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Eucalyptus camaldulensis is a multifunctional tree and is globally used for the reclamation of problematic lands. Eucalyptus camaldulensis is prone to attack by a number of pathogens, but the most important threat is the Fusarium wilt (Fusarium oxysporum). Keeping in view the importance of E. camaldulensis and to manage this disease, five plant activators, i.e., salicylic acid (C7H6O3), benzoic acid (C7H6O2), citric acid (C6H8O7), dipotassium phosphate (K2HPO4), monopotassium phosphate (KH2PO4) and nutritional mixture namely Compound (NPK) and nutriotop (Fe, Zn, Cu, B, Mn) were evaluated in the Fusarium infested field under RCBD in the Research Area, Department of Forestry and Range Management, University of Agriculture, Faisalabad (UAF). Among plant activators, salicylic acid and a combination of compound + nutriotop exhibited the lowest disease incidence and enhanced fresh and dry weight of leaves compared to other treatments and control. Results of the environmental study indicated maximum disease incidence between 35-40 °C (max. T), 6-25 °C (mini. T), 70-80% relative humidity and 1.5-2.5 km/h wind speed while pan evaporation expressed weak correlation with disease development. It was concluded that Fusarium wilt of Eucalyptus camaldulensis could be managed through activation of the basal defense system of the host plant with provision of salicylic acid and balanced nutrition by considering environmental factors. Recent exploration is expected to be helpful for future research efforts on epidemiology and ecologically sound intervention of Fusarium wilt of Eucalyptus camaldulensis.

Multidrug-resistant wound infections are a global health threat and a leading cause of death, persisting despite available treatments due to antibiotic resistance, biofilms, and ineffective drug delivery systems. The aim of this study is to (i) formulate an innovative nano-drug delivery system (NDDS) based on a Carbopol nanoemulgel (NEG) co-loaded with neomycin-silver/zinc oxide nanocomposite (NC) that could fight clinical MDR and treat biofilm-forming wound pathogens through topical application, and (ii) assess its in vivo wound-healing potential. The silver/zinc oxide (Ag/ZnO) NC was synthesized by co-inoculating the metabolites of Aspergillus welwitschiae and Meyerozyma guilliermondii. The synthesized NC was then conjugated with neomycin and loaded into a Carbopol NEG for efficient topical delivery. The resulting Neo-Ag/ZnO NEG was characterized physicochemically (e.g., UV-visible [UV-Vis] spectrophotometry, field emission scanning electron microscopy, X-ray diffraction, and Fourier transform infrared [FTIR] spectroscopy), biologically (e.g., in vitro antimicrobial, antibiofilm, and hemolytic activities), and pharmacologically (e.g., drug content, ex vivo drug release behavior, and in vivo wound-healing potential). The physicochemical analysis confirmed the successful mycosynthesis of the Carbopol NEG-loaded Neo-Ag/ZnO NC. SEM depicted a crystalline polyhedral shape of the small NC (average particle size of 38 nm). FTIR studies showed a slight interaction with the drug and other bioactive moieties in the Carbopol NEG. The Neo content in the Carbopol NEG was as high as 98%, and a maximum release of 81% for Neo, Ag, and ZnO ions was noticed after 12 h. The NDDS appeared hemocompatible and displayed a minimal inhibition concentration of 0.002 µg/mL with the greatest antimicrobial potential against S. aureus (an inhibition zone of 46 mm) compared to other tested wound microbes (p < 0.05). Statistically significant wound-healing activity was found for NDDS (p = 0.0001) in comparison to the control at a concentration of 100 mg/mL. The results showed that this newly developed Carbopol NEG-loaded neo-Ag/ZnO NC appeared promising for controlling resistant skin infections and boosting wound regeneration.

In present investigation, we elucidated the structural, elastic, optical, mechanical, electronic, and thermodynamics properties of AB2 (A = Hf, Zr, and BCo, W) laves phases via first principles scheme of density functional hypothesis. The effect of pressure on various physical aspects up to 100 GPa accounted to this research and found significant changes at different pressures. The results we obtained for the present enquiry have been quantified with the previous research of relevant work and relatively better performance is obtained. The cell parameters as well as unit cell volume are found to be decreased with applied pressure since the interatomic distances of atoms became shorter with pressure. The negative formation enthalpy ensures the chemical and thermodynamical stability of the studied phases. Using Born approximation criterion the mechanical stability has been verified where the phase transition of AB2 (A = Hf, and BCo, W) and AB2 (A = Zr and BCo, W) has been observed after 20 GPa and 40 GPa respectively. It was observed that elastic moduli of AB2 (A = Hf, Zr, and BCo, W) increases with increasing pressure. The higher C11 values among three elastic moduli show higher resistance to linear compression for the current study which is even better than the previously reported result. Mechanical performance has been measured in terms of shear modulus (G), bulk modulus (B), and Young modulus (E) using Vigot-Reuss-Hill method. The estimated data shown pressure rising G, B, and E values indicates dominating stiffness properties under applied stress which ensure their industrial applications. The increased nature of machinable index of all these phases unsure their huge applications in cutting tool geometry, cutting fluids and and plastic strain. The Poisson and Pugh ratio analysis suggests that at zero pressure only the phase HfCo2 shows brittle nature and the other phases AB2 (A = Zr, and BCo, W) show ductile nature from 0 to 100 GPa. The electronic properties investigated through density of state (DOS) calculations revels the metallic characteristics of the titled phases. Decrease in total DOS at high pressure is observed for all the phases. Under pressure it was found that optical indices like absorption coefficient, conductivity, loss function, reflectivity, and dielectric functions are gradually shifted toward higher energies confirming that these materials can be used solar cells to reduce solar heating, and in UV light-based device for high absorption. Higher Debye temperature, thermal conductivity and melting temperature of AB2 (A = Hf, Zr, and BCo, W) are found at ambient condition and these parameters are increasing with increasing pressure which ensure the high temperature industrial applications of these phases. Among four laves phases, relatively higher mechanical, optical, and thermodynamic performance is obtained for HfW2 compound.

Research has demonstrated an advantage for the processing of self-associated stimuli for various mental functions (Sui & Humphreys, 2017). However, relatively little is known about whether prioritization exists for internal representations (Yin et al., 2019). In the current study, we first asked participants to associate social – labels ('self', ‘friend’, ‘stranger’) with arbitrary geometrical shapes (triangle, quadrilateral, and pentagon) (Sui et al., 2012) and then tested them for the maintenance of one or more features (shape, location, or a combination) of the target stimuli during a delayed match – to – sample task. In line with our expectations, our participants indeed showed a distinct advantage for self-associated stimuli for maintaining single features (identity, location) and a combination (shape & location). Our findings align with the proposal that self-reference may aid in binding information in working memory (Sui & Humphreys, 2015).

Here we investigated the effects of Ce and Mo doping on hydrothermally synthesized bismuth vanadate BiVO4 nanoparticles (NPs). The existence of monoclinic scheelite and tetragonal zircon phases of NPs was validated from Rietveld refinement of the powdered X-ray diffraction, room temperature Raman, and Fourier-transform infrared spectroscopy. The co-doping of Bi and V sites with respective Ce and Mo dopants in a mixed tetragonal zircon and monoclinic scheelite phases of BiVO4 lattice was corroborated from high-resolution transmission electron microscopy and X-ray photoelectron spectroscopy. The photoluminescence measurements revealed enhancement of photo-generated carrier recombination in (Ce, Mo) co-doped BiVO4 NPs which may have hampered its photocatalytic efficiency in degrading the methylene blue dye. The simulations based on Hubbard U corrected density functional theory (DFT+U) suggest that Mo and Ce co-doping introduced deep impurity states which may have facilitated the photo-generated carrier recombination detrimental to photocatalytic performance. The UV-vis diffuse reflectance measurements provided evidence for the presence of these defect states. In summary, this work may have presented a comprehensive experimental analysis of (Ce, Mo) doped BiVO4 supported by DFT simulations.