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Perovskite solar cells display potential as a renewable energy source because of their high-power conversion efficiency. However, there is limited understanding regarding the potential impact of perovskite on human health and the ecosystem. In this study, two sets of male Wistar albino rats received 35 injections of perovskite composite at a dosage of 0.372 mg/kg body weight. The animals underwent thorough examinations, encompassing morphometric, hematological, biochemical, histological, and behavioral analyses. Liver, kidney, and testis biopsies were processed and examined histologically. Additionally, two groups of mice (perovskite-treated and control mice, each with n = 10) underwent three behavioral tests: the Elevated Zero Maze test, Marble Burying test, and Light-Dark Box test. Perovskite-treated rats displayed a significant increase in levels of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, triglycerides, cholesterol, creatinine, blood urea nitrogen, white blood cells, and platelets. However, total bilirubin levels decreased, with no significant alteration in albumin values. Furthermore, exposure to perovskite composite resulted in a slight decrease in lactate dehydrogenase and red blood cell count. Histopathological examination revealed hepatic hydropic degeneration, Kupffer cells hypertrophy and hyperplasia, and renal hydropic degeneration, while testicular tissues remained unaffected. Moreover, behavioral changes were observed in perovskite-treated mice, including depression, anxiety, and compulsive burying activity. These findings suggest that exposure to perovskite can lead to significant hematological and biochemical changes, as well as hepatorenal histopathological alterations and behavioral changes. Additionally, chronic exposure to perovskite materials may induce structural and functional alterations in vital organs. [ABSTRACT FROM AUTHOR]

Congenital absence of teeth is the most commonly seen developmental dental anomaly in pediatric dental clinic, although agenesis of first permanent molar has the least frequency. Its prevalence in the maxilla ranges from(0.2 to 1.5)% and in the mandible no data had been reported. The etiology of this anomaly is not exactly specified; in general it may occur in association with oligodontia or other dental disturbances. Despite the rare occurrence of first permanent molars' agenesis, it has a significant effect on the treatment plan outcome, as it plays a major role in food mastication, vertical dimension support of the face, and anchorage of teeth against orthodontic forces. In this study we have described the clinical and radiographic findings of a rare case report among Jordanian pediatric population of congenitally missing bilateral maxillary and mandibular first permanent molars. [ABSTRACT FROM AUTHOR]