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The prospects for the human embryos genome editing cause intense debates both in the scientific community and in general public. While the main attention of scientists is focused on the safety, effectiveness and clinical feasibility of the inherited genome editing, the public pays attention to the bioethical aspects of the issue - the prospects of a baby design, the development of new forms of social inequality and intervention in human evolution. The authors conducted an interdisciplinary analysis of medical genetics and bioethical issues of human embryo genome editing, revealed the possibilities and limitations of genome editing technology, and considered the specifics of ethical discussions. The conceptualization of the main approaches of natural and social sciences in a general theoretical framework made it possible not only to take into account the complex nature of the issues, but also to create the prerequisites for its further productive discussion.

Novel exo-nido-ruthenacarboranes, 5,6,10-[CI(Ph3P)2Ru]-5,6,10-μ-(H)3-10-H-7,8-R2C2B9H6 (1; R = H, structurally characterized by an X-ray diffraction study, and 2; R = Me) have been prepared by reaction of RuCl2 (PPh3)3 and [nido-7,8-R2C2B9H10]− K+ in diethyl ether-tetrahydrofuran; in the solid state clusters 1 and 2 contain tridentate nido–carborane ligands bound to the RuII atom through three Ru—H—B bridging hydrogen bonds, whereas in solution they exist as an equilibrium mixture of isomeric exo-nido-bis(triphenylphosphine)chlorohydridoruthenacarboranes formed as a result of the cleavage of one of the Ru—H—B bonds with the formation of a new Ru—B σ-bond and a simultaneous hydrogen atom shift to the metal atom.

Wavefront reversal and compensation of phase distortions in fiber waveguides with a liquid light-guiding core was observed for the first time. The use of benzene as an active medium placed in quartz capillaries made it possible to reduce the threshold for the observation of stimulated Brillouin scattering and wavefront reversal.