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5. The Saudi Critical Care Society practice guidelines on the management of COVID-19 in the ICU: Therapy section

Author

Alhazzani, Waleed, Alshahrani, Mohammed, Alshamsi, Fayez, Aljuhani, Ohoud, Eljaaly, Khalid, Hashim, Samaher, Alqahtani, Rakan, Alsaleh, Doaa, Al Duhailib, Zainab, Algethamy, Haifa, Al-Musawi, Tariq, Alshammari, Thamir, Alqarni, Abdullah, Khoujah, Danya, Tashkandi, Wail, Dahhan, Talal, Almutairi, Najla, Alserehi, Haleema A., Al-Yahya, Maytha, Al-Judaibi, Bandar, Arabi, Yaseen M., Abualenain, Jameel, Alotaibi, Jawaher M., Al bshabshe, Ali, Alharbi, Reham, Al-Hameed, Fahad, Elhazmi, Alyaa, Almaghrabi, Reem S., Almaghlouth, Fatma, Abedalthagafi, Malak, Al Khathlan, Noor, Al-Suwaidan, Faisal A., Bunyan, Reem F., Baw, Bandar, Alghamdi, Ghassan, Al Hazmi, Manal, Mandourah, Yasser, Assiri, Abdullah, Enani, Mushira, Alawi, Maha, Aljindan, Reem, Aljabbary, Ahmed, Alrbiaan, Abdullah, Algurashi, Fahd, Alsaawi, Abdulmohsen, Alenazi, Thamer H., Alsultan, Mohammed A., Alqahtani, Saleh A., Memish, Ziad, Al-Tawfiq, Jaffar A., and Al-jedai, Ahmed

Published
2022
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8. Treatment outcomes among tuberculosis patients in Jeddah, Saudi Arabia: Results of a community mobile outreach directly observed Treatment, Short-course (DOTS) project, compared to a standard facility-based DOTS: A randomized controlled trial

Author

Al-Sahafi, Abdullah, Al-Sayali, Mashal M., Mandoura, Najlaa, Shah, Hassan B.U., Al Sharif, Khalid, Almohammadi, Emad L., Abdul-Rashid, Ola A., Assiri, Muhammad, Buksh, Mohammed F., Alali, Mahmoud M., Al-Garni, Abdullah, Al-Garni, Fatima, Al-Zahrani, Abdullah, Khalawi, Alaa, Alawi, Maha, Moawwad, Abdulhamed L., Almalki, Abdulrahim I.A., and Al-Osaimi, Maataug M.

Published
2021
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9. Repurposing of antibacterial compounds for suppression of Mycobacterium tuberculosisdormancy reactivation by targeting resuscitation-promoting factors B

Author

Kumar, Geethu S., Dubey, Amit, Panda, Siva Prasad, Alawi, Maha M., Sindi, Anees A., Azhar, Esam I., Dwivedi, Vivek Dhar, and Agrawal, Sharad

Abstract

AbstractTuberculosis infection has always been a global concern for public health, and the mortality rate has increased tremendously every year. The ability of the resuscitation Mycobacterium tuberculosis(Mtb) from the dormant state is one of the major reasons for the epidemic spread of tuberculosis infection, especially latent tuberculosis infection (LTBI). The element that encourages resuscitation, RpfB (resuscitation-promoting factors B), is mostly in charge of bringing Mtbout of slumber. This reason makes RpfB a promising target for developing tuberculosis drugs because of the effects of latent tuberculosis. Therefore, this work was executed using a computational three-level screening of the Selleckhem antibiotics database consisting of 462 antibiotics against the ligand binding region of the RpfB protein, followed by an estimation of binding free energy for ideal identification and confirmation of potential RpfB inhibitor. Subsequently, three antibiotic drug molecules, i.e., Amikacin hydrate (−66.87 kcal/mol), Isepamicin sulphate (−60.8 kcal/mol), and Bekanamycin (−46.89 kcal/mol), were selected on the basis of their binding free energy value for further computational studies in comparison to reference ligand, 4-benzoyl-2-nitrophenyl thiocyanate (NPT7). Based on the intermolecular interaction profiling, 200 ns molecular dynamic simulation (MD), post-simulation analysis and principal component analysis (PCA), the selected antibiotics showed substantial stability with the RpfB protein compared to the NPT7 inhibitor. Conclusively based on the computational results, the preferred drugs can be potent inhibitors of the RpfB protein, which can be further validated using in vivoresearch and in vitroenzyme inhibition to understand their therapeutic activity against tuberculosis infection.Communicated by Ramaswamy H. Sarma

Published
2024
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11. Antimicrobial resistance: A round table discussion on the “One Health” concept from the Gulf Cooperation Council Countries. Part Two: A focus on Human Health

Author

Al-Maani, Amal Saif, Al-Abdely, Hail M., Balkhy, Hanan, Al-Katheeri, Huda Amer, Al-Fadhli, Mariam, Abdulrazzaq, Najiba M., Al-Khawaja, Safaa, Hawsawi, Abdulelah, Gwizani, Abdullah AL, Amri, Abdulrahman AL, Saedy, Abdulrahman AL, Omran, Abeer, Qunaibet, Ada, Othman, Adel AL, Rashidi, Afaf AL, Alhakawi, Ahmad, Harbi, Ahmed AL, El-Saed, Aiman, Alaa, Ali AL, Doweriej, Ali AL, Sharif, Ali Al, Somily, Ali Al, Doweriej, Ali Al, Radidiah, Ali, Ruwaili, Alya AL, Gadalla, Azaheer, Binhelel, Bandar S., Alshammari, Basim, Hussain, Ehab M., Rabiah, Fahad AL, Bogoumi, Faisal AL, Saeed, Faroog, Anazi, Fatimah AL, Poff, Gregory, Abdely, Hail Mater Al, Roushdy, Hala Moustafa, Albatshan, Hamad, Hathout, Hanan Mohamed, Bonnie, Henry Baffoe, Modaimegh, Hind AL, Zowawi, Hosam, Bukhari, Huda, Rashidi, Hussain AL, Jafali, Ibrahim AL, Qassem, Ibrahim, Tawfiq, Jaffar, Gramish, Jawaher, AL-Alawi, Maha, Aly, Mahmoud, Jeraisy, Majed Al, Alghoraibi, Majed, Alshamarani, Majid, Dalatony, Mervat Mohamed El, Ali, Mohamed Abdellatif, Quwazini, Mohamed Al, Abakhail, Mohammed, Essa, Mohammed AL, Shaalan, Mohammed AL, Balla, Munee, Enani, Musheera, Abuhasan, Muslim Younis, Attas, Nadia AL, Osman, Nahla, Alharbi, Naif, Mutairi, Noof AL, Fattoh, Nora, ALIbrahim, Raed, Hababi, Raed, Ibrahim, Raed, Shahrani, Saed Al, Jabbar, Saeed AL, Althawadi, Sahar, Aljohani, Sameera, Hajjar, Sami AL, Nazeer, Sayd, Jumaa, Suliman AL, Mahmoud, Suliman AL, Uzzaman, Taher, Oreibi, Talal AL, Sadig, Tarig, Desin, Taseen, Enazi, Thamer, Rabmo, Thuria, Nasser, Wafaa AL, Sultan, Zeinab Abbas, Qahtani, Abdullah AL, Shammrai, Abdullah AL, Otaibi, Abdulmalik AL, Shehri, Asma AL, Zahrani, Asma AL, Khazam, Bassem Abu, Harbi, Faisal AL, Suwayeh, Hani AL, Balani, Mansour AL, Rubaian, Meshal AL, Albelowi, Mohammed, Mutairi, Tareq AL, Dagunton, Nimfa, Aamar, Kholoud AL, Alsaqer, Taghreed A., Srinivasan, Arjun, Aidara-Kane, Awa, Allegranzi, Benedetta, Erlacher-Vindel, Elisabeth, Houfi, Ashraf El, Thomsen, Jens, Jamal, Khouloud, Jasim, Laila Mohamed, Alfaresi, Mubarak, Abdulrazzaq, Najiba M, Omar, Zulfa, Alsalman, Jameela, Khawajah, Safaa, Alkatheri, Huda, Ajmi, Jameela Al, Thani, Mohammed bin Hamad Al, Ishaq, Moza Al, Sharaf, Nahla, Balkhy, Hanan H., Zowawi, Hosam M., Alshamrani, Majid M., Somily, Ali M., and Al-Quwaizani, Mohammad A.

Published
2018
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12. Antimicrobial resistance: A round table discussion on the “One Health” concept from the Gulf Cooperation Council Countries. Part One: A focus on Leadership

Author

Al-Maani, Amal Saif, Al-Abdely, Hail M., Balkhy, Hanan, Al-Katheeri, Huda Amer, Al-Fadhli, Mariam, Abdulrazzaq, Najiba M., Al-Khawaja, Safaa, Hawsawi, Abdulelah, ALGwizani, Abdullah, Amri, Abdulrahman AL, Saedy, Abdulrahman AL, Omran, Abeer, Qunaibet, Ada, Othman, Adel AL, Rashidi, Afaf AL, Alhakawi, Ahmad, Harbi, Ahmed AL, El-Saed, Aiman, Alaa, Ali AL, Doweriej, Ali AL, Sharif, Ali Al, Somily, Ali Al, AlDoweriej, Ali, Radidiah, Ali, Ruwaili, Alya AL, Gadalla, Azaheer, Binhelel, Bandar S., Alshammari, Basim, Hussain, Ehab M., Rabiah, Fahad AL, Bogoumi, Faisal AL, Saeed, Faroog, Anazi, Fatimah AL, Poff, Gregory, Abdely, Hail Mater Al, Roushdy, Hala Moustafa, Albatshan, Hamad, Hathout, Hanan Mohamed, Bonnie, Henry Baffoe, Modaimegh, Hind AL, Zowawi, Hosam, Bukhari, Huda, Rashidi, Hussain AL, Jafali, Ibrahim AL, Qassem, Ibrahim, Tawfiq, Jaffar, Gramish, Jawaher, AL-Alawi, Maha, Aly, Mahmoud, Jeraisy, Majed Al, Alghoraibi, Majed, Alshamarani, Majid, Dalatony, Mervat Mohamed El, Ali, Mohamed Abdellatif, Quwazini, Mohamed Al, Abakhail, Mohammed, Essa, Mohammed AL, Shaalan, Mohammed AL, Balla, Munee, Enani, Musheera, Abuhasan, Muslim Younis, Attas, Nadia AL, Osman, Nahla, Alharbi, Naif, Mutairi, Noof AL, Fattoh, Nora, ALIbrahim, Raed, Hababi, Raed, Ibrahim, Raed, Shahrani, Saed Al, Jabbar, Saeed AL, Althawadi, Sahar, Aljohani, Sameera, Hajjar, Sami AL, Nazeer, Sayd, Jumaa, Suliman AL, Mahmoud, Suliman AL, Uzzaman, Taher, Oreibi, Talal AL, Sadig, Tarig, Desin, Taseen, Enazi, Thamer, Rabmo, Thuria, Nasser, Wafaa AL, Sultan, Zeinab Abbas, Qahtani, Abdullah AL, Shammrai, Abdullah AL, Otaibi, Abdulmalik AL, Shehri, Asma AL, Zahrani, Asma AL, Khazam, Bassem Abu, Suwayeh, Hani AL, Balani, Mansour AL, Rubaian, Meshal AL, Albelowi, Mohammed, Mutairi, Tareq AL, Dagunton, Nimfa, Mutlaq, Alaa, Mutairi, Diana AL, Otaibi, Hind AL, Rashoud, Isra AL, Aamar, Kholoud AL, Alsaqer, Taghreed A., Srinivasan, Arjun, Aidara-Kane, Awa, Allegranzi, Benedetta, Erlacher-Vindel, Elisabeth, Houfi, Ashraf El, Thomsen, Jens, Jamal, Khouloud, Jasim, Laila Mohamed, Alfaresi, Mubarak, Omar, Zulfa, Alsalman, Jameela, Khawajah, Safaa, Alkatheri, Huda, Ajmi, Jameela Al, Thani, Mohammed bin Hamad Al, Ishaq, Moza Al, Sharaf, Nahla, Balkhy, Hanan H., Albatshan, Hamad A., Alshamrani, Majid M., and Alhawsawi, Abdulelah M.

Published
2018
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15. Epidemiology of tuberculosis in Saudi Arabia following the implementation of end tuberculosis strategy: Analysis of the surveillance data 2015-2019.

Author

Alawi, Maha M., Alserehi, Haleema A., Ali, Ahmed O., Albalawi, Abeer M., Alanizi, Mashael K., Nabet, Fatima M., Alkamaly, Modhi A., Assiri, Abdullah M., Jokhdar, Hani, Qutub, Mohammed O., khoja, Moahmmed A., Azhar, Esam I., Taskandi, Wael A., Sindi, Annes A., and Yasir, Muhammad

Subjects
TUBERCULOSIS, EPIDEMIOLOGY, DATA analysis, MULTIDRUG resistance
Abstract

Copyright of Saudi Medical Journal is the property of Saudi Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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18. An Updated Review on Monkeypox Viral Disease: Emphasis on Genomic Diversity

Author

Rabaan, Ali A., primary, Alasiri, Nada A., additional, Aljeldah, Mohammed, additional, Alshukairiis, Abeer N., additional, AlMusa, Zainab, additional, Alfouzan, Wadha A., additional, Abuzaid, Abdulmonem A., additional, Alamri, Aref A., additional, Al-Afghani, Hani M., additional, Al-baghli, Nadira, additional, Alqahtani, Nawal, additional, Al-baghli, Nadia, additional, Almoutawa, Mashahed Y., additional, Mahmoud Alawi, Maha, additional, Alabdullah, Mohammed, additional, Bati, Neda A. Al, additional, Alsaleh, Abdulmonem A., additional, Tombuloglu, Huseyin, additional, Arteag-Livias, Kovy, additional, Al-Ahdal, Tareq, additional, Garout, Mohammed, additional, and Imran, Mohd, additional

Published
2023
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19. A Multifaceted Computational Approach to Understanding the MERS-CoV Main Protease and Brown Algae Compounds' Interaction.

Author

Gattan, Hattan S., Mahmoud Alawi, Maha, Bajrai, Leena H., Alandijany, Thamir A., Alsaady, Isra M., El-Daly, Mai M., Dwivedi, Vivek Dhar, and Azhar, Esam I.

Abstract

Middle East Respiratory Syndrome (MERS) is a viral respiratory disease caused b a special type of coronavirus called MERS-CoV. In the search for effective substances against the MERS-CoV main protease, we looked into compounds from brown algae, known for their medicinal benefits. From a set of 1212 such compounds, our computer-based screening highlighted four—CMNPD27819, CMNPD1843, CMNPD4184, and CMNPD3156. These showed good potential in how they might attach to the MERS-CoV protease, comparable to a known inhibitor. We confirmed these results with multiple computer tests. Studies on the dynamics and steadiness of these compounds with the MERS-CoV protease were performed using molecular dynamics (MD) simulations. Metrics like RMSD and RMSF showed their stability. We also studied how these compounds and the protease interact in detail. An analysis technique, PCA, showed changes in atomic positions over time. Overall, our computer studies suggest brown algae compounds could be valuable in fighting MERS. However, experimental validation is needed to prove their real-world effectiveness. [ABSTRACT FROM AUTHOR]

Published
2023
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27. Bacterial Community and Genomic Analysis of Carbapenem-Resistant Acinetobacter baumannii Isolates from the Environment of a Health Care Facility in the Western Region of Saudi Arabia

Author

Yasir, Muhammad, primary, Subahi, Abdullah Mohammad, additional, Shukri, Hani A., additional, Bibi, Fehmida, additional, Sohrab, Sayed Sartaj, additional, Alawi, Maha, additional, Sindi, Anees A., additional, Jiman-Fatani, Asif A., additional, and Azhar, Esam I., additional

Published
2022
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28. Effectiveness of Antimicrobial Stewardship Program in Long-Term Care: A Five-Year Prospective Single-Center Study

Author

Alawi, Maha Mahmoud, primary, Tashkandi, Wail A, additional, Basheikh, Mohamed A, additional, Warshan, Faten M, additional, Ghobara, Hazem Ahmed, additional, Ramos, Rosemarie B., additional, Guiriba, Mary Leilani, additional, Ayob, Omar, additional, Janah, Safiah Saad, additional, Sindi, Anees Ahmad, additional, Abdulhamid Ahmed, Suheib Ali, additional, Dammnan, Salah, additional, Azhar, Esam Ibraheem, additional, Rabaan, Ali A., additional, Alnahdi, Salma, additional, and Bamahakesh, Maged Mohammed, additional

Published
2022
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30. Prevalence and Epidemiological Trends in Mortality Due to COVID-19 in Saudi Arabia

Author

Alissa, Dema A., primary, Aburas, Wejdan, additional, Almudaiheem, Hajar Y., additional, Aseri, Zohair Al, additional, Alrabiah, Fahad, additional, Ezzat, Hatoon, additional, Moulana, Ashraf A., additional, Alawi, Maha M., additional, Al-mutairy, Eid, additional, Alaama, Tareef, additional, Alamri, Mohammed S., additional, Bamousa, Manal S., additional, Alshehri, Adel A., additional, Alosaimi, Mohammed H., additional, Devol, Edward Bentz, additional, and Al-jedai, Ahmed H., additional

Published
2021
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31. The Saudi Critical Care Society Practice Guidelines on the Management of COVID-19 in the ICU: Therapy Section

Author

Alhazzani, Waleed, primary, Alshahrani, Mohammed, additional, Alshamsi, Fayez, additional, Aljuhani, Ohoud, additional, Eljaaly, Khalid, additional, Hashim, Samaher, additional, Alqahtani, Rakan, additional, Alsaleh, Doaa, additional, Duhailib, Zainab Al, additional, Algethamy, Haifa, additional, Al-Musawi, Tariq, additional, Alshammari, Thamir, additional, Alqarni, Abdullah, additional, Khoujah, Danya, additional, Tashkandi, Wail, additional, Dahhan, Talal, additional, Almutairi, Najla, additional, Alserehi, Haleema A., additional, Al-Yahya, Maytha, additional, Al-Judaibi, Bandar, additional, Arabi, Yaseen M, additional, Abualenain, Jameel, additional, Alotaibi, Jawaher M., additional, Albshabshe, Ali, additional, Alharbi, Reham, additional, Al-Hameed, Fahad, additional, Elhazmi, Alyaa, additional, Almaghrabi, Reem S., additional, Almaghlouth, Fatma, additional, Abedalthagafi, Malak, additional, Khathlan, Noor Al, additional, Al-Suwaidan, Faisal A., additional, Bunyan, Reem F., additional, Baw, Bandar, additional, Alghamdi, Ghassan, additional, Hazmi, Manal Al, additional, Mandourah, Yasser, additional, Assiri, Abdullah, additional, Enani, Mushira, additional, Alawi, Maha, additional, Aljindan, Reem, additional, Aljabbary, Ahmed, additional, Alrbiaan, Abdullah, additional, Algurashi, Fahd, additional, Alsaawi, Abdulmohsen, additional, Alenazi, Thamer H., additional, Alsultan, Mohammed A., additional, Alqahtani, Saleh A., additional, Memish, Ziad, additional, Al-Tawfiq, Jaffar A., additional, and Al-Jedai, Ahmed, additional

Published
2021
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35. A stepwise introduction of a successful antimicrobial stewardship program

Author

Alawi, Maha M. and Darwesh, Bayan M.

Subjects
Adult, Male, Young Adult, Anti-Infective Agents, Saudi Arabia, Humans, Original Article, Female, Middle Aged, Aged
Abstract

Objectives To analyze and evaluate the safety and cost-effectiveness of a gradually-implemented antimicrobial stewardship programs (ASP) in a tertiary care center. Methods Prospective data were collected from an ASP that was gradually introduced between April 2012 and December 2013 in 6 hospital departments, over successive periods of 3 months each. A multidisciplinary team supervised antibiotic use and regulated pharmacy dispensations of a list of restricted antimicrobials (RAs). Indicators were prospectively monitored and included hospital mortality as the safety indicator; incidence of multi-drug resistance (MDR) infections as the effectiveness indicator, RA cost savings as the cost-effectiveness indicator and RA consumption indicated the process implementation. Results Between 2012 and 2014, dispensations of RAs decreased by 67% and prescriptions by 75%; no increase in mortality rate was observed. Microbiologically, there was a decreasing trend of incidence across all monitored infections, but this was only significant for Acinetobacter baumannii (p=0.007). Cost analysis showed a decrease in expenditure for RAs, with an average monthly saving of up to 326,020USD. Conclusions Stepwise implementation of ASPs is a safe and cost-effective strategy for improving antibiotic prescribing practice and to reduce multi-drug resistance.

Published
2016

39. Development and validation of different indirect ELISAs for MERS-CoV serological testing

Author

Hashem, Anwar M., primary, Al-amri, Sawsan S., additional, Al-subhi, Tagreed L., additional, Siddiq, Loai A., additional, Hassan, Ahmed M., additional, Alawi, Maha M., additional, Alhabbab, Rowa Y., additional, Hindawi, Salwa I., additional, Mohammed, Osama B., additional, Amor, Nabil S., additional, Alagaili, Abdulaziz N., additional, Mirza, Ahmed A., additional, and Azhar, Esam I., additional

Published
2019
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40. Antimicrobial resistance: A round table discussion on the “One Health” concept from the Gulf Cooperation Council Countries. Part Two: A focus on Human Health

Author

Balkhy, Hanan H., primary, Zowawi, Hosam M., additional, Alshamrani, Majid M., additional, Allegranzi, Benedetta, additional, Srinivasan, Arjun, additional, Al-Abdely, Hail M., additional, Somily, Ali M., additional, Al-Quwaizani, Mohammad A., additional, Al-Maani, Amal Saif, additional, Balkhy, Hanan, additional, Al-Katheeri, Huda Amer, additional, Al-Fadhli, Mariam, additional, Abdulrazzaq, Najiba M., additional, Al-Khawaja, Safaa, additional, Hawsawi, Abdulelah, additional, Gwizani, Abdullah AL, additional, Amri, Abdulrahman AL, additional, Saedy, Abdulrahman AL, additional, Omran, Abeer, additional, Qunaibet, Ada, additional, Othman, Adel AL, additional, Rashidi, Afaf AL, additional, Alhakawi, Ahmad, additional, Harbi, Ahmed AL, additional, El-Saed, Aiman, additional, Alaa, Ali AL, additional, Doweriej, Ali AL, additional, Sharif, Ali Al, additional, Somily, Ali Al, additional, Doweriej, Ali Al, additional, Radidiah, Ali, additional, Ruwaili, Alya AL, additional, Gadalla, Azaheer, additional, Binhelel, Bandar S., additional, Alshammari, Basim, additional, Hussain, Ehab M., additional, Rabiah, Fahad AL, additional, Bogoumi, Faisal AL, additional, Saeed, Faroog, additional, Anazi, Fatimah AL, additional, Poff, Gregory, additional, Abdely, Hail Mater Al, additional, Roushdy, Hala Moustafa, additional, Albatshan, Hamad, additional, Hathout, Hanan Mohamed, additional, Bonnie, Henry Baffoe, additional, Modaimegh, Hind AL, additional, Zowawi, Hosam, additional, Bukhari, Huda, additional, Rashidi, Hussain AL, additional, Jafali, Ibrahim AL, additional, Qassem, Ibrahim, additional, Tawfiq, Jaffar, additional, Gramish, Jawaher, additional, AL-Alawi, Maha, additional, Aly, Mahmoud, additional, Jeraisy, Majed Al, additional, Alghoraibi, Majed, additional, Alshamarani, Majid, additional, Dalatony, Mervat Mohamed El, additional, Ali, Mohamed Abdellatif, additional, Quwazini, Mohamed Al, additional, Abakhail, Mohammed, additional, Essa, Mohammed AL, additional, Shaalan, Mohammed AL, additional, Balla, Munee, additional, Enani, Musheera, additional, Abuhasan, Muslim Younis, additional, Attas, Nadia AL, additional, Osman, Nahla, additional, Alharbi, Naif, additional, Mutairi, Noof AL, additional, Fattoh, Nora, additional, ALIbrahim, Raed, additional, Hababi, Raed, additional, Ibrahim, Raed, additional, Shahrani, Saed Al, additional, Jabbar, Saeed AL, additional, Althawadi, Sahar, additional, Aljohani, Sameera, additional, Hajjar, Sami AL, additional, Nazeer, Sayd, additional, Jumaa, Suliman AL, additional, Mahmoud, Suliman AL, additional, Uzzaman, Taher, additional, Oreibi, Talal AL, additional, Sadig, Tarig, additional, Desin, Taseen, additional, Enazi, Thamer, additional, Rabmo, Thuria, additional, Nasser, Wafaa AL, additional, Sultan, Zeinab Abbas, additional, Qahtani, Abdullah AL, additional, Shammrai, Abdullah AL, additional, Otaibi, Abdulmalik AL, additional, Shehri, Asma AL, additional, Zahrani, Asma AL, additional, Khazam, Bassem Abu, additional, Harbi, Faisal AL, additional, Suwayeh, Hani AL, additional, Balani, Mansour AL, additional, Rubaian, Meshal AL, additional, Albelowi, Mohammed, additional, Mutairi, Tareq AL, additional, Dagunton, Nimfa, additional, Aamar, Kholoud AL, additional, Alsaqer, Taghreed A., additional, Aidara-Kane, Awa, additional, Erlacher-Vindel, Elisabeth, additional, Houfi, Ashraf El, additional, Thomsen, Jens, additional, Jamal, Khouloud, additional, Jasim, Laila Mohamed, additional, Alfaresi, Mubarak, additional, Abdulrazzaq, Najiba M, additional, Omar, Zulfa, additional, Alsalman, Jameela, additional, Khawajah, Safaa, additional, Alkatheri, Huda, additional, Ajmi, Jameela Al, additional, Thani, Mohammed bin Hamad Al, additional, Ishaq, Moza Al, additional, and Sharaf, Nahla, additional

Published
2018
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41. Antimicrobial resistance: A round table discussion on the “One Health” concept from the Gulf Cooperation Council Countries. Part One: A focus on Leadership

Author

Balkhy, Hanan H., primary, Zowawi, Hosam, additional, Albatshan, Hamad A., additional, Alshamrani, Majid M., additional, Aidara-Kane, Awa, additional, Erlacher-Vindel, Elisabeth, additional, Alhawsawi, Abdulelah M., additional, Al-Maani, Amal Saif, additional, Al-Abdely, Hail M., additional, Balkhy, Hanan, additional, Al-Katheeri, Huda Amer, additional, Al-Fadhli, Mariam, additional, Abdulrazzaq, Najiba M., additional, Al-Khawaja, Safaa, additional, Hawsawi, Abdulelah, additional, ALGwizani, Abdullah, additional, Amri, Abdulrahman AL, additional, Saedy, Abdulrahman AL, additional, Omran, Abeer, additional, Qunaibet, Ada, additional, Othman, Adel AL, additional, Rashidi, Afaf AL, additional, Alhakawi, Ahmad, additional, Harbi, Ahmed AL, additional, El-Saed, Aiman, additional, Alaa, Ali AL, additional, Doweriej, Ali AL, additional, Sharif, Ali Al, additional, Somily, Ali Al, additional, AlDoweriej, Ali, additional, Radidiah, Ali, additional, Ruwaili, Alya AL, additional, Gadalla, Azaheer, additional, Binhelel, Bandar S., additional, Alshammari, Basim, additional, Hussain, Ehab M., additional, Rabiah, Fahad AL, additional, Bogoumi, Faisal AL, additional, Saeed, Faroog, additional, Anazi, Fatimah AL, additional, Poff, Gregory, additional, Abdely, Hail Mater Al, additional, Roushdy, Hala Moustafa, additional, Albatshan, Hamad, additional, Hathout, Hanan Mohamed, additional, Bonnie, Henry Baffoe, additional, Modaimegh, Hind AL, additional, Bukhari, Huda, additional, Rashidi, Hussain AL, additional, Jafali, Ibrahim AL, additional, Qassem, Ibrahim, additional, Tawfiq, Jaffar, additional, Gramish, Jawaher, additional, AL-Alawi, Maha, additional, Aly, Mahmoud, additional, Jeraisy, Majed Al, additional, Alghoraibi, Majed, additional, Alshamarani, Majid, additional, Dalatony, Mervat Mohamed El, additional, Ali, Mohamed Abdellatif, additional, Quwazini, Mohamed Al, additional, Abakhail, Mohammed, additional, Essa, Mohammed AL, additional, Shaalan, Mohammed AL, additional, Balla, Munee, additional, Enani, Musheera, additional, Abuhasan, Muslim Younis, additional, Attas, Nadia AL, additional, Osman, Nahla, additional, Alharbi, Naif, additional, Mutairi, Noof AL, additional, Fattoh, Nora, additional, ALIbrahim, Raed, additional, Hababi, Raed, additional, Ibrahim, Raed, additional, Shahrani, Saed Al, additional, Jabbar, Saeed AL, additional, Althawadi, Sahar, additional, Aljohani, Sameera, additional, Hajjar, Sami AL, additional, Nazeer, Sayd, additional, Jumaa, Suliman AL, additional, Mahmoud, Suliman AL, additional, Uzzaman, Taher, additional, Oreibi, Talal AL, additional, Sadig, Tarig, additional, Desin, Taseen, additional, Enazi, Thamer, additional, Rabmo, Thuria, additional, Nasser, Wafaa AL, additional, Sultan, Zeinab Abbas, additional, Qahtani, Abdullah AL, additional, Shammrai, Abdullah AL, additional, Otaibi, Abdulmalik AL, additional, Shehri, Asma AL, additional, Zahrani, Asma AL, additional, Khazam, Bassem Abu, additional, Suwayeh, Hani AL, additional, Balani, Mansour AL, additional, Rubaian, Meshal AL, additional, Albelowi, Mohammed, additional, Mutairi, Tareq AL, additional, Dagunton, Nimfa, additional, Mutlaq, Alaa, additional, Mutairi, Diana AL, additional, Otaibi, Hind AL, additional, Rashoud, Isra AL, additional, Aamar, Kholoud AL, additional, Alsaqer, Taghreed A., additional, Srinivasan, Arjun, additional, Allegranzi, Benedetta, additional, Houfi, Ashraf El, additional, Thomsen, Jens, additional, Jamal, Khouloud, additional, Jasim, Laila Mohamed, additional, Alfaresi, Mubarak, additional, Omar, Zulfa, additional, Alsalman, Jameela, additional, Khawajah, Safaa, additional, Alkatheri, Huda, additional, Ajmi, Jameela Al, additional, Thani, Mohammed bin Hamad Al, additional, Ishaq, Moza Al, additional, and Sharaf, Nahla, additional

Published
2018
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46. Demographic distribution and transmission potential of influenza A and 2009 pandemic influenza A H1N1 in pilgrims

Author

Ashshi, Ahmed, primary, Azhar, Esam, additional, Johargy, Ayman, additional, Asghar, Atif, additional, Momenah, Aiman, additional, Turkestani, Abdulhafeez, additional, Alghamdi, Saad, additional, Memish, Ziad, additional, Al-Ghamdi, Ahmed, additional, Alawi, Maha, additional, El-Kafrawy, Sherif, additional, Farouk, Mohomed, additional, Harakeh, Steve, additional, Kumosani, Taha, additional, Makhdoum, Hatim, additional, and Barbour, Elie K, additional

Published
2014
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47. Non-contiguous finished genome sequence and description of Corynebacterium jeddahense sp. nov.

Author

Edouard, Sophie, primary, Bibi, Fehmida, additional, Dhamodharan, Ramasamy, additional, Lagier, Jean-Christophe, additional, Azhar, Esam Ibraheen, additional, Robert, Catherine, additional, Caputo, Aurelia, additional, Yasir, Muhammad, additional, Jiman-Fatani, Asif Ahmad, additional, Alawi, Maha, additional, Fournier, Pierre-Edouard, additional, and Raoult, Didier, additional

Published
2014
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48. Transposable elements in Escherichia coli antimicrobial resistance

Author

Iyer, Archana, primary, Barbour, Elie, additional, Azhar, Esam, additional, Salabi, Alaaeddin Ali El, additional, Hassan, Hani Mutlak A., additional, Qadri, Ishtiaq, additional, Chaudhary, Adeel, additional, Abuzenadah, Adel, additional, Kumosani, Taha, additional, Damanhouri, Ghazi, additional, Alawi, Maha, additional, Na’was, Tarek, additional, Nour, Afif M. Abdel, additional, and Harakeh, Steve, additional

Published
2013
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49. Viral Infection and Obesity: Current Status and Future Prospective

Author

Sartaj Sohrab, Sayed, Kamal, Mohammad /inits> A.<, L. Atkinson, Richard, M. Alawi, Maha, and I. Azhar, Esam

Abstract

Background: The association of pathogenic viruses with obesity has now been well-known in both human and animals. Globally, human obesity has become a serious problem leading to the emergence of multiple lifethreatening diseases. Adenoviruses contribute a significant role in the induction of obesity by affecting various pathways. Due to impaired immunity, obese individuals are more prone to nosocomial infections leading to complications of obesity. In contrast, several other important factors contributing to human obesity are known. Methods: Currently, many published reports showed strong evidence of the role and linkage of Ad36 infection in human obesity. The Ad36 pathogenesis effect on the hepatic steatosis reduces leptin gene expression, reduced antibody response in vaccination, reduces immune system, insulin sensitivity, increases glucose uptake, activates the lipogenic and pro-inflammatory pathways in adipose tissue increases the level of Macrophage Chemo attractant Protein-1 leading chronic inflammation and affect lipid metabolism. Results: The E4-ORF1 gene of Ad36 play an important role in the induction of adipogenesis and regulation of adipocyte differentiation and also known to activate the sensitizing effect of insulin. The use of E4-ORF1gene as a ligand to develop new drugs against diabetes and the prevention of Ad36 infection by an effective vaccination will attract researchers and open new area of research in the field of obesity and obesity-related multiple diseases. Conclusion: Therefore, the identification and management of important contributory factors by identifying the regulation of adipocyte differentiation leading to a chronic condition like adipogenesis and insulin resistance resulting in obesity is an urgent requirement globally for human health.

Published
2012
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50. Draft genome sequence of a clinical Acinetobacter baumanniiisolate of new sequence type ST1688 from Saudi Arabia

Author

Yasir, Muhammad, Shah, Muhammad Waseem, Jiman-Fatani, Asif A., Almasaudi, Saad B., Ahmad, Hussain, Alawi, Maha, and Azhar, Esam I.

Abstract

Acinetobacter baumanniihas emerged as a prevalent multidrug-resistant nosocomial pathogen worldwide. Here we report the draft genome sequence of A. baumanniistrain Ab174 isolated from a neonatal patient diagnosed with acute peritonitis.

Published
2019
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