81 results on '"Aiming Yan"'
Search Results
2. Impact of cardiac factors on central airway anatomical parameters in patients undergoing lung mass surgery
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Yingding Ruan, Hongsheng Xue, Wenjun Cao, Jianwei Han, Aiming Yang, Jincheng Xu, and Ting Zhang
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Cardiac factors ,Central airway parameters ,Lung mass surgery ,Computed tomography ,Multivariate linear regression analysis ,Surgery ,RD1-811 ,Anesthesiology ,RD78.3-87.3 - Abstract
Abstract Background The correlation between central airway anatomical parameters and demographic factors, such as sex, age, weight, height, body mass index (BMI), and cardiac factors, remains unclear. This study examined the correlation between these factors and central airway anatomical parameters in adult patients. Methods All consecutive patients who underwent lung mass surgery at our hospital between December 2020 and December 2023 were included in this study. DeepInsight software was used to analyze high-resolution chest computed tomography (HRCT) images and to measure various central airway anatomical parameters, including tracheal diameter (TD), tracheal length (TL), left main bronchus diameter (LBD), left main bronchus length (LBL), right main bronchus diameter (RBD), right main bronchus length (RBL), and subcarinal angle (SCA). A multivariate linear regression analysis was performed to evaluate the independent effects of sex, age, weight, height, BMI, left atrial diameter, and diastolic left ventricular internal diameter (LVIDd) on these anatomical parameters. Results Among the 391 patients included in this study, all were over 18 years old, with 192 male and 199 female. The multivariate linear regression analysis indicated that in male patients with lung masses, TD exhibited a negative correlation with age (β = − 0.032, P = 0.015) and a positive correlation with height (β = 0.099, P more...
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- 2025
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3. Prognostic impact of the newly revised IASLC proposed grading system for invasive lung adenocarcinoma: a systematic review and meta-analysis
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Yingding Ruan, Wenjun Cao, Jianwei Han, Aiming Yang, Jincheng Xu, and Ting Zhang
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Lung adenocarcinoma ,IASLC grading system ,Prognosis ,Systematic review ,Meta-analysis ,Surgery ,RD1-811 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background This study aimed to evaluate the prognostic value of the newly revised International Association for the Study of Lung Cancer (IASLC) grading system (2020) on the 5-year overall survival (OS) and recurrence-free survival (RFS) in patients with lung adenocarcinoma (LADC). Methods Clinical studies that investigated the prognostic value of revised IASLC staging system in patients with LADC were retrieved from the PubMed, Web of Science, ScienceDirect, and Cochrane Library databases. This study was conducted in accordance to the 2020 Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and checklists. Results Based on inclusion and exclusion criteria, we included 12 studies for analysis. The grade of LADC was assessed by revised IASLC system, which included three grades. Compared to Grade 3 LADC, grade 1 (total [95% CI]: 1.38 [1.19, 1.60]) and grade 2 (total [95% CI]: 1.29 [1.15, 1.44]) LADC had higher 5-year OS rates. Similarly, Grade 1 (total [95% CI]: 1.76 [1.42, 2.18]) and Grade 2 (total [95% CI]: 1.51 [1.28, 1.77]) had higher 5-year RFS rates Grade 3 LADC. However, 5-year OS and RFS had no significant difference between Grade 1 and Grade 2 patients. Conclusion This systematic review and meta-analysis provides evidence that the newly revised IASLC grading system is significantly associated with the prognosis of patients with LADC, where Grade 3 indicated unfavorable prognosis. more...
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- 2024
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4. Association between oxidative balance score and gallstone disease: a population-based study from NHANES
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Mengmeng Zhang and Aiming Yang
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oxidative balance score ,diet ,lifestyle ,gallstones ,NHANES ,Nutrition. Foods and food supply ,TX341-641 - Abstract
BackgroundOxidative stress has been reported to participant in the pathogenesis of gallstones. Oxidative balance score (OBS) represents pro-oxidant and antioxidant exposures to diet and lifestyle, closely associated with multiple metabolic disorders. However, the relationship between OBS and gallstones remains unclear.MethodsThis study analyzed cross-sectional data from the National Health and Nutrition Examination Survey (NHANES) 2017–2020. OBS was calculated based on the 24-h recall interviews or questionnaires. We used weighted logistic regression, restricted cubic splines (RCS), weighted quantile sum (WQS) regression and the Bayesian kernel machine regression (BKMR) model to identify the relationship between OBS and gallstones. Subgroup analysis and sensitivity analysis were used to explore potential heterogeneity and stability of the results. Mediation analysis was performed to assess the mediating effects of serum lipid in the association between OBS and gallstones.ResultsA total of 7,618 participants were finally included in this study. Weighted logistics regression showed that total OBS was associated with gallstones risk (OR = 0.98, p = 0.03), particularly in individuals who were under 60 years old, Hispanic, educated below high school, non-smokers, had hypertension or malignancy. Dietary and lifestyle OBS independently contribute to the protection against gallstones. RCS analysis indicated a non-linear relationship between OBS and gallstones (p = 0.03). WQS and BKMR model identified that BMI, vitamin E, vitamin B6, magnesium and carotene played relatively important role among 20 components. Mediation analysis showed serum TG and HDL as mediators of the association between OBS and gallstones.ConclusionHigher OBS or increased oxidative balance are positively associated with reduction of gallstone risk. This findings provide valuable insights for surveillance and interventions targeting for antioxidant-rich diet and lifestyle for gallstone disease. more...
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- 2025
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5. Impact of preoperative inflammatory indices and postoperative pneumonia on postoperative atrial fibrillation in patients with non-small cell lung cancer: a retrospective study
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Yingding Ruan, Jianwei Han, Aiming Yang, Qingguo Ding, and Ting Zhang
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Non-small cell lung cancer ,Pulmonary surgery ,Postoperative atrial fibrillation ,Preoperative inflammatory indices ,Postoperative pneumonia ,Diseases of the respiratory system ,RC705-779 - Abstract
Abstract Background This study aimed to evaluate the impact of preoperative inflammatory indices and postoperative pneumonia (POP) on postoperative atrial fibrillation (POAF) in non–small cell lung cancer (NSCLC) patients. Methods All consecutive patients who underwent pulmonary resection at our hospital (January 2016-October 2019) were enrolled. Preoperative inflammatory indices, demographic data, surgical details, and postoperative conditions were analyzed. Univariate and multivariate analyses of risk factors associated with POAF were also conducted. Results Among the 382 patients included in the study, 32 (8.38%) developed POAF. Compared to non-POAF patients, POAF patients had greater incidence of POP (P = 0.09). Approximately 31 patients (96.9%) developed atrial fibrillation within three days after surgery. The POAF group had a significantly greater mean age (68.94 years) than did the non-POAF group (63 years) (P = 0.002). Additionally, compared to non-POAF patients, POAF patients exhibited an increased number of resected mediastinal lymph nodes (P more...
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- 2024
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6. Observation of moiré excitons in WSe2/WS2 heterostructure superlattices
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Chenhao Jin, Emma C. Regan, Aiming Yan, M. Iqbal Bakti Utama, Danqing Wang, Sihan Zhao, Ying Qin, Sijie Yang, Zhiren Zheng, Shenyang Shi, Kenji Watanabe, Takashi Taniguchi, Sefaattin Tongay, Alex Zettl, and Feng Wang more...
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Condensed Matter::Quantum Gases ,Physics ,Multidisciplinary ,Condensed Matter - Mesoscale and Nanoscale Physics ,Hubbard model ,Condensed matter physics ,General Science & Technology ,Condensed Matter::Other ,Mott insulator ,Superlattice ,Exciton ,Heterojunction ,02 engineering and technology ,Condensed Matter::Mesoscopic Systems and Quantum Hall Effect ,021001 nanoscience & nanotechnology ,01 natural sciences ,Condensed Matter::Materials Science ,Excited state ,cond-mat.mes-hall ,MD Multidisciplinary ,0103 physical sciences ,010306 general physics ,0210 nano-technology ,Electronic band structure ,Bilayer graphene - Abstract
Moiré superlattices enable the generation of new quantum phenomena in two-dimensional heterostructures, in which the interactions between the atomically thin layers qualitatively change the electronic band structure of the superlattice. For example, mini-Dirac points, tunable Mott insulator states and the Hofstadter butterfly pattern can emerge in different types of graphene/boron nitride moiré superlattices, whereas correlated insulating states and superconductivity have been reported in twisted bilayer graphene moiré superlattices1-12. In addition to their pronounced effects on single-particle states, moiré superlattices have recently been predicted to host excited states such as moiré exciton bands13-15. Here we report the observation of moiré superlattice exciton states in tungsten diselenide/tungsten disulfide (WSe2/WS2) heterostructures in which the layers are closely aligned. These moiré exciton states manifest as multiple emergent peaks around the original WSe2 A exciton resonance in the absorption spectra, and they exhibit gate dependences that are distinct from that of the A exciton in WSe2 monolayers and in WSe2/WS2 heterostructures with large twist angles. These phenomena can be described by a theoretical model in which the periodic moiré potential is much stronger than the exciton kinetic energy and generates multiple flat exciton minibands. The moiré exciton bands provide an attractive platform from which to explore and control excited states of matter, such as topological excitons and a correlated exciton Hubbard model, in transition-metal dichalcogenides. more...
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- 2019
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7. Plasma campesterol and ABCG5/ABCG8 gene loci on the risk of cholelithiasis and cholecystitis: evidence from Mendelian randomization and colocalization analyses
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Jiarui Mi, Qingwei Jiang, Zhengwei Qi, Zhengye Liu, Xiaoyin Bai, Xia Zheng, Jiaguo Wu, Yanfei Fang, Aiming Yang, and Haotian Chen
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Cholelithiasis ,Cholecystitis ,Campesterol ,Mendelian randomization ,Colocalization analysis ,Risk factor ,Medicine ,Genetics ,QH426-470 - Abstract
Abstract The causal relationships between plasma metabolites and cholelithiasis/cholecystitis risks remain elusive. Using two-sample Mendelian randomization, we found that genetic proxied plasma campesterol level showed negative correlation with the risk of both cholelithiasis and cholecystitis. Furthermore, the increased risk of cholelithiasis is correlating with the increased level of plasma campesterol. Lastly, genetic colocalization study showed that the leading SNP, rs4299376, which residing at the ABCG5/ABCG8 gene loci, was shared by plasma campesterol level and cholelithiasis, indicating that the aberrant transportation of plant sterol/cholesterol from the blood stream to the bile duct/gut lumen might be the key in preventing cholesterol gallstone formation. more...
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- 2024
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8. Ultra-durable cell-free bioactive hydrogel with fast shape memory and on-demand drug release for cartilage regeneration
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Yuxuan Yang, Xiaodan Zhao, Shuang Wang, Yanfeng Zhang, Aiming Yang, Yilong Cheng, and Xuesi Chen
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Science - Abstract
Abstract Osteoarthritis is a worldwide prevalent disease that imposes a significant socioeconomic burden on individuals and healthcare systems. Achieving cartilage regeneration in patients with osteoarthritis remains challenging clinically. In this work, we construct a multiple hydrogen-bond crosslinked hydrogel loaded with tannic acid and Kartogenin by polyaddition reaction as a cell-free scaffold for in vivo cartilage regeneration, which features ultra-durable mechanical properties and stage-dependent drug release behavior. We demonstrate that the hydrogel can withstand 28000 loading-unloading mechanical cycles and exhibits fast shape memory at body temperature (30 s) with the potential for minimally invasive surgery. We find that the hydrogel can also alleviate the inflammatory reaction and regulate oxidative stress in situ to establish a microenvironment conducive to healing. We show that the sequential release of tannic acid and Kartogenin can promote the migration of bone marrow mesenchymal stem cells into the hydrogel scaffold, followed by the induction of chondrocyte differentiation, thus leading to full-thickness cartilage regeneration in vivo. This work may provide a promising solution to address the problem of cartilage regeneration. more...
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- 2023
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9. Endoscopic and histopathological hints on infections in patients of common variable immunodeficiency disorder with gastrointestinal symptoms
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Yang Chen, Yan You, Ji Li, Aiming Yang, Weixun Zhou, and Xiaoqing Li
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Common variable immunodeficiency disorder ,Endoscopy ,Histopathology ,Infection ,Nodular lymphoid hyperplasia ,Diseases of the digestive system. Gastroenterology ,RC799-869 - Abstract
Abstract Background and aims Common variable immunodeficiency disorder (CVID) patients may have gastrointestinal (GI) involvement and suffer from infections, which are poorly understood. This study aimed to evaluate the clinical, endoscopic, and histopathological features of CVID patients with GI symptoms and determine their correlation with infections. Methods We performed a retrospective study on 21 CVID patients with GI symptoms who underwent endoscopic examination in Peking Union Medical College Hospital from 2000 to 2020. The clinical, infectious, endoscopic, and histopathological features were reassessed. Results Chronic diarrhea was the most prevalent GI symptom, observed in 95.2% of our CVID cohort. Over 85% of patients had low body weight and malabsorption. Small bowel villous atrophy was found in 90.5% of patients under endoscopy and mostly confirmed by histopathology. GI infections were identified in 9 (42.9%) patients. Of these, 7 patients with diffuse and obvious nodular lymphoid hyperplasia (NLH) of small bowel under endoscopy had significantly higher infection rate (85.7% vs 21.4%, p more...
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- 2023
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10. Cognition of abdominal pain and abdominal discomfort in Chinese patients with irritable bowel syndrome with diarrhea
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Jia Lu, Yang Chen, Lili Shi, Xiaoqing Li, Guijun Fei, Ji Li, Aiming Yang, and Xiucai Fang
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Irritable bowel syndrome with diarrhea ,Abdominal pain ,Abdominal discomfort ,Cognition ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Abstract Background In Asia, the proportion of patients with irritable bowel syndrome (IBS) with abdominal discomfort alone is significantly higher than that in western countries. The purposes of this study are to understand the cognition of abdominal pain and abdominal discomfort in Chinese patients with IBS and to compare the clinical characteristics of patients with abdominal pain alone and with abdominal discomfort alone. Methods Patients with IBS with diarrhea (IBS-D) who met the Rome III diagnostic criteria and had episodes of at least one day/week were consecutively enrolled. The cognition of abdominal pain and abdominal discomfort were investigated through face-to-face unstructured interview. Patients were divided into a pain group and a discomfort group according to the cognition interviews, then the characteristics and severity of symptoms (IBS symptom severity scale, IBS-SSS), IBS quality of life (IBS-QOL) and psychological state were compared between groups. Results A total of 88 patients with IBS-D were enrolled. Most of the patients with self-reported abdominal pain described their pain as spasm/cramping; patients with self-reported abdominal discomfort had as many as 24 different descriptions of discomfort. Most patients having abdominal pain and discomfort could accurately distinguish the two symptoms. The degree of abdominal pain in the pain group was higher than abdominal discomfort in the discomfort group (P = 0.002). There was no significant difference in IBS-SSS, extra-intestinal pain, IBS-QOL, and psychological state between the two groups. Conclusions For Chinese patients with IBS-D, abdominal pain and abdominal discomfort are two different symptoms, but they have similar clinical features. Trial registration ChiCTR, ChiCTR1900028082. Registered 11 December 2019 - Retrospectively registered, http://www.chictr.org.cn . more...
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- 2023
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11. Spontaneous twisting of a collapsed carbon nanotube
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Eduardo Gracia-Espino, Alex Zettl, Steven G. Louie, Sinisa Coh, Thomas Wågberg, Marvin L. Cohen, Gabriel Dunn, Hamid Reza Barzegar, Claudia Ojeda-Aristizabal, and Aiming Yan
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Nanotube ,Microscope ,Materials science ,Nanotechnology ,02 engineering and technology ,Carbon nanotube ,Condensed Matter::Mesoscopic Systems and Quantum Hall Effect ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,Atomic and Molecular Physics, and Optics ,law.invention ,In situ transmission electron microscopy ,Condensed Matter::Materials Science ,Electron diffraction ,law ,0103 physical sciences ,General Materials Science ,Electrical and Electronic Engineering ,010306 general physics ,0210 nano-technology ,Graphene nanoribbons - Abstract
We study the collapsing and subsequent spontaneous twisting of a carbon nanotube by in situ transmission electron microscopy (TEM). A custom-sized nanotube is first created in the microscope by sel ... more...
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- 2017
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12. Cuproptosis in stroke: focusing on pathogenesis and treatment
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Liwei Xing, Zhifeng Wang, Zhihui Hao, Pan Pan, Aiming Yang, and Jian Wang
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stroke ,cuproptosis ,pathogenesis ,treatment ,mechanism ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Annually, more than 15 million people worldwide suffer from stroke, a condition linked to high mortality and disability rates. This disease significantly affects daily life, impairing everyday functioning, executive function, and cognition. Moreover, stroke severely restricts patients’ ability to perform daily activities, diminishing their overall quality of life. Recent scientific studies have identified cuproptosis, a newly discovered form of cell death, as a key factor in stroke development. However, the role of cuproptosis in stroke remains unclear to researchers. Therefore, it is crucial to investigate the mechanisms of cuproptosis in stroke’s pathogenesis. This review examines the physiological role of copper, the characteristics and mechanisms of cuproptosis, the differences and similarities between cuproptosis and other cell death types, and the pathophysiology of cuproptosis in stroke, focusing on mitochondrial dysfunction and immune infiltration. Further research is necessary to understand the relationship between previous strokes and cuproptosis and to clarify the mechanisms behind these associations. more...
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- 2024
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13. Observation of moiré excitons in WSe
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Chenhao, Jin, Emma C, Regan, Aiming, Yan, M, Iqbal Bakti Utama, Danqing, Wang, Sihan, Zhao, Ying, Qin, Sijie, Yang, Zhiren, Zheng, Shenyang, Shi, Kenji, Watanabe, Takashi, Taniguchi, Sefaattin, Tongay, Alex, Zettl, and Feng, Wang more...
- Abstract
Moiré superlattices enable the generation of new quantum phenomena in two-dimensional heterostructures, in which the interactions between the atomically thin layers qualitatively change the electronic band structure of the superlattice. For example, mini-Dirac points, tunable Mott insulator states and the Hofstadter butterfly pattern can emerge in different types of graphene/boron nitride moiré superlattices, whereas correlated insulating states and superconductivity have been reported in twisted bilayer graphene moiré superlattices more...
- Published
- 2018
14. Direct Growth of Single- and Few-Layer MoS2 on h-BN with Preferred Relative Rotation Angles
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Michael F. Crommie, Aiming Yan, Alex Zettl, Kenji Watanabe, Feng Wang, Takashi Taniguchi, Jairo Velasco, and Salman Kahn
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Condensed Matter - Materials Science ,Materials science ,Graphene ,Mechanical Engineering ,Materials Science (cond-mat.mtrl-sci) ,FOS: Physical sciences ,Bioengineering ,Heterojunction ,Nanotechnology ,General Chemistry ,Substrate (electronics) ,Chemical vapor deposition ,Condensed Matter Physics ,Flexible electronics ,law.invention ,chemistry.chemical_compound ,chemistry ,law ,Monolayer ,General Materials Science ,Molybdenum disulfide ,Layer (electronics) - Abstract
Monolayer molybdenum disulphide (MoS2) is a promising two-dimensional direct-bandgap semiconductor with potential applications in atomically thin and flexible electronics. An attractive insulating substrate or mate for MoS2 (and related materials such as graphene) is hexagonal boron nitride (h-BN). Stacked heterostructures of MoS2 and h-BN have been produced by manual transfer methods, but a more efficient and scalable assembly method is needed. Here we demonstrate the direct growth of single- and few-layer MoS2 on h-BN by chemical vapor deposition (CVD) method, which is scalable with suitably structured substrates. The growth mechanisms for single-layer and few-layer samples are found to be distinct, and for single-layer samples low relative rotation angles (, 22 pages, 5 figures more...
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- 2015
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15. High-performance transition metal–doped Pt 3 Ni octahedra for oxygen reduction reaction
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Zhaoyang Lin, Xiaoqing Huang, Aiming Yan, Xiangfeng Duan, Yu Chen, Mufan Li, Tim Mueller, Y. Morris Wang, Enbo Zhu, Liang Cao, Alex Zettl, Zipeng Zhao, and Yu Huang
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Multidisciplinary ,chemistry ,Transition metal ,Molybdenum ,Inorganic chemistry ,chemistry.chemical_element ,Vanadium ,Nanotechnology ,Manganese ,Rhenium ,Tungsten ,Cobalt ,Catalysis - Abstract
Molybdenum doping drives high activity Platinum (Pt) is an effective catalyst of the oxygen reduction reaction in fuel cells but is scarce. One approach to extend Pt availability is to alloy it with more abundant metals such as nickel (Ni). Although these catalysts can be highly active, they are often not durable because of Ni loss. Huang et al. show that doping the surface of octahedral Pt 3 Ni nanocrystals with molybdenum not only leads to high activity (∼80 times that of a commercial catalyst) but enhances their stability. Science , this issue p. 1230 more...
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- 2015
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16. Distinct lipid profile in haemolytic anaemia-related gallstones compared with the general gallstone
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Ziqi Wan, Xiaoyin Bai, Chengqing He, Yueyi Zhang, Ying Wang, Kaini Shen, Li Meizi, Qiang Wang, Wu Dongsheng, Yunlu Feng, and Aiming Yang
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Gallstones ,haemolytic anaemia ,hypocholesterolemia ,hypolipidaemia ,Medicine - Abstract
AbstractBackground Pigment gallstones are not uncommon among patients with chronic haemolytic anaemia. But their clinical characteristics have not been described in detail and not been directly compared with the general gallstone population.Methods Patients at Peking Union Medical College Hospital with haemolytic anaemia and subsequent gallstones from January 2012 to December 2022 were included. Cases were matched (1:2) based on age, sex and location of stones to randomly select non-anaemia patients with gallstones (controls).Results Screening 899 cases of gallstones, we finally included 76 cases and 152 controls. Total cholesterol (TC), high-density lipoprotein (HDL), and low-density lipoprotein (LDL) for cases were 3.02 ± 0.98 mmol/L, 0.89 ± 0.30 mmol/L and 1.58 ± 0.70 mmol/L, respectively, significantly lower than those in the control group (all p more...
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- 2023
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17. Dynamics of Symmetry-Breaking Stacking Boundaries in Bilayer MoS2
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Steven G. Louie, Aiming Yan, Colin Ophus, Alex Zettl, Chin Shen Ong, Jim Ciston, Diana Y. Qiu, and Christian Merino
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Technology ,Materials science ,Point reflection ,Stacking ,FOS: Physical sciences ,02 engineering and technology ,Crystal structure ,01 natural sciences ,Physical Chemistry ,Engineering ,Mesoscale and Nanoscale Physics (cond-mat.mes-hall) ,0103 physical sciences ,Scanning transmission electron microscopy ,Monolayer ,cond-mat.mes-hall ,Symmetry breaking ,Physical and Theoretical Chemistry ,010306 general physics ,Condensed Matter - Materials Science ,Condensed Matter - Mesoscale and Nanoscale Physics ,Bilayer ,Materials Science (cond-mat.mtrl-sci) ,021001 nanoscience & nanotechnology ,Symmetry (physics) ,cond-mat.mtrl-sci ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Crystallography ,General Energy ,Chemical physics ,Chemical Sciences ,0210 nano-technology - Abstract
Crystal symmetry of two-dimensional (2D) materials plays an important role in their electronic and optical properties. Engineering symmetry in 2D materials has recently emerged as a promising way to achieve novel properties and functions. The noncentrosymmetric structure of monolayer transition metal dichalcogenides (TMDCs), such as molybdenum disulfide (MoS2), has allowed for valley control via circularly polarized optical excitation. In bilayer TMDCs, inversion symmetry can be controlled by varying the stacking sequence, thus providing a pathway to engineer valley selectivity. Here, we report the in situ integration of AA' and AB stacked bilayer MoS2 with different inversion symmetries by creating atomically sharp stacking boundaries between the differently stacked domains, via thermal stimulation and electron irradiation, inside an atomic-resolution scanning transmission electron microscopy. The setup enables us to track the formation and atomic motion of the stacking boundaries in real time and with ultrahigh resolution which enables in-depth analysis on the atomic structure at the boundaries. In conjunction with density functional theory calculations, we establish the dynamics of the boundary nucleation and expansion and further identify metallic boundary states. Our approach provides a means to synthesize domain boundaries with intriguing transport properties and opens up a new avenue for controlling valleytronics in nanoscale domains via real-time patterning of domains with different symmetry properties., The Journal of Physical Chemistry C, 2017 more...
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- 2017
18. Graphene: Preventing Thin Film Dewetting via Graphene Capping (Adv. Mater. 36/2017)
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Mattew A. Kolaczkowski, Peigen Cao, Hsin-Zon Tsai, Alex Zettl, Ke Xu, Yihan Xiao, Han Sae Jung, Yi Liu, Andrew S. Aikawa, Peter Bai, Arash A. Omrani, Ting Xu, Michael F. Crommie, Ramin Khajeh, Youngkyou Kim, Kacey Meaker, Griffin Rodgers, and Aiming Yan more...
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Materials science ,Mechanics of Materials ,Graphene ,law ,Mechanical Engineering ,General Materials Science ,Nanotechnology ,Dewetting ,Thin film ,Metallic thin films ,Graphene oxide paper ,law.invention - Published
- 2017
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19. Optically Discriminating Carrier-Induced Quasiparticle Band Gap and Exciton Energy Renormalization in MonolayerMoS2
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Yufeng Liang, Salman Kahn, Sefaattin Tongay, Nicholas J. Borys, Aslihan Suslu, P. James Schuck, Aiming Yan, Edward S. Barnard, Alex Zettl, and Kaiyuan Yao
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Physics ,Condensed matter physics ,Band gap ,business.industry ,Exciton ,Binding energy ,General Physics and Astronomy ,02 engineering and technology ,Condensed Matter::Mesoscopic Systems and Quantum Hall Effect ,021001 nanoscience & nanotechnology ,01 natural sciences ,Fundamental interaction ,Renormalization ,Condensed Matter::Materials Science ,Semiconductor ,0103 physical sciences ,Monolayer ,Quasiparticle ,010306 general physics ,0210 nano-technology ,business - Abstract
Optoelectronic excitations in monolayer ${\mathrm{MoS}}_{2}$ manifest from a hierarchy of electrically tunable, Coulombic free-carrier and excitonic many-body phenomena. Investigating the fundamental interactions underpinning these phenomena---critical to both many-body physics exploration and device applications---presents challenges, however, due to a complex balance of competing optoelectronic effects and interdependent properties. Here, optical detection of bound- and free-carrier photoexcitations is used to directly quantify carrier-induced changes of the quasiparticle band gap and exciton binding energies. The results explicitly disentangle the competing effects and highlight longstanding theoretical predictions of large carrier-induced band gap and exciton renormalization in two-dimensional semiconductors. more...
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- 2017
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20. Synthesis of single layer MOS2 array for surface Raman enhancement spectroscopy
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Xining Zang, Jing Li, Buxuan Li, Aiming Yan, Yao Chu, Minsong Wei, Liwei Lin, and Kaiyuan Yao
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Materials science ,Photoluminescence ,Chalcogenide ,Nanotechnology ,02 engineering and technology ,Substrate (electronics) ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,Rhodamine 6G ,chemistry.chemical_compound ,symbols.namesake ,chemistry ,Monolayer ,symbols ,0210 nano-technology ,Raman spectroscopy ,Molybdenum disulfide ,Raman scattering - Abstract
We present direct synthesis of high quality single-layer MoS 2 array on substrates with pre-deposited sulfur seeds for the first time with strong Raman signals of diluted Rhodamine 6G (R6G) due to Surface-Enhanced Raman Scattering (SERS). This work has following unprecedented accomplishments: (1) the usages of sulfur terminated substrate for the synthesis of CVD MoS 2 array; (2) SERS using the monolayer MoS 2 array with partially bowtie structures. (3) First time demonstration of SERS and photoluminescence (PL) on MoS 2 covered with Al 2 O 3 , which address the possibility of the physical enhancement mechanism. As such, the newly developed processes can enable large scale growth of MoS 2 for applications in bio-chemical sensing, and bring great inspiration in the 2D chalcogenide SERS mechanism. more...
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- 2017
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21. Molecular Arrangement and Charge Transfer in C
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Claudia, Ojeda-Aristizabal, Elton J G, Santos, Seita, Onishi, Aiming, Yan, Haider I, Rasool, Salman, Kahn, Yinchuan, Lv, Drew W, Latzke, Jairo, Velasco, Michael F, Crommie, Matthew, Sorensen, Kenneth, Gotlieb, Chiu-Yun, Lin, Kenji, Watanabe, Takashi, Taniguchi, Alessandra, Lanzara, and Alex, Zettl more...
- Abstract
Charge transfer at the interface between dissimilar materials is at the heart of electronics and photovoltaics. Here we study the molecular orientation, electronic structure, and local charge transfer at the interface region of C more...
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- 2017
22. Molecular Arrangement and Charge Transfer in C60/Graphene Heterostructures
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Haider I. Rasool, Takashi Taniguchi, Jairo Velasco, Salman Kahn, Chiu-Yun Lin, Alex Zettl, Drew Latzke, Kenji Watanabe, Kenneth Gotlieb, Elton J. G. Santos, Seita Onishi, Yinchuan Lv, Aiming Yan, Michael F. Crommie, Alessandra Lanzara, Claudia Ojeda-Aristizabal, and Matthew Sorensen more...
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Materials science ,Fullerene ,Graphene ,General Engineering ,General Physics and Astronomy ,Nanotechnology ,Heterojunction ,02 engineering and technology ,Electronic structure ,Substrate (electronics) ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,law.invention ,symbols.namesake ,Chemical physics ,law ,symbols ,Journal Article ,General Materials Science ,Density functional theory ,van der Waals force ,0210 nano-technology ,Graphene nanoribbons - Abstract
Charge transfer at the interface between dissimilar materials is at the heart of electronics and photovoltaics. Here we study the molecular orientation, electronic structure, and local charge transfer at the interface region of C60 deposited on graphene, with and without supporting substrates such as hexagonal boron nitride. We employ ab initio density functional theory with van der Waals (vdW) interactions, and experimentally characterize interface devices using high-resolution transmission electron microscopy and electronic transport. Charge transfer between C60 and the graphene is found to be sensitive to the nature of the underlying supporting substrate and to the crystallinity and local orientation of the C60. Even at room temperature, C60 molecules interfaced to graphene are orientationally locked into position. High electron and hole mobilities are preserved in graphene with crystalline C60 overlayers, which has ramifications for organic high-mobility field-effect devices. more...
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- 2017
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23. Optically Discriminating Carrier-Induced Quasiparticle Band Gap and Exciton Energy Renormalization in Monolayer MoS_{2}
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Kaiyuan, Yao, Aiming, Yan, Salman, Kahn, Aslihan, Suslu, Yufeng, Liang, Edward S, Barnard, Sefaattin, Tongay, Alex, Zettl, Nicholas J, Borys, and P James, Schuck
- Abstract
Optoelectronic excitations in monolayer MoS_{2} manifest from a hierarchy of electrically tunable, Coulombic free-carrier and excitonic many-body phenomena. Investigating the fundamental interactions underpinning these phenomena-critical to both many-body physics exploration and device applications-presents challenges, however, due to a complex balance of competing optoelectronic effects and interdependent properties. Here, optical detection of bound- and free-carrier photoexcitations is used to directly quantify carrier-induced changes of the quasiparticle band gap and exciton binding energies. The results explicitly disentangle the competing effects and highlight longstanding theoretical predictions of large carrier-induced band gap and exciton renormalization in two-dimensional semiconductors. more...
- Published
- 2017
24. Plasma assisted formation of 3D highly porous nanostructured metal oxide network on microheater platform for Low power gas sensing
- Author
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Sally Turner, Moonsuk Jang, Roya Maboudian, Alex Zettl, Aiming Yan, Hu Long, Hongmei Xu, and Carlo Carraro
- Subjects
Microheater ,Materials science ,Fabrication ,Oxide ,Nanotechnology ,02 engineering and technology ,010402 general chemistry ,01 natural sciences ,Metal ,chemistry.chemical_compound ,Materials Chemistry ,Electrical and Electronic Engineering ,Instrumentation ,chemistry.chemical_classification ,Detection limit ,Aqueous solution ,Metals and Alloys ,Polymer ,Plasma ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,chemistry ,visual_art ,visual_art.visual_art_medium ,0210 nano-technology - Abstract
A facile and versatile approach that integrates highly porous metal oxide nanostructured network with a low power microheater platform is presented for the creation of low-power, miniaturized gas sensors. Highly porous nanostructured metal oxide network is formed by oxygen plasma treatment of a metal containing polymer film followed by a heat treatment. A generalized aqueous metal precursor solution allows a large variety of metal salts to be incorporated into cast polymer films, thus forming nanostructured metal oxide network with various compositions. Gas sensing behavior is demonstrated for Co3O4 -based devices, exhibiting high sensitivity, low detection limit, and fast response and recovery towards formaldehyde gas. The overall fabrication process is flexible and highly scalable. This facile and flexible fabrication method can be used to reproducibly fabricate a variety of low power gas sensors with tunable performances for many applications and has great potential for mass production. more...
- Published
- 2019
- Full Text
- View/download PDF
25. Metallo‐Hydrogel‐Assisted Synthesis and Direct Writing of Transition Metal Dichalcogenides
- Author
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J. Nathan Hohman, Minsong Wei, Junqiao Wu, P. James Schuck, Alex Zettl, Liwei Lin, Penghong Ci, Takeshi Hayasaka, Xining Zang, Aiming Yan, and Kaiyuan Yao
- Subjects
Biomaterials ,Materials science ,Transition metal ,Electrochemistry ,Nanotechnology ,Self-assembly ,Direct writing ,Condensed Matter Physics ,Contact print ,Electronic, Optical and Magnetic Materials - Published
- 2019
- Full Text
- View/download PDF
26. Author Correction: Observation of moiré excitons in WSe2/WS2 heterostructure superlattices
- Author
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Alex Zettl, Sijie Yang, Sefaattin Tongay, Kenji Watanabe, M. Iqbal Bakti Utama, Emma C. Regan, Shenyang Shi, Sihan Zhao, Aiming Yan, Zhiren Zheng, Takashi Taniguchi, Ying Qin, Feng Wang, Danqing Wang, and Chenhao Jin more...
- Subjects
Physics ,Multidisciplinary ,Superlattice ,Exciton ,Heterojunction ,02 engineering and technology ,Moiré pattern ,021001 nanoscience & nanotechnology ,01 natural sciences ,Engineering physics ,0103 physical sciences ,Scanning transmission electron microscopy ,010306 general physics ,0210 nano-technology - Abstract
Change history: In this Letter, the following text has been added to the Acknowledgements section: "the scanning transmission electron microscopy measurements at the Molecular Foundry were supported by the Office of Science, Office of Basic Energy Sciences, of the US Department of Energy under contract number DE-AC02-05CH11231". See accompanying Amendment. more...
- Published
- 2019
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27. Wafer-scale on-chip synthesis and field emission properties of vertically aligned boron nitride based nanofiber arrays
- Author
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Alex Zettl, Hiroya Ishida, Zhen Guo, Thang Pham, S. Matt Gilbert, Aiming Yan, Hu Long, Sally Turner, and Wu Shi
- Subjects
010302 applied physics ,Materials science ,Physics and Astronomy (miscellaneous) ,business.industry ,Carbon nanofiber ,Wide-bandgap semiconductor ,02 engineering and technology ,Glassy carbon ,021001 nanoscience & nanotechnology ,01 natural sciences ,Nanomaterials ,Field electron emission ,chemistry.chemical_compound ,chemistry ,Boron nitride ,Nanofiber ,0103 physical sciences ,Optoelectronics ,Wafer ,0210 nano-technology ,business - Abstract
One dimensional boron nitride (BN) nanomaterials with a high aspect ratio are of great interest due to their unique properties and potential applications. However, BN nanomaterials are generally difficult to synthesize. Here, we describe the creation of arrays of vertically aligned pure BN nanofibers and BN coated carbon nanofibers, fabricated on-chip via a straightforward template-assisted chemical conversion reaction. The template, a glassy carbon nanofiber array, is produced by plasma processing of conventional photoresists. The method is highly controllable, patternable, and scalable, and the final arrays can be fabricated over large areas with a controlled fiber length. We characterize the electron field emission properties of the BN-coated carbon nanofiber array and find a large field enhancement factor, low turn-on voltage, and good stability. The outstanding field emission performance results from the small tip size and high aspect ratio of the nanofiber as well as the high chemical stability and high thermal conductivity of the BN coating. more...
- Published
- 2019
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28. Gastroblastoma Treated by Endoscopic Submucosal Excavation with a Novel PTCH1::GLI2 Fusion: A Rare Case Report and Literature Review
- Author
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Yongru Liu, Huanwen Wu, Xi Wu, Yunlu Feng, Qingwei Jiang, Qiang Wang, and Aiming Yang
- Subjects
gastroblastoma ,stomach tumor ,PTCH1::GLI2 fusion ,MALAT1-GLI1 fusion ,endoscopic submucosal excavation ,endoscopic treatment ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Gastroblastoma is an extremely rare stomach tumor that primarily presents in adolescent and early adulthood, with a biphasic cell morphology of epithelioid and spindle cells. In light of its similarity to other childhood blastomas, it has been named gastroblastoma. Few patients showed a potential of metastasis and recurrence, however, most of the reported cases were alive, with no evidence of the disease after surgical treatment. Commonly, MALAT1-GLI1 fusion has been considered to be the most relevant mutation. Herein, we present a case of an asymptomatic 58-year-old man who happened to find a submucosal gastric mass during a gastroscope and received endoscopic submucosal excavation (ESE). He turned out to have a gastroblastoma with a novel PTCH1::GLI2 fusion confirmed by Sanger sequencing. The patient was discharged two days after ESE without any complication and was recurrence-free during his one-year follow-up. According to the previous literature and our own experience, in cases with characteristic histopathology and immunohistochemistry patterns, a diagnosis of gastroblastoma should be considered even without a MALAT1-GLI1 fusion. Gastroblastoma pursues a favorable clinical outcome and endoscopic therapy could be an effective alternative treatment choice. more...
- Published
- 2022
- Full Text
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29. Oxygen 'Getter' Effects on Microstructure and Carrier Transport in Low Temperature Combustion-Processed a-InXZnO (X = Ga, Sc, Y, La) Transistors
- Author
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Jonathan W. Hennek, Tobin J. Marks, Vinayak P. Dravid, Myung-Gil Kim, Wei Zhao, Antonio Facchetti, Jeremy Smith, and Aiming Yan
- Subjects
Ionic radius ,Chemistry ,Analytical chemistry ,General Chemistry ,Biochemistry ,Dark field microscopy ,Catalysis ,Colloid and Surface Chemistry ,X-ray photoelectron spectroscopy ,Thin-film transistor ,Getter ,Scanning transmission electron microscopy ,Thermal analysis ,Oxygen binding - Abstract
In oxide semiconductors, such as those based on indium zinc oxide (IXZO), a strong oxygen binding metal ion ("oxygen getter"), X, functions to control O vacancies and enhance lattice formation, hence tune carrier concentration and transport properties. Here we systematically study, in the IXZO series, the role of X = Ga(3+) versus the progression X = Sc(3+) → Y(3+) → La(3+), having similar chemical characteristics but increasing ionic radii. IXZO films are prepared from solution over broad composition ranges for the first time via low-temperature combustion synthesis. The films are characterized via thermal analysis of the precursor solutions, grazing incidence angle X-ray diffraction (GIAXRD), atomic force microscopy (AFM), X-ray photoelectron spectroscopy (XPS), and scanning transmission electron microscopy (STEM) with high angle annular dark field (HAADF) imaging. Excellent thin-film transistor (TFT) performance is achieved for all X, with optimal compositions after 300 °C processing exhibiting electron mobilities of 5.4, 2.6, 2.4, and 1.8 cm(2) V(-1) s(-1) for Ga(3+), Sc(3+), Y(3+), and La(3+), respectively, and with I(on)/I(off) = 10(7)-10(8). Analysis of the IXZO TFT positive bias stress response shows X = Ga(3+) to be superior with mobilities (μ) retaining95% of the prestress values and threshold voltage shifts (ΔV(T)) of1.6 V, versus85% μ retention and ΔV(T) ≈ 20 V for the other trivalent ions. Detailed microstructural analysis indicates that Ga(3+) most effectively promotes oxide lattice formation. We conclude that the metal oxide lattice formation enthalpy (ΔH(L)) and metal ionic radius are the best predictors of IXZO oxygen getter efficacy. more...
- Published
- 2013
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30. Sensing Behavior of Atomically Thin-Layered MoS2 Transistors
- Author
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Sharmila N. Shirodkar, Yi Kai Huang, Jiajun Luo, Vinayak P. Dravid, Jagaran Acharya, Daniel Charles, C. N. R. Rao, Dattatray J. Late, Umesh V. Waghmare, Aiming Yan, and B. T. Liu
- Subjects
Materials science ,business.industry ,Transistor ,General Engineering ,Ab initio ,General Physics and Astronomy ,Light irradiation ,Nanotechnology ,Green-light ,Exfoliation joint ,law.invention ,symbols.namesake ,Optical microscope ,law ,symbols ,Optoelectronics ,General Materials Science ,Density functional theory ,business ,Raman spectroscopy - Abstract
Most of recent research on layered chalcogenides is understandably focused on single atomic layers. However, it is unclear if single-layer units are the most ideal structures for enhanced gas-solid interactions. To probe this issue further, we have prepared large-area MoS2 sheets ranging from single to multiple layers on 300 nm SiO2/Si substrates using the micromechanical exfoliation method. The thickness and layering of the sheets were identified by optical microscope, invoking recently reported specific optical color contrast, and further confirmed by AFM and Raman spectroscopy. The MoS2 transistors with different thicknesses were assessed for gas-sensing performances with exposure to NO2, NH3, and humidity in different conditions such as gate bias and light irradiation. The results show that, compared to the single-layer counterpart, transistors of few MoS2 layers exhibit excellent sensitivity, recovery, and ability to be manipulated by gate bias and green light. Further, our ab initio DFT calculations on single-layer and bilayer MoS2 show that the charge transfer is the reason for the decrease in resistance in the presence of applied field. more...
- Published
- 2013
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- View/download PDF
31. Electron Tomography of Au-Catalyzed Semiconductor Nanowires
- Author
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Eric R. Hemesath, Lincoln J. Lauhon, Eiko Nakazawa, Vinayak P. Dravid, Justin G. Connell, Aiming Yan, Jinsong Wu, Sujing Xie, Xiaofeng Zhang, George Liu, Sonal Padalkar, and Jipeng Cheng
- Subjects
Materials science ,business.industry ,Nanowire ,Nanoparticle ,Nanotechnology ,Focused ion beam ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Nanomaterials ,Characterization (materials science) ,General Energy ,Semiconductor ,Electron tomography ,Scanning transmission electron microscopy ,Physical and Theoretical Chemistry ,business - Abstract
Electron tomography based on Z-contrast scanning transmission electron microscopy (STEM) can be applied to study 3D morphology of nanomaterials at high resolution, that is, 1 nm in all three spatial dimensions, to provide comprehensive insights into the structure of nanomaterials and their interfaces. Here, we report the 3D characterization of Au-catalyzed Ge and Si nanowires using a full-space tilting holder to address the “missing wedge” problem in STEM electron tomography. Electron tomography specimens were prepared by a novel two-step sample preparation process to minimize surface damage induced by focused ion beam (FIB) milling. The quality of specimen preparation protocol is demonstrated by the clear visibility of {112} facets in the reconstructed volume, and 3D morphology of Au nanoparticles on the nanowire surface. The 3D distribution of the Au nanoparticles on the coated Ge nanowires is also established. The integrated combination of innovative specimen preparation and full-tilt tomography repres... more...
- Published
- 2013
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- View/download PDF
32. Electrostatically Driven Nanoballoon Actuator
- Author
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Alex Zettl, Steven G. Louie, Sinisa Coh, Eduardo Gracia-Espino, Gabriel Dunn, Thomas Wågberg, Marvin L. Cohen, Hamid Reza Barzegar, and Aiming Yan
- Subjects
Nanotube ,Materials science ,Bioengineering ,Nanotechnology ,02 engineering and technology ,Carbon nanotube ,01 natural sciences ,law.invention ,Computer Science::Robotics ,Condensed Matter::Materials Science ,law ,0103 physical sciences ,General Materials Science ,Tube (fluid conveyance) ,Manipulator ,010306 general physics ,business.industry ,Mechanical Engineering ,General Chemistry ,Condensed Matter::Mesoscopic Systems and Quantum Hall Effect ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Computer Science::Other ,In situ transmission electron microscopy ,Inflatable ,Optoelectronics ,0210 nano-technology ,business ,Actuator ,Voltage - Abstract
We demonstrate an inflatable nanoballoon actuator based on geometrical transitions between the inflated (cylindrical) and collapsed (flattened) forms of a carbon nanotube. In situ transmission electron microscopy experiments employing a nanoelectromechanical manipulator show that a collapsed carbon nanotube can be reinflated by electrically charging the nanotube, thus realizing an electrostatically driven nanoballoon actuator. We find that the tube actuator can be reliably cycled with only modest control voltages (few volts) with no apparent wear or fatigue. A complementary theoretical analysis identifies critical parameters for nanotube nanoballoon actuation. more...
- Published
- 2016
33. Identifying and Engineering the Stacking Sequence in CVD Grown Few-layer MoS2 via Aberration-corrected STEM
- Author
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Christian Merino, Jim Ciston, Alex Zettl, Aiming Yan, Colin Ophus, and Wei Chen
- Subjects
Materials science ,0103 physical sciences ,Stacking ,Nanotechnology ,02 engineering and technology ,021001 nanoscience & nanotechnology ,010306 general physics ,0210 nano-technology ,01 natural sciences ,Instrumentation ,Layer (electronics) ,Sequence (medicine) - Published
- 2017
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34. Refractory ascites after laparoscopic cholecystectomy: a case report
- Author
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Xiaoyun Cheng, Jin Huang, Aiming Yang, and Qiang Wang
- Subjects
Refractory ascites ,Chylous leakage ,Laparoscopic cholecystectomy ,Lymphatic vessels ,Lymphoscintigraphy ,Case report ,Surgery ,RD1-811 - Abstract
Abstract Background Laparoscopic cholecystectomy is a common surgical option for gallstone disease with minimal trauma and rapid recovery. Ascites is a relatively uncommon complication after laparoscopic cholecystectomy and is more frequently observed in patients with preoperative abnormal liver function. However, patients without underlying liver disease develop refractory ascites after laparoscopic cholecystectomy are rare. We report a case of massive ascites caused by lymphatic injury after laparoscopic cholecystectomy. Case presentation A 63-year-old woman complained of abdominal discomfort and distension at the twelfth day after a laparoscopic cholecystectomy for gallbladder stones. Subsequently, the patient developed spontaneous bacterial peritonitis and a decreased output of urine. Abdominal computed tomography (CT) identified abdominal effusion. The patient received abdominocentesis and the volume of slightly turbid yellow ascites averaged 1500–2000 ml per day. The results of laboratory analysis of ascitic fluid showed the following: serum-ascites albumin-gradient (SAAG), 11–12 g/L; albumin, 11–14 g/L; triglycerides, 0.91 mmol/L. After the diuretic therapy, repeated large-volume paracentesis with albumin supplementation, administration of antibiotics and renal vasodilating medications, the patient’s symptoms did not relieve. Lymphoscintigraphy found a small amount of radioactive filling in the abdominal cavity. The patient finally received surgery with detection and ligation of the lymphatic leak. The ascites disappeared and the patient recovered well. Conclusions For patients with atypical characteristics of chylous ascites, lymphoscintigraphy could help to localize and qualify the diagnosis. Surgical treatment could be considered when conservative treatment fails. more...
- Published
- 2022
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35. Identifying different stacking sequences in few-layer CVD-grownMoS2by low-energy atomic-resolution scanning transmission electron microscopy
- Author
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Alex Zettl, Yuyuan Lin, Aiming Yan, Colin Ophus, Jim Ciston, Kristin A. Persson, and Wei Chen
- Subjects
Physics ,Stacking ,Nanotechnology ,02 engineering and technology ,Chemical vapor deposition ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Computer Science::Digital Libraries ,01 natural sciences ,0104 chemical sciences ,Crystallography ,Low energy ,Atomic resolution ,Scanning transmission electron microscopy ,Density functional theory ,0210 nano-technology ,Layer (electronics) - Abstract
Atomically thin $\mathrm{Mo}{\mathrm{S}}_{2}$ grown by chemical vapor deposition (CVD) is a promising candidate for next-generation electronics due to inherent CVD scalability and controllability. However, it is well known that the stacking sequence in few-layer $\mathrm{Mo}{\mathrm{S}}_{2}$ can significantly impact electrical and optical properties. Herein we report different intrinsic stacking sequences in CVD-grown few-layer $\mathrm{Mo}{\mathrm{S}}_{2}$ obtained by atomic-resolution annular-dark-field imaging in an aberration-corrected scanning transmission electron microscope operated at 50 keV. Trilayer $\mathrm{Mo}{\mathrm{S}}_{2}$ displays a new stacking sequence distinct from the commonly observed $2H$ and $3R$ phases of $\mathrm{Mo}{\mathrm{S}}_{2}$. Density functional theory is used to examine the stability of different stacking sequences, and the findings are consistent with our experimental observations. more...
- Published
- 2016
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- View/download PDF
36. Interactions between vaginal local cytokine IL-2 and high-risk human papillomavirus infection with cervical intraepithelial neoplasia in a Chinese population-based study
- Author
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Ruoxi Zhu, Wenhao Wang, Aiming Yang, Weihong Zhao, Wei Wang, Zhilian Wang, Jintao Wang, Yongli Hou, Xiaoqiang Su, Lili Zhang, Bo Feng, Jing Yang, Zhe Wang, Xiaofen Niu, Weiguo Lv, Zhican Qu, and Min Hao more...
- Subjects
cervical intraepithelial neoplasia ,cytokines ,IL-2 ,high-risk human papillomavirus infection ,cervical cancer ,Microbiology ,QR1-502 - Abstract
BackgroundAlthough interleukin-2 (IL-2) has long been associated with cancer development, its roles in the development of cervical cancer remains unclear. Few studies examined the associations between IL-2 and high-risk human papillomavirus (HPV) with risk of cervical intraepithelial neoplasia (CIN).ObjectiveWe aimed to assess the association of IL-2 and high-risk HPV infection with risk of CIN as well as their interactions on the risk of CIN.DesignWe performed a cross-sectional analysis of screening data in 2285 women aged 19-65 years who participated in an ongoing community-based cohort of 40,000 women in Shanxi, China in 2014-2015. Both categorical and spline analyses were used to evaluation the association between IL-2 in the local vaginal fluids and prevalence of CIN. In addition, 1503 controls were followed up until January 31, 2019), the nested case-control study design was adopted to evaluate the association of vaginal lavage IL-2 levels and the risk of CIN progression.ResultsAfter adjusting for potential confounders, IL-2 levels were statistically inversely associated with prevalence of CIN (the 1st versus 4th quartile IL-2 levels: the respective odds ratio [OR] and 95% confidence intervals [CI] was: = 1.75 [1.37, 2.23] for CIN, 1.32 [1.01, 1.73] for CIN I, and 3.53 [2.26, 5.52] for CIN II/III). Increased IL-2 levels were inversely associated with prevalence of CIN (P-overall more...
- Published
- 2023
- Full Text
- View/download PDF
37. Endoscopic mucosal resection using cold snare versus hot snare in treatment for 10–19 mm non-pedunculated colorectal polyps: protocol of a non-inferiority randomised controlled study
- Author
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Yuelun Zhang, Aiming Yang, Dong Wu, Duan Wang, Shengyu Zhang, Xiaxiao Yan, Qingwei Jiang, and Yunlu Feng
- Subjects
Medicine - Abstract
Introduction Cold polypectomy has the advantages of simple operation, less time-consuming and fewer complications. Guidelines have recommended cold snare polypectomy (CSP) to resect small polyps sized ≤5 mm and sessile polyps sized 6–9 mm. However, evidence is scarce regarding cold resection for non-pedunculated polyps sized ≥10 mm. Cold snare endoscopic mucosal resection (CS-EMR) combining CSP and submucosal injection was designed to improve the complete resection rate and reduce adverse events. We hypothesise that CS-EMR is non-inferior to conventional hot snare endoscopic mucosal resection (HS-EMR) in the resection of 10–19 mm non-pedunculated colorectal polyps.Methods and analysis This study is a prospective, randomised, open-label, non-inferiority, single-centre trial. Outpatients scheduled to undergo a colonoscopy and present eligible polyps will be randomised to receive either CS-EMR or HS-EMR. The primary endpoint is the complete resection. Considering that HS-EMR of 10–19 mm colorectal polyps will yield a complete resection rate of at least 92% and a non-inferiority margin of −10%, a total of 232 polyps will be included (one-sided α, 2.5%; β, 20%). The analyses are intended to evaluate first non-inferiority (lower limit 95% CI greater than −10% for group difference) and then superiority (lower limit 95% CI>0%) if non-inferiority is achieved. Secondary endpoints include en-bloc resection, the occurrence of adverse events, the use of endoscopic clips, resection time and cost.Ethics and dissemination The study has been approved by the institutional review board of the Peking Union Medical College Hospital (No. K2203). All participants in the trial will provide written informed consent. The results of this trial will be published in an open-access way.Trial registration number NCT05545787. more...
- Published
- 2023
- Full Text
- View/download PDF
38. Fabrication of One-Dimensional Zigzag [6,6]-Phenyl-C61-Butyric Acid Methyl Ester Nanoribbons from Two-Dimensional Nanosheets
- Author
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Alex Zettl, Aiming Yan, Hamid Reza Barzegar, Thomas Wågberg, Tiva Sharifi, and Eduardo Gracia-Espino
- Subjects
Nanoteknik ,nanosheets ,Materials science ,Nanostructure ,Organic solar cell ,electron croscopy ,General Physics and Astronomy ,Nanotechnology ,Crystal structure ,Physical Chemistry ,chemistry.chemical_compound ,Molecule ,General Materials Science ,nanoribbons ,Fysikalisk kemi ,liquid-liquid interfacial precipitation ,General Engineering ,Acceptor ,Phenyl-C61-butyric acid methyl ester ,PCBM ,Crystallography ,Zigzag ,chemistry ,Nano Technology ,Nanorod ,density functional theory calculations ,nanorods - Abstract
One-dimensional (10) zigzag [6,6]-phenyl-C61-butyric acid methyl ester (PCBM) nanoribbons are produced by folding two-dimensional ultrathin PCBM nanosheets in a simple solvent process. The unique 1D PCBM nanostructures exhibit uniform width of 3.8 +/- 0.3 nm, equivalent to four PCBM molecules, and lengths of 20-400 nm. These nanoribbons show well-defined crystalline structure, comprising PCBM molecules in a hexagonal arrangement without trapped solvent molecules. First-principle calculations and detailed experimental characterization provide an insight into the structure and formation mechanism of the 1D PCBM nanoribbons. Given their dimensions and physical properties, we foresee that these nanostructures should be ideal as acceptor material in organic solar cells. more...
- Published
- 2015
39. Self-Passivation of Defects: Effects of High-Energy Particle Irradiation on the Elastic Modulus of Multilayer Graphene
- Author
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Deyi Fu, Alex Zettl, Kin Man Yu, Joonki Suh, Daryl C. Chrzan, Cheng Lun Hsin, Junqiao Wu, Yinghui Sun, Sefaattin Tongay, Joonsuk Park, Haimei Zheng, Michelle Chen, Wenli Guo, Kai Liu, and Aiming Yan
- Subjects
Materials science ,High energy particle ,Passivation ,Graphene ,Mechanical Engineering ,Stiffness ,Nanotechnology ,law.invention ,Mechanics of Materials ,law ,medicine ,General Materials Science ,Irradiation ,medicine.symptom ,Composite material ,Elastic modulus ,Graphene nanoribbons ,Graphene oxide paper - Abstract
The elastic modulus of multilayer graphene is found to be more robust to damage created by high-energy α-particle irradiation as compared to monolayer graphene. Theoretical analysis indicates that irradiation of multilayer graphene generates interlayer links that potentially increase the stiffness of the multilayer by passivating local defects. more...
- Published
- 2015
40. Correction: Endoscopic and histopathological hints on infections in patients of common variable immunodeficiency disorder with gastrointestinal symptoms
- Author
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Yang Chen, Yan You, Ji Li, Aiming Yang, Weixun Zhou, and Xiaoqing Li
- Subjects
Diseases of the digestive system. Gastroenterology ,RC799-869 - Published
- 2024
- Full Text
- View/download PDF
41. C₆₀/collapsed carbon nanotube hybrids: a variant of peapods
- Author
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Hamid Reza, Barzegar, Eduardo, Gracia-Espino, Aiming, Yan, Claudia, Ojeda-Aristizabal, Gabriel, Dunn, Thomas, Wågberg, and Alex, Zettl
- Abstract
We examine a variant of so-called carbon nanotube peapods by packing C60 molecules inside the open edge ducts of collapsed carbon nanotubes. C60 insertion is accomplished through a facile single-step solution-based process. Theoretical modeling is used to evaluate favorable low-energy structural configurations. Overfilling of the collapsed tubes allows infiltration of C60 over the full cross-section of the tubes and consequent partial or complete reinflation, yielding few-wall, large diameter cylindrical nanotubes packed with crystalline C60 solid cores. more...
- Published
- 2015
42. C60/Collapsed Carbon Nanotube Hybrids : A Variant of Peapods
- Author
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Alex Zettl, Gabriel Dunn, Claudia Ojeda-Aristizabal, Aiming Yan, Hamid Reza Barzegar, Thomas Wågberg, and Eduardo Gracia-Espino
- Subjects
Fullerene ,Materials science ,Mechanical Engineering ,Bioengineering ,silocrystals ,General Chemistry ,Carbon nanotube ,Condensed Matter Physics ,law.invention ,Condensed Matter::Materials Science ,law ,fullerenes ,Physics::Atomic and Molecular Clusters ,Molecule ,Peapods ,General Materials Science ,Composite material ,collapsed carbon nanotubes ,Large diameter ,Den kondenserade materiens fysik - Abstract
We examine a variant of so-called carbon nanotube peapods by packing C60 molecules inside the open edge ducts of collapsed carbon nanotubes. C60 insertion is accomplished through a facile single-step solution-based process. Theoretical modeling is used to evaluate favorable low-energy structural configurations. Overfilling of the collapsed tubes allows infiltration of C60 over the full cross-section of the tubes and consequent partial or complete reinflation, yielding few-wall, large diameter cylindrical nanotubes packed with crystalline C60 solid cores. more...
- Published
- 2015
43. Preventing Thin Film Dewetting via Graphene Capping
- Author
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Aiming Yan, Arash A. Omrani, Peigen Cao, Michael F. Crommie, Andrew S. Aikawa, Ke Xu, Hsin-Zon Tsai, Ramin Khajeh, Han Sae Jung, Yihan Xiao, Youngkyou Kim, Yi Liu, Mattew A. Kolaczkowski, Ting Xu, Alex Zettl, Kacey Meaker, Griffin Rodgers, and Peter Bai more...
- Subjects
Materials science ,Spinodal decomposition ,Nanotechnology ,02 engineering and technology ,010402 general chemistry ,01 natural sciences ,law.invention ,chemistry.chemical_compound ,law ,Monolayer ,General Materials Science ,Dewetting ,Thin film ,chemistry.chemical_classification ,Graphene ,business.industry ,Mechanical Engineering ,Polymer ,021001 nanoscience & nanotechnology ,0104 chemical sciences ,Organic semiconductor ,chemistry ,Mechanics of Materials ,Optoelectronics ,Polystyrene ,0210 nano-technology ,business - Abstract
A monolayer 2D capping layer with high Young's modulus is shown to be able to effectively suppress the dewetting of underlying thin films of small organic semiconductor molecule, polymer, and polycrystalline metal, respectively. To verify the universality of this capping layer approach, the dewetting experiments are performed for single-layer graphene transferred onto polystyrene (PS), semiconducting thienoazacoronene (EH-TAC), gold, and also MoS2 on PS. Thermodynamic modeling indicates that the exceptionally high Young's modulus and surface conformity of 2D capping layers such as graphene and MoS2 substantially suppress surface fluctuations and thus dewetting. As long as the uncovered area is smaller than the fluctuation wavelength of the thin film in a dewetting process via spinodal decomposition, the dewetting should be suppressed. The 2D monolayer-capping approach opens up exciting new possibilities to enhance the thermal stability and expands the processing parameters for thin film materials without significantly altering their physical properties. more...
- Published
- 2017
- Full Text
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44. Mitochondria in innate immunity signaling and its therapeutic implications in autoimmune diseases
- Author
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Yuhao Jiao, Zhiyu Yan, and Aiming Yang
- Subjects
mitochondria ,innate immunity ,immune metabolism ,autoimmune disease ,therapeutic targets ,Immunologic diseases. Allergy ,RC581-607 - Abstract
Autoimmune diseases are characterized by vast alterations in immune responses, but the pathogenesis remains sophisticated and yet to be fully elucidated. Multiple mechanisms regulating cell differentiation, maturation, and death are critical, among which mitochondria-related cellular organelle functions have recently gained accumulating attention. Mitochondria, as a highly preserved organelle in eukaryotes, have crucial roles in the cellular response to both exogenous and endogenous stress beyond their fundamental functions in chemical energy conversion. In this review, we aim to summarize recent findings on the function of mitochondria in the innate immune response and its aberrancy in autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, etc., mainly focusing on its direct impact on cellular metabolism and its machinery on regulating immune response signaling pathways. More importantly, we summarize the status quo of potential therapeutic targets found in the mitochondrial regulation in the setting of autoimmune diseases and wish to shed light on future studies. more...
- Published
- 2023
- Full Text
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45. Impact of Helicobacter pylori on the gastric microbiome in patients with chronic gastritis: a systematic review and meta-analysis protocol
- Author
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Aiming Yang, Xinyu Zhao, Ruoyu Ji, Xinyuan Cao, Yizhen Zhang, Yingyun Yang, and Weiyang Zheng
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Medicine - Abstract
Introduction Chronic gastritis is a common disease worldwide. Studies have consistently shown that chronic gastritis is usually associated with gastric microbial dysbiosis, especially the infection of Helicobacter pylori. However, the interaction between H. pylori and non-H. pylori bacteria in patients with chronic gastritis has not been clearly identified yet. Consequently, we designed a protocol for a systematic review and meta-analysis, which focused on identifying the changes in gastrointestinal microbiota composition between patients with H. pylori-infective and non-infective chronic gastritis.Method and analysis We will search PubMed, EMBASE and Cochrane Library databases to retrieve observational studies on humans. The eligible studies must include data about the relative abundance of the gastrointestinal microbiome in patients with H. pylori-infective or non-infective chronic gastritis. Only the data of adults aged over 18 years will be analysed. Two researchers will extract the data independently, and Newcastle–Ottawa Scale will be used to assess the risk of bias. Random-effects model will be performed in quantitative analyses. Correlation analysis, bioinformatics analysis and function analysis will be performed.Discussion Currently, numerous studies have revealed the role of H. pylori in chronic gastritis. However, the alterations of non-H. pylori bacteria in patients with chronic gastritis remain an open question. The results of our study might provide new insights into future diagnosis and treatments.Ethics and dissemination This study is based on published documents, unrelated to personal data, so ethical approval is not in need. The results of this study are expected to be published in journals or conference proceedings.PROSPERO registration number CRD42020205260; Pre-results. more...
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- 2023
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46. Protocol of a randomised controlled trial to assess medical staff’s inhalation exposure to infectious particles exhaled by patients during oesophagogastroduodenoscopy and the efficacy of surgical masks in this context
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Li Liu, Aiming Yang, Xi Wu, Shengyu Zhang, Zhiyu Yan, Yuheng Zhang, and Mengjie Duan
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Medicine - Abstract
Background Aerosol-generating procedures such as oesophagogastroduodenoscopy (OGD) result in infectious particles being exhaled by patients. This substantially increases the medical staff’s risk of occupational exposure to pathogenic particles via airway inhalation and facial mucosal deposition. Infectious particles are regarded as a key route of transmission of SARS-CoV-2 and, thus, represents a major risk factor for medical staff during the ongoing COVID-19 pandemic. There is a need for quantitative evidence on medical staff’s risk of multiroute exposure to infectious particles exhaled by patients during OGD to enable the development of practical, feasible and economical methods of risk-reduction for use in OGD and related procedures. This randomised controlled trial (RCT)—Personal protective EquiPment intervention TrIal for oesophagogastroDuodEnoscopy (PEPTIDE)—aims to establish a state-of-the-art protocol for quantifying the multiroute exposure of medical staff to infectious particles exhaled by patients during real OGD procedures.Method and analysis PEPTIDE will be a prospective, two-arm, RCT using quantitative methods and will be conducted at a tertiary hospital in China. It will enrol 130 participants (65 per group) aged over 18. The intervention will be an anthropomorphic model with realistic respiratory-related morphology and respiratory function that simulates a medical staff member. This model will be used either without or with a surgical mask, depending on the group allocation of a participant, and will be placed beside the participants as they undergo an OGD procedure. The primary outcome will be the anthropomorphic model’s airway dosage of the participants’ exhaled infectious particles with or without a surgical mask, and the secondary outcome will be the anthropomorphic model’s non-surgical mask-covered facial mucosa dosage of the participants’ exhaled infectious particles. Analyses will be performed in accordance with the type of data collected (categorical or quantitative data) using SPSS (V.26.0) and RStudio (V.1.3.959).Ethics and dissemination Ethical approval for this RCT was obtained from the Ethics Committee of Peking Union Medical College Hospital (ZS-3377). All of the potential participants who agree to participate will provide their written informed consent before they are enrolled. The results will be disseminated through presentations at national and international conferences and publications in peer-reviewed journals.Trial registration number NCT05321056. more...
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- 2023
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47. Synthesis and characterization of highly crystalline graphene aerogels
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Thang Pham, Marcus A. Worsley, S. J. Shin, Aiming Yan, Michael Bagge-Hansen, William Mickelson, Alex Zettl, and Jonathan R. I. Lee
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Materials science ,Graphene ,General Engineering ,General Physics and Astronomy ,Aerogel ,Nanotechnology ,Porosimetry ,law.invention ,symbols.namesake ,Crystallinity ,law ,symbols ,General Materials Science ,Graphite ,Crystallization ,Raman spectroscopy ,Graphene oxide paper - Abstract
Aerogels are used in a broad range of scientific and industrial applications due to their large surface areas, ultrafine pore sizes, and extremely low densities. Recently, a large number of reports have described graphene aerogels based on the reduction of graphene oxide (GO). Though these GO-based aerogels represent a considerable advance relative to traditional carbon aerogels, they remain significantly inferior to individual graphene sheets due to their poor crystallinity. Here, we report a straightforward method to synthesize highly crystalline GO-based graphene aerogels via high-temperature processing common in commercial graphite production. The crystallization of the graphene aerogels versus annealing temperature is characterized using Raman and X-ray absorption spectroscopy, X-ray diffraction, and electron microscopy. Nitrogen porosimetry shows that the highly crystalline graphene macrostructure maintains a high surface area and ultrafine pore size. Because of their enhanced crystallinity, these graphene aerogels exhibit a ∼ 200 °C improvement in oxidation temperature and an order of magnitude increase in electrical conductivity. more...
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- 2014
48. Endoscopic characteristics in predicting prognosis of biopsy-diagnosed gastric low-grade intraepithelial neoplasia
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Long Zou, Qingwei Jiang, Tao Guo, Xi Wu, Qiang Wang, Yunlu Feng, Shengyu Zhang, Weigang Fang, Weixun Zhou, Aiming Yang, and Yuanyuan Ji
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Medicine - Abstract
Abstract. Background:. Endoscopic biopsy can underestimate gastric malignancies as low-grade intraepithelial neoplasia (LGIN). Definitively diagnosed LGIN would progress. This study aimed to evaluate predictive factors to identify malignancies misdiagnosed as LGIN by biopsy and LGIN at high risk of progression. Methods:. The clinical records of patients diagnosed with gastric LGIN by endoscopic biopsy who underwent at least two endoscopies during the first year of follow-up between 2007 and 2017 were retrospectively collected. Three endoscopists reviewed photographs of the initial endoscopy, described lesion characteristics, and made endoscopic diagnoses. Logistic regression was used to analyze predictors to identify malignancies underestimated as LGIN. A receiver operating characteristic curve was used to evaluate the diagnostic accuracy of these predictors. Patient clinical outcomes of follow-up >1 year were collected. Kaplan–Meier estimates with log-rank tests and Cox proportional hazards regression were used to analyze predictors of progression. Results:. Overall, 48 of 182 (26.4%) patients were proven to have malignancies. A single lesion, a large lesion size, and marked intestinal metaplasia (IM) were independent predictors of initially misdiagnosed malignancies. The area under the curve of these predictors was 0.871, with a sensitivity of 68.7% and specificity of 92.5%. Twelve of 98 patients (12.2%) progressed during the 33-month median follow-up period. A whitish appearance, irregular margins, marked IM, and histological diagnosis of LGIN more than twice within the first year were predictors for progression. Conclusions:. Lesions diagnosed as LGIN by biopsy with marked IM and other predictors above should be prudently treated for high potential to be malignancies or progress. Endoscopic follow-up with repeated biopsies within the first year is recommended. more...
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- 2022
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49. Dietary patterns and severity of symptom with the risk of esophageal squamous cell carcinoma and its histological precursor lesions in China: a multicenter cross-sectional latent class analysis
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Zhaoping Zang, Yong Liu, Jialin Wang, Yuqin Liu, Shaokai Zhang, Yongzhen Zhang, Liwei Zhang, Deli Zhao, Fugang Liu, Lina Chao, Xinzheng Wang, Chunli Zhang, Guohui Song, Zhiyi Zhang, Youpeng Li, Zheng Yan, Yongxiu Wen, Yinyin Ge, Chen Niu, Wei Feng, Rena Nakyeyune, Yi Shen, Yi Shao, Xiuhua Guo, Aiming Yang, Fen Liu, and Guiqi Wang more...
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Esophageal squamous cell carcinoma ,Precancerous lesions ,Latent class analysis ,Dietary patterns ,Symptom ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Dietary patterns and symptoms research among Chinese with esophageal squamous cell carcinoma (ESCC) and its precursor lesions is limited, especially as it relates to multiple food consumption and multiple co-occurring symptoms. The aim of our study was to identify the dietary patterns and severity of symptom classes with the risk of esophageal squamous cell carcinoma and its histological precursor lesions, and develop a risk prediction model for different stages of esophageal disease. Methods We analyzed data from a multicenter cross-sectional study carried out in ESCC high incidence areas between 2017 and 2018, which included 34,707 individuals aged 40–69 years. Dietary patterns and severity of symptom classes were derived by applying a latent class analysis (LCA). A multiple logistic regression model was used to derive the odds ratio (ORs) and corresponding 95% confidence intervals (CIs) for ESCC and the different stages of esophageal disease according to the dietary patterns and severity of symptom classes identified. We built the risk prediction model by using a nomogram. Results We identified five dietary patterns and three severity of symptom classes. The dietary patterns were classified as follows: “Healthy”, “Western”, “Lower consumers-combination”, “Medium consumers-combination” and “Higher consumers-combination” patterns based on the intake of foods such as red meat, vegetables and fruits. The severity of symptoms was categorized into “Asymptomatic”, “Mild symptoms” and “Overt symptoms” classes based on health-related symptoms reported by the participants. Compared to the “Healthy” pattern, the other four patterns were all associated with an increased risk of esophageal disease. Similarly, the other two symptom classes present different degrees of increased risk of esophageal disease compared to the “Asymptomatic”. The nomograms reflect the good predictive ability of the model. Conclusion Among individuals aged 40–69 years in high incidence regions of upper gastrointestinal cancer, the results supplied that subjects with diets rich in livestock and poultry meat and low in fruits and vegetables and subjects with typical symptoms were at increased ESCC risk. The findings highlight the importance of considering food and symptom combinations in cancer risk evaluation. more...
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- 2022
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50. Locally enhanced surface plasmons and modulated 'hot-spots' in nanoporous gold patterns on atomically thin MoS2 with a comparison to SiO2 substrate
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Yi Hua, Aiming Yan, and Vinayak P. Dravid
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Nanostructure ,Materials science ,Physics and Astronomy (miscellaneous) ,Nanoporous ,Electron energy loss spectroscopy ,Surface plasmon ,Nanotechnology ,02 engineering and technology ,Substrate (electronics) ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,chemistry.chemical_compound ,chemistry ,Scanning transmission electron microscopy ,0210 nano-technology ,Molybdenum disulfide ,Plasmon - Abstract
Plasmonic phenomena in metals have garnered significant scientific and technological interest in the past decade. Despite many promising applications based on plasmonics, one remaining challenge is to control the surface geometry or morphology of the metallic structures, which can significantly affect the plasmonic properties of nanostructures. Here, we report the morphological modulation of gold (Au) nanopatterns on atomically thin layered molybdenum disulfide (MoS2), compared to Au nanopatterns grown on SiO2/Si substrate. We have used electron energy loss spectroscopy in a scanning transmission electron microscope to probe the locally enhanced surface plasmons in nanoporous Au patterns grown on SiO2/Si substrate as well as on single- and few-layer MoS2 flakes. Thin flakes of MoS2 as substrates significantly influence the morphology of Au patterns, which locally alters the plasmonic behavior. Features such as nanoscale pores exhibit plasmon localization with strong near fields, akin to “hot spots.” Bound... more...
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- 2016
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