397 results on '"Akk, Gustav"'
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2. Tabernanthalog and ibogainalog inhibit the α7 and α9α10 nicotinic acetylcholine receptors via different mechanisms and with higher potency than the GABAA receptor and CaV2.2 channel
3. UNC-49 is a redox-sensitive GABA A receptor that regulates the mitochondrial unfolded protein response cell nonautonomously
4. Comparison of Behavioral Effects of GABAergic Low- and High-Efficacy Neuroactive Steroids in the Zebrafish Larvae Assay.
5. Chemical, Pharmacological, and Structural Characterization of Novel Acrylamide-Derived Modulators of the GABAAReceptor
6. Mutational Analysis of Anesthetic Binding Sites and Their Effects on GABAA Receptor Activation and Modulation by Positive Allosteric Modulators of the α7 Nicotinic Receptor
7. Faculty Opinions recommendation of Gain-of-function and loss-of-function GABRB3 variants lead to distinct clinical phenotypes in patients with developmental and epileptic encephalopathies.
8. Perspective on the Relationship between GABAA Receptor Activity and the Apparent Potency of an Inhibitor
9. Mild chronic perturbation of inhibition severely alters hippocampal function
10. The Mechanism of Enantioselective Neurosteroid Actions on GABAA Receptors
11. Faculty Opinions recommendation of General Anesthesia and the Young Brain: The Importance of Novel Strategies with Alternate Mechanisms of Action.
12. UNC-49 is a redox-sensitive GABAA receptor that cell non-autonomously regulates the mitochondrial unfolded protein response
13. Ms. Rabia Moin: A Linchpin in the Road to Success of Current Neuropharmacology
14. Modulation of the mammalian GABA A receptor by type I and type II positive allosteric modulators of the α7 nicotinic acetylcholine receptor
15. Faculty Opinions recommendation of The inescapable drive to sleep: Overlapping mechanisms of sleep and sedation.
16. Mutational Analysis of Anesthetic Binding Sites and Their Effects on GABA A Receptor Activation and Modulation by Positive Allosteric Modulators of the α7 Nicotinic Receptor.
17. Enhanced GABAergic actions resulting from the coapplication of the steroid 3α-hydroxy-5α-pregnane-11,20-dione (alfaxalone) with propofol or diazepam
18. Activation of the Rat α1β2ε GABAA Receptor by Orthosteric and Allosteric Agonists
19. Faculty Opinions recommendation of Midazolam at Low Nanomolar Concentrations Affects Long-term Potentiation and Synaptic Transmission Predominantly via the α1-γ-Aminobutyric Acid Type A Receptor Subunit in Mice.
20. (+)-Catharanthine potentiates the GABAA receptor by binding to a transmembrane site at the β(+)/α(-) interface near the TM2-TM3 loop
21. Neurosteroid Modulation of GABAA Receptor Function by Independent Action at Multiple Specific Binding Sites
22. Meet the Editorial Board Member
23. The Mechanism of Enantioselective Neurosteroid Actions on GABA A Receptors.
24. Faculty Opinions recommendation of Thalamic T-Type Calcium Channels as Targets for Hypnotics and General Anesthetics.
25. Assessing potentiation of the (α4)3(β2)2 nicotinic acetylcholine receptor by the allosteric agonist CMPI
26. Activation of the α1β2γ2L GABAA Receptor by Physiological Agonists
27. Faculty Opinions recommendation of A Novel Etomidate Analog EL-0052 Retains Potent Hypnotic Effect and Stable Hemodynamics without Suppressing Adrenocortical Function.
28. The Sulfated Steroids Pregnenolone Sulfate and Dehydroepiandrosterone Sulfate Inhibit the α1β3γ2L GABAA Receptor by Stabilizing a Novel Nonconducting State
29. Perspective on the relationship between GABAA receptor activity and the apparent potency of an inhibitor
30. Modulation of the human ρ1 GABAA receptor by inhibitory steroids
31. 11-trifluoromethyl-phenyldiazirinyl neurosteroid analogues: potent general anesthetics and photolabeling reagents for GABAA receptors
32. Modulation of the mammalian GABAA receptor by type I and type II positive allosteric modulators of the α7 nicotinic acetylcholine receptor.
33. Faculty Opinions recommendation of Automated Intracellular Pharmacological Electrophysiology for Ligand-Gated Ionotropic Receptor and Pharmacology Screening.
34. The influence of the membrane on neurosteroid actions at GABA A receptors
35. Activation of the Rat α1β2ε GABA A Receptor by Orthosteric and Allosteric Agonists.
36. Intrasubunit and intersubunit steroid binding sites independently and additively mediate α1β2γ2L GABAA receptor potentiation by the endogenous neurosteroid allopregnanolone
37. Enhancement of Muscimol Binding and Gating by Allosteric Modulators of the GABA(A) Receptor: Relating Occupancy to State Functions
38. Faculty Opinions recommendation of Humulone Modulation of GABAA Receptors and Its Role in Hops Sleep-Promoting Activity.
39. Meet Our Editorial Board Member
40. Faculty Opinions recommendation of Competitive antagonism of etomidate action by diazepam: in vitro GABAA receptor and in vivo zebrafish studies.
41. A neurosteroid potentiation site can be moved among GABAA receptor subunits
42. Impact of human D398N single nucleotide polymorphism on intracellular calcium response mediated by α3β4α5 nicotinic acetylcholine receptors
43. Characteristics of concatemeric GABAA receptors containing α4/δ subunits expressed in Xenopus oocytes
44. Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence
45. Pharmacology of structural changes at the GABAA receptor transmitter binding site
46. Reduced Activation of the Synaptic-Type GABAA Receptor Following Prolonged Exposure to Low Concentrations of Agonists: Relationship between Tonic Activity and Desensitization
47. Faculty Opinions recommendation of Propofol Affects Cortico-Hippocampal Interactions via β3 Subunit-Containing GABAA Receptors.
48. Site-specific effects of neurosteroids on GABAA receptor activation and desensitization
49. Enhancement of Muscimol Binding and Gating by Allosteric Modulators of the GABAAReceptor: Relating Occupancy to State Functions
50. Author response: Site-specific effects of neurosteroids on GABAA receptor activation and desensitization
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