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• MOLLI and T1FLASH sequences can be used for T1mapping of the prostate. • Contrast media accumulation at the bladder base limits T1mapping. • In post-GBCA, T1FLASH yields superior image quality over MOLLI sequences. • T1FLASH demonstrates reduced artifact burden over MOLLI sequences. To assess artifact burden and image quality of different MRI T1 mapping techniques of the prostate. Participants with suspected prostate cancer (PCa) were prospectively enrolled from June-October 2022 and examined with multiparametric prostate MRI (mpMRI; 3 T scanner; T1wi, T2wi, DWI und DCE). T1 mapping was performed before and after administration of gadolinium-based contrast-agent (GBCA) using (i) a modified Look-Locker inversion (MOLLI) technique and (ii) a novel single-shot T1FLASH inversion recovery technique. T2wi, DWI, T1FLASH and MOLLI sequences were systematically examined regarding prevalence of artifacts and image quality using a 5-point Likert-Scale. A total of n = 100 patients were included (median age: 68 years). T1FLASH maps (pre-and post-GBCA) showed metal artifacts in 7% of cases and susceptibility artifacts in 1%. For MOLLI maps, pre-GBCA metal and susceptibility artifacts were documented in 6.5% of cases each. MOLLI maps post-GBCA showed artifacts in 59% of cases resulting primarily from urinary GBCA excretion and GBCA accumulation at the bladder base (p < 0.01 versus T1FLASH post-GBCA). Image quality for T1FLASH pre-GBCA was rated at a mean 4.9+/-0.4 and for MOLLI at 4.8+/-0.6 (p = 0.14). Post-GBCA image quality was rated at a mean 4.9+/-0.4 for T1FLASH and at 3.7+/-1.1 for MOLLI (p < 0.001). T1FLASH maps provide a fast and robust method for quantification of T1 relaxation times of the prostate. T1FLASH is suitable for T1 mapping of the prostate following administration of contrast agents, while MOLLI T1 mapping is impaired through GBCA accumulation at the bladder base leading to severe image artifacts and reduced image quality. [ABSTRACT FROM AUTHOR]

The review titled "Staging and Diagnostics of Rectal Cancer" aims to provide insight to imaging techniques in patients with rectal cancer.Rectal cancer is among the most common malignancies, with one of the highest mortality rates worldwide. Timely diagnosis and therapy of this cancer therefore has important socio-economic implications.Radiological imaging plays a major role in the planning of subsequent therapy. Modern tomographic imaging is used not only for initial diagnosis, but also for staging.The individual role of different imaging techniques in diagnosis of rectal cancer will be explained in detail, and their function in general. Furthermore, we will present relevant radiological research related.The increasing role of MRI-based local staging will be presented in detail in this review. Defined diagnostic criteria, based on common recommendations, will be explained. We will show how MRI-based local staging can support the initial diagnosis and follow-up examinations in collaboration with other medical specialties in therapeutic planning. In particular, we describe how MRI is capable of substantially influencing the determination of surgical procedures in rectal cancer., Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)

Purpose:  Cross-institutional establishment of standardized protocols for CT and MR imaging of primary liver and pancreas tumors in an oncological center., Materials and Methods:  This prospective dual-institution study was approved by the local IRBs. Minimum requirements (phases, sequences, slice thickness) for imaging of primary liver and pancreas tumors were defined and implemented at both sites. Between 06/19 and 08/19 in-house examinations were evaluated in terms of compliance with defined protocols and image quality. In addition, extramural examinations that were demonstrated at interdisciplinary tumor board meetings in the same study period were reviewed. Results were analyzed by means of descriptive statistics, and differences between centers, modalities and organs assessed (Fisher-exact Test, p < 0.05 deemed significant)., Results:  480 data sets (397 internal, 83 extramural) were included in this study and analyzed. Overall protocol compliance for in-house examinations was 93.5 % (371/397 datasets), without statistical significant difference between the two institutions (p = 0.0615). External studies met minimum requirements in 48.2 % (40/83 datasets). Regarding in-house imaging, significant differences were observed between CT of the liver and the pancreas (p < 0.05) and between CT and MRI of the pancreas (p < 0.05)., Conclusion:  As demonstrated in this pilot project, cross-institutional establishment of standardized imaging protocols is feasible with a compliance rate of more than 90 %. Standardized imaging protocols may serve as a quality indicator in oncological imaging, and over time, improve cross-institutional patient care., Key Points:   · Cross-institutional establishment of standardized imaging protocols is feasible with high compliance.. · Standards may serve as a quality indicator in oncological imaging.. · In perspective, cross-institutional patient care may be improved.., Citation Format: · Römermann I, Al-Bourini O, Seif Amir Hosseini A et al. Cross-insitutional standardization of imaging protocols - A pilot study within the scope of the Comprehensive Cancer Center Lower Saxony. Fortschr Röntgenstr 2021; 193: 410 - 416., Competing Interests: The authors declare that they have no conflict of interest., (Thieme. All rights reserved.)

Competing Interests: Disclosure The authors report no conflicts of interest in this work.