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Background: The objective of our study to analyze the data of the prenatal diagnosis of congenital malformations at the maternity and reproductive health hospital "Les Orangers" in Rabat and to identify the main anomalies detected, their percentage and their short-term outcome. Methods: This is a cross-sectional study conducted at the maternity and reproductive health hospital "Les Orangers" in Rabat, Morocco. The data was collected and reported on pre-established sheets and on the register of malformations of the hospital. Results: A total of 245 cases of congenital malformations comprising 470 types of congenital malformations were recorded out of a total of 43,923 births over a period of five and a half years, giving a prevalence of 5.58 per thousand. Prenatal diagnosis was made in a third of cases (33%), essentially during the 2nd-3rd trimester of pregnancy. The anomalies revealed by this antenatal diagnosis were dominated by urinary malformations in 70% and central nervous system anomalies in 67%, followed by other types of congenital anomalies in less than 40% of cases, while genetic problems were detected in 2.5%; this rate is underestimated since chromosomal abnormalities sometimes appear as syndromes, so that in some diseases, genetic changes are not separated from other abnormalities, and since more than half (50.7%) of cases presenting polymalformative syndromes not survived 77% of cases i.e. (48.5% of deaths and 28.5% of FDIU) and an etiological study was not carried out. Conclusion: Antenatal ultrasound allows early detection and monitoring of the evolution of congenital malformations, and thus the possibility of ensuring early and adequate management of these anomalies from birth. In our context, it is necessary to develop a prenatal screening program for congenital anomalies and a network of reference centers for the management of these anomalies in order to improve their prognosis. [ABSTRACT FROM AUTHOR]

Competing Interests: Les auteurs ne déclarent aucun conflit d’intérêts.

The idiopathic thrombocytopenic purpura (ITP) associated to a pregnancy is a frequent eventuality, and this association have a high risk. The mother platelet numeration cannot predict the fetal affection, only the mother antiplatelet antibodies rate have a predictive value. The obstetrical attitude is highly discussed and is conditioned by the fetus platelet rate. If the corticotherapy brings an improvement of the maternal and fetal platelet rate, the gammaglobulin therapeutic interest will be confirmed. Thanks to a ITP case associated to pregnancy and a literature review, we will try to appreciate this disease for a pregnant woman, evaluate its consequences on the pregnancy and approach the different steps of the taking care actions.