan Onat, Maciej Banach, Shohreh Naderimagham, Hajer Aounallah-Skhiri, Maja Bæksgaard Jørgensen, Yin Guo, Ewelina Czenczek-Lewandowska, Parasmani Dasgupta, Elvis Oa Wambiya, Inge Huybrechts, Raimund Erbel, Jari Jokelainen, Ana P. Ortiz, Stefan Kiechl, Emmanuel Cohen, Caleb Ochimana, Shynar Abdrakhmanova, Laura Censi, Iqbal Bata, Geetha R Menon, Snehalatha Chamukuttan, Pedro Plans-Rubio, Domenico Palli, Ana Azevedo, Slawomir Koziel, Benoît Salanave, Parinaz Mehdipour, Shu Ti Chiou, Lela Sturua, Lubica Ticha, Felipe Vogt Cureau, Jin Soo Moon, Ming-Hui Zhao, Urho M. Kujala, Nathalie Michels, Ertugrul Celikcan, Jaakko Tuomilehto, Judith Benedics, Tobias F. Rinke de Wit, Agnès Le Port, Reza Homayounfar, Andrea Rodriguez-Martinez, Tai Hing Lam, Yn-Tz Sung, Jürgen König, Kodavanti Mallikharjuna Rao, Hazzaa M. Al-Hazzaa, Karen Morgan, Bogdan Wojtyniak, Cynthia M. Pérez, Ilse Khouw, Manoli Garcia-de-la-Hera, Dong Wook Shin, Genc Burazeri, Ausra Petrauskiene, Charles Sossa Jérome, Kenisha Russell Jonsson, José Boggia, Daniela Galeone, Alice Bonilla-Vargas, Han Cg Kemper, Rahman Shiri, Stefaan Demarest, Else Karin Grøholt, San-Lin You, Adelheid Weber, Juha Auvinen, Aida Pilav, Sibel Gogen, Suzanne N Morin, Wan Mohamad Wan Bebakar, Viviane Cunha Cardoso, Kavumpurathu Raman Thankappan, Hana Zamrazilová, Frank Claessens, Karien Stronks, Helen Gonçalves, Tahir Aris, Luis Revilla, Sérgio Viana Peixoto, Zhamilya Battakova, Jing Liu, Eliza Markidou Ioannidou, Leticia Hernandez Cadena, Priscilla Duboz, Sandjaja, Tiina Laatikainen, Rafel Ramos, Sareh Eghtesad, Judith Simons, Orn Olafsson, E. Shyong Tai, Louise A. Baur, Nihal Thomas, Aung Soe Htet, Bente Sparboe-Nilsen, Paul Elliott, Soon-Woo Park, Angel R. Gonzalez, Ying-Wei Wang, Rob M. van Dam, Ryutaro Ohtsuka, Ludmila Sevcikova, Suhaila Abdul Ghaffar, Lynell V Maniego, Fariborz Mansour-Ghanaei, Maria Dorobantu, Giovanni Viegi, Xiaoguang Yang, Honor Bixby, Prakash C. Gupta, Ofra Kalter-Leibovici, Eugene Sobngwi, Ričardas Radišauskas, Jurate Medzioniene, Roy A Wong-McClure, Kim F. Michaelsen, Antonia Trichopoulou, Tania Tello, Francesco Branca, Johanna Gunnlaugsdottir, Els Clays, Wei-Yen Lim, Suzanne C. Ho, Toomas Veidebaum, Rebecca Goldsmith, Margot González-León, Matthias Nauck, Alibek Mereke, Marta Buoncristiano, Jakob Tarp, Rosalba Rojas-Martínez, Maya Tanrygulyyeva, Reza Malekzadeh, Abdonas Tamosiunas, Dimitrios Poulimeneas, Pedro Ordunez, Isabelle Herter-Aeberli, Khanh Le Nguyen Bao, Anne Juolevi, Vassilis Zafiropulos, Emanuela Gualdi-Russo, Jordi Sunyer, Manu Raj, Chaoqiang Jiang, Sofia Malyutina, Efthymios Kapantais, Maria Lazo-Porras, Maung Maung Than Htike, Michael Hobbs, Ranjit Mohan Anjana, Merike Liivak, Johan G. Eriksson, Margarita Samoutian, Andreia N. Pizarro, Mohammed Rasoul Tarawneh, Jean Woo, Kaspar Staub, Maria Teresa Menzano, Mojtaba Farjam, Adroaldo Cesar Araujo Gaya, Mohammad El-khateeb, Zulfiqar A Bhutta, Mukharram M. Bikbov, Hsien-Ho Lin, Oscar Noboa, Thomas Waldhör, Garry Brian, Simona Costanzo, Frank Tanser, Nor Azwany Yaacob, Michelle Cilia, Ivo Rakovac, Bill Stavreski, Ioannis Pagkalos, Ivan Pećin, Carlo M. Barbagallo, Abla M. Sibai, Yuna He, Matsuda Fumihiko, Bharathi Viswanathan, Ali Reza Safarpour, Wei Cheng Lo, Abdullatif Husseini, Jiang He, Liv Elin Torheim, Nipa Rojroongwasinkul, Aicha Soumare, Astrid Petersmann, Tomasz Grodzicki, Davide Noto, Panayiotis K. Yiallouros, Kelias P. Msyamboza, William R. Tebar, Yingfeng Zheng, Eha Nurk, Bhawesh Koirala, Ana Jelakovic, Suhad Bahijri, Freja B Kampmann, Qi Sheng You, Marika Ferrari, María-Elena González-Villalpando, Aline Wagner, Olfa Saidi, Anwar Batieha, Eduardo Capuano, Coimbatore Subramaniam Shanthirani, Dong Wook Kim, Albina A Fakhretdinova, Tom Wilsgaard, Maria Avdicova, Moesijanti Soekatri, Chiara Donfrancesco, Salim Mohanna, Paola Russo, Uruwan Yamborisut, Rafael dos Santos Henrique, Martin Nankap, Allan Linneberg, Khairil Si-Ramlee, Kirsten Mehlig, Christina Mavrogianni, Raluca Pop, Lèlita Santos, Graziella Bruno, Valentina Peterkova, Iná S. Santos, Georg Lappas, Alberto Palloni, Malay K. Mridha, Andrzej Pajak, Marta García-Solano, Stefaan De Henauw, Daniel Ferrante, Rute Santos, Anders Grøntved, Lucjan Szponar, Mihaela Vladulescu, Chien-An Sun, Jan A. Staessen, Paula Duarte de Oliveira, Norazizah Ibrahim Wong, Maria Nordendahl, Elaine M. Dennison, Jeonghee Lee, Diego Salmerón, Ida Maria Schmidt, Gao Pei, Noushin Mohammadifard, Igor Spiroski, Fernando Rodríguez-Artalejo, Xu Ma, Elin Pettersen Sørgjerd, Valéria Regecová, Cláudia S. Minderico, Johanna A. Otero, Jamila Abubakar Garba, Vesselka Duleva, Rui Ornelas, Ilpo Huhtaniemi, Cesar G. Victora, Lijuan Liu, Rody G. Sy, Mahmood Moosazadeh, Ali Ahmadi, Antonio Pedro Graça, Natalia Nowak-Szczepanska, Miao Li Chee, Michael Sjöström, Charles Agyemang, Shiqi Zhen, Xiu-Hua Guo, Pawel Kurjata, Jardena J. Puder, Mehrdad Azmin, Neil Murphy, Kaosar Afsana, Alireza Sadjadi, Johanna M. Geleijnse, Prashant Mathur, Elysée Claude Bika Lele, Raphael Mendes Ritti-Dias, Yannis Manios, Majid Shirani, Rosemary B. Duda, Liis Nelis, Jurate Klumbiene, Zhengming Chen, Wichai Aekplakorn, Alun Evans, Andrzej Wiecek, Lars Lind, Denise Eldemire-Shearer, Bernardo L. Horta, Macia Enguerran, Seyed Rasoul Zakavi, Daniel Fernández-Bergés, Kumiko Ohara, Ursula Kiechl-Kohlendorfer, Hermann Brenner, Przemyslaw Slusarczyk, Espen Bjertness, Jutta Stieber, Augusto Di Castelnuovo, Joel G. R. Roy, Aryeh D. Stein, Ruth Frikke-Schmidt, Vera Musil, Amaneh Shayanrad, Marcel Goldberg, Ramon O. Jimenez, Mohammad Reza Fattahi, Jolanda Hyska, Amir Houshang Mehrparvar, Elin Kolle, Mohamed Bamoshmoosh, Michelle Holdsworth, Felipe F. Casanueva, Børge G. Nordestgaard, Niels Wedderkopp, Eva Corpeleijn, Elias F. Gudmundsson, Antonio Mistretta, Daniel Lemogoum, Larissa Pruner Marques, Slavica Sović, Olli T. Raitakari, Marco Aurélio Peres, Alexandra Cucu, Gregorio Varela-Moreiras, Janine Clarke, Andrea Gazzinelli, Mieczysław Litwin, Sara Schramm, Xenophon Theodoridis, Harshpal Singh Sachdev, Mohammad Reza Mirjalili, Dimitrios Papandreou, Peter T. Katzmarzyk, Benjamin Acosta-Cazares, Ben Schöttker, Prabhdeep Kaur, Norlaila Mustafa, Shariq Rashid Masoodi, Sadaf G. Sepanlou, Adolfo Rubinstein, Francis Delpeuch, Julianne Williams, Abbas Dehghan, Leanne M. Riley, Heloisa Bettiol, Gabriele Nagel, Ellisiv B. Mathiesen, Ekaterina Stoyanova, Alisha N. Wade, Zhamyila Usupova, Arnaud Chiolero, Oonagh Markey, Jacqueline Ramke, Elena Bogova, Niveen M E Abu-Rmeileh, Nguyen D Nguyen, Tomasz Zdrojewski, Marjo-Riitta Järvelin, Jose Sanchez-Abanto, Rômulo Araújo Fernandes, Lourdes Ribas-Barba, Nalan Uysal, Mohamad Hasnan Ahmad, Krista Fischer, Maria Wany Louzada Strufaldi, Ramiro Guerrero, Farnam Mohebi, Tran Quoc Bao, Flávio Danni Fuchs, Salim Berkinbayev, Enisa Kujundzic, Sari Voutilainen, Farzad Hadaegh, Robert Lundqvist, Saeid Safiri, Iraj Mohebbi, George Luiz Lins Machado-Coelho, Annette Peters, Gonzalo Valdivia, Magdalena Korzycka, Rajiv T Erasmus, Masanori Iwasaki, Charmaine A. Duante, Sheikh Mohammed Shariful Islam, Quang Ngoc La, Ricky Eddie, Petra Rust, Daniela Rodrigues, Dirk De Bacquer, Karen Sparrenberger, Agneta Sjöberg, Thet Thet Mu, Katarzyna Dereń, Cora L. Craig, Jorge Motta, Janina Petkeviciene, Boyd Swinburn, Paibul Suriyawongpaisal, Visnja Djordjic, Ramón Alberto Rascón-Pacheco, Pradeep Joshi, Daan Kromhout, Marius B. Bjertness, Stefano Marventano, Juel Jarani, Alireza Khosravi, Eva Martos, David De Ridder, Lizzy M. Brewster, Nico Dragano, Liam Smeeth, Kenji Shibuya, Emma Ruiz Moreno, Hashem Jaddou, Grzegorz Sobek, Dimitrios Trichopoulos, Marvin Cervantes-Loaiza, Abu Am Hanif, Elaine M. Murtagh, Carlos A. Aguilar-Salinas, Graziella D'Arrigo, Kyungwon Oh, Heiner Boeing, Regina Heidinger-Felso, André Luiz Sena Guimarães, Balkish M. Naidu, Avula Laxmaiah, Ana M. B. Menezes, Marie Eliasen, Francesco Pistelli, Yuan He, Dusko Bjelica, José A. Casajús, Guang Ning, Lutgart Braeckman, Dirk Vanderschueren, Jochanan Stessman, Ivana Radic, Yi Zeng, Hans Concin, Damaskini Valvi, Sari Hantunen, Catherine Kyobutungi, Diego Augusto Santos Silva, Wenhua Zhao, Sok King Ong, Anne W. Taylor, Iraj Nabipour, Justyna Godos, Cyrus Cooper, Mattias Johansson, Samuel C. Dumith, Magdalena Muc, Sabine Schipf, Idowu O Senbanjo, Jim Mann, Rajaa Al-Raddadi, Yih Chung Tham, Kay-Tee Khaw, Joseph Cacciottolo, Ana Henriques, Sahar Saeedi Moghaddam, Reza Mohammadpourhodki, Bernhard O. Boehm, Songhomitra Panda-Jonas, Iveta Pudule, Elisabete Ramos, Lacramioara Aurelia Brinduse, Paul H. Lee, Terence W O'Neill, Javad Aghazadeh-Attari, Margus Punab, Bojan Jelaković, Camilla T. Damsgaard, Takafumi Ishida, Ekaterina Chikova-Iscener, Mirjam M. Heinen, Tazeen H. Jafar, Semánová Csilla, Constance Schultsz, Santiago F. Gomez, Raija Korpelainen, Edward W. Gregg, Laura Gutierrez, Pierre Traissac, Victor M. Herrera, Aristides M. Machado-Rodrigues, Fatemeh Malekzadeh, Shouling Wu, Jennifer L. Baker, Clicerio González-Villalpando, Eleonora d'Orsi, Irene G. M. van Valkengoed, Anna Fijałkowska, Wen-Harn Pan, Gregor Starc, Meghnath Dhimal, Murat Topbaş, George Moschonis, Robert Eggertsen, Abdullah Alkandari, Quang Ngoc Nguyen, Janette Walton, Elnaz Faramarzi, Saeed Dastgiri, Lien Braeckevelt, Nasheeta Peer, Radka Taxová Braunerová, Mohamed M. Ali, Steiner Krokstad, Harald Geiger, Morteza Shamshirgaran, Lela Shengelia, María Ángeles Dal Re Saavedra, Silvana Donoso, Khem Bahadur Karki, Timothy J. Key, Maria G. Grammatikopoulou, Susana Vale, Felix K. Assah, Juan A Rivera, Peter H. Whincup, Oana-Florentina Gheorghe-Fronea, Cassiano Ricardo Rech, Paul Ferdinand M. Reganit, Rachakulla Hari Kumar, Jaakko Mursu, Luis A. Moreno, Glen Gironella, Jelena Kos, Tilema Cama, Haakon E. Meyer, Jun Ma, Raphael E. Arku, Ziad Abdeen, Dianna J. Magliano, Jitendra Jonnagaddala, Konstantinos Gkiouras, Paola Nardone, Alberto Barceló, Tomi-Pekka Tuomainen, Francesco Gianfagna, Stefania Maggi, Mohammad Hossein Somi, Behrooz Hamzeh, Miquel Porta, Vesna Jureša, Alexander D. Deev, David Faeh, Antonio Bernabe-Ortiz, Sirkka Keinänen-Kiukaanniemi, Ian Hambleton, Stefan Savin, Andre Pascal Kengne, R. Krishna Kumar, Kurt Widhalm, Marco M Ferrario, Parisa Amiri, Anjani Kumar Jha, Thamara Hubler Figueiró, Jana Kratenova, Claudia M. Hormiga, Maria Tsigga, Zivka Dika, Indrapal I. Meshram, Ei Ei K. Nang, Ian Rouse, Rusidah Selamat, Paul Korrovits, Grethe S. Tell, Julie Taylor, Anabela Mota-Pinto, Paolo Vineis, Kotsedi D Monyeki, Khuong Quynh Long, Frank J Rühli, Shelly R. McFarlane, Sara Santos Sanz, Edyta Łuszczki, Maria G. Stathopoulou, Tara Coppinger, Karin De Ridder, Lucie Viet, Anna Bugge, Mehdi Yaseri, Safiah Md Yusof, Sandra C. Fuchs, Muhammad Islam, Irfan Nuhoglu, Rui Providência, Bernard Maire, Leandra Abarca-Gómez, Sinead Brophy, Maria Ruiz-Castell, Daniela Pierannunzio, Cristina Taddei, Gowri Mahasampath, Gustavo Velasquez-Melendez, Hanna Tolonen, Sudhir Kowlessur, Bagher Larijani, Laura Torres-Collado, Susi Kriemler, Ali Akbar Shayesteh, Cynthia Robitaille, Jorge Escobedo-de la Peña, Yufang Bi, Chinh Nguyen Huu, Line Tang Møllehave, Vincent Jr DeGennaro, Noor Ani Ahmad, Anar Dushpanova, Agustinus Soemantri, Susana Sans, Ionela Pascanu, Gwenaëlle Le Coroller, Inger Ariansen, Kodanda R Kanala, Gert B. M. Mensink, Abhijit Sen, Sergej M. Ostojic, Hanan F. Abdul Rahim, Hélène Delisle, Francisco J. Félix-Redondo, Yadlapalli S. Kusuma, Michael Knoflach, Moein Yoosefi, Tanja G. M. Vrijkotte, Wolfgang Ahrens, Osvaldo Santos, Bethlehem D. Solomon, Erik Lykke Mortensen, Nikhil D. Patel, Reynaldo Martorell, Ching-Yu Cheng, Stine Schramm, Hana Shimizu-Furusawa, Jacek Jóźwiak, Radwan Qasrawi, Herman Borghs, Zhanna Kalmatayeva, Heidi Klakk, Akram Pourshams, Naomi S. Levitt, Son Thai Pham, Simona Giampaoli, Dong Zhao, Indah Suci Widyahening, Merete Osler, Paula Margozzini, Silvia Bel-Serrat, Dora Romaguera, Monira Alarouj, Winsome R. Parnell, Marloes Cardol, Giota Touloumi, Janice Luisa Lukrafka, Adela Chirita-Emandi, Maryam Kavousi, Sanja Musić Milanović, Jean-Michel Gaspoz, Jalila El Ati, Sauli Herrala, Liang Xu, Pilar Guallar-Castillón, Bee Koon Poh, Luis Serra-Majem, Jonathan E. Shaw, Belong Cho, Daphne Mirkopoulou, Salvador Villalpando, Yuki Fujita, Tiffany K. Gill, Nish Chaturvedi, Erkin M. Mirrakhimov, Günay Can, Mark Woodward, Esther Lopez-Garcia, Mauro Virgílio Gomes de Barros, Ahmed A. Madar, Shoaib Afzal, Melanie J. Cowan, Gareth Stratton, Eduardo Salazar Martinez, Sameer Narake, Norie Sawada, Deepak Amarapurkar, Deepa Weerasekera, Diana A. 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Chan School of Public Health, Middlesex University [London], Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), Montpellier Interdisciplinary center on Sustainable Agri-food systems (Social and nutritional sciences) (UMR MoISA), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Centre International de Hautes Etudes Agronomiques Méditerranéennes - Institut Agronomique Méditerranéen de Montpellier (CIHEAM-IAMM), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Interactions Gène-Environnement en Physiopathologie Cardio-Vasculaire (IGE-PCV), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Wellcome TrustEuropean Commission, Clinical Developmental Psychology, APH - Mental Health, Sociology, The Social Context of Aging (SoCA), Nutrition and Health, Iurilli, Maria LC [0000-0003-0409-1635], Zhou, Bin [0000-0002-1741-8628], Ezzati, Majid [0000-0002-2109-8081], Apollo - University of Cambridge Repository, Epidemiology and Data Science, APH - Aging & Later Life, APH - Societal Participation & Health, Public and occupational health, APH - Health Behaviors & Chronic Diseases, VU University medical center, APH 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Ltd, Orebro University, University of London, Universitas Indonesia, Institute of Food and Nutrition Development of Ministry of Agriculture and Rural Affairs, Children’s Hospital of Fudan University, University of Cyprus, Niigata University, International Medical University, Iran University of Medical Sciences, Center for Diabetes and Endocrine Care, Peking University First Hospital, Jiangsu Provincial Center for Disease Control and Prevention, Sun Yat-sen University, West Kazakhstan Medical University, Inner Mongolia Medical University, University of Ghana, Maria Lc Iurilli , Bin Zhou , James E Bennett , Rodrigo M Carrillo-Larco , Marisa K Sophiea , Andrea Rodriguez-Martinez , Honor Bixby , Bethlehem D Solomon , Cristina Taddei , Goodarz Danaei , Mariachiara Di Cesare , Gretchen A Stevens , Leanne M Riley , Stefan Savin , Melanie J Cowan , Pascal Bovet , Albertino Damasceno , Adela Chirita-Emandi , Alison J Hayes , Nayu Ikeda , Rod T Jackson , Young-Ho Khang , Avula Laxmaiah , Jing 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Lind , Allan Linneberg , Lauren Lissner , Mieczyslaw Litwin , Lijuan Liu , Wei-Cheng Lo , Helle-Mai Loit , Khuong Quynh Long , Luis Lopes , Oscar Lopes , Esther Lopez-Garcia , Tania Lopez , Paulo A Lotufo , José Eugenio Lozano , Janice L Lukrafka , Dalia Luksiene , Annamari Lundqvist , Robert Lundqvist , Nuno Lunet , Charles Lunogelo , Michala Lustigová , Edyta Łuszczki , Guansheng Ma , Jun Ma , Xu Ma , George Ll Machado-Coelho , Aristides M Machado-Rodrigues , Luisa M Macieira , Ahmed A Madar , Stefania Maggi , Dianna J Magliano , Sara Magnacca , Emmanuella Magriplis , Gowri Mahasampath , Bernard Maire , Marjeta Majer , Marcia Makdisse , Päivi Mäki , Fatemeh Malekzadeh , Reza Malekzadeh , Rahul Malhotra , Kodavanti Mallikharjuna Rao , Sofia K Malyutina , Lynell V Maniego , Yannis Manios , Jim I Mann , Fariborz Mansour-Ghanaei , Enzo Manzato , Paula Margozzini , Anastasia Markaki , Oonagh Markey , Eliza Markidou Ioannidou , Pedro Marques-Vidal , Larissa Pruner Marques , Jaume Marrugat 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Benjamin, Adams, Robert J, Aekplakorn, Wichai, Afsana, Kaosar, Afzal, Shoaib, Agdeppa, Imelda A, Aghazadeh-Attari, Javad, Aguilar-Salinas, Carlos A, Agyemang, Charle, Ahmad, Mohamad Hasnan, Ahmad, Noor Ani, Ahmadi, Ali, Ahmadi, Naser, Ahmed, Soheir H, Ahrens, Wolfgang, Aitmurzaeva, Gulmira, Ajlouni, Kamel, Al-Hazzaa, Hazzaa M, Al-Lahou, Badreya, Al-Raddadi, Rajaa, Alarouj, Monira, AlBuhairan, Fadia, AlDhukair, Shahla, Ali, Mohamed M, Alkandari, Abdullah, Alkerwi, Ala'a, Allin, Kristine, Alvarez-Pedrerol, Mar, Aly, Eman, Amarapurkar, Deepak N, Amiri, Parisa, Amougou, Norbert, Amouyel, Philippe, Bo Andersen, Lar, Anderssen, Sigmund A, Ängquist, Lar, Anjana, Ranjit Mohan, Ansari-Moghaddam, Alireza, Aounallah-Skhiri, Hajer, Araújo, Joana, Ariansen, Inger, Aris, Tahir, Arku, Raphael E, Arlappa, Nimmathota, Aryal, Krishna K, Aspelund, Thor, Assah, Felix K, Assunção, Maria Cecília F, Aung, May Soe, Auvinen, Juha, Avdicová, Mária, Avi, Shina, Azevedo, Ana, Azimi-Nezhad, Mohsen, Azizi, Fereidoun, Azmin, Mehrdad, Babu, Bontha V, Jørgensen, Maja Bæksgaard, Baharudin, Azli, Bahijri, Suhad, Baker, Jennifer L, Balakrishna, Nagalla, Bamoshmoosh, Mohamed, Banach, Maciej, Bandosz, Piotr, Banegas, José R, Baran, Joanna, Barbagallo, Carlo M, Barceló, Alberto, Barkat, Amina, Barros, Aluisio JD, Barros, Mauro Virgílio Gome, Basit, Abdul, Bastos, Joao Luiz D, Bata, Iqbal, Batieha, Anwar M, Batista, Rosangela L, Battakova, Zhamilya, Batyrbek, Assembekov, Baur, Louise A, Beaglehole, Robert, Bel-Serrat, Silvia, Belavendra, Antonisamy, Romdhane, Habiba Ben, Benedics, Judith, Benet, Mikhail, Bergh, Ingunn Holden, Berkinbayev, Salim, Bernabe-Ortiz, Antonio, Bernotiene, Gailute, Bettiol, Heloísa, Bezerra, Jorge, Bhagyalaxmi, Aroor, Bharadwaj, Sumit, Bhargava, Santosh K, Bhutta, Zulfiqar A, Bi, Hongsheng, Bi, Yufang, Bia, Daniel, Lele, Elysée Claude Bika, Bikbov, Mukharram M, Bista, Bihungum, Bjelica, Dusko J, Bjerregaard, Peter, Bjertness, Espen, Bjertness, Marius B, Björkelund, 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Censi, Laura, Cervantes-Loaiza, Marvin, Cesar, Juraci A, Chamukuttan, Snehalatha, Chan, Angelique W, Chan, Queenie, Chaturvedi, Himanshu K, Chaturvedi, Nish, Rahim, Norsyamlina Che Abdul, Li Chee, Miao, Chen, Chien-Jen, Chen, Fangfang, Chen, Huashuai, Chen, Shuohua, Chen, Zhengming, Cheng, Ching-Yu, Cheraghian, Bahman, Chetrit, Angela, Chikova-Iscener, Ekaterina, Chiolero, Arnaud, Chiou, Shu-Ti, Chirlaque, María-Dolore, Cho, Belong, Christensen, Kaare, Christofaro, Diego G, Chudek, Jerzy, Cifkova, Renata, Cilia, Michelle, Cinteza, Eliza, Claessens, Frank, Clarke, Janine, Clays, El, Cohen, Emmanuel, Concin, Han, Confortin, Susana C, Cooper, Cyru, Coppinger, Tara C, Corpeleijn, Eva, Costanzo, Simona, Cottel, Dominique, Cowell, Chri, Craig, Cora L, Crampin, Amelia C, Crujeiras, Ana B, Csilla, Semánová, Cucu, Alexandra M, Cui, Liufu, Cureau, Felipe V, Czenczek-Lewandowska, Ewelina, D'Arrigo, Graziella, d'Orsi, Eleonora, Dacica, Liliana, Re Saavedra, María Ángeles Dal, Dallongeville, Jean, 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Anar, Dzerve, Vilni, Dziankowska-Zaborszczyk, Elzbieta, Eddie, Ricky, Eftekhar, Ebrahim, Egbagbe, Eruke E, Eggertsen, Robert, Eghtesad, Sareh, Eiben, Gabriele, Ekelund, Ulf, El-Khateeb, Mohammad, El Ati, Jalila, Eldemire-Shearer, Denise, Eliasen, Marie, Elliott, Paul, Engle-Stone, Reina, Enguerran, Macia, Erasmus, Rajiv T, Erbel, Raimund, Erem, Cihangir, Eriksen, Louise, Eriksson, Johan G, la Peña, Jorge Escobedo-de, Eslami, Saeid, Esmaeili, Ali, Evans, Alun, Faeh, David, Fakhretdinova, Albina A, Fall, Caroline H, Faramarzi, Elnaz, Farjam, Mojtaba, Sant'Angelo, Victoria Farrugia, Farzadfar, Farshad, Fattahi, Mohammad Reza, Fawwad, Asher, Felix-Redondo, Francisco J, Ferguson, Trevor S, Fernandes, Romulo A, Fernández-Bergés, Daniel, Ferrante, Daniel, Ferrao, Thoma, Ferrari, Marika, Ferrario, Marco M, Ferreccio, Catterina, Ferrer, Eldridge, Ferrieres, Jean, Figueiró, Thamara Hubler, Fijalkowska, Anna, Fink, Günther, Fischer, Krista, Foo, Leng Huat, Forsner, Maria, Fouad, Heba M, Francis, Damian K, do Carmo Franco, Maria, Frikke-Schmidt, Ruth, Frontera, Guillermo, Fuchs, Flavio D, Fuchs, Sandra C, Fujiati, Isti I, Fujita, Yuki, Fumihiko, Matsuda, Furusawa, Takuro, Gaciong, Zbigniew, Gafencu, Mihai, Galbarczyk, Andrzej, Galenkamp, Henrike, Galeone, Daniela, Galfo, Myriam, Galvano, Fabio, Gao, Jingli, Garcia-de-la-Hera, Manoli, García-Solano, Marta, Gareta, Dickman, Garnett, Sarah P, Gaspoz, Jean-Michel, Gasull, Magda, Gaya, Adroaldo Cesar Araujo, Gaya, Anelise Rei, Gazzinelli, Andrea, Gehring, Ulrike, Geiger, Harald, Geleijnse, Johanna M, Ghanbari, Ali, Ghasemi, Erfan, Gheorghe-Fronea, Oana-Florentina, Giampaoli, Simona, Gianfagna, Francesco, Gill, Tiffany K, Giovannelli, Jonathan, Gironella, Glen, Giwercman, Aleksander, Gkiouras, Konstantino, Godos, Justyna, Gogen, Sibel, Goldberg, Marcel, Goldsmith, Rebecca A, Goltzman, David, Gómez, Santiago F, Gomula, Aleksandra, da Silva, Bruna Goncalves Cordeiro, Gonçalves, Helen, Gonzalez-Chica, David A, Gonzalez-Gross, Marcela, González-Leon, Margot, González-Rivas, Juan P, González-Villalpando, Clicerio, González-Villalpando, María-Elena, Gonzalez, Angel R, Gottrand, Frederic, Graça, Antonio Pedro, Graff-Iversen, Sidsel, Grafnetter, Dušan, Grajda, Aneta, Grammatikopoulou, Maria G, Gregor, Ronald D, Grodzicki, Tomasz, Grøholt, Else Karin, Grøntved, Ander, Grosso, Giuseppe, Gruden, Gabriella, Gu, Dongfeng, Gualdi-Russo, Emanuela, Guallar-Castillón, Pilar, Gualtieri, Andrea, Gudmundsson, Elias F, Gudnason, Vilmundur, Guerrero, Ramiro, Guessous, Idri, Guimaraes, Andre L, Gulliford, Martin C, Gunnlaugsdottir, Johanna, Gunter, Marc J, Guo, Xiu-Hua, Guo, Yin, Gupta, Prakash C, Gupta, Rajeev, Gureje, Oye, Gurzkowska, Beata, Gutiérrez-González, Enrique, Gutierrez, Laura, Gutzwiller, Felix, Ha, Seongjun, Hadaegh, Farzad, Hadjigeorgiou, Charalambos A, Haghshenas, Rosa, Hakimi, Hamid, Halkjær, Jytte, Hambleton, Ian R, Hamzeh, Behrooz, Hange, Dominique, Hanif, Abu AM, Hantunen, Sari, Hao, Jie, Kumar, Rachakulla Hari, Hashemi-Shahri, Seyed Mohammad, Hassapidou, Maria, Hata, Jun, Haugsgjerd, Teresa, He, Jiang, He, Yuan, He, Yuna, Heidinger-Felso, Regina, Heinen, Mirjam, Hejgaard, Tatjana, Hendriks, Marleen Elisabeth, dos Santos Henrique, Rafael, Henriques, Ana, Cadena, Leticia Hernandez, Herrala, Sauli, Herrera, Victor M, Herter-Aeberli, Isabelle, Heshmat, Ramin, Hill, Allan G, Ho, Sai Yin, Ho, Suzanne C, Hobbs, Michael, Holdsworth, Michelle, Homayounfar, Reza, Homs, Clara, Hopman, Wilma M, Horimoto, Andrea RVR, Hormiga, Claudia M, Horta, Bernardo L, Houti, Leila, Howitt, Christina, Htay, Thein Thein, Htet, Aung Soe, Htike, Maung Maung Than, Hu, Yonghua, Huerta, José María, Huhtaniemi, Ilpo Tapani, Huiart, Laetitia, Petrescu, Constanta Huidumac, Huisman, Martijn, Husseini, Abdullatif, Huu, Chinh Nguyen, Huybrechts, Inge, Hwalla, Nahla, Hyska, Jolanda, Iacoviello, Licia, Ibarluzea, Jesús M, Ibrahim, Mohsen M, Wong, Norazizah Ibrahim, Ikram, M Arfan, Iotova, Violeta, Irazola, Vilma E, Ishida, Takafumi, Islam, Muhammad, Islam, Sheikh Mohammed Shariful, Iwasaki, Masanori, Jacobs, Jeremy M, Jaddou, Hashem Y, Jafar, Tazeen, James, Kenneth, Jamil, Kazi M, Jamrozik, Konrad, Janszky, Imre, Janus, Edward, Jarani, Juel, Jarvelin, Marjo-Riitta, Jasienska, Grazyna, Jelakovic, Ana, Jelakovic, Bojan, Jennings, Garry, Jha, Anjani Kumar, Jiang, Chao Qiang, Jimenez, Ramon O, Jöckel, Karl-Heinz, Joffres, Michel, Johansson, Mattia, Jokelainen, Jari J, Jonas, Jost B, Jonnagaddala, Jitendra, Jørgensen, Torben, Joshi, Pradeep, Joukar, Farahnaz, Jovic, Dragana P, Jóźwiak, Jacek J, Juolevi, Anne, Jurak, Gregor, Simina, Iulia Jurca, Juresa, Vesna, Kaaks, Rudolf, Kaducu, Felix O, Kafatos, Anthony, Kajantie, Eero O, Kalmatayeva, Zhanna, Kalter-Leibovici, Ofra, Kameli, Yve, Kampmann, Freja B, Kanala, Kodanda R, Kannan, Srinivasan, Kapantais, Efthymio, Karakosta, Argyro, Kårhus, Line L, Karki, Khem B, Katibeh, Marzieh, Katz, Joanne, Katzmarzyk, Peter T, Kauhanen, Jussi, Kaur, Prabhdeep, Kavousi, Maryam, Kazakbaeva, Gyulli M, Keil, Ulrich, Boker, Lital Keinan, Keinänen-Kiukaanniemi, Sirkka, Kelishadi, Roya, Kelleher, Cecily, Kemper, Han CG, Kengne, Andre P, Keramati, Maryam, Kerimkulova, Alina, Kersting, Mathilde, Key, Timothy, Khader, Yousef Saleh, Khalili, Davood, Khaw, Kay-Tee, Kheiri, Bahareh, Kheradmand, Motahareh, Khosravi, Alireza, Khouw, Ilse MSL, Kiechl-Kohlendorfer, Ursula, Kiechl, Stefan, Killewo, Japhet, Kim, Dong Wook, Kim, Hyeon Chang, Kim, Jeongseon, Kindblom, Jenny M, Klakk, Heidi, Klimek, Magdalena, Klimont, Jeannette, Klumbiene, Jurate, Knoflach, Michael, Koirala, Bhawesh, Kolle, Elin, Kolsteren, Patrick, König, Jürgen, Korpelainen, Raija, Korrovits, Paul, Korzycka, Magdalena, Kos, Jelena, Koskinen, Seppo, Kouda, Katsuyasu, Kovacs, Viktoria A, Kowlessur, Sudhir, Koziel, Slawomir, Kratenova, Jana, Kratzer, Wolfgang, Kriemler, Susi, Kristensen, Peter Lund, Krokstad, Steiner, Kromhout, Daan, Kruger, Herculina S, Kubinova, Ruzena, Kuciene, Renata, Kujala, Urho M, Kujundzic, Enisa, Kulaga, Zbigniew, Kumar, R Krishna, Kunešová, Marie, Kurjata, Pawel, Kusuma, Yadlapalli S, Kuulasmaa, Kari, Kyobutungi, Catherine, La, Quang Ngoc, Laamiri, Fatima Zahra, Laatikainen, Tiina, Lachat, Carl, Laid, Youcef, Lam, Tai Hing, Lambrinou, Christina-Paulina, Landais, Edwige, Lanska, Vera, Lappas, Georg, Larijani, Bagher, Latt, Tint Swe, Lauria, Laura, Lazo-Porras, Maria, Le Coroller, Gwenaëlle, Le Nguyen Bao, Khanh, Le Port, Agnè, Le, Tuyen D, Lee, Jeannette, Lee, Jeonghee, Lee, Paul H, Lehmann, Nil, Lehtimäki, Terho, Lemogoum, Daniel, Levitt, Naomi S, Li, Yanping, Liivak, Merike, Lilly, Christa L, Lim, Wei-Yen, Lima-Costa, M Fernanda, Lin, Hsien-Ho, Lin, Xu, Lin, Yi-Ting, Lind, Lar, Linneberg, Allan, Lissner, Lauren, Litwin, Mieczyslaw, Liu, Lijuan, Lo, Wei-Cheng, Loit, Helle-Mai, Long, Khuong Quynh, Lopes, Lui, Lopes, Oscar, Lopez-Garcia, Esther, Lopez, Tania, Lotufo, Paulo A, Lozano, José Eugenio, Lukrafka, Janice L, Luksiene, Dalia, Lundqvist, Annamari, Lundqvist, Robert, Lunet, Nuno, Lunogelo, Charle, Lustigová, Michala, Łuszczki, Edyta, Ma, Guansheng, Ma, Jun, Ma, Xu, Machado-Coelho, George LL, Machado-Rodrigues, Aristides M, Macieira, Luisa M, Madar, Ahmed A, Maggi, Stefania, Magliano, Dianna J, Magnacca, Sara, Magriplis, Emmanuella, Mahasampath, Gowri, Maire, Bernard, Majer, Marjeta, Makdisse, Marcia, Mäki, Päivi, Malekzadeh, Fatemeh, Malekzadeh, Reza, Malhotra, Rahul, Rao, Kodavanti Mallikharjuna, Malyutina, Sofia K, Maniego, Lynell V, Manios, Yanni, Mann, Jim I, Mansour-Ghanaei, Fariborz, Manzato, Enzo, Margozzini, Paula, Markaki, Anastasia, Markey, Oonagh, Ioannidou, Eliza Markidou, Marques-Vidal, Pedro, Marques, Larissa Pruner, Marrugat, Jaume, Martin-Prevel, Yve, Martin, Rosemarie, Martorell, Reynaldo, Martos, Eva, Maruszczak, Katharina, Marventano, Stefano, Mascarenhas, Luis P, Masoodi, Shariq R, Mathiesen, Ellisiv B, Mathur, Prashant, Matijasevich, Alicia, Matsha, Tandi E, Mavrogianni, Christina, Mazur, Artur, Mbanya, Jean Claude N, McFarlane, Shelly R, McGarvey, Stephen T, McKee, Martin, McLachlan, Stela, McLean, Rachael M, McLean, Scott B, McNulty, Breige A, Benchekor, Sounnia Mediene, Medzioniene, Jurate, Mehdipour, Parinaz, Mehlig, Kirsten, Mehrparvar, Amir Houshang, Meirhaeghe, Aline, Meisfjord, Jørgen, Meisinger, Christa, Menezes, Ana Maria B, Menon, Geetha R, Mensink, Gert BM, Menzano, Maria Teresa, Mereke, Alibek, Meshram, Indrapal I, Metspalu, Andre, Meyer, Haakon E, Mi, Jie, Michaelsen, Kim F, Michels, Nathalie, Mikkel, Kairit, Milkowska, Karolina, Miller, Jody C, Minderico, Cláudia S, Mini, GK, Miquel, Juan Francisco, Mirjalili, Mohammad Reza, Mirkopoulou, Daphne, Mirrakhimov, Erkin, Mišigoj-Durakovic, Marjeta, Mistretta, Antonio, Mocanu, Veronica, Modesti, Pietro A, Moghaddam, Sahar Saeedi, Mohajer, Bahram, Mohamed, Mostafa K, Mohamed, Shukri F, Mohammad, Kazem, Mohammadi, Zahra, Mohammadifard, Noushin, Mohammadpourhodki, Reza, Mohan, Viswanathan, Mohanna, Salim, Yusoff, Muhammad Fadhli Mohd, Mohebbi, Iraj, Mohebi, Farnam, Moitry, Marie, Molbo, Drude, Møllehave, Line T, Møller, Niels C, Molnár, Déne, Momenan, Amirabba, Mondo, Charles K, Monroy-Valle, Michele, Monterrubio-Flores, Eric, Monyeki, Kotsedi Daniel K, Moon, Jin Soo, Moosazadeh, Mahmood, Moreira, Leila B, Morejon, Alain, Moreno, Luis A, Morgan, Karen, Morin, Suzanne N, Mortensen, Erik Lykke, Moschonis, George, Mossakowska, Malgorzata, Mostafa, Aya, Mota-Pinto, Anabela, Mota, Jorge, Motlagh, Mohammad Esmaeel, Motta, Jorge, Moura-dos-Santos, Marcos André, Mridha, Malay K, Msyamboza, Kelias P, Mu, Thet Thet, Muc, Magdalena, Mugoša, Boban, Muiesan, Maria L, Mukhtorova, Parvina, Müller-Nurasyid, Martina, Murphy, Neil, Mursu, Jaakko, Murtagh, Elaine M, Musa, Kamarul Imran, Milanovic, Sanja Music, Musil, Vera, Mustafa, Norlaila, Nabipour, Iraj, Naderimagham, Shohreh, Nagel, Gabriele, Naidu, Balkish M, Najafi, Farid, Nakamura, Harunobu, Námešná, Jana, Ei K Nang, Ei, Nangia, Vinay B, Nankap, Martin, Narake, Sameer, Nardone, Paola, Nauck, Matthia, Neal, William A, Nejatizadeh, Azim, Nekkantti, Chandini, Nelis, Keiu, Nelis, Lii, Nenko, Ilona, Neovius, Martin, Nervi, Flavio, Nguyen, Chung T, Nguyen, Nguyen D, Nguyen, Quang Ngoc, Nieto-Martínez, Ramfis E, Nikitin, Yury P, Ning, Guang, Ninomiya, Toshiharu, Nishtar, Sania, Noale, Marianna, Noboa, Oscar A, Nogueira, Helena, Norat, Teresa, Nordendahl, Maria, Nordestgaard, Børge G, Noto, Davide, Nowak-Szczepanska, Natalia, Al Nsour, Mohannad, Nuhoglu, Irfan, Nurk, Eha, O'Neill, Terence W, O'Reilly, Dermot, Obreja, Galina, Ochimana, Caleb, Ochoa-Avilés, Angélica M, Oda, Eiji, Oh, Kyungwon, Ohara, Kumiko, Ohlsson, Clae, Ohtsuka, Ryutaro, Olafsson, Örn, Olinto, Maria Teresa A, Oliveira, Isabel O, Omar, Mohd Azahadi, Onat, Altan, Ong, Sok King, Ono, Lariane M, Ordunez, Pedro, Ornelas, Rui, Ortiz, Ana P, Ortiz, Pedro J, Osler, Merete, Osmond, Clive, Ostojic, Sergej M, Ostovar, Afshin, Otero, Johanna A, Overvad, Kim, Owusu-Dabo, Elli, Paccaud, Fred Michel, Padez, Cristina, Pagkalos, Ioanni, Pahomova, Elena, de Paiva, Karina Mary, Pajak, Andrzej, Palli, Domenico, Palloni, Alberto, Palmieri, Luigi, Pan, Wen-Harn, Panda-Jonas, Songhomitra, Pandey, Arvind, Panza, Francesco, Papandreou, Dimitrio, Park, Soon-Woo, Park, Suyeon, Parnell, Winsome R, Parsaeian, Mahboubeh, Pascanu, Ionela M, Pasquet, Patrick, Patel, Nikhil D, Pecin, Ivan, Pednekar, Mangesh S, Peer, Nasheeta, Pei, Gao, Peixoto, Sergio Viana, Peltonen, Markku, Pereira, Alexandre C, Peres, Marco A, Pérez-Farinós, Napoleón, Pérez, Cynthia M, Peterkova, Valentina, Peters, Annette, Petersmann, Astrid, Petkeviciene, Janina, Petrauskiene, Ausra, Pettenuzzo, Emanuela, Peykari, Niloofar, Pham, Son Thai, Pichardo, Rafael N, Pierannunzio, Daniela, Pigeot, Iri, Pikhart, Hynek, Pilav, Aida, Pilotto, Lorenza, Pistelli, Francesco, Pitakaka, Freda, Piwonska, Aleksandra, Pizarro, Andreia N, Plans-Rubió, Pedro, Poh, Bee Koon, Pohlabeln, Hermann, Pop, Raluca M, Popovic, Stevo R, Porta, Miquel, Posch, Georg, Poudyal, Anil, Poulimeneas, Dimitrio, Pouraram, Hamed, Pourfarzi, Farhad, Pourshams, Akram, Poustchi, Hossein, Pradeepa, Rajendra, Price, Alison J, Price, Jacqueline F, Providencia, Rui, Puder, Jardena J, Pudule, Iveta, Puhakka, Soile E, Puiu, Maria, Punab, Margu, Qasrawi, Radwan F, Qorbani, Mostafa, Bao, Tran Quoc, Radic, Ivana, Radisauskas, Ricarda, Rahimikazerooni, Salar, Rahman, Mahfuzar, Rahman, Mahmudur, Raitakari, Olli, Raj, Manu, Rakhimova, Ellina, Rakhmatulloev, Sherali, Rakovac, Ivo, Rao, Sudha Ramachandra, Ramachandran, Ambady, Ramke, Jacqueline, Ramos, Elisabete, Ramos, Rafel, Rampal, Lekhraj, Rampal, Sanjay, Rarra, Vayia, Rascon-Pacheco, Ramon A, Rasmussen, Mette, Rech, Cassiano Ricardo, Redon, Josep, Reganit, Paul Ferdinand M, Regecová, Valéria, Revilla, Lui, Rezaianzadeh, Abba, Ribas-Barba, Lourde, Ribeiro, Robespierre, Riboli, Elio, Richter, Adrian, Rigo, Fernando, Rinaldo, Natascia, de Wit, Tobias F Rinke, Rito, Ana, Ritti-Dias, Raphael M, Rivera, Juan A, Robitaille, Cynthia, Roccaldo, Romana, Rodrigues, Daniela, Rodríguez-Artalejo, Fernando, del Cristo Rodriguez-Perez, María, Rodríguez-Villamizar, Laura A, Roggenbuck, Ulla, Rojas-Martinez, Rosalba, Rojroongwasinkul, Nipa, Romaguera, Dora, Romeo, Elisabetta L, Rosario, Rafaela V, Rosengren, Annika, Rouse, Ian, Roy, Joel GR, Rubinstein, Adolfo, Rühli, Frank J, Ruidavets, Jean-Bernard, Ruiz-Betancourt, Blanca Sandra, Ruiz-Castell, Maria, Moreno, Emma Ruiz, Rusakova, Iuliia A, Jonsson, Kenisha Russell, Russo, Paola, Rust, Petra, Rutkowski, Marcin, Sabanayagam, Charumathi, Sacchini, Elena, Sachdev, Harshpal S, Sadjadi, Alireza, Safarpour, Ali Reza, Safiri, Saeid, Saki, Nader, Salanave, Benoit, Martinez, Eduardo Salazar, Salmerón, Diego, Salomaa, Veikko, Salonen, Jukka T, Salvetti, Massimo, Samoutian, Margarita, Sánchez-Abanto, Jose, Sandjaja, null, Sans, Susana, Marina, Loreto Santa, Santos, Diana A, Santos, Ina S, Santos, Lèlita C, Santos, Maria Paula, Santos, Osvaldo, Santos, Rute, Sanz, Sara Santo, Saramies, Jouko L, Sardinha, Luis B, Sarrafzadegan, Nizal, Sathish, Thirunavukkarasu, Saum, Kai-Uwe, Savva, Savva, Savy, Mathilde, Sawada, Norie, Sbaraini, Mariana, Scazufca, Marcia, Schaan, Beatriz D, Rosario, Angelika Schaffrath, Schargrodsky, Herman, Schienkiewitz, Anja, Schipf, Sabine, Schmidt, Carsten O, Schmidt, Ida Maria, Schnohr, Peter, Schöttker, Ben, Schramm, Sara, Schramm, Stine, Schröder, Helmut, Schultsz, Constance, Schutte, Aletta E, Sein, Aye Aye, Selamat, Rusidah, Sember, Vedrana, Sen, Abhijit, Senbanjo, Idowu O, Sepanlou, Sadaf G, Sequera, Victor, Serra-Majem, Lui, Servais, Jennifer, Ševcíková, Ludmila, Shalnova, Svetlana A, Shamah-Levy, Teresa, Shamshirgaran, Morteza, Shanthirani, Coimbatore Subramaniam, Sharafkhah, Maryam, Sharma, Sanjib K, Shaw, Jonathan E, Shayanrad, Amaneh, Shayesteh, Ali Akbar, Shengelia, Lela, Shi, Zumin, Shibuya, Kenji, Shimizu-Furusawa, Hana, Shin, Dong Wook, Shirani, Majid, Shiri, Rahman, Shrestha, Namuna, Si-Ramlee, Khairil, Siani, Alfonso, Siantar, Rosalynn, Sibai, Abla M, Silva, Antonio M, Silva, Diego Augusto Santo, Simon, Mary, Simons, Judith, Simons, Leon A, Sjöberg, Agneta, Sjöström, Michael, Skodje, Gry, Slowikowska-Hilczer, Jolanta, Slusarczyk, Przemyslaw, Smeeth, Liam, So, Hung-Kwan, Soares, Fernanda Cunha, Sobek, Grzegorz, Sobngwi, Eugène, Sodemann, Morten, Söderberg, Stefan, Soekatri, Moesijanti YE, Soemantri, Agustinu, Sofat, Reecha, Solfrizzi, Vincenzo, Somi, Mohammad Hossein, Sonestedt, Emily, Song, Yi, Sørensen, Thorkild IA, Sørgjerd, Elin P, Jérome, Charles Sossa, Soto-Rojas, Victoria E, Soumaré, Aïcha, Sovic, Slavica, Sparboe-Nilsen, Bente, Sparrenberger, Karen, Spinelli, Angela, Spiroski, Igor, Staessen, Jan A, Stamm, Hanspeter, Stathopoulou, Maria G, Staub, Kaspar, Stavreski, Bill, Steene-Johannessen, Jostein, Stehle, Peter, Stein, Aryeh D, Stergiou, George S, Stessman, Jochanan, Stevanovic, Ranko, Stieber, Jutta, Stöckl, Dori, Stocks, Tanja, Stokwiszewski, Jakub, Stoyanova, Ekaterina, Stratton, Gareth, Stronks, Karien, Strufaldi, Maria Wany, Sturua, Lela, Suárez-Medina, Ramón, Suka, Machi, Sun, Chien-An, Sundström, Johan, Sung, Yn-Tz, Sunyer, Jordi, Suriyawongpaisal, Paibul, Swinburn, Boyd A, Sy, Rody G, Syddall, Holly E, Sylva, René Charle, Szklo, Moyse, Szponar, Lucjan, Tai, E Shyong, Tammesoo, Mari-Lii, Tamosiunas, Abdona, Tan, Eng Joo, Tang, Xun, Tanrygulyyeva, Maya, Tanser, Frank, Tao, Yong, Tarawneh, Mohammed Rasoul, Tarp, Jakob, Tarqui-Mamani, Carolina B, Braunerová, Radka Taxová, Taylor, Anne, Taylor, Julie, Tchibindat, Félicité, Tebar, William R, Tell, Grethe S, Tello, Tania, Tham, Yih Chung, Thankappan, KR, Theobald, Holger, Theodoridis, Xenophon, Thijs, Lutgarde, Thomas, Nihal, Thuesen, Betina H, Tichá, Lubica, Timmermans, Erik J, Tjonneland, Anne, Tolonen, Hanna K, Tolstrup, Janne S, Topbas, Murat, Topór-Madry, Roman, Torheim, Liv Elin, Tormo, María José, Tornaritis, Michael J, Torrent, Matie, Torres-Collado, Laura, Toselli, Stefania, Touloumi, Giota, Traissac, Pierre, Tran, Thi Tuyet-Hanh, Trichopoulos, Dimitrio, Trichopoulou, Antonia, Trinh, Oanh TH, Trivedi, Atul, Tshepo, Lechaba, Tsigga, Maria, Tsugane, Shoichiro, Tuliakova, Azaliia M, Tulloch-Reid, Marshall K, Tullu, Fikru, Tuomainen, Tomi-Pekka, Tuomilehto, Jaakko, Turley, Maria L, Twig, Gilad, Tynelius, Per, Tzotzas, Themistokli, Tzourio, Christophe, Ueda, Peter, Ugel, Eunice, Ukoli, Flora AM, Ulmer, Hanno, Unal, Belgin, Usupova, Zhamyila, Uusitalo, Hannu MT, Uysal, Nalan, Vaitkeviciute, Justina, Valdivia, Gonzalo, Vale, Susana, Valvi, Damaskini, van Dam, Rob M, Van der Heyden, Johan, van der Schouw, Yvonne T, Van Herck, Koen, Van Minh, Hoang, Van Schoor, Natasja M, van Valkengoed, Irene GM, Vanderschueren, Dirk, Vanuzzo, Diego, Varbo, Anette, Varela-Moreiras, Gregorio, Varona-Pérez, Patricia, Vasan, Senthil K, Vega, Toma, Veidebaum, Tooma, Velasquez-Melendez, Gustavo, Velika, Biruta, Veronesi, Giovanni, Verschuren, WM Monique, Victora, Cesar G, Viegi, Giovanni, Viet, Lucie, Villalpando, Salvador, Vineis, Paolo, Vioque, Jesu, Virtanen, Jyrki K, Visser, Marjolein, Visvikis-Siest, Sophie, Viswanathan, Bharathi, Vladulescu, Mihaela, Vlasoff, Tiina, Vocanec, Dorja, Vollenweider, Peter, Völzke, Henry, Voutilainen, Ari, Voutilainen, Sari, Vrijheid, Martine, Vrijkotte, Tanja GM, Wade, Alisha N, Wagner, Aline, Waldhör, Thoma, Walton, Janette, Wambiya, Elvis OA, Bebakar, Wan Mohamad Wan, Mohamud, Wan Nazaimoon Wan, de Souza Wanderley Júnior, Rildo, Wang, Ming-Dong, Wang, Ningli, Wang, Qian, Wang, Xiangjun, Wang, Ya Xing, Wang, Ying-Wei, Wannamethee, S Goya, Wareham, Nichola, Weber, Adelheid, Wedderkopp, Niel, Weerasekera, Deepa, Weghuber, Daniel, Wei, Wenbin, Weres, Aneta, Werner, Bo, Whincup, Peter H, Widhalm, Kurt, Widyahening, Indah S, Wiecek, Andrzej, Wilks, Rainford J, Willeit, Johann, Willeit, Peter, Williams, Julianne, Wilsgaard, Tom, Wojtyniak, Bogdan, Wong-McClure, Roy A, Wong, Andrew, Wong, Jyh Eiin, Wong, Tien Yin, Woo, Jean, Woodward, Mark, Wu, Frederick C, Wu, Jianfeng, Wu, Li Juan, Wu, Shouling, Xu, Haiquan, Xu, Liang, Yaacob, Nor Azwany, Yamborisut, Uruwan, Yan, Weili, Yang, Ling, Yang, Xiaoguang, Yang, Yang, Yardim, Nazan, Yaseri, Mehdi, Yasuharu, Tabara, Ye, Xingwang, Yiallouros, Panayiotis K, Yoosefi, Moein, Yoshihara, Akihiro, You, Qi Sheng, You, San-Lin, Younger-Coleman, Novie O, Md Yusof, Safiah, Yusoff, Ahmad Faudzi, Zaccagni, Luciana, Zafiropulos, Vassili, Zainuddin, Ahmad A, Zakavi, Seyed Rasoul, Zamani, Farhad, Zambon, Sabina, Zampelas, Antoni, Zamrazilová, Hana, Zapata, Maria Elisa, Zargar, Abdul Hamid, Ko Zaw, Ko, Zdrojewski, Tomasz, Zejglicova, Kristyna, Vrkic, Tajana Zeljkovic, Zeng, Yi, Zhang, Luxia, Zhang, Zhen-Yu, Zhao, Dong, Zhao, Ming-Hui, Zhao, Wenhua, Zhen, Shiqi, Zheng, Wei, Zheng, Yingfeng, Zholdin, Bekbolat, Zhou, Maigeng, Zhu, Dan, Zins, Marie, Zitt, Emanuel, Zocalo, Yanina, Cisneros, Julio Zuñiga, Zuziak, Monika, Ezzati, Majid, Filippi, Sarah, Cohortes épidémiologiques en population (CONSTANCES), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Université Paris Cité (UPCité), Université Paris Cité (UPCité), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, and Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)

Subjects
Population -- Health aspects, Leanness, Baixo peso/Underweight, none, Double burden, alipainoisuus, tulotaso, global health, systematic analysis, Sedentary behaviors, RC1200, Prospective associations, 0302 clinical medicine, underweight, nälänhätä, Biology (General), skin and connective tissue diseases, Children, ComputingMilieux_MISCELLANEOUS, Body mass index, Human Nutrition & Health, education.field_of_study, Humane Voeding & Gezondheid, ylipaino, General Medicine, kansainvälinen vertailu, 3. Good health, World health, Medicine, A100 Pre-clinical Medicine, Population distribution, medicine.medical_specialty, QH301-705.5, Science, Socio-culturale, Nursing, Social sciences, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Thinness, SDG 3 - Good Health and Well-being, BMI, epidemiology, obesity, None, Humans, Obesidade/Obesity, SDG 2 - Zero Hunger, education, VLAG, US adults, Omvårdnad, body mass index, malnutrition, obesity, underweight, nutritional and metabolic diseases, medicine.disease, terveellisyys, Obesity, Faculdade de Ciências Sociais, Body Mass Index, Prevalence, Risk Factors, General Biochemistry, WIAS, lihavuus, RA, Demography, N.A, double burden, Settore MED/09 - Medicina Interna, alueelliset erot, Nutrition and Disease, Animal Nutrition, [SDV]Life Sciences [q-bio], Medizin, 030204 cardiovascular system & hematology, 0601 Biochemistry and Cell Biology, Change distribution of body mass index, RA0421, Voeding en Ziekte, Epidemiology, Medicine and Health Sciences, Global health, Índice de massa corporal/Body Mass Index, 030212 general & internal medicine, Underweight, painoindeksi, 2. Zero hunger, General Neuroscience, aliravitsemus, elintarvikkeet, health, Public Health, Global Health, Social Medicine and Epidemiology, Diervoeding, 3142 Public health care science, environmental and occupational health, purl.org/pe-repo/ocde/ford#3.01.03 [https], Chinese adults, pooled analysis, medicine.symptom, Diet quality, B120 Physiology, Research Article, trends, purl.org/pe-repo/ocde/ford#1.06.03 [https], prevalence, Population, Mothers, Genetics and Molecular Biology, 3121 Internal medicine, medicine, Life Science, ddc:610, 3125 Otorhinolaryngology, ophthalmology, kehonkoostumus, Nutrition, Australian adults, General Immunology and Microbiology, purl.org/pe-repo/ocde/ford#3.01.04 [https], Ciências sociais, Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, Malnutrition, Epidemiology and Global Health, sense organs, Estilos de Vida e Impacto na Saúde
Abstract

From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions., Wellcome Trust, Medical Research Council, peer-reviewed

Published
2021
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40. Paleoenvironmental Evolution and Sea Level Change in Saronikos Gulf (Aegean Sea, Greece): Evidence from the Piraeus Coastal Plain and Elefsis Bay Sedimentary Records

Author

Elina Aidona, Elisavet Skampa, Varvara Antoniou, Aggelos Pallikarakis, Jean-Philippe Goiran, Sofia Cheilaris, George Syrides, Ioannis P. Panagiotopoulos, Dimitris Vandarakis, Theodora Tsourou, Maria Triantaphyllou, Margarita D. Dimiza, Kosmas Pavlopoulos, Olga Koukousioura, Katerina Kouli, Eric Fouache, National and Kapodistrian University of Athens (NKUA), Aristotle University of Thessaloniki, Hellenic Centre for Marine Research (HCMR), Agricultural University of Athens, ARCHEORIENT - Environnements et sociétés de l'Orient ancien (Archéorient), Université Lumière - Lyon 2 (UL2)-Centre National de la Recherche Scientifique (CNRS), MÉDIATIONS - Sciences des lieux, sciences des liens, Sorbonne Université (SU), and Abu Dhabi University (ADU)

Subjects
010506 paleontology, Marsh, 010504 meteorology & atmospheric sciences, Coastal plain, Fauna, [SDE.MCG]Environmental Sciences/Global Changes, Geography, Planning and Development, benthic foraminifera, Aquatic Science, non-pollen palynomorphs, 01 natural sciences, Biochemistry, Foraminifera, 14. Life underwater, [SDU.ENVI]Sciences of the Universe [physics]/Continental interfaces, environment, TD201-500, Holocene, 0105 earth and related environmental sciences, Water Science and Technology, molluscs, geography, geography.geographical_feature_category, Water supply for domestic and industrial purposes, biology, stratigraphy, Hydraulic engineering, biology.organism_classification, Oceanography, 13. Climate action, Benthic zone, pollen, ostracods, Sedimentary rock, TC1-978, Bay, Geology, magnetic susceptibility
Abstract

International audience; Thorough faunal (benthic foraminifera, ostracods, molluscs) and palynomorph analyses as well as magnetic susceptibility measurements performed on the Piraeus coastal plain sedimentary sequences have shed light on the paleoenvironmental evolution of the area since ca. 9000 cal BP. Benthic and palynomorph assemblages along with magnetic susceptibility suggest a typical lagoonal environment with significant freshwater inputs at the eastern part of the plain after 8700 cal BP. Between 7500 and 5400 cal BP, microfaunal assemblages, mollusc fauna and magnetic susceptibility suggest a shallow marine paleoenvironment, with Piraeus forming a tied island in the center of the bay. Since ca. 4800 cal BP a closed oligohaline lagoon is evidenced in the western part of the Piraeus plain further developed to a marsh after 2800 cal BP, while a coastal environment associated with the fluvio-deltaic system of Kifissos and Korydallos Rivers is continually developing to the west. Signs of cultivation and grazing activities in the area are evidenced since the Early Bronze Age, culminating during the Classical Period. A comparison with a well-dated marine record, recovered from the nearby shallow Elefsis Bay, provides a reasonable estimation of ~5 mm/yr for the absolute sea level rise rate in the inner Saronikos Gulf during the Mid-Holocene.

Published
2021
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41. Modelling Processes and Products in the Cereal Chain

Author

Serafim Bakalis, Maria N. Charalambides, Aberham Hailu Feyissa, Jose Benedito, Cristina Castañé, Nickolas G. Kavallieratos, Pasquale Trematerra, Alexandros Koulouris, Isabel Sousa, Milica Pojić, Jordi Riudavets, Anabela Raymundo, Fabrizio Sarghini, Christos G. Athanassiou, Alberto Tonda, Ferruh Erdogdu, Ilija Djekic, Aurelien Briffaz, Otilia Carvalho, Guy Della Valle, Carvalho, Otilia, Charalambides, Maria N, Djekić, Ilija, Athanassiou, Christo, Bakalis, Serafim, Benedito, Jose, Briffaz, Aurelien, Castañé, Cristina, Della Valle, Guy, de Sousa, Isabel Maria Nune, Erdogdu, Ferruh, Feyissa, Aberham Hailu, Kavallieratos, Nickolas G, Koulouris, Alexandro, Pojić, Milica, Raymundo, Anabela, Riudavets, Jordi, Sarghini, Fabrizio, Trematerra, Pasquale, Tonda, Alberto, Producció Vegetal, Protecció Vegetal Sostenible, Université de Lisbonne, Imperial College London, University of Belgrade [Belgrade], University of Thessaly [Volos] (UTH), University of Copenhagen = Københavns Universitet (UCPH), Universitat Politècnica de València (UPV), Démarche intégrée pour l'obtention d'aliments de qualité (UMR QualiSud), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Avignon Université (AU)-Université de La Réunion (UR)-Université de Montpellier (UM)-Institut Agro - Montpellier SupAgro, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Institut de Recerca i Tecnologia Agroalimentàries = Institute of Agrifood Research and Technology (IRTA), Unité de recherche sur les Biopolymères, Interactions Assemblages (BIA), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Ankara Üniversitesi, Danmarks Tekniske Universitet = Technical University of Denmark (DTU), Agricultural University of Athens, International Hellenic University, University of Novi Sad, University of Naples Federico II = Università degli studi di Napoli Federico II, Università degli Studi del Molise = University of Molise (UNIMOL), Mathématiques et Informatique Appliquées (MIA Paris-Saclay), AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), European Cooperation in Science and Technology (COST) : CA15118., University of Copenhagen = Københavns Universitet (KU), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Avignon Université (AU)-Université de La Réunion (UR)-Université de Montpellier (UM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institute of Agrifood Research and Technology (IRTA), Technical University of Denmark [Lyngby] (DTU), University of Naples Federico II, University of Molise [Campobasso] (UNIMOL), University of Molise, Mathématiques et Informatique Appliquées (MIA-Paris), and Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-AgroParisTech-Université Paris-Saclay

Subjects
0106 biological sciences, cereals, food transformation, modelling, transformation processes, Health (social science), cereal, TECNOLOGIA DE ALIMENTOS, Computer science, Supply chain, Plant Science, Review, lcsh:Chemical technology, 01 natural sciences, Health Professions (miscellaneous), Microbiology, Field (computer science), Domain (software engineering), 0404 agricultural biotechnology, 010608 biotechnology, [SDV.IDA]Life Sciences [q-bio]/Food engineering, lcsh:TP1-1185, 2. Zero hunger, Consumption (economics), Science & Technology, business.industry, 04 agricultural and veterinary sciences, [INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation, 040401 food science, Risk analysis (engineering), Agriculture, Greenhouse gas, Food Science & Technology, Food processing, business, Transformation processes, Life Sciences & Biomedicine, 0908 Food Sciences, Food Science
Abstract

[EN] In recent years, modelling techniques have become more frequently adopted in the field of food processing, especially for cereal-based products, which are among the most consumed foods in the world. Predictive models and simulations make it possible to explore new approaches and optimize proceedings, potentially helping companies reduce costs and limit carbon emissions. Nevertheless, as the different phases of the food processing chain are highly specialized, advances in modelling are often unknown outside of a single domain, and models rarely take into account more than one step. This paper introduces the first high-level overview of modelling techniques employed in different parts of the cereal supply chain, from farming to storage, from drying to milling, from processing to consumption. This review, issued from a networking project including researchers from over 30 different countries, aims at presenting the current state of the art in each domain, showing common trends and synergies, to finally suggest promising future venues for research., The authors would like to acknowledge networking and article processing charge support by COST Action CA15118 (Mathematical and Computer Science Methods for Food Science and Industry).

Published
2020
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42. Diversity of breeding practices is linked to the use of collective tools for the genetic management of the Corsican sheep breed

Author

Anne Lauvie, I. Hadjigeorgiou, Lola Perucho, Christina Ligda, Charles-Henri Moulin, Jean-Christophe Paoli, Laboratoire de Recherches sur le Développement de l'Elevage (LRDE), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hellenic Agricultural Organization Demeter (HAO Demeter), Systèmes d'élevage méditerranéens et tropicaux (UMR SELMET), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad), and Agricultural University of Athens

Subjects
2. Zero hunger, 040301 veterinary sciences, Agroforestry, media_common.quotation_subject, [SDV]Life Sciences [q-bio], 0402 animal and dairy science, 04 agricultural and veterinary sciences, Biology, SF1-1100, 040201 dairy & animal science, Breed, language.human_language, Animal culture, 0403 veterinary science, language, breeding scheme, Breeding practices, milk recording, Animal Science and Zoology, Sheep breed, Corsican, Diversity (politics), media_common, local breed
Abstract

International audience; For breeding schemes based on a diversity of production systems, there is a growing challenge in combining standardised tools for the collective genetic improvement of a breed and the selection of a flock able to respond to the specific constraints of the farm and the farmer’s objectives. In order to progress on this question, it is necessary to gain better knowledge of how farmers who use one or several of these tools select the future breeding animals of their flocks, and the conditions under which they use these collective tools. We took the example of dairy sheep farming in Corsica (France) and of two collective tools for the Corsican breed’s management: the use of milk recording data within and outside of the breeding scheme and the buying of rams from the breeding scheme’s cooperative. The tools’ use and perception were described by means of interviews with farmers (n = 40). Cross-analysis of farms’ descriptors and the use of collective tools was performed by statistical analysis using available databases on dairy sheep flocks in Corsica. A diversity of breeding practices was associated to the use of milk recording data and to the purchase of rams sold by the breeding scheme’s cooperative. Flock size, milking method and type of land use influenced these breeding practices and the adoption or mistrust of a collective genetic improvement tool. Dissemination of genetic progress through rams from the breeding scheme is possible, provided that a diversity of breeding practices and production environments is represented in the nucleus flocks.Highlights Participating in the breeding scheme of the Corsican breed did not hinder the use of various replacement and culling practices in dairy sheep farms Modalities of use of the milk recording tool are multiple and driven by work organisation, perception of the breeding scheme and the farm project Rams sold by the breeding scheme’s cooperative are present in several commercial farms with varying characteristics.

Published
2020
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43. The chemical composition of impact craters on Titan

Author

Christos Matsoukas, Athena Coustenis, Catherine D. Neish, Bernard Schmitt, Ioannis Baziotis, Michael Malaska, Kenneth J. Lawrence, Olivier Witasse, Rosaly M. C. Lopes, Anezina Solomonidou, Ashley Schoenfeld, Nico Altobelli, Pierre Drossart, Coustenis Athena, Alice Le Gall, Laboratoire d'études spatiales et d'instrumentation en astrophysique (LESIA (UMR_8109)), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Agence Spatiale Européenne (ESA), European Space Agency (ESA), University of Western Ontario (UWO), European Space Astronomy Centre (ESAC), Czech University of Life Sciences Prague (CZU), Department of Earth Sciences [London, ON], Jet Propulsion Laboratory (JPL), California Institute of Technology (CALTECH)-NASA, PLANETO - LATMOS, Laboratoire Atmosphères, Milieux, Observations Spatiales (LATMOS), Sorbonne Université (SU)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS), European Space Research and Technology Centre (ESTEC), Department of Earth, Planetary and Space Sciences [Los Angeles] (EPSS), University of California [Los Angeles] (UCLA), University of California-University of California, Royal Institute of Technology [Stockholm] (KTH ), and Agricultural University of Athens

Subjects
geography, geography.geographical_feature_category, Alluvial fan, [SDU.ASTR.EP]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Earth and Planetary Astrophysics [astro-ph.EP], 15. Life on land, symbols.namesake, Atmospheric radiative transfer codes, Impact crater, 13. Climate action, [SDU]Sciences of the Universe [physics], Middle latitudes, symbols, Radiative transfer, Ejecta blanket, Titan (rocket family), Chemical composition, Geomorphology, Geology
Abstract

We investigate nine Titan impact craters using Visual and Infrared Mapping Spectrometer (VIMS) data and a radiative transfer code (RT) [e.g. 1] in addition to emissivity data, in order to constrain the spectral behavior and composition of the craters. Past studies have looked at the chemical composition of impact craters either by using qualitative comparisons between craters [e.g. 2;3] or by combining all craters into a single unit [4], rather than separating them by geographic location or degradation state. Here, we use a radiative transfer model to first estimate the atmospheric contribution to the data, then extract the surface albedos of the impact crater subunits, and finally constrain their composition by using a library of candidate Titan materials. Following the general characterization of the impact craters, we study two impact crater subunits, the ‘crater floor’, which refers to the bottom of a crater, and the ‘ejecta blanket’, which is the material thrown out of the crater during an impact event. The results show that Titan’s mid-latitude plain craters: Afekan, Soi, and Forseti, in addition to Sinlap and Menrva are enriched in an OH-bearing constituent (likely water-ice) in an organic based mixture, while the equatorial dune craters: Selk, Ksa, Guabonito, and Santorini, appear to be purely composed of organic material (mainly unknown dune dark material). This follows the pattern seen in [4], where midlatitude alluvial fans, undifferentiated plains, and labyrinths were found to consist of a tholin-like and water-ice mixture, while the equatorial undifferentiated plains, hummocky terrains, dunes, and variable plains were found to consist of a dark material and tholin-like mixture in their very top layers. These observations also agree with the evolution scenario proposed by [3], wherein the impact cratering process produces a mixture of organic material and water ice, which is later “cleaned” through fluvial erosion in the midlatitude plains; a cleaning process that does not appear to operate in the equatorial dunes, which seem to be quickly covered by a thin layer of sand sediment. This scenario agrees with other works that suggest that atmospheric deposition is similar in the low-latitudes and midlatitudes on Titan, but with more rain falling onto the higher latitudes causing additional processing of materials in those regions [e.g. 5]. In either case, it appears that active processes are working to shape the surface of Titan, and it remains a dynamic world in the present day.[1] Hirtzig, M., et al. (2013). Icarus, 226, 470–486; [2] Neish, C.D., et al. (2015), Geophys. Res. Lett. 42, 3746–3754; [3] Werynski, A., et al. (2019), Icarus, 321, 508-521; [4] Solomonidou, A., et al. (2018), J. Geophys. Res, 123, 2, 489-507; [5] Neish, A.C., et al. (2016), Icarus, 270, 114–129.

Published
2020
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44. Odor characterization of white wines produced from indigenous greek grape varieties using the frequency of attribute citation method with trained assessors

Author

Yorgos Kotseridis, Georgios Papadopoulos, Evangelia Nanou, Sophie Tempere, Emorfili Mavridou, Fotios S. Milienos, Agricultural University of Athens, Panteion University [Athens], Unité de Recherche Oenologie [Villenave d'Ornon], and Université de Bordeaux (UB)-Institut des Sciences de la Vigne et du Vin (ISVV)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)

Subjects
Health (social science), Trained panel, 030309 nutrition & dietetics, [SDV]Life Sciences [q-bio], Sensory aroma, Plant Science, Biology, lcsh:Chemical technology, Health Professions (miscellaneous), Microbiology, Sensory analysis, Article, 03 medical and health sciences, 0404 agricultural biotechnology, Cluster analysis, lcsh:TP1-1185, Aroma profile, 0303 health sciences, Mushroom, Greek wines, CATA, 04 agricultural and veterinary sciences, 040401 food science, Correspondence analysis, Frequency of attribute citation, Horticulture, Odor, [SDE]Environmental Sciences, Food Science
Abstract

The aim of this study was to investigate the sensory aroma profiles of white wines of the indigenous Greek grape varieties Assyrtiko, Malagousia, Moschofilero, and Roditis. Twenty-three panelists evaluated 17 wines of the aforementioned varieties using the frequency of attribute citation method. Three indices were calculated to assess panel performance in terms of reproducibility. Correspondence analysis and cluster analysis were employed to investigate the sensory space of the wines. Samples of the Roditis variety were characterized mainly by Banana and Vanilla odors, Assyrtiko samples had Earthy, Mushroom, and Nutty odors, as well as Lemon and Honey for some of the samples. Malagousia wines were described as having Lemon, Grapefruit, and Citrus blossom character, and they shared some descriptors with Assyrtiko wines, such as Mushroom and Earthy, and some with Moschofilero samples, i.e., floral and citrus notes. All Moschofilero wines exhibited a floral odor profile: specifically, Rose, Jasmine, or more Citrus blossom-like. Moreover, some Moschofilero samples also revealed a Grapefruit, Lemon, and/or Earthy character, while others expressed Honey notes. In conclusion, despite common characteristics found within varieties, some samples of different varieties exhibited overlapping profiles, and in some cases, samples of the same variety were quite different from each other.

Published
2020
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45. Decision support system for sustainable and GHG optimized milk production in key European areas (MilKey)

Author

AMON, Barbara, DÍAZ DE OTÁLORA AGUIRRE, Xabier, DRAGONI, Federico, JANKE, D., HANSEN, Anya, WINIWARTER, Wilfried, SUCHOWSKA-KISIELEWICZ, M., RYCHLA, Anna, BARTZANAS, Thomas, ANESTIS, Vasileiros, DEMEYER, Peter, VAN OVERBEKE, P., KROLL, Dominika, BUCKLEY, Cathal, WILFART, Aurélie, MITTENZWEI, Klaus, JØRGENSEN, G., DOLLE, Jean-Baptiste, CASTELLAN, Elisabeth, BREEN, James, MAZURKIEWICZ, J, PULKA, J, DACH, J, Leibniz-Institut für Agrartechnik und Bioökonomie (ATB), University of Zielona Góra, Agricultural University of Athens, Flanders Research Institute for Agriculture, Fisheries and Food, Belgium, Teagasc - Environment, Soils and Land-Use Department, Ireland, Sol Agro et hydrosystème Spatialisation (SAS), AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Norwegian Institute of Bioeconomy Research (NIBIO), Institut de l'élevage (IDELE), University College Dublin [Dublin] (UCD), Poznan University of Life Sciences (Uniwersytet Przyrodniczy w Poznaniu) (PULS), and EraNet Joint call 2018

Subjects
[SDV.SA.SPA]Life Sciences [q-bio]/Agricultural sciences/Animal production studies, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2020

46. Challenges and innovations for improving the sustainability of European agroforestry systems of high nature and cultural value: stakeholder perspectives

Author

Tibor Hartel, Valérie Viaud, Fernando Pulido, Paul J. Burgess, Anastasia Pantera, Antonello Franca, Gerardo Moreno, Anna Varga, Stéphanie Aviron, Josep Crous-Duran, Gioavanna Seddaiu, Staffan Berg, Joana Amaral Paulo, Victor Rolo, Jaconette Mirck, Claudine Thenail, João H.N. Palma, Universidad de Extremadura - University of Extremadura (UEX), INDEHESA, Forestry School, Babes-Bolyai University [Cluj-Napoca] (UBB), Biodiversité agroécologie et aménagement du paysage (UMR BAGAP), Ecole supérieure d'Agricultures d'Angers (ESA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-INSTITUT AGRO Agrocampus Ouest, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), European Forest Institute (EFI), Universidade de Lisboa = University of Lisbon (ULISBOA), CNR-ISPAAM, Istituto per il Sistema Produzione Animale in Ambiente Mediterraneo, National Research Council of Italy | Consiglio Nazionale delle Ricerche (CNR), EntoNative GmbH (Tenetrio), MV Agroecology Research Centre, Agricultural University of Athens, Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), MTA Centre for Ecological Research [Tihany], Hungarian Academy of Sciences (MTA), Sol Agro et hydrosystème Spatialisation (SAS), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-INSTITUT AGRO Agrocampus Ouest, Cranfield University, Regional government of Extremadura: 'Talento' fellowship (TA18022), European Project: 613520,EC:FP7:KBBE,FP7-KBBE-2013-7-single-stage,AGFORWARD(2014), University of Extremadura, AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Ecole supérieure d'Agricultures d'Angers (ESA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Universidade de Lisboa (ULISBOA), Consiglio Nazionale delle Ricerche [Roma] (CNR), University of Sassari, and Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)

Subjects
Value (ethics), Health (social science), Mosaic-like agriculture, 010504 meteorology & atmospheric sciences, Sociology and Political Science, media_common.quotation_subject, Geography, Planning and Development, Participatory action research, 010501 environmental sciences, Management, Monitoring, Policy and Law, 01 natural sciences, 12. Responsible consumption, Regional-based solution, 11. Sustainability, Production (economics), 0105 earth and related environmental sciences, Nature and Landscape Conservation, media_common, 2. Zero hunger, Sustainable development, Global and Planetary Change, Ecology, Agroforestry, Stakeholder, Silvopastoral systems, 15. Life on land, Adaptive policy, Participative innovation, European survey, 13. Climate action, Sustainability, [SDE]Environmental Sciences, Business, Landscape ecology, Diversity (politics)
Abstract

International audience; Traditional forms of agroforestry are often recognized as exemplar systems that successfully integrate food production, biodiversity conservation and high cultural values. However many traditional agroforestry systems in Europe are in decline or are threatened and the perspectives of local stakeholders on the production, management, socio-economic, and environmental dimensions of such systems are not fully understood. To fill this gap, we present results of participatory research performed with ten stakeholder groups (SG) across Europe to search for solutions to improve the economic and ecological sustainability of High Nature and Cultural Value agroforestry systems (HNCV agroforestry). Stakeholders included both users and beneficiaries of the HNCV agroforestry. First, SGs held open discussions (227 participants) to identify major challenges for the long-term sustainability of HNCV agroforestry. Challenges were classified into production, management, socio-economic and the environment categories. Second, they responded to structured questionnaires (120 respondents) that explored the positive and negative perceptions of 45 possible attributes of HNCV agroforestry. Third, innovative solutions were identified by individual and group discussions to address the four categories of challenge. Challenges were mostly identified for the management and socio-economic categories, but several challenges concerning production and environment were also pinpointed. Besides, solutions matched poorly with the challenges identified, and, while challenges were at some extent common across countries, solutions to address them were more case-specific. The successful implementation of these solutions requires an in-depth understanding of the diversity of socio-cultural and natural contexts of the HNCV agroforestry systems and building bottom-up proposals and collective actions based on this understanding. The sustainability of HNCV agroforestry would be benefited by providing farmers and managers with a financial advantage from the high nature and cultural value of these systems.

Published
2020
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47. Production of Microalgal Slow-Release Fertilizer by Valorizing Liquid Agricultural Digestate: Growth Experiments with Tomatoes

Author

Abdellatif Barakat, Florian Monlau, Raquel Jimenez, Saida Tayibi, Giorgos Markou, Camille Chapsal, APESA [Pau], Department of Natural Resources Management and Agricultural Engineering, Agricultural University of Athens, Hellenic Agricultural Organization Demeter (HAO Demeter), Ingénierie des Agro-polymères et Technologies Émergentes (UMR IATE), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Université de Montpellier (UM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Mohammed VI Polytechnic University [Marocco] (UM6P), and Nouvelle Aquitaine region (FRANCE), grant number 19R04

Subjects
020209 energy, Photobioreactor, Biomass, 02 engineering and technology, 010501 environmental sciences, engineering.material, 7. Clean energy, 01 natural sciences, lcsh:Technology, Monoraphidium, lcsh:Chemistry, nutrients leaching, Biogas, 0202 electrical engineering, electronic engineering, information engineering, General Materials Science, slow released fertilizer, photo-bioreactor, Leaching (agriculture), Instrumentation, lcsh:QH301-705.5, 0105 earth and related environmental sciences, 2. Zero hunger, Fluid Flow and Transfer Processes, biology, lcsh:T, [SDE.IE]Environmental Sciences/Environmental Engineering, Process Chemistry and Technology, circular economy, General Engineering, growth plant tests, biology.organism_classification, Pulp and paper industry, nutrients recycling, lcsh:QC1-999, Computer Science Applications, Anaerobic digestion, lcsh:Biology (General), lcsh:QD1-999, lcsh:TA1-2040, Digestate, engineering, Environmental science, Fertilizer, lcsh:Engineering (General). Civil engineering (General), lcsh:Physics
Abstract

Anaerobic Digestion (AD) is a process that is well-known and fast-developing in Europe. AD generates large amounts of digestate, especially in livestock-intensive areas. Digestate has potential environmental issues due to nutrients (such as nitrogen) lixiviation or volatilization. Using liquid digestate as a nutrient source for microalgae growth is considered beneficial because digestate could be valorized and upgraded by the production of an added value product. In this work, microalgal biomass produced using liquid digestate from an agricultural biogas plant was investigated as a slow-release fertilizer in tomatoes. Monoraphidium sp. was first cultivated at different dilutions (1:20, 1:30, 1:50), in indoor laboratory-scale trials. The optimum dilution factor was determined to be 1:50, with a specific growth rate of 0.13 d&minus, 1 and a complete nitrogen removal capacity in 25 days of culture. Then, outdoor experiments were conducted in a 110 dm3 vertical, closed photobioreactors (PBRs) in batch and semi-continuous mode with 1:50 diluted liquid digestate. During the batch mode, the microalgae were able to remove almost all NH4+ and 65 (&plusmn, 13) % of PO43&minus, while the microalgal growth rate reached 0.25 d&minus, 1. After the batch mode, the cultures were switched to operate under semi-continuously conditions. The cell densities were maintained at 1.3 &times, 107 cells mL&minus, 1 and a biomass productivity around 38.3 mg TSS L&minus, 1 d&minus, 1 during three weeks was achieved, where after that it started to decline due to unfavorable weather conditions. Microalgae biomass was further tested as a fertilizer for tomatoes growth, enhancing by 32% plant growth in terms of dry biomass compared with the control trials (without fertilization). Similar performances were achieved in tomato growth using synthetic fertilizer or digestate. Finally, the leaching effect in soils columns without plant was tested and after 25 days, only 7% of N was leached when microalgae were used, against 50% in the case of synthetic fertilizer.

Published
2020
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48. Feeding of carob (Ceratonia siliqua) to sheep infected with gastrointestinal nematodes reduces faecal egg counts and worm fecundity

Author

Irene Mueller-Harvey, Nikolaos Voutzourakis, Katerina Saratsi, Smaragda Sotiraki, S. Ioannis Hadjigeorgiou, Nikolaos Tzanidakis, Hervé Hoste, Stig Milan Thamsborg, Alexandros Stefanakis, Hellenic Agricultural Organization Demeter (HAO Demeter), Agricultural University of Athens, Interactions hôtes-agents pathogènes [Toulouse] (IHAP), Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Department of Veterinary and Animal Sciences [Copenhagen], Faculty of Health and Medical Sciences, University of Copenhagen = Københavns Universitet (KU)-University of Copenhagen = Københavns Universitet (KU), School of Agriculture, Policy and Development, University of Reading (UOR), and This article is based upon work from EMIDA ERA-Net project CARES and COST Action COMBAR CA16230 (European Cooperation in Science and Technology).

Subjects
0301 basic medicine, Nematoda, Trichostrongylus, Gastrointestinal Diseases, Adult worm, [SDV]Life Sciences [q-bio], MESH: Parasite Egg Count, MESH: Trichostrongylosis, Galactans, MESH: Trichostrongylus, Mannans, Feces, 0302 clinical medicine, Carob, Haemonchus contortus, Plant Gums, Feed additives, MESH: Animals, Anthelmintic, 2. Zero hunger, Anthelmintics, biology, MESH: Sheep Diseases, MESH: Feces, Trichostrongylosis, General Medicine, 030108 mycology & parasitology, Fecundity, MESH: Anthelmintics, Proanthocyanidin, MESH: Haemonchus, Haemonchus, medicine.drug, Gastrointestinal nematodes, MESH: Haemonchiasis, 030231 tropical medicine, MESH: Sheep, Sheep Diseases, Trichostrongylus colubriformis, MESH: Nematoda, Sainfoin, 03 medical and health sciences, food, Animal science, MESH: Diet, MESH: Mannans, PEG ratio, parasitic diseases, medicine, Animals, Parasite Egg Count, MESH: Gastrointestinal Diseases, MESH: Plant Gums, Sheep, General Veterinary, MESH: Galactans, biology.organism_classification, food.food, Diet, Ceratonia siliqua, Parasitology, Haemonchiasis
Abstract

International audience; The present study explored the anthelmintic effects of condensed tannins (CT) in carob (Ceratonia siliqua) pods fed to sheep against gastrointestinal nematodes. Three independent in vivo trials tested whether i) carob pod (CaBP)-containing feed had an anthelmintic effect and if yes, which was the optimal concentration in the diet; ii) whether this effect could be attributed to tannins through the polyethylene glycol (PEG) test and iii) whether there were any synergistic effects when combined with another tannin-containing feed (e.g. sainfoin). In all trials 6-month old nematode-naive lambs, experimentally infected with both Haemonchus contortus and Trichostrongylus colubriformis, were used. Faecal egg counts (FEC) were performed regularly and at the end of each trial adult worm counts (AWC) and female worm fecundity were recorded. In trial 1, 35 lambs (five groups of seven lambs) were fed different CaBP concentrations ranging from 0% to 12 % w/w. FEC declined up to 39.2 % only in the group fed with 12 %CaBP, while a declining trend (P

Published
2020
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49. Identification and Detection of a Novel Point Mutation in the Chitin Synthase Gene of Culex Pipiens Associated With Diflubenzuron Resistance

Author

Emmanouil A. Fotakis, Alexandra Chaskopoulou, Daniele Porretta, Mylène Weill, Hugo Osório, Arianna Puggioli, Linda Grigoraki, Romeo Bellini, John Vontas, Sandra Urbanelli, Valentina Mastrantonio, Agricultural University of Athens, Institute of Molecular Biology and Biotechnology (IMBB-FORTH), Foundation for Research and Technology - Hellas (FORTH), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Liverpool School of Tropical Medicine (LSTM), Centro Agricoltura Ambiente 'Giorgio Nicoli' (CAA), European Biological Control Laboratory (EBCL), United States Department of Agriculture (USDA), Instituto Nacional de Saùde Dr Ricardo Jorge [Portugal] (INSA), Institut des Sciences de l'Evolution de Montpellier (UMR ISEM), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre National de la Recherche Scientifique (CNRS)-Institut de recherche pour le développement [IRD] : UR226, Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-École Pratique des Hautes Études (EPHE), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Institut de recherche pour le développement [IRD] : UR226-Centre National de la Recherche Scientifique (CNRS)

Subjects
0106 biological sciences, Insecticides, Polymers, viruses, Chitin Synthase Gene, RC955-962, Gene Identification and Analysis, Chitin, Disease Vectors, medicine.disease_cause, Mosquitoes, 01 natural sciences, Geographical locations, Insecticide Resistance, chemistry.chemical_compound, Arctic medicine. Tropical medicine, Medicine and Health Sciences, Missense mutation, Materials, Genetics, 0303 health sciences, Mutation, biology, Mediterranean Region, Eukaryota, Agriculture, 3. Good health, Insects, Europe, Chemistry, Culex, Mosquito control, Infectious Diseases, Diflubenzuron, Italy, Macromolecules, Physical Sciences, Insect Proteins, Public aspects of medicine, RA1-1270, Agrochemicals, Culex Pipiens, Research Article, Substitution Mutation, Arthropoda, Materials Science, Mutation, Missense, insecticide resistance, mosquito, vector control, 03 medical and health sciences, Culex pipiens, qx_600, medicine, Animals, Point Mutation, European Union, Identification and Detection, Mutation Detection, Larvicide, Allele frequency, 030304 developmental biology, Infecções Sistémicas e Zoonoses, Chitin Synthase, Point mutation, fungi, Organisms, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Polymer Chemistry, biology.organism_classification, Invertebrates, Insect Vectors, Species Interactions, [SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics, 010602 entomology, qx_530, chemistry, qu_550, People and places
Abstract

Background Diflubenzuron (DFB) is one of the most used insecticides in mosquito larval control including that of Culex pipiens, the proven vector of the recent West Nile Virus epidemics in Europe. Two mutations (I1043L and I1043M) in the chitin synthase (CHS) putative binding site of DFB have been previously reported in Cx. pipiens from Italy and associated with high levels of resistance against this larvicide. Methodology/Principal findings Here we report the identification of a third mutation at the same I1043 position of the CHS gene resulting in the substitution of Isoleucine to Phenylalanine (I1043F). This mutation has also been found in agricultural pests and has been functionally validated with genome editing in Drosophila, showing to confer striking levels (>15,000 fold) of DFB resistance. The frequency of the I1043F mutation was found to be substantially higher in Cx. pipiens mosquitoes surviving DFB doses largely exceeding the recommended field dose, raising concerns about the future efficient use of this insecticide. We monitored the presence and frequency of DFB mutations in Cx. pipiens mosquitoes from several Mediterranean countries, including Italy, France, Greece, Portugal and Israel. Among the Cx. pipiens populations collected in Northern Italy all but one had at least one of the three DFB mutations at allele frequencies reaching 93.3% for the I1043M, 64.8% for the I1043L and 10% for the I1043F. The newly reported I1043F mutation was also identified in two heterozygote individuals from France (4.2% allelic frequency). In contrast to Italy and France, no DFB resistant mutations were identified in the Cx. pipiens mosquitoes sampled from Greece, Portugal and Israel. Conclusions/Significance The findings of our study are of major concern for mosquito control programs in Europe, that rely on the use of a limited number of available larvicides, and highlight the necessity for the development of appropriate Insecticide Resistance Management (IRM) programs, to ensure the sustainable use of DFB., Author summary Diflubenzuron is one of the main larvicides used for the control of the West Nile Virus vector Culex pipiens in the Mediterranean. However, the efficiency of control is now under threat due to the selection of insecticide resistance. Two point mutations were previously identified at the Chitin synthase and shown to confer low and high levels of resistance and a diagnostic was developed to monitor the trait. This study reports the identification of a third mutation associated with high levels of diflubenzuron resistance in Italy. This mutation was also detected in France, whereas no resistance mutations were found in Cx. pipiens mosquitoes sampled from Greece, Portugal and Israel. The findings are of major concern for mosquito control programs in S. Europe, which rely on the use of a limited number of larvicides.

Published
2020
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50. The chemical composition of impact craters on Titan

Author

Ioannis Baziotis, Rosaly M. C. Lopes, Michael Malaska, Pierre Drossart, Kenneth J. Lawrence, Ashley Schoenfeld, Christos Matsoukas, Anezina Solomonidou, Alyssa Werynski, Athena Coustenis, Olivier Witasse, Nicolas Altobelli, Catherine D. Neish, Alice Le Gall, European Space Astronomy Centre (ESAC), European Space Agency (ESA), Department of Earth Sciences [London, ON], University of Western Ontario (UWO), Laboratoire d'études spatiales et d'instrumentation en astrophysique (LESIA (UMR_8109)), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Jet Propulsion Laboratory (JPL), California Institute of Technology (CALTECH)-NASA, PLANETO - LATMOS, Laboratoire Atmosphères, Milieux, Observations Spatiales (LATMOS), Sorbonne Université (SU)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS), European Space Research and Technology Centre (ESTEC), Department of Earth, Planetary and Space Sciences [Los Angeles] (EPSS), University of California [Los Angeles] (UCLA), University of California-University of California, Royal Institute of Technology [Stockholm] (KTH ), Agricultural University of Athens, NASA-California Institute of Technology (CALTECH), and Institut de l'élevage (IDELE)

Subjects
geography, geography.geographical_feature_category, Alluvial fan, [SDU.ASTR.EP]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Earth and Planetary Astrophysics [astro-ph.EP], Mineralogy, Fluvial, symbols.namesake, Atmospheric radiative transfer codes, Impact crater, 13. Climate action, [SDU]Sciences of the Universe [physics], symbols, Radiative transfer, Ejecta blanket, Titan (rocket family), Chemical composition, Geology, ComputingMilieux_MISCELLANEOUS
Abstract

International audience; We investigate nine Titan impact craters using Visual and Infrared Mapping Spectrometer (VIMS) data and a radiative transfer code (RT) [e.g. 1] in addition to emissivity data, in order to constrain the spectral behavior and composition of the craters. Past studies have looked at the chemical composition of impact craters either by using qualitative comparisons between craters [e.g. 2;3] or by combining all craters into a single unit [4], rather than separating them by geographic location or degradation state. Here, we use a radiative transfer model to first estimate the atmospheric contribution to the data, then extract the surface albedos of the impact crater subunits, and finally constrain their composition by using a library of candidate Titan materials. Following the general characterization of the impact craters, we study two impact crater subunits, the 'crater floor', which refers to the bottom of a crater, and the 'ejecta blanket', which is the material thrown out of the crater during an impact event. The results show that Titan's mid-latitude plain craters: Afekan, Soi, and Forseti, in addition to Sinlap and Menrva are enriched in an OH-bearing constituent (likely water-ice) in an organic based mixture, while the equatorial dune craters: Selk, Ksa, Guabonito, and Santorini, appear to be purely composed of organic material (mainly unknown dune dark material). This follows the pattern seen in [4], where midlatitude alluvial fans, undifferentiated plains, and labyrinths were found to consist of a tholin-like and water-ice mixture, while the equatorial undifferentiated plains, hummocky terrains, dunes, and variable plains were found to consist of a dark material and tholin-like mixture in their very top layers. These observations also agree with the evolution scenario proposed by [3], wherein the impact cratering process produces a mixture of organic material and water ice, which is later "cleaned" through fluvial erosion in the midlatitude plains; a cleaning process that does not appear to operate in the equatorial dunes, which seem to be quickly covered by a thin layer of sand sediment. This scenario agrees with other works that suggest that atmospheric deposition is similar in the low-latitudes and midlatitudes on Titan, but with more rain falling onto the higher latitudes causing additional processing of materials in those regions [e.g. 5]. In either case, it appears that active processes are working to shape the surface of Titan, and it remains a dynamic world in the present day.[1] Hirtzig, M., et al. (2013). Icarus, 226, 470-486; [2] Neish, C.D., et al. (2015), Geophys. Res. Lett. 42, 3746-3754; [3] Werynski, A., et al. (2019), Icarus, 321, 508-521; [4] Solomonidou, A., et al. (2018), J. Geophys. Res, 123, 2, 489-507; [5] Neish, A.C., et al. (2016), Icarus, 270, 114-129.&

Published
2020
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