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1. Symptomatic vs. non-symptomatic device-related thrombus after LAAC: a sub-analysis from the multicenter EUROC-DRT registry

Author

Vij, Vivian, Cruz-González, Ignacio, Galea, Roberto, Piayda, Kerstin, Nelles, Dominik, Vogt, Lara, Gloekler, Steffen, Fürholz, Monika, Meier, Bernhard, Räber, Lorenz, O’Hara, Gilles, Arzamendi, Dabit, Agudelo, Victor, Asmarats, Lluis, Freixa, Xavier, Flores-Umanzor, Eduardo, De Backer, Ole, Sondergaard, Lars, Nombela-Franco, Luis, McInerney, Angela, Salinas, Pablo, Korsholm, Kasper, Nielsen-Kudsk, Jens Erik, Afzal, Shazia, Zeus, Tobias, Operhalski, Felix, Schmidt, Boris, Montalescot, Gilles, Guedeney, Paul, Iriart, Xavier, Miton, Noelie, Saw, Jacqueline, Gilhofer, Thomas, Fauchier, Laurent, Veliqi, Egzon, Meincke, Felix, Petri, Nils, Nordbeck, Peter, Gonzalez-Ferreiro, Rocio, Bhatt, Deepak L., Laricchia, Alessandra, Mangieri, Antonio, Omran, Heyder, Schrickel, Jan Wilko, Rodes-Cabau, Josep, Nickenig, Georg, Sievert, Horst, and Sedaghat, Alexander

Published
2023
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3. Registro español de hemodinámica y cardiología intervencionista. XXXIII informe oficial de la Asociación de Cardiología Intervencionista de la Sociedad Española de Cardiología (1990–2023)

Author

Carballo Garrido, Julio, Andraka, Leire, Gómez Jaume, Alfredo, Merino Otermin, Álvaro, Artáiz Urdaci, Miguel, Ruiz Salmerón, Rafael, Pérez de Prado, Armando, Cruz González, Ignacio, Calviño Santos, Ramon, Bayón, Jeremías, Trillo, Ramiro, Antonio Baz, José, Berenguer, Alberto, Casanova Sandoval, Juan M., Álvarez Antón, Salvador, Sabaté, Manel, Ruiz Nodar, Juan Miguel, Valero Picher, Ernesto, Amat Santos, Ignacio J., Ruiz Arroyo, José Ramón, Pinar Bermúdez, Eduardo, Íñigo-García, Luis Antonio, Arzamendi, Dabit, Jerez Valero, Miguel, Cerrato García, Pablo, Bosch Peligero, Eduard, Vaquerizo Montilla, Beatriz, Subinas Elorriaga, Asier, Sánchez Pérez, Ignacio, Jiménez Mazuecos, Francisco Javier, Tejada Ponce, David, Santos Martínez, Sandra, Moreu, José, Elízaga, Jaime, Cascón Pérez, José Domingo, García, Eulogio, Mainar, Vicente, Ávila González, María del Mar, Vergara, Rubén, Macaya, Carlos, Rasines Rodríguez, Alejandro, Fernández-Ortiz, Antonio, Ojeda Pineda, Soledad, Bethencourt González, Armando, Palazuelos, Jorge, López Palop, Ramón, Alegría Barrero, Eduardo, Camacho Freire, Santiago Jesús, Portero Pérez, María Pilar, Peña Perez, Gonzalo, Vázquez Álvarez, María Eugenia, Roura, Gerard, Agudelo, Víctor, Freixa, Xavier, Carrillo, Xavier, Mohandes, Mohsen, Muñoz Camacho, Juan F., Millán, Raúl, García del Blanco, Bruno, Sarnago, Fernando, Torres Bosco, Alfonso, Sáez, Roberto, Avanzas, Pablo, Pérez Vizcayno, María José, Caballero Borrego, Juan, Blanco Mata, Roberto, Merchán Herrera, Antonio, Luengo Mondéjar, Pablo, Lozano, Íñigo, Portales Fernández, Javier, Bosa Ojeda, Francisco, Martín Lorenzo, Pedro, Novo García, Enrique, Fernández Guerrero, Juan Carlos, González Caballero, Eva, Rivero, Fernando, Pomar, Francisco, Ruiz Quevedo, Valeriano, Morales Ponce, Francisco José, Ruiz García, Juan, Romero Vazquiánez, Manuela, Tellería, Miren, Baello Monge, Pascual, Botas Rodríguez, Javier, Franco Peláez, Juan Antonio, Unzue, Leire, Gómez Menchero, Antonio Enrique, Sánchez Recalde, Ángel, Jurado Román, Alfonso, Sainz Laso, Fermín, Fuertes Ferre, Georgina, Pimienta González, Raquel, Oteo Domínguez, Juan Francisco, Gutiérrez, Alejandro, Bullones Ramírez, Juan Antonio, Sánchez-Aquino González, Rosa, Frutos Garcia, Araceli, Fajardo Molina, Ricardo, Núñez Pernas, Daniel, Alonso Briales, Juan Horacio, Sánchez Gila, Joaquín, Sánchez Burguillos, Francisco J., Guisado Rasco, Agustín, Vizcaino Arellano, Manuela, Díez Gil, José Luis, de la Borbolla Fernández, Rafael García, Ramírez, Antonio, Larman, Mariano, Bastante, Teresa, Martín-Moreiras, Javier, and Cid Álvarez, Ana Belén

Published
2024
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4. Spanish cardiac catheterization and coronary intervention registry. 32nd official report of the Interventional Cardiology Association of the Spanish Society of Cardiology (1990-2022)

Author

Sarnago Cebada, Fernando, Baz, José Antonio, Lozano, Íñigo, Sabaté, Manel, Jiménez, Jesús, Íñigo García, Luis Antonio, Subinas Elorriaga, Asier, Berenguer Jofresa, Alberto, Novo García, Enrique, Pérez Vizcayno, María José, Carrillo Suárez, Xavier, Pinar Bermúdez, Eduardo, Calviño Santos, Ramón, Álvarez Antón, Salvador, Trillo Nouche, Ramiro, Ruíz Arroyo, José Ramón, Fernández Cisnal, Agustín, Amat-Santos, Ignacio J., Jerez Valero, Miguel, Rama Merchán, Juan Carlos, Vaquerizo, Beatriz, Tejada Ponce, David, Ruiz Nodar, Juan Miguel, Sánchez Pérez, Ignacio, Tejedor, Paula, Elizaga, Jaime, Jiménez Cabrera, Francisco Manuel, Bullones Ramírez, Juan Antonio, Sánchez Aquino, Rosa, Portero Pérez, María Pilar, Roura, Gerard, Mohandes, Mohsen, Sáez Moreno, Roberto, Avanzas, Pablo, Caballero, Juan, Torres Bosco, Alfonso Miguel, Merchán Herrera, Antonio, Robles Alonso, Javier, Bosa Ojeda, Francisco, García San Román, Koldobika, Agudelo, Victor Hugo, Martin Lorenzo, Pedro, Fernández, Juan Carlos, Pérez de Prado, Armando, Ruiz Quevedo, Valeriano, Cruz González, Ignacio, Moreu Burgos, José, Ruiz García, Juan, Sánchez Burguillos, Francisco José, Núñez Pernas, Daniel, Baello Monge, Pascual, Hernando Marrupe, Lorenzo, Franco Peláez, Juan Antonio, Jurado Román, Alfonso, Pomar Domingo, Francisco, Fuertes Ferre, Georgina, Pimienta González, Raquel, Morales Ponce, Francisco José, Sánchez Recalde, Ángel, Ojeda Pineda, Soledad, Frutos Garcia, Araceli, Millán Segovia, Raúl, Fajardo Molina, Ricardo, Díez Gil, José Luis, Guisado Rasco, Agustín, Gómez Menchero, Antonio Enrique, Bosch, Eduard, Oteo Domínguez, Juan Francisco, Gutiérrez-Barrios, Alejandro, Cascón Pérez, José Domingo, Casanova Sandoval, Juan Manuel, Fernández Portales, Javier, Rivero Crespo, Fernando, Gonzalez Caballero, Eva, Ocaranza Sánchez, Raymundo, Zueco, Javier, García del Blanco, Bruno, Alonso Briales, Juan Horacio, Sánchez Gila, Joaquín, Vizcaino Arellano, Manuel, Carballo Garrido, Julio, Andraka, Leire, Gómez Jaume, Alfredo, Merino Otermin, Álvaro, Artaiz Urdaci, Miguel, Arellano Serrano, Carlos, García, Eulogio, Unzué, Leire, Arzamendi, Dabit, Freixa, Xavier, Mainar, Vicente, Usón, Mariano, Palazuelos Molinero, Jorge, López Palop, Ramón, Bethencourt, Armando, Alegría Barrero, Eduardo, Camacho Freire, Santiago Jesús, Peña, Gonzalo, Vázquez Álvarez, María Eugenia, Muñoz Camacho, Juan Francisco, Ramírez Moreno, Antonio, Larman Tellechea, Mariano, García de la Borbolla Fernández, Rafael, Jurado-Román, Alfonso, Cid, Belén, and Cruz-González, Ignacio

Published
2023
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5. Registro español de hemodinámica y cardiología intervencionista. XXXII informe oficial de la Asociación de Cardiología Intervencionista de la Sociedad Española de Cardiología (1990-2022)

Author

Sarnago Cebada, Fernando, Baz, José Antonio, Lozano, Íñigo, Sabaté, Manel, Jiménez, Jesús, Íñigo García, Luis Antonio, Subinas Elorriaga, Asier, Berenguer Jofresa, Alberto, Novo García, Enrique, Pérez Vizcayno, María José, Carrillo Suárez, Xavier, Pinar Bermúdez, Eduardo, Calviño Santos, Ramón, Álvarez Antón, Salvador, Trillo Nouche, Ramiro, Ruíz Arroyo, José Ramón, Fernández Cisnal, Agustín, Amat-Santos, Ignacio J., Jerez Valero, Miguel, Rama Merchán, Juan Carlos, Vaquerizo, Beatriz, Tejada Ponce, David, Ruiz Nodar, Juan Miguel, Sánchez Pérez, Ignacio, Tejedor, Paula, Elizaga, Jaime, Jiménez Cabrera, Francisco Manuel, Bullones Ramírez, Juan Antonio, Sánchez Aquino, Rosa, Portero Pérez, María Pilar, Roura, Gerard, Mohandes, Mohsen, Sáez Moreno, Roberto, Avanzas, Pablo, Caballero, Juan, Torres Bosco, Alfonso Miguel, Merchán Herrera, Antonio, Robles Alonso, Javier, Bosa Ojeda, Francisco, García San Román, Koldobika, Agudelo, Victor Hugo, Martin Lorenzo, Pedro, Fernández, Juan Carlos, Pérez de Prado, Armando, Ruiz Quevedo, Valeriano, Cruz González, Ignacio, Moreu Burgos, José, Ruiz García, Juan, Sánchez Burguillos, Francisco José, Núñez Pernas, Daniel, Baello Monge, Pascual, Hernando Marrupe, Lorenzo, Franco Peláez, Juan Antonio, Jurado Román, Alfonso, Pomar Domingo, Francisco, Fuertes Ferre, Georgina, Pimienta González, Raquel, Morales Ponce, Francisco José, Sánchez Recalde, Ángel, Ojeda Pineda, Soledad, Frutos Garcia, Araceli, Millán Segovia, Raúl, Fajardo Molina, Ricardo, Díez Gil, José Luis, Guisado Rasco, Agustín, Gómez Menchero, Antonio Enrique, Bosch, Eduard, Oteo Domínguez, Juan Francisco, Gutiérrez-Barrios, Alejandro, Cascón Pérez, José Domingo, Casanova Sandoval, Juan Manuel, Fernández Portales, Javier, Rivero Crespo, Fernando, Gonzalez Caballero, Eva, Ocaranza Sánchez, Raymundo, Zueco, Javier, García del Blanco, Bruno, Alonso Briales, Juan Horacio, Sánchez Gila, Joaquín, Vizcaino Arellano, Manuel, Carballo Garrido, Julio, Andraka, Leire, Gómez Jaume, Alfredo, Merino Otermin, Álvaro, Artaiz Urdaci, Miguel, Arellano Serrano, Carlos, García, Eulogio, Unzué, Leire, Arzamendi, Dabit, Freixa, Xavier, Mainar, Vicente, Usón, Mariano, Palazuelos Molinero, Jorge, López Palop, Ramón, Bethencourt, Armando, Alegría Barrero, Eduardo, Camacho Freire, Santiago Jesús, Peña, Gonzalo, Vázquez Álvarez, María Eugenia, Muñoz Camacho, Juan Francisco, Ramírez Moreno, Antonio, Larman Tellechea, Mariano, García de la Borbolla Fernández, Rafael, Jurado-Román, Alfonso, Cid, Belén, and Cruz-González, Ignacio

Published
2023
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6. Clinical and echocardiographic risk factors for device-related thrombus after left atrial appendage closure: an analysis from the multicenter EUROC-DRT registry

Author

Vij, Vivian, Piayda, Kerstin, Nelles, Dominik, Gloekler, Steffen, Galea, Roberto, Fürholz, Monika, Meier, Bernhard, Valgimigli, Marco, O’Hara, Gilles, Arzamendi, Dabit, Agudelo, Victor, Asmarats, Lluis, Freixa, Xavier, Flores-Umanzor, Eduardo, De Backer, Ole, Sondergaard, Lars, Nombela-Franco, Luis, McInerney, Angela, Korsholm, Kasper, Nielsen-Kudsk, Jens Erik, Afzal, Shazia, Zeus, Tobias, Operhalski, Felix, Schmidt, Boris, Montalescot, Gilles, Guedeney, Paul, Iriart, Xavier, Miton, Noelie, Saw, Jacqueline, Gilhofer, Thomas, Fauchier, Laurent, Veliqi, Egzon, Meincke, Felix, Petri, Nils, Nordbeck, Peter, Ognerubov, Dmitrii, Merkulov, Evgeny, Cruz-González, Ignacio, Gonzalez-Ferreiro, Rocio, Bhatt, Deepak L., Laricchia, Alessandra, Mangieri, Antonio, Omran, Heyder, Schrickel, Jan Wilko, Rodes-Cabau, Josep, Sievert, Horst, Nickenig, Georg, and Sedaghat, Alexander

Published
2022
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7. Impact of gender in patients with device-related thrombosis after left atrial appendage closure -- a sub-analysis from the multicenter EUROC-DRT-registry

Author

Saw, Jacqueline, primary, Vij, Vivian, additional, Galea, Roberto, additional, Piayda, Kerstin, additional, Nelles, Dominik, additional, Vogt, Lara, additional, Gloekler, Steffen, additional, Fürholz, Monika, additional, Meier, Bernhard, additional, Räber, Lorenz, additional, O'Hara, Gilles, additional, Arzamendi, Dabit, additional, Agudelo, Victor, additional, Asmarats, Lluis, additional, Freixa, Xavier, additional, Flores-Umanzor, Eduardo J, additional, Backer, Ole De, additional, Sondergaard, Lars, additional, Franco, Luis Nombela, additional, Salinas, Pablo, additional, Korsholm, Kasper, additional, Nielsen-Kudsk, Jens Erik, additional, Zeus, Tobias, additional, Operhalski, Felix, additional, Schmidt, Boris, additional, Montalescot, Gilles, additional, Guedeney, Paul, additional, Iriart, Xavier, additional, Miton, Noelie, additional, Gilhofer, Thomas, additional, Fauchier, Laurent, additional, Veliqi, Egzon, additional, Meincke, Felix, additional, Petri, Nils, additional, Nordbeck, Peter, additional, Gonzalez-Ferreiro, Rocio, additional, Cruz-González, Ignacio, additional, L, Deepak Bhatt, additional, Laricchia, Alessandra, additional, Mangieri, Antonio, additional, Omran, Heyder, additional, Schrickel, Jan Wilko, additional, Beiert, Thomas, additional, Rodes-Cabau, Josep, additional, Nickenig, Georg, additional, Sievert, Horst, additional, Sedaghat, Alexander, additional, and Afzal, Shazia, additional

Published
2024
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8. Impact of gender in patients with device‐related thrombosis after left atrial appendage closure – A sub‐analysis from the multicenter EUROC‐DRT‐registry.

Author

Saw, Jacqueline, Vij, Vivian, Galea, Roberto, Piayda, Kerstin, Nelles, Dominik, Vogt, Lara, Gloekler, Steffen, Fürholz, Monika, Meier, Bernhard, Räber, Lorenz, O'Hara, Gilles, Arzamendi, Dabit, Agudelo, Victor, Asmarats, Lluis, Freixa, Xavier, Flores‐Umanzor, Eduardo, De Backer, Ole, Sondergaard, Lars, Nombela‐Franco, Luis, and Salinas, Pablo

Subjects
THROMBOSIS risk factors, RISK assessment, PROSTHETICS, ANTICOAGULANTS, SEX distribution, ARTIFICIAL implants, DESCRIPTIVE statistics, REPORTING of diseases, VITAMIN K, SURGICAL complications, KAPLAN-Meier estimator, ATRIAL fibrillation, LEFT atrial appendage closure, ADVERSE health care events, CONFIDENCE intervals, STROKE, COMORBIDITY, CHEMICAL inhibitors
Abstract

Background: Device‐related thrombosis (DRT) is a common finding after left atrial appendage closure (LAAC) and is associated with worse outcomes. As women are underrepresented in clinical studies, further understanding of sex differences in DRT patients is warranted. Methods and Results: This sub‐analysis from the EUROC‐DRT‐registry compromises 176 patients with diagnosis of DRT after LAAC. Women, who accounted for 34.7% (61/176) of patients, were older (78.0 ± 6.7 vs. 74.9 ± 9.1 years, p =.06) with lower rates of comorbidities. While DRT was detected significantly later in women (173 ± 267 vs. 127 ± 192 days, p =.01), anticoagulation therapy was escalated similarly, mainly with initiation of novel oral anticoagulant (NOAC), vitamin K antagonist (VKA) or heparin. DRT resolution was achieved in 67.5% (27/40) of women and in 75.0% (54/72) of men (p =.40). In the remaining cases, an intensification/switch of anticoagulation was conducted in 50.% (9/18) of men and in 41.7% (5/12) of women. Final resolution was achieved in 72.5% (29/40) cases in women, and in 81.9% (59/72) cases in men (p =.24). Women were followed‐up for a similar time as men (779 ± 520 vs. 908 ± 687 days, p =.51). Kaplan–Meier analysis revealed no difference in mortality rates in women (Hazard Ratio [HR]: 1.73, 95%‐Confidence interval [95%‐CI]:.68–4.37, p =.25) and no differences in stroke (HR:.83, 95%‐CI:.30–2.32, p =.72) within 2 years after LAAC. Conclusion: Evaluation of risk factors and outcome revealed no differences between men and women, with DRT in women being diagnosed significantly later. Women should be monitored closely to assess for DRT formation/resolution. Treatment strategies appear to be equally effective. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Spanish cardiac catheterization and coronary intervention registry. 32nd official report of the Interventional Cardiology Association of the Spanish Society of Cardiology (1990-2022)

Author

Jurado-Román, Alfonso, primary, Freixa, Xavier, additional, Cid, Belén, additional, Cruz-González, Ignacio, additional, Sarnago Cebada, Fernando, additional, Baz, José Antonio, additional, Lozano, Íñigo, additional, Sabaté, Manel, additional, Jiménez, Jesús, additional, Íñigo García, Luis Antonio, additional, Subinas Elorriaga, Asier, additional, Berenguer Jofresa, Alberto, additional, Novo García, Enrique, additional, Pérez Vizcayno, María José, additional, Carrillo Suárez, Xavier, additional, Pinar Bermúdez, Eduardo, additional, Calviño Santos, Ramón, additional, Álvarez Antón, Salvador, additional, Trillo Nouche, Ramiro, additional, Ruíz Arroyo, José Ramón, additional, Fernández Cisnal, Agustín, additional, Amat-Santos, Ignacio J., additional, Jerez Valero, Miguel, additional, Rama Merchán, Juan Carlos, additional, Vaquerizo, Beatriz, additional, Tejada Ponce, David, additional, Ruiz Nodar, Juan Miguel, additional, Sánchez Pérez, Ignacio, additional, Tejedor, Paula, additional, Elizaga, Jaime, additional, Jiménez Cabrera, Francisco Manuel, additional, Bullones Ramírez, Juan Antonio, additional, Sánchez Aquino, Rosa, additional, Portero Pérez, María Pilar, additional, Roura, Gerard, additional, Mohandes, Mohsen, additional, Sáez Moreno, Roberto, additional, Avanzas, Pablo, additional, Caballero, Juan, additional, Torres Bosco, Alfonso Miguel, additional, Merchán Herrera, Antonio, additional, Robles Alonso, Javier, additional, Bosa Ojeda, Francisco, additional, García San Román, Koldobika, additional, Agudelo, Victor Hugo, additional, Martin Lorenzo, Pedro, additional, Fernández, Juan Carlos, additional, Pérez de Prado, Armando, additional, Ruiz Quevedo, Valeriano, additional, Cruz González, Ignacio, additional, Moreu Burgos, José, additional, Ruiz García, Juan, additional, Sánchez Burguillos, Francisco José, additional, Núñez Pernas, Daniel, additional, Baello Monge, Pascual, additional, Hernando Marrupe, Lorenzo, additional, Franco Peláez, Juan Antonio, additional, Jurado Román, Alfonso, additional, Pomar Domingo, Francisco, additional, Fuertes Ferre, Georgina, additional, Pimienta González, Raquel, additional, Morales Ponce, Francisco José, additional, Sánchez Recalde, Ángel, additional, Ojeda Pineda, Soledad, additional, Frutos Garcia, Araceli, additional, Millán Segovia, Raúl, additional, Fajardo Molina, Ricardo, additional, Díez Gil, José Luis, additional, Guisado Rasco, Agustín, additional, Gómez Menchero, Antonio Enrique, additional, Bosch, Eduard, additional, Oteo Domínguez, Juan Francisco, additional, Gutiérrez-Barrios, Alejandro, additional, Cascón Pérez, José Domingo, additional, Casanova Sandoval, Juan Manuel, additional, Fernández Portales, Javier, additional, Rivero Crespo, Fernando, additional, Gonzalez Caballero, Eva, additional, Ocaranza Sánchez, Raymundo, additional, Zueco, Javier, additional, García del Blanco, Bruno, additional, Alonso Briales, Juan Horacio, additional, Sánchez Gila, Joaquín, additional, Vizcaino Arellano, Manuel, additional, Carballo Garrido, Julio, additional, Andraka, Leire, additional, Gómez Jaume, Alfredo, additional, Merino Otermin, Álvaro, additional, Artaiz Urdaci, Miguel, additional, Arellano Serrano, Carlos, additional, García, Eulogio, additional, Unzué, Leire, additional, Arzamendi, Dabit, additional, Mainar, Vicente, additional, Usón, Mariano, additional, Palazuelos Molinero, Jorge, additional, López Palop, Ramón, additional, Bethencourt, Armando, additional, Alegría Barrero, Eduardo, additional, Camacho Freire, Santiago Jesús, additional, Peña, Gonzalo, additional, Vázquez Álvarez, María Eugenia, additional, Muñoz Camacho, Juan Francisco, additional, Ramírez Moreno, Antonio, additional, Larman Tellechea, Mariano, additional, and García de la Borbolla Fernández, Rafael, additional

Published
2023
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10. Registro español de hemodinámica y cardiología intervencionista. XXXII informe oficial de la Asociación de Cardiología Intervencionista de la Sociedad Española de Cardiología (1990-2022)

Author

Jurado-Román, Alfonso, primary, Freixa, Xavier, additional, Cid, Belén, additional, Cruz-González, Ignacio, additional, Sarnago Cebada, Fernando, additional, Baz, José Antonio, additional, Lozano, Íñigo, additional, Sabaté, Manel, additional, Jiménez, Jesús, additional, Íñigo García, Luis Antonio, additional, Subinas Elorriaga, Asier, additional, Berenguer Jofresa, Alberto, additional, Novo García, Enrique, additional, Pérez Vizcayno, María José, additional, Carrillo Suárez, Xavier, additional, Pinar Bermúdez, Eduardo, additional, Calviño Santos, Ramón, additional, Álvarez Antón, Salvador, additional, Trillo Nouche, Ramiro, additional, Ruíz Arroyo, José Ramón, additional, Fernández Cisnal, Agustín, additional, Amat-Santos, Ignacio J., additional, Jerez Valero, Miguel, additional, Rama Merchán, Juan Carlos, additional, Vaquerizo, Beatriz, additional, Tejada Ponce, David, additional, Ruiz Nodar, Juan Miguel, additional, Sánchez Pérez, Ignacio, additional, Tejedor, Paula, additional, Elizaga, Jaime, additional, Jiménez Cabrera, Francisco Manuel, additional, Bullones Ramírez, Juan Antonio, additional, Sánchez Aquino, Rosa, additional, Portero Pérez, María Pilar, additional, Roura, Gerard, additional, Mohandes, Mohsen, additional, Sáez Moreno, Roberto, additional, Avanzas, Pablo, additional, Caballero, Juan, additional, Torres Bosco, Alfonso Miguel, additional, Merchán Herrera, Antonio, additional, Robles Alonso, Javier, additional, Bosa Ojeda, Francisco, additional, García San Román, Koldobika, additional, Agudelo, Victor Hugo, additional, Martin Lorenzo, Pedro, additional, Fernández, Juan Carlos, additional, Pérez de Prado, Armando, additional, Ruiz Quevedo, Valeriano, additional, Cruz González, Ignacio, additional, Moreu Burgos, José, additional, Ruiz García, Juan, additional, Sánchez Burguillos, Francisco José, additional, Núñez Pernas, Daniel, additional, Baello Monge, Pascual, additional, Hernando Marrupe, Lorenzo, additional, Franco Peláez, Juan Antonio, additional, Jurado Román, Alfonso, additional, Pomar Domingo, Francisco, additional, Fuertes Ferre, Georgina, additional, Pimienta González, Raquel, additional, Morales Ponce, Francisco José, additional, Sánchez Recalde, Ángel, additional, Ojeda Pineda, Soledad, additional, Frutos Garcia, Araceli, additional, Millán Segovia, Raúl, additional, Fajardo Molina, Ricardo, additional, Díez Gil, José Luis, additional, Guisado Rasco, Agustín, additional, Gómez Menchero, Antonio Enrique, additional, Bosch, Eduard, additional, Oteo Domínguez, Juan Francisco, additional, Gutiérrez-Barrios, Alejandro, additional, Cascón Pérez, José Domingo, additional, Casanova Sandoval, Juan Manuel, additional, Fernández Portales, Javier, additional, Rivero Crespo, Fernando, additional, Gonzalez Caballero, Eva, additional, Ocaranza Sánchez, Raymundo, additional, Zueco, Javier, additional, García del Blanco, Bruno, additional, Alonso Briales, Juan Horacio, additional, Sánchez Gila, Joaquín, additional, Vizcaino Arellano, Manuel, additional, Carballo Garrido, Julio, additional, Andraka, Leire, additional, Gómez Jaume, Alfredo, additional, Merino Otermin, Álvaro, additional, Artaiz Urdaci, Miguel, additional, Arellano Serrano, Carlos, additional, García, Eulogio, additional, Unzué, Leire, additional, Arzamendi, Dabit, additional, Mainar, Vicente, additional, Usón, Mariano, additional, Palazuelos Molinero, Jorge, additional, López Palop, Ramón, additional, Bethencourt, Armando, additional, Alegría Barrero, Eduardo, additional, Camacho Freire, Santiago Jesús, additional, Peña, Gonzalo, additional, Vázquez Álvarez, María Eugenia, additional, Muñoz Camacho, Juan Francisco, additional, Ramírez Moreno, Antonio, additional, Larman Tellechea, Mariano, additional, and García de la Borbolla Fernández, Rafael, additional

Published
2023
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11. Symptomatic vs. non-symptomatic device-related thrombus after LAAC:a sub-analysis from the multicenter EUROC-DRT registry

Author

Vij, Vivian, Cruz-González, Ignacio, Galea, Roberto, Piayda, Kerstin, Nelles, Dominik, Vogt, Lara, Gloekler, Steffen, Fürholz, Monika, Meier, Bernhard, Räber, Lorenz, O'Hara, Gilles, Arzamendi, Dabit, Agudelo, Victor, Asmarats, Lluis, Freixa, Xavier, Flores-Umanzor, Eduardo, De Backer, Ole, Sondergaard, Lars, Nombela-Franco, Luis, McInerney, Angela, Salinas, Pablo, Korsholm, Kasper, Nielsen-Kudsk, Jens Erik, Afzal, Shazia, Zeus, Tobias, Operhalski, Felix, Schmidt, Boris, Montalescot, Gilles, Guedeney, Paul, Iriart, Xavier, Miton, Noelie, Saw, Jacqueline, Gilhofer, Thomas, Fauchier, Laurent, Veliqi, Egzon, Meincke, Felix, Petri, Nils, Nordbeck, Peter, Gonzalez-Ferreiro, Rocio, Bhatt, Deepak L, Laricchia, Alessandra, Mangieri, Antonio, Omran, Heyder, Schrickel, Jan Wilko, Rodes-Cabau, Josep, Nickenig, Georg, Sievert, Horst, and Sedaghat, Alexander

Abstract

BACKGROUND: Device-related thrombus (DRT) after left atrial appendage closure (LAAC) is associated with adverse outcomes, i.e. ischemic stroke or systemic embolism (SE). Data on predictors of stroke/SE in the context of DRT are limited.AIMS: This study aimed to identify predisposing factors for stroke/SE in DRT patients. In addition, the temporal connection of stroke/SE to DRT diagnosis was analyzed.METHODS: The EUROC-DRT registry included 176 patients, in whom DRT after LAAC were diagnosed. Patients with symptomatic DRT, defined as stroke/SE in the context of DRT diagnosis, were compared against patients with non-symptomatic DRT. Baseline characteristics, anti-thrombotic regimens, device position, and timing of stroke/SE were compared.RESULTS: Stroke/SE occurred in 25/176 (14.2%) patients diagnosed with DRT (symptomatic DRT). Stroke/SE occurred after a median of 198 days (IQR 37-558) after LAAC. In 45.8% stroke/SE occurred within one month before/after DRT diagnosis (DRT-related stroke). Patients with symptomatic DRT had lower left ventricular ejection fractions (50.0 ± 9.1% vs. 54.2 ± 11.0%, p = 0.03) and higher rates of non-paroxysmal atrial fibrillation (84.0% vs. 64.9%, p = 0.06). Other baseline parameters and device positions were not different. Most ischemic events occurred among patients with single antiplatelet therapy (50%), however, stroke/SE was also observed under dual antiplatelet therapy (25%) or oral anticoagulation (20%).CONCLUSION: Stroke/SE are documented in 14.2% and occur both in close temporal relation to the DRT finding and chronologically independently therefrom. Identification of risk factors remains cumbersome, putting all DRT patients at substantial risk for stroke/SE. Further studies are necessary to minimize the risk of DRT and ischemic events.

Published
2023

16. Corrigendum to “Impact of the CHA2DS2-VASc score on late clinical outcomes in patients undergoing left atrial appendage occlusion” [International Journal of Cardiology. 319 (2020) 78–84]

Author

Agudelo, Victor, primary, Millán, Xavier, additional, Li, Chi-Hion, additional, Asmarats, Lluís, additional, Fernandez-Peregrina, Estefania, additional, Santalo, Marcel, additional, Jimenez-Kockar, Marcelo, additional, Gheorghe, Livia, additional, Serra, Antonio, additional, and Arzamendi, Dabit, additional

Published
2022
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23. Device-Related Thrombus After Left Atrial Appendage Closure: Data on Thrombus Characteristics, Treatment Strategies, and Clinical Outcomes From the EUROC-DRT-Registry

Author

Sedaghat, Alexander, primary, Vij, Vivian, additional, Al-Kassou, Baravan, additional, Gloekler, Steffen, additional, Galea, Roberto, additional, Fürholz, Monika, additional, Meier, Bernhard, additional, Valgimigli, Marco, additional, O’Hara, Gilles, additional, Arzamendi, Dabit, additional, Agudelo, Victor, additional, Asmarats, Lluis, additional, Freixa, Xavier, additional, Flores-Umanzor, Eduardo, additional, De Backer, Ole, additional, Søndergaard, Lars, additional, Nombela-Franco, Luis, additional, McInerney, Angela, additional, Korsholm, Kaspar, additional, Nielsen-Kudsk, Jens Erik, additional, Afzal, Shazia, additional, Zeus, Tobias, additional, Operhalski, Felix, additional, Schmidt, Boris, additional, Montalescot, Gilles, additional, Guedeney, Paul, additional, Iriart, Xavier, additional, Miton, Noelie, additional, Saw, Jacqueline, additional, Gilhofer, Thomas, additional, Fauchier, Laurent, additional, Veliqi, Egzon, additional, Meincke, Felix, additional, Petri, Nils, additional, Nordbeck, Peter, additional, Rycerz, Szymon, additional, Ognerubov, Dmitrii, additional, Merkulov, Evgeny, additional, Cruz-González, Ignacio, additional, Gonzalez-Ferreiro, Rocio, additional, Bhatt, Deepak L., additional, Laricchia, Alessandra, additional, Mangieri, Antonio, additional, Omran, Heyder, additional, Schrickel, Jan Wilko, additional, Rodes-Cabau, Josep, additional, and Nickenig, Georg, additional

Published
2021
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24. Oportunidades de emprendimiento en Bogotá originadas por cambios de hábitos de consumo debido a la pandemia

Author

Barrera Agudelo, Victor Fernando, Luna Losada, Sandra Milena, Molano Buenaventura, Juan Pablo, and Rodríguez Peña, Antonio

Subjects
Pandemia, Economía internacional, Pandemic, Comportamiento del consumidor, Entrepreneurship, Modelos de negocio, COVID-19 (Enfermedad) - Crisis financiera, Tendencias, Business models, Emprendimiento, Consumer behavior, Consumption habits, Mercadeo - Tendencias, Consumo (Economía), Desarrollo económico, Hábitos de consumo, Trends
Abstract

Las condiciones de aislamiento y medidas sanitarias tomadas por el gobierno nacional, debido a la pandemia del Covid -19, ha creado unas condiciones y tendencias de consumo nuevas en la población de Bogotá. Esta investigación, y en el presente artículo se quiere presentar la identificación de los cambios de algunos hábitos de consumo en la población de Bogotá, en una muestra de personas entre los 18 y 75 años de edad. De acuerdo con los resultados, los cambios mas notorios, y serán en el largo plazo una actitud típica de los bogotanos, son los hábitos relacionados con el uso de herramientas tecnológicas para realizar actividades como ver películas, teatro, compras en línea, estudio, entre otros. The isolation conditions and sanitary measures taken by the national government, due to the Covid -19 pandemic, have created new conditions and consumption trends in the population of Bogotá. This research, and in this article, we want to present the identification of some of the changes in consumption habits in the population of Bogotá, in a sample of people between 18 and 75 years of age. According to the results, the consumption trend is for those products and services that can be made from virtuality, and that the greatest habit ingrained during these months of confinement has been the use of technological tools to carry out other activities. as it was: watching movies, theater, shopping, payments, and studying. Especialista en Gerencia de Proyectos Especialización

Published
2020

31. An approach for explaining chemical transformations

Author

López-Agudelo, Victor A., Barragán, Daniel, and Parra, Wilson

Subjects
reactivity, molecular modeling, energy minimization, ComputingMilieux_COMPUTERSANDEDUCATION
Abstract

A methodology is proposed for explaining one of the central questions in the teaching of general chemistry courses to freshman students: why do chemical transformations occur? The answer to this question is based on thermodynamics but we propose arriving at an answer in a more intuitive way by using computational tools in a bid to increase the motivation of students for learning chemistry.

Published
2013

33. Sensitivity Analysis of In Silico Fluid Simulations to Predict Thrombus Formation after Left Atrial Appendage Occlusion

Author

Etelvino Silva, Maria Isabel Pons, Xabier Morales, Andy L. Olivares, Victor Agudelo, Oscar Camara, Xavier Freixa, Jérôme Noailly, Marta Nuñez-Garcia, Dabit Arzamendi, Jordi Mill, [Mill,J, Olivares,AL, Pons,MI, Morales,X, Noailly,J, Camara,O] BCN-MedTech, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Spain. [Agudelo,V, Arzamendi,D] Department of Cardiology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. [Silva,E] Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Grupo GADICOR, Hospital Universitario Puerta del Mar, Universidad de Cádiz, Cádiz, Spain. [Nuñez-Garcia,M] Electrophysiology and Heart Modeling Institute (IHU Liryc), Pessac, France. [Nuñez-Garcia,M] Centre de Recherche Cardio-Thoracique de Bordeaux, Université de Bordeaux, Bordeaux, France. [Freixa,X] Department of Cardiology, Hospital Clínic, Barcelona, Spain., This work was supported by the Spanish Ministry of Science, Innovation and Universities under the Retos I+D Programme (RTI2018-101193-B-I00), the Maria de Maeztu Units of Excellence Programme (MDM-2015-0502), the Spanish Ministry of Economy and Competitiveness under the Programme for the Formation of Doctors (PRE2018-084062), and MINECO (RYC-2015-18888). Addi tionally, this work was supported by the H2020 EU SimCardioTest project (Digital transformation in Health and Care SC1-DTH-06-2020, grant agreement No. 101016496)., [Mill, Jordi] Univ Pompeu Fabra, BCN MedTech, Dept Informat & Commun Technol, Barcelona 08018, Spain, [Olivares, Andy L.] Univ Pompeu Fabra, BCN MedTech, Dept Informat & Commun Technol, Barcelona 08018, Spain, [Pons, Maria Isabel] Univ Pompeu Fabra, BCN MedTech, Dept Informat & Commun Technol, Barcelona 08018, Spain, [Morales, Xabier] Univ Pompeu Fabra, BCN MedTech, Dept Informat & Commun Technol, Barcelona 08018, Spain, [Noailly, Jerome] Univ Pompeu Fabra, BCN MedTech, Dept Informat & Commun Technol, Barcelona 08018, Spain, [Camara, Oscar] Univ Pompeu Fabra, BCN MedTech, Dept Informat & Commun Technol, Barcelona 08018, Spain, [Agudelo, Victor] Hosp Santa Creu & Sant Pau, Dept Cardiol, Barcelona 08025, Spain, [Arzamendi, Dabit] Hosp Santa Creu & Sant Pau, Dept Cardiol, Barcelona 08025, Spain, [Silva, Etelvino] Univ Cadiz, Hosp Univ Puerta del Mar, Inst Invest & Innovac Biomed Cadiz INiBICA, Grp GADICOR, Cadiz 11009, Spain, [Nunez-Garcia, Marta] Electrophysiol & Heart Modeling Inst IHU Liryc, F-33600 Pessac, France, [Nunez-Garcia, Marta] Univ Bordeaux, U1045, Ctr Rech Cardiothorac Bordeaux, F-33076 Bordeaux, France, [Freixa, Xavier] Hosp Clin Barcelona, Dept Cardiol, Barcelona 08036, Spain, Spanish Ministry of Science, Innovation and Universities, Maria de Maeztu Units of Excellence Programme, Spanish Ministry of Economy and Competitiveness, MINECO, and H2020 EU SimCardioTest project (Digital transformation in Health and Care SC1-DTH-06-2020)

Subjects
Anatomy::Cardiovascular System::Heart::Heart Valves::Mitral Valve [Medical Subject Headings], medicine.medical_treatment, Hemodynamics, Computational fluid dynamics, Device-related thrombosis, Fibrilación auricular, left atrium, Pulmonary vein, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Atrios cardíacos, sensitivity analysis, Mitral valve, boundary conditions, Diseases::Cardiovascular Diseases::Vascular Diseases::Embolism and Thrombosis::Thrombosis [Medical Subject Headings], Anatomy::Cardiovascular System::Blood Vessels::Veins::Pulmonary Veins [Medical Subject Headings], Computer Science (miscellaneous), Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Hematologic Agents::Anticoagulants [Medical Subject Headings], Cardiac cycle, Device-related thrombus, Atrial fibrillation, Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Cardiovascular Physiological Phenomena::Hemodynamics [Medical Subject Headings], medicine.anatomical_structure, Left atrium, Anatomy::Cardiovascular System::Heart::Heart Atria::Atrial Appendage [Medical Subject Headings], dynamic mesh, cardiovascular system, Cardiology, Enfermedades cardiovasculares, Sensitivity analysis, Risk, Phenomena and Processes::Physical Phenomena::Geological Phenomena::Oceans and Seas::Bays [Medical Subject Headings], medicine.medical_specialty, Closure, Blood-flow, left atrial appendage, Left atrial appendage, General Mathematics, computational fluid dynamics, Diseases::Cardiovascular Diseases::Heart Diseases::Arrhythmias, Cardiac::Atrial Fibrillation [Medical Subject Headings], Left atrial appendage occlusion, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Equipment and Supplies::Surgical Equipment::Surgical Mesh [Medical Subject Headings], Trombosis, Internal medicine, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Follow-Up Studies [Medical Subject Headings], QA1-939, medicine, cardiovascular diseases, Sensitivity (control systems), Thrombus, Dynamic mesh, Engineering (miscellaneous), Boundary conditions, Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology, Social::Group Processes::Consensus [Medical Subject Headings], business.industry, medicine.disease, Hidrodinámica, device-related thrombus, Fibrillation, business, Apéndice atrial, Mathematics
Abstract

Atrial fibrillation (AF) is nowadays the most common human arrhythmia and it is considered a marker of an increased risk of embolic stroke. It is known that 99% of AF-related thrombi are generated in the left atrial appendage (LAA), an anatomical structure located within the left atrium (LA). Left atrial appendage occlusion (LAAO) has become a good alternative for nonvalvular AF patients with contraindications to anticoagulants. However, there is a non-negligible number of device-related thrombus (DRT) events, created next to the device surface. In silico fluid simulations can be a powerful tool to better understand the relation between LA anatomy, haemodynamics, and the process of thrombus formation. Despite the increasing literature in LA fluid modelling, a consensus has not been reached yet in the community on the optimal modelling choices and boundary conditions for generating realistic simulations. In this line, we have performed a sensitivity analysis of several boundary conditions scenarios, varying inlet/outlet and LA wall movement configurations, using patient-specific imaging data of six LAAO patients (three of them with DRT at follow-up). Mesh and cardiac cycle convergence were also analysed. The boundary conditions scenario that better predicted DRT cases had echocardiography-based velocities at the mitral valve outlet, a generic pressure wave from an AF patient at the pulmonary vein inlets, and a dynamic mesh approach for LA wall deformation, emphasizing the need for patient-specific data for realistic simulations. The obtained promising results need to be further validated with larger cohorts, ideally with ground truth data, but they already offer unique insights on thrombogenic risk in the left atria. This work was supported by the Spanish Ministry of Science, Innovation and Universities under the Retos I+D Programme (RTI2018-101193-B-I00), the Maria de Maeztu Units of Excellence Programme (MDM-2015-0502), the Spanish Ministry of Economy and Competitiveness under the Programme for the Formation of Doctors (PRE2018-084062), and MINECO (RYC-2015-18888). Additionally, this work was supported by the H2020 EU SimCardioTest project (Digital transformation in Health and Care SC1-DTH-06-2020; grant agreement No. 101016496).

Published
2021

34. Impact of the CHA 2 DS 2 -VASc score on late clinical outcomes in patients undergoing left atrial appendage occlusion.

Author

Agudelo V, Millán X, Li CH, Asmarats L, Fernández-Peregrina E, Santaló M, Jimenez-Kockar M, Gheorghe L, Serra A, and Arzamendi D

Subjects
Anticoagulants, Atrial Fibrillation diagnosis, Atrial Fibrillation surgery, Humans, Risk Assessment, Risk Factors, Stroke epidemiology, Stroke prevention & control, Thromboembolism epidemiology, Thromboembolism etiology, Thromboembolism prevention & control, Atrial Appendage diagnostic imaging, Atrial Appendage surgery
Abstract

Background: Left atrial appendage occlusion (LAAO) is an accepted strategy for cardioembolic events prevention in patients with non-valvular atrial fibrillation (AF) unsuitable for anticoagulation. However, uncertainties persist regarding the benefit of LAAO in highly-comorbid patients. The aim of this study was to assess the impact of the CHA 2 DS 2 -VASc score beyond thromboembolic risk in predicting clinical outcomes in patients undergoing LAAO., Methods: 160 patients who underwent LAAO were included and categorized into two groups according to their stroke risk (89 with CHA 2 DS 2 -VASc >4 vs. 71 with lower risk). The coprimary endpoints were death and stroke at follow-up. Thromboembolic and bleeding events were compared to those predicted from CHA 2 DS 2 -VASc and HAS-BLED scores., Results: Over a median follow-up of 679 days, CHA 2 DS 2 -VASc >4 was associated with increased all-cause mortality compared with patients with lower thromboembolic risk (HR: 3.23; 95% CI: 1.28-8.19; p < 0.001). However, the rates of stroke after LAAO were not significantly different between risk groups. The observed annual rates of stroke and major bleeding were lower than predicted., Conclusions: Despite increased long-term mortality in patients with CHA 2 DS 2 -VASc >4, LAAO remains beneficial in reducing stroke and bleeding events in high-risk AF patients unsuitable for anticoagulation., (Copyright © 2020 Elsevier B.V. All rights reserved.)

Published
2020
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