1. Minor increase of endtidal CO2 during sevoflurane-induced malignant hyperthermia.
- Author
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Bonciu M, de la Chapelle A, Delpech H, Depret T, Krivosic-Horber R, and Aimé MR
- Subjects
- Anesthetics, Intravenous administration & dosage, Biopsy methods, Body Temperature drug effects, Child, Cholesteatoma surgery, Creatine Kinase blood, Crystalloid Solutions, Heart Rate drug effects, Humans, Isotonic Solutions administration & dosage, Male, Malignant Hyperthermia diagnosis, Muscle Contraction drug effects, Myoglobin blood, Organ Culture Techniques, Parents, Piperidines administration & dosage, Quadriceps Muscle pathology, Remifentanil, Sevoflurane, Tympanoplasty methods, Anesthetics, Inhalation adverse effects, Carbon Dioxide analysis, Malignant Hyperthermia etiology, Malignant Hyperthermia therapy, Methyl Ethers adverse effects, Respiration, Artificial methods
- Abstract
Malignant hyperthermia (MH) in a pediatric patient during sevoflurane anesthesia with only a minor rise of endtidal CO(2) is described. MH was considered because of increased rectal temperature. The outcome was favorable after the initiation of a few simple measures (increased minute ventilation, cessation of sevoflurane). As recommended by the regional MH Reference Center, dantrolene was not used. In vitro contracture tests were performed on muscle biopsies from both parents. A strong contracture in response to halothane confirmed the father's MH susceptibility, thereby according a high probability of an MH episode in his son.
- Published
- 2007
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