Search

Adolescents with learning disabilities experience emotional imbalances due to repeated failure in learning situations. There is a clear need to create a Malayalam version of the Emotional Intelligence Scale (EIS) given the substantial correlation between emotional intelligence and learning impairments. An emotional intelligence scale that focuses largely on adolescents was created by the researcher by utilising a cross-sectional research approach. The data was collected from adolescents in eighth through twelfth grades aged 12 to 17 years old. The exploratory factor analysis revealed four main dimensions: Self-Awareness (10 items), Problem-Solving (4 items), Optimism (4 items), and Relationship Management (5 items). The EIS was determined to have a Cronbach Alpha and Split Half reliability of 0.88 and 0.86, respectively. The present study aimed to investigate the psychometric properties of the Emotional Intelligence Scale (EIS) in order to evaluate the emotional intelligence levels of adolescents who have learning disabilities. [ABSTRACT FROM AUTHOR]

In the main this paper discusses the addition of an edge uv 2 E(G) to a cycle graph Cn to obtain the 1-chorded cycle graph Cs1 n such that the total vertex stress of Cs1 n compared to the total vertex stress of Cn shows a maximum or minimum alteration over all uv 2 E(G). Furthermore, results for wheel graphs, helm graphs, flower graphs, sunlet graphs, sun graphs and prism graphs are also presented. Finally a heuristic algorithm is proposed which determines the total vertex stress in a general graph G. [ABSTRACT FROM AUTHOR]

Rab monomeric GTPases regulate specific aspects of vesicle transport in eukaryotes including coat recruitment, uncoating, fission, motility, target selection and fusion. Moreover, individual Rab proteins function at specific sites within the cell, for example the ER, golgi and early endosome. Importantly, the localization and function of individual Rab subfamily members are often conserved underscoring the significant contributions that model organisms such as Caenorhabditis elegans can make towards a better understanding of human disease caused by Rab and vesicle trafficking malfunction. With this in mind, a bioinformatics approach was first taken to identify and classify the complete C. elegans Rab family placing individual Rabs into specific subfamilies based on molecular phylogenetics. For genes that were difficult to classify by sequence similarity alone, we did a comparative analysis of intron position among specific subfamilies from yeast to humans. This two-pronged approach allowed the classification of 30 out of 31 C. elegans Rab proteins identified here including Rab31/Rab50, a likely member of the last eukaryotic common ancestor (LECA). Second, a molecular toolset was created to facilitate research on biological processes that involve Rab proteins. Specifically, we used Gateway-compatible C. elegans ORFeome clones as starting material to create 44 full-length, sequence-verified, dominant-negative (DN) and constitutive active (CA) rab open reading frames (ORFs). Development of this toolset provided independent research projects for students enrolled in a research-based molecular techniques course at California State University, East Bay (CSUEB).

Effluent produced during the electroplating process can contain high concentrations of heavy metals that can enter the environment and induce toxicity to aquatic organisms. Relatively high concentrations of zinc (Zn) and mercury (Hg) have been detected in treated electroplating industrial effluent (TEPIE), though the cytotoxic potential of these compounds has not been well assessed in fish gills. A novel cell line, Danio rerio gill (DrG), were exposed to TEPIE and concentrations of Zn, Hg, and Zn + Hg previously measured in treated effluent to evaluate the use of the DrG cell line following exposure to environmental pollutants. Several cytotoxic assays were employed to assess the effect of TEPIE, Zn, and Hg on this cell line. The percent cell viability was significantly reduced in a concentration-dependent manner following exposure to TEPIE, Zn, Hg, and Zn + Hg (p < 0.05) for 24 h, with additional morphological changes observed in exposure treatments relative to controls. Additionally, there was a significant induction of DNA damage detected in all exposure treatments determined through comet assay tail length. An increase in intracellular ROS generation was also observed in cells exposed to TEPIE, Zn, Hg, and Zn + Hg, corresponding to dose-dependent increases in apoptosis. Our study confirmed that TEPIE and the metals present in it induced cytotoxicity in the DrG cell line, demonstrating its usefulness as a model to explore relationships between pollutants and fish gills., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2021 Elsevier B.V. All rights reserved.)

The rapid growth of industrialization and urbanization results in deterioration of freshwater systems around the world, rescinding the ecological balance. Among many factors that lead to adverse effects in aquatic ecology, metals are frequently discharged into aquatic ecosystems from natural and anthropogenic sources. Metals are highly persistent and toxic substances in trace amounts and can potentially induce severe oxidative stress in aquatic organisms. In this study, adverse effects of the two metal elements zinc (maximum concentration of 167.25 mg/L) and mercury (104.2 mg/L) were examined using Chlorella vulgaris under acute and chronic exposure period (48 h and 7 days, respectively). The metal-induced adverse effects have been analyzed through photosynthetic pigment content, total protein content, reactive oxygen species (ROS) generation, antioxidant enzymatic activities, namely catalase and superoxide dismutase (SOD) along with morphological changes in C. vulgaris. Photosynthetic pigments were gradually reduced (~32-100% reduction) in a dose-dependent manner. Protein content was initially increased during acute (~8-12%) and chronic (~57-80%) exposure and decreased (~44-56%) at higher concentration of the two metals (80%). Under the two metal exposures, 5- to 7-fold increase in ROS generation indicated the induction of oxidative stress and subsequent modulations in antioxidant activities. SOD activity was varied with an initial increase (58-129%) followed by a gradual reduction (~3.7-79%), while ~1- to 12-fold difference in CAT activity was observed in all experimental condition (~83 to 1605%). A significant difference was observed in combined toxic exposure (Zn+Hg), while comparing the toxic endpoint data of individual metal exposure (Zn and Hg alone). Through this work, lethal effects caused by single and combined toxicity of zinc and mercury were assessed, representing the significance of appropriate monitoring system to trim down the release of metal contaminants into the aquatic ecosystems.

The microalga Chlorella vulgaris is one of the prominent and most widely distributed green microalgae found in aquatic environments, often used in toxicity tests due to its sensitivity to various pollutants. To examine the toxicity of metals found in the effluent discharges from an electroplating industry, physicochemical parameters in the microalga C. vulgaris were measured. pH, turbidity, total dissolved solids, color, and the concentrations of metals such as chromium (1.97 mg/L), mercury (104.2 mg/L), and zinc (167.25 mg/L) were found exceeding the permissible limits. Several endpoints such as total protein content, reactive oxygen species (ROS) production, photosynthetic pigment contents, and antioxidant enzymatic activities, including those of superoxide dismutase (SOD) and catalase (CAT), were measured in C. vulgaris in response to treated electroplating industrial effluent (TEPIE). In addition, concentration-dependent morphological changes were also observed in response to TEPIE. Under both acute and chronic TEPIE exposure, increase in the ROS level was observed indicating increased production of ROS in C. vulgaris cells. The total protein and chlorophyll contents were found to be gradually decreasing in an effluent concentration-dependent manner. Moreover, lower concentrations of effluent stimulated the antioxidant enzyme systems. A concentration-dependent increase was observed in both SOD and CAT enzymatic activities. The results indicated toxic impairments by the effluent on the function of C. vulgaris in response to both acute and chronic exposure, indicating an urgent need of proper treatment processes/modification of the existing one of TEPIE, with continuous monitoring of the discharge of the pollutants into the aquatic ecosystems using biological assays., (Copyright © 2019 Elsevier B.V. All rights reserved.)